A condition characterized by a dry, waxy type of swelling (EDEMA) with abnormal deposits of MUCOPOLYSACCHARIDES in the SKIN and other tissues. It is caused by a deficiency of THYROID HORMONES. The skin becomes puffy around the eyes and on the cheeks. The face is dull and expressionless with thickened nose and lips.
A nonspecific term used to denote any cutaneous lesion or group of lesions, or eruptions of any type on the leg. (From Stedman, 25th ed)
A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA.
Lower than normal body temperature, especially in warm-blooded animals.
A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

Regulation of thyrotropin receptor protein expression in insect cells. (1/96)

Expression of large quantities of conformationally intact thyrotropin receptor (TSHR) is essential to understand the structure-function relationship of the receptor. We expressed three different constructs of full-length human TSHR in insect cells: (a) a TSHR cDNA lacking signal sequence (TSHR-ns), (b) a TSHR cDNA containing human TSHR signal sequence (TSHR-hs) and (c) a TSHR cDNA with baculovirus envelope protein encoded signal sequence gp-67 (TSHR-gp). No unique protein band, corresponding to any of these recombinant proteins, was visible upon Coomassie Blue staining after SDS-PAGE. However, Western blot using TSHR specific monoclonal antibody showed unique bands around 80, 100 and 100 kDa in TSHR-ns, TSHR-hs and TSHR-gp virus infected insect cells respectively. All three full-length TSHR proteins could neutralize the TSH binding inhibitory immunoglobulin (TBII) activity from sera of experimental animals. However, only glycosylated proteins (TSHR-hs and TSHR-gp) neutralized the TBII activity of sera from autoimmune thyroid patients, confirming the importance of glycosylation for patient autoantibody reactivity. Expression levels of full-length TSHR proteins were much lower than the levels of similarly produced corresponding ectodomains of TSHR proteins. Southern blot and Northern blot analyses showed that DNA and RNA levels in full-length TSHR virus infected insect cells were comparable to the levels found in cells infected with viruses encoding only the ectodomain of TSHR. These data suggest that full-length TSHR expression is very low and is regulated at the translational level.  (+info)

Aorto-coronary dissection during angioplasty in a patient with myxedema. (2/96)

A 67-year-old man with overt hypothyroidism and medically controlled hypertension was admitted for coronary angiography because of exertional angina. His triiodothyronine (T3) and thyroxine (T4) levels had been low for 4 years. Although signs and symptoms of hypothyroidism were apparent, his hypercholesterolemia was mild. Coronary angiography revealed an eccentric stenosis in the distal portion of the right coronary artery and it was decided to perform angioplasty because his angina had continued in spite of medication. The dissection appeared at the lesion site after the first nominal inflation, and a subsequent image disclosed a spiral dissection from the dilated site to the aortic sinus and peripheral coronary artery. Although emergency stenting could not prevent the extension near the origin of the brachiocephalic artery, the false lumen thrombosed and then diminished with conservative therapy. Aorto-coronary dissection is potentially life-threatening and has been recently reported as a complication during cardiac catheterization procedures. Chronic hypothyroid insufficiency may be one of the risk factors for this complication.  (+info)

Myxedema coma: diagnosis and treatment. (3/96)

Myxedema coma, the extreme manifestation of hypothyroidism, is an uncommon but potentially lethal condition. Patients with hypothyroidism may exhibit a number of physiologic alterations to compensate for the lack of thyroid hormone. If these homeostatic mechanisms are overwhelmed by factors such as infection, the patient may decompensate into myxedema coma. Patients with hypothyroidism typically have a history of fatigue, weight gain, constipation and cold intolerance. Physicians should include hypothyroidism in the differential diagnosis of every patient with hyponatremia. Patients with suspected myxedema coma should be admitted to an intensive care unit for vigorous pulmonary and cardiovascular support. Most authorities recommend treatment with intravenous levothyroxine (T4) as opposed to intravenous liothyronine (T3). Hydrocortisone should be administered until coexisting adrenal insufficiency is ruled out. Family physicians are in an important position to prevent myxedema coma by maintaining a high level of suspicion for hypothyroidism.  (+info)

Thyroxine treatment induces upregulation of renin-angiotensin-aldosterone system due to decreasing effective plasma volume in patients with primary myxoedema. (4/96)

BACKGROUND: In experimental animals and humans, hypothyroidism is associated with fluid retention and generalized oedema, increased antidiuretic hormone (ADH), decreased atrial natriuretic hormone (ANH), and decreased renin-angiotensin-aldosterone system (RAAS), which subsequently can be corrected by thyroid hormone replacement. The purpose of this study was to determine the effect of thyroxine therapy on RAAS and neurohormones affecting water and electrolyte metabolism and the reason for these changes in patients with primary myxoedema. METHODS: We measured changes in the plasma renin activity (PRA), serum aldosterone (Aldo), ADH, ANH levels, serum and 24 h urinary electrolytes and osmolalities, and cardiac function in 22 female patients with primary myxoedema before and after correction of hypothyroidism. We also evaluated age-, sex-, and BMI-matched 15 healthy control subjects (Cont). RESULTS: It took an average of 4.3 months (range, 3-9 months) to normalize thyroid function. The mean reductions of body weight and estimated plasma volume were 1.8+/-1.0 kg (P=0.002) and 8.5% (P<0.001), respectively. In addition, serum Na+ and osmolality and the haematocrit were significantly elevated after correction of hypothyroidism (P<0.01 and P<0.001, respectively). Increased F(E)Na and C(OSM) (P<0.05) levels in patients with hypothyroidism (Ho) compared with those in Cont did not change after thyroxine therapy (Eu). However, C(H(2)O), U(E)K, F(E)K, and TTKG levels as well as creatinine clearance (Ccr) were markedly increased in Eu compared with Ho and Cont (P<0.01, respectively). Increased plasma ADH concentration and decreased plasma ANH concentration were normalized compared to Cont after thyroxine therapy (P<0.001 and P<0.01, respectively). Low PRA and serum Aldo concentration in Ho were significantly increased in Eu (P<0.001 and P<0.01, respectively). In addition, increased left ventricular mass index and decreased cardiac output in Ho were normalized compared to Cont after thyroxine therapy (P<0.01, respectively) CONCLUSIONS: These findings suggest that the exaggerated upregulation of RAAS after correction of hypothyroidism in patients with primary myxoedema is associated with an increase in Ccr and a decrease in plasma volume resulting from water diuresis, natriuresis, osmotic diuresis and inappropriate changes in plasma ADH and ANH levels. The improved renal function coincided with an amelioration of cardiac function. These changes seem to be an adaptive response for preventing excessive plasma volume and weight loss after thyroxine therapy.  (+info)

Exophthalmus-myxoedema circumscriptum praetibiale-osteoarthropathia hypertrophicans (E.M.O.) syndrome in Graves' disease: a review of eight cases reported in Japan. (5/96)

Case 1 showed recurrence of hyperthyroidism accompanied by pretibial myxedema and digital clubbing 14 years after thyroidectomy for Graves' disease. Case 2 had had pretibial myxedema for the past 20 years and myxedema tuberosum at the right shoulder for the past 10 years, and on admission showed exophthalmos and digital clubbing with thyroid gland demonstrating histological picture of chronic thyroiditis. This case was in slight hypothyroidism and serum LATS was highly positive. Eight cases of E.M.O. syndrome have so far been reported in Japan, including our own. Six cases of these were males. Two cases did not show any sign of hyperthyroidism throughout their entire courses, including our Case 2 described here. Three cases had never received treatment for Graves' disease prior to the occurrence of this syndrome. The serum LATS was positive in all 5 cases thus far reported.  (+info)

Evidence for thyrotropin receptor immunoreactivity in pretibial connective tissue from patients with thyroid-associated dermopathy. (6/96)

Pretibial myxedema (PTM), mainly characterized by the accumulation of glycosaminoglycans in the dermis and subcutaneous tissue, is an extrathyroidal manifestation of autoimmune Graves' disease (GD), almost always associated with Graves' ophthalmopathy (GO). The thyrotropin receptor (TSH-R) has been proposed as the common target antigen in GD, GO and PTM, with evidence for receptor transcripts and/or protein in these locations. The aim of this study has been to investigate whether receptor protein is present in the pretibial tissues. Skin biopsies were obtained from two patients with PTM and two normal subjects without thyroid disease. A portion of each sample was fixed to produce semi-thin sections for Toluidine Blue or Periodic Acid Schiff (PAS) staining. The remainder was snap frozen to generate cryostat sections for immunohistochemical analysis using three monoclonal antibodies against TSH-R. In the skin from the two patients suffering from PTM, the dermis was infiltrated by inflammatory cells (lymphocytes, B cells, macrophages, mast cells) and adipocytes. The collagen fibers were dissociated by edema and by the accumulation of a PAS-positive material. Immunodetection of TSH-R produced positive staining on cells localized in the dermis, beneath the epidermis or close to the hypodermis. These cells were elongated and resembled fibroblasts. No immunoreactivity was observed in the dermis from control patients without thyroid disease. In conclusion, we have evidence for TSH-R immunoreactivity in the pretibium of patients with GD, GO and PTM. Further studies are needed to unambiguously identify the positive cells and determine whether the reactivity is due to the receptor itself or to a cross-reacting protein.  (+info)

Intravenous immunoglobulins control scleromyxoedema. (7/96)

BACKGROUND: Scleromyxoedema is a variant of papular mucinosis affecting the skin and internal organs. The different therapeutic approaches proposed for scleromyxoedema are still unsatisfactory. Intravenous immunoglobulin (IVIg) has been successfully employed in the treatment of connective tissue diseases and vasculitides. PATIENTS: The successful treatment of three cases of scleromyxoedema with IVIg is reported here. CONCLUSIONS: The relatively low risk of the drug and the high effectiveness seen in three patients suggest that IVIg is a new treatment potentially useful in scleromyxoedema.  (+info)

Myxedema accompanied by huge portal-systemic shunt without portal hypertension. (8/96)

A 43-year-old woman with a huge portal-systemic shunt accompanied by myxedema showed slow speech and behavior. Several imaging studies revealed a bold portal-systemic shunt from the splenic vein to the left renal vein. In addition, hypothyroidism caused by chronic thyroiditis was diagnosed, and synthesized thyroxine replacement was effective for the symptoms. However, the serum ammonia and indocyanin green retention remained in the abnormal range, nevertheless the portal vein pressure was normal and findings of liver cirrohsis were not recognized histologically. Surgical shunt closure was performed, resulting in normalized serum ammonia levels and serum branched chain amino acids /aromatic amino acids ratio, and improvement of the ammonia tolerance test.  (+info)

Myxedema is not a term used in modern medicine to describe a specific medical condition. However, historically, it was used to refer to the severe form of hypothyroidism, a condition characterized by an underactive thyroid gland that doesn't produce enough thyroid hormones. In hypothyroidism, various body functions slow down, which can lead to symptoms such as fatigue, weight gain, cold intolerance, constipation, and dry skin.

Myxedema specifically refers to the physical signs of severe hypothyroidism, including swelling (edema) and thickening of the skin, particularly around the face, hands, and feet, as well as a puffy appearance of the face. The term myxedema coma was used to describe a rare but life-threatening complication of long-standing, untreated hypothyroidism, characterized by altered mental status, hypothermia, and other systemic manifestations.

Nowadays, healthcare professionals use more precise medical terminology to describe these conditions, such as hypothyroidism or myxedematous edema, rather than the outdated term myxedema.

Leg dermatoses is a general term that refers to various skin conditions affecting the legs. This can include a wide range of inflammatory, infectious, or degenerative diseases that cause symptoms such as redness, itching, scaling, blistering, or pigmentation changes on the leg skin. Examples of specific leg dermatoses include stasis dermatitis, venous eczema, contact dermatitis, lichen planus, psoriasis, and cellulitis among others. Accurate diagnosis usually requires a thorough examination and sometimes a biopsy to determine the specific type of dermatosis and appropriate treatment.

A coma is a deep state of unconsciousness in which an individual cannot be awakened, cannot respond to stimuli, and does not exhibit any sleep-wake cycles. It is typically caused by severe brain injury, illness, or toxic exposure that impairs the function of the brainstem and cerebral cortex.

In a coma, the person may appear to be asleep, but they are not aware of their surroundings or able to communicate or respond to stimuli. Comas can last for varying lengths of time, from days to weeks or even months, and some people may emerge from a coma with varying degrees of brain function and disability.

Medical professionals use various diagnostic tools and assessments to evaluate the level of consciousness and brain function in individuals who are in a coma, including the Glasgow Coma Scale (GCS), which measures eye opening, verbal response, and motor response. Treatment for coma typically involves supportive care to maintain vital functions, manage any underlying medical conditions, and prevent further complications.

Hypothyroidism is a medical condition where the thyroid gland, which is a small butterfly-shaped gland located in the front of your neck, does not produce enough thyroid hormones. This results in a slowing down of the body's metabolic processes, leading to various symptoms such as fatigue, weight gain, constipation, cold intolerance, dry skin, hair loss, muscle weakness, and depression.

The two main thyroid hormones produced by the thyroid gland are triiodothyronine (T3) and thyroxine (T4). These hormones play crucial roles in regulating various bodily functions, including heart rate, body temperature, and energy levels. In hypothyroidism, the production of these hormones is insufficient, leading to a range of symptoms that can affect multiple organ systems.

Hypothyroidism can be caused by several factors, including autoimmune disorders (such as Hashimoto's thyroiditis), surgical removal of the thyroid gland, radiation therapy for neck cancer, certain medications, and congenital defects. Hypothyroidism is typically diagnosed through blood tests that measure levels of TSH (thyroid-stimulating hormone), T3, and T4. Treatment usually involves taking synthetic thyroid hormones to replace the missing hormones and alleviate symptoms.

Hypothermia is a medically defined condition where the core body temperature drops below 35°C (95°F). It is often associated with exposure to cold environments, but can also occur in cases of severe illness, injury, or immersion in cold water. Symptoms may include shivering, confusion, slowed heart rate and breathing, and if not treated promptly, can lead to unconsciousness, cardiac arrest, and even death.

Graves' disease is defined as an autoimmune disorder that leads to overactivity of the thyroid gland (hyperthyroidism). It results when the immune system produces antibodies that stimulate the thyroid gland, causing it to produce too much thyroid hormone. This can result in a variety of symptoms such as rapid heartbeat, weight loss, heat intolerance, and bulging eyes (Graves' ophthalmopathy). The exact cause of Graves' disease is unknown, but it is more common in women and people with a family history of the disorder. Treatment may include medications to control hyperthyroidism, radioactive iodine therapy to destroy thyroid tissue, or surgery to remove the thyroid gland.

Thyroxine (T4) is a type of hormone produced and released by the thyroid gland, a small butterfly-shaped endocrine gland located in the front of your neck. It is one of two major hormones produced by the thyroid gland, with the other being triiodothyronine (T3).

Thyroxine plays a crucial role in regulating various metabolic processes in the body, including growth, development, and energy expenditure. Specifically, T4 helps to control the rate at which your body burns calories for energy, regulates protein, fat, and carbohydrate metabolism, and influences the body's sensitivity to other hormones.

T4 is produced by combining iodine and tyrosine, an amino acid found in many foods. Once produced, T4 circulates in the bloodstream and gets converted into its active form, T3, in various tissues throughout the body. Thyroxine has a longer half-life than T3, which means it remains active in the body for a more extended period.

Abnormal levels of thyroxine can lead to various medical conditions, such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid). These conditions can cause a range of symptoms, including weight gain or loss, fatigue, mood changes, and changes in heart rate and blood pressure.

... is more common in women than in men. Myxedema can occur in: Hyperthyroidism, associated with pretibial myxedema and ... One manifestation of myxedema occurring in the lower limb is pretibial myxedema, a hallmark of Graves disease, an autoimmune ... Myxedema (British English: myxoedema) is a term used synonymously with severe hypothyroidism. However, the term is also used to ... Myxedema can also occur in Hashimoto thyroiditis and other long-standing forms of hypothyroidism. The word myxedema originates ...
Myxedema, although included in the name, is not necessarily seen in myxedema coma.[citation needed] Coma is also not ... precipitates the myxedema coma state, usually in the elderly. Primary symptoms of myxedema coma are altered mental status and ... Myxedema coma is most common in people 60 years old and older and is most common in the winter months when hypothermia is more ... The incidence of myxedema coma has been reported to be 0.22 per 1000000 per year but the data is limited and especially lacking ...
"Myxedema" is a synonym with severe hypothyroidism. It was first described in 1888 by "the Committee of the Clinical Society of ... Myxedema psychosis is a relatively uncommon consequence of hypothyroidism, such as in Hashimoto's thyroiditis or in patients ... Myxedematous psychosis, more commonly referred to as the myxedema madness is manifested through hypothyroidism which is a ... Parikh, Nimesh; Sharma, Prateek; Parmar, Chirag (January 2014). "A Case Report on Myxedema Madness: Curable Psychosis". Indian ...
... (myxoedema in British English, also known as Graves' dermopathy, thyroid dermopathy, Jadassohn-Dösseker ... Pretibial myxedema". Can Fam Physician. 54 (3): 357, 369. PMC 2278349. PMID 18337527. Dennis, Mark; Bowen, William Talbot; Cho ... Many cases of pretibial myxedema, particularly cases that are mild, can be managed without specific pharmacologic treatment; ... Fatourechi V (2005). "Pretibial myxedema: pathophysiology and treatment options". Am J Clin Dermatol. 6 (5): 295-309. doi: ...
... , also known as Jadassohn-Dosseker syndrome, is thought to represent a pure nodular variant of lichen ...
Wilder, Russell M. (1926). "Hyperthyroidism, Myxedema and Diabetes". Archives of Internal Medicine. 38 (6): 736-760. doi: ...
"The protein content of the cerebrospinal fluid in myxedema" (1928, with Willard Owen Thompson, Phebe K. Thompson, and Mary ... "The protein content of the cerebrospinal fluid in myxedema." The Journal of Clinical Investigation 6, no. 2 (1928): 251-255. ... Thompson, Willard Owen (1929-09-01). "The Cerebrospinal Fluid in Myxedema". Archives of Internal Medicine. 44 (3): 368. doi: ... Elizabeth Dailey) "The Cerebrospinal Fluid in Myxedema" (1929, with Willard Owen Thompson, Phebe K. Thompson, and Mary ...
Brissaud's infantilism - infantile myxedema (hypothyroidism). Described in 1907. Brissaud's reflex - a contraction of the ...
Mumford PB, Barber HW (April 1943). "Lichen Ruber Moniliformis (Morbus Moniliformis Lichenoides; Myxoedema Moniliforme.)". Proc ...
The status of the heart in myxedema. Am. Heart Jr., 1925; i: 67-72. Amberg, S. and F.A. Willius. Auricular Flutter with ...
ISBN 978-1-84792-062-1 Heinrich, T. W.; Grahm, G. (2003). "Hypothyroidism Presenting as Psychosis: Myxedema Madness Revisited ...
Myxedema coma Euthyroid sick syndrome Pokhrel, Binod; Aiman, Wajeeha; Bhusal, Kamal (2022-10-06). "Thyroid Storm". StatPearls ...
with H. G. Lloyd-Thomas: Cohen, R. D.; Lloyd-Thomas, H. G. (6 August 1966). "Exercise electrocardiogram in myxoedema". Br Med J ... COHEN RD (October 1963). "Water and electrolyte metabolism during the treatment of myxoedema". Clinical Science. 25: 293-304. ...
The eponym "Woltman's sign of myxedema" was first published in 1956 at the time of Woltman's retirement. Houston CS (1958). " ... Woltman's sign (also called Woltman's sign of hypothyroidism or, in older references, myxedema reflex) is a delayed relaxation ... Chaney WC (1924). "Tendon reflexes in myxedema: a valuable aid in diagnosis". Journal of the American Medical Association. 82 ( ... "The Origin of Woltman's Sign of Myxedema (P05. 256)". Neurology. 80 (7 Supplement): P05-256. v t e (Articles with short ...
DNP cannot substitute for thyroid hormone in myxedema. Information about pharmacokinetics and pharmacodynamics of DNP in humans ...
It is also seen in measles, tetanus and myxedema. It can also be found in subjects with respiratory alkalosis, for example as a ...
The signs of myxedema can be seen in dogs, with prominence of skin folds on the forehead, and cases of myxedema coma are ... Myxedema coma can be the first presentation of hypothyroidism. People with myxedema coma typically have a low body temperature ... Myxedema coma is a rare but life-threatening state of extreme hypothyroidism. It may occur in those with established ... The first cases of myxedema were recognized in the mid-19th century (the 1870s), but its connection to the thyroid was not ...
Allostatic overload may result in wasting syndrome and myxedema coma. Thyroid storm, though, represents allostatic failure, ...
... may also be used for myxedema coma because of its quicker onset of action when compared to levothyroxine. Use for ... It is most commonly used to treat hypothyroidism and myxedema coma. It can be taken by mouth or by injection into a vein. Side ...
Another cutaneous form of edema is myxedema, which is caused by increased deposition of connective tissue. In myxedema (and a ... In myxedema, this is due to an increase in hydrophilic carbohydrate-rich molecules (perhaps mostly hyaluronin) deposited in the ... It is associated with such conditions as lymphedema, lipedema, and myxedema. Edema caused by malnutrition defines kwashiorkor, ...
"A case of myxoedema supervening on Graves' disease". Transact. Of the Clin. Soc. Of London. 33: 189-192. 1900. Pasteur, W. ( ...
He began to take a special interest in obesity, diabetes, and myxedema. He published on the influence of the thyroid on ...
The latter explains the reason of the myxedema finding during Graves disease. In addition, it has also been found to be ...
Myxedema is first treated successfully, by George Redmayne Murray using thyroid extract. The earliest recorded attempt at hip ...
Houston, CS (1958). "The diagnostic importance of the myxoedema reflex (Woltman's sign)". Canadian Medical Association Journal ...
... hyposecretion causes cretinism in infants and myxoedema in adults. Hyperparathyroidism results in hypercalcemia and its effects ...
The life history of the first case of myxoedema treated by thyroid extract. Br Med J 1920;i:359-60. Burgess AM. Myxedema-- ... George Redmayne Murray of the United Kingdom first described treatment of myxedema with thyroid extract in 1891, and published ... a description of long-term successful treatment (28 years) of a patient with myxedema (severe hypothyroidism) in 1920 His ...
Graves' ophthalmopathy (protrusion of one or both eyes) Pretibial myxedema Cardiovascular features may include hypertension, ... Neurological seizures, neuropathy from nerve entrapment by lesions of pretibial myxedema, and hypokalemic periodic paralysis ... goitre and pretibial myxedema. These clinical manifestations can involve virtually every system in the body. The mechanisms ...
Some forms of hypothyroidism can result in myxedema and severe cases can result in myxedema coma. Hypothyroidism is managed ... In the nineteenth century numerous authors described both cretinism and myxedema, and their relationship to the thyroid. ...
Myxedema coma is a rare but serious aspect of the disease that is a medical emergency. Hypoadrenocorticism, also known as ...
Myxedema is more common in women than in men. Myxedema can occur in: Hyperthyroidism, associated with pretibial myxedema and ... One manifestation of myxedema occurring in the lower limb is pretibial myxedema, a hallmark of Graves disease, an autoimmune ... Myxedema (British English: myxoedema) is a term used synonymously with severe hypothyroidism. However, the term is also used to ... Myxedema can also occur in Hashimoto thyroiditis and other long-standing forms of hypothyroidism. The word myxedema originates ...
Pretibial myxedema (PTM) or, more appropriately, thyroid dermopathy is a term used to describe localized lesions of the skin ... encoded search term (Pretibial Myxedema) and Pretibial Myxedema What to Read Next on Medscape ... Pretibial Myxedema. Updated: Jul 08, 2020 * Author: Ranjodh Singh Gill, MD, FACP, CCD; Chief Editor: Dirk M Elston, MD more... ... Nodular foot myxedema masquerading as lymphedema. Plast Reconstr Surg Glob Open. 2015 Jul. 3(7):e457. [QxMD MEDLINE Link]. [ ...
Myxedema Heart. Wilbur E. Flannery, M.D. and A. Carlton Ernstene, M.D. ...
encoded search term (Hypothyroidism and Myxedema Coma) and Hypothyroidism and Myxedema Coma What to Read Next on Medscape ... Hypothyroidism and Myxedema Coma Treatment & Management. Updated: May 12, 2021 * Author: Erik D Schraga, MD; Chief Editor: ... Severe angioedema in myxedema coma: a difficult airway in a rare endocrine emergency. Am J Emerg Med. 2009 Oct. 27(8):1021.e1-2 ... Most patients with myxedema coma respond to passive rewarming measures such as blankets and removal of cold or wet clothing; ...
... , also known as localized myxedema or thyroid dermopathy, is an uncommon finding in autoimmune thyroid ... Pretibial myxedema See also in: Cellulitis DDx. Print Images (46) Contributors: Amy Kalowitz Bieber MD, Noah Craft MD, PhD, ... Pretibial myxedema may occur in any age group and either sex but is more common in older adults and women. There are rare case ... Pretibial myxedema may exist in various clinical forms. The nonpitting type is most common, followed by nodular and plaquelike ...
J Hoffman, DA Reaveley, D Jackson, CLE Roux, J Alaghband-Zadeh; Plasma Homocysteine Concentration in Myxoedema. Clin Sci (Lond) ...
Learn about myxedema, a rare complication of hypothyroidism. Identify the most serious symptoms and their causes at 10FAQ. ... Myxedema comas commonly have specific events beforehand that seem related to the coma. This event may be an infection or ... Myxedema Coma: Diagnosis and Treatment. American Family Physician, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/ ... Patients with myxedema symptoms may be facing a severe health issue and should consult a qualified physician right away. ...
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myxedema answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, Android, ... pretibial myxedema. pretibial myxedema. pretibial myxedema. Infiltration of the skin of the anterior legs by ... PRETIBIAL MYXEDEMA Citation. Venes, Donald, editor. "Myxedema." Tabers Medical Dictionary, 24th ed., F.A. Davis Company, 2021 ... myx- + edema] The clinical and metabolic manifestations of hypothyroidism in adults, adolescents, and children. myxedematous ( ...
MYXEDEMA COMA. Myxedema coma is a rare complication of hypothyroidism. The incidence is greater in women than men, and ... All patients who develop myxedema are hypothyroid, but not all hypothyroid patients have myxedema. Hypothyroidism is a graded ... Myxedema coma is a life-threatening expression of hypothyroidism in its most severe form. It occurs most often during the ... The diagnosis of myxedema coma may easily be made in a patient who presents with the previously described general appearance ...
Myxedema Symptom Checker: Possible causes include Hashimoto Thyroiditis. Check the full list of possible causes and conditions ... Possible Causes for Myxedema Hashimoto Thyroiditis. Abstract Myxedema coma (MC) is a rare, but often fatal endocrine emergency. ... Myxedema Myxedema (hypothyroidism) belongs to a type of goiter that is caused by the reduced formation of thyroid hormone. [ ... Myxedema coma can result in death. Complications: Myxedema coma, the most severe form of hypothyroidism, is rare. [uclahealth. ...
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encoded search term (Hypothyroidism and Myxedema Coma) and Hypothyroidism and Myxedema Coma What to Read Next on Medscape ... Hypothyroidism and Myxedema Coma Differential Diagnoses. Updated: Dec 11, 2015 * Author: Erik D Schraga, MD; Chief Editor: ... Severe angioedema in myxedema coma: a difficult airway in a rare endocrine emergency. Am J Emerg Med. 2009 Oct. 27(8):1021.e1-2 ... Beynon J, Akhtar S, Kearney T. Predictors of outcome in myxoedema coma. Crit Care. 2008. 12(1):111. [QxMD MEDLINE Link]. [Full ...
Myxedema Coma. Myxedema coma is a life-threatening emergency characterized by poor circulation and hypometabolism, and may ... Use of oral thyroid hormone drug products is not recommended to treat myxedema coma. Administer thyroid hormone products ... formulated for intravenous administration to treat myxedema coma.. Acute Adrenal Crisis In Patients With Concomitant Adrenal ...
Myxedema coma, the most severe form of hypothyroidism, is rare. It may be caused by an infection, illness, exposure to cold, or ... Severe hypothyroidism may result in myxedema coma, in which a drastic drop in the metabolic rate causes decreased vital signs, ... Hypothyroidism (myxedema) causes facial puffiness, extremity edema, and weight gain. Signs and symptoms of hyperthyroidism ( ... A female client with hypothyroidism (myxedema) is receiving levothyroxine (Synthroid), 25 mcg P.O. daily. Which finding should ...
... May 1, 2004. Eugene Wang, MD. Peter Petropoulos, MD ... Pericardialeffusion is a common findingin myxedema, occurring in up to onethird of all cases. ...
We diagnosed myxedema coma and started treatment with intravenous T3.. She responded dramatically with improvement in level of ... BACKGROUND: Myxedema coma is the extreme manifestation of hypothyroidism, typically seen in patients with severe biochemical ... REVIEW: "subclinical hypothyroidism" patient with myxedema coma. Heres an example of the problem with judging thyroid hormone ... CONCLUSIONS: To the best of our knowledge this is the first report of myxedema coma in a patient with subclinical ...
Cirrhosis is defined histologically as a diffuse hepatic process characterized by fibrosis and the conversion of normal liver architecture into structurally abnormal nodules. The progression of liver injury to cirrhosis may occur over weeks to years.
Cirrhosis is defined histologically as a diffuse hepatic process characterized by fibrosis and the conversion of normal liver architecture into structurally abnormal nodules. The progression of liver injury to cirrhosis may occur over weeks to years.
Myxedema. This is a rare, life-threatening condition. Symptoms are intense sensitivity to cold and drowsiness or severe ...
Congenital myxedema. *Cretinism. Additional Information & Resources. Genetic Testing Information. *Genetic Testing Registry: ...
Myxedema madness: An intriguing case of depression in hypothyroidism. / Patil, Navin; Rao, Karthik N.; Balaji, O. et al. In: ... Myxedema madness: An intriguing case of depression in hypothyroidism. Navin Patil, Karthik N. Rao, O. Balaji, Humera Naaz, ... Myxedema madness: An intriguing case of depression in hypothyroidism. Asian Journal of Pharmaceutical and Clinical Research. ... Myxedema madness : An intriguing case of depression in hypothyroidism. In: Asian Journal of Pharmaceutical and Clinical ...
Lecture notes on Myxoedema, PRevious year question of GPAT on myxoedema, Previous year question of NEET on myxoedema, PRevious ... UGC NET JRF Exam Causes of myxoedema, Clinical features of myxoedema, Definition of myxoedema, Important question for NEET on ... Previous year question of UGC NET on myxoedema, Previous year question on myxoedema, Symptoms of myxoedema, Treatment of ... The term myxoedema is applied to hypothyroidism in the older child or in the adults. 1.] The term myxoedema suggests non - ...
Pericardial effusion is the presence of an abnormal amount of and/or an abnormal character to fluid in the pericardial space. It can be caused by a variety of local and systemic disorders, or it may be idiopathic.
... myxedema, cretinism, goiter) Buy online at Tokyo Medical at best price. ... Thyradin-S tablets 50 mcg for thyroid hormone therapy (levothyroxine, hypothyroidism, myxedema, cretinism, goiter). Product ... Thyradin-S tablets 50 mcg for thyroid hormone therapy (levothyroxine, hypothyroidism, myxedema, cretinism, goiter) ... myxedema, and cretinism. Its imperative for your physician to determine the precise dosage and treatment duration, which might ...
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Myxedema. Initial: 5 mcg PO qDay; may increase by 5-10 mcg/day q1-2Weeks ...
Myxedema. *Severe hypothyroidism can lead to a condition called myxedema, characterized by dry, thickened skin and coarse ... MYXEDEMA. NORMAL LEVELS. THYROXINE. MENTAL RETARDATION. HORMONE PRODUCTION. SEVERE FORM. CONDITION CALLED. HYPOTHYROIDISM ... The most severe form of hypothyroidism is myxedema, a medical emergency.. Condition Called. *A condition called secondary ... Myxedema coma, the most severe form of hypothyroidism, is rare. (Web site). ...
Myxedema coma. *Myxedema coma is a life-threatening emergency characterized by poor circulation and hypometabolism, and may ... Myxedema Coma. 300-500 mcg IV once, THEN 50-100 mcg qDay until patient is able to tolerate oral administration; may consider ... Treat myxedema coma with IV thyroid products Acute adrenal crisis in patients with concomitant adrenal insufficiency. *Thyroid ... Use of oral thyroid hormone drug products is not recommended to treat myxedema coma ...
  • Myxedema coma is rare but often fatal. (wikipedia.org)
  • If myxedema coma is suspected on clinical impression, start IV thyroid hormone treatment. (medscape.com)
  • With a diagnosis of myxedema coma, initiate hormonal therapy. (medscape.com)
  • Myxedema coma may lead to profound hemodynamic instability and airway compromise. (medscape.com)
  • Emergency physicians should anticipate a potentially difficult airway in patients with myxedema coma. (medscape.com)
  • For patients with myxedema coma, consult a critical care intensivist regarding admission to an ICU and optimization treatment. (medscape.com)
  • Myxedema and Coma (Severe Hypothyroidism). (medscape.com)
  • A diagnostic scoring system for myxedema coma. (medscape.com)
  • Severe angioedema in myxedema coma: a difficult airway in a rare endocrine emergency. (medscape.com)
  • Ono Y, Ono S, Yasunaga H, Matsui H, Fushimi K, Tanaka Y. Clinical characteristics and outcomes of myxedema coma: Analysis of a national inpatient database in Japan. (medscape.com)
  • Myxedema Coma: Diagnosis and Treatment. (10faq.com)
  • One of the rarest but most serious symptoms of myxedema is unresponsiveness and coma. (10faq.com)
  • Myxedema comas commonly have specific events beforehand that seem related to the coma. (10faq.com)
  • Myxedema coma is a life-threatening expression of hypothyroidism in its most severe form. (emjournal.net)
  • Beynon J, Akhtar S, Kearney T. Predictors of outcome in myxoedema coma. (medscape.com)
  • Hehrmann R. [Coma in myxedema--a rare complication of hypothyroidism. (medscape.com)
  • Thyrotoxic crisis and myxedema coma. (medscape.com)
  • Myxedema coma, the most severe form of hypothyroidism, is rare. (rnpedia.com)
  • Only including T3 in her therapy saved her from death by hypothyroidism, since she entered the extremely hypothyroid state of myxoedema coma. (thyroidpatients.ca)
  • BACKGROUND: Myxedema coma is the extreme manifestation of hypothyroidism, typically seen in patients with severe biochemical hypothyroidism. (thyroidpatients.ca)
  • We describe a patient with subclinical hypothyroidism who developed clinical manifestations of myxedema coma. (thyroidpatients.ca)
  • We diagnosed myxedema coma and started treatment with intravenous T3. (thyroidpatients.ca)
  • CONCLUSIONS: To the best of our knowledge this is the first report of myxedema coma in a patient with subclinical hypothyroidism. (thyroidpatients.ca)
  • Levothyroxine is used in adults to treat myxedema coma. (everydayhealth.com)
  • Untreated myxedema coma has a poor prognosis and a high mortality rate, particularly in old age. (igi-global.com)
  • One manifestation of myxedema occurring in the lower limb is pretibial myxedema, a hallmark of Graves disease, an autoimmune form of hyperthyroidism. (wikipedia.org)
  • Myxedema can occur in the lower leg (pretibial myxedema) and behind the eyes (exophthalmos). (wikipedia.org)
  • One of the hallmarks of Grave's disease is pretibial myxedema, myxedema of the lower limb. (wikipedia.org)
  • Myxedema can occur in: Hyperthyroidism, associated with pretibial myxedema and exophthalmos. (wikipedia.org)
  • Pretibial myxedema can occur in 1-4% of patients with Graves' disease, a cause of hyperthyroidism. (wikipedia.org)
  • Pretibial myxedema (PTM) or, more appropriately, thyroid dermopathy, is a term used to describe localized lesions of the skin resulting from the deposition of hyaluronic acid, usually as a component of thyroid disease. (medscape.com)
  • Pretibial myxedema (PTM) occurs as a result of the deposition of hyaluronic acid in the dermis and subcutis. (medscape.com)
  • Pretibial myxedema (PTM) occurs in 0.5-4.3% of patients with Graves disease. (medscape.com)
  • Pretibial myxedema (PTM) is primarily of cosmetic concern and rarely causes significant morbidity. (medscape.com)
  • Pretibial myxedema, also known as localized myxedema or thyroid dermopathy, is an uncommon finding in autoimmune thyroid disease and most commonly affects those with Graves disease . (logicalimages.com)
  • Pretibial myxedema may exist in various clinical forms. (logicalimages.com)
  • The pretibial region is most commonly involved because it is thought to be related to local cues, evidenced by development of pretibial myxedema in grafted skin. (logicalimages.com)
  • Pretibial myxedema may occur in any age group and either sex but is more common in older adults and women. (logicalimages.com)
  • Myxedema (British English: myxoedema) is a term used synonymously with severe hypothyroidism. (wikipedia.org)
  • Patients with myxedema symptoms may be facing a severe health issue and should consult a qualified physician right away. (10faq.com)
  • Myxedema is the name given to very severe hypothyroidism. (msdmanuals.com)
  • Myxedema is a manifestation of severe hypothyroidism, and when affecting the larynx it constitutes a rare cause of upper airway obstruction. (bvsalud.org)
  • Se encuentra asociado a diabetes mellitus en la mayoría de los casos, preferentemente en mujeres, y suele revolverse espontáneamente entre 6 meses y 2 años. (bvsalud.org)
  • It is often possible to diagnose myxedema on clinical grounds alone. (wikipedia.org)
  • Hence, we report a case of hypertensive patient on medications started with antidepressants and antipsychotics after being diagnosed of depression but was found to be resistant to psychiatric medications and later successfully treated with levothyroxine for underlying hypothyroidism with myxedema. (manipal.edu)
  • The atypical aspect of the stenosis along with a thyroid goiter and a positive screening for neonatal hypothyroidism allowed the diagnosis of laryngeal myxedema. (bvsalud.org)
  • However, not all thyroid issues result in myxedema, so being able to identify the symptoms is critical. (10faq.com)
  • Myxedema can be a life-threatening condition, and its symptoms can rapidly progress from troubling to extremely serious. (10faq.com)
  • Thyradin S tablets serve as an option for addressing insufficiencies in thyroid hormones, encompassing conditions like hypothyroidism, hypophyseal disorders, myxedema, and cretinism. (japanese-medicines.com)
  • Myxedema is known to occur in various forms of hypothyroidism, including Graves disease. (wikipedia.org)
  • RÉSUMÉ La première description des pathologies thyroïdiennes, telles qu'on les connaît aujourd'hui, a été celle de la maladie de Graves par Caleb Parry en 1786, mais la pathogenèse de l'affection thyroïdienne n'a pas été découverte avant 1882-1886. (who.int)
  • 2021. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/761940/all/myxedema. (unboundmedicine.com)
  • Myxedema is a complication of extended, untreated hypothyroidism, which is caused by the thyroid gland's failure to produce enough of the hormones the body needs. (10faq.com)
  • The term myxoedema is applied to hypothyroidism in the older child or in the adults. (gpatindia.com)
  • Myxedema can also occur in Hashimoto thyroiditis and other long-standing forms of hypothyroidism. (wikipedia.org)
  • When this happens, patients have an advanced stage of myxedema that may be life-threatening. (10faq.com)
  • All patients who develop myxedema are hypothyroid, but not all hypothyroid patients have myxedema. (emjournal.net)
  • Myxedema describes a specific form of cutaneous and dermal edema secondary to increased deposition of connective tissue components. (wikipedia.org)
  • In this latter sense, myxedema refers to deposition of mucopolysaccharides in the dermis, which results in swelling of the affected area. (wikipedia.org)
  • The term myxedema refers to this particular presentation of hypothyroidism. (emjournal.net)
  • The reaction time myxoedema. (nih.gov)
  • myxedema, physiological reaction to lack of sufficient thyroid hormone (hypothyroidism) in the adult. (britannica.com)
  • 1.] The term myxoedema suggests non - pitting oedema due to the accumulation of hydrophilic mucopolysaccharides in the ground substances of dermis and other tissues. (gpatindia.com)
  • Thomas Curling first described hyopothyroidism (myxoedema) in 1850 and the cause and suitable treatment were established after 1883. (who.int)
  • Myxedema was first treated successfully in 1891 when George Redmayne Murray diagnosed a 46-year-old woman with the disease. (wikipedia.org)
  • We present a case of laryngeal myxedema in a newborn causing subglottic stenosis. (bvsalud.org)
  • Myxedema is more common in women than in men. (wikipedia.org)
  • Pericardialeffusion is a common findingin myxedema, occurring in up to onethird of all cases. (patientcareonline.com)
  • Myxedema (British English: myxoedema) is a term used synonymously with severe hypothyroidism. (wikipedia.org)
  • Myxedema can also occur in Hashimoto thyroiditis and other long-standing forms of hypothyroidism. (wikipedia.org)
  • Myxedema is known to occur in various forms of hypothyroidism, including Graves disease. (wikipedia.org)
  • Myxoedema is responsible for the thickening of the tongue and the laryngeal and pharyngeal mucous membranes, which results in thick slurred speech and hoarseness, both of which are seen commonly in hypothyroidism. (wikipedia.org)
  • Severe hypothyroidism can be associated with "myxedema heart" characterized by relative bradycardia and pericardial effusion. (medscape.com)
  • The incidence of pericardial effusion in hypothyroidism is 3% in the early mild stage and up to 80% in patients with myxedema. (medscape.com)
  • Myxedema is a complication of extended, untreated hypothyroidism, which is caused by the thyroid gland's failure to produce enough of the hormones the body needs. (10faq.com)
  • Myxedema coma typically presents as decreased mental status and hypothermia in a patient with either chronic, severe hypothyroidism or any form of hypothyroidism in the setting of a significant physiological stressor (infection, MI, sedative medications/opioids). (openanesthesia.org)
  • If the patient has primary hypothyroidism (majority of myxedema coma cases), TSH will be high and free T4 will be low. (openanesthesia.org)
  • Psychotic symptoms associated with hypothyroidism, also known as "myxedema psychosis," are a treatable cause of psychosis often associated with complete recovery. (medscape.com)
  • Myxedema is a term use to describe the advanced stage of hypothyroidism, where the thyroid gland fails to produce sufficient thyroid hormones. (healthsaf.com)
  • Myxedema is primarily caused by untreated or poorly managed hypothyroidism. (healthsaf.com)
  • Conditions like Hashimoto's thyroiditis can lead to hypothyroidism and, subsequently, myxedema. (healthsaf.com)
  • Hypothyroidism and myxedema can occur in areas with low dietary iodine intake. (healthsaf.com)
  • Treatment for thyroid disorders, including surgery and radiation therapy, can sometimes result in hypothyroidism and myxedema. (healthsaf.com)
  • Managing myxedema involves addressing the underlying hypothyroidism. (healthsaf.com)
  • Myxedema Coma -- this is a rare complication of severe Hypothyroidism . (ecureme.com)
  • The injectable form is also indicated to be used to treat a complication of severe hypothyroidism called myxedema coma. (rxwiki.com)
  • The injectable form of liothyronine is used as treatment for a complication of severe hypothyroidism called myxedema coma. (rxwiki.com)
  • Myxedema is the name given to very severe hypothyroidism. (msdmanuals.com)
  • Complications of untreated hypothyroidism range from a goiter to a rare condition called myxedema. (everydayhealth.com)
  • 5. Disturbances of hormone: Common in Diabetics Myxedema (Hypothyroidism) and in certain pituitary disorders of brain and tumors of adrenal glands. (selfgrowth.com)
  • Severe hypothyroidism can evolve into a complication known as myxedema crisis or myxedema coma - a rare, but known complication. (cancer.org)
  • A case of myxœdema. (nih.gov)
  • In the first case of myxœdema in which I employed the thyroid treatment, I gave the raw gland and I gave far too large a dose. (oneradionetwork.com)
  • One manifestation of myxedema occurring in the lower limb is pretibial myxedema, a hallmark of Graves disease, an autoimmune form of hyperthyroidism. (wikipedia.org)
  • Myxedema can occur in the lower leg (pretibial myxedema) and behind the eyes (exophthalmos). (wikipedia.org)
  • One of the hallmarks of Grave's disease is pretibial myxedema, myxedema of the lower limb. (wikipedia.org)
  • Myxedema can occur in: Hyperthyroidism, associated with pretibial myxedema and exophthalmos. (wikipedia.org)
  • Pretibial myxedema can occur in 1-4% of patients with Graves' disease, a cause of hyperthyroidism. (wikipedia.org)
  • Lymphedema should be included in the differential diagnosis of pretibial myxedema, particularly for presentation in the foot. (medscape.com)
  • Nair PA, Mishra A, Chaudhary A. Pretibial myxedema associated with euthyroid Hashimoto's thyroiditis: a case report. (medscape.com)
  • Schwartz KM, Fatourechi V, Ahmed DD, Pond GR. Dermopathy of Graves' disease (pretibial myxedema): long-term outcome. (medscape.com)
  • Thyrotrophin receptor antibody characteristics in a woman with long-standing Hashimoto's who developed Graves' disease and pretibial myxoedema. (medscape.com)
  • Lan C, Chen W, Zhao J, Li C, Mei X, Hu J. Prevalence and clinical characteristics of pretibial myxedema in Chinese outpatients with thyroid diseases. (medscape.com)
  • Pretibial myxedema without ophthalmopathy: an initial presentation of Graves' disease. (medscape.com)
  • Sendhil Kumaran M, Dutta P, Sakia U, Dogra S. Long-term follow-up and epidemiological trends in patients with pretibial myxedema: an 11-year study from a tertiary care center in northern India. (medscape.com)
  • Xu Y, Ma R, Cai Y, Zheng X. Response to topical halcinonide following fractional carbon dioxide laser pretreatment in a pretibial myxedema patient. (medscape.com)
  • Lan C, Li C, Chen W, Mei X, Zhao J, Hu J. A randomized controlled trial of intralesional glucocorticoid for treating pretibial myxedema. (medscape.com)
  • Treatment of pretibial myxedema with intralesional immunomodulating therapy. (medscape.com)
  • Successful therapeutic approach in a patient with elephantiasic pretibial myxedema. (medscape.com)
  • Oral pentoxifylline and topical clobetasol propionate ointment in the treatment of pretibial myxoedema, with concomitant improvement of Graves' ophthalmopathy. (medscape.com)
  • This is one of the first case reports demonstrating sustained remission of psychotic symptoms at 6 months in a case of myxedema psychosis treated with minimal antipsychotic medication. (medscape.com)
  • The identification of myxedema psychosis is important owing to the implications on treatment and prognosis of the disorder. (medscape.com)
  • [ 12 ] Others have suggested that the serous pericardial effusion in myxedema is due to accumulation of albumin and other plasma proteins due to extravascular escape and impairment of the lymphatic drainage. (medscape.com)
  • One of the hallmark signs of myxedema is the accumulation of a substance called mucin in the skin and other tissues. (healthsaf.com)
  • We assessed extravascular accumulation of albumin and fluid in primary myxedema by measuring metabolic turnover and transcapillary escape of 131I-labeled human albumin in seven patients. (regionh.dk)
  • The extravascular accumulation of albumin, and presumably of all other plasma proteins, is important in the generalized edema typically found in myxedema. (regionh.dk)
  • Inadequate lymphatic drainage may also explain the formation of exudates in the serous cavities that are well known in myxedema. (regionh.dk)
  • Myxedema causing adynamic ileus, serous effusions, and inappropriate secretion of antidiuretic hormone. (springermedizin.at)
  • The "myxedema heart" was first described by Zondek in 1918 as a syndrome of cardiac alterations, including large cardiac silhouette, electrocardiogram (ECG) changes indicative of a large pericardial effusion including bradycardia, low voltage, nonspecific T-wave abnormalities, and electrical alternans, which reversed with thyroid hormone extract. (medscape.com)
  • Myxedema is a term used to describe a severely underactive thyroid gland in an adult. (healthline.com)
  • 1. Nivolumab induced myxedema crisis. (nih.gov)
  • There are some links there that will also describe the difficulties encountered with myxedema crisis, too - again, this can be very serious, so don't let it go. (cancer.org)
  • Myxedema can also be used to describe skin changes caused by low thyroid hormone levels. (healthline.com)
  • Pre-tibial myxedema: treatment with intralesional corticosteroid. (medscape.com)
  • Thomas Curling first described hyopothyroidism (myxoedema) in 1850 and the cause and suitable treatment were established after 1883. (who.int)
  • At that time, I was deeply interested in the thyroid treatment of myxœdema. (oneradionetwork.com)
  • and I said to myself, if thyroid extract can produce such a remarkable result on the nutrition of the skin in myxœdema, it will probably be useful in the treatment of skin diseases. (oneradionetwork.com)
  • People with myxedema tend to be more sensitive to cold temperatures and may feel excessively cold. (healthsaf.com)
  • P less than 0.01) and a longer mean transit time through the extravascular spaces in primary myxedema than in other states of generalized edema (P less than 0.05). (regionh.dk)
  • Verma S, Rongioletti F, Braun-Falco M, Ruzicka T. Preradial myxedema in a euthyroid male: A distinct rarity. (medscape.com)
  • Myxedema describes a specific form of cutaneous and dermal edema secondary to increased deposition of connective tissue components. (wikipedia.org)
  • We at Healthsaf welcome fresh and unique content related to Myxedema. (healthsaf.com)
  • The editorial team of Healthsaf does not encourage promotional content related to Myxedema. (healthsaf.com)
  • Cet article procède à un examen des principales étapes dans l'histoire de la pathologie de la thyroïde, avec une brève discussion des aspects scientifiques concernant la glande thyroïde qui ont eu une importance historique, et de l'évolution de l'endocrinologie en tant que discipline à part entière. (who.int)
  • Individuals with myxedema frequently experience extreme fatigue and lack energy. (healthsaf.com)