A disease characterized by bony deposits or the ossification of muscle tissue.
Inflammation of a muscle or muscle tissue.
A masticatory muscle whose action is closing the jaws; its posterior portion retracts the mandible.
Fixation and immobility of a joint.
A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms.
The development of bony substance in normally soft structures.
Progressive myopathies characterized by the presence of inclusion bodies on muscle biopsy. Sporadic and hereditary forms have been described. The sporadic form is an acquired, adult-onset inflammatory vacuolar myopathy affecting proximal and distal muscles. Familial forms usually begin in childhood and lack inflammatory changes. Both forms feature intracytoplasmic and intranuclear inclusions in muscle tissue. (Adams et al., Principles of Neurology, 6th ed, pp1409-10)
One of the two types of ACTIVIN RECEPTORS or activin receptor-like kinases (ALK'S). There are several type I activin receptors. The major active ones are ALK-2 (ActR-IA) and ALK-4 (ActR-IB).
The innermost digit of the foot in PRIMATES.

Myositis ossificans demonstrated by positive gallium-67 and technetium-99m-HMDP bone imaging but negative technetium-99m-MIBI imaging. (1/97)

Gallium-67-citrate and 99mTc-diphosphate bone imaging agents are localized in myositis ossificans, a tumor-like benign soft-tissue mass that makes it impossible to differentiate between malignant tumor and the infection/inflammatory process. We present such a myositis ossificans patient whose bone and 67Ga-citrate imagings showed increased uptake in the left thigh and two foci of the right gluteal region leading to inconclusive results. Technetium-99m-MIBI imaging showed the absence of substantial uptake in these regions. ACT scan confirmed myositis ossificans. The lack of 99mTc-MIBI uptake in myositis ossificans means that 99mTc-MIBI imaging may be useful in the differential diagnosis.  (+info)

Fibrodysplasia ossificans progressiva, a heritable disorder of severe heterotopic ossification, maps to human chromosome 4q27-31. (2/97)

Fibrodysplasia ossificans progressiva (FOP) is a severely disabling, autosomal-dominant disorder of connective tissue and is characterized by postnatal progressive heterotopic ossification of muscle, tendon, ligament, and fascia and by congenital malformation of the great toes. To identify the chromosomal location of the FOP gene, we conducted a genomewide linkage analysis, using four affected families with a total of 14 informative meioses. Male-to-male transmission of the FOP phenotype excluded X-linked inheritance. Highly polymorphic microsatellite markers covering all human autosomes were amplified by use of PCR. The FOP phenotype is linked to markers located in the 4q27-31 region (LOD score 3.10 at recombination fraction 0). Crossover events localize the putative FOP gene within a 36-cM interval bordered proximally by D4S1625 and distally by D4S2417. This interval contains at least one gene involved in the bone morphogenetic protein-signaling pathway.  (+info)

Mature bone metaplasia in abdominal wall scar. (3/97)

A 58-year-old man who had had three laparotomies for gastric surgery, developed a painful mass in the abdominal wall scar. Radiology confirmed bone formation in the scar. The bone was excised and the wound repaired. Histology confirmed metaplastic mature bone formation. This case draws the attention to the clinical condition of bone formation in midline scars. Clinically, it should be differentiated from scar recurrence following surgery for abdominal malignancy.  (+info)

Fibrodysplasia ossificans progressiva: case report. (4/97)

Fibrodysplasia ossificans progressiva is a rare genetic disease characterized by widespread soft tissue ossification and congenital stigmata of the extremities. We report on a male child followed for ten years since the age of 3 years and 9 months, when the diagnosis was made. He was born with bilateral hypoplasic hallux valgus and ventricular septal defect, corrected by trans-sternal approach when 32 months old. Restriction of neck mobility followed and foci of ectopic ossification appeared. Four crises of disease exacerbation were treated with oral prednisone and/or other antiinflammatory drugs. Sodium etidronate 5 to 10 mg/kg/day was prescribed intermittently during about six years but was discontinued due to osteopenia. The disease course has been relentless, with severe movement restriction including the chest wall. A review showed few similar case reports in the Brazilian literature. We revisit the criteria for diagnosis and the essentials of management and treatment.  (+info)

Extraskeletal osteochondroma of the buttock. (5/97)

Osteochondromas are common and typically arise from the metaphyseal ends of long bones. An osteochondral neoplasm of the soft tissue, which is a lesion of uncertain pathogenesis, is uncommon and usually arises from the synovial tissue in joints and tendon sheaths. Rarely, extraskeletal osteochondromas also arise outside of synovial compartments. Most of the reported cases were presented in the hands and feet, especially in the fingers. Here we describe a 44-yr-old female patient who presented with a pain in the left buttock. A well-defined osseous mass was detected in the buttock. It consisted of sharply demarcated, mature hyaline cartilage that was covered with a fibrous capsule, which changed gradually into cancellous bone, more pronouncedly at the center. The diagnosis of an extraskeletal osteochondroma should be considered when a discrete, ossified mass is localized in the soft tissues. A case of pathologically proven extraskeletal osteochondroma of the buttock is presented with a literature review, magnetic resonance imaging, and radiological findings.  (+info)

Fibrodysplasia ossificans progressiva (FOP). (6/97)

Fibrodysplasia ossificans progressiva (FOP) is a rare deforming disease, affecting the skeleton and is associated with progressive endochondral ossification of the striated muscles. Swelling of the soft parts is rare and can be the initial manifestation. We report three patients where initial swelling preceded the ossification.  (+info)

Histochemical and ultrastructural studies in fibrodysplasia ossificans progressiva (myositis ossificans progressiva). (7/97)

By light microscopy the subdermal nodule of a patient with fibrodysplasia ossificans progressiva (FOP) had a fibromatoid histologic appearance. The cytoplasm of the cells stained strongly for mannose-rich glycoprotein with the concanavalin A-horseradish peroxidase (con A-HRP) method. The tumors also exhibited abundant hyaluronidase-digestible mucopolysaccharide in the interstitium with various basic staining reagents. This material appeared to consist principally of hyaluronic acid or chondroitin sulfate with few or mainly masked sulfate esters. At the ultrastructural level, cells interpreted as the tumor cells in the subdermal nodule from the patient displayed extremely hyperplastic granular reticulum and well-developed Golgi elements and appeared very active in synthesis and secretion of protein. The material in the dilated cisternae of the granular reticulum stained for glycoprotein with the con-A-HRP method. Macrophages which comprised the other main cell type in the nodules commonly contacted the tumor cells and occasionally evidenced engulfment of these cells. The intercellular matrix of the nonossified subdermal nodule exhibited greatly increased mucosubstance and, by electron microscopy, showed an unusual network of dialyzed iron-reactive acid muco-substance in the interstitium.  (+info)

Chronic groin pain in an amateur soccer player. (8/97)

Chronic groin pain is common in soccer players because of the biomechanics of kicking causing recurrent stress to the abdominal muscles, groin flexors, and adductor muscles. Myositis ossificans in adductor muscles is a rare cause of chronic groin pain in soccer players. Only two cases have been reported and the iliopsoas muscle was involved in both. This case report emphasises the importance of direct radiography for diagnosis in chronic groin pain and is a reminder that the development of myositis ossificans in the adductor muscles may be a cause.  (+info)

Myositis ossificans is a medical condition characterized by the formation of bone tissue within the soft tissues, particularly in the muscles. It is also known as heterotopic ossification, which means "bone formation in an abnormal location." This condition usually occurs after trauma or injury to the muscle, such as a severe contusion (bruise) or a muscle strain or tear.

In myositis ossificans, the body's repair process goes awry, and instead of healing the muscle with normal scar tissue, bone tissue forms within the muscle. This can cause pain, stiffness, and limited mobility in the affected area. In some cases, the bone tissue may continue to grow and harden over time, leading to further complications.

Myositis ossificans is typically diagnosed through imaging tests such as X-rays, CT scans, or MRI scans, which can show the presence of bone tissue within the muscle. Treatment may include physical therapy, pain management, and in some cases, surgery to remove the excess bone tissue. Preventive measures such as early mobilization and protection of the affected area may help reduce the risk of developing myositis ossificans after an injury.

Myositis is a medical term that refers to inflammation of the muscle tissue. This condition can cause various symptoms, including muscle weakness, pain, swelling, and stiffness. There are several types of myositis, such as polymyositis, dermatomyositis, and inclusion body myositis, which have different causes and characteristics.

Polymyositis is a type of myositis that affects multiple muscle groups, particularly those close to the trunk of the body. Dermatomyositis is characterized by muscle inflammation as well as a skin rash. Inclusion body myositis is a less common form of myositis that typically affects older adults and can cause both muscle weakness and wasting.

The causes of myositis vary depending on the type, but they can include autoimmune disorders, infections, medications, and other medical conditions. Treatment for myositis may involve medication to reduce inflammation, physical therapy to maintain muscle strength and flexibility, and lifestyle changes to manage symptoms and prevent complications.

The temporalis muscle is a fan-shaped muscle located in the lateral aspect of the head, in the temporal fossa region. It belongs to the group of muscles known as muscles of mastication, responsible for chewing movements. The temporalis muscle has its origin at the temporal fossa and inserts into the coronoid process and ramus of the mandible. Its main function is to retract the mandible and assist in closing the jaw.

Ankylosis is a medical term that refers to the abnormal joining or fusion of bones, typically in a joint. This can occur as a result of various conditions such as injury, infection, or inflammatory diseases like rheumatoid arthritis. The fusion of bones can restrict movement and cause stiffness in the affected joint. In some cases, ankylosis can lead to deformity and disability if not treated promptly and effectively.

There are different types of ankylosis depending on the location and extent of bone fusion. For instance, when it affects the spine, it is called "ankylosing spondylitis," which is a chronic inflammatory disease that can cause stiffness and pain in the joints between the vertebrae.

Treatment for ankylosis depends on the underlying cause and severity of the condition. In some cases, physical therapy or surgery may be necessary to restore mobility and function to the affected joint.

Technetium Tc 99m Medronate is a radiopharmaceutical agent used in nuclear medicine for bone scintigraphy. It is a technetium-labeled bisphosphonate compound, which accumulates in areas of increased bone turnover and metabolism. This makes it useful for detecting and evaluating various bone diseases and conditions, such as fractures, tumors, infections, and arthritis.

The "Tc 99m" refers to the radioisotope technetium-99m, which has a half-life of approximately 6 hours and emits gamma rays that can be detected by a gamma camera. The medronate component is a bisphosphonate molecule that binds to hydroxyapatite crystals in bone tissue, allowing the radiolabeled compound to accumulate in areas of active bone remodeling.

Overall, Technetium Tc 99m Medronate is an important tool in nuclear medicine for diagnosing and managing various musculoskeletal disorders.

Heterotopic ossification (HO) is a medical condition where bone tissue forms outside the skeleton, in locations where it does not typically exist. This process can occur in various soft tissues, such as muscles, tendons, ligaments, or even inside joint capsules. The abnormal bone growth can lead to pain, stiffness, limited range of motion, and, in some cases, loss of function in the affected area.

There are several types of heterotopic ossification, including:

1. Myositis ossificans - This form is often associated with trauma or injury, such as muscle damage from a fracture, surgery, or direct blow. It typically affects young, active individuals and usually resolves on its own within months to a few years.
2. Neurogenic heterotopic ossification (NHO) - Also known as "traumatic heterotopic ossification," this form is often linked to spinal cord injuries, brain injuries, or central nervous system damage. NHO can cause significant impairment and may require surgical intervention in some cases.
3. Fibrodysplasia ossificans progressiva (FOP) - This rare, genetic disorder causes progressive heterotopic ossification throughout the body, starting in early childhood. The condition significantly impacts mobility and quality of life, with no known cure.

The exact mechanisms behind heterotopic ossification are not fully understood, but it is believed that a combination of factors, including inflammation, tissue injury, and genetic predisposition, contribute to its development. Treatment options may include nonsteroidal anti-inflammatory drugs (NSAIDs), radiation therapy, physical therapy, or surgical removal of the abnormal bone growth, depending on the severity and location of the HO.

Inclusion body myositis (IBM) is a rare inflammatory muscle disease characterized by progressive weakness and wasting (atrophy) of skeletal muscles. The term "inclusion body" refers to the presence of abnormal protein accumulations within muscle fibers, which are observed under a microscope during muscle biopsy. These inclusions are primarily composed of aggregated forms of amyloid-β and tau proteins, similar to those found in neurodegenerative disorders like Alzheimer's disease.

IBM typically affects individuals over 50 years old, and it is more common in men than women. The disease usually starts with weakness in the wrist and finger flexors, making it difficult to perform tasks such as gripping, buttoning shirts, or lifting objects. Over time, the weakness spreads to other muscle groups, including the thigh muscles (quadriceps), resulting in difficulty climbing stairs or rising from a seated position.

The exact cause of inclusion body myositis remains unclear; however, both immune-mediated and degenerative mechanisms are believed to contribute to its pathogenesis. Currently, there is no cure for IBM, and treatment options are primarily aimed at managing symptoms and improving quality of life. Immunosuppressive medications may be used to target the inflammatory component of the disease; however, their efficacy varies among patients. Physical therapy and exercise programs can help maintain muscle strength and function as much as possible.

Activin receptors, type I are serine/threonine kinase receptors that play a crucial role in the activin signaling pathway. There are two types of activin receptors, Type I (ALK2, ALK4, and ALK7) and Type II (ActRII and ActRIIB). Activin receptors, type I are transmembrane proteins that bind to activins, which are cytokines belonging to the TGF-β superfamily.

Once activated by binding to activins, activin receptors, type I recruit and phosphorylate type II receptors, leading to the activation of downstream signaling pathways, including SMAD proteins. Activated SMAD proteins then translocate to the nucleus and regulate gene expression, thereby mediating various cellular responses such as proliferation, differentiation, apoptosis, and migration.

Mutations in activin receptors, type I have been implicated in several human diseases, including cancer, fibrosis, and developmental disorders. Therefore, understanding the structure and function of activin receptors, type I is essential for developing novel therapeutic strategies to treat these diseases.

"Hallux" is a medical term that refers to the big toe or great toe, which is the first digit of the human foot. It is derived from Latin, where "hallus" means "big toe." In some contexts, specific pathologies or conditions related to the big toe may also be referred to as hallux issues, such as hallux valgus (a common foot deformity where the big toe drifts toward the second toe) or hallux rigidus (a form of degenerative arthritis that affects the big toe joint).

The term myositis ossificans traumatica is sometimes used when the condition is due to trauma. Also myositis ossificans ... nonhereditary myositis ossificans (commonly referred to simply as "myositis ossificans", as in the remainder of this article), ... Myositis Ossificans". Ultrasound of the Shoulder. Master Medical Books. Lacout, Alexis (Jan-Mar 2012). "Myositis ossificans ... "Myositis ossificans". Walczak, Brian E; Johnson, Christopher N; Howe, B, Matthew (October 2015). "Myositis Ossificans". Journal ...
Myositis ossificans. Surg Gynec Obstet 1924, 39, 795-802. Pseudocoxalgia. J Bone Jt Surg 1925, 7, 70-84. Klippel-Feils syndrome ...
Myositis ossificans traumatica (circumscripta) - Possible, but unlikely source. Avulsion injury - McWhinney and the other ...
Dorpat, 1883 Zur Casuistik der Myositis ossificans multiplex (progressiva). Berliner klinische Wochenschrift 29, ss. 1163-1165 ...
The quadriceps femoris muscle is the most common site of myositis ossificans. In strength training, the quadriceps are trained ...
Calcification of muscle can occur after traumatic injury and is known as myositis ossificans. It can be recognized by muscle ...
Compounding the situation was the fact that Neely developed myositis ossificans in the injured area. The injury kept Neely out ...
She studied muscles extensively, in their pathology and nervous connections, as well as the disease myositis ossificans. Other ...
Deller A, Heuer B, Wiedeck H (December 1998). "Is myositis ossificans following ARDS a complication of prone-dependency or is ...
Myositis ossificans and fibro-osseous pseudotumor of digits: The World Health Organization, 2021, classified these two tumors ... "Myositis ossificans - Another condition with USP6 rearrangement, providing evidence of a relationship with nodular fasciitis ...
Intramembranous ossification Myositis ossificans Fibrodysplasia ossificans progressiva Progressive osseous heteroplasia Brance ... In traumatic heterotopic ossification (traumatic myositis ossificans), the patient may complain of a warm, tender, firm ... There are also rare genetic disorders causing heterotopic ossification such as fibrodysplasia ossificans progressiva (FOP), a ...
FOP was originally called myositis ossificans progressiva and was thought to be caused by muscular inflammation (myositis) that ... FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue ... While Fibrodysplasia Ossificans Progressiva (FOP) remains without a cure, a promising breakthrough lies in the approved ... "Fibrodysplasia ossificans progressiva", Genetics Home Reference, U.S. National Library of Medicine, August 2007. Accessed ...
Myositis ossificans and fibro-osseous pseudotumor of digits, previously considered separate but similar tumors, are ... Benign FMTs Nodular fasciitis Proliferative fasciitis and proliferative myositis, originally considered separate entities, are ... "Recurrent FOS rearrangement in proliferative fasciitis/proliferative myositis". Modern Pathology. 34 (5): 942-950. doi:10.1038/ ...
... when he was finally diagnosed with Myositis ossificans progressiva, which is now known as Fibrodysplasia Ossificans Progressiva ... "Fibrodysplasia ossificans progressiva (FOP) - Teaching Learners with Special Needs - MSSE.704.01 - (2135) - RIT Wiki". wiki.rit ... "Fibrodysplasia Ossificans Progressiva (FOP)". The College of Physicians of Philadelphia Digital Library. Digitized by the ... "Fibrodysplasia Ossificans Progressiva - NORD (National Organization for Rare Disorders)". NORD (National Organization for Rare ...
The accident resulted in a haematoma in her left thigh, causing - in an example of myositis ossificans - a 5 cm spur of bone to ...
... severe Myorhythmia Myositis ossificans post-traumatic Myositis ossificans progressiva Myositis ossificans Myositis, inclusion ... body Myositis Myotonia atrophica Myotonia mental retardation skeletal anomalies Myotubular myopathy Myxedema Myxoid liposarcoma ...
... myositis, inclusion body MeSH C05.651.594.638 - myositis ossificans MeSH C05.651.594.819 - polymyositis MeSH C05.651.594.819. ...
... forward Cam Neely with a knee-on-knee check that injured Neely and caused him to develop a condition called myositis ossificans ...
... parasitic myositis, osteomyelitis, calcific myonecrosis, myositis ossificans, diabetic myotrophy, muscle strain or rupture, ...
... acquired Progressive multifocal leukoencephalopathy Progressive myositis ossificans Progressive osseous heteroplasia ...
M60.9) Benign acute childhood myositis (M61) Myositis ossificans (M62.89) Rhabdomyolysis and (R82.1) myoglobinurias The Food ... Inclusion body myositis is a slowly progressive disease that produces weakness of hand grip and straightening of the knees. No ... Some conditions, such as myositis, can be considered both neuromuscular and musculoskeletal. Common symptoms include muscle ... inclusion body myositis, viral (HIV) Infectious myopathies Endocrine myopathies - thyroid, parathyroid, adrenal, pituitary ...
Myositis ossificans High-arched foot Genu valgus Congenital heart defect These are the syndromes associated with this ...
... a condition known as myositis ossificans. Despite the injury and extended time out of action, Brickley was allowed to briefly ...
The term myositis ossificans traumatica is sometimes used when the condition is due to trauma. Also myositis ossificans ... nonhereditary myositis ossificans (commonly referred to simply as "myositis ossificans", as in the remainder of this article), ... Myositis Ossificans". Ultrasound of the Shoulder. Master Medical Books. Lacout, Alexis (Jan-Mar 2012). "Myositis ossificans ... "Myositis ossificans". Walczak, Brian E; Johnson, Christopher N; Howe, B, Matthew (October 2015). "Myositis Ossificans". Journal ...
Myositis ossificans is a condition where bone tissue forms inside muscle or other soft tissue after an injury. Learn about the ... Myositis ossificans is often caused by a single traumatic injury.. Myositis ossificans usually occurs where a person has ... Very rarely, myositis ossificans can occur after a severe muscle strain.. Regardless of the cause, myositis ossificans happens ... An MRI may help diagnose myositis ossificans.. Before diagnosing myositis ossificans, a doctor will ask about what happened, ...
Fibrodysplasia ossificans progressiva (FOP) is a rare and disabling genetic condition characterized by congenital malformations ... Myositis Ossificans)) and Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) What to Read Next on Medscape ... Myositis ossificans is a misnomer, although the term myositis ossificans circumscripta continues to be used to describe ... Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) * Sections Pediatric Fibrodysplasia Ossificans ...
PhysioAdvisor offers detailed physiotherapy information on myositis ossificans including: causes, symptoms, diagnosis, ... This condition is known as myositis ossificans.. Causes of myositis ossificans. Myositis ossificans is a rare condition that ... What is myositis ossificans?. Myositis ossificans is an uncommon condition that may occur following a thigh contusion (bruised ... Exercises for myositis ossificans. The following exercises are commonly prescribed to patients with myositis ossificans. You ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Fibrodysplasia ossificans progressiva (FOP) is a rare and disabling genetic condition characterized by congenital malformations ... Myositis Ossificans)) and Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) What to Read Next on Medscape ... Myositis ossificans is a misnomer, although the term myositis ossificans circumscripta continues to be used to describe ... Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) * Sections Pediatric Fibrodysplasia Ossificans ...
Myositis Ossificans is a reactive soft tissue bone-forming process that commonly occurs following a traumatic event to soft ... Fibrodysplasia ossificans progressiva (FOP) is a rare subtype of heterotopic ossification * involves mutation of the ACVR1 gene ...
Myositis ossificans is a condition characterized by ossification within a muscle. It is a rare and unusual pathologic entity ... Myositis ossificans of the temporalis muscle is a very rare case. Satisfactory outcome was obtained by combining surgical ...
Fibrodysplasia ossificans progressiva (FOP) is a rare and disabling genetic condition characterized by congenital malformations ... Myositis Ossificans)) and Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) What to Read Next on Medscape ... Myositis ossificans is a misnomer, although the term myositis ossificans circumscripta continues to be used to describe ... Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) * Sections Pediatric Fibrodysplasia Ossificans ...
We present a case of pseudomalignant myositis ossificans involving medial pterygoid, lateral pterygoid, and temporalis mus ... Myositis ossificans is a rare cause of trismus. ... Myositis ossificans is a rare cause of trismus. We present a ... Keywords: Pseudomalignant myositis ossificans; pterygoid muscles; temporal muscle. References *Am J Sports Med. 1987 Mar-Apr;15 ... Pseudomalignant myositis ossificans involving multiple masticatory muscles: Imaging evaluation. Indian J Radiol Imaging. 2014; ...
Fibrodysplasia ossificans progressiva (FOP) is a rare and disabling genetic condition characterized by congenital malformations ... Myositis Ossificans)) and Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) What to Read Next on Medscape ... Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) * Sections Pediatric Fibrodysplasia Ossificans ... Pediatric Fibrodysplasia Ossificans Progressiva (Myositis Ossificans) Medication. Updated: Sep 19, 2013 * Author: Robert J ...
... and effective management strategies for Myositis Ossificans triggered by direct trauma or repetitive strain. Essential reading ... Delve into the complex relationship between trauma and Myositis Ossificans through our comprehensive article. Packed with real- ... What is Myositis Ossificans?. Myositis ossificans (MO) is characterized by the abnormal growth of bone tissue in places where ... The Connection Between Trauma and Myositis Ossificans. *Direct Trauma: The most common cause of Myositis ossificans is direct ...
Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) - Clinic … Market Research HUBs latest Pharmaceutical ... Myositis Ossificans Progressiva) - Pipeline Review, H1 2017, provides an overview of the Fibrodysplasia Ossificans Progressiva ... Myositis Ossificans Progressiva) (Musculoskeletal Disorders) pipeline landscape. Request Free Sample Report: http://www. ... marketresearchhub.com/enquiry.php?type=enquiry&repid=1196670 Fibrodysplasia Ossificans Progressiva (FOP) is a disorder in which ...
Myositis Ossificans. Posted on August 11, 2011. by Allison Bond A muscle contusion, when the skin and underlying tissue become ... Posted in Other Sports Injuries , Tagged Allison Bond, injury, Myositis Ossificans, sports injury Snapping Hip Syndrome. Posted ... Myositis ossificans is not detectable immediately; initially, symptoms are those of a contusion, such as pain, tenderness and ... If you suspect you have developed myositis ossificans, consult a sports medicine specialist. He or she will examine the area, ...
Myositis Ossificans. High Quality Pathology Images of Soft Tissue, Misc. Soft Tissue Lesions, Heterotopic Ossification. ... Myositis Ossificans. Home "> Soft Tissue "> Misc. Soft Tissue Lesions "> Heterotopic Ossification "> Myositis Ossificans ...
Ankylosing neurogenic myositis ossificans of the hip: AN ENHANCED VOLUMETRIC CT STUDY. Health and Medicine Reference Covering ... Myositis. Myositis ossificans. Myxedema. Myxozoa. N. O. P. Q. R. S. T. U. V. W. X. Y. Z. Medicines. Read more at Wikipedia.org ... Neurogenic myositis ossificans occurs most often in immobile patients with head or spinal-cord injury. It may also be seen as a ... Ankylosing neurogenic myositis ossificans of the hip: AN ENHANCED VOLUMETRIC CT STUDY. From Journal of Bone and Joint Surgery, ...
Myositis ossificans is a potentially disabling complication from quadriceps contusions and risk factors, prevention, and ...
Myositis ossificans, see Fibrodysplasia ossificans progressiva. *Myositis ossificans progressiva, see Progressive osseous ...
Soft Tissue Evaluation and Myositis Ossificans. by Douglas Gregerson, DC, DACBR , Jul 13, 2022 , Clinical, Radiology, zall , 0 ...
Myositis ossificans. *Osteoarthritis. Pathophysiology Edit Main article: Bone healing. Stages in Fracture Repair: The healing ...
The myositis ossificans caused the injured muscle to turn to bone; as a result, Neely now carries around a brick-sized chunk of ... and Samuelssons knee drove into Neelys thigh with such force that it caused a rare condition called myositis ossificans. ...
Myositis ossificans of the longus coli muscle following cervical spine fracture-dislocation.﻽. Raudenbush BL, McCalla D, Mesfin ... Arachnoiditis ossificans after revision adolescent idiopathic scoliosis surgery: a 22-year follow-up and review.﻽. Bakhsh WR, ...
Myositis Ossificans of the temporalis muscle: case report and review of the literature. J Oral Maxillofac Surg. 2013;71:1893-8. ... Post-infectious myositis ossificans in medial, lateral pterygoid muscles: a case report and review of the literature. Oncol ... Aoki T, Naito H, Ota Y, Shiiki K. Myositis Ossificans traumatina of the masticatory muscles: review of the literature and ... Fité-Trepat L, Martos-Fernández M, Alberola-Ferranti M, Romanini-Montecino C, Saez-Barba M, Bescós-Atín C. Myositis ossificans ...
Myositis Ossificans Mario Ciocca. Arthritides Adam Carlson. Infections (Septic Joint, Septic Arthritis, ...
After healing, ultrasound can depict some complications such as a cystic lesion or myositis ossificans. Muscle atrophy, ... or myositis ossificans. When dealing with fresh traumatic muscle lesions, the main goal of ultrasound is to assess the presence ...
myositis ossificans. myositis ossificans, disorder of unknown cause in which connective tissue and muscle are replaced by bone ... myositis. myositis, inflammation, and frequently infection, of muscle tissue; it may be caused by any of a number of bacteria ...
Myositis Ossificans in Doberman Pinschers * For More Information * Polymyositis in Dogs * For More Information ...
Injuries due to needle use: Drug abusers elbow (myositis ossificans) is caused by repeated, inept needle punctures. The muscle ...
  • The term myositis ossificans traumatica is sometimes used when the condition is due to trauma. (wikipedia.org)
  • Also myositis ossificans circumscripta is another synonym of myositis ossificans traumatica refers to the new extraosseous bone that appears after trauma. (wikipedia.org)
  • Myositis Ossificans Traumatica in the Temporalis Muscle. (e-acfs.org)
  • The second condition, myositis ossificans progressiva (also referred to as fibrodysplasia ossificans progressiva) is an inherited affliction, autosomal dominant pattern, in which the ossification can occur without injury, and typically grows in a predictable pattern. (wikipedia.org)
  • Extensive heterotopic ossification on the back of a patient with fibrodysplasia ossificans progressiva. (medscape.com)
  • Fibrodysplasia ossificans progressiva is the most catastrophic disorder of heterotopic ossification in humans. (medscape.com)
  • Progressive postnatal heterotopic ossification in fibrodysplasia ossificans progressiva usually appears within the first decade of life as spontaneous or injury-induced exacerbations. (medscape.com)
  • Mounting evidence from all levels of investigation suggests involvement of the inflammatory component of the immune system in fibrodysplasia ossificans progressiva. (medscape.com)
  • The presence of macrophages, lymphocytes and mast cells in early fibrodysplasia ossificans progressiva lesions, macrophage and lymphocyte-associated death of skeletal muscle, flare-ups following viral infections, the intermittent timing of flare-ups, and the beneficial response of early flare-ups to corticosteroids support involvement of the innate immune system in the pathogenesis of fibrodysplasia ossificans progressiva lesions. (medscape.com)
  • The genetic cause of fibrodysplasia ossificans progressiva was identified as a recurrent missense mutation in the GS activation domain of activin receptor Ia/activinlike kinase 2 ( ACVR1/ALK2 ), a bone morphogenetic protein (BMP) type I receptor, in all individuals with classic fibrodysplasia ossificans progressiva. (medscape.com)
  • [ 4 , 5 ] Recently, additional mutations have been identified in the GS-domain and kinase domain of ACVR1 in individuals with atypical forms of fibrodysplasia ossificans progressiva. (medscape.com)
  • Fibrodysplasia ossificans progressiva is rare with a worldwide prevalence of approximately 1 case in 2 million individuals. (medscape.com)
  • As heterotopic bone accumulates in fibrodysplasia ossificans progressiva, range of motion is progressively lost, leading to near complete immobility. (medscape.com)
  • Patients with fibrodysplasia ossificans progressiva develop thoracic insufficiency syndrome (TIS) that can lead to life-threatening complications. (medscape.com)
  • Pneumonia and right-sided heart failure are the major life-threatening hazards that result from TIS in patients with fibrodysplasia ossificans progressiva. (medscape.com)
  • Current challenges and opportunities in the care of patients with fibrodysplasia ossificans progressiva (FOP): an international, multi-stakeholder perspective. (medscape.com)
  • The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. (medscape.com)
  • Fibrodysplasia ossificans progressiva: clinical and genetic aspects. (medscape.com)
  • A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. (medscape.com)
  • Fibrodysplasia ossificans progressiva (FOP) is a rare and disabling genetic condition characterized by congenital malformations of the great toes and progressive heterotopic ossification (HO) in specific anatomic patterns. (medscape.com)
  • Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1. (medscape.com)
  • Age- and joint-specific risk of initial heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. (medscape.com)
  • Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome: clues from the BMP signaling pathway. (medscape.com)
  • Proximal tibial osteochondromas in patients with fibrodysplasia ossificans progressiva. (medscape.com)
  • Iatrogenic harm caused by diagnostic errors in fibrodysplasia ossificans progressiva. (medscape.com)
  • Radiographic and scintigraphic features of modeling and remodeling in the heterotopic skeleton of patients who have fibrodysplasia ossificans progressiva. (medscape.com)
  • Early diagnosis of fibrodysplasia ossificans progressiva. (medscape.com)
  • Tumorlike swellings on the back representing early fibrodysplasia ossificans progressiva (FOP) flare-ups. (medscape.com)
  • Severe limb swelling seen with an fibrodysplasia ossificans progressiva (FOP) flare-up. (medscape.com)
  • Myositis ossificans is a misnomer, although the term myositis ossificans circumscripta continues to be used to describe nonhereditary forms of heterotopic ossification. (medscape.com)
  • However, it is not 100 percent reliable, and if a doctor suspects that someone has myositis ossificans, they may carry out additional testing to make the diagnosis. (medicalnewstoday.com)
  • Radiological diagnosis was pseudomalignant myositis ossificans. (uiindex.org)
  • The availability, low cost, and ease of examination makes ultrasound superior to MRI for follow-up of lesions and searching for healing problems such as as fibrosis, cystic haematomas, or myositis ossificans. (nih.gov)
  • In the first, and by far most common type, nonhereditary myositis ossificans (commonly referred to simply as "myositis ossificans", as in the remainder of this article), calcifications occur at the site of injured muscle, most commonly in the arms or in the quadriceps of the thighs. (wikipedia.org)
  • Myositis ossificans is a rare condition that may develop following a quadriceps contusion. (physioadvisor.com.au)
  • Diligently following the R.I.C.E. Regime in the initial phase of injury (first 72 hours) will greatly reduce the likelihood of a quadriceps contusion developing into myositis ossificans. (physioadvisor.com.au)
  • Myositis ossificans is a potentially disabling complication from quadriceps contusions and risk factors, prevention, and treatment are reviewed. (nih.gov)
  • Pseudomalignant myositis ossificans involving multiple masticatory muscles: Imaging evaluation. (uiindex.org)
  • Kamalapur MG, Patil PB, Joshi S, Shastri D. Pseudomalignant myositis ossificans involving multiple masticatory muscles: Imaging evaluation. (uiindex.org)
  • Aoki T, Naito H, Ota Y, Shiiki K. Myositis Ossificans traumatina of the masticatory muscles: review of the literature and report of a case. (springer.com)
  • A muscle strain or muscle contusion (bruise) can sometimes result in an unfortunate complication called myositis ossificans (MO). (moreaupt.com)
  • A case of myositis ossificans as a complication of tetanus treated by surgical excision. (actaorthopaedica.be)
  • myositis ossificans, disorder of unknown cause in which connective tissue and muscle are replaced by bone. (britannica.com)
  • In the late stage, termed mature, myositis ossificans is depicted as an elongated calcific deposit that is aligned with the long-axis of the muscle, exhibits acoustic shadowing, and has no soft tissue mass associated. (wikipedia.org)
  • A main concern is to differentiate early myositis ossificans from malignant soft-tissue tumors, and the latter is suggested by a fast-growing process. (wikipedia.org)
  • Since myositis ossificians is more common in those with bleeding disorders, the formation of bone in soft tissue is thought to be associated with haematoma formation. (wikipedia.org)
  • Myositis ossificans is a condition where bone tissue forms inside muscle or other soft tissue after an injury. (medicalnewstoday.com)
  • Sometimes, early diagnostic testing can confuse myositis ossificans with certain types of soft tissue cancers . (medicalnewstoday.com)
  • Myositis Ossificans is a reactive soft tissue bone-forming process that commonly occurs following a traumatic event to soft tissues. (orthobullets.com)
  • Heterotopic ossification may occur for no known reason as in myositis ossificans progressiva or may follow a wide variety of surgical, occupational, and sports trauma (e.g., hip arthroplasty, spinal cord injury, head injury, burns, and severe thigh bruises). (nih.gov)
  • We present a case of pseudomalignant myositis ossificans involving medial pterygoid, lateral pterygoid, and temporalis muscles. (uiindex.org)
  • Pseudomalignant myositis ossificans of the wrist causing compression of the ulnar nerve and artery. (actaorthopaedica.be)
  • If pain relievers, physical therapy, and other home care measures are not effective in treating myositis ossificans, surgical removal of the growth may be needed. (medicalnewstoday.com)
  • The World Health Organization, 2020, has grouped myositis ossificans together with fibro-osseous pseudotumor of digits as a single specific entity in the category of fibroblastic and myofibroblastic tumors. (wikipedia.org)
  • These imaging tests are vital in distinguishing Myositis ossificans from other conditions like bone tumors. (epainassist.com)
  • Myositis ossificans is an uncommon condition that may occur following a thigh contusion (bruised thigh) and is characterized by bone formation (calcification) in the muscle belly at the site of the bruise. (physioadvisor.com.au)
  • At histology, detection of the typical zonal phenomenon is diagnostic of myositis ossificans, though microscopic findings may be misleading during the early stage. (wikipedia.org)
  • Enhanced volumetric CT is an excellent method for the pre-operative assessment of neurogenic myositis ossificans and correlates well with the operative findings. (the-medical-dictionary.com)
  • Neurogenic myositis ossificans is the formation of heterotopic bone in the periarticular soft tissues of patients who have sustained a severe injury to the brain or spinal cord. (the-medical-dictionary.com)
  • After healing, ultrasound can depict some complications such as a cystic lesion or myositis ossificans. (nih.gov)
  • Myositis ossificans of the temporalis muscle is a very rare case. (e-acfs.org)
  • Myositis ossificans usually occurs where a person has experienced a single traumatic injury, such as sustaining a hit while playing football or soccer that causes a deep muscle bruise. (medicalnewstoday.com)
  • Also, people who are paralyzed from the waist down are more likely to develop myositis ossificans, even if they do not have a specific injury. (medicalnewstoday.com)
  • Before diagnosing myositis ossificans, a doctor will ask about what happened, how long ago it happened, the symptoms, and what steps a person has taken to manage the pain or injury. (medicalnewstoday.com)
  • Within a few weeks following injury, further symptoms may then start to develop which suggest the presence of myositis ossificans. (physioadvisor.com.au)
  • We established that early surgery, within 24 months of injury, was neither complicated by peri-operative fracture nor by the early recurrence of neurogenic myositis ossificans. (the-medical-dictionary.com)
  • Most of the time, myositis ossificans occurs in the large muscles of the arms or the legs. (medicalnewstoday.com)
  • Myositis ossificans, a condition where bone tissue forms in muscles or other soft tissues, is often linked to trauma. (epainassist.com)
  • Myositis ossificans (MO) is characterized by the abnormal growth of bone tissue in places where bone typically doesn't form, like muscles or soft tissues. (epainassist.com)
  • The most common cause of Myositis ossificans is direct trauma to muscles, often seen in athletes, accident victims, or those with physically demanding jobs. (epainassist.com)
  • Imaging studies showed heterotopic ossification within the muscles of his forearm, consistent with Myositis ossificans. (epainassist.com)
  • It can be hard to predict who will get myositis ossificans, but the condition is more prevalent in active young adults and athletes. (medicalnewstoday.com)
  • Myositis ossificans occurs in people who participate in sport at all levels, from those who are playing just for fun through to highly competitive or professional athletes. (medicalnewstoday.com)
  • They are one early diagnostic test that can be used to look for the changes associated with myositis ossificans. (medicalnewstoday.com)
  • Neurogenic myositis ossificans is a disabling condition affecting the large joints of patients with severe post-traumatic impairment of the central nervous system. (the-medical-dictionary.com)
  • Myositis ossificans comprises two syndromes characterized by heterotopic ossification (calcification) of muscle. (wikipedia.org)
  • Unlike other typical muscle strains or injuries, people with myositis ossificans may notice that their pain worsens with time instead of getting better. (medicalnewstoday.com)
  • Repetitive minor injuries or strains can also lead to Myositis ossificans. (epainassist.com)
  • Postoperative complications included deep (2 patients) and superficial (2 patients) infections, malunion in two patients, arthrofibrosis in three patients, and myositis ossificans in one patient. (aott.org.tr)
  • The process of myositis ossificans can be divided into three stages: early, intermediate, and mature. (wikipedia.org)
  • It can be difficult to diagnose myositis ossificans in the early stages with just an X-ray. (medicalnewstoday.com)
  • This condition is known as myositis ossificans. (physioadvisor.com.au)
  • Myositis ossificans is a condition characterized by ossification within a muscle. (e-acfs.org)
  • Neely collided with Pittsburgh Penguins player Ulf Samuelsson, and Samuelsson's knee drove into Neely's thigh with such force that it caused a rare condition called myositis ossificans. (encyclopedia.com)
  • Imaging studies revealed Myositis ossificans within the hematoma. (epainassist.com)
  • This article explores the relationship between trauma and myositis ossificans, backed by insights and illustrative case studies. (epainassist.com)
  • A case study of a high-school football player who developed Myositis ossificans in his thigh after a direct hit during a game. (epainassist.com)
  • We undertook pre-operative volumetric CT assessment of 45 ankylosed hips with neurogenic myositis ossificans which required surgery. (the-medical-dictionary.com)
  • Surgery for neurogenic myositis ossificans was performed by the same orthopaedic surgeon (PD) at a mean of 44.5 months (7 to 185) after the initial trauma. (the-medical-dictionary.com)
  • A thorough subjective and objective examination from a physiotherapist can usually predict the likelihood of the presence of myositis ossificans. (physioadvisor.com.au)
  • Timely and effective treatment of initial traumas is key to preventing Myositis ossificans development. (epainassist.com)
  • While not a direct cause, genetic predisposition may play a role in an individual's susceptibility to Myositis ossificans. (epainassist.com)
  • Some individuals may have genetic variants that increase their risk of developing Myositis ossificans following trauma. (epainassist.com)
  • Although neurogenic myositis ossificans may develop in any joint, it usually involves the large joints, often the hips and, less commonly, the knees, elbows and shoulders. (the-medical-dictionary.com)
  • The exact reason as to why some of these contusions then go on to develop into myositis ossificans is not exactly known. (physioadvisor.com.au)
  • The formation of a hematoma , or a collection of blood within the muscle, following trauma is often associated with Myositis ossificans. (epainassist.com)