Osteoarthropathy, Secondary Hypertrophic
Osteoarthropathy, Primary Hypertrophic
Arthropathy, Neurogenic
Tarsal Bones
Foot Deformities, Acquired
Periostitis
Technetium Tc 99m Medronate
Joint Diseases
Immobilization
Bone Malalignment
Arthritis
MR imaging of pachydermoperiostosis. (1/31)
A case of pachydermoperiostosis who demonstrated the whole syndrome (pachyderma, periostitis, and cutis verticis gyrata) is presented, and the Magnetic Resonance Imaging (MRI) appearances of the long bone and scalp changes are demonstrated. MRI of the cruris demonstrated fluffy periosteal new bone formation that encroached on the medullary cavity as well as expansion of the diaphysis. Cranial changes included thickening of the diploe associated with diminished signal of the intradiploic fat, and thickening of the scalp with furrowing. (+info)Hypertrophic osteoarthropathy can indicate recurrence of Whipple's disease. (2/31)
We report the case of a patient with Whipple's disease (WD) who developed hypertrophic osteoarthropathy (HOA) characterized by digital clubbing, periostosis of the tubular bones, and polysynovitis. The HOA disclosed the recurrence of the patient's WD, since polymerase chain reaction (PCR) analysis clearly demonstrated the presence of Tropheryma whippelii in the synovial fluid from the patient's left knee. Initiation of appropriate antibiotic therapy resulted in complete healing of all clinical rheumatologic manifestations within 2 months and in disappearance of radiographic bone changes at 7-month followup. We suggest that HOA be included within the spectrum of rheumatologic manifestations of WD, and that an evaluation for WD should be considered in patients, especially middle-aged men, presenting with HOA even without gastrointestinal symptoms. PCR analysis may be useful in accurate diagnosis and management of early WD with unusual clinical manifestations, and may contribute to decreased morbidity and mortality. (+info)A case of hypertrophic osteoarthropathy associated with nasopharyngeal carcinoma in a child. (3/31)
Hypertrophic osteoarthropathy is characterized by clubbing of the digital tips and periosteal reaction of long bones. Most of the cases are associated with malignancy or other conditions such as congenital heart disease, liver cirrhosis, pulmonary fibrosis, biliary atresia, and gastrointestinal polyps. Hypertrophic osteoarthropathy associated with malignancy is rare in children. A few cases of hypertrophic osteoarthropathy in children with nasopharyngeal carcinoma have been reported, however, there has been no report of such case in Korea. We present a case of hypertrophic osteoarthropathy associated with nasopharyngeal carcinoma with lung metastasis in a 14-yr-old boy. In this case, hypertrophic osteoarthropathy regressed after intensive chemotherapy, but subsequently the patient died of progressive lung metastasis. (+info)Fibromatosis of the hand associated with EMO syndrome: a case report. (4/31)
BACKGROUND: EMO syndrome, defined as a triad including exophthalmus, pretibial myxedema and osteoarthropathia, is a rare condition in patients suffering from hyperthyreosis. CASE PRESENTATION: We here describe an interesting case of EMO syndrome associated with unilateral fibromatosis of the hand and an initial stage of generalized myxedema of the skin. To our knowledge a similar case has not yet been described in literature though reports about associated fibromatosis, e.g. located retroperitoneally, already exist. Familiar explanations include its initiation by autoimmune processes or aberrant T-cell cytokine stimulation leading to an overwhelming production of glycosaminoglycans. CONCLUSION: Interpreting our case in context with previous reports we conclude that associated fibromatosis induced by autoimmune processes may affect a variety of different localizations and therefore requires careful monitoring. A therapeutical attempt by using UVA1 irridation for pretibial myxedema remained without a satisfying regression. (+info)Bone abnormalities and severe arthritis in pachydermoperiostosis. (5/31)
Two patients with pachydermoperiostosis were studied in whom the predominant features at presentation were severe and disabling knee and ankle joint pain in association with distal long bone pain. Analysis of synovial fluid from the knee joints showed non-inflammatory changes. In one patient a bicortical iliac crest bone biopsy specimen, taken after labelling with demeclocycline, showed appositional rates which were increased in cortical bone but reduced in trabecular bone. This mismatching resulted in trabecular osteoporosis, which occurred in association with increased numbers of osteoclasts, findings which suggest differential functional changes affecting the two bony envelopes. (+info)Absence of an association between HLA typing in cystic fibrosis arthritis and hypertrophic osteoarthropathy. (6/31)
Fourteen patients with cystic fibrosis arthritis and eight patients with cystic fibrosis and hypertrophic osteoarthropathy were typed for HLA-A, B, C, DR, and DQ antigens and were compared with age and sex matched controls with cystic fibrosis. The diagnosis of cystic fibrosis arthritis and hypertrophic osteoarthropathy was confirmed by radiography and bone scanning. The prevalence of HLA-A, B, C, D, antigens in the cystic fibrosis group (44 patients) did not differ from that in the control group. A comparison between patients with cystic fibrosis arthritis or hypertrophic osteoarthropathy and their respective controls did not show any significant differences in HLA prevalence. It is concluded that HLA antigens may not be a factor in the susceptibility of patients with cystic fibrosis to cystic fibrosis arthritis or hypertrophic osteoarthropathy. (+info)Unusual associations of pachydermoperiostosis: a case report. (7/31)
Primary hypertrophic osteoarthropathy (HOA), or pachydermoperiostosis, is a rare benign disorder of unknown etiology. It is characterized by clubbing, periosteal reaction, and thickening of the skin. Disease usually progresses slowly, and natural arrest may occur. Reported herein is the case of a 28-year-old male patient with progressively increasing swelling of large joints of lower limbs with severe anemia. He was diagnosed as a case of pachydermoperiostosis with myelofibrosis, which is a rare association. The development of myelofibrosis makes primary HOA a disease with unfavorable outcome. (+info)Ptosis caused by pachydermoperiostosis. (8/31)
Pachydermoperiostosis is a rare inherited disorder which presents with finger clubbing, facial enlargement, and periostitis. A case is described in which surgery for ptosis was performed and the differential diagnosis of the condition is discussed. The histological and ultrastructural appearances of the eyelids show sebaceous gland hyperplasia and excessive deposition of mucin in the dermis and would suggest that pachydermoperiostosis may be an example of a cutaneous mucinosis. (+info)Secondary hyertrophic osteoarthropathy, also known as secondary musculoskeletal hypertrophy or Pierre Marie-Bamberger syndrome, is a condition characterized by the proliferation of new bone formation (osteophytes) and thickening of the bones (hyertrophy) in the joints, typically affecting the hands and feet. This condition is a reactive process that occurs as a secondary response to an underlying medical disorder, most commonly chronic hypoxia or ischemia due to conditions such as chronic obstructive pulmonary disease (COPD), cyanotic congenital heart disease, or malignancy.
The exact pathophysiology of this condition is not fully understood, but it is thought to be related to the release of growth factors and cytokines in response to the underlying medical disorder. The clinical manifestations of secondary hyertrophic osteoarthropathy include joint pain, swelling, stiffness, and limited range of motion, as well as characteristic radiographic findings such as periostitis, bone resorption, and new bone formation.
Treatment of this condition involves addressing the underlying medical disorder and providing supportive care for the musculoskeletal symptoms. This may include pain management, physical therapy, and orthopedic interventions as needed.
Primary hypertrophic osteoarthropathy (PHO), also known as pachydermoperiostosis, is a rare hereditary disorder characterized by the thickening of the skin (pachydermia) and abnormal growth of the bones (periostitis). This condition primarily affects the bones and joints, causing pain, swelling, and limited mobility.
The key features of PHO include:
1. Digits: Clubbing of the fingers and toes, with overgrowth of the bone tissue at the ends of the digits (periostitis) leading to characteristic "drumstick" appearance.
2. Skin: Thickening of the skin, particularly on the face, hands, and feet, giving a leathery or rough texture. Seborrheic dermatitis and increased sweating may also be present.
3. Bones: Periosteal new bone formation, leading to painful swelling and enlargement of the affected bones, most commonly in the long bones of the legs and arms.
4. Joints: Arthritis-like symptoms, including joint pain, stiffness, and limited mobility.
5. Other features: May include coarse hair, high arched palate, and bowing of the limbs.
The exact cause of primary hypertrophic osteoarthropathy is not fully understood but is believed to involve genetic mutations affecting the regulation of bone growth and remodeling. It is typically inherited in an autosomal dominant pattern, meaning that a child has a 50% chance of inheriting the condition if one parent is affected.
Treatment for PHO focuses on managing symptoms and improving quality of life. This may include pain relief medications, physical therapy, and surgical interventions to correct bone deformities or improve joint mobility.
Neurogenic arthropathy is a joint disease that occurs as a result of nerve damage or dysfunction. Also known as Charcot joint, this condition is characterized by joint destruction and deformity due to the loss of sensation and proprioception, which normally help protect the joint from excessive stress and injury.
Neurogenic arthropathy often affects people with diabetes, syphilis, leprosy, spinal cord injuries, or other conditions that damage nerves. The damage impairs the ability to feel pain, temperature, and position, making it difficult for individuals to notice or respond to joint injuries. Over time, this can lead to joint degeneration, fractures, dislocations, and severe deformities if left untreated.
Treatment typically involves managing the underlying nerve condition, immobilizing the affected joint with a brace or cast, and in some cases, surgical intervention to repair or replace damaged joints. Regular exercise, physical therapy, and maintaining a healthy lifestyle can also help manage symptoms and prevent further complications.
The tarsal bones are a group of seven articulating bones in the foot that make up the posterior portion of the foot, located between the talus bone of the leg and the metatarsal bones of the forefoot. They play a crucial role in supporting the body's weight and facilitating movement.
There are three categories of tarsal bones:
1. Proximal row: This includes the talus, calcaneus (heel bone), and navicular bones. The talus articulates with the tibia and fibula to form the ankle joint, while the calcaneus is the largest tarsal bone and forms the heel. The navicular bone is located between the talus and the cuneiform bones.
2. Intermediate row: This includes the cuboid bone, which is located laterally (on the outside) to the navicular bone and articulates with the calcaneus, fourth and fifth metatarsals, and the cuneiform bones.
3. Distal row: This includes three cuneiform bones - the medial, intermediate, and lateral cuneiforms - which are located between the navicular bone proximally and the first, second, and third metatarsal bones distally. The medial cuneiform is the largest of the three and articulates with the navicular bone, first metatarsal, and the intermediate cuneiform. The intermediate cuneiform articulates with the medial and lateral cuneiforms and the second metatarsal. The lateral cuneiform articulates with the intermediate cuneiform, cuboid, and fourth metatarsal.
Together, these bones form a complex network of joints that allow for movement and stability in the foot. Injuries or disorders affecting the tarsal bones can result in pain, stiffness, and difficulty walking.
Acquired foot deformities refer to structural abnormalities of the foot that develop after birth, as opposed to congenital foot deformities which are present at birth. These deformities can result from various factors such as trauma, injury, infection, neurological conditions, or complications from a medical condition like diabetes or arthritis.
Examples of acquired foot deformities include:
1. Hammertoe - A deformity where the toe bends downward at the middle joint, resembling a hammer.
2. Claw toe - A more severe form of hammertoe where the toe also curls under, forming a claw-like shape.
3. Mallet toe - A condition where the end joint of a toe is bent downward, causing it to resemble a mallet.
4. Bunions - A bony bump that forms on the inside of the foot at the big toe joint, often causing pain and difficulty wearing shoes.
5. Tailor's bunion (bunionette) - A similar condition to a bunion, but it occurs on the outside of the foot near the little toe joint.
6. Charcot foot - A severe deformity that can occur in people with diabetes or other neurological conditions, characterized by the collapse and dislocation of joints in the foot.
7. Cavus foot - A condition where the arch of the foot is excessively high, causing instability and increasing the risk of ankle injuries.
8. Flatfoot (pes planus) - A deformity where the arch of the foot collapses, leading to pain and difficulty walking.
9. Pronation deformities - Abnormal rotation or tilting of the foot, often causing instability and increasing the risk of injury.
Treatment for acquired foot deformities varies depending on the severity and underlying cause but may include orthotics, physical therapy, medication, or surgery.
Periostitis is a medical condition characterized by inflammation of the periosteum, which is the highly vascularized tissue that covers the outer surface of bones. The periosteum contains nerves and blood vessels that supply the bone and assist in bone repair and remodeling. Periostitis can occur as a result of various factors such as repetitive trauma, infection, or inflammatory diseases, leading to pain, swelling, and tenderness in the affected area. In some cases, periostitis may also lead to the formation of new bone tissue, resulting in bony outgrowths known as exostoses.
Technetium Tc 99m Medronate is a radiopharmaceutical agent used in nuclear medicine for bone scintigraphy. It is a technetium-labeled bisphosphonate compound, which accumulates in areas of increased bone turnover and metabolism. This makes it useful for detecting and evaluating various bone diseases and conditions, such as fractures, tumors, infections, and arthritis.
The "Tc 99m" refers to the radioisotope technetium-99m, which has a half-life of approximately 6 hours and emits gamma rays that can be detected by a gamma camera. The medronate component is a bisphosphonate molecule that binds to hydroxyapatite crystals in bone tissue, allowing the radiolabeled compound to accumulate in areas of active bone remodeling.
Overall, Technetium Tc 99m Medronate is an important tool in nuclear medicine for diagnosing and managing various musculoskeletal disorders.
Joint diseases is a broad term that refers to various conditions affecting the joints, including but not limited to:
1. Osteoarthritis (OA): A degenerative joint disease characterized by the breakdown of cartilage and underlying bone, leading to pain, stiffness, and potential loss of function.
2. Rheumatoid Arthritis (RA): An autoimmune disorder causing inflammation in the synovial membrane lining the joints, resulting in swelling, pain, and joint damage if left untreated.
3. Infectious Arthritis: Joint inflammation caused by bacterial, viral, or fungal infections that spread through the bloodstream or directly enter the joint space.
4. Gout: A type of arthritis resulting from the buildup of uric acid crystals in the joints, typically affecting the big toe and characterized by sudden attacks of severe pain, redness, and swelling.
5. Psoriatic Arthritis (PsA): An inflammatory joint disease associated with psoriasis, causing symptoms such as pain, stiffness, and swelling in the joints and surrounding tissues.
6. Juvenile Idiopathic Arthritis (JIA): A group of chronic arthritis conditions affecting children, characterized by joint inflammation, pain, and stiffness.
7. Ankylosing Spondylitis: A form of arthritis primarily affecting the spine, causing inflammation, pain, and potential fusion of spinal vertebrae.
8. Bursitis: Inflammation of the fluid-filled sacs (bursae) that cushion joints, leading to pain and swelling.
9. Tendinitis: Inflammation or degeneration of tendons, which connect muscles to bones, often resulting in pain and stiffness near joints.
These conditions can impact the function and mobility of affected joints, causing discomfort and limiting daily activities. Proper diagnosis and treatment are essential for managing joint diseases and preserving joint health.
I'm sorry for any confusion, but "Tibet" is not a medical term. It is a region in Asia that is currently under the political control of China, although it has a distinct cultural and historical heritage. Tibet is geographically located in the Tibetan Plateau, which is the highest region on Earth, with an average elevation of over 14,000 feet (4,267 meters) above sea level.
If you have any questions about medical terminology or health-related topics, I would be happy to try and help answer them for you!
Immobilization is a medical term that refers to the restriction of normal mobility or motion of a body part, usually to promote healing and prevent further injury. This is often achieved through the use of devices such as casts, splints, braces, slings, or traction. The goal of immobilization is to keep the injured area in a fixed position so that it can heal properly without additional damage. It may be used for various medical conditions, including fractures, dislocations, sprains, strains, and soft tissue injuries. Immobilization helps reduce pain, minimize swelling, and protect the injured site from movement that could worsen the injury or impair healing.
Bone malalignment is a term used to describe the abnormal alignment or positioning of bones in relation to each other. This condition can occur as a result of injury, deformity, surgery, or disease processes that affect the bones and joints. Bone malalignment can cause pain, stiffness, limited mobility, and an increased risk of further injury. In some cases, bone malalignment may require treatment such as bracing, physical therapy, or surgery to correct the alignment and improve function.
Arthritis is a medical condition characterized by inflammation in one or more joints, leading to symptoms such as pain, stiffness, swelling, and reduced range of motion. There are many different types of arthritis, including osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, and lupus, among others.
Osteoarthritis is the most common form of arthritis and is caused by wear and tear on the joints over time. Rheumatoid arthritis, on the other hand, is an autoimmune disorder in which the body's immune system mistakenly attacks the joint lining, causing inflammation and damage.
Arthritis can affect people of all ages, including children, although it is more common in older adults. Treatment for arthritis may include medications to manage pain and reduce inflammation, physical therapy, exercise, and in some cases, surgery.
"Bone" is the hard, dense connective tissue that makes up the skeleton of vertebrate animals. It provides support and protection for the body's internal organs, and serves as a attachment site for muscles, tendons, and ligaments. Bone is composed of cells called osteoblasts and osteoclasts, which are responsible for bone formation and resorption, respectively, and an extracellular matrix made up of collagen fibers and mineral crystals.
Bones can be classified into two main types: compact bone and spongy bone. Compact bone is dense and hard, and makes up the outer layer of all bones and the shafts of long bones. Spongy bone is less dense and contains large spaces, and makes up the ends of long bones and the interior of flat and irregular bones.
The human body has 206 bones in total. They can be further classified into five categories based on their shape: long bones, short bones, flat bones, irregular bones, and sesamoid bones.
Hypertrophic osteoarthropathy
Pachyderma
Pachydermoperiostosis
Nail clubbing
Solute carrier organic anion transporter family member 2A1
Major facilitator superfamily
Hypertrophic osteopathy
List of diseases (H)
Cutis verticis gyrata
Lung cancer
List of OMIM disorder codes
Adenocarcinoma of the lung
Cirrhosis
Neuropathic arthropathy
List of diseases (C)
Neanderthal
Dermatologic Manifestations of Pulmonary Disease: Overview, Cyanosis and Clubbing, Lung Cancer, Hypertrophic Osteoarthropathy,...
Hypertrophic osteoarthropathy, primary - Ordering
Hypertrophic osteoarthropathy - Wikipedia
OMIM - HYPERTROPHIC OSTEOARTHROPATHY, PRIMARY, AUTOSOMAL RECESSIVE, 2; PHOAR2 - OMIM - NCBI
Clinical and research tests for C4551679 - Genetic Testing Registry (GTR) - NCBI
Dermatologic Manifestations of Pulmonary Disease: Overview, Cyanosis and Clubbing, Lung Cancer, Hypertrophic Osteoarthropathy,...
Journal of Cancer Research and Experimental Oncology - articles
Geometry.Net - Health Conditions: Crow-fukase Syndrome
Ahead of Print - Indian Journal of Dermatology, Venereology and Leprology
Ankle arthritis - an important signpost in rheumatologic practice
Giant cell carcinoma of the lung with hypertrophic pulmonary osteoarthropathy as a paraneoplastic syndrome: a case report |...
Pachydermoperiostosis syndrome
urofacial syndrome - Ontology Browser - Rat Genome Database
DeCS
Volume 3(2) 1997 (28)
Browse In Hands - enlargement | EDM Case Reports
Evaluation of the Pulmonary Patient - Pulmonary Disorders - MSD Manual Professional Edition
Joint Diseases, Health Challenges, and Disorders < Musculoskeletal Health Challenges << Diseases <<< Sick Care Systems ...
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Rush Limbaugh's Advanced Lung Cancer | MedPage Today
Cep135 Mouse Gene Details | centrosomal protein 135 | International Mouse Phenotyping Consortium
"Clubbing"[Clinical Features] OR 57692[uid] - MedGen -...
Connexion
Pesquisa | Prevenção e Controle de Câncer
Joint Deformities, Acquired | Harvard Catalyst Profiles | Harvard Catalyst
Researchers interested in Pseudoxanthoma Elasticum | Directory of Faculty Research Interests
Nail clubbing in laxative abuse: case report and review of the literature | Journal of Eating Disorders | Full Text
Increased risk of malignancy in patients with Takayasu's arteritis: a population-based cohort study in Korea | Scientific...
Diagnosis and Staging of Lung Cancer | Pearson's General Thoracic
Pulmonary8
- Hypertrophic pulmonary osteoarthropathy (HPOA) (Pierre Marie-Bamberger syndrome): two cases presenting as acute inflammatory arthritis. (wikipedia.org)
- Hypertrophic pulmonary osteoarthropathy is a rare syndrome characterized by a triad that includes periostitis, digital clubbing, and painful arthropathy of the large joints, especially large joints in the lower limbs with lung cancer. (biomedcentral.com)
- Herein we describe a case of a giant cell carcinoma of the lung with hypertrophic pulmonary osteoarthropathy as a paraneoplastic syndrome. (biomedcentral.com)
- The clinical stage was c-T2bN0M0 with paraneoplastic syndrome as a hypertrophic pulmonary osteoarthropathy. (biomedcentral.com)
- Hypertrophic pulmonary osteoarthritis may occur as a secondary manifestation of lung malignancies. (biomedcentral.com)
- Hypertrophic pulmonary osteoarthropathy (HPOA) is a paraneoplastic syndrome that occurs in patients with lung cancer. (biomedcentral.com)
- [ 1 ] However, the highly rugose nature of his facial and scalp skin, and the presence of finger clubbing suggested the alternative diagnosis of pachydermoperiostosis, also known as hypertrophic pulmonary osteoarthropathy (primary hypertrophic osteoarthropathy autosomal recessive 2, PHOAR2). (medscape.com)
- [ 12 ] Rare cases of primary pulmonary or pleural DSRCT have subsequently been identified. (medscape.com)
PACHYDERMOPERIOSTOSIS2
- Pachydermoperiostosis (PDP), also known as Touraine-Solente-Golé syndrome and primary hypertrophic osteoarthropathy, is a very rare genodermatosis marked by facial skin thickening, furrowing and oiliness (pachydermia), digital clubbing, and periostosis. (logicalimages.com)
- Secondary hypertrophic osteoarthropathy (SHO), also called secondary pachydermoperiostosis or Pierre-Marie Bamberger syndrome, is the main differential diagnosis. (logicalimages.com)
Osteitis1
- Periarticular hind foot swelling can be confused with ankle arthritis, exemplified by Lofgren's syndrome and hypertrophic osteoarthropathy where swelling is due to subcutaneous oedema and osteitis respectively, and the ankle joint is rarely involved. (nih.gov)
Syndrome2
- B cells, related to, and often associated with, primary nodal plasmacytoma and osteosclerotic myeloma (socalled POEMS, Takatsuki s or crow-fukase s syndrome). (geometry.net)
- It is also part of the syndrome of primary or secondary hypertrophic osteoarthropathy (HOA). (biomedcentral.com)
Lung5
- The condition may occur alone (primary), or it may be secondary to diseases like lung cancer. (wikipedia.org)
- citation needed] Hypertrophic osteoarthropathy is one of many distant effect disorders due to cancer, with lung cancer being the most common cause but also occurring with ovarian or adrenal malignancies. (wikipedia.org)
- Treatment of lung cancer or other causes of hypertrophic osteoarthropathy results in regression of symptoms for some patients. (wikipedia.org)
- The current TNM staging system is used for non-small cell lung cancer (NSCLC) and more recently neuroendocrine tumors including small cell lung cancer (SCLC), and provides a framework for the assessment of prognosis and the assignment of therapy for patients with a new diagnosis of lung cancer using the histopathologic evaluation of the primary tumor (T), lymph nodes (N), and metastatic disease (M). (sts.org)
- [ 5 ] An earlier report, in 1956, by Babolini and Blasi, described the same clinicopathological entity using the nomenclature, "The pleural form of primary cancer of the lung. (medscape.com)
Familial1
- Familial occurrence of primary hypertrophic osteoarthropathy. (medscitechnol.com)
Gene1
- Homozygous mutations in the 15-hydroxyprostaglandin dehydrogenase gene in patients with primary hypertrophic osteoarthropathy. (univ-paris5.fr)
Disorders1
- Clubbing may be hereditary (ie, primary hypertrophic osteoarthropathy , which is discussed in the next section), but, more often, it is acquired and is associated with a number of infectious, inflammatory, neoplastic, and vascular disorders. (medscape.com)
Clubbing1
- Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. (wikipedia.org)
Painful1
- The associated arthropathy of the large limb joints tends to be more severe and painful than in the primary form. (logicalimages.com)
Thoracic1
- Symptoms and signs may result from the location of the primary local invasion or compression of adjacent thoracic structures, distant metastases, or paraneoplastic phenomena. (medpagetoday.com)
Neoplasms1
- And scrotal enlargement, chapter general considerations primary epithelial neoplasms of the already damaged organs. (albionfoundation.org)
Patients1
- 摘要: The overall diagnostic capabilities and utility of frequency-doubling technology (FDT) in patients with primary glaucoma, which was diagnosed by standard automated perimetry (SAP) and/or optic disc appearance as the gold standard, were assessed. (engineering.org.cn)
Site1
- This category will also be used in primary coding to classify bacterial infections of unspecified nature or site. (cdc.gov)
Joint1
- Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. (wakehealth.edu)
Metastatic1
- The most common category of nonmesotheliomatous cancer to involve the pleura is represented by extrapleural primary malignancies that secondarily involve the pleura via metastatic spread. (medscape.com)
Result1
- Hypogonadism , a decrease in male sex hormones may manifest as impotence, infertility, loss of sexual drive, and testicular atrophy , and can result from primary gonadal injury or suppression of hypothalamic/pituitary function. (alchetron.com)
Pachydermoperiostosis4
- There are two types of PHO: pachydermoperiostosis and cranio-osteoarthropathy. (nih.gov)
- HOA can be a primary entity, known as pachydermoperiostosis, or can be secondary to extraskeletal conditions, with different prognoses and management implications for each. (nih.gov)
- Causes of idiopathic or primary clubbing include pachydermoperiostosis, familial clubbing, and hypertrophic osteoarthropathy. (medscape.com)
- Pachydermoperiostosis (PDP) is a form of primary hypertrophic osteoarthropathy (see this term) a rare hereditary disorder and is characterized by digital clubbing pachydermia and subperiosteal new bone formation associated with pain polyarthritis cutis verticis gyrata seborrhea and hyperhidrosis. (globalgenes.org)
Hereditary6
- Clubbing may be hereditary (ie, primary hypertrophic osteoarthropathy , which is discussed in the next section), but, more often, it is acquired and is associated with a number of infectious, inflammatory, neoplastic, and vascular disorders. (medscape.com)
- Digital clubbing is classified into primary (ie, idiopathic, hereditary) and secondary forms. (medscape.com)
- Primary hypertrophic osteoarthropathy (PHO), a rare hereditary disorder with digital clubbing, subperiosteal new bone formation, and arthropathy, has been linked mutations in the 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) encoding gene HPGD , which causes PHO. (medscape.com)
- HOA can be primary (hereditary or idiopathic) or secondary. (medscape.com)
- HOA is classified either as primary (hereditary or idiopathic) or secondary. (medscape.com)
- A form of primary hypertrophic osteoarthropathy, a rare hereditary disorder with characteristics of digital clubbing, pachydermia and subperiosteal new bone formation associated with pain, polyarthritis, cutis verticis gyrata, seborrhea and hyperhidrosis. (cdc.gov)
Pulmonary hypertrophic osteoarthropathy9
- 2. Pulmonary hypertrophic osteoarthropathy in a patient with nonsmall cell lung cancer: Diagnosis with FDG PET/CT. (nih.gov)
- 13. [A case of pulmonary pleomorphic carcinoma accompanied by pulmonary hypertrophic osteoarthropathy]. (nih.gov)
- 15. Pulmonary hypertrophic osteoarthropathy and its resolution. (nih.gov)
- With the exclusion of infection, loosening, instability, and crystalline synovitis, we made the presumptive diagnosis of pulmonary hypertrophic osteoarthropathy of the distal parts of both femora. (jbjs.org)
- An unusual cause of late pain and effusion after total knee arthroplasty: pulmonary hypertrophic osteoarthropathy. (jbjs.org)
- To our knowledge, this is the first report of pulmonary hypertrophic osteoarthropathy occurring in a patient who had had a total knee arthroplasty. (jbjs.org)
- Primary pulmonary hypertrophic osteoarthropathy presents in young adults with digital clubbing, periosteal reaction of the long bones, and hypertrophic skin changes. (jbjs.org)
- A review of the literature identified four reports of pulmonary hypertrophic osteoarthropathy associated with small-cell carcinoma of the lung. (jbjs.org)
- The symptoms of pulmonary hypertrophic osteoarthropathy can include debilitating joint pain, effusions, and clubbing of the fingers. (jbjs.org)
Cranioosteoarthropathy1
- Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. (nih.gov)
Periostitis4
- Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. (wikipedia.org)
- Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by clubbing of the digits, periostitis of the long (tubular) bones, and arthritis. (medscape.com)
- The clinical triad of digital clubbing, arthralgias, and ossifying periostitis that characterizes hypertrophic osteoarthropathy (HOA) has been recognized since the late 1800s and was previously known as hypertrophic pulmonary osteoarthropathy (HPOA). (medscape.com)
- It is challenging to identify incomplete primary HOA, which can be misdiagnosed as other hypertrophic periostitis diseases. (akjournals.com)
Paraneoplastic syndrome1
- NSCLC is diagnosed because of symptoms related to the primary tumor or regional or distant metastases, as an incidental finding on chest radiograph, or rarely because of a paraneoplastic syndrome such as hypercalcemia or hypertrophic pulmonary osteoarthropathy. (elsevierpure.com)
HPOA1
- Hypertrophic pulmonary osteoarthropathy (HPOA) (Pierre Marie-Bamberger syndrome): two cases presenting as acute inflammatory arthritis. (wikipedia.org)
Periosteal3
- Periosteal reaction Hypertrophic osteopathy Armstrong DJ, McCausland EM, Wright GD (February 2007). (wikipedia.org)
- Hypertrophic osteoarthropathy (HOA) is a medical condition characterized by abnormal proliferation of skin and periosteal tissues involving the extremities and characterized by three clinical features: digital clubbing (also termed Hippocratic fingers), periostosis of tubular bones, and synovial effusions. (nih.gov)
- Hypertrophic osteoarthropathy (HOA) is characterized by clubbed fingers and periosteal new bone formation. (ogu.edu.tr)
Distal1
- Two types of bone changes can be found in the distal phalanges, hypertrophic and osteolytic. (medscape.com)
Bone1
- 16. [Analgesic effect of Pamidronate on bone pain in patient with hypertrophic pulmonary osteoarthropathy]. (nih.gov)
Descriptor1
- Osteoarthropathy, Primary Hypertrophic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sdsu.edu)
Secondary forms1
- This disorder exists in both primary and secondary forms. (jbjs.org)
Clinical2
- His primary clinical focus includes the management of Non-Hodgkin's and Hodgkin's lymphomas. (moffitt.org)
- Dr. Saeed's primary research expertise focuses on early phase clinical trials using novel chemotherapy combinations. (moffitt.org)
Diagnosis1
- In some cases, the diagnosis of HOA as primary can be challenged with the development of a disease that is known to be associated with secondary HOA. (medscape.com)
Congenital1
- Primary hypertrophic osteoarthropathy (PHO) is a genetically and clinically heterogeneous inherited disorder characterized by digital clubbing and osteoarthropathy, with variable features of pachydermia, delayed closure of the fontanels, and congenital heart disease. (nih.gov)
Cancers1
- Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response. (insilicase.com)
Therapy1
- Therapy for HOA consists of treatment of the primary cause and symptomatic treatment. (medscape.com)
Rare1
- Primary hypertrophic osteoarthropathy (HOA) is a rare condition with no identifiable cause, accounting for 3%-5% of all HOA cases. (akjournals.com)
Adenocarcinoma1
- 14. Postchemotherapeutic reversibility of hypertrophic osteoarthropathy in a patient with bronchogenic adenocarcinoma. (nih.gov)
20011
- Lilip( Sunnyvale, CA) Assignee(s): Paracor Surgical, Inc. Sunnyvale, CA) Patent Number: 6,595,912 heart left: September 14, 2001 cell: A primary output for encompassing congestive mechanism lysis improves produced. (siriuspixels.com)
Case2
- We present a case of incomplete primary PHOA at Hanoi Medical University Hospital in Vietnam. (akjournals.com)
- Our case report and literature review aim to improve specialists' understanding of incomplete primary HOA and reduce the frequency of missed diagnoses. (akjournals.com)
Publications2
- This graph shows the total number of publications written about "Osteoarthropathy, Primary Hypertrophic" by people in this website by year, and whether "Osteoarthropathy, Primary Hypertrophic" was a major or minor topic of these publications. (sdsu.edu)
- Below are the most recent publications written about "Osteoarthropathy, Primary Hypertrophic" by people in Profiles. (sdsu.edu)
Early1
- 10. Hypertrophic pulmonary osteoarthropathy in nasopharyngeal carcinoma: an early sign of pulmonary metastasis. (nih.gov)