DiseasesChemicals and Drugs
ParonychiaDermatologic Agents
Paronychia
An inflammatory reaction involving the folds of the skin surrounding the fingernail. It is characterized by acute or chronic purulent, tender, and painful swellings of the tissues around the nail, caused by an abscess of the nail fold. The pathogenic yeast causing paronychia is most frequently Candida albicans. Saprophytic fungi may also be involved. The causative bacteria are usually Staphylococcus, Pseudomonas aeruginosa, or Streptococcus. (Andrews' Diseases of the Skin, 8th ed, p271)
Dermatologic Agents
Drugs used to treat or prevent skin disorders or for the routine care of skin.

Onychomycosis caused by Blastoschizomyces capitatus. (1/24)

Blastoschizomyces capitatus was cultured from the nail of a healthy patient with onychomycosis. The identity of the isolate was initially established by standard methods and ultrastructural analysis and was verified by molecular probing. Strains ATCC 200929, ATCC 62963, and ATCC 62964 served as reference strains for these analyses. To our knowledge, this is the first case of nail infection secondary to paronychia caused by this organism reported in the English literature.  (+info)

A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours. (2/24)

Capecitabine and docetaxel are both active against a variety of solid tumours, while their toxicity profiles only partly overlap. This phase I study was performed to determine the maximum tolerated dose (MTD) and side-effects of the combination, and to establish whether there is any pharmacokinetic interaction between the two compounds. Thirty-three patients were treated with capecitabine administered orally twice daily on days 1-14, and docetaxel given as a 1 h intravenous infusion on day 1. Treatment was repeated every 3 weeks. The dose of capecitabine ranged from 825 to 1250 mg m(-2) twice a day and of docetaxel from 75 to 100 mg m(-2). The dose-limiting toxicity (DLT) was asthenia grade 2-3 at a dose of 1000 mg m(-2) bid of capecitabine combined with docetaxel 100 mg m(-2). Neutropenia grade 3-4 was common (68% of courses), but complicated by fever in only 2.4% of courses. Other non-haematological toxicities were mild to moderate. There was no pharmacokinetic interaction between the two drugs. Tumour responses included two complete responses and three partial responses. Capecitabine 825 mg m(-2) twice a day plus docetaxel 100 mg m(-2) was tolerable, as was capecitabine 1250 mg m(-2) twice a day plus docetaxel 75 mg m(-2).  (+info)

Paronychia in association with indinavir treatment. (3/24)

To assess a possible association between antiretroviral treatment and paronychia, we conducted a retrospective cohort study of 288 human immunodeficiency virus-positive protease inhibitor recipients. Indinavir treatment-adjusted for age, sex, CD4 count, diabetes status and other antiretroviral drug exposures-was significantly associated with paronychia of the great toe (hazard ratio 4.7; 95% confidence interval 1.6-13.9).  (+info)

Acute and chronic paronychia. (4/24)

Paronychia is one of the most common infections of the hand. Clinically, paronychia presents as an acute or a chronic condition. It is a localized, superficial infection or abscess of the paronychial tissues of the hands or, less commonly, the feet. Any disruption of the seal between the proximal nail fold and the nail plate can cause acute infections of the eponychial space by providing a portal of entry for bacteria. Treatment options for acute paronychias include warm-water soaks, oral antibiotic therapy and surgical drainage. In cases of chronic paronychia, it is important that the patient avoid possible irritants. Treatment options include the use of topical antifungal agents and steroids, and surgical intervention. Patients with chronic paronychias that are unresponsive to therapy should be checked for unusual causes, such as malignancy.  (+info)

Subungal abcesses secondary to paclitaxel. (5/24)

Various cutaneous side effects, including nail changes, have been associated with taxane chemotherapeutic agents, but usually docetaxel has been implicated. We report a patient with acute paronychia due to paclitaxel administered for treatment of breast cancer.  (+info)

Paronychia due to Prevotella bivia that resulted in amputation: fast and correct bacteriological diagnosis is crucial. (6/24)

Prevotella bivia is mainly associated with endometritis. The case of a patient with paronychia in a thumb due to P. bivia resulting in osteitis and amputation is reported. The species was not acknowledged in the first bacterial culture 2 weeks before surgery.  (+info)

Best evidence topic report. Incision and drainage preferable to oral antibiotics in acute paronychial nail infection? (7/24)

A short cut review was carried out to establish whether incision and drainage or antibiotics was best for acute paronychia. No relevant papers were found using the reported search. There is currently no evidence that oral antibiotics are any better or worse than incision and drainage for acute paronychiae.  (+info)

Chronic paronychia--putting a finger on the evidence. (8/24)

At first glance it seemed a minor problem, but the look on my new patient's face suggested otherwise. His finger had been painful for months and this week it had become worse. His swollen, erythematous nail fold, absent cuticle, and mildly dystrophic nail painted a typical picture of chronic paronychia. Assuming an acute bacterial superinfection, I prescribed a course of antibiotics, but my patient needed advice on treatment of the underlying condition. Another general practitioner had arranged fungal cultures, which had grown candida. Would antifungals be the best treatment? My patient and I agreed to meet in a week to assess his response to the antibiotics and to discuss treatment of the underlying chronic paronychia.  (+info)

Paronychia is a common, usually painful infection of the skin fold surrounding the nail plate, often caused by Staphylococcus aureus or Streptococcus pyogenes, and can be acute or chronic, primarily differentiated by duration and the presence of underlying conditions.

Paronychia is a medical condition that refers to an infection around the nail fold, which is the skin located at the sides and the base of the fingernail or toenail. It can be caused by bacteria, fungi, or sometimes even viruses. Paronychia can be acute (sudden onset, often due to bacterial infection) or chronic (persistent, often due to yeast or fungal infection). Symptoms may include redness, swelling, pain, pus-filled blisters, and in severe cases, destruction of the nail plate. Treatment typically involves antibiotics for bacterial infections, antifungal medications for fungal infections, warm soaks, and sometimes drainage of pus if necessary.

Dermatologic agents are medications, including topical creams, gels, lotions, and solutions, that are used to treat various skin conditions, such as acne, eczema, psoriasis, and fungal infections, by either suppressing the immune system, reducing inflammation, or inhibiting the growth of microorganisms.

Dermatologic agents are medications, chemicals, or other substances that are applied to the skin (dermis) for therapeutic or cosmetic purposes. They can be used to treat various skin conditions such as acne, eczema, psoriasis, fungal infections, and wounds. Dermatologic agents include topical corticosteroids, antibiotics, antifungals, retinoids, benzoyl peroxide, salicylic acid, and many others. They can come in various forms such as creams, ointments, gels, lotions, solutions, and patches. It is important to follow the instructions for use carefully to ensure safety and effectiveness.

InfectionChronicOnychomycosisRednessAnti Paronychia Relief OilIngrown toenailsFungalNailsTypes of paronychiaCuticleCause paronychiaPainfulRecurrentHerpetic whitlowInfectionsInflammation of the nail foldAntibioticMoistureCommonlyCaryophyllaceaeFingernailCanadensisCaused by bacteriaFoldDiagnosisFoldsSystemicToesRelief PatchTreatmentYeastDrainageFingersSkinTendernessOccurPerennial
Infection35
  • An infection of the cuticle secondary to a splinter Left and right ring fingers of the same person: The distal phalanx of the finger on the right exhibits swelling due to acute paronychia. (wikipedia.org)
  • Chronic paronychia is most often caused by a yeast infection of the soft tissues around the nail but can also be traced to a bacterial infection. (wikipedia.org)
  • Acute paronychia is an infection of the folds of tissue surrounding the nail of a finger or, less commonly, a toe, lasting less than six weeks. (wikipedia.org)
  • 339 Chronic paronychia is an infection of the folds of tissue surrounding the nail of a finger or, less commonly, a toe, lasting more than six weeks. (wikipedia.org)
  • 660 In chronic paronychia, the cuticle separates from the nail plate, leaving the region between the proximal nail fold and the nail plate vulnerable to infection. (wikipedia.org)
  • 254 Generally, acute paronychia is pyogenic, as it is usually caused by a bacterial infection. (wikipedia.org)
  • Differential diagnosis of paronychia includes: Cellulitis is a superficial infection and presents as erythema and swelling to the affected portion of the body with no area of fluctuance. (wikipedia.org)
  • It is important to not confuse this with a felon or a paronychia as incision and drainage of herpetic whitlow could result in a secondary bacterial infection and failure to heal. (wikipedia.org)
  • Paronychia is a soft tissue infection around a fingernail or toenail that begins as cellulitis but that may progress to a definite abscess. (medscape.com)
  • In this case, the paronychia was due to infection after a hangnail was removed. (medscape.com)
  • Paronychia is a soft tissue infection around a fingernail. (medscape.com)
  • Paronychia is the most common hand infection in the United States, representing 35% of these disorders. (medscape.com)
  • Paronychia is a common infection that afflicts the skin around the nails. (news-medical.net)
  • Paronychia may be acute or chronic, depending upon the development of the infection over a few hours or lasting more than 6 weeks, respectively. (news-medical.net)
  • If the paronychia is part of a more systemic illness, features of generalized infection may present such as fever, malaise, joint pain and red streaks along the affected part of the body due to infected lymph vessels. (news-medical.net)
  • Paronychia is an infection of the folds of skin surrounding the fingernail. (handandwristinstitute.com)
  • Paronychia is a common infection and is usually diagnosed clinically based on a history of trauma to the nail fold and the symptoms described above. (handandwristinstitute.com)
  • While not fatal (or even really painful), Paronychia can be an annoying ailment at best, and the fact of the matter is that no infection should go untreated, as it could possibly develop into other conditions that are far less benign. (handandwristinstitute.com)
  • Paronychia is an infection that develops around the nails. (northstardermatology.com)
  • Paronychia is an infection of the nail fold caused by bacteria or yeast infections, and can happen anytime the skin around the nail has been compromised. (northstardermatology.com)
  • Acute paronychia may have a sudden onset and is often to due to localized Staph infection of the skin. (northstardermatology.com)
  • Paronychia is an infection of the fingernails or toenails. (healthline.com)
  • Acute paronychia is an acute inflammation of the nail fold and frequently results from minor trauma, such as an accidental break in the skin, a splinter in the distal edge of the nail, a thorn in the lateral groove, a hang nail, or excessive nail biting leading to infection of the surrounding soft tissues. (medscape.com)
  • Chronic paronychia is characterized by acute exacerbations of self-limiting inflammation and infection followed by remissions. (medscape.com)
  • Paronychia is an infection of the perionychium (also called eponychium), which is the epidermis bordering the nail. (capsulehealth.one)
  • Paronychia is nail inflammation that may result from trauma, irritation or infection. (wizzgoo.com)
  • Paronychia with candida tends to develop slowly and cause persistent (chronic) infection. (wizzgoo.com)
  • Paronychia is a difficult condition to treat since it necessitates the elimination of the initial infection and the defense of newly-grown regions against reinfection. (wizzgoo.com)
  • Paronychia is an infection that develops underneath or adjacent to the nail. (slcpodiatrist.com)
  • An acute paronychia infection is most frequently brought on by staphylococci bacteria after an ingrown toenail has been allowed to invade the lateral fold tissue - or following a pedicure which involved cutting the cuticle. (slcpodiatrist.com)
  • Acute Paronychia Paronychia is infection of the periungual tissues. (msdmanuals.com)
  • Paronychia is an infection commonly affecting the skin around a finger or toe. (bestfootdoctorny.com)
  • The most effective treatment for paronychia depends on the severity and cause of the infection. (footspecialistindia.com)
  • For paronychia caused by bacteria, oral antibiotics may be prescribed to help clear the infection . (footspecialistindia.com)
  • If the paronychia is caused by a fungal infection, anti-fungal medications may be necessary. (footspecialistindia.com)
Chronic26
  • Paronychia is an inflammation of the skin around the nail, which can occur suddenly (acute), when it is usually due to the bacterium Staphylococcus aureus, or gradually (chronic) when it is commonly caused by Candida albicans. (wikipedia.org)
  • Chronic paronychia Acute paronychia is usually caused by bacteria. (wikipedia.org)
  • Paronychia aka "swollen nail" may be divided as occurring suddenly, acute, or gradually, chronic. (wikipedia.org)
  • [ 1 ] The 2 forms of paronychia, acute and chronic, usually differ in etiology, infectious agent, and treatment and are often considered separate entities. (medscape.com)
  • Clinically, paronychia presents as an acute or a chronic condition. (aafp.org)
  • In cases of chronic paronychia, it is important that the patient avoid possible irritants. (aafp.org)
  • Patients with chronic paronychias that are unresponsive to therapy should be checked for unusual causes, such as malignancy. (aafp.org)
  • Clinically, paronychia presents as an acute or chronic (longer than six weeks' duration) condition. (aafp.org)
  • People with occupations such as baker, bartender and dishwasher seem predisposed to developing chronic paronychia. (aafp.org)
  • There are two types of paronychia: acute and chronic. (handandwristinstitute.com)
  • Acute paronychia are typically bacterial in nature, while chronic paronychia are usually fungal infections, onychomycosis. (handandwristinstitute.com)
  • Chronic paronychia presents with recurrent bouts of swelling of the nail folds. (handandwristinstitute.com)
  • Soaks are useful in both acute and chronic paronychia. (handandwristinstitute.com)
  • Chronic paronychia is more prevalent in people who frequently have their hands in water including dishwashers, swimmers, bartenders and housekeepers. (northstardermatology.com)
  • Chronic paronychia commonly occurs in hands that are repeatedly exposed to water. (medscape.com)
  • Chronic paronychia (as opposed to the acute version) develops and heals slowly, though medication may provide quick relief from the pain. (slcpodiatrist.com)
  • The condition of chronic paronychia eventually breaks down the cuticle - causing it to separate from the toenail skin - giving organisms a free pass to colonization. (slcpodiatrist.com)
  • By completing curative care and correcting specific habits, you can prevent a recurrence of chronic paronychia altogether. (slcpodiatrist.com)
  • Chronic paronychia is recurrent or persistent nail fold inflammation, typically of the fingers. (msdmanuals.com)
  • Chronic paronychia is an inflammatory disorder of the nail fold skin. (msdmanuals.com)
  • Diagnosis of chronic paronychia is clinical. (msdmanuals.com)
  • Signs of chronic paronychia in this patient include absent cuticle, swollen proximal nail fold, and Beau lines of the nail plate. (msdmanuals.com)
  • Inflammation involving one or more nail folds which lasts for more than a month is called Chronic Paronychia condition. (footspecialistindia.com)
  • Avoidance of causative agents is the main stay of treatment for Chronic Paronychia. (footspecialistindia.com)
  • At Madurai Footcare Centre, we offer advanced treatments for both Acute and Chronic Paronychia conditions. (footspecialistindia.com)
  • or chronic, recurrent nail-fold inflammation ( paronychia ). (medscape.com)
Onychomycosis2
  • Using responses to a questionnaire from 1063 patients with disorders of the fingernails and/or toenails, the investigators found that the effect on quality of life was greatest in patients with nail problems resulting from trauma, infections (including onychomycosis and paronychia), structural abnormalities, and inflammatory diseases (including psoriasis). (medscape.com)
  • Sometimes fingernails damaged from fungus (Onychomycosis) or other skin diseases may predispose a person to get Paronychia. (orlandoskindoc.com)
Redness4
  • If the paronychia involves more extensive redness without abscess, or if the patient is diabetic or immunocompromised, oral antibiotics oral antifungals will be needed in addition to the soaks. (handandwristinstitute.com)
  • Paronychia symptoms include swelling, redness, pain, and pus-filled areas in or around the nail. (healthline.com)
  • Acute paronychia causes redness, warmth, and pain along the nail margin. (msdmanuals.com)
  • The symptoms of paronychia include pain,redness, swelling, and tenderness around the affected nail. (footspecialistindia.com)
Anti Paronychia Relief Oil6
  • How does ToenailPlus™ Anti Paronychia Relief Oil works? (wizzgoo.com)
  • The ToenailPlus™ Anti Paronychia Relief Oil treats and eliminates causative germs, softens buried toenails and calloused tissue, inhibits ingrown toenails, promotes healthy nail renewal, and straightens the nails. (wizzgoo.com)
  • ToenailPlus™ Anti Paronychia Relief Oil is soothing and promotes quicker healing of the toe. (wizzgoo.com)
  • ToenailPlus™ Anti Paronychia Relief Oil help relieve pain and make removal of ingrown and bacteria on nails easy, making your toes more comfortable from pain. (wizzgoo.com)
  • What makes ToenailPlus™ Anti Paronychia Relief Oil Special? (wizzgoo.com)
  • How Does the Anti Paronychia Relief Oil Work? (foxybeauty.net)
Ingrown toenails1
  • Now, let's explore the distinguishing factors of paronychia and ingrown toenails. (slcpodiatrist.com)
Fungal4
  • Paronychia may be due to bacterial, fungal or viral pathogens. (news-medical.net)
  • Fungal paronychia is more common in those who are diabetic, as well as those who wash their hands a lot. (news-medical.net)
  • It is possible to distinguish between fungal and bacterial paronychia by the speed at which the symptoms develop. (news-medical.net)
  • Management of fungal paronychia involves keeping the hands dry and applying an antifungal ointment is advised. (news-medical.net)
Nails6
  • Paronychias are localized, superficial infections or abscesses of the perionychium (epidermis bordering the nails). (aafp.org)
  • The delivery of potent antifungal/ anti bacterial drugs into the nails may be enhanced by the use of the following components: The preparation can be used to treat paronychia since it exhibits keratolytic and moisture-retention properties. (wizzgoo.com)
  • Paronychia is a common and painful condition that affects the skin surrounding the nails called proximal nail fold. (footspecialistindia.com)
  • Preventing paronychia involves good hygiene practices, such as regularly washing your hands and keeping your nails trimmed and clean. (footspecialistindia.com)
  • Shea butter, Clove oil, Eugenol, Red myrrh alcohol, Thyme extract, and Vitamin E are effective in treating paronychia by promoting healing of affected nails and combating any present fungus. (foxybeauty.net)
  • 2. Specially designed for ingrowing nails and paronychia patient. (vwoz.com)
Types of paronychia1
Cuticle2
  • 660 Acute paronychia is usually caused by direct or indirect trauma to the cuticle or nail fold, and may be from relatively minor events, such as dishwashing, an injury from a splinter or thorn, nail biting, biting or picking at a hangnail, finger sucking, an ingrown nail, or manicure procedures. (wikipedia.org)
  • Paronychia can develop when bacteria enter broken skin near the cuticle and nail fold, causing an infectio n. (wizzgoo.com)
Cause paronychia1
Painful3
  • Painful paronychia in association with a scaly, erythematous, keratotic rash (papules and plaques) of the ears, nose, fingers, and toes may be indicative of acrokeratosis paraneoplastica, which is associated with squamous-cell carcinoma of the larynx. (wikipedia.org)
  • Germs (bacteria) - These tend to cause sudden-onset (acute) paronychia which is painful. (wizzgoo.com)
  • In conclusion, paronychia can be a painful and uncomfortable condition, but with proper treatment, it can be easily managed. (footspecialistindia.com)
Recurrent1
  • If the Paronychia persists, or is frequently recurrent, it may result in changes to the nail. (orlandoskindoc.com)
Herpetic whitlow1
  • Paronychia is commonly misapplied as a synonym for herpetic whitlow or felon. (wikipedia.org)
Infections2
  • What are Nail Fold Infections (Paronychia)? (news-medical.net)
  • Paronychia is one of the most common infections of the hand. (aafp.org)
Inflammation of the nail fold1
  • Alternatively, paronychia may be divided as follows: Candidal paronychia is an inflammation of the nail fold produced by C. albicans. (wikipedia.org)
Antibiotic2
  • Treatment options for acute paronychias include warm-water soaks, oral antibiotic therapy and surgical drainage. (aafp.org)
  • More serious or persistent cases of paronychia may require prescription antibiotic or antifungal treatment. (northstardermatology.com)
Moisture3
  • Noninfectious causes of paronychia include contact irritants and excessive moisture. (aafp.org)
  • Moisture can also compound paronychia by providing an ideal environment for bacteria and fungi to thrive. (handandwristinstitute.com)
  • Likewise occupations and hobbies which expose hands repeatedly to moisture may result in paronychia. (handandwristinstitute.com)
Commonly2
  • Paronychia is an inflammation of the skin around the nail, which can occur suddenly, when it is usually due to the bacterium Staphylococcus aureus, or gradually when it is commonly caused by the fungus Candida albicans. (wikipedia.org)
  • Acute paronychia most commonly results from nail biting, finger sucking, aggressive manicuring, a hang nail or penetrating trauma, with or without retained foreign body 3 ( Figure 2 ) . (aafp.org)
Caryophyllaceae2
  • Androecial Evolution in the Dioecious Species of Paronychia (Caryophyllaceae). (botanyconference.org)
  • Flowers of Paronychia (Caryophyllaceae) are ancestrally hermaphroditic and staminodial, with the exception of the dioecious P. chartacea and P. minima . (botanyconference.org)
Fingernail2
  • In addition, it is useful to soak the fingernail(s) in hot water several times a day to soften the skin and relieve the pain and swelling in bacterial paronychia. (news-medical.net)
  • Sculptured fingernail (artificial nail) placement has also been shown to be associated with the development of paronychia. (aafp.org)
Canadensis1
  • Paronychia canadensis (L.) Alph. (usf.edu)
Caused by bacteria1
  • 310 Pyogenic paronychia is an inflammation of the folds of skin surrounding the nail caused by bacteria. (wikipedia.org)
Fold1
Diagnosis3
  • The diagnosis of paronychia is based primarily on patient history and physical examination. (medscape.com)
  • Diagnosis of paronychia is a purely clinical one. (news-medical.net)
  • I've seen doctors for toenail paronychia on two of my toes throughout the years, and each time they've given me a new diagnosis and course of therapy-and none of these expensive impressions were successful. (wizzgoo.com)
Folds1
Systemic1
  • Paronychia can occur with diabetes, drug-induced immunosuppression, or systemic diseases such as pemphigus. (wikipedia.org)
Toes1
  • Although paronychia is sometimes seen in the toes, the condition is more often on the fingers. (northstardermatology.com)
Relief Patch2
  • This German ToenailHeal Paronychia Relief Patch really does work! (yeardourshop.com)
  • How Does The German ToenailHeal Paronychia Relief Patch Work On Your Toenails? (yeardourshop.com)
Treatment4
  • This patient information and photograph on Orlando Paronychia Treatment is provided by John L. Meisenheimer, M.D. a board certified Dermatologist and skin care specialist based in Orlando, Florida. (orlandoskindoc.com)
  • It is important to seek treatment for a paronychia early before complications develop. (handandwristinstitute.com)
  • It is proven to be the best paronychia toenail treatment solution! (wizzgoo.com)
  • Paronychia can range from mild to severe, and the treatment is dependent on its severity. (bestfootdoctorny.com)
Yeast1
  • The pathogenic yeast causing paronychia is most frequently Candida albicans. (rush.edu)
Drainage1
  • Although prescribed antibiotics may provide fast relief for the intense pain of acute paronychia, its festering condition will usually require drainage. (slcpodiatrist.com)
Fingers2
  • Children are prone to acute paronychia through direct inoculation of fingers with flora from the mouth secondary to finger sucking and nail biting. (aafp.org)
  • Children who suck their fingers may experience paronychia for this reason. (handandwristinstitute.com)
Skin1
  • However, if left untreated, paronychia can cause long-term complications such as permanent scarring and deformation of skin tissue near the nail bed. (bestfootdoctorny.com)
Tenderness1
  • Patients with acute paronychia may report localized pain and tenderness of the perionychium. (aafp.org)
Occur1
  • Though paronychia may occur in tandem with an ingrown toenail, both conditions have unique symptoms, treatments, prognoses, and preemptive measures. (slcpodiatrist.com)
Perennial1
  • Paronychia jamesii is a PERENNIAL. (pfaf.org)