Oral submucous fibrosis. Medical search. Web

'Oral Submucous Fibrosis' is a chronic, insidious, and potentially disabling condition, characterized by progressive stiffness and loss of elasticity of the oral mucosa, due to fibrotic changes in the lamina propria, often associated with juxta-epithelial inflammation and epithelial atrophy.

A plant genus of the family ARECACEAE. Members contain ARECOLINE and CATECHIN. The leaves and nuts have been used as masticatories, stimulants, and astringents in traditional medicine. The common name of betel is also used for PIPER BETLE. The common name of catechu is sometimes used for ACACIA CATECHU.

An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.

Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.

A salt produced by the reaction of zinc oxide with acetic acid and used as an astringent, styptic, and emetic.

One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)

A white patch seen on the oral mucosa. It is considered a premalignant condition and is often tobacco-induced. When evidence of Epstein-Barr virus is present, the condition is called hairy leukoplakia (LEUKOPLAKIA, HAIRY).

Tumors or cancer of the MOUTH.

Mechanical devices that simulate the temporomandibular joints and jaws to which maxillary and mandibular casts are attached. The entire assembly attempts to reproduce the movements of the mandible and the various tooth-to-tooth relationships that accompany those movements.

A clear, homogenous, structureless, eosinophilic substance occurring in pathological degeneration of tissues.

Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)

Inflammation of the tongue.

An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS.

Injections introduced directly into localized lesions.

Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.

I'm sorry for any confusion, but "India" is not a medical term that can be defined in a medical context. It is a geographical location, referring to the Republic of India, a country in South Asia. If you have any questions related to medical topics or definitions, I would be happy to help with those!

Oesophageal subepithelial fibrosis: an extension of oral submucosal fibrosis. (1/66)

Fifty-five patients with oral submucosal fibrosis and an equal number of patients with no evidence of the disease were studied. All patients underwent upper gastrointestinal endoscopy and any abnormality was noted. Multiple oesophageal biopsies were obtained from the upper end of the oesophagus and from any endoscopically observed abnormality. The histological changes in the two groups were assessed blindly by an experienced histopathologist. Histological abnormalities were noted in the oesophageal mucosa in 2% of controls and 66% of patients with oral submucosal fibrosis (p < 0.0001). In the control group, acanthosis was seen in one patient, while in the patient group atrophy of the squamous epithelium was evident in 52%, hyperkeratosis in 52%, parakeratosis in 30%, dyskeratosis in 14%, acanthosis in 14%, and papillomatosis and mild dysplasia in 2% patients. Subepithelial collagenization was seen in 32 (64%) patients. The oesophageal abnormalities were seen more frequently in patients who had consumed Pan masala, Gutka, betel nut, tobacco or a combination of some or all of these, with or without betel leaf, for > or = 5 years compared to those consuming them for a shorter period of time (91% vs 46%, p < 0.001). It is concluded that oral submucosal fibrosis is not a disease confined to the oral cavity; the oesophagus may also be involved in about two-thirds of patients. (+info)

Oral submucous fibrosis in a 11-year-old Bangladeshi girl living in the United Kingdom. (2/66)

A case of oral submucous fibrosis occurring in a 11-year-old Bangladeshi girl is presented. This paper reviews the aetiology, clinical presentation and treatment modalities of oral submucous fibrosis. This case highlights the link between oral submucous fibrosis and the regular use of areca-nut (paan) and the newer transcultural oral tobacco products. This association has been reported among children resident in the Indian sub-continent but is unrecorded for United Kingdom residents. The case report underlines the danger that children face with products which are clearly targeted at them by the tobacco industry. (+info)

Interaction of collagen-related genes and susceptibility to betel quid-induced oral submucous fibrosis. (3/66)

Oral submucous fibrosis (OSF) is a precancerous condition of the oral cavity. It is a collagen-related disorder induced by betel quid chewing, a habit that is common in Taiwan. However, the cumulative exposure to betel quids varies in OSF patients. It seems that there is individual susceptibility to betel quid-induced OSF. This study compared the association of OSF and polymorphisms of six collagen-related genes, collagen 1A1 and 1A2 (COL1A1 and COL1A2), collagenase-1 (COLase), transforming growth factor beta1 (TGF-beta1), lysyl oxidase (LYOXase), and cystatin C (CST3), between patients with low and high exposure to betel quids. A total of 166 patients with OSF from a medical center and 284 betel quid chewers who were free of OSF and oral cancer, from the same hospital and five townships, were recruited. PCR-based restriction fragment length polymorphism assays were used to determine the genotypes of the six collagen-related genes situated on different chromosomes. We found that the genotypes associated with the highest OSF risk for collagen 1A1, collagen 1A2, collagenase-1, transforming growth factor beta1, lysyl oxidase, and cystatin C were CC, AA, TT, CC, AA, and AA, respectively, for the low-exposure group, and TT, BB, AA, CC, GG, and AA, respectively, for the high-exposure group. A trend was noted for an increased risk of OSF with increasing number of high-risk alleles for those with both high and low exposures for betel quid. The cell selection mechanism of oral fibroblasts is proposed to explain the effect of the modification of cumulative betel quid exposure on the risk profiles of collagen-related genes. These results imply that susceptibility to OSF could involve multigenic mechanisms modified by the betel quid-exposure dose. (+info)

The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern Taiwan. (4/66)

In areas where the practise of betel quid chewing is widespread and the chewers also often smoke and drink alcohol, the relation between oral precancerous lesion and condition to the three habits is probably complex. To explore such association and their attributable effect on oral leukoplakia (OL) and oral submucous fibrosis (OSF), a gender-age-matched case-control study was conducted at Kaohsiung, southern Taiwan. This study included 219 patients with newly diagnosed and histologically confirmed OL or OSF, and 876 randomly selected community controls. All information was collected by a structured questionnaire through in-person interviews. A preponderance of younger patients had OSF, while a predominance of older patients had OL. Betel quid chewing was strongly associated with both these oral diseases, the attributable fraction of OL being 73.2% and of OSF 85.4%. While the heterogeneity in risk for areca nut chewing across the two diseases was not apparent, betel quid chewing patients with OSF experienced a higher risk at each exposure level of chewing duration, quantity and cumulative measure than those who had OL. Alcohol intake did not appear to be a risk factor. However, cigarette smoking had a significant contribution to the risk of OL, and modified the effect of chewing based on an additive interaction model. For the two oral premalignant diseases combined, 86.5% was attributable to chewing and smoking. Our results suggested that, although betel quid chewing was a major cause for both OL and OSF, its effect might be difference between the two diseases. Cigarette smoking has a modifying effect in the development of oral leukoplakia. (+info)

Prevalence of oral submucous fibrosis in the high natural radiation belt of Kerala, south India. (5/66)

Oral submucous fibrosis (OSMF) is a crippling disorder which is confined almost exclusively to the Indian subcontinent. Despite its association with a significantly increased risk of cancer, the etiology is still not clear. An epidemiological assessment showed 0.4% prevalence for OSMF in Kerala, South India, which is among the highest recorded. Recently the National Tumour Registry in Trivandrum reported the highest recorded site-specific incidence rate for oral cancer (ICD 140-145) in this area. The coastal belt of the Trivandrum and Quilon districts of Kerala has a very high natural radioactivity (over 1500 mR (387 microC) per year); about 500 mR (129 microC) per year is considered to be the maximum permissible dose for populations in general. An epidemiological survey in this area and in a comparable population (without exposure to high background radiation) as a control showed that the percentage prevalence of OSMF in the study area was 0.27 and in the control area 0.32. It appears highly improbable that the OSMF in the study area was induced by high background radiation. (+info)

Alterations in plasma lipid profile patterns in head and neck cancer and oral precancerous conditions. (6/66)

BACKGROUND: The changes in lipid profile have long been associated with cancer because lipids play a key role in maintenance of cell integrity. AIMS: The present study evaluated alterations in plasma lipid profile in untreated head and neck cancer patients as well as patients with oral precancerous conditions (OPC) and its association with habit of tobacco consumption. MATERIAL AND METHODS: This hospital-based case control study included 184 head and neck cancer patients, 153 patients with OPC and 52 controls. Plasma lipids including: (i) Total cholesterol, (ii) LDL cholesterol (LDLC), (iii) HDL cholesterol (HDLC) (iv) VLDL cholesterol (VLDLC) and (v) triglycerides were analysed by spectrophotometric kits. STATISTICAL ANALYSIS USED: Student's t-test was performed to compare mean values of the parameters. RESULTS: A significant decrease in plasma total cholesterol and HDLC was observed in cancer patients (P=0.008 and P=0.000 respectively) as well as in patients with OPC (P=0.014 and P=0.000, respectively) as compared to the controls. The plasma VLDL and triglycerides levels were significantly lower in cancer patients as compared to the patients with OPC (P=0.04) and controls (P=0.059). The tobacco habituates showed lower plasma lipid levels than the non-habituates. Our data strengthen the evidence of an inverse relationship between plasma lipid levels and head and neck malignancies as well as OPC. CONCLUSION: The lower levels of plasma cholesterol and other lipid constituents in patients might be due to their increased utilization by neoplastic cells for new membrane biogenesis. The findings strongly warrant an in-depth study of alterations in plasma lipid profile in head neck cancer patients. (+info)

Oral mucosal lesions associated with use of quid. (7/66)

Quid is a mixture of substances that is placed in the mouth or actively chewed over an extended period, thus remaining in contact with the mucosa. It usually contains one or both of 2 basic ingredients, tobacco and areca nut. Betel quid or paan is a mixture of areca nut and slaked lime, to which tobacco can be added, all wrapped in a betel leaf. The specific components of this product vary between communities and individuals. The quid habit has a major social and cultural role in communities throughout the Indian subcontinent, Southeast Asia and locations in the western Pacific. Following migration from these countries to North America, predominantly to inner city areas, the habit has remained prevalent among its practitioners. Many dentists are unaware of the prevalence of the quid or paan habit in the Asian patient population. The recognition of the role of such products in the development of oral precancer and cancer is of great importance to the dental practitioner. A variety of oral mucosal lesions and conditions have been reported in association with quid and tobacco use, and the association of these conditions with the development of oral cancer emphasizes the importance of education to limit the use of quid. In most cases, cessation of the habit produces improvement in mucosal lesions as well as in clinical symptoms. (+info)

A novel wavelet neural network based pathological stage detection technique for an oral precancerous condition. (8/66)

AIM: To describe a novel neural network based oral precancer (oral submucous fibrosis; OSF) stage detection method. METHOD: The wavelet coefficients of transmission electron microscopy images of collagen fibres from normal oral submucosa and OSF tissues were used to choose the feature vector which, in turn, was used to train the artificial neural network. RESULTS: The trained network was able to classify normal and oral precancer stages (less advanced and advanced) after obtaining the image as an input. CONCLUSIONS: The results obtained from this proposed technique were promising and suggest that with further optimisation this method could be used to detect and stage OSF, and could be adapted for other conditions. (+info)

Oral Submucous Fibrosis (OSF) is a chronic, progressive, and potentially disabling disease that affects the oral soft tissues. It is characterized by inflammation and fibrosis (excessive deposition of collagen) of the submucosal tissues, leading to stiffness and limitation of mouth opening, tongue movement, and occasionally swallowing or speaking difficulties. The condition primarily affects individuals with a history of areca nut (betel nut) chewing, although other factors such as smoking, alcohol consumption, and genetic predisposition may also contribute to its development. Symptoms can include burning sensation in the mouth, dryness, and pain during speaking, eating, or swallowing. In severe cases, OSF can lead to significant functional impairment and require surgical intervention.

"Areca" is the term used to refer to the Areca catechu plant, which is also known as the betel nut palm. The areca nut, which is the seed of the fruit produced by this plant, is commonly chewed with betel leaf for its mild stimulant effects. It contains a number of alkaloids, including arecoline, which has psychoactive properties. Chewing areca nut is a popular habit in many parts of Asia and the Pacific Islands, despite evidence that it can have negative health effects, such as increasing the risk of oral cancer.

Arecoline is a parasympathomimetic alkaloid that is the primary active component found in the areca nut, which is chewed for its psychoactive effects in various parts of the world. It can cause stimulation of the nervous system and has been associated with several health risks, including oral cancer and cardiovascular disease.

The medical definition of Arecoline is:

A parasympathomimetic alkaloid found in the areca nut, which is chewed for its psychoactive effects. It stimulates the nervous system and has been associated with several health risks, including oral cancer and cardiovascular disease. The chemical formula for Arecoline is C7H9NO2.

The mouth mucosa refers to the mucous membrane that lines the inside of the mouth, also known as the oral mucosa. It covers the tongue, gums, inner cheeks, palate, and floor of the mouth. This moist tissue is made up of epithelial cells, connective tissue, blood vessels, and nerve endings. Its functions include protecting the underlying tissues from physical trauma, chemical irritation, and microbial infections; aiding in food digestion by producing enzymes; and providing sensory information about taste, temperature, and texture.

Zinc acetate is an inorganic compound with the chemical formula Zn(C2H3O2)2. It is a white, crystalline salt that is highly soluble in water and readily forms dihydrates. Zinc acetate is used as a dietary supplement and as a topical treatment for various medical conditions such as cold sores, throat irritations, and skin disorders.

In the medical field, zinc acetate is commonly found in lozenges and nasal sprays that are used to reduce the severity and duration of the common cold. It has been shown to have antimicrobial properties and can help to boost the immune system. Additionally, zinc acetate is also used in the treatment of Wilson's disease, a rare genetic disorder that causes copper to accumulate in the body. By binding to copper, zinc acetate helps to remove excess copper from the body.

It's important to note that excessive intake of zinc can lead to adverse effects such as nausea, vomiting, and other gastrointestinal symptoms. Therefore, it is recommended to follow the dosage instructions carefully when taking zinc acetate or any other zinc supplement.

The submucosal plexus, also known as Meissner's plexus, is a component of the autonomic nervous system located in the submucosa layer of the gastrointestinal tract. It is a network of nerve fibers and ganglia that primarily regulates local reflexes and secretions, contributing to the control of gut motility, blood flow, and mucosal transport.

Meissner's plexus is part of the enteric nervous system (ENS), which can operate independently from the central nervous system (CNS). The ENS consists of two interconnected plexuses: Meissner's submucosal plexus and Auerbach's myenteric plexus.

Meissner's plexus is responsible for regulating functions such as absorption, secretion, vasodilation, and local immune responses in the gastrointestinal tract. Dysfunction of this plexus can lead to various gastrointestinal disorders, including irritable bowel syndrome (IBS) and other motility-related conditions.

Leukoplakia, oral is a predominantly white patch or plaque that cannot be characterized clinically or pathologically as any other disease. It is an oral potentially malignant disorder (OPMD) and represents a significant risk for the development of squamous cell carcinoma. The lesions are typically caused by chronic irritation, such as smoking or smokeless tobacco use, and are most commonly found on the tongue, floor of the mouth, and buccal mucosa. The diagnosis is confirmed through a biopsy, and management includes removal of causative factors and close monitoring for any signs of malignant transformation.

A mouth neoplasm refers to an abnormal growth or tumor in the oral cavity, which can be benign (non-cancerous) or malignant (cancerous). Malignant mouth neoplasms are also known as oral cancer. They can develop on the lips, gums, tongue, roof and floor of the mouth, inside the cheeks, and in the oropharynx (the middle part of the throat at the back of the mouth).

Mouth neoplasms can have various causes, including genetic factors, tobacco use, alcohol consumption, and infection with human papillomavirus (HPV). Symptoms may include a lump or thickening in the oral soft tissues, white or red patches, persistent mouth sores, difficulty swallowing or speaking, and numbness in the mouth. Early detection and treatment of mouth neoplasms are crucial for improving outcomes and preventing complications.

A dental articulator is a mechanical device that is used in dentistry to simulate the movement and relationship of the upper and lower jaws (maxilla and mandible). It is essentially a hinge-like instrument that helps dental professionals replicate the patient's unique jaw movements and create dental restorations, such as crowns, bridges, or dentures, which fit accurately and comfortably.

Dental articulators come in various designs and complexities, but they generally consist of an upper and lower portion that represent the maxilla and mandible, respectively. These portions are connected by an adjustable arm, called a condylar element, which mimics the temporomandibular joint (TMJ) movement. This allows for the simulation of different jaw movements, such as opening, closing, protrusion, and lateral excursions.

By using a dental articulator, dentists can precisely design, adjust, and verify the fit, form, and function of dental restorations before placing them in the patient's mouth. This helps ensure optimal occlusal (bite) relationships, improved aesthetics, and increased patient comfort and satisfaction.

'Hyalin' is not a medical condition or disease, but rather a histological term used to describe a particular type of tissue structure. Hyalin refers to the homogeneous, translucent, and eosinophilic (pink) appearance of a tissue under a microscope due to the accumulation of an amorphous, acellular, and protein-rich matrix.

Hyalinization can occur in various tissues, including blood vessels, cardiac valves, cartilage, and other connective tissues. It is often associated with aging, injury, inflammation, or degenerative changes, such as those seen in hyaline membrane disease (a respiratory disorder in premature infants) or hypertrophic cardiomyopathy (thickening of the heart muscle).

In summary, Hyalin is a histological term used to describe the appearance of tissue under a microscope due to the accumulation of an amorphous, acellular, and protein-rich matrix.

A precancerous condition, also known as a premalignant condition, is a state of abnormal cellular growth and development that has a higher-than-normal potential to progress into cancer. These conditions are characterized by the presence of certain anomalies in the cells, such as dysplasia (abnormal changes in cell shape or size), which can indicate an increased risk for malignant transformation.

It is important to note that not all precancerous conditions will eventually develop into cancer, and some may even regress on their own. However, individuals with precancerous conditions are often at a higher risk of developing cancer compared to the general population. Regular monitoring and appropriate medical interventions, if necessary, can help manage this risk and potentially prevent or detect cancer at an early stage when it is more treatable.

Examples of precancerous conditions include:

1. Dysplasia in the cervix (cervical intraepithelial neoplasia or CIN)
2. Atypical ductal hyperplasia or lobular hyperplasia in the breast
3. Actinic keratosis on the skin
4. Leukoplakia in the mouth
5. Barrett's esophagus in the digestive tract

Regular medical check-ups, screenings, and lifestyle modifications are crucial for individuals with precancerous conditions to monitor their health and reduce the risk of cancer development.

Glossitis is a medical term that refers to inflammation of the tongue. This condition can cause symptoms such as swelling, redness, pain, and smoothness or discoloration of the tongue's surface. Glossitis can have various causes, including nutritional deficiencies (such as vitamin B12 or folate deficiency), allergic reactions, infections (bacterial, viral, or fungal), irritants (such as hot and spicy foods, alcohol, or tobacco), and autoimmune disorders (such as pemphigus vulgaris or lichen planus). Treatment for glossitis depends on the underlying cause.

I'm sorry for any confusion, but "Hyaluronoglucosaminidase" appears to be a made-up term or a typographical error. The correct term related to hyaluronic acid metabolism is "hyaluronidase," which is an enzyme that degrades hyaluronic acid, a component of the extracellular matrix in various tissues. If you meant to ask about this enzyme or its functions, I'd be happy to provide more information on that. However, if "Hyaluronoglucosaminidase" is intended to represent another medical term, could you please clarify so I can provide an accurate and helpful response?

"Intralesional injection" is a medical term that refers to the administration of a medication directly into a lesion or skin abnormality, such as a tumor, cyst, or blister. This technique is used to deliver the medication directly to the site of action, allowing for higher local concentrations and potentially reducing systemic side effects. Common examples include the injection of corticosteroids into inflamed tissues to reduce swelling and pain, or the injection of chemotherapeutic agents directly into tumors to shrink them.

Connective tissue is a type of biological tissue that provides support, strength, and protection to various structures in the body. It is composed of cells called fibroblasts, which produce extracellular matrix components such as collagen, elastin, and proteoglycans. These components give connective tissue its unique properties, including tensile strength, elasticity, and resistance to compression.

There are several types of connective tissue in the body, each with its own specific functions and characteristics. Some examples include:

1. Loose or Areolar Connective Tissue: This type of connective tissue is found throughout the body and provides cushioning and support to organs and other structures. It contains a large amount of ground substance, which allows for the movement and gliding of adjacent tissues.
2. Dense Connective Tissue: This type of connective tissue has a higher concentration of collagen fibers than loose connective tissue, making it stronger and less flexible. Dense connective tissue can be further divided into two categories: regular (or parallel) and irregular. Regular dense connective tissue, such as tendons and ligaments, has collagen fibers that run parallel to each other, providing great tensile strength. Irregular dense connective tissue, such as the dermis of the skin, has collagen fibers arranged in a more haphazard pattern, providing support and flexibility.
3. Adipose Tissue: This type of connective tissue is primarily composed of fat cells called adipocytes. Adipose tissue serves as an energy storage reservoir and provides insulation and cushioning to the body.
4. Cartilage: A firm, flexible type of connective tissue that contains chondrocytes within a matrix of collagen and proteoglycans. Cartilage is found in various parts of the body, including the joints, nose, ears, and trachea.
5. Bone: A specialized form of connective tissue that consists of an organic matrix (mainly collagen) and an inorganic mineral component (hydroxyapatite). Bone provides structural support to the body and serves as a reservoir for calcium and phosphate ions.
6. Blood: Although not traditionally considered connective tissue, blood does contain elements of connective tissue, such as plasma proteins and leukocytes (white blood cells). Blood transports nutrients, oxygen, hormones, and waste products throughout the body.

I'm sorry for any confusion, but "India" is not a medical term or concept. It is a country in South Asia, the second-most populous country in the world, known for its rich history, diverse culture, and numerous contributions to various fields including medicine. If you have any questions related to medical topics, I would be happy to help answer them!

"Efficacy of lycopene in the management of oral submucous fibrosis". Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology ... Most patients with oral submucous fibrosis present with moderate-to-severe disease. Severe oral submucous fibrosis is ... Oral Submucous Fibrosis at eMedicine Sharma, Mohit; Radhakrishnan, Raghu (June 2023). "Should oral submucous fibrosis be ... 3 (3): 40-9. Pindborg JJ, Sirsat SM (December 1966). "Oral submucous fibrosis". Oral Surgery, Oral Medicine, and Oral Pathology ...

https://en.wikipedia.org/wiki/Oral_submucous_fibrosis

Rao, N.R.; Villa, A.; More, C.B.; Jayasinghe, R.; Kerr, A.R.; Johnson, N.W. (2020). "Oral submucous fibrosis: a contemporary ... 2014) Chewing areca nut is a cause of oral submucous fibrosis, a premalignant lesion which frequently progresses to mouth ... Ray JG, Chatterjee R, Chaudhuri K (2019). "Oral submucous fibrosis: A global challenge. Rising incidence, risk factors, ... "Reasons for Initiation of Areca Nut and Related Products in Patients with Oral Submucous Fibrosis within an Endemic Area in ...

https://en.wikipedia.org/wiki/Areca_nut

The nut itself can be addictive and has direct link to oral cancers. Chewing areca nut is a cause of oral submucous fibrosis, a ... Ray JG, Chatterjee R, Chaudhuri K (2019). "Oral submucous fibrosis: A global challenge. Rising incidence, risk factors, ... Hemantha Amarasinghe (2010). "Betel-quid chewing with or without tobacco is a major risk factor for oral potentially malignant ... disorders in Sri Lanka: A case-control study". Oral Oncology. 46 (4): 297-301. doi:10.1016/j.oraloncology.2010.01.017. PMID ...

https://en.wikipedia.org/wiki/Areca_catechu

Lasers are also used in treating oral submucous fibrosis. Palliative laser therapy is given in advanced oesophageal cancers ... The CO2 laser is used in oral and dental surgery for virtually all soft-tissue procedures, such as gingivectomies, ... ISBN 978-0-470-34412-5. Strauss, Robert (2017-03-08). "24". In Fonseca, Raymond J. (ed.). Oral and Maxillofacial Surgery - E- ... and oral and maxillofacial surgery) as well as veterinary surgical fields. The primary uses of lasers in soft tissue surgery ...

https://en.wikipedia.org/wiki/Laser_surgery

Sirsat, Satyavati M.; Pindborg, J. J. (1967). "The Vascular Response in Early and Advanced Oral Submucous Fibrosis". Acta ... Her research, which focused on oral submucous fibrosis, was published in Nature, Carcinogenesis, Tumori Journal, Journal of ... ISBN 978-81-237-8144-0. Sirsat, Satyavati M.; Kandarkar, S. V. (June 1968). "Histological changes in the oral mucosa of the ...

https://en.wikipedia.org/wiki/Satyavati_Motiram_Sirsat

Use of Areca nut is associated with oral submucous fibrosis. An appearance termed Betel chewer's mucosa describes morsicatio ... Oral snuff causes more pronounced changes in the oral mucosa than tobacco chewing. Snuff dipping is associated more with ... The differential diagnosis includes other oral white lesions such as Leukoplakia, squamous cell carcinoma, oral candidiasis, ... As well as the white changes of the oral mucosa, there may be gingival recession (receding gums) and staining of tooth roots in ...

https://en.wikipedia.org/wiki/Smokeless_tobacco_keratosis

Other common premalignant lesions include oral submucous fibrosis and actinic cheilitis. In the Indian subcontinent oral ... 2014). Textbook of Oral Medicine, Oral Diagnosis and Oral Radiology. Elsevier India. p. 387. ISBN 978-8131230916. "The Oral ... "The utility of oral brush cytology in the early detection of oral cancer and oral potentially malignant disorders: A systematic ... Oral cancer is the sixteenth most common cancer in the UK (around 6,800 people were diagnosed with oral cancer in the UK in ...

https://en.wikipedia.org/wiki/Oral_cancer

It causes Oral Submucous Fibrosis by stimulating collagen, interleukin 6, keratinocyte growth factor-1, IGF-1, cystatin C, ... Yusuf H, Yong SL (July 2002). "Oral submucous fibrosis in a 12-year-old Bangladeshi boy: a case report and review of literature ... Cox S, Ullah M, Zoellner H (January 2016). "Oral and systemic health effects of compulsive areca nut use.". In Preedy VR (ed ... Betel quid without tobacco causes oral cancer. There is sufficient evidence in experimental animals for the carcinogenicity of ...

https://en.wikipedia.org/wiki/Arecoline

Neoplastic: ● Oral Submucous Fibrosis: This is a condition that involves inflammation of the tissues under the surface. This ... Oral Manifestations of Systemic Diseases at eMedicine Squier, Christopher A.; Kremer, Mary J. (2001). "Biology of Oral Mucosa ... It accounts for 60% of oral mucosa. Secretion - Saliva is the primary secretion of the oral mucosa. It has many functions ... 2011). Human Oral Mucosa. doi:10.1002/9781118710470. ISBN 9781118710470. Nanci (2013). Ten Cate's Oral Mucosa. Elsevier. p. 278 ...

https://en.wikipedia.org/wiki/Oral_mucosa

... is known to cause severe oral mucosal disorders. Oral submucous fibrosis, one such disorder, is a malignant condition that is ... Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. Oral Surgery, Oral edicine, Oral Pathology, ... Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109:857-64. Javed F, Bello Correa FO, Chotai M, Tappuni AR, Almas K. ... Smokeless tobacco use is most common in India where oral cancer accounts for 30 to 40% of cancer cases. Its use has been ...

https://en.wikipedia.org/wiki/Gutka

... oral submucous fibrosis), are more likely to turn malignant. Although overall, oral cancer is more common in males, females ... Conditions associated with mucosal atrophy include iron deficiency, some vitamin deficiencies, oral submucous fibrosis, ... Oral leukoplakia is a potentially malignant disorder affecting the oral mucosa. It is defined as "essentially an oral mucosal ... Almost all oral white patches are usually the result of keratosis. For this reason, oral white patches are sometimes generally ...

https://en.wikipedia.org/wiki/Leukoplakia

Oral submucous fibrosis and lichen planus, which are generally accepted to be precancerous conditions, appear to be related to ... A Scoping Review of the Association between Different Betel Quid Ingredients and the Risk of Oral Submucous Fibrosis". ... found that oral cancer was the 6th most common cancer among males, and 10th among females. Of these oral carcinoma patients, 36 ... "Oral cancer in Myanmar: A preliminary survey based on hospital-based cancer registries". Journal of Oral Pathology & Medicine. ...

https://en.wikipedia.org/wiki/Betel_nut_chewing

... fibrosis of temporalis tendon, when patient has limited mouth opening, always premalignant conditions like oral submucous ... Needle prick to the medial pterygoid muscle Oral submucous fibrosis. Radiation therapy to the head and neck. Tetanus, also ... Submucous fibrosis. Fracture of the zygomatic arch. Acute osteomyelitis Ankylosis of the TMJ (fibrous or bony) Condylar ... Oral surgery procedures, as in the extraction of lower molar teeth, may cause trismus as a result either of inflammation to the ...

https://en.wikipedia.org/wiki/Trismus

For instance, native fluorescence of a FAD and NADH is varied in normal tissue and oral submucous fibrosis, which is an early ... and nicotinamide adinine dinucleotide/flavin adenine dinucleotide reduction and oxidation states of oral submucous fibrosis for ... sign of invasive oral cancer. Doctors therefore have been employing fluorescence to assist in diagnosis and monitor treatment ...

https://en.wikipedia.org/wiki/Flavin_adenine_dinucleotide

Ghada A. Abd El Latif, Tumor necrosis factor alpha and keratin 17 expression in oral submucous fibrosis in rat model, E.D.J. ... Both protein molecules tumor necrosis factor alpha and keratin 17 appear to be related in case of oral submucous fibrosis In ...

https://en.wikipedia.org/wiki/Tumor_necrosis_factor

Oral submucous fibrosis Pachydermodactyly Palisaded encapsulated neuroma Paraneoplastic syndrome Pearly penile papules ( ... Nagayama's spots Oral Crohn's disease Oral florid papillomatosis Oral melanosis Osseous choristoma of the tongue Peripheral ... Phanuphak N (2006). "Skin lesions: mirror images of oral lesion infections". Adv. Dent. Res. 19 (1): 69-72. doi:10.1177/ ... Ismail SB; Kumar SK; Zain RB (2007). "Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and ...

https://en.wikipedia.org/wiki/List_of_skin_conditions

Oral lichen planus Oral lichenoid lesions Oral squamous cell carcinoma Oral submucous fibrosis Oral-facial cleft Oral-facial- ... atrophy dementia Oral facial digital syndrome type 3 Oral facial digital syndrome type 4 Oral facial digital syndrome Oral ... digital syndrome, type IV Oral-facial-digital syndrome Oral-pharyngeal disorders Organic brain syndrome Organic mood syndrome ...

https://en.wikipedia.org/wiki/List_of_diseases_(O)

... congenita ductal carcinoma in situ lobular carcinoma in situ Sclerosing adenosis Small duct papilloma oral submucous fibrosis ... Precancerous conditions of the skin or oral cavity can appear as visible lesions without associated pain or discomfort, while ... Yardimci G, Kutlubay Z, Engin B, Tuzun Y (December 2014). "Precancerous lesions of oral mucosa". World Journal of Clinical ... Neville BW, Day TA (July 2002). "Oral cancer and precancerous lesions". CA: A Cancer Journal for Clinicians. 52 (4): 195-215. ...

https://en.wikipedia.org/wiki/Precancerous_condition

... a nonprofit foundation that promotes open geospatial data Oral submucous fibrosis, a medical condition This disambiguation page ...

https://en.wikipedia.org/wiki/OSMF

... polymorphism in oral submucous fibrosis and head and neck lesions.Chaudhary AK, Singh M, Bharti AC, Singh M, Shukla S, Singh AK ...

https://en.wikipedia.org/wiki/Matrix_metalloproteinase

... can cause premalignant lesions such as leukoplakia and submucous fibrosis, and are recognized risk factors for oral and ... Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 116 (4): 433-439. doi:10.1016/j.oooo.2013.05.021. PMID 23969334 ... This is known as intra-oral halitosis, oral malodour or oral halitosis. The most common causes are odour producing biofilm on ... Intra-oral halitosis Extra-oral halitosis A. Blood borne halitosis (i) Systemic diseases (ii) Metabolic diseases (iii) Food (iv ...

https://en.wikipedia.org/wiki/Bad_breath

https://en.wikipedia.org/wiki/Oral_submucous_fibrosis

Joshi subsequently coined the termed oral submucous fibrosis (OSF) for the condition in 1953. ... Schwartz coined the term atrophica idiopathica mucosa oris to describe an oral fibrosing disease he discovered in 5 Indian ... Efficacy of lycopene in the management of oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Feb. ... encoded search term (Oral Submucous Fibrosis) and Oral Submucous Fibrosis What to Read Next on Medscape ...

https://emedicine.medscape.com/article/1077241-overview

https://reference.medscape.com/article/1077241-overview

Oral submucous fibrosis--a chronic disseminated intravascular coagulation syndrome with local coagulopathy. ... Oral submucous fibrosis--a chronic disseminated intravascular coagulation syndrome with local coagulopathy. ...

https://gut.bmj.com/content/34/5/713.1

A case-control study on chewing and smoking habits and oral submucous fibrosis (OSF) was undertaken in Karachi in 1989/90. ... Role of areca nut in the causation of oral submucous fibrosis: a case-control study in Pakistan J Oral Pathol Med. 1994 Feb;23( ... A case-control study on chewing and smoking habits and oral submucous fibrosis (OSF) was undertaken in Karachi in 1989/90. ... Oral Submucous Fibrosis / complications * Oral Submucous Fibrosis / epidemiology * Oral Submucous Fibrosis / etiology* ...

https://pubmed.ncbi.nlm.nih.gov/8164155/?dopt=Abstract

Return to Article Details UNRAVELING ABERRANT MICROENVIRONMENT IN ORAL SUBMUCOUS FIBROSIS Download Download PDF ...

https://www.jptcp.com/index.php/jptcp/article/view/2634/2631

https://emedicine.dev01.medscape.com/article/1077241-differential

Oral Submucous Fibrosis. Departments: Oral Medicine And Radiology Oral submucous fibrosis (OSF) is a chronic, complex, ... the jaws become rigid to the point that the sufferer is unable to open his mouth.The condition is linked to oral cancers and is ... highly potent pre-cancerous condition characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the ...

https://midac.in/treatments/oral-submucous-fibrosis/

https://reference.dev01.medscape.com/article/1077241-overview

Home » Mental health Blogs » Oral submucous fibrosis and malignant transformation. Oral submucous fibrosis and malignant ... Oral submucous is a persistent oral mucosal illness thats certainly one of a gaggle of circumstances recognised as oral ... EC Malignant transformation fee of oral submucous fibrosis: A scientific evaluate and meta-analysis. Oral Surg. 2022; 00: 1- 8 ... Malignant transformation in oral submucous fibrosis: Tertiary degree proof: An umbrella evaluate. Oral Dis. 2023 Aug 31. doi: ...

https://thespiritualmental.com/oral-submucous-fibrosis-and-malignant-transformation/

There is one such disorder known as the Oral Submucous Fibrosis is also an oral disorder which we will be discussing about in ... oral health, symptoms of oral submucous fibrosis, treatment for oral submucous fibrosis, treatment of oral submucous fibrosis ... Home Remedies Oral Health And Hygiene Oral Submucous Fibrosis Ayurvedic Management of Oral Submucous Fibrosis February 28, 2022 ... Vikram Chauhan 0 Comments ayurvedic medicines for oral submucous fibrosis, Herbal Remedies for oral submucous fibrosis, ...

https://www.planetayurveda.net/ayurvedic-management-of-oral-submucous-fibrosis/

... PubMed, SCI, Scopus, ESCI, PMC indexed ... Oral Submucous Fibrosis. 1. Background. Oral submucous fibrosis (OSF) is a chronic and latent malignant disease, which poses a ... Background: Oral submucous fibrosis (OSF) is a progressive and inflammatory mucosal fibrosis disease with cancerous tendency. ... Oral submucous fibrosis: A clinicopathological study of 674 cases in China. J Oral Pathol Med 48 (2019): 321-325. ...

https://www.fortunejournals.com/articles/treatment-of-oral-submucous-fibrosis-a-case-report.html

Keywords : Candida; gutkha chewing; oral carriage; oral submucous fibrosis. · abstract in Portuguese · text in English · pdf in ... ANILA, K et al. Comparative study of Candida in oral submucous fibrosis and healthy individuals. Rev. odonto ciênc. (Online) [ ... PURPOSE: Oral submucous fibrosis (OSMF) is a high-risk precancerous condition that predominantly affects Indian youngsters due ... Samples were collected with the oral rinse technique and cultured on Sabourauds agar medium. The isolated yeast species were ...

http://revodonto.bvsalud.org/scielo.php?script=sci_abstract&pid=S1980-65232011000100016&lng=en&nrm=iso&tlng=en

Oral sub mucous fibrosis is a chronic, progressive, and irreversible disease of unknown aetiology. Oral submucous fibrosis (SMF ... Epidemiological studies have identified a variety of oral mucosal lesions and conditions in association with betel quid and ...

http://www.journalcra.com/article/review-oral-submucous-fibrosis

Lost your password? Please enter your username or email address. You will receive a link to create a new password via email.. ...

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Oral submucous fibrosis is a chronic disease characterised by progressive inability to open the mouth. ... Oral Surg Oral Med Oral Pathol 22: 764-779.. *Angadi PV, Rao SS (2011) Areca nut in pathogenesis of oral submucous fibrosis: ... J Oral Pathol Med 30: 12-21.. *Kakar PK, Puri RK, Venkatachalam VP (1985) Oral submucous fibrosis--treatment with hyalase. J ... Yeh CJ (1996) Application of the buccal fat pad to the surgical treatment of oral submucous fibrosis. Int J Oral Maxillofac ...

https://www.heraldopenaccess.us/openaccess/surgical-management-of-trismus-due-to-oral-submucous-fibrosis-using-diode-laser

Bharat Agravat "Trendsetter Awards 2022", who raised vigilance on how to prevent oral cancer by OSMF Mouth Opening Kit ...

https://osmfmouthopeningkit.com/tag/director/

Leukoplakia and squamous cell carcinoma are sometimes associated with Oral Submucous Fibrosis as the predisposing factors for ... What is Oral Submucous Fibrosis? Paan and Supari Chewing are Just as Bad as Tobacco and Gutkha!. drsharadon. 14/06/2022. 24/06/ ... On a final note, I would suggest you keep a check on your body health and in case you doubt having oral submucous fibrosis, ... Leave a Comment on What is Oral Submucous Fibrosis? Paan and Supari Chewing are Just as Bad as Tobacco and Gutkha! ...

https://www.drsharadent.com/what-is-oral-submucous-fibrosis/

oral submucous, fibrosis,, Ayurveda, Hanubasti, Gandusha, Pratisarana,, berberis Abstract. The prevalence of oral submucous ... J Oral BiolCraniofac Res. 2012;2(3):159-162. Borle RM, Borle SR. Management of oral submucous fibrosis -A conservative approach ... Efficacy of Ayurveda against oral submucous fibrosis - A case study Authors. * Unnati Desai First Year PG Scholar, Department ... 2022). Efficacy of Ayurveda against oral submucous fibrosis - A case study. Parul University Journal of Health Sciences and ...

https://pujhsr.paruluniversity.ac.in/index.php/home/article/view/10

Oral Submucous Fibrosis (OSF), is a well-recognized, oral potentially malignant disorder predominantly affecting the South- ... Oral submucous fibrosis: an etiological dilemma.. Sharma, Aanchal; Kumar, Rajesh; Johar, Navdeep; Sabir, Husain. J Exp Ther ... OSF causes unique generalized fibrosis of the submucosal oral soft tissues, resulting in marked rigidity of the oral mucosa ... Fibrose Oral Submucosa/etiologia Areca/efeitos adversos Capsicum/efeitos adversos Humanos Desnutrição/complicações Óxido ...

https://pesquisa.bvsalud.org/odontologia/resource/pt/mdl-29161786

Oral submucous fibrosis (OSF) is a chronic inflammatory disease characterized by the accumulation of excess collagen, and areca ... Activation of TGF-beta Pathway by Areca Nut Constituents: A Possible Cause of Oral Submucous Fibrosis ... A Possible Cause of Oral Submucous Fibrosis. In: PLOS ONE, 7 (12). ... Oral epithelium plays important roles in OSF, and arecoline has been shown to induce TGF-beta in epithelial cells. In an ...

https://eprints.iisc.ac.in/45730/

Approximately 90% of oral cancers are squamous cell carcinoma (SCC), which is seen typically on the lip or lateral part of the ... Oral submucous fibrosis. Red patch (erythroplakia). Mixed red and white patch (erythroleukoplakia/speckled leukoplakia) ... Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 Mar. 81 (3):265-6. [QxMD MEDLINE Link]. [Full Text]. ... Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003 Aug. 96 (2):164-71. [QxMD MEDLINE Link]. ...

https://emedicine.medscape.com/article/1075729-differential

Surgical Management of Oral Submucous Fibrosis by Comparing Two Flaps: A Comparative Study * Aneela Amjad Assistant Professor ... Background: Oral submucous fibrosis is a chronic disease which is slow and progressive in nature and results in reduced mouth ... Keywords: Oral submucous fibrosis, Buccal fat pad, Nasolabial flap, inter incisal mouth opening ... Amjad, A., Akhtar, U., Zahid, N., & Chatha, A. (2017). Surgical Management of Oral Submucous Fibrosis by Comparing Two Flaps: A ...

https://apmcfmu.com/index.php/apmc/article/view/193

An improvised approach for regaining mouth opening and managing tooth wear in oral sub-mucous fibrosis. In: Journal of the ... keywords = "Occlusal splints, Oral submucous fibrosis, Orthotic devices, Tooth wear",. author = "Khan, {Farhan Raza} and Nazeer ... An improvised approach for regaining mouth opening and managing tooth wear in oral sub-mucous fibrosis. Journal of the Pakistan ... An improvised approach for regaining mouth opening and managing tooth wear in oral sub-mucous fibrosis. / Khan, Farhan Raza; ...

https://scholars.aku.edu/en/publications/an-improvised-approach-for-regaining-mouth-opening-and-managing-t

JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral ... In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol. 123, No. 6, 01.06.2017.. Research output: Contribution ... Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2017 Jun 1;123(6). doi: 10.1016/j.oooo.2017.02.019 ... In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2017 ; Vol. 123, No. 6. ...

https://researcher.manipal.edu/en/publications/clinicobiochemical-evaluation-of-turmeric-with-black-pepper-and-n

Modified platysma myocutaneous flap technique for reconstruction of oral submucous fibrosis: A tehnical note ... Comparative evaluation of reconstructive methods in oral submucous fibrosis. J Maxillofac Oral Surg. 2021;20:597-606. [CrossRef ... Tiwari P, Bera RN, Chauhan N. What is the optimal reconstructive option for oral submucous fibrosis? A systematic review and ... Modified platysma myocutaneous flap technique for reconstruction of oral submucous fibrosis: A tehnical note. ...

https://jadpr.org/modified-platysma-myocutaneous-flap-technique-for-reconstruction-of-oral-submucous-fibrosis-a-tehnical-note/

Depletion of miR-155 hinders the myofibroblast activities and reactive oxygen species generation in oral submucous fibrosis. ... Depletion of miR-155 hinders the myofibroblast activities and reactive oxygen species generation in oral submucous fibrosis. / ... Depletion of miR-155 hinders the myofibroblast activities and reactive oxygen species generation in oral submucous fibrosis. In ... keywords = "miR-155, Myofibroblast, Oral submucous fibrosis",. author = "Chou, {Ming Yung} and Fang, {Chih Yuan} and Hsieh, { ...

https://hub.tmu.edu.tw/en/publications/depletion-of-mir-155-hinders-the-myofibroblast-activities-and-rea

Journal of Oral Medicine and Oral Surgery revue de la SFCO. Elle est consacrée à l étude et au traitement des affections de la ... Efficacy of spirulina in management of oral submucous fibrosis − a systematic review J Oral Med Oral Surg 2022;28:8. ... Prevalence of oral mucosal lesions among elderly population in Chennai: a survey J Oral Med Oral Surg 2020;26:10. ... Oral potentially malignant disorders: advice on management in primary care J Oral Med Oral Surg 2022;28:36. ...

https://www.jomos.org/articles/mbcb/full_html/2022/02/mbcb210174/F4.html

EVALUATION OF DNA DAMAGE BY COMET ASSAY IN PATIENTS OF ORAL SUBMUCOUS FIBROSIS (OSMF). ...

https://eprajournals.com/IJMR/article/1009

Oral submucous fibrosis (OSMF) is a high-risk precancerous condition that predominantly affects Indian youngsters due to the habit of gutkha chewing. (bvsalud.org)
Pindborg defined OSMF as, "an insidious, chronic disease affecting any part of the oral cavity and sometimes the pharynx. (heraldopenaccess.us)
Oral submucous fibrosis (OSMF) is a chronic disease that produces tissue fibrosis and is considered to be a potentially malignant disorder. (opendentistryjournal.com)
This case report demonstrates the full mouth prosthetic rehabilitation of a patient with generalised compensated tooth wear and oral sub-mucous fibrosis (OSMF). (aku.edu)
Salivary ELISA for vimentin has been attempted to evaluate the secretion of vimentin in samples from normal healthy volunteers comparing with saliva from patients presenting with oral leukoplakia, OSMF and Oral squamous cell carcinoma. (researchsquare.com)

The malignant transformation rate of OSF to oral squamous cell carcinoma ranges from 1.2 to 23% worldwide [1-2]. (fortunejournals.com)
Leukoplakia and squamous cell carcinoma are sometimes associated with ORAL SUBMUCOUS FIBROSIS as the predisposing factors for all these disorders are common. (drsharadent.com)
Rosenquist K, Wennerberg J, Schildt EB, Bladström A, Göran Hansson B, Andersson G. Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma. (medscape.com)
Better grade of tumor differentiation of oral squamous cell carcinoma arising in background of oral submucous fibrosis. (thejcdp.com)
Oral submucous fibrosis with an exophytic, proliferative growth on the right buccal mucosa which proved to be squamous cell carcinoma on histopathological examination. (iarc.fr)
Oral tongue squamous cell carcinoma (OTSCC) is an aggressive cancer with high morbidity and mortality rates, despite multimodality management. (researchsquare.com)
Oral Tongue Squamous cell carcinoma (OTSCC) represents a major portion of oral cavity cancers, especially in India. (researchsquare.com)

[ 15 ] Commercially freeze-dried products such as pan masala, guthka, and mawa have higher concentrations of areca nut per chew and appear to cause oral submucous fibrosis more rapidly than self-prepared conventional betel quid, which contains smaller amounts of areca nut. (medscape.com)
How does eating paan cause Oral Submucous fibrosis? (drsharadent.com)

This study indicated that management of oral submucous fibrosis can be achieved surgically using diode laser with minimal morbidity and great results. (heraldopenaccess.us)
Borle RM, Borle SR. Management of oral submucous fibrosis -A conservative approach. (paruluniversity.ac.in)

Oral submucous fibrosis (OSF) is a chronic, complex, premalignant (1% transformation risk) condition of the oral cavity, characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues (the lamina propria and deeper connective tissues). (wikipedia.org)
Per Jens J. Pindborg and Satyavati Sirsat (1966, pathological definition): 'An insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx. (wikipedia.org)
Per Mohit Sharma and Raghu Radhakrishnan (2019): 'An insidious, chronic potentially malignant fibrotic disorder affecting the entire oral cavity and sometimes the pharynx and oesophagus. (wikipedia.org)
The condition is believed to begin in the posterior part of the oral cavity and gradually spread outward. (wikipedia.org)
the sites are dictated by the manner of use anterior areas of the oral cavity when spitting and posterior when swallowed. (wikipedia.org)
Oral submucous fibrosis is a chronic debilitating disease of the oral cavity characterized by inflammation and progressive fibrosis of the submucosal tissues (lamina propria and deeper connective tissues). (medscape.com)
It is a chronic and premalignant condition of the oral cavity which can affect any part of the oral cavity and also can affect the pharynx. (planetayurveda.net)
It is associated with the inflammation of the juxta epithelial inflammatory reaction which is then followed by fibroelastic changes and epithelial atrophy which causes the stiffness of the oral cavity leads to trismus and inability to eat. (planetayurveda.net)
There is a leathery feel of the oral cavity with the palpable fibrotic band and after the disease advances the oral cavity gets stiff and blanched. (planetayurveda.net)
Presence of palpable fibrous bands in buccal mucosa and/or oropharynx, and in any other parts of oral cavity, with/without stomatitis. (heraldopenaccess.us)
Scully C. The oral cavity. (paruluniversity.ac.in)
Bilateral or symmetric reticular changes with or without ulcers and erythema occurring anywhere in the oral cavity. (medscape.com)
Cancer Stat Facts: Oral Cavity and Pharynx Cancer. (medscape.com)
After this, intraorally a tunnel of the size of the pedicle is created from the buccal surface of the mandible into the neck at the lower border of the mandible and flap is transferred in the oral cavity which reaches until retromolar trigone with good pedicle length. (jadpr.org)
Smoking is a major cause of cancers of the oral cavity (tongue, lips, gums) oesophagus and larynx. (citizen-news.org)
14 cases of the oral cavity (buccal mucosa, alveolus, oral tongue and hard palate) were treated with surgery. (scirp.org)
A new classification for potentially malignant disorders of the oral cavity. (thejcdp.com)
Smokeless tobacco contains many cancer-causing toxins and its use increases the risk of cancers of the head, neck, throat, oesophagus and oral cavity (including cancer of the mouth, tongue, lip and gums) as well as various dental diseases. (who.int)
It is estimated that 35,310 (25,310 males and 10,000 females) new cases of oral cavity and pharyngeal malignancies were diagnosed in the US during 2008, while 7,590 (5,210 males and 2,380 females) patients died of this disease [ 1 ]. (biomedcentral.com)

As the disease progresses, the oral mucosa becomes fibrotic to the point that the person is unable to open the mouth. (wikipedia.org)
The oral mucosa loses resiliency in the advanced stage and becomes blanched and stiff. (wikipedia.org)
In 1952, Schwartz coined the term atrophica idiopathica mucosa oris to describe an oral fibrosing disease he discovered in 5 Indian women from Kenya. (medscape.com)
A number of factors trigger the disease process by causing a juxtaepithelial inflammatory reaction in the oral mucosa. (medscape.com)
Anemia: Pale oral mucosa can mimic atrophy and fibrosis. (medscape.com)
It can also occur with the characteristics like reduced movement and loss of papillae of the tongue, and leathery texture of the oral mucosa. (planetayurveda.net)
It was also reported that Chinese medicine formulas such as salvia/miltiorrhiza have certain effects in OSF treatment by means of activating blood circulation, removing blood stasis and softening the stiffen oral mucosa. (fortunejournals.com)
With the combined treatment of sublingual compound Danshen dropping pills and topical triamcinolone acetonide for mouth rinse, the patient achieved curative effects of obviously improved mouth opening and soften oral mucosa. (fortunejournals.com)
While the collagen deposition alters in oral mucosa, the compact tissue oppresses the capillaries and block the blood flow that produces a hypoxic environment suitable for the promotion of malignant cell growth [1-3]. (fortunejournals.com)
Pathological features include chronic inflammation, excessive collagen deposition in the submucosal connective tissue of the oral mucosa, local inflammation in the lamina propria or deep connective tissue, and degenerative changes in muscle [3-4]. (fortunejournals.com)
Although occasionally preceded by and/or associated with vesicle formation, it is always associated with juxta-epithelial inflammatory reaction followed by fibroelastic change of the lamina propria, with epithelial atrophy leading to stiffness of the oral mucosa and causing trismus and inability to eat" [2]. (heraldopenaccess.us)
Stomatitis and/or blanching of oral mucosa. (heraldopenaccess.us)
Patient complaining of restricted mouth opening with fibrous bands present over the buccal mucosa, hard palate, anterior faucial pillars or oropharynx proven histopathologically to be oral submucous fibrosis. (heraldopenaccess.us)
Distinctive features of oral cancer in Changhua County: high incidence, buccal mucosa preponderance, and a close relation to betel quid chewing habit. (medscape.com)
OSF causes unique generalized fibrosis of the submucosal oral soft tissues , resulting in marked rigidity of the oral mucosa leading to progressive inability to open the mouth , rigidity of lips and difficulty in protruding the tongue . (bvsalud.org)
The terminology presented in this report reflects our best understanding of multi-step carcinogenesis in the oral mucosa, and aspires to engender consistency in use. (nih.gov)
Oral lichen planus and lichenoid reactions are autoimmune type inflammatory conditions of the oral mucosa with similar clinical and histological characteristics. (ecancer.org)
They were 21 transformations of the oral mucosa [ 5 ] as systemically healthy adult volunteers (13 well as severe periodontitis [ 6 ]. (who.int)

A. Any one of the above stage along with other potentially malignant disorders e.g. oral leukoplakia, oral erythroplakia, etc. (heraldopenaccess.us)
An outline was proposed for diagnosing oral leukoplakia that will prevent other oral white disorders being misclassified as leukoplakia. (nih.gov)
The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern Taiwan. (ajtmh.org)
Epidemiological survey of oral submucous fibrosis and leukoplakia in aborigines of Taiwan. (ajtmh.org)
Epidemiology and histology of oral leukoplakia and leukoedema among Papuans and New Guineans. (ajtmh.org)
Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma. (thejcdp.com)

The Working Group discussed the caveats involved in the current use of terminology and classification of oral potentially malignant disorders, deficiencies of these complex systems, and how they have evolved over the past several decades. (nih.gov)
Oral potentially malignant disorders: precising the definition. (thejcdp.com)

Epidemiological studies have identified a variety of oral mucosal lesions and conditions in association with betel quid and tobacco use. (journalcra.com)
Human papillomavirus: its identity and controversial role in oral oncogenesis, premalignant and malignant lesions (review). (medscape.com)
Progress risk assessment of oral premalignant lesions with saliva miRNA analysis. (thejcdp.com)
Moreover, oral lichenoid reactions (OLR) is a term used to describe clinical and histopathological lesions similar to OLP but with an identifiable etiologic factor. (ecancer.org)

Raised keratinocyte growth factor-1 expression in oral submucous fibrosis in vivo and upregulated by arecoline in human buccal mucosal fibroblasts in vitro. (medscape.com)
Increased tissue inhibitor of metalloproteinase-1 expression and inhibition of gelatinase A activity in buccal mucosal fibroblasts by arecoline as possible mechanisms for oral submucous fibrosis. (medscape.com)
Oral submucous is a persistent oral mucosal illness that's certainly one of a gaggle of circumstances recognised as oral probably malignant problems (OPMD). (thespiritualmental.com)
Oral submucous fibrosis (OSF) is a progressive and inflammatory mucosal fibrosis disease with cancerous tendency. (fortunejournals.com)
Pathological characteristics include chronic inflammation in lamina propria or deep connective tissues with collagen deposition below the oral mucosal epithelium along with degenerative changes in the muscles [ 2 ]. (opendentistryjournal.com)

These collagen fibers are non degradable and the phagocytic activity is minimized.The role of pure capsaicin in the etiology and pathogenesis of oral submucous fibrosis has been debunked, as its has been shown to have antifibrotic and anticancer effects. (wikipedia.org)
The pathogenesis of the disease is not well established, but the cause of oral submucous fibrosis is believed to be multifactorial. (medscape.com)
The areca nut component of betel quid plays a major role in the pathogenesis of oral submucous fibrosis. (medscape.com)
Tilakaratne WM, Klinikowski MF, Saku T, Peters TJ, Warnakulasuriya S. Oral submucous fibrosis: review on aetiology and pathogenesis. (medscape.com)

Oral Oncol 2014;50:e46-e47. (thejcdp.com)
Oral Oncol 2012;48:759-760. (thejcdp.com)
Oral Oncol 2011;47:920-921. (thejcdp.com)

Oral submucosal fibrosis--a preventable disease. (bmj.com)

The condition is remotely linked to oral cancers and is associated with the chewing of areca nut and/or its byproducts, commonly practiced in South and South-East Asian countries. (wikipedia.org)
[ 15 ] but their addition to areca nut chewing can be a risk for oral submucous fibrosis. (medscape.com)
As the disease progresses, the jaws become rigid to the point that the sufferer is unable to open his mouth.The condition is linked to oral cancers and is associated with areca nut chewing, the main component of betel quid. (midac.in)
Canniff JP, Harvey W. The aetiology of oral submucous fibrosis: the stimulation of collagen synthesis by extracts of areca nut. (medscape.com)
Oral submucous fibrosis (OSF) is a chronic and latent malignant disease, which poses a global and regional problem to public health, especially in East and Southeast Asia where areca nut chewing is popular. (fortunejournals.com)
Oral submucous fibrosis (SMF) is a potentially malignant disease caused by chewing of areca nut and is associated with both significant morbidity and an increased risk for malignancy. (journalcra.com)
Oral submucous fibrosis (OSF) is a chronic inflammatory disease characterized by the accumulation of excess collagen, and areca nut chewing has been proposed as an important etiological factor for disease manifestation. (iisc.ac.in)

Oral submucous fibrosis is a chronic disease characterised by progressive inability to open the mouth. (heraldopenaccess.us)
Oral submucous fibrosis is a chronic disease which is slow and progressive in nature and results in reduced mouth opening. (apmcfmu.com)

Fibrosis of the palate and pillars. (medscape.com)

This umbrella evaluate of systematic opinions aimed to find out the proportion of oral most cancers improvement in oral submucous fibrosis sufferers. (thespiritualmental.com)
Majority of oral cancers occur because of chewing Tobacco, gutka etc. (citizen-news.org)
Among them, 154,030 OPMD cases and 23,286 oral cancers were found during the study period. (aaqr.org)
Top upregulated protein was validated using another independent set of tissue samples by Immunohistochemistry (n=346), comprising of retrospective early stage OTSCC (n=150) and prospective series of oral pre-cancers, normal and oral cancers (n=195). (researchsquare.com)
Vimentin was found to be significantly overexpressed in oral pre-cancers along with cancers compared to normal tissues. (researchsquare.com)
Salivary ELISA for vimentin can additionally be useful for disease monitoring in oral cancers. (researchsquare.com)
We have additionally studied the vimentin expression in Oral precancers and cancers comparing with normal tissues. (researchsquare.com)

Betel quid without tobacco as a risk factor for oral precancers. (medscape.com)
The prevalence of oral submucous fibrosis is steadily rising as a result of excessive betel nut chewing and tobacco usage in various forms. (paruluniversity.ac.in)
Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan. (ajtmh.org)

Oral sub mucous fibrosis is a chronic, progressive, and irreversible disease of unknown aetiology. (journalcra.com)

Chainani-Wu N, Epstein J, Touger-Decker R. Diet and prevention of oral cancer: strategies for clinical practice. (medscape.com)
Being headed by UK Trained Oral & Maxillofacial Surgeon, this department acts as a bridge between Clinical Medicine and Hospital-based dentistry. (ststephenshospital.org)

In this article, we would like to report our experience of treating 30 patients of oral sub-mucous fibrosis using diode laser and to discuss upon opting the fore-mentioned tool in the study. (heraldopenaccess.us)
In our technique, we have used a modified technique by raising a superiorly based platysma myocutaneous flap through a single incision, rather than giving two incisions and we have increased the length of the pedicle for the reconstruction of patients with oral submucous fibrosis. (jadpr.org)
The aim of the study was to assess the oral health status and hygiene habits among adult patients with respect to their level of dental anxiety. (who.int)
Oral aloe may reduce blood glucose and glycated hemoglobin (HbA1c) in patients with diabetes. (therapeuticresearch.com)

Wickham striae can mimic atrophy and fibrosis. (medscape.com)
Juxta-epithelial fibrosis occurs with atrophy or hyperplasia of the overlying epithelium, which shows areas of epithelial dysplasia. (drsharadent.com)

Khan, FR & Nazeer, MR 2023, ' An improvised approach for regaining mouth opening and managing tooth wear in oral sub-mucous fibrosis ', Journal of the Pakistan Medical Association , vol. 73, no. 8, pp. 1716-1719. (aku.edu)

A case-control study on chewing and smoking habits and oral submucous fibrosis (OSF) was undertaken in Karachi in 1989/90. (nih.gov)
Effect of tobacco, alcohol, and smoking habits in oral precancer with histological proven epithelial dysplasia. (paruluniversity.ac.in)
Information on age, gender, living area, personal oral habits, and monthly PM 2.5 concentration in average were collected. (aaqr.org)

[ 1 ] Joshi subsequently coined the termed oral submucous fibrosis (OSF) for the condition in 1953. (medscape.com)

The diagnosis of oral submucous fibrosis was confirmed with histopathological examination. (fortunejournals.com)
Silverman S Jr. Early diagnosis of oral cancer. (medscape.com)

Oral cancer (OC) is the fifth leading cause of cancer death and has been the fourth most common cancer in men for more than 10 consecutive years since 2003 in Taiwan (Ministry of Health and Welfare, 2018). (aaqr.org)
Protocol 1 Head and Neck Co- operative Oncology Group) SBDCECM105/13/58 (Sree Balaji Dental College and hospital Ethical Committee Meeting reference number 105/13/158) and the Department of Oral medicine and Radiology, Sree Ramachandra Dental College and hospital from June 2018 till January 2019. (researchsquare.com)

Oral submucous fibrosis: a case-control study in Chennai, South India. (medscape.com)
Oral cancer is the most common cancer in India. (citizen-news.org)
It has been reported that oral and oropharyngeal malignancies are the commonest carcinomas in males in North India and these account for about 30-40% of all cancer types in India - making it a leading cause of cancer mortality [ 3 - 5 ]. (biomedcentral.com)

The oral condition or tooth pathology that causes the development of teeth, over and above the normal 32 permanent teeth is known as hypodontia. (hxbenefit.com)

The emerging pattern suggested is the injury leading to inflammatory response and release of mediators that cause epithelial-mesenchymal transition (EMT), causing fibrosis. (opendentistryjournal.com)

Recent data suggest that oral lichenoid reactions (OLR) present a greater percentage of malignant transformation than oral lichen planus (OLP). (ecancer.org)
Oral lichen planus (OLP) is a relatively common mucocutaneous entity. (ecancer.org)

According to statistics, OSF generally progresses to oral cancer 3-16 years after the OSF diagnosis [1]. (fortunejournals.com)
And oral submucosa fibrosis is one such symptom that alarms the possibility of mouth cancer which may or may not be so. (drsharadent.com)
Silverman S Jr. Oral Cancer . (medscape.com)
Petti S, Scully C. Oral cancer: the association between nation-based alcohol-drinking profiles and oral cancer mortality. (medscape.com)
Warnakulasuriya S. Smokeless tobacco and oral cancer. (medscape.com)
Jané-Salas E, Chimenos-Küstner E, López-López J, Roselló-Llabrés X. Importance of diet in the prevention of oral cancer. (medscape.com)
Genetic etiology of oral cancer. (medscape.com)
Oral and pharyngeal cancer in Europe: Incidence, mortality and trends as presented to the Global Oral Cancer Forum. (medscape.com)
Assessment of the Risk of Oral Cancer Incidence in A High-Risk Population and Establishment of A Predictive Model for Oral Cancer Incidence Using A Population-Based Cohort in Taiwan. (medscape.com)
Rodu B, Jansson C. Smokeless tobacco and oral cancer: a review of the risks and determinants. (medscape.com)
At a workshop coordinated by the WHO Collaborating Centre for Oral Cancer and Precancer in the UK issues related to terminology, definitions and classification of oral precancer were discussed by an expert group. (nih.gov)
A case-control study of oral cancer in Changhua County, Taiwan. (ajtmh.org)
Cost of treatment of one oral cancer patient is about Rs 3.5 lacs. (citizen-news.org)
Dental caries, Oral cancer, Polymerase chain reaction. (thejcdp.com)
Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer. (thejcdp.com)
The purpose of this study is to elucidate the association between PM 2.5 and oral neoplasm, including oral potentially malignant disorder (OPMD) and oral cancer (OC), taking into account the geographical heterogeneity. (aaqr.org)
In Pakistan, where rates of smokeless tobacco use are high (and higher than cigarette use), oral cancer rates are among the highest in the world, and are significantly higher than other countries of the Region. (who.int)
Oral cancer is the second leading cancer there after breast cancer. (who.int)
Smokeless tobacco users have much higher rates of oral cancer than non-users. (who.int)
For further validation of protein expression, saliva samples collected from Oral Cancer and pre-cancer samples were analysed by ELISA (n=80). (researchsquare.com)

This comparative study was conducted in the Department of Oral and Maxillofacial Surgery, Sharif Medical and Dental College, Lahore, Pakistan during 2013-2016. (apmcfmu.com)

Oral submucous fibrosis results in marked rigidity and an eventual inability to open the mouth. (medscape.com)

once the original loosely arranged fibrous tissue is replaced by the ongoing fibrosis, the movability of the oral tissues is reduced, there is loss of flexibility and reduced opening of the mouth. (wikipedia.org)
Although soft tissue masses are not produced in the usual sense, the fibrosis of oral submucous fibrosis may be confused with generalized fibromatosis. (medscape.com)
CUR significantly improved the degree of fibrosis, levels of inflammation, and oxidative imbalances in lung tissue in animal models of PF. (frontiersin.org)

To access the efficacy of diode laser in the effective increase in mouth opening of oral submucous fibrosis induced trismus. (heraldopenaccess.us)

To evaluate dental health status and oral hygiene, the following indices were used: total number of decayed, missing and filled teeth (DMF/T) as well as surfaces (DMF/S), approximal plaque index (API), oral hygiene index (OHI), debris index (DI) and calculus index (CI). (who.int)
Do smokers bene t from dental hygiene oral prophylaxis? (who.int)
This pilot study in Nigeria evalu- ated the effect of dental oral prophylaxis on oral hygiene and periodontal indices among 13 systemically healthy smokers and 8 non-smokers. (who.int)
Smokers showed no bene t from dental oral prophylaxis in this study. (who.int)
The participants treated in the cur- nicotina palati, submucous fibrosis, vitiligo rent study were all seen in a dental hospital (leukoderma), hairy tongue, precancerous in Lagos in the year 2004. (who.int)
In a dental examination, oral vey] in the United States of America found hygiene and periodontal status scores were that smokers suffered more severe perio- recorded for all participants before they dontitis than non-smokers [ 7 ]. (who.int)
Baab and received a dental hygiene oral prophylaxis. (who.int)

B. Any one of the above stage along with oral carcinoma. (heraldopenaccess.us)
Liver fibrosis is a chronic, highly prevalent disease that may progress to cirrhosis and substantially increases the risk for development of hepatocellular carcinoma (HCC). (mdpi.com)
T. Takata, H. Ito and I. Ogawa, "Spindle Cell Squamous Carcinoma of the Oral Region. (scirp.org)

Gutkha has been strongly implicated in an increase in oral submucous fibrosis, a very malignant and debilitating condition with no cure. (who.int)

Background/purpose: Emerging evidence suggests the significance of microRNA-155 (miR-155) in fibrogenesis and oxidative stress accumulation, but its function in oral submucous fibrosis (OSF) has not been investigated. (tmu.edu.tw)

Anatomy4

Organisms1

Diseases5

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Geographicals1

Oesophageal subepithelial fibrosis: an extension of oral submucosal fibrosis. (1/66)

Oral submucous fibrosis in a 11-year-old Bangladeshi girl living in the United Kingdom. (2/66)

Interaction of collagen-related genes and susceptibility to betel quid-induced oral submucous fibrosis. (3/66)

The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern Taiwan. (4/66)

Prevalence of oral submucous fibrosis in the high natural radiation belt of Kerala, south India. (5/66)

Alterations in plasma lipid profile patterns in head and neck cancer and oral precancerous conditions. (6/66)

Oral mucosal lesions associated with use of quid. (7/66)

A novel wavelet neural network based pathological stage detection technique for an oral precancerous condition. (8/66)

Oral Submucous Fibrosis

Areca

Arecoline

Mouth Mucosa

Zinc Acetate

Submucous Plexus

Leukoplakia, Oral

Mouth Neoplasms

Dental Articulators

Hyalin

Precancerous Conditions

Glossitis

Hyaluronoglucosaminidase

Injections, Intralesional

Connective Tissue

India

Oesophageal subepithelial fibrosis: an extension of oral submucosal fibrosis. (1/66)

Oral submucous fibrosis in a 11-year-old Bangladeshi girl living in the United Kingdom. (2/66)

Interaction of collagen-related genes and susceptibility to betel quid-induced oral submucous fibrosis. (3/66)

The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern Taiwan. (4/66)

Prevalence of oral submucous fibrosis in the high natural radiation belt of Kerala, south India. (5/66)

Alterations in plasma lipid profile patterns in head and neck cancer and oral precancerous conditions. (6/66)

Oral mucosal lesions associated with use of quid. (7/66)

A novel wavelet neural network based pathological stage detection technique for an oral precancerous condition. (8/66)

Oral submucous fibrosis

Areca nut

Areca catechu

Laser surgery

Satyavati Motiram Sirsat

Smokeless tobacco keratosis

Oral cancer

Arecoline

Oral mucosa

Gutka

Leukoplakia

Betel nut chewing

Trismus

Flavin adenine dinucleotide

Tumor necrosis factor

List of skin conditions

List of diseases (O)

Precancerous condition

OSMF

Matrix metalloproteinase

Bad breath

Oral submucous fibrosis - Wikipedia

Oral Submucous Fibrosis: Background, Pathophysiology, Etiology

Oral Submucous Fibrosis: Background, Pathophysiology, Etiology

Oral submucous fibrosis--a chronic disseminated intravascular coagulation syndrome with local coagulopathy. | Gut

Role of areca nut in the causation of oral submucous fibrosis: a case-control study in Pakistan

View of UNRAVELING ABERRANT MICROENVIRONMENT IN ORAL SUBMUCOUS FIBROSIS

Oral Submucous Fibrosis Differential Diagnoses

Oral Submucous Fibrosis - Midac

Oral Submucous Fibrosis: Background, Pathophysiology, Epidemiology

Oral submucous fibrosis and malignant transformation - thespiritualmental.com

Ayurvedic Management of Oral Submucous Fibrosis - Planet Ayurveda

Treatment of Oral Submucous Fibrosis: A Case Report

Comparative study of Candida in oral submucous fibrosis and healthy individuals

A review on oral submucous fibrosis | International Journal of Current Research

My account : OSMF Mouth Opening Kit Oral Submucous Fibrosis Treatment at Home

Surgical Management of Trismus Due to Oral Submucous Fibrosis Using Diode Laser

director Archives : OSMF Mouth Opening Kit Oral Submucous Fibrosis Treatment at Home

What is Oral Submucous Fibrosis? Paan and Supari Chewing are Just as Bad as Tobacco and Gutkha

Efficacy of Ayurveda against oral submucous fibrosis - A case study | Parul University Journal of Health Sciences and...

Oral submucous fibrosis: an etiological dilemma. | J Exp Ther Oncol;12(2): 163-166, 2017 Nov. | MEDLINE | BVS Odontologia

Activation of TGF-beta Pathway by Areca Nut Constituents: A Possible Cause of Oral Submucous Fibrosis ePrints@IISc

Cancers of the Oral Mucosa Differential Diagnoses

Surgical Management of Oral Submucous Fibrosis by Comparing Two Flaps: A Comparative Study | Annals of Punjab Medical...

An improvised approach for regaining mouth opening and managing tooth wear in oral sub-mucous fibrosis<...

"Clinicobiochemical evaluation of turmeric with black pepper and Nigella sativa in management of oral submucous fibrosis-a...

Modified platysma myocutaneous flap technique for reconstruction of oral submucous fibrosis: A tehnical note - Journal of...

Depletion of miR-155 hinders the myofibroblast activities and reactive oxygen species generation in oral submucous fibrosis<...

Assessment of quality of life of patients with oral sub mucous fibrosis before and after treatment with topical curcumin |...

EVALUATION OF DNA DAMAGE BY COMET ASSAY IN PATIENTS OF ORAL SUBMUCOUS FIBROSIS (OSMF) by Rashee Mittal & Dr.Upendra Kumar Gupta

OSMF5

Squamous cell carc7

Cause oral submucous fibrosis2

Management of oral submucous2

Cavity19

Mucosa18