Myositis. Medical search. Definitions

Inflammation of a muscle or muscle tissue.

Progressive myopathies characterized by the presence of inclusion bodies on muscle biopsy. Sporadic and hereditary forms have been described. The sporadic form is an acquired, adult-onset inflammatory vacuolar myopathy affecting proximal and distal muscles. Familial forms usually begin in childhood and lack inflammatory changes. Both forms feature intracytoplasmic and intranuclear inclusions in muscle tissue. (Adams et al., Principles of Neurology, 6th ed, pp1409-10)

Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)

Inflammation of the extraocular muscle of the eye. It is characterized by swelling which can lead to ischemia, fibrosis, or ORBITAL PSEUDOTUMOR.

A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)

Experimental animal models for human AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM. They include GUILLAIN-BARRE SYNDROME (see NEURITIS, AUTOIMMUNE, EXPERIMENTAL); MYASTHENIA GRAVIS (see MYASTHENIA GRAVIS, AUTOIMMUNE, EXPERIMENTAL); and MULTIPLE SCLEROSIS (see ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL).

An enzyme that activates histidine with its specific transfer RNA. EC 6.1.1.21.

A nonspecific tumor-like inflammatory lesion in the ORBIT of the eye. It is usually composed of mature LYMPHOCYTES; PLASMA CELLS; MACROPHAGES; LEUKOCYTES with varying degrees of FIBROSIS. Orbital pseudotumors are often associated with inflammation of the extraocular muscles (ORBITAL MYOSITIS) or inflammation of the lacrimal glands (DACRYOADENITIS).

A genus of protozoa found in reptiles, birds, and mammals, including humans. This heteroxenous parasite produces muscle cysts in intermediate hosts such as domestic herbivores (cattle, sheep, pigs) and rodents. Final hosts are predators such as dogs, cats, and man.

A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.

A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)

Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.

Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.

The portion of the leg in humans and other animals found between the HIP and KNEE.

The flesh-eating bacterium: what's next? (1/580)

Since the 1980s, there has been a marked increase in the recognition and reporting of highly invasive group A streptococcal (GAS) infections associated with shock and organ failure, with or without necrotizing fasciitis. Such dramatic cases have been defined as streptococcal toxic shock syndrome (StrepTSS). Strains of GAS isolated from patients with invasive disease have been predominantly M types 1 and 3, which produce either pyrogenic exotoxin A or B or both. The clinical and demographic features of streptococcal bacteremia, myositis, and necrotizing fasciitis are presented and compared with those of StrepTSS. Current concepts in the pathogenesis of invasive streptococcal infection will be presented, with emphasis on the interaction between GAS virulence factors and host defense mechanisms. Finally, new concepts in the treatment of StrepTSS will be discussed. (+info)

Biodistribution, radiation dosimetry and pharmacokinetics of 111In-antimyosin in idiopathic inflammatory myopathies. (2/580)

In view of the established role of 111In-antimyosin in the detection of heart muscle pathology, radiation dose estimates were made for this substance. Biodistribution and biokinetic data were obtained from our studies, which failed to show abnormal uptake of 111In-antimyosin in localized sites of skeletal muscle involvement in patients with idiopathic inflammatory myopathies. METHODS: After intravenous administration of 74 MBq (2 mCi) 111In-antimyosin, gamma camera scintigraphy was performed in 12 adult patients with inflammatory muscle disease and in 2 control patients. Six whole-body scans were performed over 72 h, and uptake of 111In-antimyosin in organs was quantified using an attenuation-corrected conjugate counting method. Residence times in source organs were used with MIRDOSE software to obtain radiation dose estimates. Pharmacokinetic parameters were derived from serial whole-blood and plasma 111In concentrations. RESULTS: The tracer cleared slowly from the circulation, and highest organ uptakes were found in the marrow and liver; kidneys showed the highest concentrations. Uptake was also evident in spleen, the facial image and male genitalia. CONCLUSION: For a typical administered activity of 74 MBq 111In-antimyosin, the kidneys receive the highest dose (58 mSv), and the effective dose is 11 mSv. Radioactivity was cleared from plasma at an average rate of 136 mL/h, and the mean steady-state distribution was approximately 5 L plasma. (+info)

Polymyositis with biological false-positive serological test for syphilis. A case report. (3/580)

A young female came to the clinic with polymyositis and a biological false-positive serological test for syphilis (BFP reaction). Polymyositis, like other connective-tissue diseases, should be considered in the study of BFP reactors. (+info)

Autoantibodies in primary Sjogren's syndrome are directed against proteasomal subunits of the alpha and beta type. (4/580)

OBJECTIVE: The proteasome subunit HC9 (alpha3) has recently been identified as a major target of the humoral autoimmune response in patients with autoimmune myositis and systemic lupus erythematosus. Since B cell hyperreactivity is a common feature of systemic autoimmune diseases, patients with primary Sjogren's syndrome (SS) and other control groups were investigated to evaluate the significance of autoantibodies against the proteasome. METHODS: Analyses of autoantibodies directed against the 20S proteasome were performed using enzyme-linked immunosorbent assay, immunoblot, and 2-dimensional electrophoresis. Forty-three patients with primary SS, 47 patients with rheumatoid arthritis including 9 with secondary SS, 19 patients with gastrointestinal tumors, and 80 healthy controls were tested for antiproteasome antibodies. RESULTS: Antiproteasome antibodies were detected in 39% of patients (17 of 43) with primary SS. In contrast, only 1 of 47 patients with rheumatoid arthritis showed positive reactivity (P < 0.001). Serum samples from 19 tumor patients (P < 0.003) and 80 healthy controls (P < 0.001) were serologically negative. Moreover, immunoblotting and 2-dimensional analysis of the antiproteasome response revealed a polyspecific recognition pattern in 7 patients with primary SS. Different proteasomal subunits of the alpha and beta type, including subunits that carried the proteolytic active sites, were recognized by the patients' sera. CONCLUSION: The humoral antiproteasome response in primary SS, in contrast to its secondary form, is characterized by an extensive recognition pattern of several subunits, indicating a polyspecific B cell activation against the 20S proteasome. Moreover, proteolytically active beta-type subunits, which are important for the generation of major histocompatibility complex class I-restricted antigens, appear to be targets of the autoimmune response. The data indicate that the proteasome itself may stand on a cross point of pathways that links mechanisms of the immune defense with features of systemic autoimmunity. (+info)

Clinical and laboratory manifestations of systemic sclerosis (scleroderma) in Black South Africans. (5/580)

A retrospective study of systemic sclerosis (SSc) in Blacks attending a tertiary hospital on the Witwatersrand, South Africa, was undertaken. The female:male ratio of the 63 patients was 4.6:1 and the mean age of onset of SSc was 36.1 yr. Four of the 11 males were ex-goldminers and nine females resided close to goldmines. Forty-one patients had diffuse cutaneous SSc (dcSSc), 18 had limited cutaneous SSc (lcSSc) and four were unclassified. Overall, 56% had pulmonary fibrosis, 37% had myositis and 98% were antinuclear antibody (ANA) positive, with a notable absence of anti-centromere antibodies. Subset comparisons showed myositis and a reduced forced vital capacity to be significantly more common with dcSSc than lcSSc. The only significant sex differences were that arthralgia/arthritis was more common in women, while calcinosis occurred more frequently in men. Seven of the eight known deaths occurred in patients with dcSSc. These findings, particularly the age of disease onset, predominance of the dcSSc subset, inflammatory features of myositis and a raised erythrocyte sedimentation rate, and absence of anti-centromere antibodies, are similar to those reported previously in African-Americans. (+info)

Inosine and N1-methylinosine within a synthetic oligomer mimicking the anticodon loop of human tRNA(Ala) are major epitopes for anti-PL-12 myositis autoantibodies. (6/580)

Sera of some patients afflicted with the inflammatory disease myositis contain antibodies of the anti-PL-12 type. A fraction of these polyclonal autoantibodies specifically precipitates the fully matured human tRNA(Ala) bearing the anticodon IGC (PL-12 antigen). Earlier work (Bunn & Mathews, 1987, Science 238:116-119) had shown that the epitopes are located entirely within the anticodon stem-loop of the tRNA(Ala). Here we demonstrate that human anti-tRNA(Ala) autoantibodies immunoprecipitate a synthetic polyribonucleotide containing inosine (I) and N1-methylinosine (m1I) separated by 2 nt as in the anticodon stem-loop of human tRNA(Ala). The shortest polyribonucleotide that can be immunoprecipitated corresponds to the pentanucleotide IpGpCpm1IpUp, which corresponds to part of the anticodon loop of human tRNA(Ala) and lacks the stem-loop structure. The efficiency of immunoprecipitation was about four times greater with longer polyribonucleotides capable of forming a stem-loop structure, and was abolished by altering the relative positions of I and m1I within the synthetic polynucleotide. Synthetic oligodeoxyribonucleotide analogs of the tRNA(Ala) stem-loop, containing the sequence dIpdGdCdm1Ip, are not antigenic. Our results show that human anti-tRNA(Ala) autoantibodies selectively recognize chemical details of modified nucleotides (the 6-keto group of inosine-34 and the 6-keto group and the N1-methyl groups of N1-methylinosine-37) within an anticodon loop structure of a tRNA molecule. We also describe the chemical synthesis of the phosphoramidite derivatives corresponding to N1-methylinosine and N1-methyl-2'-deoxyinosine for use in the automatic chemical synthesis of oligonucleotides containing N1-methylinosine and N1-methyl-2'-deoxyinosine. (+info)

Staging of the baboon response to group A streptococci administered intramuscularly: a descriptive study of the clinical symptoms and clinical chemical response patterns. (7/580)

Group A streptococcal infections, ranging from necrotizing fasciitis and myositis to toxic shock syndrome, have increased over the last 10 years. We developed the first primate model of necrotizing fasciitis and myositis. Thirteen baboons were inoculated intramuscularly with group A streptococci (GAS). Eleven animals survived for > or = 11 days before sacrifice, and two animals died within 2 days. The site of inoculation of the survivors exhibited an intense neutrophilic influx (stage I), followed by a lymphoplasmacytic influx (stages II and III). This was accompanied by the appearance of markers of an acute and then a chronic systemic inflammatory response. In contrast, the site of inoculation of the two nonsurvivors exhibited intravascular aggregates of neutrophils at its margin with no influx of neutrophils and with extensive bacterial colonization. We conclude that GAS inoculation induces a local and systemic acute neutrophilia followed by a chronic lymphoplasmacytic response; failure, initially, of neutrophilic influx into the site of inoculation predisposes to systemic GAS sepsis and death; and this three-stage primate model approximates the human disease. (+info)

Pentazocine-induced fibromyositis and contracture. (8/580)

We report a case of myopathy, accompanied by widespread contractures predominantly involving the elbow and knee joints, following long-standing pentazocine abuse. (+info)

Myositis is a medical term that refers to inflammation of the muscle tissue. This condition can cause various symptoms, including muscle weakness, pain, swelling, and stiffness. There are several types of myositis, such as polymyositis, dermatomyositis, and inclusion body myositis, which have different causes and characteristics.

Polymyositis is a type of myositis that affects multiple muscle groups, particularly those close to the trunk of the body. Dermatomyositis is characterized by muscle inflammation as well as a skin rash. Inclusion body myositis is a less common form of myositis that typically affects older adults and can cause both muscle weakness and wasting.

The causes of myositis vary depending on the type, but they can include autoimmune disorders, infections, medications, and other medical conditions. Treatment for myositis may involve medication to reduce inflammation, physical therapy to maintain muscle strength and flexibility, and lifestyle changes to manage symptoms and prevent complications.

Inclusion body myositis (IBM) is a rare inflammatory muscle disease characterized by progressive weakness and wasting (atrophy) of skeletal muscles. The term "inclusion body" refers to the presence of abnormal protein accumulations within muscle fibers, which are observed under a microscope during muscle biopsy. These inclusions are primarily composed of aggregated forms of amyloid-β and tau proteins, similar to those found in neurodegenerative disorders like Alzheimer's disease.

IBM typically affects individuals over 50 years old, and it is more common in men than women. The disease usually starts with weakness in the wrist and finger flexors, making it difficult to perform tasks such as gripping, buttoning shirts, or lifting objects. Over time, the weakness spreads to other muscle groups, including the thigh muscles (quadriceps), resulting in difficulty climbing stairs or rising from a seated position.

The exact cause of inclusion body myositis remains unclear; however, both immune-mediated and degenerative mechanisms are believed to contribute to its pathogenesis. Currently, there is no cure for IBM, and treatment options are primarily aimed at managing symptoms and improving quality of life. Immunosuppressive medications may be used to target the inflammatory component of the disease; however, their efficacy varies among patients. Physical therapy and exercise programs can help maintain muscle strength and function as much as possible.

Polymyositis is defined as a rare inflammatory disorder that causes muscle weakness and inflammation (swelling) of the muscles. It primarily affects the skeletal muscles, which are the muscles responsible for voluntary movements such as walking, talking, and swallowing. The onset of polymyositis can occur at any age but is most commonly seen in adults between 31 to 60 years old, with women being slightly more affected than men.

The exact cause of polymyositis remains unknown; however, it is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks its own muscle tissue. Certain factors such as genetics, viral infections, and exposure to certain drugs may contribute to the development of this condition.

Polymyositis can cause various symptoms, including:
- Progressive muscle weakness and wasting, particularly affecting the proximal muscles (those closest to the trunk of the body) such as the hips, thighs, shoulders, and upper arms.
- Difficulty climbing stairs, lifting objects, or rising from a seated position.
- Fatigue and stiffness, especially after periods of inactivity.
- Joint pain and swelling.
- Difficulty swallowing or speaking.
- Shortness of breath due to weakened respiratory muscles.

Diagnosis of polymyositis typically involves a combination of medical history, physical examination, laboratory tests, electromyography (EMG), and muscle biopsy. Treatment usually includes medications such as corticosteroids and immunosuppressants to reduce inflammation and control the immune response. Physical therapy may also be recommended to help maintain muscle strength and flexibility.

If left untreated, polymyositis can lead to significant disability and complications, including respiratory failure, malnutrition, and cardiovascular disease. Early diagnosis and treatment are crucial for improving outcomes and preventing long-term complications.

Orbital myositis is a medical condition characterized by inflammation of the extraocular muscles, which are the muscles responsible for eye movement. These muscles are located within the orbit, the bony cavity that contains and protects the eye. Orbital myositis can cause symptoms such as painful eye movements, double vision, redness, swelling, and decreased visual acuity.

The condition is often associated with other systemic inflammatory or autoimmune disorders, such as rheumatoid arthritis, granulomatosis with polyangiitis (GPA), and sarcoidosis. However, it can also occur as an isolated phenomenon, known as idiopathic orbital myositis.

Diagnosis of orbital myositis typically involves a combination of clinical examination, imaging studies such as MRI or CT scans, and blood tests to evaluate for underlying systemic conditions. Treatment usually includes corticosteroids to reduce inflammation and alleviate symptoms, as well as addressing any underlying systemic disorders if present.

Dermatomyositis is a medical condition characterized by inflammation and weakness in the muscles and skin. It is a type of inflammatory myopathy, which means that it causes muscle inflammation and damage. Dermatomyositis is often associated with a distinctive rash that affects the skin around the eyes, nose, mouth, fingers, and toes.

The symptoms of dermatomyositis can include:

* Progressive muscle weakness, particularly in the hips, thighs, shoulders, and neck
* Fatigue
* Difficulty swallowing or speaking
* Skin rash, which may be pink or purple and is often accompanied by itching
* Muscle pain and tenderness
* Joint pain and swelling
* Raynaud's phenomenon, a condition that affects blood flow to the fingers and toes

The exact cause of dermatomyositis is not known, but it is believed to be related to an autoimmune response in which the body's immune system mistakenly attacks healthy tissue. Treatment for dermatomyositis typically involves medications to reduce inflammation and suppress the immune system, as well as physical therapy to help maintain muscle strength and function.

A nervous system autoimmune disease, experimental, refers to a type of disorder in which the immune system mistakenly attacks healthy nerves or tissues in the nervous system. This category includes conditions that are currently being researched and have not yet been fully proven or accepted by the medical community as definitive diseases.

In an autoimmune disease, the body's immune system produces antibodies and activates immune cells (such as T-cells) to attack and destroy foreign substances, such as bacteria and viruses. However, in an experimental nervous system autoimmune disease, the immune system mistakenly identifies normal nerves or nerve tissues as harmful and attacks them. This can lead to damage or destruction of the nerves, resulting in various neurological symptoms.

Examples of experimental nervous system autoimmune diseases may include conditions such as MOG antibody-associated disease (MOGAD) or anti-NMDA receptor encephalitis, which are still being studied and have not yet been fully recognized by the medical community. It is important to note that while these conditions are considered experimental, they can still cause significant harm and should be treated with appropriate medical interventions.

Histidine-tRNA ligase is an enzyme involved in the process of protein synthesis, specifically during the step of translation. Its primary function is to catalyze the attachment of the amino acid histidine to its corresponding transfer RNA (tRNA) molecule. This enzyme does this by forming a ester bond between the carboxyl group of histidine and the 3'-hydroxyl group of the tRNA, creating a charged histidine-tRNA complex.

The histidine-tRNA ligase enzyme plays a crucial role in maintaining the accuracy of protein synthesis, as it ensures that only the correct amino acid is attached to its specific tRNA. This helps to prevent errors in the genetic code and contributes to the proper folding and functioning of proteins.

The systematic name for this enzyme is "histidine:tRNA(His) ligase (AMP-forming)" and it belongs to the family of ligases, specifically the aminoacyl-tRNA ligases. The gene that encodes this enzyme in humans is known as HARS1 (Histidyl-tRNA Synthetase 1). Defects or mutations in this gene can lead to various genetic disorders, such as histidinemia and Charcot-Marie-Tooth disease.

Orbital pseudotumor, also known as orbital inflammatory syndrome or idiopathic orbital inflammation, is a non-specific term used to describe a group of conditions characterized by inflammation in the orbit (the bony cavity surrounding the eye) without any identifiable cause. It is not a true tumor, but rather an inflammatory reaction that can mimic the symptoms and signs of a tumor.

The condition can affect people of any age, although it is more common in middle-aged adults. The exact cause of orbital pseudotumor is unknown, but it is believed to be related to an abnormal immune response or inflammation triggered by various factors such as infections, trauma, or autoimmune disorders.

Symptoms of orbital pseudotumor may include eye pain, redness, swelling, protrusion of the eyeball (proptosis), double vision, and decreased vision. Diagnostic tests such as imaging studies (CT or MRI scans) and biopsy may be used to rule out other causes of orbital inflammation. Treatment typically involves corticosteroids to reduce inflammation, although other immunosuppressive medications may be necessary in severe cases. In some cases, the condition may resolve on its own without treatment.

Sarcocystis is a genus of intracellular parasitic protozoa that belongs to the phylum Apicomplexa. These microscopic organisms are known to infect both animals and humans, causing a variety of symptoms depending on the specific species involved and the immune status of the host.

Sarcocystis spp. have a complex life cycle involving two hosts: an intermediate host, which is typically a herbivorous animal, and a definitive host, which is usually a carnivorous or omnivorous animal. The parasites form cysts, known as sarcocysts, in the muscles of the intermediate host, which are then ingested by the definitive host during feeding.

In humans, Sarcocystis spp. can cause two main types of infections: intestinal and muscular. Intestinal infection occurs when humans accidentally ingest undercooked or raw meat containing Sarcocystis cysts. The parasites then invade the human's intestinal wall, causing symptoms such as diarrhea, abdominal pain, and fever.

Muscular infection, on the other hand, is caused by the ingestion of water or food contaminated with sporocysts shed in the feces of infected definitive hosts. This type of infection is relatively rare in humans and typically causes mild symptoms such as muscle pain, weakness, and fever.

It's worth noting that while Sarcocystis spp. can cause illness in humans, they are not usually considered a significant public health concern. Proper cooking of meat and good hygiene practices can help prevent infection with these parasites.

Skeletal muscle, also known as striated or voluntary muscle, is a type of muscle that is attached to bones by tendons or aponeuroses and functions to produce movements and support the posture of the body. It is composed of long, multinucleated fibers that are arranged in parallel bundles and are characterized by alternating light and dark bands, giving them a striped appearance under a microscope. Skeletal muscle is under voluntary control, meaning that it is consciously activated through signals from the nervous system. It is responsible for activities such as walking, running, jumping, and lifting objects.

Muscle weakness is a condition in which muscles cannot develop the expected level of physical force or power. This results in reduced muscle function and can be caused by various factors, including nerve damage, muscle diseases, or hormonal imbalances. Muscle weakness may manifest as difficulty lifting objects, maintaining posture, or performing daily activities. It is essential to consult a healthcare professional for proper diagnosis and treatment of muscle weakness.

Muscular diseases, also known as myopathies, refer to a group of conditions that affect the functionality and health of muscle tissue. These diseases can be inherited or acquired and may result from inflammation, infection, injury, or degenerative processes. They can cause symptoms such as weakness, stiffness, cramping, spasms, wasting, and loss of muscle function.

Examples of muscular diseases include:

1. Duchenne Muscular Dystrophy (DMD): A genetic disorder that results in progressive muscle weakness and degeneration due to a lack of dystrophin protein.
2. Myasthenia Gravis: An autoimmune disease that causes muscle weakness and fatigue, typically affecting the eyes and face, throat, and limbs.
3. Inclusion Body Myositis (IBM): A progressive muscle disorder characterized by muscle inflammation and wasting, typically affecting older adults.
4. Polymyositis: An inflammatory myopathy that causes muscle weakness and inflammation throughout the body.
5. Metabolic Myopathies: A group of inherited disorders that affect muscle metabolism, leading to exercise intolerance, muscle weakness, and other symptoms.
6. Muscular Dystonias: Involuntary muscle contractions and spasms that can cause abnormal postures or movements.

It is important to note that muscular diseases can have a significant impact on an individual's quality of life, mobility, and overall health. Proper diagnosis and treatment are crucial for managing symptoms and improving outcomes.

Autoantibodies are defined as antibodies that are produced by the immune system and target the body's own cells, tissues, or organs. These antibodies mistakenly identify certain proteins or molecules in the body as foreign invaders and attack them, leading to an autoimmune response. Autoantibodies can be found in various autoimmune diseases such as rheumatoid arthritis, lupus, and thyroiditis. The presence of autoantibodies can also be used as a diagnostic marker for certain conditions.

In the context of human anatomy, the thigh is the part of the lower limb that extends from the hip to the knee. It is the upper and largest portion of the leg and is primarily composed of the femur bone, which is the longest and strongest bone in the human body, as well as several muscles including the quadriceps femoris (front thigh), hamstrings (back thigh), and adductors (inner thigh). The major blood vessels and nerves that supply the lower limb also pass through the thigh.

For myositis caused by a bacterial infection, antibiotics can be used. For myositis caused by a medication, it is important to ... Treatment for myositis depends on the underlying cause. For myositis that is caused by a viral infection, no treatment is ... Viruses, such as COVID-19, are also shown to be a rare cause of myositis. Benign acute childhood myositis has been described in ... Medicines - A variety of different medicines can cause myositis. One of the most common drug types that can cause myositis is ...

https://en.wikipedia.org/wiki/Myositis

Inclusion Body Myositis ,or IBM, is one of many muscle diseases known as inflammatory myopathies,. *900 Words ... Inclusion Body Myositis ,or IBM, is one of many muscle diseases known as inflammatory myopathies, which causes slowly ... Inclusion Body Myositis ,or IBM, is one of many muscle diseases known as inflammatory myopathies,. ...

https://www.bartleby.com/topics/inclusion-body-myositis

Click on Myositis and Myopathy if you want to hear the full episode. Until next time. Ive been Dr Matthew Frank Watto. ... But I did not have nearly the framework that I do now after hearing the episode Myositis and Myopathy with Dr Lisa Christopher- ... The ANA is often positive, but anemia is not a common finding for some reason in myositis, and inflammatory markers are often ... You can see isolated weakness, or weakness with mild pain, but myositis doesnt present as an isolated pain syndrome. That is ...

https://www.medscape.com/viewarticle/984401

Infectious myositis is an acute, subacute, or chronic infection of skeletal muscle. Once considered a tropical disease, it is ... encoded search term (Infectious Myositis) and Infectious Myositis What to Read Next on Medscape ... Infectious Myositis. Updated: Jan 13, 2018 * Author: Mohammed J Zafar, MD, FAAN, FACP, FASN; Chief Editor: Niranjan N Singh, ... Lyme myositis may result from direct invasion of muscle by the spirochete Borrelia burgdorferi or by autoimmune mechanisms. [3 ...

https://emedicine.medscape.com/article/1168167-overview

February 18, 2005: The Rituximab In Myositis (RIM) Study * February 1, 2005: IMACS trial outcomes data repository in ... Rider LG, Giannini EH, Brunner HI, Ruperto N, James-Newton L, Reed AM, Lachenbruch PA, Miller FW; International Myositis ... April 14, 2006: IMACS Joins the International Myositis Classification Criteria Project * October 3, 2005: IMACS Annual Meeting ... International Consensus On Preliminary Definitions of Improvement for Adult and Juvenile Myositis, Arthritis Rheum., 2004 Jul, ...

https://www.niehs.nih.gov/research/resources/imacs/news_main/news_item04jul01/index.cfm

Myositis ossificans is a condition where bone tissue forms inside muscle or other soft tissue after an injury. Learn about the ... Myositis ossificans is often caused by a single traumatic injury.. Myositis ossificans usually occurs where a person has ... Very rarely, myositis ossificans can occur after a severe muscle strain.. Regardless of the cause, myositis ossificans happens ... An MRI may help diagnose myositis ossificans.. Before diagnosing myositis ossificans, a doctor will ask about what happened, ...

https://www.medicalnewstoday.com/articles/320718?utm_source=ReadNext

Myositis is a chronic, progressive, and inflammatory disease that causes muscle weakness and skin rashes. Its a rare disease ... Inclusion-body myositis. Inclusion-body myositis (IBM) is the only myositis which occurs more commonly in men than in women. ... Myositis can affect both children and adults. With the exception of one type of myositis, women are more likely to be affected ... www.myositis.org/learn-about-myositis/types-of-myositis/juvenile-dermatomyositis. *. Myositis. (n.d.).. http://www.arthritis. ...

https://www.healthline.com/health/myositis?utm_source=ReadNext

Learn more about the symptoms, diagnosis, and treatment of myositis at UPMC. ... Myositis refers to an inflammation of the muscles that allow you to move. ... Myositis can cause skin issues, too.. Is myositis a serious illness?. Yes. Myositis can cause health problems that can lead to ... What Are the Risk Factors of Myositis?. There are risk factors that increase the odds of getting myositis:. *Age. Myositis can ...

https://www.upmc.com/services/rheumatology/conditions/myositis

Check out a timeline of key events for The Myositis Association, from our founding in 1993 to the present. ... TMA revises Myositis 101, a lay persons guide to myositis.. *TMA Executive Director Bob Goldberg, retires after leading the ... TMA switches Myositis Awareness Day (September 21) to Myositis Awareness Month (May) to increase opportunities for raising ... United States Congress grants TMA an appropriation of $170,000 to fund a myositis patient registry to better track myositis ...

https://www.myositis.org/about-tma/history/

... Curr Opin Neurol. 2014 Oct;27(5):591-8. doi: 10.1097/WCO. ... diagnosis and treatment of sporadic inclusion body myositis (IBM). ...

https://pubmed.ncbi.nlm.nih.gov/25159931/

Information on Masticatory muscle myositis in dogs and how it can be treated. ... Masticatory muscle myositis in dogs. Masticatory Muscle Myositis (MMM) and Extraocular Myositis (EOM) in dogs. Osteoarthritis ... Masticatory muscle myositis is known under several different names, including atrophic myositis and eosinophilic myositis. ... Masticatory muscle myositis symptoms in dogs. A dog with acute Masticatory muscle myositis can show symptoms such as swollen ...

http://www.aquaticcommunity.com/dog/health/muscles/mmm.php

... research and support to the myositis community. Find resources, learn about treatments and connect with others like you. ... Myositis 101 for Patients. The Myositis 101 for patients videos by Dr. Rohit Aggarwal, Co-Director of Myositis Center of ... May is National Myositis Awareness Month! Celebrate with us by learning how to educate your community about myositis. With our ... What is Myositis?. Myositis is a muscle-wasting disease that results in fatigue and reduced strength. ...

https://www.myositis.org/

Field AS, Paik JY, Stark D, Qiu MR, Morey A, Plit ML, Myositis due to the microsporidian Anncaliia (Brachiola) algerae in a ... Coyle CM, Weiss LM, Rhodes LV III, Cali A, Takvorian PM, Brown DF, Fatal myositis due to the microsporidian Brachiola algerae, ... Field AS, Marriott DJ, Milliken ST, Brew BJ, Canning EU, Kench JG, Myositis associated with a newly described microsporidian, ... Myositis due to Pleistophora (Microsporidia) in a patient with AIDS. Clin Infect Dis. 1993;16:15-21. DOIPubMedGoogle Scholar ...

https://wwwnc.cdc.gov/eid/article/20/2/13-1126_article

We use cookies to personalize content and ads, provide social media features, and analyze our traffic. See our cookie policy.. ...

https://www.antechdiagnostics.com/test/masticatory-muscle-myositis/

Myositis. www.tabers.com/tabersonline/view/Tabers-Dictionary/729759/all/myositis. Accessed April 29, 2021. ... Myositis is an inflammation or swelling of the muscles. It is most often caused by injury, infection, medicines, or an ...

https://www.limamemorial.org/health-library/HIE%20Multimedia/1/001245

What is the association between exposure to statin medications and histologically confirmed idiopathic inflammatory myositis? ... While there is a recently described association of statin use with an immune-mediated necrotizing myositis through the ... Results were similar even when excluding necrotizing myositis, which already has a known association with statin use, which ... There is mounting evidence of an infrequent side effect known as idiopathic inflammatory myositis (IIM), that requires ...

https://community.the-hospitalist.org/hospitalist/article/198678/endocrinology?channel=206

Find out all the latest news from Myositis UK on our blog. ... Myositis UK recently adopted a new process for reviewing grant ... Myositis UK is a small national charity providing information to those affected by myositis and funding research to improve ... The Covid-19 Global Rheumatology Alliance has a new patient survey which members of Myositis UK are encouraged to take part in ... Myositis UK members are invited to attend a virtual thesis seminar on 16 September at 6PM BST (1pm EDT) with Kyla Britson. ...

https://www.myositis.org.uk/news/

Myositis is a rare inflammatory muscle disease that often goes undiagnosed or misdiagnosed. An estimated 75,000 Americans ... TMAs Medical Advisory Board is made up of 23 of the worlds leading myositis researchers from the NIH, the Myositis Center at ... Myositis is a rare inflammatory muscle disease that often goes undiagnosed or misdiagnosed. An estimated 75,000 Americans ... A new analysis released by The Myositis Association (TMA) shows that nonwhite women are twice as likely to die than others with ...

https://www.mlo-online.com/management/article/21078850/may-is-myositis-awareness-month

098 Developing new therapeutic strategies for inclusion body myositis. Journal of Neurology, Neurosurgery & Psychiatry 2012;83: ...

https://jnnp.bmj.com/content/83/3/e1.47.citation-tools

Articles tagged with "myositis-specific antibodies". Myositis-Specific Antibodies Identified. Mithu Maheswaranathan, MD, & Lisa ... inclusion body myositis, and 8) overlap myositis.1 These categories help classify the myopathies based on clinical and ...

https://www.the-rheumatologist.org/tag/myositis-specific-antibodies/

PhysioAdvisor offers detailed physiotherapy information on myositis ossificans including: causes, symptoms, diagnosis, ... This condition is known as myositis ossificans.. Causes of myositis ossificans. Myositis ossificans is a rare condition that ... What is myositis ossificans?. Myositis ossificans is an uncommon condition that may occur following a thigh contusion (bruised ... Treatment for myositis ossificans. The best strategy to manage this condition is to prevent its occurrence. Once myositis ...

https://physioadvisor.com.au/injuries/thigh/myositis-ossificans

Anncaliia algerae Microsporidial Myositis Cite CITE. Title : Anncaliia algerae Microsporidial Myositis Personal Author(s) : ... 2014). Anncaliia algerae Microsporidial Myositis. 20(2). Watts, Matthew R. et al. "Anncaliia algerae Microsporidial Myositis" ... Microsporidian Myositis in Immunosuppressed Patient" 17, no. 9 (2011). Choudhary, Maria M. et al. "Tubulinosema sp. ... Microsporidian Myositis in Immunosuppressed Patient Personal Author(s) : Choudhary, Maria M.;Metcalfe, Maureen G.;Arrambide, ...

https://stacks.cdc.gov/view/cdc/23678

A Primer on Imaging in Myositis. A Primer on Imaging in Myositis. November 9, 2022. • By Rochelle Castillo, MD, MS, Andro ... Myositis & the Heart: New Perspectives on the Pathogenesis & Management of Cardiac Involvement in Myositis. ... Myositis & the Heart: New Perspectives on the Pathogenesis & Management of Cardiac Involvement in Myositis ... Ultrasound has been gaining traction for diagnostic purposes especially in chronic myositis, such as inclusion body myositis ( ...

https://www.the-rheumatologist.org/article/a-primer-on-imaging-in-myositis/?singlepage=1&theme=print-friendly

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...

https://adc.bmj.com/content/24/117/71

Initial predictors for mortality previously reported in patients with myositis-associated ILD were used as variables and ... Initial predictors for mortality previously reported in patients with myositis-associated ILD were used as variables and ... Conclusion: We successfully developed a cluster model that stratified patients with myositis-associated ILD who were treated ... outcomes by a cluster analysis using a large-scale multicenter retrospective cohort of Japanese patients with myositis- ...

https://www.frontiersin.org/articles/10.3389/fmed.2022.883699/full

Myositis ossificans is a misnomer, although the term myositis ossificans circumscripta continues to be used to describe ... Myositis ossificans in children: a review. Eur J Orthop Surg Traumatol. 2017 May. 27 (4):491-502. [QxMD MEDLINE Link]. ... Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans). Updated: Aug 18, 2023 * Author: Robert J Pignolo, MD, ... Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) * Sections Pediatric Fibrodysplasia Ossificans ...

https://reference.medscape.com/article/1007104-overview

Myositis. Definition: An inflammatory process affecting the skeletal muscles. Causes include infections, injuries, and ... Synonyms (terms occurring on more labels are shown first): myositis, muscle inflammation More information: PubMed search and ...

http://sideeffects.embl.de/se/C0027121/pt

Myositis is a condition that causes inflammation in the muscles. The disease damages fibers of the muscle, making it difficult ... About Myositis. Myositis is a condition that causes inflammation in the muscles. The disease damages the fibers of the muscle ... Treatment of myositis varies according to the cause. Some types of myositis go away on their own, while others are chronic. ... What Causes Myositis?. Myositis can be caused by inflammatory conditions like lupus, scleroderma and rheumatoid arthritis. It ...

https://creakyjoints.org/education/myositis/

Myositis is a disorder in which the immune system attacks the muscles. It is hoped that this new treatment may help improve the ... It is hoped that efgartigimod may help improve the symptoms of myositis. ...

https://www.wesleyresearch.org.au/research-project/testing-treatments-to-improve-symptoms-of-myositis/

Durvalumab-induced myocarditis, myositis, and myasthenia gravis: a case report. Journal of medical case reports 2021 May 31;15; ...

https://www.pneumotox.com/effect/view/1261/durvalumab/8686/myopathy-myositis-polymyositis-see-also-under-xba

Injury - A mild form of myositis can occur with hard exercise. (wikipedia.org)
Dermatomyositis (DM) is the easiest form of myositis to diagnose due to the purple-red rashes in the shape of the heliotrope flower . (healthline.com)
Necrotizing myopathy is a more newly defined form of myositis with muscle weakness similar to that of dermatomyositis and polymyositis. (upmc.com)
In two recent studies we showed that anti-SRP autoantibodies are a marker of an aggressive immune-mediated necrotizing myopathy whereas anti-Mi-2 autoantibodies are not associated with a particular form of myositis. (ru.nl)
This is a progressive form of myositis, typically seen in older adults, which can result in severe muscle weakness and difficulty swallowing. (ameripharmaspecialty.com)
We suggest that myopathy, in the form of myositis, should be recognized as a potential side effect of gabapentin in the literature. (qscience.com)

The three main types of idiopathic myositis (known as inflammatory myopathies) that typically test positive for autoantibodies are dermatomyositis, polymyositis, and inclusion body myositis. (wikipedia.org)
The idiopathic inflammatory myopathies (IIM) encompass eight categories: 1) dermatomyositis (DM) in adults, 2) juvenile dermatomyositis, 3) amyopathic DM, 4) cancer-associated DM, 5) polymyositis, 6) immune-mediated necrotizing myopathy, 7) inclusion body myositis, and 8) overlap myositis.1 These categories help classify the myopathies based on clinical and histologic features. (the-rheumatologist.org)
To stratify patients with polymyositis/dermatomyositis-associated interstitial lung disease (ILD) who were initially treated with an intensive regimen consisting of high-dose corticosteroids, a calcineurin inhibitor, and intravenous cyclophosphamide (triple-combo therapy) into subgroups based on mortality outcomes by a cluster analysis using a large-scale multicenter retrospective cohort of Japanese patients with myositis-associated ILD (JAMI). (frontiersin.org)
These chronic forms affect approximately 1 in 100,000 people, and include polymyositis, dermatomyositis and inclusion body myositis. (creakyjoints.org)
Inflammatory myositis is a systemic autoimmune disease that has four forms: polymyositis, dermatomyositis, necrotizing autoimmune myositis and inclusion body myositis. (asterhospitals.in)
New onset and/or active myositis including polymyositis, dermatomyositis. (qld.gov.au)
Types of Myositis include dermatomyositis (DM), polymyositis (PM), juvenile myositis (JM), and inclusion-body myositis (IBM). (myositissupport.org)
Autoimmune myositis causes inflammation and weakness in the muscles (polymyositis) or in the skin and muscles (dermatomyositis). (msdmanuals.com)

The ANA is often positive, but anemia is not a common finding for some reason in myositis, and inflammatory markers are often normal in dermatomyositis. (medscape.com)
The Landman Family created the Myositis Empower Walk in 2019 in loving memory of Bob Landman who passed away due to a too-late diagnosis of dermatomyositis . (myositisempowerwalk.org)

Similar to the other forms of myositis, JM is characterized by muscle weakness and skin rashes. (healthline.com)
TMA begins work on publishing a book on juvenile forms of myositis with the help of medical experts and families of those with JM. (myositis.org)
TMA publishes "Myositis and You", comprehensive 466-page text addressing the entire spectrum of issues and challenges related to juvenile forms of myositis. (myositis.org)
Some of the chronic forms of myositis are idiopathic inflammatory myopathies, meaning their cause is unknown. (creakyjoints.org)
The ability to recognize these different forms of myositis is of importance because of differences in associated disorders, complications, treatment responses, and prognosis. (ru.nl)
IVIG is the only treatment that is found to be safe, effective, and well-tolerated in the treatment of various forms of myositis. (ameripharmaspecialty.com)
Some forms of Myositis are chronic and idiopathic, meaning the cause is unknown or not well understood. (myositissupport.org)

Symptoms of toxic myositis are similar to those of other types of myositis. (healthline.com)
What Are the Different Types of Myositis? (upmc.com)
Symptoms start more slowly than they do for other types of myositis. (upmc.com)
Some types of myositis go away on their own, while others are chronic. (creakyjoints.org)

Unlike other typical muscle strains or injuries, people with myositis ossificans may notice that their pain worsens with time instead of getting better. (medicalnewstoday.com)
Blood tests to look for elevated creatine kinase levels, signaling inflammation in the muscle tissue in people with myositis. (upmc.com)
Myositis Canada is a non-profit agency formed in 2015 by people with myositis who wanted an agency dedicated to improving the lives of people affected by myositis. (skinpatientalliance.ca)
Dr. Bhai's current research involves understanding why people with myositis experience exercise intolerance and fatigue, even when their disease is well-controlled. (csipharmacy.com)

As the result of a series of international consensus workshops, IMACS partially validated Preliminary Definitions of Improvement for Adult and Juvenile Myositis. (nih.gov)
The new Preliminary Definitions of Improvement are being recommended for use as outcome measures in all clinical trials and outcome studies of adult and juvenile myositis. (nih.gov)
International Consensus On Preliminary Definitions of Improvement for Adult and Juvenile Myositis, Arthritis Rheum. (nih.gov)
Juvenile myositis (JM) occurs in children under 18 . (healthline.com)
Conference offers activities for juvenile myositis (JM) parents, families, and patients. (myositis.org)
TMA sponsors first national conference solely for juvenile myositis in Washington, D.C. (myositis.org)
Juvenile Myositis (JM) is a rare autoimmune disease that primarily affects children and adolescents, causing inflammation of the muscles and tissues. (myositissupportgroup.org)
however, they could potentially point towards an underlying case of Juvenile Myositis. (myositissupportgroup.org)
One primary symptom characteristic of Juvenile Myositis is muscle weakness, which often begins gradually and worsens over time. (myositissupportgroup.org)
In addition to muscle weakness and skin rashes, other possible symptoms of Juvenile Myositis can include fatigue, joint pain or swelling, difficulty swallowing or breathing due to weakened muscles in the throat or lungs, fever, and weight loss. (myositissupportgroup.org)
Early diagnosis and treatment are crucial in managing Juvenile Myositis effectively. (myositissupportgroup.org)
It is important for parents and caregivers to provide emotional support for children diagnosed with Juvenile Myositis as they navigate through challenges and potential limitations imposed by the condition. (myositissupportgroup.org)
Connecting with support groups or organizations dedicated to Juvenile Myositis can also provide valuable resources, information, and a sense of community for affected individuals and their families. (myositissupportgroup.org)
Overall, while Juvenile Myositis poses significant challenges, early diagnosis, appropriate medical intervention, and ongoing supportive care can help improve outcomes and enhance the quality of life for those living with this rare autoimmune disease. (myositissupportgroup.org)
Frightened by these sudden changes, Emily's parents rush her to the hospital where she is diagnosed with juvenile myositis (JM). (myositissupportgroup.org)
Juvenile myositis encompasses a group of rare conditions characterized by chronic muscle inflammation. (myositissupportgroup.org)

Inclusion Body Myositis ,or IBM, is one of many muscle diseases known as inflammatory myopathies, which causes slowly progressing muscular atrophy and weakness(NINDS IBM ,2014,para 1). (bartleby.com)
Inclusion-body myositis (IBM) is the only myositis which occurs more commonly in men than in women. (healthline.com)
Inclusion body myositis is more common in older people. (upmc.com)
Myositis can start at any age, but inclusion body myositis is more common after age 50. (upmc.com)
But inclusion body myositis is more common in men. (upmc.com)
Harrisonburg entrepreneur and IBM patient Betty Curry organizes the Inclusion Body Myositis Association (IBMA). (myositis.org)
To describe new insights and developments in the pathogenesis, diagnosis and treatment of sporadic inclusion body myositis (IBM). (nih.gov)
In inclusion body myositis, which typically affects men more than women, weakness usually starts in the upper legs and later affects the upper arms and muscles farther away from the center of the body, such as the hand, wrist and lower legs. (creakyjoints.org)
Muscle atrophy is often prominent, and up to half of people with inclusion body myositis have trouble swallowing. (creakyjoints.org)
With inclusion body myositis, the muscles have an abnormal protein called amyloid, similar to the amyloid that forms in the brain in people with Alzheimer's disease, but the reason it forms is unknown. (creakyjoints.org)
The anti-Jo-1 autoantibody is generally not encountered in inclusion body myositis (IBM), and the presence of this autoantibody in serum of a patient suspected of myositis virtually rules out the diagnosis IBM. (ru.nl)
Our Myositis Research Group, led by Professor Merrilee Needham, has a longstanding dedication to the investigation of clinical, genetic and immunological aspects of the inflammatory myopathies, with a focus on Inclusion Body Myositis (IBM), the most common muscle disease associated with aging. (perroninstitute.org)
Sporadic inclusion body myositis ( sIBM ) is an inflammatory muscle disease , characterized by slowly progressive weakness and wasting of the distal and proximal muscles, most apparent in the muscles of the arms and legs . (wikidoc.org)
In sporadic inclusion body myositis [MY-oh-sigh-tis] muscle, two processes, one autoimmune and the other degenerative, appear to occur in the muscle cells in parallel. (wikidoc.org)
The degeneration aspect is characterized by the appearance of holes in the muscle (vacuoles), deposits of amyloid-related proteins within the cells and filamentous inclusions (hence the name inclusion body myositis) of abnormal proteins. (wikidoc.org)
Inclusion body myositis is a form of idiopathic inflammatory myositis (IIM)of unknown etiology. (rheumaknowledgy.com)
Inclusion body myositis has distinct differences from the more common forms of IIM, PM, and DM . (rheumaknowledgy.com)
Histopathologic analysis is the key differentiating feature between inclusion body myositis and other forms of IIM. (rheumaknowledgy.com)
Inclusion body myositis represents 15% to 30% of IIM cases, which have a prevalence of five to 10 per million population. (rheumaknowledgy.com)
In contrast to PM/DM, distal muscle weakness, and asymmetric involvement are more commonly seen in inclusion body myositis. (rheumaknowledgy.com)
Muscle enzymes (e.g., creatine kinase) are elevated in inclusion body myositis as they are in IIM but usually less so in inclusion body myositis (as much as 10 times normal) than in PM/DM (as much as 50 times normal). (rheumaknowledgy.com)
Nonetheless, muscle biopsy with electron microscopic analysis is required to make a diagnosis of inclusion body myositis. (rheumaknowledgy.com)
Often the diagnosis of inclusion body myositis is made when patients with presumed PM or DM either do not respond to steroid therapy or display atypical manifestations (e.g., asymmetry, distal muscle weakness, peripheral neuropathy). (rheumaknowledgy.com)
In such instances, inclusion body myositis should be suspected, and muscle biopsy repeated or reviewed with emphasis on electron microscopic findings. (rheumaknowledgy.com)
The differential diagnosis of inclusion body myositis includes other types of IIM as well as other endocrinologic, metabolic, infectious, and toxic etiologies (see Myopathy ). (rheumaknowledgy.com)
Diagnostic criteria for inclusion body myositis have been proposed but not validated (Table 19). (rheumaknowledgy.com)
However, because of the poor response to corticosteroid or immunosuppressive therapies, many physicians do not pursue aggressive or alternative therapies in patients with inclusion body myositis with little or no response to corticosteroids. (rheumaknowledgy.com)
Inclusion body myositis is a slowly progressive disorder, and patients are less likely to respond to therapy than those with other types of IIM. (rheumaknowledgy.com)
A prospective natural history study of inclusion body myositis: implications for clinical trials. (rheumaknowledgy.com)
Inclusion body myositis: analysis of 32 cases. (rheumaknowledgy.com)
Inclusion body myositis symptoms are due to muscle weakness, usually beginning in middle-age or later, and worsen gradually over several years. (cureibm.org)
Trouble standing up from a low chair or toilet is a typical inclusion body myositis symptom. (cureibm.org)
Weak grip is another early inclusion body myositis symptom. (cureibm.org)
Swallowing difficulty, known as dysphagia , eventually affects many patients, but is an uncommon early symptom of inclusion body myositis. (cureibm.org)
Sleep apnea may be common in inclusion body myositis patients. (cureibm.org)
There are rare reports of IBM patients with trouble breathing because of weak muscles, but the vast majority of inclusion body myositis patients do not have prominent respiratory symptoms. (cureibm.org)
It is important to remember that inclusion body myositis is a variable disease. (cureibm.org)
Join Cure IBM in the fight against Inclusion Body Myositis. (cureibm.org)
Inclusion body myositis is a separate disorder that can cause muscle weakness and wasting away of muscle, most commonly in the legs, hands, and feet. (msdmanuals.com)
Current status of clinical outcome measures in inclusion body myositis: a systematised review. (bvsalud.org)
Sporadic inclusion body myositis (IBM) is a debilitating idiopathic inflammatory myopathy (IIM) which affects hand function, ambulation , and swallowing . (bvsalud.org)

IBMA merges with the National Myositis Association (NMA), expands to include all forms of myopathies and changes its name to the Myositis Association of America (MAA). (myositis.org)
Myositis refers to a group of autoimmune disorders (inflammatory myopathies) characterised by muscle inflammation resulting in muscle weakness and disability. (perroninstitute.org)
Intravenous immunoglobulin (IVIG) therapy has emerged as a promising treatment for myositis, often collectively known as i diopathic inflammatory myopathies (IIMs). (ameripharmaspecialty.com)

Medicines - A variety of different medicines can cause myositis. (wikipedia.org)
One of the most common drug types that can cause myositis is statins. (wikipedia.org)
Other autoimmune diseases, such as systemic lupus erythematosus, can also cause myositis-like symptoms. (wikipedia.org)
Regardless of the cause, myositis ossificans happens when the body makes an error in the healing process. (medicalnewstoday.com)
Two other species of Anncaliia are reported to cause myositis in humans ( 9 ). (cdc.gov)

There are various tools that can be used to help diagnose myositis. (wikipedia.org)

Today we wanted to bring you some quick tips about diagnosing myositis and myopathy. (medscape.com)
But I did not have nearly the framework that I do now after hearing the episode Myositis and Myopathy with Dr Lisa Christopher-Stine. (medscape.com)
Masticatory muscle myositis is the most commonly occurring inflammatory myopathy in dogs. (aquaticcommunity.com)
A myopathy is a neuromuscular disease where the muscles fibres do not function as they should, and masticatory muscle myositis is one of many different forms of myopathy. (aquaticcommunity.com)
Myositis and rhabdomyolysis are the same forms of myopathy, with rhabdomyolysis being a more severe form of myopathy. (qscience.com)

Myositis is a rare disease that involves inflammation of the muscles. (wikipedia.org)
Myositis is a chronic, progressive inflammation of the muscles. (healthline.com)
The definition of myositis is inflammation of the muscles. (upmc.com)
Myositis is an inflammation of the muscles, which can be caused by injury, infection, reaction from certain medications, and even exercise. (myositissupport.org)

This allows a physician to look at the muscles' response to various electrical nerve signals and evaluate which muscles potentially have myositis. (wikipedia.org)
Most of the time, myositis ossificans occurs in the large muscles of the arms or the legs. (medicalnewstoday.com)
Myositis is thought to be an autoimmune condition that causes the body to attack the muscles. (healthline.com)
In a dog suffering from masticatory muscle myositis, the dog's own immune system attacks a special muscle protein that is only found in these masticatory muscles. (aquaticcommunity.com)
A dog with acute Masticatory muscle myositis can show symptoms such as swollen jaw muscles and drooling, and it can be painful for the dog to open up the mouth. (aquaticcommunity.com)
Chronic Masticatory muscle myositis causes jaw muscles atrophy and scars will form in the masticatory muscles. (aquaticcommunity.com)
Myositis is an inflammation or swelling of the muscles. (limamemorial.org)
Myositis is a condition that causes inflammation in the muscles. (creakyjoints.org)
Myositis is a disorder in which the immune system attacks the muscles. (wesleyresearch.org.au)
Some people are genetically susceptible to having inflammation in the muscles as a result of post-viral myositis. (theweek.in)
Myositis represents a group of rare autoimmune diseases that causes chronic inflammation and weakness in the muscles. (ameripharmaspecialty.com)

Myositis ossificans is a condition where bone tissue forms inside muscle or other soft tissue after an injury. (medicalnewstoday.com)
Myositis ossificans is a condition characterized by ossification within a muscle. (e-acfs.org)

The 4th Global Conference on Myositis (GCOM) has been postponed until 2022 due to the ongoing Covid-19 pandemic. (myositis.org.uk)

Muscle biopsies are the most reliable tests for diagnosing myositis. (wikipedia.org)

Experts differ in their opinions as to the exact cause of myositis. (healthline.com)

What is the association between exposure to statin medications and histologically confirmed idiopathic inflammatory myositis? (the-hospitalist.org)
There is mounting evidence of an infrequent side effect known as idiopathic inflammatory myositis (IIM), that requires immunosuppressive therapy rather than just discontinuation of the medication. (the-hospitalist.org)
There was a statistically significant association between statin use and the incidence of idiopathic inflammatory myositis, which suggests that this condition is a potential serious side effect of statin therapy. (the-hospitalist.org)
Association of statin exposure with histologically confirmed idiopathic inflammatory myositis in an Australian population. (the-hospitalist.org)

IMPORTANT NOTICE FOR MEMBERS If you wish to continue your free membership of Myositis UK, please ensure you return your membership update form by 5 April 2021. (myositis.org.uk)

With the exception of one type of myositis, women are more likely to be affected by this disease than men. (healthline.com)
DM is the easiest type of myositis to diagnose because it typically has a visible skin rash caused by inflammation of blood vessels under the skin. (skinpatientalliance.ca)

What is Masticatory muscle myositis? (aquaticcommunity.com)
Masticatory muscle myositis, commonly abbreviated MMM, is an inflammatory disease the affects the jaws of the dog. (aquaticcommunity.com)
Masticatory muscle myositis is known under several different names, including atrophic myositis and eosinophilic myositis. (aquaticcommunity.com)
Masticatory muscle myositis is chiefly a problem for large dog breeds, especially German Shepherds. (aquaticcommunity.com)
The most commonly used Masticatory muscle myositis treatment is to give the sick dog corticosteroids ( glucocorticoids ), e.g. (aquaticcommunity.com)
In some dogs, masticatory muscle myositis turns into a reoccurring problem. (aquaticcommunity.com)
Masticatory muscle myositis is sometimes mistaken for a retroorbital abcess and the veterinarian will then attempt to treat the problem with antibiotics. (aquaticcommunity.com)
Antibiotics can not be used to cure masticatory muscle Myositis. (aquaticcommunity.com)

It is hoped that efgartigimod may help improve the symptoms of myositis. (wesleyresearch.org.au)
As per double-blind and placebo-controlled trials , IVIG therapy has been found to be effective in managing the symptoms of myositis. (ameripharmaspecialty.com)
Swelling, muscle weakness, pain, and skin rashes are the most common symptoms of myositis. (ameripharmaspecialty.com)

Every year, around 7,000 people receive a diagnosis of myositis, and there are more than 50,000 individuals in the United States living with this condition. (ameripharmaspecialty.com)

For myositis that is caused by a viral infection, no treatment is typically needed. (wikipedia.org)
This also happened during Covid - once viral fever hits a person and recovers, there may be symptoms such as muscle weakness and muscle inflammation, and these are typically associated with myositis. (theweek.in)

Benign acute childhood myositis has been described in children after prodromal viral infections with different viral agents. (wikipedia.org)
Infectious myositis is an acute, subacute, or chronic infection of skeletal muscle. (medscape.com)
Acute viral myositis. (medscape.com)
Mild amount of muscle weakness is associated with viral fever but acute stage is related to myositis,' said Dr Sandeep Yadav, consultant rheumatologist, PD Hinduja Hospital in Mumbai. (theweek.in)
Sometimes when the pain is acute, we need to admit them because severe myositis can also lead to renal failure,' says Dr Baghel. (theweek.in)

A. algerae has caused severe myositis in patients taking immunosuppressive medication for rheumatoid arthritis or solid-organ transplantation ( 3 , 5 , 8 ). (cdc.gov)

Since the clinical course, response to treatment, and prognosis are highly variable among patients with myositis-associated ILD ( 3 , 5 ), the treatment regimen is decided based mainly on the progression speed and severity of ILD. (frontiersin.org)
MSAs have helped recognizing some specific clinical subtypes of myositis. (ru.nl)
As a neurology resident, he gravitated toward patients with neuromuscular challenges and did clinical fellowships with some of the country's most renowned myositis experts in Boston. (csipharmacy.com)
The center will also serve as a site for clinical trials-Dr. Bhai currently serves as site investigator for nine clinical trials-where those with myositis can participate in testing of new therapies and diagnostics. (csipharmacy.com)

TMA publishes special comprehensive issues of The OutLook that cover products for myositis patients and treatment options and developments. (myositis.org)
United States Congress grants TMA an appropriation of $170,000 to fund a myositis patient registry to better track myositis patients and treatments. (myositis.org)
A retrospective, population-based, case-control study was conducted that compared the incidence of histologically confirmed IIM identified from the South Australian Myositis Database in patients 40 years or older with known statin exposure (n = 221) against population-based controls obtained from the North West Adelaide Health Study. (the-hospitalist.org)
Initial predictors for mortality previously reported in patients with myositis-associated ILD were used as variables and included age, sex, disease duration, classification of myositis, requirement of supplemental oxygen, anti-aminoacyl tRNA synthetase (ARS) antibody, anti-melanoma differentiation-associated gene 5 (MDA5) antibody, and serum levels of C-reactive protein (CRP) and Krebs von den Lungen-6 (KL-6). (frontiersin.org)
We successfully developed a cluster model that stratified patients with myositis-associated ILD who were treated with initial triple-combo therapy into subgroups with different prognoses, although this model failed to identify a patient subgroup that showed survival benefits from triple-combo therapy over dual-combo therapy or monotherapy. (frontiersin.org)
The sera of about half of the patients with myositis contain autoantibodies that are specific for this group of diseases compared to other inflammatory connective tissue disorders. (ru.nl)
Borrelia burgdorferi myositis: report of eight patients. (medscape.com)
We are developing a myositis center where patients don't have to travel so far to get the care that they need and deserve," he says. (csipharmacy.com)
Myositis patients have muscle disease as well as systemic involvement," he says. (csipharmacy.com)
Moreover, various studies have shown that IVIG can lead to improvements in muscle strength, endurance, and overall physical function in patients with myositis. (ameripharmaspecialty.com)

In terms of treatment for myositis-associated ILD, systemic corticosteroid therapy is usually combined with immunosuppressive agents, such as azathioprine, cyclophosphamide, mycophenolate mofetil, methotrexate, cyclosporine, tacrolimus, and/or rituximab, although there is little evidence to support the efficacy of these individual agents ( 4 ). (frontiersin.org)

Doctors define myositis as a rare autoimmune disease. (upmc.com)

A more severe form of muscle injury, called rhabdomyolysis, is also associated with myositis. (wikipedia.org)
Certain autoantibodies (antibodies that target muscle cells) can also be found in the blood, which can indicate that myositis is caused by an autoimmune disease. (wikipedia.org)
Lyme myositis may result from direct invasion of muscle by the spirochete Borrelia burgdorferi or by autoimmune mechanisms. (medscape.com)
In humans, the parasite loses its flagellum and transforms into the amastigote form, which may enter muscle and multiply, resulting in myositis. (medscape.com)
Myositis ossificans usually occurs where a person has experienced a single traumatic injury, such as sustaining a hit while playing football or soccer that causes a deep muscle bruise. (medicalnewstoday.com)
Very rarely, myositis ossificans can occur after a severe muscle strain. (medicalnewstoday.com)
Treatments help to prevent muscle loss and heart, lung, and other problems myositis can cause. (upmc.com)
Myositis can cause problems in muscle groups and other symptoms throughout the body. (upmc.com)
Myositis is a rare inflammatory muscle disease that often goes undiagnosed or misdiagnosed. (mlo-online.com)
Myositis ossificans is an uncommon condition that may occur following a thigh contusion (bruised thigh) and is characterized by bone formation (calcification) in the muscle belly at the site of the bruise. (physioadvisor.com.au)
Discussion: This patient presents with classic findings of myositis tropicans (MT). MT is a disease most commonly encountered in the tropics, but there has been a steady rise in temperate regions.1, 2 It is characterized by skeletal muscle inflammation that leads to intramuscular abscess formation. (cmcedmasters.com)
Whether they're trying to learn how to perform muscle biopsies or exercise testing, or they want to see what myositis looks like in a patient, I want to help support that. (csipharmacy.com)
Most people should exercise, even those who have a muscle disease like myositis. (csipharmacy.com)
An autoimmune condition called Myositis occurs when the immune system inappropriately targets healthy muscle tissue. (seoandcontentservices.com)
Myositis , derived from the Greek words "myo" (muscle) and "itis" (inflammation), collectively defines a chronic and progressive inflammation of muscle. (ameripharmaspecialty.com)
Myositis is often classified as an autoimmune disorder, where the immune system mistakenly injures muscle tissues and causes muscle weakness. (ameripharmaspecialty.com)
This therapy has shown beneficial effects in managing myositis symptoms, modulating the immune response, reducing inflammation, and preventing further muscle damage. (ameripharmaspecialty.com)
Myositis Ossificans Traumatica in the Temporalis Muscle. (e-acfs.org)
Myositis ossificans of the temporalis muscle is a very rare case. (e-acfs.org)
These disorders result in muscle inflammation (myositis), disabling muscle weakness, and occasionally tenderness. (msdmanuals.com)
The symptoms of autoimmune myositis are similar for people of all ages, but the muscle inflammation often appears to develop more abruptly in children than in adults. (msdmanuals.com)

It can be difficult to diagnose myositis ossificans in the early stages with just an X-ray. (medicalnewstoday.com)
How Do You Diagnose Myositis? (upmc.com)

Myositis can occur at any age, but it is most commonly prevalent in adults between 30 and 60 years old. (ameripharmaspecialty.com)

Although there is no cure for myositis, certain immunosuppressive medications and corticosteroids are usually prescribed as a first-line treatment to manage the symptoms of this condition. (ameripharmaspecialty.com)

There are eight different types of antisynthetase antibodies relevant to Myositis that have been discovered to date. (myositis.org.au)
Blood tests can be used to identify the presence of Myositis-specific antisynthetase antibodies. (myositis.org.au)

Myositis ossificans occurs in people who participate in sport at all levels, from those who are playing just for fun through to highly competitive or professional athletes. (medicalnewstoday.com)
Myositis Ossificans is a reactive soft tissue bone-forming process that commonly occurs following a traumatic event to soft tissues. (orthobullets.com)
This article provides a comprehensive understanding of myositis, how it occurs, its types, and how intravenous immunoglobulin (IVIG) therapy can offer hope and relief to those suffering from this challenging condition. (ameripharmaspecialty.com)
Autoimmune myositis usually occurs in adults aged 40 to 60 or in children aged 5 to 15 years. (msdmanuals.com)

You can see isolated weakness, or weakness with mild pain, but myositis doesn't present as an isolated pain syndrome. (medscape.com)

Treatment for myositis depends on the underlying cause. (wikipedia.org)
There are a variety of treatment options available if myositis is caused by an autoimmune disease. (wikipedia.org)
Also, intravenous immunoglobulins (IVIg) have also been shown to be effective in the treatment of myositis caused by an autoimmune disease. (wikipedia.org)
Myositis can cause health problems that can lead to death without proper treatment. (upmc.com)
On Saturday, September 9, TMA hosts our annual Heroes in the Fight Awards Celebration, honoring the dedicated researchers and clinicians working hard to make progress in the care and treatment of myositis diseases, and celebrating the extraordinary resilience and strength of our patient community. (myositis.org)
Myositis UK is a small national charity providing information to those affected by myositis and funding research to improve diagnosis and treatment. (myositis.org.uk)
Treatment of myositis varies according to the cause. (creakyjoints.org)
And because exercise is such an important part of the treatment plan for those with myositis, once COVID restrictions are no longer a problem, Dr. Bhai wants to include an exercise program in the mix. (csipharmacy.com)

She gave some nice, broad definitions and features that I found extraordinarily helpful to frame the discussion, the main point being that the predominant concern in myositis is weakness. (medscape.com)

Viruses: Viruses implicated in the pathogenesis of myositis include HIV-1, human T lymphotrophic virus 1 (HTLV-1), influenza, coxsackieviruses, and echoviruses. (medscape.com)

Rhabdomyolysis can complicate influenza and, rarely, coxsackievirus myositis. (medscape.com)

A new analysis released by The Myositis Association (TMA) shows that nonwhite women are twice as likely to die than others with the disease, and they are four times more likely to die than white men with the disease. (mlo-online.com)
The most prevalent MSA, the anti-Jo-1 autoantibody, is associated with the anti-synthetase syndrome consisting of myositis, interstitial lung disease, arthritis, and Raynaud's phenomenon. (ru.nl)

Infection - The most common infectious cause of myositis is viral infections, such as the common cold. (wikipedia.org)
O'Neill DS, Baquis G, Moral L. Infectious myositis. (medscape.com)

Since the past few weeks, viral myositis is being most commonly observed in clinics and outpatient departments across state-run hospitals in Mumbai. (theweek.in)

A myositis diagnosis often involves a physical exam and tests. (upmc.com)
The MRI myositis protocol involves T1-weighted imaging (T1W) and fluid-sensitive T2W with fat suppression or short-tau inversion recovery (STIR) sequence in the axial and coronal planes. (the-rheumatologist.org)

Influenza myositis could be due to direct viral invasion or autoimmune response. (medscape.com)
So this essentially is post-viral myositis, that is myositis that happens after the viral fever has come and gone. (theweek.in)
Infections such as viral infection or exposure to certain medications (statin) and illegal drugs-like cocaine may trigger myositis in susceptible individuals. (ameripharmaspecialty.com)

The insect microsporidian Anncaliia algerae was first described in 2004 as a cause of fatal myositis in an immunosuppressed person from Pennsylvania, USA. (cdc.gov)
A. algerae has emerged as a cause of myositis, particularly in coastal Australia. (cdc.gov)
A. algerae myositis was first described in 2004 in a patient from Pennsylvania, USA, who had rheumatoid arthritis ( 3 ). (cdc.gov)

In a recent study we showed that these myositis specific autoantibodies (MSAs) are also specific for myositis as compared to other neuromuscular disorders. (ru.nl)

Spread the Word" campaign begins to increase recognition of myositis in health care and patient communities. (myositis.org)
U.S. Congress awards TMA $167,000 for the creation of a myositis patient registry. (myositis.org)
The Covid-19 Global Rheumatology Alliance has a new patient survey which members of Myositis UK are encouraged to take part in. (myositis.org.uk)
Give to support the work of Myositis Support and Understanding (MSU), an all-volunteer, patient-led nonprofit. (myositisempowerwalk.org)
We report a case of probable gabapentin-induced myositis in a patient with spinal cord injury who was on an increasing dose of gabapentin. (qscience.com)

For myositis caused by a bacterial infection, antibiotics can be used. (wikipedia.org)

Even though we still do not know the cause(s) of the myositis syndromes or the reason(s) for MSA formation, the MSAs have facilitated our thinking on the pathophysiology of myositis. (ru.nl)

All money raised goes to Myositis Support and Understanding (MSU) and is used to further the mission, to improve the lives of and empower those fighting myositis . (myositisempowerwalk.org)

These immunoglobulins help strengthen the immune system and can modulate the autoimmune response that leads to myositis. (ameripharmaspecialty.com)

There are also a variety of blood tests available that help in the diagnoses of myositis. (wikipedia.org)

Rarely, statin therapy can lead to myositis. (wikipedia.org)
While there is a recently described association of statin use with an immune-mediated necrotizing myositis through the formation of an autoantibody against HMG-CoA Reductase, this epidemiological study aimed to look at the incidence of statin use against all confirmed cases of IIM. (the-hospitalist.org)
Results were similar even when excluding necrotizing myositis, which already has a known association with statin use, which suggests that statin use could be associated with all types of IIM. (the-hospitalist.org)

Anatomy2

Organisms1

Diseases9

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

The flesh-eating bacterium: what's next? (1/580)

Biodistribution, radiation dosimetry and pharmacokinetics of 111In-antimyosin in idiopathic inflammatory myopathies. (2/580)

Polymyositis with biological false-positive serological test for syphilis. A case report. (3/580)

Autoantibodies in primary Sjogren's syndrome are directed against proteasomal subunits of the alpha and beta type. (4/580)

Clinical and laboratory manifestations of systemic sclerosis (scleroderma) in Black South Africans. (5/580)

Inosine and N1-methylinosine within a synthetic oligomer mimicking the anticodon loop of human tRNA(Ala) are major epitopes for anti-PL-12 myositis autoantibodies. (6/580)

Staging of the baboon response to group A streptococci administered intramuscularly: a descriptive study of the clinical symptoms and clinical chemical response patterns. (7/580)

Pentazocine-induced fibromyositis and contracture. (8/580)

No images available that match "myositis"

Myositis

Myositis, Inclusion Body

Polymyositis

Orbital Myositis

Dermatomyositis

Nervous System Autoimmune Disease, Experimental

Histidine-tRNA Ligase

Orbital Pseudotumor

Sarcocystis

Muscle, Skeletal

Muscle Weakness

Muscular Diseases

Autoantibodies

Thigh

The flesh-eating bacterium: what's next? (1/580)

Biodistribution, radiation dosimetry and pharmacokinetics of 111In-antimyosin in idiopathic inflammatory myopathies. (2/580)

Polymyositis with biological false-positive serological test for syphilis. A case report. (3/580)

Autoantibodies in primary Sjogren's syndrome are directed against proteasomal subunits of the alpha and beta type. (4/580)

Clinical and laboratory manifestations of systemic sclerosis (scleroderma) in Black South Africans. (5/580)

Inosine and N1-methylinosine within a synthetic oligomer mimicking the anticodon loop of human tRNA(Ala) are major epitopes for anti-PL-12 myositis autoantibodies. (6/580)

Staging of the baboon response to group A streptococci administered intramuscularly: a descriptive study of the clinical symptoms and clinical chemical response patterns. (7/580)

Pentazocine-induced fibromyositis and contracture. (8/580)

Myositis - Wikipedia

Inclusion body myositis | Bartleby

Diagnosing Myositis and Myopathy: Exam and Testing

Infectious Myositis: Background, Pathophysiology, Epidemiology

Preliminary definitions of improvement for myositis published

Myositis ossificans: Causes, risk factors, and treatment

Myositis: Symptoms, Causes, and Treatment

Myositis Causes, Symptoms, and Treatments | UPMC

History

Sporadic inclusion body myositis: new insights and potential therapy

Masticatory muscle myositis in dogs

The Myositis Association | Your Myositis Community

Anncaliia algerae Microsporidial Myositis - Volume 20, Number 2-February 2014 - Emerging Infectious Diseases journal - CDC

Masticatory Muscle Myositis - Antech Diagnostics

Myositis | Lima Memorial Health System

Statin exposure associated with idiopathic inflammatory myositis | The Hospitalist

News

May is Myositis Awareness Month | Medical Laboratory Observer

098 Developing new therapeutic strategies for inclusion body myositis | Journal of Neurology, Neurosurgery & Psychiatry

myositis-specific antibodies Archives - The Rheumatologist

Myositis Ossificans - PhysioAdvisor

Tubulinosema sp. Microsporidian Myositis in Immunosuppressed Patient

A Primer on Imaging in Myositis - The Rheumatologist

Progressive Myositis Ossificans: Report of a Case | Archives of Disease in Childhood

Frontiers | Mortality Risk Stratification Using Cluster Analysis in Patients With Myositis-Associated Interstitial Lung Disease...

Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans): Practice Essentials, Pathophysiology, Epidemiology

Information for Myositis

Myositis and its Causes - CreakyJoints

Testing treatments to improve symptoms of Myositis - Wesley Research Institute

Pneumotox » Drug » Durvalumab » X.j - Myopathy-Myositis-Polymyositis (see also under Xba)

Form of myositis6

Polymyositis8

Dermatomyositis2

Forms of myositis7

Types of myositis4

People with myositis4

Juvenile myositis16

Inclusion41

Myopathies3

Cause myositis5

Help diagnose myositis1

Myopathy5

Inflammation of the muscles4

Muscles11

Ossificans is a condition2

20221

Tests for diagnosi1

Exact cause of myositis1

Idiopathic inflammatory myositis4

20211

Type of myosi2

Masticatory muscle m8

Symptoms of myositis3

Diagnosis of myositis1

Typically2

Acute5

Severe myositis1

Clinical4