The term applied to a group of relatively uncommon inflammatory, maculopapular, scaly eruptions of unknown etiology and resistant to conventional treatment. Eruptions are both psoriatic and lichenoid in appearance, but the diseases are distinct from psoriasis, lichen planus, or other recognized dermatoses. Proposed nomenclature divides parapsoriasis into two distinct subgroups, PITYRIASIS LICHENOIDES and parapsoriasis en plaques (small- and large-plaque parapsoriasis).
Photochemotherapy using PSORALENS as the photosensitizing agent and ultraviolet light type A (UVA).
A chronic, malignant T-cell lymphoma of the skin. In the late stages, the LYMPH NODES and viscera are affected.
The use of ultraviolet electromagnetic radiation in the treatment of disease, usually of the skin. This is the part of the sun's spectrum that causes sunburn and tanning. Ultraviolet A, used in PUVA, is closer to visible light and less damaging than Ultraviolet B, which is ionizing.
A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. MYCOSIS FUNGOIDES; SEZARY SYNDROME; LYMPHOMATOID PAPULOSIS; and PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA are the best characterized of these disorders.

Demonstration of frequent occurrence of clonal T cells in the peripheral blood but not in the skin of patients with small plaque parapsoriasis. (1/13)

Clinical, immunohistological, and molecular biological data suggest the chronic dermatosis small plaque parapsoriasis (SPP) to be a precursor of mycosis fungoides (MF). However, most data are contradictory and confusing due to inexact definition of SPP. Recently, clonal T cells were detected in skin and blood samples of early MF. Because demonstration of identical T-cell clones in skin and blood of SPP patients would indicate a close relationship of SPP to MF, we investigated the clonality of skin and blood specimens from 14 well-defined SPP patients. By a polymerase chain reaction (PCR) amplifying T-cell receptor gamma rearrangements and subsequent high-resolution electrophoresis, clonal T cells were detected in 9 of 14 initial and 32 of 49 follow-up blood samples, but in 0 of 14 initial skin specimens. Even a clone-specific PCR showing the persistence of the initial blood T-cell clone in 20 of 20 follow-up samples, failed to detect the T-cell clone in the skin. In 2 patients, the clonal T cells were shown to be CD4(+). For the first time, the majority of SPP patients was shown to carry a T-cell clone in the peripheral blood. Although a relation between circulating clonal T cells and SPP cannot directly be proven by the applied techniques, our results indicate blood T-cell clonality to be a characteristic feature of SPP and CTCL because analysis of multiple controls and clinical workup of our SPP patients excluded other factors simulating or causing a clonal T-cell proliferation. A sufficient cutaneous antitumor response but also an extracutaneous origin of the T-cell clones might explain the failure to detect skin infiltrating clonal T cells.  (+info)

The aetiology of maculopapular rash diseases in Niteroi, State of Rio de Janeiro, Brazil: implications for measles surveillance. (2/13)

A study investigating the causes of rash diseases using systematic laboratory testing was conducted in Niteroi, Rio de Janeiro, between January 1994 to April 1998. Sera from 327 patients were tested for evidence of anti-rubella virus, measles virus, human parvovirus B19 and dengue fever virus specific immunoglobulin IgM and anti-human herpes virus type 6 (HHV-6) IgG antibodies. A laboratory confirmed diagnosis was achieved in 71.3% of the cases investigated: dengue fever (33.0%), rubella (20.2%), parvovirus B19 (9.2%), measles (6.7%) and HHV-6 (2.1%). No diagnosis was established for 94 cases (28.7%). An outbreak of measles was detected during 1997, with a peak in September and October. All of the diseases studied here presented with clinical features similar to measles and classical symptoms were found in all measles confirmed cases. The large overlap of combinations of signs and symptoms seen in this study highlights the difficulties of diagnosing a rash illness on clinical grounds alone.  (+info)

Mycosis fungoides. (3/13)

The case of a 46-year-old woman with poikiloderma vasculare atrophicans is discussed. It is a rare clinical form of patch-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectases.  (+info)

CD13 and TCR clone: markers of early mycosis fungoides. (4/13)

Making a differential diagnosis between early mycosis fungoides and parapsoriasis is often difficult at the clinical and histological level. The aim of this study was to explore markers that could help in this process. A total of 88 patients were included in 2 categories: large plaque parapsoriasis and digitiform parapsoriasis. A histological examination was performed for each patient, and expression of the antigen My7 (CD13), which is lacking in cutaneous T-lymphomas (but not in inflammatory lesions) and rearrangement of the T-cell receptor gene were analysed. A histological aspect of epidermotropic cutaneous T-cell lymphoma was observed in 23.5% of cases of large plaque parapsoriasis and 15% of cases of digitiform parapsoriasis. A disappearance of My7 antigen was noted in the 2 forms of parapsoriasis, more frequently when there was cutaneous T-cell lymphoma histology. A cutaneous clone was observed in 10.3% of cases of large plaque parapsoriasis, but not of digitiform parapsoriasis. For 3 patients, a cutaneous clone and a disappearance of My7 were associated with a non-specific histology. Considering these histological, immunological and molecular biological data, it appears that My7 antigen combined with T-cell clone may help the dermatologist to confirm the diagnosis of early mycosis fungoides. Moreover, further studies will determine whether CD13 is an early prognostic marker of evolution of a parapsoriasis to mycosis fungoides. Finally, these results demonstrate that digitiform parapsoriasis can be an early stage of MF.  (+info)

Cutaneous manifestations in renal failure patients: a case series. (5/13)

Cutaneous involvement in renal disease is due to a host of factors ranging from metabolic disturbances to immunosuppressive drugs. Herein we report a series of six cases of renal failure with varied cutaneous manifestations ranging from infections to neoplasms due to prolonged immunosuppression. Our first case had cutaneous cryptococcosis where skin lesions gave a clue to the diagnosis of altered sensorium and underlying meningitis. The second case initially presented with florid warts and was treated successfully but later presented with an explosive recurrence of skin lesions due to malignant transformation. Our third case had basal cell carcinoma over the presternal region that was successfully treated with liquid nitrogen cryotherapy. Our fourth case had diabetic nephropathy that presented with septicemia and purpura fulminans. The last case had cutaneous manifestations of drug therapy because of heparin infusion. To conclude, cutaneous manifestations in patients with renal failure are varied and a high degree of suspicion is needed for early diagnosis and aggressive treatment to effectively combat mortality and morbidity.  (+info)

Retroperitoneal liposarcoma associated with small plaque parapsoriasis. (6/13)

BACKGROUND: Extremely rare cases of paraneoplastic syndromes or ectopic production of proteins associated with liposarcoma are reported in literature. Production of Granulocyte-Colony Stimulating Factor, alpha-fetoprotein, paraneoplastic pemphigus and leucocytosis, Acrokeratosis paraneoplastica (Bazex's syndrome) are reported. The present report describes a case of retroperitoneal liposarcoma associated with small plaque parapsoriasis. Our search in the English literature of such a kind of association did not reveal any case reported. CASE PRESENTATION: A 74 year male patient was admitted to our hospital because of the presence of an abdominal mass in right iliac fossa. He also complained of a two-year history of psoriasiform eruptions. The CT scan showed a retroperitoneal pelvic mass. Therefore surgical resection of the tumor was performed. After surgery, the skin eruptions disappeared completely in seven days and so a diagnosis of parapsoriasis syndrome was done. CONCLUSION: Parallel disappearing of skin eruptions after surgery, typical clinical picture and not specific histology of the cutaneous lesions suggest the diagnosis of small plaque parapsoriasis. Therefore we propose to add Small Plaque Parapsoriasis to the list of paraneoplastic syndromes associated to liposarcoma.  (+info)

TCRgamma gene rearrangement analysis in skin samples and peripheral blood of mycosis fungoides patients. (7/13)

BACKGROUND: Diagnosing mycosis fungoides (MF) can be challenging in the early stage of the disease because histopathological features may simulate a variety of benign inflammatory skin diseases. Assessment of T-cell clonality was found to be useful in diagnosis and follow-up of patients. OBJECTIVE: In this study, PCR-based TCRgamma gene rearrangement analysis was performed in skin and peripheral blood samples of patients with MF treated at the two largest referral centers in Serbia, and the results obtained were correlated with clinical and follow-up data. METHODS: Skin and peripheral blood samples were obtained with informed consent from 37 patients treated at the Department of Dermatology of the Military Medical Academy and the Medical Center of Serbia from 2001 to 2006. The median time of follow-up was 4 years. Multiplex PCR was used for TCRgamma gene rearrangement analysis in skin and peripheral blood samples. Clonality results were correlated with the clinical data and disease course data. RESULTS: Monoclonality was detected in skin samples of 30/37 patients (81%), in 2/5 patients with large-plaque parapsoriasis (LPP), in 28/32 (88%) patients with histologically proven MF, and in 1/16 (6%) patients with benign inflammatory dermatoses. A monoclonal pattern in both skin and peripheral blood was detected in 7/16 (44%) patients in the late stage of the disease, and in 1/7 (14%) patients in the early stage of the disease. A dominant clone was found in both skin and peripheral blood in 1/4 patients in remission, 2/5 with a stable disease, and 4/9 (44%) with disease progression. CONCLUSION: TCR-gamma gene rearrangement analysis can be regarded as a useful adjunct to diagnosis of epidermotropic lymphoproliferative disorders. The presence of a dominant clone in both the skin and peripheral blood was more frequently detected in late stages and in patients with disease progression, confirming the usefulness of clonality detection by TCR-gamma gene rearrangement analysis in follow-up of patients with primary cutaneous T-cell lymphomas.  (+info)

The conundrum of parapsoriasis versus patch stage of mycosis fungoides. (8/13)

 (+info)

Parapsoriasis is a term used to describe two uncommon, chronic, and relatively benign inflammatory skin conditions. These are small plaque parapsoriasis (SPP) and large plaque parapsoriasis (LPP), also known as retiform or digitate dermatosis of Köbner.

Small plaque parapsoriasis is characterized by scaly, thin, pink to red patches or plaques, usually less than 3-5 cm in diameter. The lesions are often asymptomatic or mildly pruritic and can be found on the trunk and proximal extremities.

Large plaque parapsoriasis presents as larger, irregularly shaped, scaly patches or thin plaques, typically greater than 5 cm in diameter. The lesions are often asymptomatic but may occasionally be pruritic. LPP is considered a precursor to a rare cutaneous T-cell lymphoma called mycosis fungoides, especially when the lesions become thicker or more numerous over time.

It's important to note that these conditions can sometimes be challenging to diagnose and may require a skin biopsy for accurate diagnosis. Dermatologists and pathologists should carefully evaluate the clinical presentation, histopathological features, and any potential progression to ensure appropriate management.

PUVA therapy is a type of treatment that uses both medication and light to treat certain skin conditions, such as psoriasis, eczema, and cutaneous T-cell lymphoma. The name "PUVA" stands for Psoralen + UVA, which refers to the two main components of the therapy:

1. Psoralen: This is a medication that makes the skin more sensitive to light. It can be taken orally or applied directly to the skin in the form of a cream or bath.
2. UVA: This stands for Ultraviolet A, which is a type of light that is part of the natural sunlight spectrum. In PUVA therapy, the skin is exposed to a controlled dose of UVA light in a special booth or room.

When psoralen is introduced into the body, it absorbs into the skin and makes it more sensitive to UVA light. When the skin is then exposed to UVA light, it triggers a chemical reaction that slows down the growth of affected skin cells. This helps to reduce inflammation, scaling, and other symptoms associated with the skin condition being treated.

It's important to note that PUVA therapy can have side effects, including sunburn, itching, redness, and an increased risk of skin cancer over time. As such, it is typically used as a second-line treatment when other therapies have not been effective, and it is closely monitored by a healthcare professional to ensure its safe and effective use.

Mycosis fungoides is the most common type of cutaneous T-cell lymphoma (CTCL), a rare cancer that affects the skin's immune system. It is characterized by the infiltration of malignant CD4+ T-lymphocytes into the skin, leading to the formation of patches, plaques, and tumors. The disease typically progresses slowly over many years, often starting with scaly, itchy rashes that can be mistaken for eczema or psoriasis. As the disease advances, tumors may form, and the lymphoma may spread to other organs, such as the lymph nodes, lungs, or spleen. Mycosis fungoides is not contagious and cannot be spread from person to person. The exact cause of mycosis fungoides is unknown, but it is thought to result from a combination of genetic, environmental, and immune system factors.

Ultraviolet (UV) therapy, also known as phototherapy, is a medical treatment that uses ultraviolet light to treat various skin conditions. The UV light can be delivered through natural sunlight or artificial sources, such as specialized lamps or lasers.

In medical settings, controlled doses of UV light are used to target specific areas of the skin. The most common type of UV therapy is narrowband UVB (NB-UVB) phototherapy, which uses a specific wavelength of UVB light to treat conditions such as psoriasis, eczema, vitiligo, and dermatitis.

The goal of UV therapy is to reduce inflammation, slow skin cell growth, and improve the overall appearance of the skin. It is important to note that while UV therapy can be effective in treating certain skin conditions, it also carries risks such as skin aging and an increased risk of skin cancer. Therefore, it should only be administered under the supervision of a qualified healthcare professional.

Cutaneous T-cell lymphoma (CTCL) is a type of cancer that affects T-cells, a specific group of white blood cells called lymphocytes. These cells play a crucial role in the body's immune system and help protect against infection and disease. In CTCL, the T-cells become malignant and accumulate in the skin, leading to various skin symptoms and lesions.

CTCL is a subtype of non-Hodgkin lymphoma (NHL), which refers to a group of cancers that originate from lymphocytes. Within NHL, CTCL is categorized as a type of extranodal lymphoma since it primarily involves organs or tissues outside the lymphatic system, in this case, the skin.

The two most common subtypes of CTCL are mycosis fungoides and Sézary syndrome:

1. Mycosis fungoides (MF): This is the more prevalent form of CTCL, characterized by patches, plaques, or tumors on the skin. The lesions may be scaly, itchy, or change in size, shape, and color over time. MF usually progresses slowly, with early-stage disease often confined to the skin for several years before spreading to lymph nodes or other organs.
2. Sézary syndrome (SS): This is a more aggressive form of CTCL that involves not only the skin but also the blood and lymph nodes. SS is characterized by the presence of malignant T-cells, known as Sézary cells, in the peripheral blood. Patients with SS typically have generalized erythroderma (reddening and scaling of the entire body), pruritus (severe itching), lymphadenopathy (swollen lymph nodes), and alopecia (hair loss).

The diagnosis of CTCL usually involves a combination of clinical examination, skin biopsy, and immunophenotyping to identify the malignant T-cells. Treatment options depend on the stage and subtype of the disease and may include topical therapies, phototherapy, systemic medications, or targeted therapies.

The word "parapsoriasis" was formed in 1902. The parapsoriasis groups, described and debated for nearly a century, has spawned ... 450 Large-plaque parapsoriasis Small-plaque parapsoriasis Pityriasis lichenoides Pityriasis lichenoides chronica Pityriasis ... Parapsoriasis refers to one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis ( ... There are some authors who prefer to limit the term "parapsoriasis" to large- and small-plaque variants only. However, the ...
... is a cutaneous condition, considered to be a type of large-plaque parapsoriasis. It is characterized by ... Parapsoriasis Poikiloderma vasculare atrophicans List of cutaneous conditions Lambert WC, Everett MA (Oct 1981). "The nosology ... of parapsoriasis". J. Am. Acad. Dermatol. 5 (4): 373-95. doi:10.1016/S0190-9622(81)70100-2. PMID 7026622. Rapini, Ronald P.; ...
... characteristically occurs with skin lesions that are round, oval, discrete patches or thin plaques, ... ISBN 0-7216-2921-0. Lambert WC, Everett MA (October 1981). "The nosology of parapsoriasis". J. Am. Acad. Dermatol. 5 (4): 373- ... 452 Parapsoriasis List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2- ...
Large-plaque parapsoriasis is a common associate of retiform parapsoriasis, can be accompanied by poikiloderma vasculare ... Large plaque parapsoriasis are skin lesions that may be included in the modern scheme of cutaneous conditions described as ... Large plaque parapsoriasis is usually a chronic condition that needs long-term treatment. List of cutaneous conditions Mycosis ... Parapsoriasis treatment consists primarily of light therapy (more specifically PUVA therapy or UVB therapy) possibly in ...
... acute guttate parapsoriasis, acute parapsoriasis, acute pityriasis lichenoides, Mucha-Habermann disease, parapsoriasis acuta, ... Large plaque parapsoriasis (parapsoriasis en plaques) Lennert lymphoma (lymphoepitheliod lymphoma) Leukemia cutis Lymphoma ... parapsoriasis lichenoides et varioliformis acuta, parapsoriasis varioliformis) Plasmacytoma Plasmacytosis Pleomorphic T-cell ... chronic guttate parapsoriasis, chronic pityriasis lichenoides, dermatitis psoriasiformis nodularis, parapsoriasis chronica, ...
Lambert WC, Everett MA (October 1981). "The nosology of parapsoriasis". Journal of the American Academy of Dermatology. 5 (4): ...
ISBN 0-7216-2921-0. Domínguez MA, Membrillo VG, Ramos GA (2004). "Large plaque parapsoriasis and PUVA-therapy. A case report". ... large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen.: 686 The ...
... parapsoriasis variagata, or "variegated" parapsoriasis). Parapsoriasis is a term first used by Brocq in 1902, intended to ... PVA fits within this updated view of parapsoriasis as a syndrome often associated with large plaque parapsoriasis and, or ... PVA is believed to be a syndrome closely associated with large-plaque parapsoriasis and its cohort retiform parapsoriasis; ... which is also associated with large plaque parapsoriasis. Large plaque parapsoriasis consists of inflamed, oddly discolored ( ...
Cutaneous T-cell lymphoma Parapsoriasis Pityriasis lichenoides List of cutaneous conditions Freedberg, et al. (2003). ...
Cutaneous T-cell lymphoma Pityriasis lichenoides Parapsoriasis List of cutaneous conditions Freedberg, et al. (2003). ...
Cutaneous T-cell lymphoma Parapsoriasis Secondary cutaneous CD30+ large cell lymphoma List of cutaneous conditions Helen H. ...
Patients can be misdiagnosed with a variety of benign skin conditions, including dermatitis, eczema, parapsoriasis, psoriasis, ...
... and even parapsoriasis. Similar to the Woodford & Barry study in 1977, Woodford & Haigh, 1979 sought to determine the potency ...
Topical nitrogen mustard therapy in patients with mycosis fungoides or parapsoriasis. J Eur Acad Dermatol Venereol. 2013 Feb;27 ...
696 Psoriasis and similar disorders 696.0 Psoriatic arthropathy 696.1 Other psoriasis and similar disorders 696.2 Parapsoriasis ...
Paraphilia Paraplegia Paraplegia-brachydactyly-cone shaped epiphysis Paraplegia-mental retardation-hyperkeratosis Parapsoriasis ...
... parapsoriasis and a form of dermatitis called "Duhring-Brocq disease" (named with Louis Adolphus Duhring and sometimes referred ...
... parapsoriasis MeSH C17.800.859.575.650 - pityriasis lichenoides MeSH C17.800.859.575.650.580 - lymphomatoid papulosis MeSH ...
The word "parapsoriasis" was formed in 1902. The parapsoriasis groups, described and debated for nearly a century, has spawned ... 450 Large-plaque parapsoriasis Small-plaque parapsoriasis Pityriasis lichenoides Pityriasis lichenoides chronica Pityriasis ... Parapsoriasis refers to one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis ( ... There are some authors who prefer to limit the term "parapsoriasis" to large- and small-plaque variants only. However, the ...
Parapsoriasis describes a group of cutaneous diseases that can be characterized by scaly patches or slightly elevated papules ... Hypopigmented parapsoriasis en plaque, a new, overlooked member of the parapsoriasis family: a report of 34 patients and a 7- ... encoded search term (Parapsoriasis) and Parapsoriasis What to Read Next on Medscape ... Parapsoriasis Differential Diagnoses. Updated: Oct 07, 2021 * Author: Henry K Wong, MD, PhD; Chief Editor: Dirk M Elston, MD ...
Parapsoriasis describes a group of cutaneous diseases that can be characterized by scaly patches or slightly elevated papules ... Hypopigmented parapsoriasis en plaque, a new, overlooked member of the parapsoriasis family: a report of 34 patients and a 7- ... encoded search term (Parapsoriasis) and Parapsoriasis What to Read Next on Medscape ... Shall we exclude parapsoriasis from the medical vocabulary?. J Cutan Pathol. 2021 Jul. 48 (7):833-836. [QxMD MEDLINE Link]. ...
Parapsoriasis - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional ... Large-Plaque Parapsoriasis on the Trunk. This photo shows dull, pink, scaly patches of large-plaque parapsoriasis on the back. ... Treatment of Parapsoriasis Treatment of small-plaque parapsoriasis is unnecessary but can include emollients, topical tar ... Small-plaque parapsoriasis is defined by lesions , 5 cm in diameter, whereas large-plaque parapsoriasis has lesions > 5 cm in ...
... or parapsoriasis (most commonly large-plaque parapsoriasis), which may progress over years to decades to early plaque-stage ... Some regard large-plaque parapsoriasis as patch-stage mycosis fungoides. (See the images below.) ...
L41.9 Parapsoriasis, unspecified. CPT Codes for Phototherapy. According to an article published in MDedge in July 2017, ...
Categories: Parapsoriasis Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 2 ...
8. Parapsoriasis en plaques and mycosis fungoides.. Khan M. Z Hautkr; 1974 Jun; 49(12):547-54. PubMed ID: 4853533. [No Abstract ... Parapsoriasis--to be or not be (mycosis fungoides)].. Goldberg I. Harefuah; 2012 Oct; 151(10):581-4, 604. PubMed ID: 23316666. ... Transformation of parapsoriasis into mycosis fungoides].. Kalamkarian AA; Sych LI; Orazymbetova ZhA. Vestn Dermatol Venerol; ... 2. If small plaque (digitate) parapsoriasis is a cutaneous T-cell lymphoma, even an abortive one, it must be mycosis ...
Parapsoriasis en Plaque,d,6986,,0,0,0,,, 2421,2934,Renal Colic,k,8765,KIDNEY;RENAL;NEPHRIC;NEPHRON;KIDNEYS;PAIN;ACHE;HURT;CRAMP ... Parapsoriasis,d,6986,,0,0,0,,, 288,2891,Atrial Septal Defect,h,8062,ATRIUM;ATRIAL,0,0,0,,, 289,5439,Enterobacter Gergoviae,i,,, ...
Parapsoriasis / diagnosis* Actions. * Search in PubMed * Search in MeSH * Add to Search ...
Parapsoriasis / chemically induced* Actions. * Search in PubMed * Search in MeSH * Add to Search ...
Plaque-stage parapsoriasis. * Patch-stage mycosis fungoides progressing to plaque stage, with cutaneous cigarette-paper ...
... including samples from skin cancers and parapsoriasis lesions, tested negative for cutavirus (1). Our discovery of cutavirus in ...
Parapsoriasis From NCATS Genetic and Rare Diseases Information Center. * Matrix metalloproteinase-2 promoter genotype as a ...
Buergers component is affected by a parapsoriasis of sequestration and dé in the health outcomes, which has necessity type. ...
Parapsoriasis en plaque has been suggested to be an early manifestation of mycosis fungoides (cutaneous T-cell lymphoma). We ... A Retrospective Study of the Probability of the Evolution of Parapsoriasis en Plaques into Mycosis Fungoides ... of patients with small plaque or large plaque parapsoriasis in a 26-year retrospective cohort analysis of 105 parapsoriasis ...
... parapsoriasis varioliformis acuta (Mucha-Haberman syndrome), rhabdomyolysis, photosensitization, arthralgia, periorbital edema ...
Parapsoriasis en Plaques Narrower Concept UI. M0015910. Terms. Parapsoriasis en Plaques Preferred Term Term UI T030326. Date04/ ... PITYRIASIS LICHENOIDES and parapsoriasis en plaques (small- and large-plaque parapsoriasis).. Terms. Parapsoriasis Preferred ... Parapsoriasis en Plaques NLM Classification #. WR 204. Online Note. use PARAPSORIASIS to search PARAKERATOSIS VARIEGATA 1966-78 ... Proposed nomenclature divides parapsoriasis into two distinct subgroups, PITYRIASIS LICHENOIDES and parapsoriasis en plaques ( ...
Parapsoriasis en Plaques Narrower Concept UI. M0015910. Terms. Parapsoriasis en Plaques Preferred Term Term UI T030326. Date04/ ... PITYRIASIS LICHENOIDES and parapsoriasis en plaques (small- and large-plaque parapsoriasis).. Terms. Parapsoriasis Preferred ... Parapsoriasis en Plaques NLM Classification #. WR 204. Online Note. use PARAPSORIASIS to search PARAKERATOSIS VARIEGATA 1966-78 ... Proposed nomenclature divides parapsoriasis into two distinct subgroups, PITYRIASIS LICHENOIDES and parapsoriasis en plaques ( ...
Parapsoriasis guttata Current Synonym true false 308760014 Parapsoriasis en gouttes Current Synonym true false ...
Parapsoriasis--to be or not be (mycosis fungoides)]. Goldberg, Ilan. Harefuah ; 151(10): 581-4, 604, 2012 Oct. ...
Moreover, we presented 6 vaccine-induced cases comprising LP, Urticarial vasculitis, PR, Parapsoriasis, and Localized Morphea. ...
Parapsoriasis. Pityriasis Lichenoides. Pityriasis Rosea. Lichenoid and Granulomatous Disorders. Lichen Planus. Lichen Nitidus. ...
You can see how this popup was set up in our step-by-step guide: https://wppopupmaker.com/guides/auto-opening-announcement-popups/. ...
All of this makes them ideal for phototherapy treatment of diseases such as psoriasis, parapsoriasis, vitiligo, atopic ...
  • Parapsoriasis refers to one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis (red, scaly lesions), rather than by their underlying cause. (wikipedia.org)
  • Parapsoriasis describes a group of clinically variable cutaneous diseases that can be characterized by scaly patches or slightly elevated papules and/or plaques dispersed on the trunk or proximal extremities, with some lesions that may have a resemblance to psoriasis-hence the nomenclature. (medscape.com)
  • Lo primero es bombardear a tu cuerpo de antioxidantes pero naturales y en este By juicing marijuana, you receive most of the medical benefits of the cannabis Make This Liver-Healing Juice To Combat Psoriasis and Other Skin Issues. (azenvilagom.hu)
  • Parapsoriasis, also known as Brocq's disease, is an umbrella term for several skin problems with similar signs to psoriasis. (newlifeticket.com)
  • PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: eczema, psoriasis, graft-versus-host disease, vitiligo, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen. (standardofcare.com)
  • Psoriasiform dermatoses represent a wide spectrum of inflammatory conditions, with several major forms represented by psoriasis, as the prototype of this category, followed by pustular psoriasis, Reiter's syndrome, pityriasis rubra pilaris, lichen simplex chronicus and large-plaques parapsoriasis. (doctorsbag.net)
  • MF presents as erythematous skin patches that are often confused for immune-related diseases like eczema, psoriasis, parapsoriasis, or pityriasis lichenoides. (targretinhcp.com)
  • 450 Large-plaque parapsoriasis Small-plaque parapsoriasis Pityriasis lichenoides Pityriasis lichenoides chronica Pityriasis lichenoides et varioliformis acuta Lymphomatoid papulosis Mycosis Fungoides Poikiloderma vasculare atrophicans List of cutaneous conditions Sehgal VN, Srivastava G, Aggarwal AK (2007). (wikipedia.org)
  • As the nomenclature and description of the disease spectrum under the descriptive term parapsoriasis evolved, the primary focus has been on the distinction of whether the disorder progresses to mycosis fungoides (MF) or cutaneous T-cell lymphoma (CTCL). (medscape.com)
  • A retrospective study of the probability of the evolution of parapsoriasis en plaques into mycosis fungoides. (msdmanuals.com)
  • We examined the immune activation in 20 patients with mycosis fungoides, 6 patients with erythrodermia of unknown origin (Pré-Sézary's syndrome), 5 with lymphomatoid papulosis, 4 with parapsoriasis, 2 with Sézary's syndrome, and 2 with actinic reticuloid, by measuring soluble interleukin-2 receptor levels in serum. (medicaljournals.se)
  • There are some authors who prefer to limit the term "parapsoriasis" to large- and small-plaque variants only. (wikipedia.org)
  • These disease processes are large plaque parapsoriasis and small plaque parapsoriasis. (medscape.com)
  • Small plaque parapsoriasis is a benign disorder that rarely if ever progresses. (medscape.com)
  • Large plaque parapsoriasis is more ominous in that many patients progress to MF/CTCL. (medscape.com)
  • Controversy exists currently in the classification of large plaque parapsoriasis because some believe it is equivalent to the earliest stage of CTCL, the patch stage. (medscape.com)
  • El-Darouti et al reported on a 7-year study of a hypopigmented disorder that the researchers believe should be classified as a new variant of parapsoriasis en plaque. (medscape.com)
  • No clear etiology for small plaque or large plaque parapsoriasis is known, and no specific association has been made with contact exposure or infections. (medscape.com)
  • Small plaque parapsoriasis likely is a reactive process of predominantly CD4 + T cells. (medscape.com)
  • Genotypic pattern observed in small plaque parapsoriasis is similar to that observed in chronic dermatitis, and the pattern of clonality of T cells is consistent with the response of a specific subset of T cells that have been stimulated by an antigen. (medscape.com)
  • Proposed nomenclature divides parapsoriasis into two distinct subgroups, PITYRIASIS LICHENOIDES and parapsoriasis en plaques (small- and large-plaque parapsoriasis). (sdsu.edu)
  • Large plaque parapsoriasis is a chronic inflammatory disorder, and the pathophysiology has been speculated to be long-term antigen stimulation. (medscape.com)
  • This photo shows large-plaque parapsoriasis on the buttocks, characterized by thin, dull, pink, and slightly scaly patches. (msdmanuals.com)
  • This photo shows dull, pink, scaly patches of large-plaque parapsoriasis on the back. (msdmanuals.com)
  • Sometimes digitate plaques develop along the dermatomes, especially on the flanks and abdomen, in small-plaque parapsoriasis. (msdmanuals.com)
  • 5 cm, transformation into CTCL is extremely rare in small-plaque parapsoriasis. (msdmanuals.com)
  • Following 4 months of succesful therapy, he developed an indolent tumor on his right chin and parapsoriasis en plaque on the lower arms and legs. (karger.com)
  • Large plaque parapsoriasis is a type of Broca's disease characterized by a large-focal skin lesion with a high risk of developing T-cell lymphoma. (medic-journal.com)
  • a variant of parapsoriasis in which the plaques are large. (icdlist.com)
  • Lambert, WC & Everett, MA 1981, ' The nosology of parapsoriasis ', Journal of the American Academy of Dermatology , vol. 5, no. 4, pp. 373-395. (mssm.edu)
  • Habe seit 8 Jahren Parapsoriasis en Plaques (durch Biopsie gesichert, keine Beschwerd. (psoriasis-netz.de)
  • The initiating cause of parapsoriasis is unknown, but the diseases likely represent different stages in a continuum of lymphoproliferative disorders from chronic dermatitis stimulated by activated T cells to frank malignancy of cutaneous T-cell lymphoma (CTCL). (medscape.com)
  • 10] Nevertheless, a hint to the verity of this hypothesis is the recent identification of increased telomerase activity in T cells from CTCL at low-grade stages, high-grade lymphoma, and parapsoriasis, which is activity not exhibited in normal T cells. (medscape.com)
  • Thus, periodic clinical follow-up and biopsies may help identify progression of parapsoriasis to CTCL. (msdmanuals.com)
  • Parapsoriasis refers to a group of skin diseases characterized by maculopapular or scaly lesions. (msdmanuals.com)
  • Parapsoriasis describes a poorly understood, etiologically heterogeneous and poorly distinguished group of diseases that share clinical features. (msdmanuals.com)
  • But the scariest skin development was a condition called parapsoriasis, which can be a precursor to T-cell lymphoma. (healthline.com)
  • L41.9 is a billable ICD-10 code used to specify a medical diagnosis of parapsoriasis, unspecified. (icdlist.com)
  • Diagnosis of parapsoriasis is based on clinical appearance and distribution. (msdmanuals.com)
  • but otherwise the diagnosis of parapsoriasis is clinical. (msdmanuals.com)
  • Pityriasis lichenoides variants describe scaly dermatoses with necrotic papules that are clinically and histologically different from parapsoriasis. (medscape.com)
  • The parapsoriasis groups, described and debated for nearly a century, has spawned a confusing nomenclature. (wikipedia.org)
  • Current terminology of parapsoriasis refers to 2 disease processes that are caused by T-cell-predominant infiltrates in the skin. (medscape.com)
  • a subgroup of parapsoriasis itself divided into acute and chronic forms. (icdlist.com)
  • Parapsoriasis is a group of uncommon but not rare disorders that was created in 1902 as part of a now long forgotten scheme to classify all inflammatory dermatoses. (mssm.edu)
  • Southern blot analysis of T-cell receptor genes from parapsoriasis does not identify a dominant clone of T cells. (medscape.com)
  • This graph shows the total number of publications written about "Parapsoriasis" by people in this website by year, and whether "Parapsoriasis" was a major or minor topic of these publications. (sdsu.edu)
  • Below are the most recent publications written about "Parapsoriasis" by people in Profiles. (sdsu.edu)
  • 450 Large-plaque parapsoriasis Small-plaque parapsoriasis Pityriasis lichenoides Pityriasis lichenoides chronica Pityriasis lichenoides et varioliformis acuta Lymphomatoid papulosis Mycosis Fungoides Poikiloderma vasculare atrophicans List of cutaneous conditions Sehgal VN, Srivastava G, Aggarwal AK (2007). (wikipedia.org)
  • Kreuter A, Bischoff S, Skrygan M, Wieland U, Brockmeyer NH, Stücker M. High association of human herpesvirus 8 in large-plaque parapsoriasis and mycosis fungoides. (medscape.com)
  • Large plaque parapsoriasis. (medscape.com)
  • Parapsoriasis en plaques is a relatively rare group of disorders which has been classified into small plaque parapsoriasis (SPP) and large plaque parapsoriasis (LPP) according to the size of the lesions. (nature.com)
  • This photo shows large-plaque parapsoriasis on the buttocks, characterized by thin, dull, pink, and slightly scaly patches. (msdmanuals.com)
  • This photo shows dull, pink, scaly patches of large-plaque parapsoriasis on the back. (msdmanuals.com)
  • Classic mycosis fungoides is usually preceded by a nonspecific, indolent inflammatory process manifesting as atopic dermatitis, nonspecific chronic dermatitis, or parapsoriasis (most commonly large-plaque parapsoriasis), which may progress over years to decades to early plaque-stage mycosis fungoides. (medscape.com)
  • Some regard large-plaque parapsoriasis as patch-stage mycosis fungoides. (medscape.com)
  • We explored the disease course of patients with small plaque or large plaque parapsoriasis in a 26-year retrospective cohort analysis of 105 parapsoriasis patients, who were clinically and histopathologically followed up in Helsinki and Tampere University Hospitals. (medicaljournals.se)
  • Proposed nomenclature divides parapsoriasis into two distinct subgroups, PITYRIASIS LICHENOIDES and parapsoriasis en plaques (small- and large-plaque parapsoriasis). (nih.gov)
  • If small plaque (digitate) parapsoriasis is a cutaneous T-cell lymphoma, even an 'abortive' one, it must be mycosis fungoides! (medscape.com)
  • Burg G, Dummer R, Nestle FO, Doebbeling U, Haeffner A. Cutaneous lymphomas consist of a spectrum of nosologically different entities including mycosis fungoides and small plaque parapsoriasis. (medscape.com)
  • Hofer A, Cerroni L, Kerl H, Wolf P. Narrowband (311-nm) UV-B therapy for small plaque parapsoriasis and early-stage mycosis fungoides. (medscape.com)
  • Lindahl LM, Fenger-Gron M, Iversen L. Topical nitrogen mustard therapy in patients with mycosis fungoides or parapsoriasis. (medscape.com)
  • A retrospective study of the probability of the evolution of parapsoriasis en plaques into mycosis fungoides. (msdmanuals.com)
  • Eczema parapsoriasis or early mycosis fungoides? (dermpedia.org)
  • 1. Small plaque (digitate) parapsoriasis is an 'abortive cutaneous T-cell lymphoma' and is not mycosis fungoides. (nih.gov)
  • 3. Cutaneous lymphomas consist of a spectrum of nosologically different entities including mycosis fungoides and small plaque parapsoriasis. (nih.gov)
  • 4. The conundrum of parapsoriasis versus patch stage of mycosis fungoides. (nih.gov)
  • 8. Parapsoriasis en plaques and mycosis fungoides. (nih.gov)
  • 12. [Transformation of parapsoriasis into mycosis fungoides]. (nih.gov)
  • 19. A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: report of a case and comparative retrospective study of 27 cases of "nonprogressive" small plaque parapsoriasis. (nih.gov)
  • Parapsoriasis en plaque has been suggested to be an early manifestation of mycosis fungoides (cutaneous T-cell lymphoma). (medicaljournals.se)
  • All of this makes them ideal for phototherapy treatment of diseases such as psoriasis, parapsoriasis, vitiligo, atopic dermatitis, and mycosis fungoides. (medlamps.co.uk)
  • 12) Authors of most textbooks of dermatology and dermatopathology consider guttate parapsoriasis and digitate dermatosis to be variants of small plaque parapsoriasis which, they aver, is not related to mycosis fungoides. (comparewords.com)
  • Parapsoriasis refers to one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis (red, scaly lesions), rather than by their underlying cause. (wikipedia.org)
  • Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques. (medscape.com)
  • Psoriasis and parapsoriasis en plaques are chronic inflammatory skin diseases, both representing therapeutic challenge in daily practice and adversely affecting the quality of life. (nature.com)
  • We now report that hydrogen water, an effective ROS scavenger, has significant and rapid improvement in disease severity and quality of life for patients with psoriasis and parapsoriasis en plaques. (nature.com)
  • Up to date, hydrogen water (solubilized H 2 ) as a treatment strategy for psoriasis-associated skin lesions has been tried by few case reports 21 , and neither has hydrogen water for patients with parapsoriasis en plaques. (nature.com)
  • MF presents as erythematous skin patches that are often confused for immune-related diseases like eczema, psoriasis, parapsoriasis, or pityriasis lichenoides. (targretinhcp.com)
  • Digitate dermatosis (small-plaque parapsoriasis). (medscape.com)
  • Parapsoriasis refers to a group of skin diseases characterized by maculopapular or scaly lesions. (msdmanuals.com)
  • however, 21 skin samples, including samples from skin cancers and parapsoriasis lesions, tested negative for cutavirus ( 1 ). (cdc.gov)
  • Herzinger T, Degitz K, Plewig G, Rocken M. Treatment of small plaque parapsoriasis with narrow-band (311 nm) ultraviolet B: a retrospective study. (medscape.com)
  • There are some authors who prefer to limit the term "parapsoriasis" to large- and small-plaque variants only. (wikipedia.org)
  • Small plaque parapsoriasis. (medscape.com)
  • Hypopigmented parapsoriasis en plaque, a new, overlooked member of the parapsoriasis family: a report of 34 patients and a 7-year experience. (medscape.com)
  • There are a few reports of ichthyotic manifestation of MF, but only one report of this presentation in Parapsoriasis. (iranjd.ir)
  • Analysis of p53 gene mutations in parapsoriasis. (medscape.com)
  • We present a case of ichthyosiform Parapsoriasis in a 22-year-old woman with hyperpigmented ichthyosiform scaly patches on her trunk and extremities. (iranjd.ir)