A form of panniculitis characterized by recurrent episodes of fever accompanied by the eruption of single or multiple erythematous subcutaneous nodules on the lower extremities. They normally resolve, but tend to leave depressions in the skin. The condition is most often seen in women, alone or in association with other disorders.
INFLAMMATION of the underlying layer of ADIPOSE TISSUE (panniculus) of the PERITONEUM, usually of the MESENTERY or the OMENTUM. There are several forms with various names and are usually characterized by infiltration of LYMPHOCYTES and NEUTROPHILS, fat NECROSIS, and FIBROSIS.
General term for the abnormal appearance of histiocytes in the blood. Based on the pathological features of the cells involved rather than on clinical findings, the histiocytic diseases are subdivided into three groups: HISTIOCYTOSIS, LANGERHANS CELL; HISTIOCYTOSIS, NON-LANGERHANS-CELL; and HISTIOCYTIC DISORDERS, MALIGNANT.
An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions.
An erythematous eruption commonly associated with drug reactions or infection and characterized by inflammatory nodules that are usually tender, multiple, and bilateral. These nodules are located predominantly on the shins with less common occurrence on the thighs and forearms. They undergo characteristic color changes ending in temporary bruise-like areas. This condition usually subsides in 3-6 weeks without scarring or atrophy.
A type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. It is seen most commonly in adolescent and menopausal women, is initiated or exacerbated by cold weather, and typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves. The nodules may progress to form indurations, ulcerations, and scars.
Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.
A general term indicating inflammation of the BRAIN and SPINAL CORD, often used to indicate an infectious process, but also applicable to a variety of autoimmune and toxic-metabolic conditions. There is significant overlap regarding the usage of this term and ENCEPHALITIS in the literature.
'Zoo animals' are various species of captive wild animals, housed and displayed in a facility for the purpose of public education, conservation, research, and recreation.
Acute or chronic INFLAMMATION of the PANCREAS due to excessive ALCOHOL DRINKING. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.
Macrophages found in the TISSUES, as opposed to those found in the blood (MONOCYTES) or serous cavities (SEROUS MEMBRANE).
A type of lupus erythematosus characterized by deep dermal or subcutaneous nodules, most often on the head, face, or upper arms. It is generally chronic and occurs most often in women between the ages of 20 and 45.
Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
The engulfment and degradation of cells by other cells.
Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.
FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cirrhosis involves the destruction of small intra-hepatic bile ducts and bile secretion. Secondary biliary cirrhosis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.
Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.
Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of causes.
Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.
Infections with nematodes of the genus GNATHOSTOMA, superfamily THELAZIOIDEA. Gnathostomiasis is a food-borne zoonosis caused by eating undercooked or raw fish or meat.
General term for inflammation of adipose tissue, usually of the skin, characterized by reddened subcutaneous nodules.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
'Skin diseases' is a broad term for various conditions affecting the skin, including inflammatory disorders, infections, benign and malignant tumors, congenital abnormalities, and degenerative diseases, which can cause symptoms such as rashes, discoloration, eruptions, lesions, itching, or pain.
A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. MYCOSIS FUNGOIDES; SEZARY SYNDROME; LYMPHOMATOID PAPULOSIS; and PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA are the best characterized of these disorders.
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
A severe form of acute INFLAMMATION of the PANCREAS characterized by one or more areas of NECROSIS in the pancreas with varying degree of involvement of the surrounding tissues or organ systems. Massive pancreatic necrosis may lead to DIABETES MELLITUS, and malabsorption.
A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
A spontaneous diminution or abatement of a disease over time, without formal treatment.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.

Cytophagic histiocytic panniculitis improved by combined CHOP and cyclosporin A treatment. (1/24)

In a 31-year-old Japanese man with cytophagic histiocytic panniculitis (CHP) remission was achieved by a combination of combined chemotherapy CHOP and cyclosporin A treatment. He was admitted to our hospital in January 1994 with recurrent high fever of 40.2 degrees C and tender and violaceous subcutaneous nodules on his trunk, arms and legs. He developed pancytopenia, hemorrhagic diathesis, liver dysfunction. Histological examination of the biopsied subcutaneous nodule revealed a lobular panniculitis with fat necrosis and a massive infiltration of histiocytes phagocytosing nuclear debris. He was treated initially with 40 mg/day prednisolone. However, following a reduction in prednisolone dosage, his symptoms reappeared. CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) therapy was then initiated. Three courses of CHOP treatment alleviated his symptoms and cyclosporin A was used to maintain his condition for 15 months. His medication was then discontinued and he has been in complete remission for 10 months. Combined treatment of cyclosporin A and CHOP combined chemotherapy was shown to be effective for this patient with severe CHP.  (+info)

Successful treatment of a patient with febrile, lobular panniculitis (Weber-Christian disease) with oral cyclosporin A: implications for pathogenesis and therapy. (2/24)

We report a 15-year-old Japanese girl with severe systemic Weber-Christian disease (WCD) who presented with acute onset of high fever associated with tender subcutaneous nodules. Laboratory tests showed an elevated serum concentration of lactate dehydrogenase (LDH), leukopenia, and coagulation abnormalities. The anti-nuclear and anti-DNA antibodies were negative, and the serum pancreatic enzymes and alpha 1-antitrypsin levels were normal. Pulse steroid therapy was not effective, and eventually cerebellar hemorrhage occurred. After initiation of oral cyclosporin A (CyA) therapy, fever came down and her clinical condition improved markedly. Extremely high serum concentrations of interferon-gamma (IFN-gamma) and soluble interleukin-2 receptor (sIL-2R) in this patient returned to normal with CyA therapy. These findings suggest that T-cell immune responses are involved in the pathogenesis of WCD, and that CyA is effective against the disease via suppression of T-cell reactions.  (+info)

Weber-Christian disease presenting with proptosis: a case report. (3/24)

Weber-Christian disease (WCD) is a rare inflammatory disease of adipose tissue, which is characterized by painful cutaneous nodules and constitutional symptoms. Although any area of the body containing fat can be affected by WCD, the involvement of retrobulbar fat is uncommon and proptosis is a rare presenting manifestation. We report a case who presented with proptosis of the right eye which is accompanied by painful subcutaneous nodules, high fever and myalgia. Biopsies of retrobulbar tissue and suprapubic nodule showed lobular panniculitis with mixed cellular infiltration, mainly composed of histiocytes and lymphocytes. He responded well to high-dose glucocorticoid.  (+info)

Clinicopathologic evaluation of nodular cutaneous lesions of Behcet syndrome. (4/24)

Among the cutaneous manifestations, nodular lesions are rather common in Behcet syndrome. The histologic nature of these lesions has been a matter of controversy. To establish their distinguishing features, biopsy specimens from nodular lesions of 24 patients with Behcet syndrome, 25 with nodular vasculitis (NV), and 20 with erythema nodosum (EN) were compared. Statistical analysis revealed insignificant differences between most of the histologic features of Behced syndrome and NV. However, neutrophil-predominating infiltrate in the subcutis was more common in Behcet syndrome, while necrosis and granuloma formation were encountered more frequently in NV. The differences between Behced syndrome and EN were more significant. Septal panniculitis, lymphocyte-predominating infiltrate, absence of many vascular changes as well as vasculitis, and necrosis were features in favor of EN. Nodular lesions of Behcet syndrome are mainly neutrophilic vascular reactions with histologic features similar to NV but significantly differing from EN associated with other systemic diseases.  (+info)

SYSTEMIC WEBER-CHRISTIAN DISEASE. (5/24)

A patient suffering from Weber-Christian panniculitis was found at necropsy to have similar lesions in the visceral adipose tissue. When the lesions occur internally, diagnosis during life is complicated by the difficulty of examining visceral adipose tissue and the disease may often go unrecognized, but patients suffering from Weber-Christian panniculitis should be investigated bearing in mind the possibility of internal lesions. Only 11 cases confirmed by necropsy appear to have been reported hitherto. The aetiology remains obscure. It is suggested that the name ;systemic Weber-Christian disease' be applied when the lesions occur in adipose tissue other than the panniculus adiposus and that the term ;Weber-Christian panniculitis' be used when the lesions are confined to the subcutaneous adipose tissue.  (+info)

Small vessel vasculitis and relapsing panniculitis in tumour necrosis factor receptor associated periodic syndrome (TRAPS). (6/24)

CASE REPORTS: A 66 year old female patient had relapsing fever and non-suppurative panniculitis suggestive of enigmatic "Weber-Christian disease" (WCD). Antineutrophil cytoplasmic antibodies with specificity for human leucocyte elastase (HLE-ANCA) were detected. A biopsy showed small vessel vasculitis and panniculitis. A 53 year old man had recurrent episodes of abdominal pain, erythematous rash, and myalgia. Fever attacks had stopped a few years ago. A biopsy showed panniculitis and fasciitis. In both patients mutations (R92Q, T50M) of the tumour necrosis factor receptor super family (TNFRSF) 1A gene were disclosed. Mutations of the TNFRSF 1A gene are the cause of tumour necrosis factor receptor associated periodic syndrome (TRAPS). Both patients responded favourably to treatment with the human soluble p75 TNF alpha receptor fusion protein etanercept (2 x 25 mg subcutaneously/week). DISCUSSION: Small vessel vasculitis and panniculitis have not been reported in TRAPS so far. The cases underline the importance of TNF alpha regulation in inflammatory processes including vasculitis. Genetically determined causes of fever may account for some cases of WCD.  (+info)

Pancreatic panniculitis associated with allograft pancreatitis and rejection in a simultaneous pancreas-kidney transplant recipient. (7/24)

Pancreatic panniculitis is an uncommon condition that can occur in association with pancreatic disease. We present a case of pancreatic panniculitis in a female pancreas-kidney transplant recipient 5 months post-transplant. The patient was on standard immunosuppressive medications and had acute rejection of her renal allograft. The diagnosis of allograft pancreatitis and rejection presenting with pancreatic panniculitis was supported clinically, histopathologically and by laboratory and imaging data. This is the fourth case of pancreatic panniculitis occurring in a transplant recipient and the first in a simultaneous pancreas-kidney transplant recipient. It is also the first case associated with allograft rejection. Clinicians should be aware that pancreatic panniculitis may be a manifestation of underlying allograft pancreatic disease.  (+info)

A patient with Pfeifer-Weber-Christian disease--successful therapy with cyclosporin A: case report. (8/24)

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Nodular nonsuppurative panniculitis is a rare inflammatory condition that affects the subcutaneous fat tissue. The term "nonsuppurative" indicates that it does not involve pus formation or suppuration, unlike some other forms of panniculitis.

In nodular nonsuppurative panniculitis, multiple, firm, and occasionally tender nodules develop in the subcutaneous fat layer, usually on the lower extremities but can also occur on the abdomen, arms, and trunk. These nodules may vary in size from a few millimeters to several centimeters.

The etiology of nodular nonsuppurative panniculitis is not well understood, although it has been associated with various conditions such as autoimmune disorders (e.g., lupus erythematosus, rheumatoid arthritis), infections (e.g., hepatitis C, HIV), medications (e.g., bromocriptine, interferon), and malignancies (e.g., lymphoma).

Histologically, the condition is characterized by a lobular inflammatory infiltrate predominantly composed of lymphocytes, histiocytes, and occasionally plasma cells, with sparing of septa. The overlying skin may appear normal or show mild changes such as erythema or induration.

Treatment for nodular nonsuppurative panniculitis depends on the underlying cause. If an associated condition or medication is identified, addressing it may lead to resolution of the panniculitis. In cases where no specific cause is found, various treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, immunosuppressive agents, and antimalarials have been used with varying success rates.

Peritoneal panniculitis is a rare inflammatory condition that affects the fatty tissue (panniculus) in the peritoneum, which is the thin membrane that lines the inside of the abdominal cavity and covers the organs within it. The condition is characterized by the accumulation of inflammatory cells in the fatty tissue, leading to nodular or diffuse enlargement and subsequent necrosis (death) of the adipose tissue.

Peritoneal panniculitis can occur as a primary disorder or secondary to other medical conditions such as malignancies, infections, autoimmune diseases, or reactions to medications. The exact cause of primary peritoneal panniculitis remains unclear. Symptoms may include abdominal pain, bloating, fever, weight loss, and elevated white blood cell count. Diagnosis typically involves imaging studies (such as CT or MRI scans) and confirmation through biopsy of the affected tissue. Treatment depends on the underlying cause but often includes corticosteroids and other immunosuppressive medications to manage the inflammation.

Histiocytosis is a term used to describe a group of rare disorders characterized by an abnormal increase in the number of histiocytes, which are a type of white blood cell that helps fight infection and helps in healing processes. These disorders can affect various organs and tissues in the body, leading to different symptoms and severity.

There are several types of histiocytosis, including Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), and hemophagocytic lymphohistiocytosis (HLH). Each type has its own specific features and diagnostic criteria.

For example, LCH is characterized by the abnormal accumulation of Langerhans cells, a type of histiocyte found in the skin and mucous membranes. These cells can form tumors or lesions in various organs, such as the bones, lungs, liver, and skin.

HLH, on the other hand, is a life-threatening condition that occurs when there is an overactive immune response leading to excessive activation of histiocytes and other immune cells. This can result in fever, enlargement of the liver and spleen, and decreased blood cell counts.

The exact cause of histiocytosis is not fully understood, but it is believed to involve genetic mutations that lead to uncontrolled proliferation and accumulation of histiocytes. Treatment for histiocytosis depends on the type and severity of the disorder and may include chemotherapy, radiation therapy, immunosuppressive drugs, or stem cell transplantation.

Meningoencephalitis is a medical term that refers to an inflammation of both the brain (encephalitis) and the membranes covering the brain and spinal cord (meninges), known as the meninges. It is often caused by an infection, such as bacterial or viral infections, that spreads to the meninges and brain. In some cases, it can also be caused by other factors like autoimmune disorders or certain medications.

The symptoms of meningoencephalitis may include fever, headache, stiff neck, confusion, seizures, and changes in mental status. If left untreated, this condition can lead to serious complications, such as brain damage, hearing loss, learning disabilities, or even death. Treatment typically involves antibiotics for bacterial infections or antiviral medications for viral infections, along with supportive care to manage symptoms and prevent complications.

Erythema nodosum is a type of inflammation that occurs in the fatty layer of the skin, causing painful, red or purple bumps (nodules) to form. It is a type of panniculitis, which refers to any condition that causes inflammation of the fatty layer of tissue beneath the skin.

Erythema nodosum is often associated with a variety of underlying conditions, such as infections (e.g., streptococcus, tuberculosis), medications (e.g., sulfa drugs, oral contraceptives), inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis), and pregnancy.

The bumps associated with erythema nodosum typically appear on the shins, ankles, knees, or other areas of the legs, although they can also occur on the arms, hands, or face. The bumps may be tender to the touch, warm, and swollen, and they may cause pain or discomfort when walking or standing for prolonged periods.

In most cases, erythema nodosum resolves on its own within a few weeks to several months, although symptoms can be managed with medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. Treating the underlying condition is also important for resolving erythema nodosum and preventing recurrences.

Erythema induratum is a skin condition that is characterized by inflammation and hardening of the skin, usually occurring on the calves of the legs. It is also known as Bazin's disease. The condition typically affects young women and is thought to be related to tuberculosis infection.

The symptoms of erythema induratum include red, painful, and hard nodules or plaques on the skin that may ulcerate and form crusts. These lesions can be tender to the touch and may cause scarring. The condition often affects both legs and can be accompanied by fever, fatigue, and other systemic symptoms of tuberculosis.

The diagnosis of erythema induratum is typically made based on the clinical presentation of the skin lesions and confirmed with laboratory tests such as a biopsy or culture to detect tuberculosis infection. Treatment usually involves antibiotics to treat the underlying tuberculosis infection, as well as anti-inflammatory medications to manage the skin symptoms. In some cases, surgical removal of the lesions may be necessary.

Protozoan infections in animals refer to diseases caused by the invasion and colonization of one or more protozoan species in an animal host's body. Protozoa are single-celled eukaryotic organisms that can exist as parasites and can be transmitted through various modes, such as direct contact with infected animals, contaminated food or water, vectors like insects, and fecal-oral route.

Examples of protozoan infections in animals include:

1. Coccidiosis: It is a common intestinal disease caused by several species of the genus Eimeria that affects various animals, including poultry, cattle, sheep, goats, and pets like cats and dogs. The parasites infect the epithelial cells lining the intestines, causing diarrhea, weight loss, dehydration, and sometimes death in severe cases.
2. Toxoplasmosis: It is a zoonotic disease caused by the protozoan Toxoplasma gondii that can infect various warm-blooded animals, including humans, livestock, and pets like cats. The parasite forms cysts in various tissues, such as muscles, brain, and eyes, causing mild to severe symptoms depending on the host's immune status.
3. Babesiosis: It is a tick-borne disease caused by several species of Babesia protozoa that affect various animals, including cattle, horses, dogs, and humans. The parasites infect red blood cells, causing anemia, fever, weakness, and sometimes death in severe cases.
4. Leishmaniasis: It is a vector-borne disease caused by several species of Leishmania protozoa that affect various animals, including dogs, cats, and humans. The parasites are transmitted through the bite of infected sandflies and can cause skin lesions, anemia, fever, weight loss, and sometimes death in severe cases.
5. Cryptosporidiosis: It is a waterborne disease caused by the protozoan Cryptosporidium parvum that affects various animals, including humans, livestock, and pets like dogs and cats. The parasites infect the epithelial cells lining the intestines, causing diarrhea, abdominal pain, and dehydration.

Prevention and control of these diseases rely on various measures, such as vaccination, chemoprophylaxis, vector control, and environmental management. Public awareness and education are also essential to prevent the transmission and spread of these diseases.

Encephalomyelitis is a medical term that refers to inflammation of both the brain (encephalitis) and spinal cord (myelitis). This condition can be caused by various infectious agents, such as viruses, bacteria, fungi, or parasites, or it can be due to an autoimmune response where the body's own immune system attacks the nervous tissue.

The symptoms of encephalomyelitis can vary widely depending on the extent and location of the inflammation, but they may include fever, headache, stiff neck, seizures, muscle weakness, sensory changes, and difficulty with coordination or walking. In severe cases, encephalomyelitis can lead to permanent neurological damage or even death.

Treatment for encephalomyelitis typically involves addressing the underlying cause, such as administering antiviral medications for viral infections or immunosuppressive drugs for autoimmune reactions. Supportive care, such as pain management, physical therapy, and rehabilitation, may also be necessary to help manage symptoms and promote recovery.

"Animals, Zoo" is not a medical term. However, it generally refers to a collection of various species of wild animals kept in enclosures or exhibits for the public to view and learn about. These animals are usually obtained from different parts of the world and live in environments that attempt to simulate their natural habitats. Zoos play an essential role in conservation efforts, education, and research. They provide a unique opportunity for people to connect with wildlife and understand the importance of preserving and protecting endangered species and their ecosystems.

Alcoholic pancreatitis is a specific type of pancreatitis, which is inflammation of the pancreas. This condition is caused by excessive and prolonged consumption of alcohol. The exact mechanism by which alcohol induces pancreatitis is not fully understood, but it is believed that alcohol causes damage to the cells of the pancreas, leading to inflammation. This can result in abdominal pain, nausea, vomiting, fever, and increased heart rate. Chronic alcoholic pancreatitis can also lead to serious complications such as diabetes, malnutrition, and pancreatic cancer. Treatment typically involves supportive care, such as hydration, pain management, and nutritional support, along with abstinence from alcohol. In severe cases, surgery may be necessary to remove damaged tissue or to relieve blockages in the pancreas.

Histiocytes are a type of immune cell that are part of the mononuclear phagocyte system. They originate from monocytes, which are derived from hematopoietic stem cells in the bone marrow. Histiocytes play an important role in the immune system by engulfing and destroying foreign substances, such as bacteria and viruses, as well as removing dead cells and other debris from the body. They can be found in various tissues throughout the body, including the skin, lymph nodes, spleen, and liver.

Histiocytes include several different types of cells, such as macrophages, dendritic cells, and Langerhans cells. These cells have different functions but all play a role in the immune response. For example, macrophages are involved in inflammation and tissue repair, while dendritic cells are important for presenting antigens to T cells and initiating an immune response.

Abnormal accumulations or dysfunction of histiocytes can lead to various diseases, such as histiocytosis, which is a group of disorders characterized by the abnormal proliferation and accumulation of histiocytes in various tissues.

Lupus erythematosus panniculitis (LEP), also known as lupus profundus, is a type of cutaneous lupus erythematosus (CLE) that affects the fatty layer under the skin (subcutaneous tissue). It is characterized by deep inflammation of the fatty tissue, leading to nodular or indurated (hardened) plaques and subcutaneous ulcerations. The lesions are typically tender and can be painful. LEP most commonly affects the face, trunk, and proximal extremities.

LEP is associated with systemic lupus erythematosus (SLE), but it can also occur in isolation without evidence of systemic involvement. It is estimated that approximately 1-10% of patients with SLE develop LEP. The exact pathogenesis of LEP remains unclear, but it is thought to involve an autoimmune response directed against the fatty tissue.

Histologically, LEP is characterized by lobular panniculitis with lymphocytic infiltration and fat necrosis. Direct immunofluorescence may show deposition of immune complexes along the blood vessels in the affected area.

Treatment of LEP can be challenging, and often requires a multidisciplinary approach involving dermatologists, rheumatologists, and other specialists. Systemic therapies such as corticosteroids, antimalarials, immunosuppressive agents, and biologics may be used to control the disease activity. In addition, local treatments such as intralesional steroid injections or surgical excision of lesions may be considered for refractory cases.

Encephalitis is defined as inflammation of the brain parenchyma, which is often caused by viral infections but can also be due to bacterial, fungal, or parasitic infections, autoimmune disorders, or exposure to toxins. The infection or inflammation can cause various symptoms such as headache, fever, confusion, seizures, and altered consciousness, ranging from mild symptoms to severe cases that can lead to brain damage, long-term disabilities, or even death.

The diagnosis of encephalitis typically involves a combination of clinical evaluation, imaging studies (such as MRI or CT scans), and laboratory tests (such as cerebrospinal fluid analysis). Treatment may include antiviral medications, corticosteroids, immunoglobulins, and supportive care to manage symptoms and prevent complications.

Cytophagocytosis is a medical term that refers to the process in which certain types of cells, particularly immune cells like macrophages, engulf and digest other smaller cells or particles. This process helps the body to eliminate foreign substances, cellular debris, and pathogens such as bacteria, viruses, and fungi.

During cytophagocytosis, the macrophage extends its pseudopodia (cytoplasmic extensions) to surround and engulf the target cell or particle, forming a vesicle called a phagosome. The phagosome then fuses with a lysosome, an organelle containing digestive enzymes, which breaks down the contents of the phagosome into smaller molecules that can be used by the macrophage for energy or eliminated as waste products.

Cytophagocytosis is an essential part of the immune system's defense mechanisms and plays a crucial role in maintaining tissue homeostasis and preventing infection and disease.

There are many diseases that can affect cats, and the specific medical definitions for these conditions can be quite detailed and complex. However, here are some common categories of feline diseases and examples of each:

1. Infectious diseases: These are caused by viruses, bacteria, fungi, or parasites. Examples include:
* Feline panleukopenia virus (FPV), also known as feline parvovirus, which can cause severe gastrointestinal symptoms and death in kittens.
* Feline calicivirus (FCV), which can cause upper respiratory symptoms such as sneezing and nasal discharge.
* Feline leukemia virus (FeLV), which can suppress the immune system and lead to a variety of secondary infections and diseases.
* Bacterial infections, such as those caused by Pasteurella multocida or Bartonella henselae, which can cause abscesses or other symptoms.
2. Neoplastic diseases: These are cancerous conditions that can affect various organs and tissues in cats. Examples include:
* Lymphoma, which is a common type of cancer in cats that can affect the lymph nodes, spleen, liver, and other organs.
* Fibrosarcoma, which is a type of soft tissue cancer that can arise from fibrous connective tissue.
* Squamous cell carcinoma, which is a type of skin cancer that can be caused by exposure to sunlight or tobacco smoke.
3. Degenerative diseases: These are conditions that result from the normal wear and tear of aging or other factors. Examples include:
* Osteoarthritis, which is a degenerative joint disease that can cause pain and stiffness in older cats.
* Dental disease, which is a common condition in cats that can lead to tooth loss, gum inflammation, and other problems.
* Heart disease, such as hypertrophic cardiomyopathy (HCM), which is a thickening of the heart muscle that can lead to congestive heart failure.
4. Hereditary diseases: These are conditions that are inherited from a cat's parents and are present at birth or develop early in life. Examples include:
* Polycystic kidney disease (PKD), which is a genetic disorder that causes cysts to form in the kidneys and can lead to kidney failure.
* Hypertrophic cardiomyopathy (HCM), which can be inherited as an autosomal dominant trait in some cats.
* Progressive retinal atrophy (PRA), which is a group of genetic disorders that cause degeneration of the retina and can lead to blindness.

Biliary cirrhosis is a specific type of liver cirrhosis that results from chronic inflammation and scarring of the bile ducts, leading to impaired bile flow, liver damage, and fibrosis. It can be further classified into primary biliary cholangitis (PBC) and secondary biliary cirrhosis. PBC is an autoimmune disease, while secondary biliary cirrhosis is often associated with chronic gallstones, biliary tract obstruction, or recurrent pyogenic cholangitis. Symptoms may include fatigue, itching, jaundice, and abdominal discomfort. Diagnosis typically involves blood tests, imaging studies, and sometimes liver biopsy. Treatment focuses on managing symptoms, slowing disease progression, and preventing complications.

Cattle diseases are a range of health conditions that affect cattle, which include but are not limited to:

1. Bovine Respiratory Disease (BRD): Also known as "shipping fever," BRD is a common respiratory illness in feedlot cattle that can be caused by several viruses and bacteria.
2. Bovine Viral Diarrhea (BVD): A viral disease that can cause a variety of symptoms, including diarrhea, fever, and reproductive issues.
3. Johne's Disease: A chronic wasting disease caused by the bacterium Mycobacterium avium subspecies paratuberculosis. It primarily affects the intestines and can cause severe diarrhea and weight loss.
4. Digital Dermatitis: Also known as "hairy heel warts," this is a highly contagious skin disease that affects the feet of cattle, causing lameness and decreased productivity.
5. Infectious Bovine Keratoconjunctivitis (IBK): Also known as "pinkeye," IBK is a common and contagious eye infection in cattle that can cause blindness if left untreated.
6. Salmonella: A group of bacteria that can cause severe gastrointestinal illness in cattle, including diarrhea, dehydration, and septicemia.
7. Leptospirosis: A bacterial disease that can cause a wide range of symptoms in cattle, including abortion, stillbirths, and kidney damage.
8. Blackleg: A highly fatal bacterial disease that causes rapid death in young cattle. It is caused by Clostridium chauvoei and vaccination is recommended for prevention.
9. Anthrax: A serious infectious disease caused by the bacterium Bacillus anthracis. Cattle can become infected by ingesting spores found in contaminated soil, feed or water.
10. Foot-and-Mouth Disease (FMD): A highly contagious viral disease that affects cloven-hooved animals, including cattle. It is characterized by fever and blisters on the feet, mouth, and teats. FMD is not a threat to human health but can have serious economic consequences for the livestock industry.

It's important to note that many of these diseases can be prevented or controlled through good management practices, such as vaccination, biosecurity measures, and proper nutrition. Regular veterinary care and monitoring are also crucial for early detection and treatment of any potential health issues in your herd.

Erythema is a term used in medicine to describe redness of the skin, which occurs as a result of increased blood flow in the superficial capillaries. This redness can be caused by various factors such as inflammation, infection, trauma, or exposure to heat, cold, or ultraviolet radiation. In some cases, erythema may also be accompanied by other symptoms such as swelling, warmth, pain, or itching. It is a common finding in many medical conditions and can vary in severity from mild to severe.

There is no medical definition for "dog diseases" as it is too broad a term. However, dogs can suffer from various health conditions and illnesses that are specific to their species or similar to those found in humans. Some common categories of dog diseases include:

1. Infectious Diseases: These are caused by viruses, bacteria, fungi, or parasites. Examples include distemper, parvovirus, kennel cough, Lyme disease, and heartworms.
2. Hereditary/Genetic Disorders: Some dogs may inherit certain genetic disorders from their parents. Examples include hip dysplasia, elbow dysplasia, progressive retinal atrophy (PRA), and degenerative myelopathy.
3. Age-Related Diseases: As dogs age, they become more susceptible to various health issues. Common age-related diseases in dogs include arthritis, dental disease, cancer, and cognitive dysfunction syndrome (CDS).
4. Nutritional Disorders: Malnutrition or improper feeding can lead to various health problems in dogs. Examples include obesity, malnutrition, and vitamin deficiencies.
5. Environmental Diseases: These are caused by exposure to environmental factors such as toxins, allergens, or extreme temperatures. Examples include heatstroke, frostbite, and toxicities from ingesting harmful substances.
6. Neurological Disorders: Dogs can suffer from various neurological conditions that affect their nervous system. Examples include epilepsy, intervertebral disc disease (IVDD), and vestibular disease.
7. Behavioral Disorders: Some dogs may develop behavioral issues due to various factors such as anxiety, fear, or aggression. Examples include separation anxiety, noise phobias, and resource guarding.

It's important to note that regular veterinary care, proper nutrition, exercise, and preventative measures can help reduce the risk of many dog diseases.

Gnathostomiasis is a parasitic infection caused by the third-stage larvae of nematodes (roundworms) in the genus Gnathostoma. The infection typically occurs through the consumption of raw or undercooked freshwater fish, amphibians, or birds that contain the parasite's larvae.

The third-stage larvae penetrate the gastrointestinal tract and migrate to various tissues, including the skin, subcutaneous tissue, eyes, and central nervous system, causing cutaneous, ocular, or visceral lesions. The clinical manifestations of gnathostomiasis depend on the migration pathway and the organs involved.

Symptoms can range from mild dermatological reactions to severe neurological complications, such as eosinophilic meningitis or encephalitis. Diagnosis is often challenging due to its nonspecific clinical presentation and requires a high index of suspicion in travelers returning from endemic areas.

The disease is prevalent in Southeast Asia, East Asia, and Central and South America. Preventive measures include avoiding the consumption of raw or undercooked fish, amphibians, or birds in endemic regions and practicing good hygiene.

Panniculitis is a medical term that refers to inflammation of the subcutaneous fat, or the layer of fat located just beneath the skin. This condition can affect people of all ages and genders, although it is more commonly seen in middle-aged women. The inflammation can be caused by a variety of factors, including infections, autoimmune disorders, trauma, and medications.

The symptoms of panniculitis may include:

* Red, painful lumps or nodules under the skin
* Skin lesions that may be tender, warm, or bruised
* Swelling and redness in the affected area
* Fever, fatigue, and malaise (a general feeling of illness)

The diagnosis of panniculitis typically involves a physical examination, medical history, and sometimes a biopsy of the affected tissue. Treatment depends on the underlying cause of the inflammation and may include antibiotics, anti-inflammatory medications, or other therapies. In severe cases, hospitalization may be necessary to manage symptoms and prevent complications.

The brain is the central organ of the nervous system, responsible for receiving and processing sensory information, regulating vital functions, and controlling behavior, movement, and cognition. It is divided into several distinct regions, each with specific functions:

1. Cerebrum: The largest part of the brain, responsible for higher cognitive functions such as thinking, learning, memory, language, and perception. It is divided into two hemispheres, each controlling the opposite side of the body.
2. Cerebellum: Located at the back of the brain, it is responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
3. Brainstem: Connects the cerebrum and cerebellum to the spinal cord, controlling vital functions such as breathing, heart rate, and blood pressure. It also serves as a relay center for sensory information and motor commands between the brain and the rest of the body.
4. Diencephalon: A region that includes the thalamus (a major sensory relay station) and hypothalamus (regulates hormones, temperature, hunger, thirst, and sleep).
5. Limbic system: A group of structures involved in emotional processing, memory formation, and motivation, including the hippocampus, amygdala, and cingulate gyrus.

The brain is composed of billions of interconnected neurons that communicate through electrical and chemical signals. It is protected by the skull and surrounded by three layers of membranes called meninges, as well as cerebrospinal fluid that provides cushioning and nutrients.

Skin diseases, also known as dermatological conditions, refer to any medical condition that affects the skin, which is the largest organ of the human body. These diseases can affect the skin's function, appearance, or overall health. They can be caused by various factors, including genetics, infections, allergies, environmental factors, and aging.

Skin diseases can present in many different forms, such as rashes, blisters, sores, discolorations, growths, or changes in texture. Some common examples of skin diseases include acne, eczema, psoriasis, dermatitis, fungal infections, viral infections, bacterial infections, and skin cancer.

The symptoms and severity of skin diseases can vary widely depending on the specific condition and individual factors. Some skin diseases are mild and can be treated with over-the-counter medications or topical creams, while others may require more intensive treatments such as prescription medications, light therapy, or even surgery.

It is important to seek medical attention if you experience any unusual or persistent changes in your skin, as some skin diseases can be serious or indicative of other underlying health conditions. A dermatologist is a medical doctor who specializes in the diagnosis and treatment of skin diseases.

Cutaneous T-cell lymphoma (CTCL) is a type of cancer that affects T-cells, a specific group of white blood cells called lymphocytes. These cells play a crucial role in the body's immune system and help protect against infection and disease. In CTCL, the T-cells become malignant and accumulate in the skin, leading to various skin symptoms and lesions.

CTCL is a subtype of non-Hodgkin lymphoma (NHL), which refers to a group of cancers that originate from lymphocytes. Within NHL, CTCL is categorized as a type of extranodal lymphoma since it primarily involves organs or tissues outside the lymphatic system, in this case, the skin.

The two most common subtypes of CTCL are mycosis fungoides and Sézary syndrome:

1. Mycosis fungoides (MF): This is the more prevalent form of CTCL, characterized by patches, plaques, or tumors on the skin. The lesions may be scaly, itchy, or change in size, shape, and color over time. MF usually progresses slowly, with early-stage disease often confined to the skin for several years before spreading to lymph nodes or other organs.
2. Sézary syndrome (SS): This is a more aggressive form of CTCL that involves not only the skin but also the blood and lymph nodes. SS is characterized by the presence of malignant T-cells, known as Sézary cells, in the peripheral blood. Patients with SS typically have generalized erythroderma (reddening and scaling of the entire body), pruritus (severe itching), lymphadenopathy (swollen lymph nodes), and alopecia (hair loss).

The diagnosis of CTCL usually involves a combination of clinical examination, skin biopsy, and immunophenotyping to identify the malignant T-cells. Treatment options depend on the stage and subtype of the disease and may include topical therapies, phototherapy, systemic medications, or targeted therapies.

Dermatomyositis is a medical condition characterized by inflammation and weakness in the muscles and skin. It is a type of inflammatory myopathy, which means that it causes muscle inflammation and damage. Dermatomyositis is often associated with a distinctive rash that affects the skin around the eyes, nose, mouth, fingers, and toes.

The symptoms of dermatomyositis can include:

* Progressive muscle weakness, particularly in the hips, thighs, shoulders, and neck
* Fatigue
* Difficulty swallowing or speaking
* Skin rash, which may be pink or purple and is often accompanied by itching
* Muscle pain and tenderness
* Joint pain and swelling
* Raynaud's phenomenon, a condition that affects blood flow to the fingers and toes

The exact cause of dermatomyositis is not known, but it is believed to be related to an autoimmune response in which the body's immune system mistakenly attacks healthy tissue. Treatment for dermatomyositis typically involves medications to reduce inflammation and suppress the immune system, as well as physical therapy to help maintain muscle strength and function.

Acute necrotizing pancreatitis is a severe and potentially life-threatening form of acute pancreatitis, which is an inflammatory condition of the pancreas. In acute necrotizing pancreatitis, there is widespread death (necrosis) of pancreatic tissue due to autodigestion caused by the activation and release of digestive enzymes within the pancreas. This condition can lead to systemic inflammation, organ failure, and infection of the necrotic areas in the pancreas. It typically has a more complicated clinical course and worse prognosis compared to acute interstitial pancreatitis, which is another form of acute pancreatitis without significant necrosis.

Prednisolone is a synthetic glucocorticoid drug, which is a class of steroid hormones. It is commonly used in the treatment of various inflammatory and autoimmune conditions due to its potent anti-inflammatory and immunosuppressive effects. Prednisolone works by binding to specific receptors in cells, leading to changes in gene expression that reduce the production of substances involved in inflammation, such as cytokines and prostaglandins.

Prednisolone is available in various forms, including tablets, syrups, and injectable solutions. It can be used to treat a wide range of medical conditions, including asthma, rheumatoid arthritis, inflammatory bowel disease, allergies, skin conditions, and certain types of cancer.

Like other steroid medications, prednisolone can have significant side effects if used in high doses or for long periods of time. These may include weight gain, mood changes, increased risk of infections, osteoporosis, diabetes, and adrenal suppression. As a result, the use of prednisolone should be closely monitored by a healthcare professional to ensure that its benefits outweigh its risks.

Spontaneous remission in a medical context refers to the disappearance or significant improvement of symptoms of a disease or condition without any specific treatment being administered. In other words, it's a situation where the disease resolves on its own, without any apparent cause. While spontaneous remission can occur in various conditions, it is relatively rare and not well understood. It's important to note that just because a remission occurs without treatment doesn't mean that medical care should be avoided, as many conditions can worsen or lead to complications if left untreated.

Immunohistochemistry (IHC) is a technique used in pathology and laboratory medicine to identify specific proteins or antigens in tissue sections. It combines the principles of immunology and histology to detect the presence and location of these target molecules within cells and tissues. This technique utilizes antibodies that are specific to the protein or antigen of interest, which are then tagged with a detection system such as a chromogen or fluorophore. The stained tissue sections can be examined under a microscope, allowing for the visualization and analysis of the distribution and expression patterns of the target molecule in the context of the tissue architecture. Immunohistochemistry is widely used in diagnostic pathology to help identify various diseases, including cancer, infectious diseases, and immune-mediated disorders.

A fatal outcome is a term used in medical context to describe a situation where a disease, injury, or illness results in the death of an individual. It is the most severe and unfortunate possible outcome of any medical condition, and is often used as a measure of the severity and prognosis of various diseases and injuries. In clinical trials and research, fatal outcome may be used as an endpoint to evaluate the effectiveness and safety of different treatments or interventions.

A biopsy is a medical procedure in which a small sample of tissue is taken from the body to be examined under a microscope for the presence of disease. This can help doctors diagnose and monitor various medical conditions, such as cancer, infections, or autoimmune disorders. The type of biopsy performed will depend on the location and nature of the suspected condition. Some common types of biopsies include:

1. Incisional biopsy: In this procedure, a surgeon removes a piece of tissue from an abnormal area using a scalpel or other surgical instrument. This type of biopsy is often used when the lesion is too large to be removed entirely during the initial biopsy.

2. Excisional biopsy: An excisional biopsy involves removing the entire abnormal area, along with a margin of healthy tissue surrounding it. This technique is typically employed for smaller lesions or when cancer is suspected.

3. Needle biopsy: A needle biopsy uses a thin, hollow needle to extract cells or fluid from the body. There are two main types of needle biopsies: fine-needle aspiration (FNA) and core needle biopsy. FNA extracts loose cells, while a core needle biopsy removes a small piece of tissue.

4. Punch biopsy: In a punch biopsy, a round, sharp tool is used to remove a small cylindrical sample of skin tissue. This type of biopsy is often used for evaluating rashes or other skin abnormalities.

5. Shave biopsy: During a shave biopsy, a thin slice of tissue is removed from the surface of the skin using a sharp razor-like instrument. This technique is typically used for superficial lesions or growths on the skin.

After the biopsy sample has been collected, it is sent to a laboratory where a pathologist will examine the tissue under a microscope and provide a diagnosis based on their findings. The results of the biopsy can help guide further treatment decisions and determine the best course of action for managing the patient's condition.

In medical terms, the skin is the largest organ of the human body. It consists of two main layers: the epidermis (outer layer) and dermis (inner layer), as well as accessory structures like hair follicles, sweat glands, and oil glands. The skin plays a crucial role in protecting us from external factors such as bacteria, viruses, and environmental hazards, while also regulating body temperature and enabling the sense of touch.

Alpha 1-antitrypsin (AAT, or α1-antiproteinase, A1AP) is a protein that is primarily produced by the liver and released into the bloodstream. It belongs to a group of proteins called serine protease inhibitors, which help regulate inflammation and protect tissues from damage caused by enzymes involved in the immune response.

Alpha 1-antitrypsin is particularly important for protecting the lungs from damage caused by neutrophil elastase, an enzyme released by white blood cells called neutrophils during inflammation. In the lungs, AAT binds to and inhibits neutrophil elastase, preventing it from degrading the extracellular matrix and damaging lung tissue.

Deficiency in alpha 1-antitrypsin can lead to chronic obstructive pulmonary disease (COPD) and liver disease. The most common cause of AAT deficiency is a genetic mutation that results in abnormal folding and accumulation of the protein within liver cells, leading to reduced levels of functional AAT in the bloodstream. This condition is called alpha 1-antitrypsin deficiency (AATD) and can be inherited in an autosomal codominant manner. Individuals with severe AATD may require augmentation therapy with intravenous infusions of purified human AAT to help prevent lung damage.

"Relapsing febrile nodular nonsuppurative panniculitis". Archives of Internal Medicine. Chicago. 42 (3): 338. doi:10.1001/ ... "A CASE OF RELAPSING NON-SUPPURATIVE NODULAR PANNICULITIS, SHOWING PHAGOCYTOSIS OF SUBCUTANEOUS FAT-CELLS BY MACROPHAGES.*". ... It is a type of panniculitis. It is a rare disease seen in females 30-60 years of age. It is a recurring inflammation of fatty ... Alpha-1 antitrypsin deficiency panniculitis List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph ...
Weber, F. Parkes (July 1925). "A case of relapsing non-suppurative nodular panniculitis, showing phagocytosis of subcutaneous ... Pfeifer-)Weber-Christian disease: A skin disease characterized by fever and panniculitis with atrophy of the subcutaneous fatty ...
... panniculitis, lupus erythematosus MeSH C17.800.566.500 - panniculitis, nodular nonsuppurative MeSH C17.800.600.325 - dermatitis ... panniculitis, lupus erythematosus MeSH C17.300.710.500 - panniculitis, nodular nonsuppurative MeSH C17.300.710.600 - ... panniculitis, lupus erythematosus MeSH C17.300.480.680 - lupus nephritis MeSH C17.300.480.750 - lupus vasculitis, central ... panniculitis, peritoneal MeSH C17.300.775.099 - arthritis, rheumatoid MeSH C17.300.775.099.114 - arthritis, juvenile rheumatoid ...
... subacute migratory panniculitis of Vilanova and Piñol, subacute nodular migratory panniculitis) Cold panniculitis (popsicle ... relapsing febrile nonsuppurative panniculitis) Cutaneous congenital anomalies are a diverse group of disorders that result from ... sclerosing panniculitis, stasis panniculitis) Lipohypertrophy Localized lipodystrophy Neutrophilic lobular panniculitis Nodular ... alpha1-protease deficiency panniculitis, alpha1-proteinase deficiency panniculitis) Atrophic connective tissue panniculitis ...
"Relapsing febrile nodular nonsuppurative panniculitis". Archives of Internal Medicine. Chicago. 42 (3): 338. doi:10.1001/ ... "A CASE OF RELAPSING NON-SUPPURATIVE NODULAR PANNICULITIS, SHOWING PHAGOCYTOSIS OF SUBCUTANEOUS FAT-CELLS BY MACROPHAGES.*". ... It is a type of panniculitis. It is a rare disease seen in females 30-60 years of age. It is a recurring inflammation of fatty ... Alpha-1 antitrypsin deficiency panniculitis List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph ...
Weber-Christian disease is an eponym for a form of panniculitis, idiopathic nodular panniculitis, which is characterized by ... Panniculitis refers to a broad spectrum of diseases that involve inflammation of the subcutaneous fat layer of the skin. ... A case or relapsing nonsuppurative nodular panniculitis. Brit J Derm. 1925. 37:301. ... Weber-Christian disease is an eponym for a form of panniculitis, idiopathic nodular panniculitis, which is characterized by ...
61. PANNICULITIS, NODULAR NONSUPPURATIVE [ՊԱՆԻԿՈՒԼԻՏ ՀԱՆԳՈՒՑԱՎՈՐ ՉԹԱՐԱԽԱԿԱԼՎՈՂ] 12. PAIN, POSTOPERATIVE [ՑԱՎԵՐ ՀԵՏՎԻՐԱՀԱՏԱԿԱՆ] ... 62. PANNICULITIS, PERITONEAL [ՊԱՆԻԿՈՒԼԻՏ ՊԵՐԻՏՈՆԵԱԼ (ՈՐՈՎԱՅՆԱՄԶԱԲՈՐԲԱՅԻՆ)] 13. PAINT [ՆԵՐԿԵՐ] 63. PANOPHTHALMITIS [ՊԱՆՕՖԹԱԼՄԻԱ ... 59. PANNICULITIS [ՊԱՆԻԿՈՒԼԻՏ (ԵՆԹԱՄԱՇԿԱՅԻՆ ՃԱՐՊԱՇԱՐԱԿՑԱԿԱՆ ՇԵՐՏԻ ԲՈՐԲՈՔՈՒՄ)] 10. PAIN MEASUREMENT [ՑԱՎԵՐԻ ՀԵՏԱԶՈՏՈՒԹՅՈՒՆՆԵՐ] 60 ... PANNICULITIS, LUPUS ERYTHEMATOSUS [ՊԱՆԻԿՈՒԼԻՏ ԳԱՅԼԱԽՏԱՅԻՆ] 11. PAIN, INTRACTABLE [ՑԱՎԵՐ ԱՆՎԵՐԱՑՆԵԼԻ] ...
The skin pathology was consistent with non-suppurative nodular panniculitis. He was diagnosed with nodular panniculitis associa ... Pancreatic panniculitis with polyarthritis: PPP syndrome]. / Polyartritis, panniculitis en pancreatitis. Lichtenbeld, Erik A; ... TCL-084 Subcutaneous Panniculitis-Like T-Cell Lymphoma With Co-Existing Lupus Panniculitis: A Case Report. ... Unraveling subcutaneous panniculitis-like T-cell lymphoma: An association between subcutaneous panniculitis-like T-cell ...
... nonsuppurative form of panniculitis associated with abnormal metabolism of fat Allard.. Counter strike undetected multihack buy ... dispensing system for dispensing a quantity halo infinite fake duck server blocker disease Weber-Christian disease is a nodular ...
Nodular melanoma. *Nodular nonsuppurative panniculitis. *Nodular regenerative hyperplasia. *Noma. *Non 24 hour sleep wake ...
Panniculitis. *Erythema Induratum. *Panniculitis, Lupus Erythematosus. *Panniculitis, Nodular Nonsuppurative. *Panniculitis, ... Mycobacterium fortuitum panniculitis in a steroid-dependent asthmatic patient. J Am Acad Dermatol. 1998 Oct; 39(4 Pt 1):650-3. ... "Panniculitis" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Manosca F, Ariga R, Bengana C, Reddy VB, Loew J, Gattuso P. Fine-needle aspiration of subcutaneous panniculitis-like T-cell ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative. Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative. Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber Christian Disease use Panniculitis, Nodular Nonsuppurative Weber Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
H65 Nonsuppurative otitis media H65.0 Acute serous otitis media H65.1 Other acute nonsuppurative otitis media H65.2 Chronic ... M54.0 Panniculitis affecting regions of neck and back M54.1 Radiculopathy M54.2 Cervicalgia M54.3 Sciatica M54.4 Lumbago with ... nodular] non-Hodgkins lymphoma C82.0 "Non-Hodgkins lymphoma small cleaved cell, follicular" C82.1 "Non-Hodgkins lymphoma ... serous otitis media H65.3 Chronic mucoid otitis media H65.4 Other chronic nonsuppurative otitis media H65.9 "Nonsuppurative ...
Weber-Christian disease is an eponym for a form of panniculitis, idiopathic nodular panniculitis, which is characterized by ... Panniculitis refers to a broad spectrum of diseases that involve inflammation of the subcutaneous fat layer of the skin. ... A case or relapsing nonsuppurative nodular panniculitis. Brit J Derm. 1925. 37:301. ... Treatment of relapsing idiopathic nodular panniculitis with clofazimine. Br J Dermatol. 2005 Mar. 152(3):582-3. [QxMD MEDLINE ...
Panniculitis, Nodular Nonsuppurative / drug therapy* Actions. * Search in PubMed * Search in MeSH ... Cytophagic panniculitis. March LM, Webb J, Eckstein RP. March LM, et al. Aust N Z J Med. 1986 Jun;16(3):397-401. doi: 10.1111/j ... Treatment of cytophagic panniculitis with cyclosporin A. Royle G, Blacklock H, Miller M. Royle G, et al. Am J Med. 1992 Jun;92( ... Treatment of Weber-Christian panniculitis with cyclosporine A. Entzian P, Barth J, Mönig H, Ohnhaus EE, Kirch W. Entzian P, et ...
Nodular nonsuppurative panniculitis From NCATS Genetic and Rare Diseases Information Center File Formats Help:. How do I view ...
Nodular Nonsuppurative Panniculitides Nodular Nonsuppurative Panniculitis Nonsuppurative Panniculitides, Nodular Nonsuppurative ... Nodular Nonsuppurative Panniculitis. Nonsuppurative Panniculitides, Nodular. Nonsuppurative Panniculitis, Nodular. ... Panniculitis, Nodular Nonsuppurative - Preferred Concept UI. M0015818. Scope note. A form of panniculitis characterized by ... Panniculitis, Nodular Nonsuppurative Entry term(s). Disease, Weber-Christian ...
Panniculitis, Nodular Nonsuppurative Preferred Concept UI. M0015818. Scope Note. A form of panniculitis characterized by ... Panniculitis, Nodular Nonsuppurative Preferred Term Term UI T030168. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1965). ... Panniculitis, Nodular Nonsuppurative. Tree Number(s). C17.300.710.500. C17.800.566.500. Unique ID. D010201. RDF Unique ... 65; was PANNICULITIS 1963-64. History Note. 65; was PANNICULITIS 1963-64. Date Established. 1965/01/01. Date of Entry. 1999/01/ ...
Panniculitis, Nodular Nonsuppurative Preferred Concept UI. M0015818. Scope Note. A form of panniculitis characterized by ... Panniculitis, Nodular Nonsuppurative Preferred Term Term UI T030168. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1965). ... Panniculitis, Nodular Nonsuppurative. Tree Number(s). C17.300.710.500. C17.800.566.500. Unique ID. D010201. RDF Unique ... 65; was PANNICULITIS 1963-64. History Note. 65; was PANNICULITIS 1963-64. Date Established. 1965/01/01. Date of Entry. 1999/01/ ...
Systemic nodular panniculitis Current Synonym true false 56363014 Relapsing febrile nodular nonsuppurative panniculitis Current ... Relapsing febrile nodular nonsuppurative panniculitis (disorder). Code System Preferred Concept Name. Relapsing febrile nodular ...
Weber-Christian Disease use Panniculitis, Nodular Nonsuppurative. Weber-Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
BACKGROUND: Weber-Christian disease is a recurrent, non-suppurative, febrile nodular panniculitis, more frequent in young women ... The biopsy showed lobular panniculitis without vasculitis compatible with WeberChristian panniculitis. The patient was treated ... Paniculite Nodular não Supurativa/complicações , Paniculite Nodular não Supurativa/diagnóstico , Adulto Jovem ... Eritema Nodoso , Paniculite Nodular não Supurativa , Paniculite , Vasculite , Adulto , Biópsia , Eritema Nodoso/complicações , ...
Lupus Erythematosus Panniculitis, Nodular Nonsuppurative Panniculitis, Peritoneal Panophthalmitis Pansporablastina ... Pancuronium Pancytopenia Pandalidae Pandanaceae Pandemics Paneth Cells Panic Panic Disorder Panicum Panniculitis Panniculitis, ... Dental Focal Nodular Hyperplasia Focus Groups Foeniculum Folate Receptor 1 Folate Receptor 2 Folate Receptors, GPI-Anchored ... Nodular Goiter, Substernal Gold Gold Alloys Gold Colloid Gold Colloid, Radioactive Gold Compounds Gold Isotopes Gold ...
X PANNICULITIS, NODULAR NONSUPPURATIVE X LEG DERHATOSES P SYNDROBE Villarets syndrome (SYN) X PARALYSIS X CRANIAL NERVES X ... X PANNICULITIS, NODULAR NONSUPPURATIVE (SYN) Weber-Fechner law (HSH) X DIFFERENTIAL THRESHOLD Wedensky effect (IAF) X HEART ... X PANNICULITIS, NODULAR NONSUPPURATIVE N CHILD Rothmunds syndroae X skin DISEASES/congenital X CATARACT X PIGMENTATION ... cutaneous nodular (HSH) elastoidosis with cysts and comecones X SAIN DISEASES t EAVRE-RACOOCHOT SYNDROME cutaneum ...
Weber Christian Disease use Panniculitis, Nodular Nonsuppurative Weber Cockayne Syndrome use Epidermolysis Bullosa Simplex ...
" = "H65 Nonsuppurative otitis media" "H650" = "H65.0 Acute serous otitis media" "H651" = "H65.1 Other acute nonsuppurative ... " = "C82 Follicular [nodular] non?Hodgkins lymphoma" "C820" = "C82.0 Small cleaved cell, follicular" "C821" = "C82.1 Mixed ... " = "M54.0 Panniculitis affecting regions of neck and back" "M541" = "M54.1 Radiculopathy" "M542" = "M54.2 Cervicalgia" "M543 ... " = "H65.4 Other chronic nonsuppurative otitis media" "H659" = "H65.9 Nonsuppurative otitis media, unspecified" "H66" = "H66 ...
... nodular sclerosis of lymph nodes of axilla and upper limb (disorder) 188567005 Hodgkins disease, nodular sclerosis of intra- ... 202770004 Panniculitis of neck (disorder) 202744000 Cervical discitis (disorder) 206002004 Fetus or neonate affected by ... 194240006 Acute non-suppurative otitis media - serous (disorder) 194201001 Acute swimmers ear (disorder) 19416009 Congenital ... 188613007 Nodular lymphoma of lymph nodes of inguinal region and lower limb (disorder) 188612002 Nodular lymphoma of lymph ...
  • Weber-Christian disease is an eponym for a form of panniculitis, idiopathic nodular panniculitis, which is characterized by subcutaneous nodules, inflammatory cells in the fat lobules, and systemic symptoms. (medscape.com)
  • Another embodiment of the present invention is directed to a dispensing system for dispensing a quantity halo infinite fake duck server blocker disease Weber-Christian disease is a nodular, nonsuppurative form of panniculitis associated with abnormal metabolism of fat Allard. (arsevents.in)
  • It is a type of panniculitis. (wikipedia.org)
  • Erythema nodosum (EN), although relatively uncommon in the pediatric population, is the most frequent type of panniculitis in children. (bvsalud.org)
  • Increasing study and diagnostic sophistication have differentiated Weber-Christian disease from diseases such as lupus panniculitis, factitial panniculitis, panniculitis associated with pancreatic disease, histiocytic cytophagic panniculitis, and alpha1-antitrypsin deficiency panniculitis. (medscape.com)
  • INTRODUCTION: Pancreatic panniculitis is a rare skin manifestation of pancreatic disease. (bvsalud.org)
  • Pancreatic panniculitis can be a primary presenting feature and possible complication of pancreatic disease. (bvsalud.org)
  • Because the etiology is unknown, Weber-Christian disease is often referred to as idiopathic lobular panniculitis. (medscape.com)
  • Because its etiology is unknown, Weber-Christian disease is called idiopathic lobular panniculitis. (medscape.com)
  • CONCLUSION: The presence of ghost adipocytes is a rather unique histopathological feature consistent with pancreatic panniculitis and should be considered in combination with the overall clinical picture to determine the underlying etiology. (bvsalud.org)
  • The present study aimed to report all the cases of children admitted to our tertiary pediatric hospital with the diagnosis of EN to evaluate the epidemiology, clinical manifestations, etiology, treatment, and the course of this disease in the pediatric age. (bvsalud.org)
  • For example, a chart review of children and adolescents in Brazil over a 20-year period (1983-2002) found 35 pediatric and adolescent cases of panniculitis, with only 6 cases meeting criteria for Weber-Christian disease. (medscape.com)
  • The history of the eponym began in 1892 when Pfeifer first described the skin condition now known as Weber-Christian disease, or idiopathic lobular panniculitis. (medscape.com)
  • [ 7 ] At this time, the eponym Weber-Christian disease still refers to cases of nodular panniculitis with systemic signs and symptoms that remain idiopathic. (medscape.com)
  • Panniculitis refers to a broad spectrum of diseases that involve inflammation of the subcutaneous fat layer of the skin. (medscape.com)
  • Germline HAVCR2 mutations are frequently detected in subcutaneous panniculitis-like T-cell lymphoma (SPTCL) patients with/without hemophagocytic lymphohistiocytosis (HLH) but factors associated with variable manifestations remain undetermined. (bvsalud.org)
  • Sixty-eight patients with EN were included. (bvsalud.org)
  • In 30 patients (45%), no definitive diagnosis was reached, and they were defined as having idiopathic EN. (bvsalud.org)
  • They observed that cases of primary panniculitis are rare and that physicians may see only one or a few cases in a lifetime. (medscape.com)
  • Skin excisional biopsy was performed, and the results suggested panniculitis. (bvsalud.org)
  • Six cases with HAVCR2Y82C mutation manifested with HLH without panniculitis. (bvsalud.org)
  • A case or relapsing nonsuppurative nodular panniculitis. (medscape.com)
  • Treatment of relapsing idiopathic nodular panniculitis with clofazimine. (medscape.com)
  • Alpha-1 antitrypsin deficiency panniculitis List of cutaneous conditions Rapini, Ronald P. (wikipedia.org)
  • Velter C, Lipsker D. [Cutaneous panniculitis]. (medscape.com)
  • Treatment of cytophagic panniculitis with cyclosporin A. (nih.gov)