Neoplasms produced from tooth-forming tissues.
Cysts found in the jaws and arising from epithelium involved in tooth formation. They include follicular cysts (e.g., primordial cyst, dentigerous cyst, multilocular cyst), lateral periodontal cysts, and radicular cysts. They may become keratinized (odontogenic keratocysts). Follicular cysts may give rise to ameloblastomas and, in rare cases, undergo malignant transformation.
An immature epithelial tumor of the JAW originating from the epithelial rests of Malassez or from other epithelial remnants of the ENAMEL from the developmental period. It is a slowly growing tumor, usually benign, but displays a marked propensity for invasive growth.
Cancers or tumors of the MAXILLA or MANDIBLE unspecified. For neoplasms of the maxilla, MAXILLARY NEOPLASMS is available and of the mandible, MANDIBULAR NEOPLASMS is available.
Tumors or cancer of the MANDIBLE.
A mixed radiolucent-radiopaque lesion of the jaws with features of both a cyst and a solid neoplasm. It is characterized microscopically by an epithelial lining showing a palisaded layer of columnar basal cells, presence of ghost cell keratinization, dentinoid, and calcification. (Stedman, 25th ed)
Cancer or tumors of the MAXILLA or upper jaw.
A mixed tumor of odontogenic origin, in which both the epithelial and mesenchymal cells exhibit complete differentiation, resulting in the formation of tooth structures. (Jablonski, Illustrated Dictionary of Dentistry, 1982)
A well-differentiated, benign, hamartomatous proliferation of odontogenic epithelium, probably arising from the rests of Malassez.
Most common follicular odontogenic cyst. Occurs in relation to a partially erupted or unerupted tooth with at least the crown of the tooth to which the cyst is attached protruding into the cystic cavity. May give rise to an ameloblastoma and, in rare instances, undergo malignant transformation.
Slow-growing fluid-filled epithelial sac at the apex of a tooth with a nonvital pulp or defective root canal filling.
'Gingival neoplasms' are abnormal, uncontrolled growths of tissue originating from the gingiva, which can be benign (non-cancerous) or malignant (cancerous), often manifesting as swellings, ulcerations, or masses within the oral cavity.
'Jaw diseases' is a broad term referring to various medical conditions affecting the temporomandibular joint, jawbones, or the surrounding muscles, including but not limited to dental disorders, jaw fractures, tumors, infections, and developmental abnormalities.
Maxillary diseases refer to various medical conditions primarily affecting the maxilla (upper jaw) bone, including inflammatory processes, tumors, cysts, or traumatic injuries, which may cause symptoms such as pain, swelling, or functional impairment.
Extraoral body-section radiography depicting an entire maxilla, or both maxilla and mandible, on a single film.
A tooth that is prevented from erupting by a physical barrier, usually other teeth. Impaction may also result from orientation of the tooth in an other than vertical position in the periodontal structures.
Cyst due to the occlusion of the duct of a follicle or small gland.
A benign tumor of fibrous or fully developed connective tissue.
A small, circumscribed, benign tumor of the genital tract, composed of small glandlike spaces lined by flattened or cuboidal mesothelium-like cells. (From Dorland, 27th ed)
A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)
The process of TOOTH formation. It is divided into several stages including: the dental lamina stage, the bud stage, the cap stage, and the bell stage. Odontogenesis includes the production of tooth enamel (AMELOGENESIS), dentin (DENTINOGENESIS), and dental cementum (CEMENTOGENESIS).
Secondary or systemic infections due to dissemination throughout the body of microorganisms whose primary focus of infection lies in the periodontal tissues.
Hereditary disorder consisting of multiple basal cell carcinomas, odontogenic keratocysts, and multiple skeletal defects, e.g., frontal and temporoparietal bossing, bifurcated and splayed ribs, kyphoscoliosis, fusion of vertebrae, and cervicothoracic spina bifida. Genetic transmission is autosomal dominant.
'Mandibular diseases' refer to various medical conditions that primarily affect the structure, function, or health of the mandible (lower jawbone), including but not limited to infections, tumors, developmental disorders, and degenerative diseases.
A benign central bone tumor, usually of the jaws (especially the mandible), composed of fibrous connective tissue within which bone is formed.
An epithelium-lined sac containing fluid; usually found at the apex of a pulp-involved tooth. The lateral type occurs less frequently along the side of the root.
Liquid material found in epithelial-lined closed cavities or sacs.
Localized circumscribed purulent area of inflammation in the periodontal tissue. It is a derivative of marginal periodontitis and commonly associated with suprabony and infrabony pockets and interradicular involvements, in contrast to periapical abscess which is attributable to pulp necrosis.
Surgical insertion of an appliance for the replacement of areas of the mandible.
Tumors or cancer of the MAXILLARY SINUS. They represent the majority of paranasal neoplasms.
The aftermost permanent tooth on each side in the maxilla and mandible.
The proteins that are part of the dental enamel matrix.
Photography of objects viewed under a microscope using ordinary photographic methods.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.
Resorption in which cementum or dentin is lost from the root of a tooth owing to cementoclastic or osteoclastic activity in conditions such as trauma of occlusion or neoplasms. (Dorland, 27th ed)
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Facilities that collect, store, and distribute tissues, e.g., cell lines, microorganisms, blood, sperm, milk, breast tissue, for use by others. Other uses may include transplantation and comparison of diseased tissues in the identification of cancer.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A CELL CYCLE and tumor growth marker which can be readily detected using IMMUNOCYTOCHEMISTRY methods. Ki-67 is a nuclear antigen present only in the nuclei of cycling cells.

Primary intraosseous carcinoma and odontogenic cyst. Three new cases and review of the literature. (1/3)

INTRODUCTION: The Odontogenic Primary Intraosseous Carcinoma (PIOC) are a rare group of malignant tumours with strict clinic and anatomy pathological diagnosis criteria. The different classification suggested for these tumours and the small amount of cases described in literature makes it hard to know exactly how many of the cases published until now are real. MATERIAL AND METHODS: We present three new cases of PIOC originated from a previous cystic lesion that where treated in our Hospital. Two of them in the posterior jaw region where is more frequent, and the third in the upper jaw. We explain the procedure we used in each case and the aesthetic-functional reconstruction used witches are two fibula osteomyocutaneous free flaps and a bone graft of iliac crest and further placing of implants. The classification, the clinical and radiological diagnosis, the treatment and its survival are discussed. RESULTS: In all three cases we were able to see in the anatomy pathological study an epithelial, exclusively without surrounding oral mucosa affectation or tissues near the lesion as well as the lack of tumorous pathology in other parts of the body. One of the patients died because of premature massive cervical recidiva while the other two patients are currently free form illness, for ten years one of them and fifteen months the other. CONCLUSIONS: The anatomy pathological study of all of the lesions of cystic characteristics at jaw level is very important because of the risk of coexisting with carcinomatous cells. The treatment of these tumours consists in practising aggressive surgery and, in some cases, radio and/or chemotherapy post intervention.  (+info)

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1. (2/3)

BACKGROUND: Squamous odontogenic tumor (SOT) is a rare benign odontogenic epithelial neoplasm. A slow-growing painless expansive swelling is the common presenting symptom. Histopathologically, SOT can be easily misdiagnosed as an acanthomatous ameloblastoma. Although Notch receptors and ligands have been shown to play a role in cell fate decisions in ameloblastomas, the role of these cell signaling molecules in SOT is unknown. CASE REPORT: This paper describes a case of SOT affecting the anterior mandible of a 10-year-old Indian female. The patient was treated by local surgical excision and there has been no follow-up clinical record of recurrence 5 years after primary treatment. Histo?pathological examination revealed a solid, locally-infiltrative neoplasm composed of bland-looking squamatoid islands scattered in a mature fibrous connective tissue stroma and the diagnosis was SOT. Immunohistochemical evaluation showed positive reactivity of varying intensity in the neoplastic epithelial cells for Notch1, Notch3, Notch4, and their ligands Jagged1 and Delta1. Expression patterns showed considerable overlap. No immunoreactivity was detected for Notch2 and Jagged2. CONCLUSIONS: Present findings suggest that Notch receptors and their ligands play differential roles in the cytodifferentiation of SOT.  (+info)

Squamous odontogenic tumor. (3/3)

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Odontogenic tumors are a group of neoplasms that originate from the dental tissues or their remnants, including the odontogenic epithelium, ectomesenchyme, and/or their derivatives. These tumors can be benign or malignant and may affect the jaw bones and surrounding structures. They can cause various symptoms, such as swelling, pain, loosening of teeth, and altered bite. The classification of odontogenic tumors includes a wide range of entities with different biological behaviors, clinical features, and treatment approaches. Accurate diagnosis is essential for proper management and prognosis.

Odontogenic cysts are a type of cyst that originates from the dental tissues or odontogenic apparatus. They are typically found in the jawbones, and can be classified as developmental or inflammatory in origin. Developmental odontogenic cysts arise from remnants of the tooth-forming structures, while inflammatory odontogenic cysts result from an infection or injury to a tooth.

The most common types of odontogenic cysts include:

1. Periapical cyst - an inflammatory cyst that forms at the tip of the root of a dead or non-vital tooth.
2. Dentigerous cyst - a developmental cyst that surrounds the crown of an unerupted or impacted tooth.
3. Follicular cyst - a type of dentigerous cyst that forms around the crown of an unerupted wisdom tooth.
4. Odontogenic keratocyst - a developmental cyst that arises from the dental lamina and has a high recurrence rate.
5. Lateral periodontal cyst - a rare, developmental cyst that forms in the periodontal ligament of a vital tooth.

Odontogenic cysts can cause various symptoms such as swelling, pain, or numbness in the affected area. They may also displace or resorb adjacent teeth. Diagnosis is typically made through radiographic imaging and histopathological examination of tissue samples obtained through biopsy. Treatment options include surgical excision, marsupialization (a procedure that creates an opening between the cyst and oral cavity), or enucleation (removal of the cyst lining).

Ameloblastoma is a slow-growing, non-cancerous tumor that develops in the jawbone, typically in the lower jaw. It originates from the cells that form the enamel (the hard, outer surface of the teeth). This tumor can cause swelling, pain, and displacement or loosening of teeth. In some cases, it may also lead to fractures of the jawbone.

There are different types of ameloblastomas, including solid or multicystic, unicystic, and peripheral ameloblastoma. Treatment usually involves surgical removal of the tumor, with careful monitoring to ensure that it does not recur. In rare cases, more aggressive treatment may be necessary if the tumor is large or has invaded surrounding tissues.

It's important to note that while ameloblastomas are generally benign, they can still cause significant morbidity and should be treated promptly by an oral and maxillofacial surgeon or other qualified healthcare professional.

Jaw neoplasms refer to abnormal growths or tumors in the jawbone (mandible) or maxilla (upper jaw). These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are not considered life-threatening, but they can still cause problems by invading nearby tissues and causing damage. Malignant neoplasms, on the other hand, can spread to other parts of the body and can be life-threatening if not treated promptly and effectively.

Jaw neoplasms can present with various symptoms such as swelling, pain, loose teeth, numbness or tingling in the lips or tongue, difficulty chewing or swallowing, and jaw stiffness or limited movement. The diagnosis of jaw neoplasms typically involves a thorough clinical examination, imaging studies such as X-rays, CT scans, or MRI, and sometimes a biopsy to determine the type and extent of the tumor.

Treatment options for jaw neoplasms depend on several factors, including the type, size, location, and stage of the tumor, as well as the patient's overall health and medical history. Treatment may involve surgery, radiation therapy, chemotherapy, or a combination of these modalities. Regular follow-up care is essential to monitor for recurrence or metastasis (spread) of the neoplasm.

Mandibular neoplasms refer to abnormal growths or tumors that develop in the mandible, which is the lower jawbone. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow-growing and rarely spread to other parts of the body, while malignant neoplasms can invade surrounding tissues and may metastasize (spread) to distant sites.

Mandibular neoplasms can have various causes, including genetic mutations, exposure to certain chemicals or radiation, and infection with certain viruses. The symptoms of mandibular neoplasms may include swelling or pain in the jaw, difficulty chewing or speaking, numbness in the lower lip or chin, loose teeth, and/or a lump or mass in the mouth or neck.

The diagnosis of mandibular neoplasms typically involves a thorough clinical examination, imaging studies such as X-rays, CT scans, or MRI scans, and sometimes a biopsy to confirm the type and extent of the tumor. Treatment options depend on the type, stage, and location of the neoplasm, and may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up care is essential to monitor for recurrence or metastasis.

An Odontogenic Cyst, Calcifying is a specific type of cyst that originates from the dental tissues. It's also known as a calcifying odontogenic cyst or Gorlin cyst. This cyst is characterized by the presence of calcified structures within its lining.

The calcifications can appear as flecks or more complex structures, such as teeth-like formations. The lining of this cyst often contains ghost cells, which are the remains of epithelial cells that have undergone calcification.

These cysts are typically slow-growing and asymptomatic, although they can sometimes cause swelling or pain if they become large enough to compress adjacent tissues. They are most commonly found in the jaw bones, particularly the mandible.

While the exact cause of calcifying odontogenic cysts is not fully understood, they are thought to arise from developmental abnormalities in the tissues that form teeth. Treatment typically involves surgical removal of the cyst.

Maxillary neoplasms refer to abnormal growths or tumors in the maxilla, which is the upper jaw bone. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are slow-growing and do not spread to other parts of the body, while malignant neoplasms can invade surrounding tissues and spread to distant sites.

Maxillary neoplasms can cause various symptoms such as swelling, pain, numbness, loose teeth, or difficulty in chewing or swallowing. They may also cause nasal congestion, nosebleeds, or visual changes if they affect the eye or orbit. The diagnosis of maxillary neoplasms usually involves a combination of clinical examination, imaging studies such as CT or MRI scans, and biopsy to determine the type and extent of the tumor.

Treatment options for maxillary neoplasms depend on several factors, including the type, size, location, and stage of the tumor, as well as the patient's overall health and preferences. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these modalities. Regular follow-up care is essential to monitor for recurrence or metastasis and ensure optimal outcomes.

Odontoma is a type of odontogenic tumor, which means it arises from the tissues that form teeth. It is considered a benign or non-cancerous tumor and is typically slow-growing. Odontomas are usually asymptomatic and are often discovered on routine dental X-rays or during procedures such as wisdom tooth removal.

Odontomas can be classified into two types: complex and compound. Complex odontomas are composed of a haphazard mixture of dental tissue, including enamel, dentin, and cementum, while compound odontomas contain small tooth-like structures called denticles.

These tumors typically occur in the posterior region of the jaw, and while they are usually asymptomatic, some patients may experience symptoms such as swelling, pain, or displacement of teeth. Treatment for odontomas typically involves surgical removal of the tumor.

An odontogenic tumor, squamous type, refers to a specific category of oral tumors that originate from the dental tissues. These tumors are characterized by the abnormal growth of squamous epithelial cells, which are normally found in the outermost layer of the skin and the mucous membranes, including those inside the mouth.

Odontogenic tumors can arise from various components of the dental tissues, such as the odontoblasts, dentin, enamel, cementum, or the epithelial rests of Malassez. The squamous type of odontogenic tumor is typically classified under either one of the following entities:

1. Squamous Odontogenic Tumor (SOT): This is a rare, benign (non-cancerous) neoplasm that primarily affects the tooth-bearing areas of the jaws. SOT is composed of well-differentiated squamous epithelial cells arranged in nests, strands, or sheets, often surrounded by a fibrous stroma. This tumor typically occurs in adults during their third to fifth decades of life and has a slight female predilection.
2. Ameloblastoma with Squamous Metaplasia: Ameloblastoma is a more common odontogenic tumor that usually affects the mandible (lower jaw). In some cases, ameloblastomas may undergo squamous metaplasia, where the original epithelial cells transform into squamous epithelial cells. This variant of ameloblastoma is still considered a benign neoplasm; however, it has a higher recurrence rate compared to conventional ameloblastomas.

It is essential to differentiate these entities from other oral lesions and malignancies through histopathological examination, as the treatment and prognosis may vary depending on the specific diagnosis.

A dentigerous cyst is a type of odontogenic cyst that forms around the crown of an unerupted tooth. It is typically slow-growing and often asymptomatic, but it can cause displacement or resorption of adjacent teeth if it becomes large enough. Dentigerous cysts are more common in permanent teeth than primary teeth, and they are more likely to occur in the mandible (lower jaw) than the maxilla (upper jaw). They are usually diagnosed through radiographic examination and can be treated by surgical removal of the cyst along with the affected tooth. If left untreated, dentigerous cysts can continue to grow and may eventually develop into a tumor or cancer.

A radicular cyst is a type of dental cyst that forms around the root of a tooth, usually as a result of chronic infection or inflammation. It is also known as a periapical cyst. The cyst develops from the accumulation of fluid and cells in the periodontal ligament, which is the tissue that connects the tooth to the jawbone.

Radicular cysts are often caused by untreated dental caries or trauma to the tooth that allows bacteria to enter the pulp chamber of the tooth and cause an infection. Over time, the infection can spread to the surrounding tissues, leading to the formation of a cyst. Symptoms of a radicular cyst may include pain, swelling, and tenderness in the affected area. Treatment typically involves removing the affected tooth and the cyst through a surgical procedure.

Gingival neoplasms refer to abnormal growths or tumors that occur in the gingiva, which are the part of the gums that surround the teeth. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms include conditions such as fibromas, papillomas, and hemangiomas, while malignant neoplasms are typically squamous cell carcinomas.

Gingival neoplasms can present with a variety of symptoms, including swelling, bleeding, pain, and loose teeth. They may also cause difficulty with chewing, speaking, or swallowing. The exact cause of these neoplasms is not always known, but risk factors include tobacco use, alcohol consumption, poor oral hygiene, and certain viral infections.

Diagnosis of gingival neoplasms typically involves a thorough clinical examination, including a dental exam and biopsy. Treatment options depend on the type and stage of the neoplasm, but may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular dental check-ups and good oral hygiene practices can help to detect gingival neoplasms at an early stage and improve treatment outcomes.

Jaw diseases refer to a variety of conditions that affect the temporomandibular joint (TMJ) and the surrounding muscles, as well as dental disorders that can impact the jaw. Some common examples include:

1. Temporomandibular Joint Disorders (TMD): These are problems with the TMJ and the muscles that control jaw movement. Symptoms may include pain, clicking or popping sounds, and limited movement of the jaw.

2. Osteonecrosis of the Jaw: This is a condition where bone in the jaw dies due to lack of blood supply. It can be caused by radiation therapy, chemotherapy, or certain medications.

3. Dental Cavities: These are holes in the teeth caused by bacteria. If left untreated, they can cause pain, infection, and damage to the jawbone.

4. Periodontal Disease: This is an infection of the gums and bones that support the teeth. Advanced periodontal disease can lead to loss of teeth and damage to the jawbone.

5. Jaw Fractures: These are breaks in the jawbone, often caused by trauma.

6. Oral Cancer: This is a type of cancer that starts in the mouth or throat. If not treated early, it can spread to the jaw and other parts of the body.

7. Cysts and Tumors: These are abnormal growths in the jawbone or surrounding tissues. While some are benign (non-cancerous), others can be malignant (cancerous).

8. Osteomyelitis: This is an infection of the bone, often occurring in the lower jaw. It can cause pain, swelling, and fever.

9. Oral Thrush: This is a fungal infection that causes white patches on the inside of the mouth. If left untreated, it can spread to the jaw and other parts of the body.

10. Sinusitis: Inflammation of the sinuses can sometimes cause pain in the upper jaw.

Maxillary diseases refer to conditions that affect the maxilla, which is the upper bone of the jaw. This bone plays an essential role in functions such as biting, chewing, and speaking, and also forms the upper part of the oral cavity, houses the upper teeth, and supports the nose and the eyes.

Maxillary diseases can be caused by various factors, including infections, trauma, tumors, congenital abnormalities, or systemic conditions. Some common maxillary diseases include:

1. Maxillary sinusitis: Inflammation of the maxillary sinuses, which are air-filled cavities located within the maxilla, can cause symptoms such as nasal congestion, facial pain, and headaches.
2. Periodontal disease: Infection and inflammation of the tissues surrounding the teeth, including the gums and the alveolar bone (which is part of the maxilla), can lead to tooth loss and other complications.
3. Maxillary fractures: Trauma to the face can result in fractures of the maxilla, which can cause pain, swelling, and difficulty breathing or speaking.
4. Maxillary cysts and tumors: Abnormal growths in the maxilla can be benign or malignant and may require surgical intervention.
5. Oral cancer: Cancerous lesions in the oral cavity, including the maxilla, can cause pain, swelling, and difficulty swallowing or speaking.

Treatment for maxillary diseases depends on the specific condition and its severity. Treatment options may include antibiotics, surgery, radiation therapy, or chemotherapy. Regular dental check-ups and good oral hygiene practices can help prevent many maxillary diseases.

Panoramic radiography is a specialized type of dental X-ray imaging that captures a panoramic view of the entire mouth, including the teeth, upper and lower jaws, and surrounding structures. It uses a special machine that rotates around the head, capturing images as it moves. This technique provides a two-dimensional image that is helpful in diagnosing and planning treatment for various dental conditions such as impacted teeth, bone abnormalities, and jaw disorders.

The panoramic radiograph can also be used to assess the development and positioning of wisdom teeth, detect cysts or tumors in the jaws, and evaluate the effects of trauma or injury to the mouth. It is a valuable tool for dental professionals as it allows them to see a comprehensive view of the oral structures, which may not be visible with traditional X-ray techniques.

It's important to note that while panoramic radiography provides valuable information, it should be used in conjunction with other diagnostic tools and clinical examinations to ensure accurate diagnosis and treatment planning.

An impacted tooth is a condition where a tooth fails to erupt into the oral cavity within its expected time frame, resulting in its partial or complete entrapment within the jawbone or soft tissues. This commonly occurs with wisdom teeth (third molars) but can affect any tooth. Impacted teeth may cause problems such as infection, decay of adjacent teeth, gum disease, or cyst formation, and they may require surgical removal.

A Follicular Cyst is a type of cyst that forms within a follicle, which is the sac-like structure in the skin that contains and protects a hair root. In particular, it refers to a specific condition in the ovary where a follicle fails to rupture or release an egg after maturation, instead continuing to grow and fill with fluid, forming a cyst. These cysts are usually asymptomatic but can become large and cause symptoms such as pelvic pain or discomfort, irregular menstrual cycles, or abnormal vaginal bleeding. In most cases, follicular cysts resolve on their own within 2-3 menstrual cycles, but in rare cases, they may require medical intervention if they become complicated or do not resolve.

A fibroma is a benign (non-cancerous) tumor that consists primarily of fibrous or connective tissue. It can occur in various parts of the body, including the skin, mouth, and internal organs. The term "fibroma" is often used to describe any benign fibrous growth, but there are specific types of fibromas such as dermatofibroma (found in the skin), oral fibroma (found in the mouth), and benign fibrous histiocytoma (found in soft tissues).

It's important to note that while fibromas are generally harmless, they can cause discomfort or problems depending on their size and location. If a fibroma is causing issues or there's concern about its growth or malignancy, it should be evaluated by a healthcare professional for potential removal or further assessment.

An adenomatoid tumor is a benign (non-cancerous) neoplasm that typically arises in the serosal surfaces of the reproductive organs, such as the epididymis in men and the fallopian tube or uterus in women. These tumors are composed of epithelioid cells arranged in tubules, glands, or cysts, and they can sometimes be mistaken for malignant tumors due to their gross appearance. However, adenomatoid tumors are generally slow-growing and do not spread to other parts of the body. They are usually treated with surgical excision and have an excellent prognosis.

A myxoma is a type of benign (non-cancerous) tumor that develops in the heart, specifically in the heart's chambers or valves. It is the most common primary cardiac tumor in adults and typically affects the left atrium. Myxomas are composed of gelatinous, mucoid material and may have a stalk-like attachment to the endocardium (the inner lining of the heart).

Myxomas can vary in size and may cause symptoms such as shortness of breath, fatigue, chest pain, coughing, and fever. These symptoms are due to obstruction of blood flow within the heart or embolization (detachment and travel) of tumor fragments to other parts of the body. Surgical removal is usually required to treat myxomas, as they can lead to serious complications if left untreated.

Odontogenesis is the process of tooth development that involves the formation and calcification of teeth. It is a complex process that requires the interaction of several types of cells, including epithelial cells, mesenchymal cells, and odontoblasts. The process begins during embryonic development with the formation of dental lamina, which gives rise to the tooth bud. As the tooth bud grows and differentiates, it forms the various structures of the tooth, including the enamel, dentin, cementum, and pulp. Odontogenesis is completed when the tooth erupts into the oral cavity. Abnormalities in odontogenesis can result in developmental dental anomalies such as tooth agenesis, microdontia, or odontomas.

A focal infection is a focus or source of infection that can spread and cause harm to other parts of the body. A "focal infection, dental" refers to an infection that originates in the teeth or surrounding tissues of the mouth and then spreads to other parts of the body. This can occur when bacteria or other pathogens from a dental infection enter the bloodstream and travel to distant sites, where they can cause inflammation, tissue damage, and illness.

Dental focal infections can be caused by various conditions, such as tooth decay, periodontal disease, abscesses, or other oral infections. The bacteria involved in dental infections are often part of the normal oral flora but can become pathogenic under certain circumstances, such as when they gain access to deeper tissues or the bloodstream due to trauma, surgery, or poor oral hygiene.

If left untreated, dental focal infections can lead to serious health complications, including heart disease, brain abscesses, and other systemic infections. It is essential to maintain good oral hygiene and seek professional dental care to prevent and treat dental infections, reducing the risk of developing focal infections and related health issues.

Basal Cell Nevus Syndrome (BCNS), also known as Gorlin-Goltz Syndrome, is a rare genetic disorder that is characterized by the development of multiple basal cell carcinomas (BCCs), which are skin cancer tumors that arise from the basal cells in the outermost layer of the skin.

The syndrome is caused by mutations in the PTCH1 gene, which regulates the hedgehog signaling pathway involved in embryonic development and tissue growth regulation. The condition is inherited in an autosomal dominant manner, meaning that a child has a 50% chance of inheriting the mutated gene from an affected parent.

Individuals with BCNS typically develop hundreds to thousands of BCCs over their lifetime, often beginning in childhood or adolescence. They may also have other benign and malignant tumors, such as medulloblastomas (brain tumors), fibromas, and rhabdomyosarcomas.

Additional features of BCNS can include:

1. Facial abnormalities, such as a broad nasal bridge, widely spaced eyes, and pits or depressions on the palms and soles.
2. Skeletal abnormalities, such as spine deformities, rib anomalies, and jaw cysts.
3. Developmental delays and intellectual disabilities in some cases.
4. Increased risk of other cancers, including breast, ovarian, and lung cancer.

Early detection and management of BCCs and other tumors are crucial for individuals with BCNS to prevent complications and improve their quality of life. Regular dermatological examinations, sun protection measures, and surgical removal of tumors are common treatment approaches.

Mandibular diseases refer to conditions that affect the mandible, or lower jawbone. These diseases can be classified as congenital (present at birth) or acquired (developing after birth). They can also be categorized based on the tissues involved, such as bone, muscle, or cartilage. Some examples of mandibular diseases include:

1. Mandibular fractures: These are breaks in the lower jawbone that can result from trauma or injury.
2. Osteomyelitis: This is an infection of the bone and surrounding tissues, which can affect the mandible.
3. Temporomandibular joint (TMJ) disorders: These are conditions that affect the joint that connects the jawbone to the skull, causing pain and limited movement.
4. Mandibular tumors: These are abnormal growths that can be benign or malignant, and can develop in any of the tissues of the mandible.
5. Osteonecrosis: This is a condition where the bone tissue dies due to lack of blood supply, which can affect the mandible.
6. Cleft lip and palate: This is a congenital deformity that affects the development of the face and mouth, including the lower jawbone.
7. Mandibular hypoplasia: This is a condition where the lower jawbone does not develop properly, leading to a small or recessed chin.
8. Developmental disorders: These are conditions that affect the growth and development of the mandible, such as condylar hyperplasia or hemifacial microsomia.

A fibroma, ossifying is a benign (non-cancerous) tumor that typically develops in the periodontal ligament, which is the tissue that connects the tooth to the jawbone. This type of fibroma is characterized by the formation of bone-like tissue within the tumor. It usually appears as a firm, slow-growing nodule or mass that can cause pain or discomfort, particularly when biting down on the affected tooth.

The exact cause of ossifying fibromas is not well understood, but they are thought to arise from an overgrowth of cells in the periodontal ligament. They are more common in women than men and typically occur in people between the ages of 20 and 40. Treatment usually involves surgical removal of the tumor, along with any affected tissue or teeth. In some cases, recurrence may occur, so regular follow-up appointments with a dental professional are recommended.

A periodontal cyst, also known as a radicular cyst or dental cyst, is a type of odontogenic cyst that forms from the tissue of the periodontium, which surrounds and supports the teeth. It typically develops at the apex (tip) of a dead or non-vital tooth root and is filled with fluid. The cyst can grow slowly and painlessly, often going unnoticed until it becomes quite large or causes symptoms such as swelling, tenderness, or tooth mobility.

Periodontal cysts are usually asymptomatic and are often discovered during routine dental x-rays. If left untreated, they can eventually lead to the destruction of surrounding bone and tissue, potentially causing teeth to become loose or even fall out. Treatment typically involves surgical removal of the cyst along with the affected tooth, followed by careful monitoring to ensure that the cyst does not recur.

Cyst fluid refers to the fluid accumulated within a cyst, which is a closed sac-like or capsular structure, typically filled with liquid or semi-solid material. Cysts can develop in various parts of the body for different reasons, and the composition of cyst fluid may vary depending on the type of cyst and its location.

In some cases, cyst fluid might contain proteins, sugars, hormones, or even cells from the surrounding tissue. Infected cysts may have pus-like fluid, while cancerous or precancerous cysts might contain abnormal cells or tumor markers. The analysis of cyst fluid can help medical professionals diagnose and manage various medical conditions, including infections, inflammatory diseases, genetic disorders, and cancers.

It is important to note that the term 'cyst fluid' generally refers to the liquid content within a cyst, but the specific composition and appearance of this fluid may vary significantly depending on the underlying cause and type of cyst.

A periodontal abscess is a localized collection of pus in the tissues surrounding and supporting the teeth, caused by an infection. It's typically characterized by symptoms such as pain, swelling, redness, and sometimes drainage of pus from the affected area. The infection usually arises from dental plaque that accumulates on the teeth and gums, leading to periodontal disease. If left untreated, a periodontal abscess can result in tissue destruction, bone loss, and even tooth loss. Treatment typically involves draining the abscess, removing any infected tissue, and providing oral hygiene instruction to prevent future infections. In some cases, antibiotics may also be prescribed to help clear up the infection.

Mandibular prosthesis implantation is a dental surgical procedure that involves the placement of dental implants into the mandible (lower jawbone) to support and retain a prosthetic restoration, such as a denture or fixed bridge. This procedure is typically performed to restore oral function, aesthetics, and quality of life for patients who have lost all or most of their natural lower teeth due to injury, decay, or other reasons.

The implantation process typically involves several steps. First, the dental surgeon will carefully evaluate the patient's jawbone density and overall oral health to determine if they are a good candidate for the procedure. If so, the surgeon will then place one or more titanium implants into the mandible, using specialized surgical techniques to ensure proper placement and alignment.

After the implant(s) have been placed, the patient will typically undergo a healing period of several months, during which time the jawbone will gradually fuse with the implant(s) in a process called osseointegration. Once this process is complete, the surgeon will attach an abutment to each implant, which will serve as a connector between the implant and the prosthetic restoration.

Finally, the dental prosthesis (such as a denture or bridge) will be fabricated and attached to the abutments, providing a stable and secure replacement for the missing teeth. With proper care and maintenance, mandibular prosthesis implantation can provide a long-lasting and effective solution for patients with significant tooth loss.

Maxillary sinus neoplasms refer to abnormal growths or tumors that develop in the maxillary sinuses, which are located in the upper part of your cheekbones, below your eyes. These growths can be benign (non-cancerous) or malignant (cancerous).

Benign neoplasms may include conditions such as an osteoma (a benign bone tumor), a papilloma (a benign growth of the lining of the sinus), or a fibrous dysplasia (a condition where bone is replaced by fibrous tissue).

Malignant neoplasms, on the other hand, can be primary (originating in the maxillary sinuses) or secondary (spreading to the maxillary sinuses from another site in the body). Common types of malignant tumors that arise in the maxillary sinus include squamous cell carcinoma, adenocarcinoma, and mucoepidermoid carcinoma.

Symptoms of maxillary sinus neoplasms may include nasal congestion, nosebleeds, facial pain or numbness, vision changes, and difficulty swallowing or speaking. Treatment options depend on the type, size, and location of the tumor but may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

A third molar is the most posterior of the three molars present in an adult human dental arch. They are also commonly known as wisdom teeth, due to their late eruption period which usually occurs between the ages of 17-25, a time traditionally associated with gaining maturity and wisdom.

Anatomically, third molars have four cusps, making them the largest of all the teeth. However, not everyone develops third molars; some people may have one, two, three or no third molars at all. In many cases, third molars do not have enough space to fully erupt and align properly with the rest of the teeth, leading to impaction, infection, or other dental health issues. As a result, third molars are often extracted if they cause problems or if there is a risk they will cause problems in the future.

Dental enamel is the hard, outermost layer of a tooth that protects the dentin and pulp inside. It is primarily made up of minerals, mainly hydroxyapatite, and contains very little organic material. However, during the formation of dental enamel, proteins are synthesized and secreted by ameloblast cells, which help in the development and mineralization of the enamel. These proteins play a crucial role in the proper formation and structure of the enamel.

Some of the main dental enamel proteins include:

1. Amelogenin: This is the most abundant protein found in developing enamel, accounting for about 90% of the organic matrix. Amelogenin helps regulate the growth and organization of hydroxyapatite crystals during mineralization. It also plays a role in determining the final hardness and structure of the enamel.

2. Enamelin: This protein is the second most abundant protein in developing enamel, accounting for about 5-10% of the organic matrix. Enamelin is involved in the elongation and thickening of hydroxyapatite crystals during mineralization. It also helps maintain the stability of the enamel structure.

3. Ameloblastin: This protein is produced by ameloblast cells and is essential for proper enamel formation. Ameloblastin plays a role in regulating crystal growth, promoting adhesion between crystals, and maintaining the structural integrity of the enamel.

4. Tuftelin: This protein is found in both dentin and enamel but is more abundant in enamel. Tuftelin is involved in the initiation of mineralization and helps regulate crystal growth during this process.

5. Dentin sialophosphoprotein (DSPP): Although primarily associated with dentin formation, DSPP is also found in developing enamel. It plays a role in regulating crystal growth and promoting adhesion between crystals during mineralization.

After the formation of dental enamel is complete, these proteins are largely degraded and removed, leaving behind the highly mineralized and hard tissue that characterizes mature enamel. However, traces of these proteins may still be present in the enamel and could potentially play a role in its structure and properties.

Photomicrography is not a medical term per se, but it is a technique often used in the field of medicine and pathology. It refers to the process of taking photographs through a microscope, using specialized equipment and techniques to capture detailed images of specimens or structures that are too small to be seen by the naked eye. These images can be used for various purposes, such as medical research, diagnosis, education, and publication.

In summary, photomicrography is the photography of microscopic subjects, which can have many applications in the medical field.

Tumor markers are substances that can be found in the body and their presence can indicate the presence of certain types of cancer or other conditions. Biological tumor markers refer to those substances that are produced by cancer cells or by other cells in response to cancer or certain benign (non-cancerous) conditions. These markers can be found in various bodily fluids such as blood, urine, or tissue samples.

Examples of biological tumor markers include:

1. Proteins: Some tumor markers are proteins that are produced by cancer cells or by other cells in response to the presence of cancer. For example, prostate-specific antigen (PSA) is a protein produced by normal prostate cells and in higher amounts by prostate cancer cells.
2. Genetic material: Tumor markers can also include genetic material such as DNA, RNA, or microRNA that are shed by cancer cells into bodily fluids. For example, circulating tumor DNA (ctDNA) is genetic material from cancer cells that can be found in the bloodstream.
3. Metabolites: Tumor markers can also include metabolic products produced by cancer cells or by other cells in response to cancer. For example, lactate dehydrogenase (LDH) is an enzyme that is released into the bloodstream when cancer cells break down glucose for energy.

It's important to note that tumor markers are not specific to cancer and can be elevated in non-cancerous conditions as well. Therefore, they should not be used alone to diagnose cancer but rather as a tool in conjunction with other diagnostic tests and clinical evaluations.

The mandible, also known as the lower jaw, is the largest and strongest bone in the human face. It forms the lower portion of the oral cavity and plays a crucial role in various functions such as mastication (chewing), speaking, and swallowing. The mandible is a U-shaped bone that consists of a horizontal part called the body and two vertical parts called rami.

The mandible articulates with the skull at the temporomandibular joints (TMJs) located in front of each ear, allowing for movements like opening and closing the mouth, protrusion, retraction, and side-to-side movement. The mandible contains the lower teeth sockets called alveolar processes, which hold the lower teeth in place.

In medical terminology, the term "mandible" refers specifically to this bone and its associated structures.

Root resorption is a process that occurs when the body's own cells, called odontoclasts, break down and destroy the hard tissue of the tooth root. This can occur as a result of various factors such as trauma, infection, or orthodontic treatment. In some cases, it may be a normal part of the tooth development and eruption process in children. However, excessive or pathological root resorption can lead to weakening and loss of the tooth. It is often asymptomatic and discovered during routine dental x-rays.

Multiple primary neoplasms refer to the occurrence of more than one primary malignant tumor in an individual, where each tumor is unrelated to the other and originates from separate cells or organs. This differs from metastatic cancer, where a single malignancy spreads to multiple sites in the body. Multiple primary neoplasms can be synchronous (occurring at the same time) or metachronous (occurring at different times). The risk of developing multiple primary neoplasms increases with age and is associated with certain genetic predispositions, environmental factors, and lifestyle choices such as smoking and alcohol consumption.

Keratins are a type of fibrous structural proteins that constitute the main component of the integumentary system, which includes the hair, nails, and skin of vertebrates. They are also found in other tissues such as horns, hooves, feathers, and reptilian scales. Keratins are insoluble proteins that provide strength, rigidity, and protection to these structures.

Keratins are classified into two types: soft keratins (Type I) and hard keratins (Type II). Soft keratins are found in the skin and simple epithelial tissues, while hard keratins are present in structures like hair, nails, horns, and hooves.

Keratin proteins have a complex structure consisting of several domains, including an alpha-helical domain, beta-pleated sheet domain, and a non-repetitive domain. These domains provide keratin with its unique properties, such as resistance to heat, chemicals, and mechanical stress.

In summary, keratins are fibrous structural proteins that play a crucial role in providing strength, rigidity, and protection to various tissues in the body.

Retrospective studies, also known as retrospective research or looking back studies, are a type of observational study that examines data from the past to draw conclusions about possible causal relationships between risk factors and outcomes. In these studies, researchers analyze existing records, medical charts, or previously collected data to test a hypothesis or answer a specific research question.

Retrospective studies can be useful for generating hypotheses and identifying trends, but they have limitations compared to prospective studies, which follow participants forward in time from exposure to outcome. Retrospective studies are subject to biases such as recall bias, selection bias, and information bias, which can affect the validity of the results. Therefore, retrospective studies should be interpreted with caution and used primarily to generate hypotheses for further testing in prospective studies.

A Biological Specimen Bank, also known as a biobank or tissue bank, is a type of medical facility that collects, stores, and distributes biological samples for research purposes. These samples can include tissues, cells, DNA, blood, and other bodily fluids, and are often collected during medical procedures or from donors who have given their informed consent. The samples are then cataloged and stored in specialized conditions to preserve their quality and integrity.

Biobanks play a critical role in advancing medical research by providing researchers with access to large numbers of well-characterized biological samples. This allows them to study the underlying causes of diseases, develop new diagnostic tests and treatments, and evaluate the safety and effectiveness of drugs and other therapies. Biobanks may be established for specific research projects or as part of larger, more comprehensive efforts to build biomedical research infrastructure.

It is important to note that the use of biological specimens in research is subject to strict ethical guidelines and regulations, which are designed to protect the privacy and interests of donors and ensure that the samples are used responsibly and for legitimate scientific purposes.

Immunohistochemistry (IHC) is a technique used in pathology and laboratory medicine to identify specific proteins or antigens in tissue sections. It combines the principles of immunology and histology to detect the presence and location of these target molecules within cells and tissues. This technique utilizes antibodies that are specific to the protein or antigen of interest, which are then tagged with a detection system such as a chromogen or fluorophore. The stained tissue sections can be examined under a microscope, allowing for the visualization and analysis of the distribution and expression patterns of the target molecule in the context of the tissue architecture. Immunohistochemistry is widely used in diagnostic pathology to help identify various diseases, including cancer, infectious diseases, and immune-mediated disorders.

The Ki-67 antigen is a cellular protein that is expressed in all active phases of the cell cycle (G1, S, G2, and M), but not in the resting phase (G0). It is often used as a marker for cell proliferation and can be found in high concentrations in rapidly dividing cells. Immunohistochemical staining for Ki-67 can help to determine the growth fraction of a group of cells, which can be useful in the diagnosis and prognosis of various malignancies, including cancer. The level of Ki-67 expression is often associated with the aggressiveness of the tumor and its response to treatment.

Squamous odontogenic tumors (SOTs) are very rare benign locally infiltrative odontogenic neoplasms of epithelial origin. Only ... Squamous Odontogenic Tumor: Literature Review Focusing on the Radiographic Features and Differential Diagnosis. Open Dent J. ... Badni M, Nagaraja A, Kamath V. Squamous odontogenic tumor: A case report and review of literature. J Oral Maxillofac Pathol. ... This presentation is similar to that of squamous cell carcinomas; however, the epithelium of SOT is highly differentiated. ...
Squamous odontogenic tumor • Stafne defect • Stan Brown • Stanley D. Tylman • Stanley McInnis • Stannous fluoride • Stellate ... Calcifying epithelial odontogenic tumor • Calcifying odontogenic cyst • Calcium hydroxide • Calculus • California Dental ... Odontogenic keratocyst • Odontogenic myxoma • Odontogenic cyst • Odontoma • Ohaguro • Ohio College of Dental Surgery • Ohio ... Adenomatoid odontogenic tumor • Adhesive Dentistry • Aetna • Agar • Aggregatibacter actinomycetemcomitans • Aim toothpaste • ...
"Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour". Journal. 74 (2): 165-165h ... Malignant transformation to squamous cell carcinoma may occur, but is unusual. Recurrence is likely when treated by simple ... Radiologically Odontogenic myxoma Ameloblastoma Central giant-cell granuloma Adenomatoid odontogenic tumor Dentigerous cyst ( ... On a CT scan, the radiodensity of a keratocystic odontogenic tumour is about 30 Hounsfield units, which is about the same as ...
Very rarely, a brain tumor might cause toothache.: 80, 81 Another chronic facial pain syndrome which can mimic toothache is ... Severe trismus may occur in when the muscles of mastication are involved in an odontogenic infection, making any surgical ... Examples include neoplasms of the gingival or alveolar mucosa (usually squamous cell carcinoma),: 299 conditions which cause ... Toothache may be caused by dental (odontogenic) conditions (such as those involving the dentin-pulp complex or periodontium), ...
... odontogenic tumor Cementoblastoma Cementoma Odontogenic keratocyst Odontogenic carcinoma Odontogenic myxoma Odontoma Squamous ... Adenomatoid odontogenic tumor Ameloblastic fibroma Ameloblastic fibro-odontoma Ameloblastoma, a type of odontogenic tumor ... An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes. Examples include: ... odontogenic tumour v t e (Articles with short description, Short description matches Wikidata, Short description is different ...
... thus renamed as Keratocystic odontogenic tumor and Calcifying odontogenic tumor, respectively. Cystic ameloblastoma Long ... or the malignant squamous cell carcinoma and mucoepidermoid carcinoma. On histopathology, cholesterol clefts indicate mainly a ... Botryoid odontogenic cyst viii. Glandular odontogenic cyst ix. Calcifying odontogenic cyst (b) Non-odontogenic i. Midpalatal ... "Odontogenic cysts and tumors". UTMB Department of otolaryngology. Archived from the original on 23 August 2012. Retrieved 11 ...
... which is also characterized by keratocystic odontogenic tumors of the jaw, palmar or plantar (sole of the foot) pits, ... Basal Cell and Squamous Cell Skin Cancers (PDF). NCCN Clinical Practice Guidelines in Oncology. National Comprehensive Cancer ... Cure rate can be as high as 95% for small tumor, or as low as 80% for large tumors. A variation of an external brachytherapy is ... This tumor accounts for approximately 70% of non-melanoma skin cancers. In 80 percent of all cases, basal-cell carcinoma ...
... ocular surface squamous neoplasia (OSSN), or amelanotic melanoma. Atrial myxoma Cutaneous myxoma Odontogenic myxoma Myxomas are ... Myxoid tumor Cutaneous myxoma Carney complex Myxomatosis Primary tumors of the heart Myxomatous degeneration "Myxoma" at ... benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors. Conjunctival myxomas are ... It is most commonly found in the heart (and is the most common primary tumor of the heart in adults) but can also occur in ...
... the most common type of odontogenic tumor), are characterized by activating CTNNB1 mutations. Papillary craniopharyngiomas are ... On light microscopy, the cysts are seen to be lined by stratified squamous epithelium. Keratin pearls may also be seen. The ... Large pituitary tumors can paradoxically elevate blood prolactin levels due to the "stalk effect". This elevation occurs as a ... The tumor, being in the pituitary gland, can cause secondary health problems. The immune system, thyroid levels, growth hormone ...
... odontogenic cyst, calcifying MeSH C04.557.695.607 - odontogenic tumor, squamous MeSH C04.557.695.610 - odontoma MeSH C04.588. ... sertoli-leydig cell tumor MeSH C04.557.475.750.847.249 - leydig cell tumor MeSH C04.557.475.750.847.500 - sertoli cell tumor ... mixed tumor, malignant MeSH C04.557.435.530 - mixed tumor, mesodermal MeSH C04.557.435.540 - mixed tumor, mullerian MeSH ... giant cell tumors MeSH C04.557.450.565.380.380 - giant cell tumor of bone MeSH C04.557.450.565.465 - mastocytosis MeSH C04.557. ...
Squamous cell carcinoma - fast-growing tumor that is often ulcerated. It spreads slowly and invades bone tissue. It is the most ... Peripheral odontogenic fibroma - grows from the periodontal ligament. It contains no invasion of bone tissue and has a firm, ... Melanoma - cancerous tumor that spreads to regional lymph nodes and lungs. Bone destruction is usually evident around the tumor ... It is the most common benign tumor in dogs. Peripheral acanthomatous ameloblastoma - a slow-growing tumor that has a raised, ...
It is also known as a calcifying cystic odontogenic tumor, which is a proliferation of odontogenic epithelium and scattered ... In general, the epithelium seen is of stratified squamous type and is 5-8 cells thick. Additionally, focal areas of stellate ... There are small number of malignant odontogenic ghost cell tumors (odontogenic ghost cell carcinoma). These are aggressive and ... the diagnosis was considered to be a calcifying odontogenic cyst or calcifying odontogenic tumor. It was treated with an ...
Botryoid odontogenic cyst (BOC) was once classified as one type of LPC by Altini and Shear in 1992. It was opposed by Van der ... Squamous cell carcinoma development has been reported within literature to occur in lateral periodontal cysts. Lateral ... Sciubba, J.J. (2001). Tumors and cysts of the jaws. Washington, DC: Armed Forces Institute of Pathology. ISBN 1-881041-62-X. ... Baker RD, D'Onofrio ED, Corio RL, Crawford BE, Terry BC (June 1979). "Squamous-cell carcinoma arising in a lateral periodontal ...
... a tissue-specific member of the small proline-rich protein family that is not expressed in esophageal tumors". Cell Growth & ... "Small proline-rich proteins are cross-bridging proteins in the cornified cell envelopes of stratified squamous epithelia". ... expression of protease inhibitor and small proline-rich protein genes between normal human oral tissue and odontogenic ...
Most primordial cysts have proven to be Keratocystic odontogenic tumors Orthokeratinized odontogenic cyst; a variant of the ... Rarely, the walls of this type of cyst can progress into mucoepidermoid carcinoma, ameloblastoma or squamous carcinoma if the ... Other cysts of the jaws are termed non-odontogenic cysts. Non-odontogenic cysts form from tissues other than those involved in ... Keratocystic odontogenic tumor Gingival cyst of the newborn; an inclusion cyst from remnants of the dental lamina on a newborn ...
Neoplasms, such as metastatic squamous cell carcinoma to the submandibular lymph nodes or a salivary gland tumour, could create ... The radiolucent defect here may be superimposed on the lower anterior teeth and be mistaken for an odontogenic lesion. ... Very rarely, since the defect contains salivary gland tissue, salivary gland tumors can occur within an established defect but ...
Pindborg tumor A rare odontogenic tumor that is radiolucent with well-defined border and associated calcified radiopaque foci. ... In addition, a squamous cell carcinoma may rarely arise in the lining of a dentigerous cyst. Transformation from normal ... Adenomatoid odontogenic tumor Also shows similar features as dentigerous cyst; however, the differentiation is by the presence ... Unicystic ameloblastoma The most common radiolucent, benign odontogenic tumor, which may be unilocular or multilocular. It may ...
0 Squamous odontogenic tumor M9320/0 Odontogenic myxoma Odontogenic myxofibroma M9321/0 Central odontogenic fibroma Odontogenic ... M9340/0 Calcifying epithelial odontogenic tumor Pindbord tumor M9341/1 clear cell odontogenic tumor M9342/3 Odontogenic ... benign M9270/1 Odontogenic tumor, NOS M9270/3 Odontogenic tumor, malignant Odontogenic carcinoma/sarcoma Primary intraosseous ... Adenomatoid odontogenic tumor Adenomeloblastoma M9301/0 Calcifying odontogenic cyst M9302/0 Odontogenic ghost cell tumor M9310/ ...
Hepatic tumors and squamous cell carcinomas of the esophagus, oropharynx and uvula are solid tumors commonly linked to FA. ... Odontogenic keratocysts are found in approximately 75% of individuals with the disease and often occur early in life. The most ... Other tumors increased in frequency include; osteomas, adrenal adenomas and carcinomas, thyroid tumors and desmoid tumors. The ... but also the development of multiple independent primary tumors. Many of these syndromes are caused by mutations in tumor ...
... tumor-like, exuberant tissue response to localized irritation or trauma Chronic granulomatous disorders Orofacial ... lesions tend to be nodular and may ulcerate Papillomas are usually comparative to a wart-like appearance Ulceration Squamous ... to gingival enlargement or salivary gland swelling which may result in xerostomia Developmental Unerupted teeth Odontogenic ... HPV Fibro-osseous Cherubism Fibrous dysplasia Paget's disease Neoplasms Carcinoma Leukeamia Lymphoma Myeloma Odontogenic ...
Increased nuclear β-catenin levels have also been noted in basal cell carcinoma (BCC), head and neck squamous cell carcinoma ( ... Minde DP, Anvarian Z, Rüdiger SG, Maurice MM (August 2011). "Messing up disorder: how do missense mutations in the tumor ... Pilomatricoma, craniopharyngioma, and calcifying odontogenic cyst". American Journal of Clinical Pathology. 120 (5): 732-736. ... Hassanein AM, Glanz SM, Kessler HP, Eskin TA, Liu C (November 2003). "beta-Catenin is expressed aberrantly in tumors expressing ...
Squamous odontogenic tumors (SOTs) are very rare benign locally infiltrative odontogenic neoplasms of epithelial origin. Only ... Squamous Odontogenic Tumor: Literature Review Focusing on the Radiographic Features and Differential Diagnosis. Open Dent J. ... Badni M, Nagaraja A, Kamath V. Squamous odontogenic tumor: A case report and review of literature. J Oral Maxillofac Pathol. ... This presentation is similar to that of squamous cell carcinomas; however, the epithelium of SOT is highly differentiated. ...
Squamous odontogenic tumor and squamous odontogenic tumor-like proliferations in odontogenic cysts: an updated analysis of 170 ... Squamous odontogenic tumors arising in odontogenic cysts. J Oral Med. 1981;36(2):35-8. PMid:6942129.. 8 Simon JH, Jensen JL. ... In rare cases, squamous odontogenic tumor-like proliferation (SOT-LP) can be observed arising from odontogenic cysts (SOT-LPOC ... Squamous odontogenic tumor-like proliferations (SOT-LP) versus intraosseous squamous cell carcinoma in residual cyst. J Oral ...
... of odontogenic tumors). Oral malignant melanoma, oral squamous cell carcinoma, and T3 tumors had the highest prevalence of ... Bone lysis was present in 74.4% of tumors. Oral squamous cell carcinoma, sarcomas, and T2-T3 (, 2 cm) tumors had a ... Thoracic metastasis was diagnosed in 4.9% (0.9% odontogenic, 6.5% nonodontogenic) of oral tumors. Oral malignant melanoma and ... Abdominal metastasis was diagnosed in 2% of oral tumors (0% odontogenic, 3.1% nonodontogenic) and cytologically confirmed in 2 ...
Acanthomatous ameloblastoma (AA) also presents histological features very similar to those of the squamous odontogenic tumor ... Ameloblastoma belongs to the benign epithelial odontogenic tumor subgroup, and it is probably one of the most controversial and ... The current WHO classification of odontogenic tumors [11] finally reports that the hystological type does not condition the ... Histological sections showed tumor cells at a distance of 8 mm from the clinical and radiographic limit of the lesion, so the ...
Epithelial tumors of penis - squamous adenocarcinoma cell carcinoma with variants of penis (closed to accrual) 18. Squamous ... Odontogenic malignant tumors 22. Pancreatic neuroendocrine tumor (PNET) (formerly named: Endocrine carcinoma of pancreas and ... Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03 ... Cell tumor of the testes and extragonadal germ tumors: A) Seminoma and testicular sex cord cancer B) Non seminomatous tumor C) ...
... chapters in different books related to Primary Intraosseous Squamous Cell Carcinoma Arising from Keratocystic Odontogenic Tumor ...
Squamous odontogenic tumor (SOT): a benign neoplasm of the periodontium. A review of 36 reported cases. Philipsen, H P; ... Calcifying epithelial odontogenic tumour: biological profile based on 181 cases from the literature. Philipsen, H P; Reichart, ... Immunoprofile of the adenomatoid odontogenic tumor. Reichart, P A; Philipsen, H P; Khongkhunthian, P; Sciubba, J J. ... Clear cell calcifying epithelial odontogenic tumor. A case report. Schmidt-Westhausen, A; Philipsen, H P; Reichart, P A. ...
... circumscribed epithelial tumors that most commonly arise in the suprasellar region. . ... and calcifying odontogenic cyst suggests an odontogenic epithelial differentiation for these tumors. [11] Collision lesions of ... In elderly persons, squamous metaplasia of adenohypophyseal cells of the pituitary stalk or gland has been postulated as a ... Tumor Spread and Staging. Craniopharyngiomas are World Health Organization (WHO) grade I tumors. However, rare cases of ...
Squamous odontogenic tumor (morphologic abnormality). Code System Preferred Concept Name. Squamous odontogenic tumor ( ... Squamous odontogenic tumor Active Synonym false false 195199012 Squamous odontogenic tumour Active Synonym false false ...
Odontogenic Cysts and Tumors flashcards taken from chapter 15 of the book Oral and Maxillofacial Pathology. ... extensive squamous metaplasia with keratin formation within epithelial islands (acanthomatous type). *epithelial cells with ... There is debate over reclassification of the odontogenic keratocyst (OKC) as keratocystic odontogenic tumor (KCOT). What are ... Oral and Maxillofacial Pathology: Chapter 15: Odontogenic Cysts and Tumors Flashcards. Cards. ...
Adenomatoid odontogenic tumor. *Squamous odontogenic tumor. Anterior maxilla. Composite Complex Odontoma. Posterior maxilla. ... Extra-oral lesions, swellings, and tumors of the head and neck region too come to the attention of the dentist first. Some ... Most Common Sites of Some Important Pathologies : Oral Cancer, Cysts, Tumors etc. ...
Squamous odontogenic tumour. Main article: Squamous odontogenic tumour. See also. *Bone tumours. ... NEGATIVE FOR ODONTOGENIC KERATOCYSTIC TUMOUR (ODONTOGENIC KERATOCYST). Keratocystic odontogenic tumour. Main article: ... Adenomatoid odontogenic tumour. Main article: Adenomatoid odontogenic tumour. Ameloblastic fibroma. General. *Paedatric ... Keratocystic odontogenic tumour - keratinized epithelium.. *Plasma cell neoplasm[4] - should be considered if the lesion is not ...
Feline Inductive Odontogenic Tumor (FIOT). Malignant oral tumors. Nontonsillar Squamous Cell Carcinoma (SCC) ...
Squamous odontogenic tumor-like proliferation in a radicular cyst: A case report. J Clin Exp Dent. 5(5) e298 - e301 2013. PMID ... Primary intraosseous squamous cell carcinoma arising from keratocystic odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral ... pathological entities that share similar histological characteristics with PCs include squamous odontogenic tumors and non- ... Odontogenic cysts and tumors. Ann Plast Surg. 82(4) 469 - 477 2019. PMID: 30856625. DOI: 10.1097/SAP.0000000000001738 Pubmed , ...
... keratocystic odontogenic tumor). Malignant lesions constituted 2.38%, of which squamous cell carcinoma was the most common ... The results showed high frequency of odontogenic keratocyst (keratocystic odontogenic tumor) which is not in agreement with ... The most frequent lesions were in the group of reactive lesions (22.51%), followed by odontogenic cysts. The most frequent ... lesion was radicular cyst and odontogenic keratocyst ( ...
An odontogenic tumor.. adenoangiosarcoma: An angiosarcoma involving gland structures.. adenoblast: A proliferating embryonic ... An adenocarcinoma in which some or the majority of the cells exhibit squamous differentiation. ... 1. A benign tumor of glandular origin or with a gland-like cell arrangement. 2. A benign tumor with the structure or appearance ... 1. A tumor composed of connective tissue containing glandular structures. 2. A benign neoplasm composed of glandular and ...
Squamous Odontogenic Proliferation With Probable Origin From the Rests of Malassez (Early Squamous Odontogenic Tumor?) ... Microbiology of Acute and Chronic Maxillary Sinusitis Associated with an Odontogenic Origin ...
The most common oral tumors in pets are melanoma, squamous cell carcinoma, and odontogenic fibromas. ... Oral tumors - Most common in older pets, oral tumors can become infected and tissue necrosis can occur, leading to a persistent ...
Epithelial tumors of penis - squamous adenocarcinoma cell carcinoma with variants of penis (closed to accrual) 18. Squamous ... Odontogenic malignant tumors 22. Pancreatic neuroendocrine tumor (PNET) (formerly named: Endocrine carcinoma of pancreas and ... Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03 ... Cell tumor of the testes and extragonadal germ tumors: A) Seminoma and testicular sex cord cancer B) Non seminomatous tumor C) ...
7. Odontogenic cysts 8. Oral pathology 9. Salivar glands: anatomy and pathology 10. Benign tumors of the soft tisuises of head ... Oral squamous cell carcinoma 12. Reconstructive surgery in the head and neck patient 13. Oral and maxillofacial traumatology ... The purpose of the course is to remark the relevance of an early diagnosis in squamous cell carcinoma of head and neck; to ... Benign and malignant tumors of paranasal sinuses.. - Pharynx anatomy and physiology. Acute and chronic tonsillitis. ...
Epithelial tumors of penis - squamous adenocarcinoma cell carcinoma with variants of penis (closed to accrual) 18. Squamous ... Odontogenic malignant tumors 22. Pancreatic neuroendocrine tumor (PNET) (formerly named: Endocrine carcinoma of pancreas and ... Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03 ... Cell tumor of the testes and extragonadal germ tumors: A) Seminoma and testicular sex cord cancer B) Non seminomatous tumor C) ...
Epithelial tumors of penis - squamous adenocarcinoma cell carcinoma with variants of penis (closed to accrual) 18. Squamous ... Odontogenic malignant tumors 22. Pancreatic neuroendocrine tumor (PNET) (formerly named: Endocrine carcinoma of pancreas and ... Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03 ... Cell tumor of the testes and extragonadal germ tumors: A) Seminoma and testicular sex cord cancer B) Non seminomatous tumor C) ...
Malignant melanoma, squamous cell carcinoma, and fibrosarcoma are the most common. Odontogenic tumors (arising from remnants of ... What is An Oral Tumor?. In general, the term tumor applies to any type of abnormal growth. Tumors are categorized as benign or ... a benign odontogenic tumor will require 1 cm margins, whereas for malignant tumors 2 cm margins are recommended. ... Types of Oral Tumors in Dogs & Cats. In dogs, malignant tumors were the most diagnosed pathology in biopsy samples submitted to ...
Common dog oral tumors include. *Squamous cell carcinoma. *Melanoma. *Peripheral odontogenic fibromas ... Oral tumors. Oral tumors or cancer growth may lead to unpleasant dog breath, particularly common in senior dogs. ... As the cancerous masses grow larger, they become contaminated, and parts of the tumor start dying (necrose), which causes bad ...
Kuttners Tumor is a IgG4 Associated Disease. Identification of Human Papilloma Virus in Basaloid Squamous Cell Carcinoma and ... BRAF VE1 Immunoreactivity Distinguishes Ameloblastoma from Keratocystic Odontogenic Tumor and Dentigerous Cyst, and Correlates ... Solitary Fibrous Tumor of the Head and Neck: Institutional Experience of Two Referral Centers Identification of Sox2 as a ... Adenoma Vs Carcinoid Tumor of the Middle Ear: A Study of 48 Cases and Review of the Literature. ...
Odontogenic Cyst, Calcifying [C04.557.695.605] * Odontogenic Tumor, Squamous [C04.557.695.607] * Odontoma [C04.557.695.610] ... Odontogenic Cysts (1967-1993). Odontogenic Tumors (1966-1993). Public MeSH Note. 94. History Note. 94. Date Established. 1994/ ... Odontogenic Cyst, Calcifying Preferred Term Term UI T054679. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1994). ... Odontogenic Cyst, Calcifying Preferred Concept UI. M0027568. Scope Note. A mixed radiolucent-radiopaque lesion of the jaws with ...
Soft Tissue Tumors All categories of soft tissue tumors have been reported to involve the upper aerodigestive tract. These ... A careful search for a squamous component to the tumor or overlying squamous dysplasia should be made and the identification of ... and may contain odontogenic epithelium (retrocuspid papule).4 Some mesenchymal cells of the gingiva may have a pluripotent ... FIBROBLASTIC/MYOFIBROBLASTIC TUMORS. Fibroblastic or myofibroblastic tumors make up the majority of soft tissue tumors of the ...
02 with Odontogenic Myxoma, 01 patient with Adenomatoid Odontogenic Tumor, 01 patient with Pindborg tumour and 02 patient had ... In two patients the failure of the bone graft was due the recurrence of the squamous cell carcinoma which also got secondarily ... Pindborg tumour, adenomatoid odontogenic tumour, central giant cell granuloma, odontogenic myxoma were included and the cystic ... Left mandibular defect in a 14 year-old boy following removal of a keratocystic odontogenic tumor. The inferior alveolar nerve ...
squamous odontogenic t. a benign epithelial odontogenic t. thought to arise from the epithelial cell rests of Malassez; appears ... tumor - tumor, *neoplasm, malignancy, cancer can all denote an abnormal growth or mass of tissue. Tumor, the most general term ... tumor - (Del lat. tumor, ōris). m. Med. Masa de células transformadas, con crecimiento y multiplicación anormales. tumor ... tu·mor or chiefly Brit tu·mour t(y)ü-mər n an abnormal benign or malignant new growth of tissue that possesses no ...
  • Squamous cell carcinoma arising in a residual odontogenic cyst: case report. (autopsyandcasereports.org)
  • 14 Oliveira JA, Costa IM, Loyola AM. Squamous odontogenic tumor-like proliferations (SOT-LP) versus intraosseous squamous cell carcinoma in residual cyst. (autopsyandcasereports.org)
  • Oral malignant melanoma, oral squamous cell carcinoma, and T3 tumors had the highest prevalence of metastatic disease at the time of staging. (avma.org)
  • Epithelial tumors of nasal cavity, sinuses, nasopharynx: A) Squamous cell carcinoma with variants of nasal cavity, sinuses, and nasopharynx and trachea (excluding laryngeal, nasopharyngeal cancer [NPC], and squamous cell carcinoma of the head and neck [SCCHN]) B) Adenocarcinoma and variants of nasal cavity, sinuses, and nasopharynx (closed to accrual 07/27/2018) 2. (sncrf.org)
  • Squamous cell carcinoma with variants of GI tract (stomach small intestine, colon, rectum, pancreas) (closed to accrual 10/17/2018) 7. (sncrf.org)
  • Rare pancreatic tumors including acinar cell carcinoma, mucinous cystadenocarcinoma or serous cystadenocarcinoma. (sncrf.org)
  • Epithelial tumors of penis - squamous adenocarcinoma cell carcinoma with variants of penis (closed to accrual) 18. (sncrf.org)
  • Squamous cell carcinoma variants of the genitourinary (GU) system 19. (sncrf.org)
  • Pancreatic neuroendocrine tumor (PNET) (formerly named: Endocrine carcinoma of pancreas and digestive tract. (sncrf.org)
  • The vast majority of oral malignancies are squamous cell carcinoma . (librepathology.org)
  • Complete removal - as may transform to squamous cell carcinoma or ameloblastoma . (librepathology.org)
  • Periapical cysts (PCs) belong to the inflammatory odontogenic cysts sub-category and rarely squamous cell carcinoma arises from their hyperplastic/ dysplastic epithelia. (cancerdiagnosisprognosis.org)
  • These histopathological characteristics rarely form an eligible substrate for squamous cell carcinoma onset in untended cases. (cancerdiagnosisprognosis.org)
  • Although rare, primary intraosseous squamous cell carcinoma arises from their hyperplastic/dysplastic epithelia in untended, misdiagnosed cases ( Oral Surg Oral Med Oral Pathol Oral Radiol 120(5) (2015)">3 , J Cancer Res Ther 16(3) (2020)">4 ). (cancerdiagnosisprognosis.org)
  • The most common oral tumors in pets are melanoma, squamous cell carcinoma, and odontogenic fibromas. (townecentrevet.com)
  • This phase II trial studies how well Ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor AZD6738 works alone or in combination with olaparib or durvalumab in treating participants with renal cell carcinoma (RCC), urothelial carcinoma, all pancreatic cancers, endometrial cancer, and other solid tumors excluding clear cell ovarian cancer that have spread to nearby tissue or lymph nodes or other parts of the body. (ucbraid.org)
  • Malignant melanoma, squamous cell carcinoma, and fibrosarcoma are the most common. (animaldentalaz.com)
  • The malignant oral neoplasms are diagnosed in 32-37% of cases, with squamous cell carcinoma being the most frequent, followed by fibrosarcoma, osteosarcoma and malignant melanoma. (animaldentalaz.com)
  • Variability in the Depth of Invasion Measurements of Oral Tongue Squamous Cell Carcinoma and the Effect on Pathologic T-Staging. (headandneckpathology.com)
  • Caltabiano R, Cappellani A, Di Vita M, Lanzafame S. The unique simultaneous occurrence of a squamous cell carcinoma and a granular cell tumor of the tongue at the same site: a histological and immunohistochemical study. (medscape.com)
  • Podoplanin expression in oral squamous cell carcinoma has been associated with the presence of lymph node metastasis and worst patient prognosis. (fapesp.br)
  • The sample will be constituted of 100 patients with oral squamous cell carcinoma on the lower lip, clinical stages I, II and III, treated in the Department of Head and Neck Surgery and Othorhinolaryngology of the A.C. Camargo Hospital, São Paulo, from 1970 to 2008. (fapesp.br)
  • An aggressive variant of cervical squamous cell carcinoma characterized by the presence of nests of malignant basaloid squamous cells with scant amount of cytoplasm. (nih.gov)
  • Basaloid squamous cell carcinoma of the head and neck: clinicopathological features and differential diagnosis. (nih.gov)
  • Basaloid squamous cell carcinoma of the head and neck. (nih.gov)
  • Significance of SOX2 in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: An Immunohistochemical Study. (annoordentalcollege.org)
  • Immunohistochemical Expression of Fascin in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma. (annoordentalcollege.org)
  • Immunohistochemical expression of cyclooxygenase-2 in oral squamous cell carcinoma. (annoordentalcollege.org)
  • Expression levels of RANKL assessed by western blotting were markedly lower in ameloblastoma (AM-1) cells than in highly metastatic oral squamous cell carcinoma (HSC-3) cells. (elsevierpure.com)
  • Basal cell carcinoma (BCC) is a nonmelanocytic skin cancer (ie, an epithelial tumor) that arises from basal cells (ie, small, round cells found in the lower layer of the epidermis). (medscape.com)
  • The most common tumor of the mandible and maxilla is squamous cell carcinoma invading the bone through dental sockets. (msdmanuals.com)
  • Paranasal sinus squamous cell carcinoma incidence and survival based on Surveillance, Epidemiology, and End Results data, 1973 to 2009. (ucdenver.edu)
  • Ogawa K, Toita T, Kakinohana Y, Adachi G, Kojya S, Itokazu T, Shinhama A, Matsumura J, Murayama S. Postoperative radiotherapy for squamous cell carcinoma of the maxillary sinus: analysis of local control and late complications. (ucdenver.edu)
  • Genetic factors play a role in the development of cutaneous squamous-cell carcinoma. (cdc.gov)
  • Inherited phenotypic characteristics - such as light skin, red or blonde hair, and light-colored eyes - are associated with an increased risk of cutaneous squamous-cell carcinoma. (cdc.gov)
  • A family history of cutaneous squamous-cell carcinoma is associated with a risk that is two to four times that in persons without a family history. (cdc.gov)
  • Inherited disorders such as xeroderma pigmentosum also increase the risk of cutaneous squamous-cell carcinoma, often with an earlier age at onset. (cdc.gov)
  • In rare cases, squamous odontogenic tumor-like proliferation (SOT-LP) can be observed arising from odontogenic cysts (SOT-LPOC). (autopsyandcasereports.org)
  • Squamous odontogenic tumor and squamous odontogenic tumor-like proliferations in odontogenic cysts: an updated analysis of 170 cases reported in the literature. (autopsyandcasereports.org)
  • Squamous odontogenic tumor-like proliferations in radicular cysts: a clinicopathologic study of forty-two cases. (autopsyandcasereports.org)
  • 5 Wright JM Jr. Squamous odontogenic tumorlike proliferations in odontogenic cysts. (autopsyandcasereports.org)
  • Squamous odontogenic tumors arising in odontogenic cysts. (autopsyandcasereports.org)
  • Squamous odontogenic tumor-like proliferations in periapical cysts. (autopsyandcasereports.org)
  • What are the two classes of odontogenic cysts? (easynotecards.com)
  • Most Common Sites of Some Important Pathologies : Oral Cancer, Cysts, Tumors etc. (dentaldevotee.com)
  • This article covers odontogenic tumours and cysts , which is a subset of oral pathology and can be grouped under the heading of head and neck pathology . (librepathology.org)
  • Common odontogenic cysts are dentigerous cysts , and radicular cysts . (librepathology.org)
  • Metastases in odontogenic cysts: literature review and case presentation. (librepathology.org)
  • Morphologic analysis of odontogenic cysts with computed tomography. (librepathology.org)
  • Neoplastic potential of odontogenic cysts. (librepathology.org)
  • Background/Aim: Odontogenic cysts belong to a type of lesions with endodontic origin that in some cases mimic even aggressive odontogenic tumors sharing with them similar radiographic features. (cancerdiagnosisprognosis.org)
  • Among lesions with endodontic origin, odontogenic cysts are frequently identified and clinically categorized as developmental and inflammatory ( StatPearls [Internet] (2022)">1 ). (cancerdiagnosisprognosis.org)
  • The most frequent lesions were in the group of reactive lesions (22.51%), followed by odontogenic cysts. (bvsalud.org)
  • Lesions are non-encapsulated with islands of well differentiated squamous epithelium that commonly contain microcysts and calcifications in a dense fibrous connective tissue stroma. (wikipedia.org)
  • Microscopically, SOT shows islands of squamous epithelium supported by fibrous stroma. (autopsyandcasereports.org)
  • [ 12 ] Complex sellar lesions consisting of pituitary adenoma intimately admixed with Rathke cyst and metaplastic squamous epithelium have also been reported. (medscape.com)
  • Transforms into squamous epithelium. (librepathology.org)
  • Squamous epithelium - non-keratinized - important . (librepathology.org)
  • Keratocystic odontogenic tumour - keratinized epithelium. (librepathology.org)
  • Squamous epithelium. (librepathology.org)
  • Histologically, PCs demonstrate a non-keratinized stratified squamous epithelium as a formation of one or two thin cell layers combined with fibrous connective tissue substrate infiltrated by inflammatory cells. (cancerdiagnosisprognosis.org)
  • The Odontogenic Keratocyst is known for its aggressiveness, high recurrence rate and transformation of keratinized epithelia to non-keratinized squamous epithelium for which inflammation has been suggested to be responsible. (uwi.edu)
  • The masses were covered with a thin stratified squamous epithelium. (biomedcentral.com)
  • Ameloblastoma belongs to the benign epithelial odontogenic tumor subgroup, and it is probably one of the most controversial and enigmatic tumors of the facial skeleton, due to both clinical behavior and histological features [ 1 - 10 ]. (hindawi.com)
  • Acanthomatous ameloblastoma (AA) also presents histological features very similar to those of the squamous odontogenic tumor from which it differs since the peripheral cells are columnar instead of flat [ 9 ]. (hindawi.com)
  • A View of Adenomatoid Odontogenic Tumor in Ameloblastoma: A Hybrid Variant. (annoordentalcollege.org)
  • Ameloblastoma is the most common benign odontogenic tumor in Japan. (elsevierpure.com)
  • Ameloblastoma and adenomatoid odontogenic tumor: the role of alpha2beta1, alpha3beta1, and alpha5beta1 integrins in local invasiveness and architectural characteristics. (ufrn.br)
  • Ameloblastoma, the most common epithelial odontogenic tumor, usually arises in the posterior mandible. (msdmanuals.com)
  • The cyst was excised, and histopathologic examination revealed an odontogenic keratocyst (OKC). (easynotecards.com)
  • There is debate over reclassification of the odontogenic keratocyst (OKC) as keratocystic odontogenic tumor (KCOT). (easynotecards.com)
  • The most frequent lesion was radicular cyst and odontogenic keratocyst (keratocystic odontogenic tumor). (bvsalud.org)
  • The results showed high frequency of odontogenic keratocyst (keratocystic odontogenic tumor) which is not in agreement with other studies and need more evaluation of etiological factors. (bvsalud.org)
  • These lesions can be confused with oral tumors and should be diagnosed as soon as possible after being noticed. (animaldentalaz.com)
  • Epulis is a non-specific term connoting a tumour-like mass of the gingiva and the term is used in association with several different gingival lesions, regardless of their aetiology or histogenesis [ 1 ]. (biomedcentral.com)
  • 9 Sala-Pérez S, Marco-Molina V, Gay-Escoda C. Squamous odontogenic tumor-like proliferation in a radicular cyst: a case report. (autopsyandcasereports.org)
  • 11 Unal T, Gomel M, Gunel O. Squamous odontogenic tumor-like islands in a radicular cyst: report of a case. (autopsyandcasereports.org)
  • The close histopathologic and immunohistochemical resemblance among adamantinomatous craniopharyngioma, adamantinoma of the jaw, and calcifying odontogenic cyst suggests an odontogenic epithelial differentiation for these tumors. (medscape.com)
  • What is the most common type of developmental odontogenic cyst? (easynotecards.com)
  • Histologic predictors of response to neoadjuvant PD1 inhibitor therapy in advanced stage HPV-negative head and neck squamous cell carcinomas. (headandneckpathology.com)
  • Primary and recurrent head and neck squamous carcinomas are strikingly different regarding their immune microenvironment. (headandneckpathology.com)
  • How phenotype guides management of non-conventional squamous cell carcinomas of the larynx? (nih.gov)
  • 90% of head and neck cancers are squamous cell (epidermoid) carcinomas. (msdmanuals.com)
  • The incidence of keratinocyte cancer (basal cell and squamous cell carcinomas of the skin) is 17-fold lower in Singapore than the UK, despite Singapore receiving 2-3 times more ultraviolet (UV) radiation. (cdc.gov)
  • This is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor activity of MDNA11 alone or in combination with a checkpoint inhibitor in patients with advanced solid tumors. (ucbraid.org)
  • This is an open-label, two-part, phase 1-2 dose-finding study designed to determine the safety, tolerability, PK, PD, and proof-of-concept efficacy of ST101 administered IV in patients with advanced solid tumors. (ucbraid.org)
  • Squamous odontogenic tumors (SOTs) are very rare benign locally infiltrative odontogenic neoplasms of epithelial origin. (wikipedia.org)
  • This phase I trial identifies the best dose, possible benefits and/or side effects of BAY 1895344 in combination with chemotherapy in treating patients with solid tumors or urothelial cancer that has spread to other places in the body (advanced). (ucbraid.org)
  • Combining BAY 1895344 with chemotherapy treatment (cisplatin, or cisplatin and gemcitabine) may be effective for the treatment of advanced solid tumors, including urothelial cancer. (ucbraid.org)
  • This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb23104, to describe safety and tolerability, to assess PK and immunogenicity, and to preliminarily assess anti-tumor activity of XmAb23104 monotherapy and combination therapy with ipilimumab in subjects with selected advanced solid tumors. (ucbraid.org)
  • This clinical trial is evaluating a drug called BT5528 alone and in combination with nivolumab in participants with advanced solid tumors historically known for expression of EphA2. (uci.edu)
  • I. To evaluate the Response Evaluation Criteria in Solid Tumors (RECIST) version (v)1.1 overall response rate (ORR) in subsets of patients with advanced rare cancers treated with ipilimumab plus nivolumab combination immunotherapy. (clinicaltrialsgps.com)
  • Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03/30/2018) 14. (sncrf.org)
  • Cell tumor of the testes and extragonadal germ tumors: A) Seminoma and testicular sex cord cancer B) Non seminomatous tumor C) Teratoma with malignant transformation (closed to accrual) 17. (sncrf.org)
  • Malignant giant cell tumors 30. (sncrf.org)
  • Perivascular epithelioid cell tumor (PEComa) 39. (sncrf.org)
  • 1. A benign tumor of glandular origin or with a gland-like cell arrangement. (wordquests.info)
  • BAY 1895344 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. (ucbraid.org)
  • e The pattern listed is for the spindled cell component of the tumor. (basicmedicalkey.com)
  • Vered M, Carpenter WM, Buchner A. Granular cell tumor of the oral cavity: updated immunohistochemical profile. (medscape.com)
  • Granular cell tumor: a review and update. (medscape.com)
  • Eagle syndrome produced by a granular cell tumor. (medscape.com)
  • Granular cell tumor of the tongue in a 6-year-old girl--a case report. (medscape.com)
  • Multiple granular cell tumor: a case report and review of the literature. (medscape.com)
  • Dive A, Dhobley A, Fande PZ, Dixit S. Granular cell tumor of the tongue: Report of a case. (medscape.com)
  • Granular cell tumor: immunohistochemical assessment of inhibin-alpha, protein gene product 9.5, S100 protein, CD68, and Ki-67 proliferative index with clinical correlation. (medscape.com)
  • Oral granular cell tumors: a clinicopathologic and immunocytochemical study. (medscape.com)
  • Freitas VS, dos Santos JN, Oliveira MC, Santos PP, Freitas Rde A, de Souza LB. Intraoral granular cell tumors: clinicopathologic and immunohistochemical study. (medscape.com)
  • Clinical photograph of a granular cell tumor on the tongue of a 38-year-old man. (medscape.com)
  • Granular cell tumor. (medscape.com)
  • Congenital oral granular cell tumour of the newborn is an uncommon benign tumour of uncertain origin. (biomedcentral.com)
  • The diagnosis was congenital granular cell tumour. (biomedcentral.com)
  • Congenital oral granular cell tumour occurs almost exclusively in Caucasian newborns but also rarely in black infants. (biomedcentral.com)
  • The differential diagnosis included congenital granular cell tumour (CGCT), odontogenic tumour, teratoma, neuroectodermal tumour, haemangioma and fibroma with a provisional diagnosis of CGCT. (biomedcentral.com)
  • Benign tumour of mesenchymal origin. (librepathology.org)
  • A mixed tumor of odontogenic origin, in which both the epithelial and mesenchymal cells exhibit complete differentiation, resulting in the formation of tooth structures. (uchicago.edu)
  • Context: Mesenchymal odontogenic tumors arise from the remnants of the mesenchymal portion of tooth germ. (amhsr.org)
  • Malignant mesenchymal tumors of the head and neck. (umfhs.rs)
  • Most common odontogenic tumour - considered to be a hamartoma . (librepathology.org)
  • Odontoma, the most common odontogenic tumor, affects the dental follicle or the dental tissues and usually appears in the mandibles of young people. (msdmanuals.com)
  • Cisplatin and gemcitabine are chemotherapy drugs that stop the growth of tumor cells by killing the cells. (ucbraid.org)
  • Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. (ucbraid.org)
  • The en bloc excision of the lesion was directly performed under local anesthesia and after antibiotic prophylactic regimen (amoxicillin+clavulanic acid, 2 gr p. os, 1 hour before surgery) involving the overlying keratinized tissue and the 2 contiguous teeth, with a few millimeters of lateral and apical clinically healthy tissue and about 2 mm of residual bone cavity curettage. (hindawi.com)
  • Conversely, oral tumors can present clinically as an ulcer or a non-healing extraction site, and not with a typical lump-like lesion. (animaldentalaz.com)
  • If not initially detected on x-ray, jaw tumors are diagnosed clinically because their growth causes swelling of the face, palate, or alveolar ridge (the part of the jaw supporting the teeth). (msdmanuals.com)
  • Management of a rare case of peripheral squamous odontogenic tumor of the gingiva. (autopsyandcasereports.org)
  • Peripheral nerve sheath tumors and NF1-related tumors (closed to accrual 09/19/2018) 29. (sncrf.org)
  • In order to evaluate different neo-angiogenesis levels inside malignant tissues derived from oral and odontogenic epithelia, many studies have focused on cluster differentiation 34 (CD34) protein expression combined with micro vessel density (MVD) in them ( Asian Pac J Cancer Prev 12(2) (2011)">5 - Acta Odontol Scand 68(5) (2010)">9 ). (cancerdiagnosisprognosis.org)
  • An adenocarcinoma in which some or the majority of the cells exhibit squamous differentiation. (wordquests.info)
  • Salivary gland type tumors of head and neck, lip, esophagus, stomach, trachea and lung, breast and other location (closed to accrual) 4. (sncrf.org)
  • Overview of Head and Neck Tumors Head and neck cancer develops in almost 65,000 people in the United States each year. (msdmanuals.com)
  • The head and neck regions were constituted to have high anatomical and functional difficulties, making the accurate diagnosis and staging of regional tumors a challenging task. (springeropen.com)
  • MRI sequences provided us with very accurate data about tumor size, site, and morphological criteria of tumors in the head and neck areas. (springeropen.com)
  • Adrenal cortical tumors (closed to accrual 06/27/2018) 32. (sncrf.org)
  • This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. (sncrf.org)
  • Not Otherwise Categorized (NOC) Rare Tumors [To obtain permission to enroll in the NOC cohort, contact: [email protected]] (closed to accrual 03/15/2019) 34. (sncrf.org)
  • Benign tumors may be observed and may not need surgical excision, although most tumors require resection with possible reconstruction. (msdmanuals.com)
  • Epithelial tumors of major salivary glands (closed to accrual 03/20/2018) 3. (sncrf.org)
  • Extrahepatic cholangiocarcinoma and bile duct tumors (closed to accrual 03/20/2018) 11. (sncrf.org)
  • Trophoblastic tumor: A) Choriocarcinoma (closed to accrual) 15. (sncrf.org)
  • Gastrointestinal stromal tumor (GIST) (closed to accrual 09/26/2018) 38. (sncrf.org)
  • Apocrine tumors/extramammary Paget's disease (closed to accrual) 40. (uci.edu)
  • Endometrial carcinosarcoma (malignant mixed Mullerian tumors) (closed to accrual) 45. (uci.edu)
  • 1. A tumor composed of connective tissue containing glandular structures. (wordquests.info)
  • Oral tumors - Most common in older pets, oral tumors can become infected and tissue necrosis can occur, leading to a persistent foul odor. (townecentrevet.com)
  • Even though a benign tumor is not necessarily fatal, it can have an aggressive growth pattern and can cause severe tissue damage and pain. (animaldentalaz.com)
  • All categories of soft tissue tumors have been reported to involve the upper aerodigestive tract. (basicmedicalkey.com)
  • These tumors have markedly different prognoses and require different treatments than those for soft tissue tumors. (basicmedicalkey.com)
  • Fibroblastic or myofibroblastic tumors make up the majority of soft tissue tumors of the aerodigestive tract and range from nonneoplastic or benign proliferations (fibromas) to high-grade malignancies (undifferentiated high-grade pleomorphic sarcomas). (basicmedicalkey.com)
  • I. To evaluate the association of tumor mutational burden measured by tissue sequencing with durable response (complete response [CR] or partial response [PR] lasting 24 weeks or more). (clinicaltrialsgps.com)
  • Squamous Odontogenic Tumor: Literature Review Focusing on the Radiographic Features and Differential Diagnosis. (wikipedia.org)
  • Typically, these tumors are excised, particularly when the diagnosis is in doubt. (msdmanuals.com)
  • Congenital epulis is an uncommon benign gingival tumour of the newborn. (biomedcentral.com)
  • Lymph node metastasis was diagnosed with CT or cytology in 7.5% of cases (10.7% of nonodontogenic tumors, 0% of odontogenic tumors). (avma.org)
  • Lymphatic metastasis was diagnosed in 10.7% of nonodontogenic tumors, but cytology was not performed in the majority of cases and often included only a single mandibular node. (avma.org)
  • In dogs , malignant tumors were the most diagnosed pathology in biopsy samples submitted to the lab, found in about 37% of cases. (animaldentalaz.com)
  • 2. A benign tumor with the structure or appearance of a gland or originating in a gland. (wordquests.info)
  • A benign tumor is one that has a slower growth rate and does not metastasize to the regional lymph nodes or other organs. (animaldentalaz.com)
  • Squamous odontogenic tumor (SOT) is a rare benign neoplasm of the jaw that likely arises from remnants of the dental lamina. (autopsyandcasereports.org)
  • some tumors are discovered on routine dental x-rays, whereas others are found on routine examinations of the oral cavity and teeth. (msdmanuals.com)
  • In elderly persons, squamous metaplasia of adenohypophyseal cells of the pituitary stalk or gland has been postulated as a possible origin for the papillary variant of craniopharyngioma. (medscape.com)
  • Bone lysis was present in 74.4% of tumors. (avma.org)
  • bone and cartilagenous tumors will be discussed in Chapter 12 ). (basicmedicalkey.com)
  • Interestingly, in some cases they mimic odontogenic tumors due to similar and non-discriminating radiographic features. (cancerdiagnosisprognosis.org)
  • Postoperative radiation can also be a useful adjunct when patients have aggressive tumors that were treated surgically or when surgery has failed to clear the margins of the tumor. (medscape.com)