Diseases of the nail plate and tissues surrounding it. The concept is limited to primates.
Separation of nail plate from the underlying nail bed. It can be a sign of skin disease, infection (such as ONYCHOMYCOSIS) or tissue injury.

Matched case-control phase 2 study to evaluate the use of a frozen sock to prevent docetaxel-induced onycholysis and cutaneous toxicity of the foot. (1/6)

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Unilateral taxane-induced onychopathy in a patient with a brain metastasis. (2/6)

Chemotherapy using taxanes have been useful in the treatment of several types of solid tumors. Nail abnormalities have been reported primarily with the use of docetaxel, but also with low dose, weekly paclitaxel. We report a patient with 20-nail onycolysis associated with the use of paclitaxel that resolved after stopping the medication and then recurred after the use of docetaxel, but spared all the nails of a paretic hand.  (+info)

Painful nail lesions. (3/6)

A man, 58 years of age, presented with a 4 year history of painful lesions of his nails. His previous history included hypertension, diabetes mellitus and hyperlipidaemia. These were treated with enalapril, metformin and simvastatin respectively. He also had asymptomatic skin lesions for over 15 years that had worsened in the past 4 years. His father had similar nail lesions that had been diagnosed as onychomycosis.  (+info)

Bazex syndrome (acrokeratosis paraneoplastica) diagnosed in a patient with oral persistent ulcerations. (4/6)

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Docetaxel-induced nail toxicity: a case of severe onycholysis and topic review. (5/6)

Docetaxel is a commonly-used anti-cancer chemotherapeutic agent given its efficacy in a large variety of solid tumors. It is associated with various adverse effects one of which is nail toxicity. We report a case of severe onycholysis as a result of treatment with docetaxel in a patient who suffered from metastatic nasopharyngeal carcinoma. The case report will be followed by a discussion on the possible mechanism and preventive strategies for taxane-induced nail toxicity.  (+info)

Unilateral onycholysis in a patient taking erlotinib (Tarceva). (6/6)

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Nail diseases, also known as onychopathies, refer to a group of medical conditions that affect the nail unit, which includes the nail plate, nail bed, lunula, and surrounding skin (nail fold). These diseases can be caused by various factors such as fungal infections, bacterial infections, viral infections, systemic diseases, trauma, and neoplasms.

Some common examples of nail diseases include:

1. Onychomycosis - a fungal infection that affects the nail plate and bed, causing discoloration, thickening, and crumbling of the nail.
2. Paronychia - an infection or inflammation of the nail fold, caused by bacteria or fungi, resulting in redness, swelling, and pain.
3. Ingrown toenails - a condition where the nail plate grows into the surrounding skin, causing pain, redness, and infection.
4. Onycholysis - a separation of the nail plate from the nail bed, often caused by trauma or underlying medical conditions.
5. Psoriasis - a systemic disease that can affect the nails, causing pitting, ridging, discoloration, and onycholysis.
6. Lichen planus - an inflammatory condition that can affect the skin and nails, causing nail thinning, ridging, and loss.
7. Melanonychia - a darkening of the nail plate due to pigmentation, which can be benign or malignant.
8. Brittle nails - a condition characterized by weak, thin, and fragile nails that easily break or split.
9. Subungual hematoma - a collection of blood under the nail plate, often caused by trauma, resulting in discoloration and pain.
10. Tumors - abnormal growths that can develop in or around the nail unit, ranging from benign to malignant.

Accurate diagnosis and treatment of nail diseases require a thorough examination and sometimes laboratory tests, such as fungal cultures or skin biopsies. Treatment options vary depending on the underlying cause and may include topical or oral medications, surgical intervention, or lifestyle modifications.

Onycholysis is a medical term that refers to the separation or lifting of the nail plate from the nail bed. This condition usually starts at the free edge of the nail and progresses towards the cuticle. It can affect one or more nails, and it's often characterized by the presence of loose, white, or opaque nail material.

The causes of onycholysis are varied, including trauma, infection (such as fungal infections), inflammatory skin conditions, exposure to chemicals, certain medications, and systemic diseases like psoriasis or thyroid disorders. Proper diagnosis is essential for determining the underlying cause and selecting appropriate treatment.

... is a common medical condition characterized by the painless detachment of the nail from the nail bed, usually ... The word onycholysis comes from onycho-, from Ancient Greek ὄνυξ ónuks 'nail', and Ancient Greek λύσις lúsis 'lysis/ ... Onycholysis can occur in many conditions, including psoriasis. In thyrotoxicosis, it is thought to be due to sympathetic ... ISBN 978-0-7817-8160-2. Mayon-White, R. T.; Hodgson, G. (1971-08-07). "Acute onychia and onycholysis due to an enzyme detergent ...
Jadhav VM, Mahajan PM, Mhaske CB (2009). "Nail pitting and onycholysis". Indian J Dermatol Venereol Leprol. 75 (6): 631-3. doi: ... Onycholysis Onychomadesis Onychomatricoma Onychophagia (nail biting) Onychophosis Onychoptosis defluvium (alopecia unguium) ...
Revuz J, Pouget F (1983). "[Photo-onycholysis caused by Apurone]". Annales de Dermatologie et de Venereologie (in French). 110 ...
783 Onycholysis List of cutaneous conditions James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the ...
Using dermoscopy, dermatologists found point-like hemorrhages and onycholysis (letting go of the nail) in a patient who ... Bakos RM, Bakos L (December 2006). "Use of dermoscopy to visualize punctate hemorrhages and onycholysis in "playstation thumb ...
In severe cases, the nails may separate from the nail bed (onycholysis) or become misshapen and distorted. Negative impact on ... Endonyx onychomycosis is characterized by leukonychia along with a lack of onycholysis or subungual hyperkeratosis. Candidal ...
Other side effects include alopecia, stomatitis, diarrhea, nausea, vomiting, fluid retention, onycholysis, and skin toxicity. ...
Nails can also become thickened (onychogryphosis), loosened (onycholysis), infected with fungus (onychomycosis), or degenerate ...
Psoriasis can also cause changes to the nails, such as pitting or separation from the nail bed, onycholysis, hyperkeratosis ... Ridging or pitting of fingernails or toenails (onycholysis), which is associated with psoriasis and psoriatic arthritis. ... onycholysis). Enthesitis is observed in 30 to 50% of patients and most commonly involves the plantar fascia and Achilles' ...
Nails may be separated from the nail bed (onycholysis) and may have green stripes from repeated infections. Chronic fungal ...
Nails become thick, discolored, and brittle, and often onycholysis (painless separation of nail from nail bed) occurs. More ...
It evaluates several signs separately, each on a 1-3 scale: pitting, Beau's lines, subungual hyperkeratosis and onycholysis. A ...
PCT is characterized by onycholysis and blistering of the skin in areas that receive higher levels of exposure to sunlight. The ...
... often presents with other nail conditions such as onycholysis, koilonychia, pachyonychia, Muehrcke's lines, ...
... may often present with paronychia, ingrown nail, onycholysis, pyogenic granuloma, nail-plate dystrophy ...
Onycholysis is a loosening of the exposed portion of the nail from the nail bed, usually beginning at the free edge and ...
... is a clinical sign in which there is onycholysis, or separation of the nail from the nail bed, particularly ...
... onycholysis, rash, milia, increased nail growth, pruritus (itch), and hypertrichosis. Photosensitivity leads to burning, ...
... fever Onat syndrome Onchocerciasis Oncocytoma Ondine's curse Oneirophobia Onychocryptosis Onychogryphosis Onycholysis ...
... with the affected nail showing subungual hyperkeratosis and onycholysis.: 662 : 1026 Nail Anatomy List of cutaneous conditions ...
... distal onycholysis, skeletal abnormalities, with brachydactyly, short stature, and medullary narrowing of digits. Palmoplantar ...
... onycholysis), and crumbling of the nail. In addition to the appearance and distribution of the rash, specific medical signs may ...
The pressure of the blood blister may cause separation of nail plate from the nail bed (onycholysis), but the nail should not ...
Onycholysis is a common medical condition characterized by the painless detachment of the nail from the nail bed, usually ... The word onycholysis comes from onycho-, from Ancient Greek ὄνυξ ónuks nail, and Ancient Greek λύσις lúsis lysis/ ... Onycholysis can occur in many conditions, including psoriasis. In thyrotoxicosis, it is thought to be due to sympathetic ... ISBN 978-0-7817-8160-2. Mayon-White, R. T.; Hodgson, G. (1971-08-07). "Acute onychia and onycholysis due to an enzyme detergent ...
Onycholysis is characterized by a spontaneous separation of the nail plate starting at the distal free margin and progressing ... Onycholysis is a nail disorder frequently encountered by dermatologists. ... Nonmicrobial factors in onycholysis (may be encountered at the job site, ie, as occupational onycholysis) are as follows:. * ... Endogenous factors in onycholysis. Systemic diseases and states in onycholysis are as follows:. * Amyloid and multiple myeloma ...
Understand onycholysis, a condition where the nails detach from the nail bed. Learn about its causes, symptoms, and available ... Onycholysis Overview Nail lifting (onycholysis) is the spontaneous separation (detachment) of the fingernail or toenail from ... As displayed in this image, in onycholysis, the nail is lifted from the nail bed and appears white or yellow. ... Onycholysis has many causes, including psoriasis, fungal nail infection, or a reaction to a medication. ...
Onycholysis. « Back to Glossary Index. Onycholysis is a condition that occurs when the fingernail or toenail separates from the ... Onycholysis can be caused by various factors, such as trauma or injury to the nail, frequent exposure to water or certain ... Symptoms of onycholysis may include a visible gap between the nail and the nail bed, discoloration of the affected area, pain, ... If you suspect you have onycholysis, it is advisable to consult a healthcare professional or a dermatologist who can provide an ...
For those of you unfamiliar with the condition, onycholysis is a separating of the nail from the nail bed. I noticed it first ... How I Resolved My Case of Onycholysis. by Felicia on June 14, 2013 ...
Photo-onycholysis. Photo-onycholysis is a separation or lifting of the nail plate from the nail bed in people taking an oral ...
What is Onycholysis? Symptoms, Causes, Treatment, Pictures. This is a common nail problem in which your nail separates from ... Onycholysis Causes. There are many different reasons that a person may experience onycholysis. Some of the causes may be:. *The ... Onycholysis Symptoms. When a person has onycholysis there can be a variety of symptoms, which vary from person to person. Some ... Onycholysis Treatment. Treating onycholysis is quite simple but it can be a slow process. Exactly which treatment will be used ...
Onycholysis Treatment. Onycholysis is the detachment of the nail from the nail bed - a painful and somewhat unsightly problem… ...
Photodynamic onycholysis: first report of photo-onycholysis after photodynamic therapy.. S Hanneken, U Wessendorf, N J Neumann ...
Onycholysis refers to the detachment of nails from the nail bed. It is a condition where the nails separate and lift off from ... Onycholysis can result in the nails becoming discolored, thickened, or brittle. Treatment involves addressing the underlying ...
Onycholysis Onycholysis is partial separation of the nail plate from the nail bed or complete nail plate loss. It can result ... People with onycholysis are at risk of infection with yeast and fungus. Keeping the nail dry and applying antifungal ... See also Overview of Nail Disorders.) The photo on the left shows green nail syndrome with onycholysis of the fourth... read ... Drugs may cause other nail problems, such as melanonychia striata (brown or black pigmented lines) and onycholysis. Different ...
Onycholysis (American Osteopathic College of Dermatology) * Paronychia (American Academy of Family Physicians) Also in Spanish ...
Dermatologic - Warm, moist, fine skin; sweating; fine hair; onycholysis; vitiligo; alopecia; pretibial myxedema ...
Pharm Foot OnyPlasma - Onycholysis with Colostrum Click here for more info. Pharm Foot Collagen Power - Collagen Serum with Tea ... Home›Pharm Foot›Pharm Foot Sets›Pharm Foot Package 5- Onycholysis and Damaged Nail Structures ... Pharm Foot Package 5- Onycholysis and Damaged Nail Structures. Pharm Foot Septi Starter - Refreshing Spray with antibacterial ... Pharm Foot Package 5- Onycholysis and Damaged Nail Structures. Status: Out of stock ...
Localised model-based active controlling of blood flow during chemotherapy to prevent nail toxicity and onycholysis ...
... onycholysis* (10%), and hyperphosphatemia.. *Included within onycholysis. ^Included within dry eye. ... onycholysis (41%), alanine aminotransferase increased (41%), alkaline phosphatase increased (41%), sodium decreased (40%), ...
Nail changes (e.g. Onycholysis, brittle nails, grooves). *Nails become more brittle and grow more quickly in pregnancy ( ...
onycholysis, separation of the nail from the nail bed. *crumbling *discoloration. *blood streaks ...
Included within onycholysis. ^Included within dry eye.. An adverse reaction with a fatal outcome in 1% of patients was acute ... onycholysis (41%), alanine aminotransferase increased (41%), alkaline phosphatase increased (41%), sodium decreased (40%), ...
Onycholysis, or separation of the nail bed, may also occur. Interestingly, these characteristic nail changes are observed in ...
Surface of nail plate appears rough and pitted, reddish spots, onycholysis.. Term. Nail Pterygium. ...
Passier A, Smits-van Herwaarden A, van Puijenbroek E. Photo-onycholysis associated with the use of doxycycline. BMJ. 2004;329: ... Frequency not reported: Nail discoloration, phototoxicity, photoallergic reaction, morbilliform rash, onycholysis, pustular ...
Paronychia includes nail infection, nail toxicity, onychoclasis, onycholysis, onychomadesis, paronychia.. Þ Dry skin includes ...
Includes onycholysis, onychoclasis, nail disorder, nail dystrophy, nail ridging, and onychomadesis. § Includes dry skin and ...
Onycholysis, splinter hemorrhage, and oil drop were significantly more common in the PsA group as opposed to patients with just ... The most common nail abnormality was onycholysis, followed by pitting and oil droplet changes. Nail involvement was more common ... Onycholysis, splinter hemorrhage, and oil drop were significantly more common in the PsA group as opposed to patients with just ... The most common nail abnormality was onycholysis, followed by pitting and oil droplet changes. Nail involvement was more common ...
Onycholysis - Nail separation from the nail bed.. Youve likely seen your fair share of nails stained yellow after the removal ...
Nail separation, or onycholysis is characterized by total or partial separation of the finger or toenail for the nail bed. It ... Finger and toenail onycholysis. J Eur Acad Dermatol Venereol. 29. 5; 848-853, 2015 ...
  • Photodynamic onycholysis: first report of photo-onycholysis after photodynamic therapy. (qxmd.com)
  • Photo-onycholysis may be seen. (logicalimages.com)
  • Patients with hepatocellular dysfunction may develop hair-thinning or hair loss and nail changes such as clubbing, leukonychia (whitening), or onycholysis, affecting the nails of the hands and feet. (wikipedia.org)
  • Nails with onycholysis usually are smooth, firm, and without inflammatory reaction. (medscape.com)
  • This image displays nails that have separated from the nail bed, caused by onycholysis. (skinsight.com)
  • Onycholysis refers to the detachment of nails from the nail bed. (proprofs.com)
  • Onycholysis can result in the nails becoming discolored, thickened, or brittle. (proprofs.com)
  • The nails may separate from the nail bed (onycholysis). (docpods.com)
  • In addition to pitting of the nail surface, this patient with psoriasis has a yellowish discoloration and separation of the nail plate from the nail bed (onycholysis) of the free edges of the nails. (skinsight.com)
  • You might feel like you need to reach for the clippers every other day during your pregnancy, but some expectant mamas experience other nail woes, including white lines or dots (leukonychia), splitting, brittleness, ingrown nails, detachment (onycholysis) and thickening. (whattoexpect.com)
  • For instance, the wrong nail hardener and harsh acetone nail polish removers render the nails dry and cracky, increasing the risk of onycholysis. (imaginail.com)
  • Onychomycosis (tinea) It is common in ballet dancers Chemotherapy (cytotoxic agents like taxanes, vinca alkaloids and others) Chronic Renal Failure Most instances of onycholysis without a clear cause will heal spontaneously within a few weeks. (wikipedia.org)
  • The aim of treatment is also to eliminate onychomycosis that is a major cause of onycholysis. (wikipedia.org)
  • For onychomycosis, one of the primary end points recommended by the FDA is complete cure, which is achieved when there is a total lack of clinical evidence of onychomycosis (including lack of onycholysis and subungual hyperkeratosis). (medpagetoday.com)
  • Onycholysis can occur in many conditions, including psoriasis. (wikipedia.org)
  • Onycholysis has many causes, including psoriasis, fungal nail infection, or a reaction to a medication. (skinsight.com)
  • This image displays onycholysis (lifting of the nail) caused by psoriasis. (skinsight.com)
  • Onycholysis can be caused by various factors, such as trauma or injury to the nail, frequent exposure to water or certain chemicals, fungal infections, psoriasis, thyroid disease, or underlying medical conditions. (thetoenailclinicnyc.com)
  • This image displays a separation of the nail from the bed (onycholysis) caused by psoriasis. (skinsight.com)
  • Pitting and onycholysis are visible on the hand (right), suggesting nail psoriasis as the diagnosis. (merckmanuals.com)
  • There are many different reasons that a person may experience onycholysis. (healthool.com)
  • Many acrylic nail users experience onycholysis at least once in their lives. (imaginail.com)
  • All patients underwent dermatological examination by a dermatologist (O.Z.). The following nail changes were recorded: pitting, crumbling, onycholysis, oil drop, subungual hyperkeratosis, and splinter hemorrhage. (hindawi.com)
  • Onycholysis is a common medical condition characterized by the painless detachment of the nail from the nail bed, usually starting at the tip and/or sides. (wikipedia.org)
  • Nail lifting (onycholysis) is the spontaneous separation (detachment) of the fingernail or toenail from the nail bed at the end of the nail (distal) and/or on the sides of the nail (lateral). (skinsight.com)
  • Onycholysis is characterized by a spontaneous separation of the nail plate starting at the distal free margin and progressing proximally. (medscape.com)
  • In a condition called onycholysis, the fingernails come loose and can separate from the nail bed. (mayoclinic.org)
  • Onycholysis is a condition that occurs when the fingernail or toenail separates from the nail bed, the area where it is attached to the finger or toe. (thetoenailclinicnyc.com)
  • The two main types of onycholysis are distal and proximal. (imaginail.com)
  • Onycholysis can be seen usually in the fourth and fifth fingernails. (medscape.com)
  • Onycholysis is the separation of the nail plate from the pink skin underneath, better known as the nail bed. (imaginail.com)
  • Symptoms of onycholysis may include a visible gap between the nail and the nail bed, discoloration of the affected area, pain, tenderness, or an irregular shape of the nail. (thetoenailclinicnyc.com)
  • When a person has onycholysis there can be a variety of symptoms, which vary from person to person. (healthool.com)
  • There are several conditions that have similar symptoms but when it has these two characteristics, it happens gradually and is painless, it is usually onycholysis. (healthool.com)
  • When onycholysis occurs, a coexistent yeast infection is suggested. (medscape.com)
  • Treating primary and secondary factors that exacerbate onycholysis is important. (medscape.com)
  • Treating onycholysis is quite simple but it can be a slow process. (healthool.com)
  • The photo on the left shows green nail syndrome with onycholysis of the fourth. (msdmanuals.com)
  • Onycholysis is not a disease of the nail matrix, but nail discoloration may appear underneath the nail as a result of secondary infection. (medscape.com)
  • Onycholysis can also be a sign of an infection, the result of an injury to your nail, or a sign of some skin disease. (healthool.com)
  • Depending on what is causing your case of onycholysis your nail plat may have collected underneath the edge of your nail plat thickened skin. (healthool.com)
  • Onycholysis, splinter hemorrhage, and oil drop were significantly more common in the PsA group as opposed to patients with just skin findings. (hindawi.com)
  • Thickening of skin under the nail, which can dislodge the nail (onycholysis) from the nail bed. (clevelandclinic.org)
  • Left untreated, severe cases of onycholysis may result in nail bed scarring. (medscape.com)
  • However, onycholysis can also result from nail infections like nail fungi. (imaginail.com)
  • For those of you unfamiliar with the condition, onycholysis is a separating of the nail from the nail bed. (adoseofhealth.com)
  • Finally, your onycholysis may be the result of mani-pedis gone wrong. (imaginail.com)
  • Exactly which treatment will be used depends on what caused onycholysis to happen. (healthool.com)
  • As displayed in this image, in onycholysis, the nail is lifted from the nail bed and appears white or yellow. (skinsight.com)
  • If you suspect you have onycholysis, it is advisable to consult a healthcare professional or a dermatologist who can provide an accurate diagnosis and recommend appropriate treatment options. (thetoenailclinicnyc.com)