Cancers or tumors of the PENIS or of its component tissues.
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Neoplasms containing cyst-like formations or producing mucin or serum.
Tumors or cancer of the SKIN.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Tumors or cancers of the KIDNEY.
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)
Tumors or cancer of the THYROID GLAND.
Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
DNA present in neoplastic tissue.
Tumors or cancer of the LUNG.
Tumors or cancer of the PAROTID GLAND.

Male circumcision: assessment of health benefits and risks. (1/234)

OBJECTIVES: Globally approximately 25% of men are circumcised for religious, cultural, medical, or parental choice reasons. However, controversy surrounds the procedure, and its benefits and risks to health. We review current knowledge of the health benefits and risks associated with male circumcision. METHODS: We have used, where available, previously conducted reviews of the relation between male circumcision and specific outcomes as "benchmarks", and updated them by searching the Medline database for more recent information. RESULTS: There is substantial evidence that circumcision protects males from HIV infection, penile carcinoma, urinary tract infections, and ulcerative sexually transmitted diseases. We could find little scientific evidence of adverse effects on sexual, psychological, or emotional health. Surgical risks associated with circumcision, particularly bleeding, penile injury, and local infection, as well as the consequences of the pain experienced with neonatal circumcision, are valid concerns that require appropriate responses. CONCLUSION: Further analyses of the utility and cost effectiveness of male circumcision as a preventive health measure should, in the light of this information, be research and policy priorities. A decision as to whether to recommend male circumcision in a given society should be based upon an assessment of the risk for and occurrence of the diseases which are associated with the presence of the foreskin, versus the risk of the complications of the procedure. In order for individuals and their families to make an informed decision, they should be provided with the best available evidence regarding the known benefits and risks.  (+info)

Penile intraepithelial neoplasia--a veiled lesion in genitourinary medicine. (2/234)

Penile intraepithelial neoplasia (PIN) is a clinically well known condition. However, its diagnosis is often difficult. We present four cases of PIN, seen in our department. Various histological patterns ranging from PIN I to PIN III were noted in these cases.  (+info)

Tumours of the prostate and penis. (3/234)

Tumours of the male genital tract, excluding the testes, are relatively rare in the six major domestic animals. The most important tumours are prostate carcinoma and transmissible venereal tumour of the penis in dogs, fibropapilloma of the penis in bulls, squamous papilloma and squamous cell carcinoma in horses, and squamous papilloma in pigs. Four histological types of canine prostate carcinoma exist: alveolar papillary, acinar, organoid, and poorly differentiated. The biological behaviour of prostate carcinomas is similar to that in man, with frequent metastasis to the regional pelvic nodes, bones, and lungs. There appears to be no relationship between the common diffuse glandular hyperplasia and carcinoma in the prostate of dogs. A unique lesion of dogs is squamous metaplasia of the prostate related to estrogen-producing Sertoli cell tumours of the testis. Three different transmissible tumours of the penis occur in domestic animals. The canine venereal tumours can be transmitted only by intact tumour cells during licking and coital contact, whereas bovine fibropapillomas and porcine squamous papillomas can be transmitted by cell-free material. In cattle, the fibropapillomas are caused by the same virus that produces cutaneous papillomatosis. All three tumours are benign and usually regress spontaneously.  (+info)

Distinct patterns of alteration of myc genes associated with integration of human papillomavirus type 16 or type 45 DNA in two genital tumours. (4/234)

We previously described two genital carcinomas (IC2, IC4) containing human papillomavirus type 16 (HPV-16)- or HPV-18-related sequences integrated in chromosomal bands containing the c-myc (8q24) or N-myc (2p24) gene, respectively. The c-myc gene was rearranged and amplified in IC2 cells without evidence of overexpression. The N-myc gene was amplified and highly transcribed in IC4 cells. Here, the sequence of an 8039 bp IC4 DNA fragment containing the integrated viral sequences and the cellular junctions is reported. A 3948 bp segment of the genome of HPV-45 encompassing the upstream regulatory region and the E6 and E7 ORFs was integrated into the untranslated part of N-myc exon 3, upstream of the N-myc polyadenylation signal. Both N-myc and HPV-45 sequences were amplified 10- to 20-fold. The 3' ends of the major N-myc transcript were mapped upstream of the 5' junction. A minor N-myc/HPV-45 fusion transcript was also identified, as well as two abundant transcripts from the HPV-45 E6-E7 region. Large amounts of N-myc protein were detected in IC4 cells. A major alteration of c-myc sequences in IC2 cells involved the insertion of a non-coding sequence into the second intron and their co-amplification with the third exon, without any evidence for the integration of HPV-16 sequences within or close to the gene. Different patterns of myc gene alterations may thus be associated with integration of HPV DNA in genital tumours, including the activation of the protooncogene via a mechanism of insertional mutagenesis and/or gene amplification.  (+info)

Erythroplasia of queyrat: coinfection with cutaneous carcinogenic human papillomavirus type 8 and genital papillomaviruses in a carcinoma in situ. (5/234)

Erythroplasia of Queyrat is a carcinoma in situ that mainly occurs on the glans penis, the prepuce, or the urethral meatus of elderly males. Up to 30% progress to squamous cell carcinoma. The cause of erythroplasia of Queyrat is largely unknown. Human papillomavirus type 16 DNA has previously been detected only in very few distinctly characterized patients. We have investigated 12 paraffin-embedded biopsies from eight patients with penile erythroplasia of Queyrat and control biopsies of inflammatory penile lesions, of genital Bowen's disease, and of premalignant/malignant cervical or vulvar lesions by 10 different polymerase chain reaction protocols for the presence of cutaneous and genital/mucosal human papillomaviruses. Human papillomavirus typing was performed by sequencing (cloned) polymerase chain reaction products. Human papillomavirus DNA was detected in all erythroplasia of Queyrat patients and in none of the controls with inflammatory penile lesions. The rare cutaneous carcinogenic epidermodysplasia verruciformis-associated human papillomavirus type 8 was present in all erythroplasia of Queyrat patients and the genital high-risk human papillomavirus type 16 in seven of eight patients (88%). In addition to human papillomavirus type 8 and human papillomavirus type 16, four patients carried the genital carcinogenic human papillomavirus type 39 and/or type 51. All human papillomavirus type 8 sequences found in erythroplasia of Queyrat showed some polymorphism among each other and differed in specific nucleotide exchanges from the human papillomavirus type 8 reference sequence. Viral load determinations (human papillomavirus copies/beta-globin gene copies) by realtime polymerase chain reactions showed that the human papillomavirus type 16 levels in the erythroplasia of Queyrat biopsies were one to five orders of magnitude higher than the human papillomavirus type 8 levels. Human papillomavirus type 8 was not detected in cervical or vulvar precancerous and cancerous lesions and in Bowen's disease lesions that carried genital human papillomavirus types. The data suggest that in erythroplasia of Queyrat, in contrast to other genital neoplasias, a coinfection with human papillomavirus type 8 and carcinogenic genital human papillomavirus types occurs. The presence or absence of human papillomavirus type 8 might help to distinguish between penile erythroplasia of Queyrat and Bowen's diseases.  (+info)

Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. (6/234)

BACKGROUND: Human papillomavirus (HPV)-associated anogenital malignancies occur frequently in patients with human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS). The purpose of our study was to determine if the high frequency of these cancers is due to lifestyle factors associated with both HPV and HIV infections or to immunosuppression following HIV infection. METHODS: We studied invasive and in situ HPV-associated cancers among 309 365 U.S. patients with HIV infection/AIDS (257 605 males and 51 760 females) from 5 years before the date of AIDS onset to 5 years after this date. Sex-, race-, and age-standardized ratios of observed-to-expected cancers served as measures of relative risk (RR). Trend tests were used to evaluate changes in the RRs during the 10 years spanning AIDS onset. All statistical tests were two-sided. RESULTS: All HPV-associated cancers in AIDS patients occurred in statistically significant excess compared with the expected numbers of cancers. For in situ cancers, overall risks were significantly increased for cervical (RR = 4.6; 95% confidence interval [CI] = 4.3-5.0), vulvar/vaginal (RR = 3.9; 95% CI = 2.0-7. 0), anal (in females, RR = 7.8 [95% CI = 0.2-43.6]; in males, RR = 60.1 [95% CI = 49.2-72.7]), and penile (RR = 6.9; 95% CI = 4.2-10.6) cancers, and RRs increased during the 10 years spanning AIDS onset for carcinomas in situ of the cervix (P: for trend <.001), vulva/vagina (P: for trend =.04), and penis (P: for trend =.04). For invasive cancers, overall risks were significantly increased for cervical (RR = 5.4; 95% CI = 3.9-7.2), vulvar/vaginal (RR = 5.8; 95% CI = 3.0-10.2), and anal (RR = 6.8; 95% CI = 2.7-14.0) cancers in females and for anal (RR = 37.9; 95% CI = 33.0-43.4), penile (RR = 3. 7; 95% CI = 2.0-6.2), tonsillar (RR = 2.6; 95% CI = 1.8-3.8), and conjunctival (RR = 14.6; 95% CI = 5.8-30.0) cancers in males. However, RRs for invasive cancers changed little during the 10 years spanning AIDS onset. CONCLUSIONS: HPV-associated malignancies occur at increased rates in persons with HIV/AIDS. Increasing RRs for in situ cancers to and beyond the time of AIDS onset may reflect the gradual loss of control over HPV-infected keratinocytes with advancing immunosuppression. However, the lack of a similar increase for invasive HPV-associated cancers suggests that late-stage cancer invasion is not greatly influenced by immune status.  (+info)

Identification and functional analysis of sequence rearrangements in the long control region of human papillomavirus type 16 Af-1 variants isolated from Ugandan penile carcinomas. (7/234)

Human papillomavirus type 16 (HPV-16) is the predominant HPV isolate found in malignancies of male and female lower genital tracts. However, only a small percentage of individuals infected with high-risk HPVs develop a genital neoplasia, suggesting that additional events at both the cellular and the virus level are necessary for the progression to cancer, including genetic mutations/rearrangements of viral sequences involved in the oncogenic process. In this study, the genetic stability of the long control region (LCR) (nt 7289-114), which regulates expression levels of oncoproteins E6 and E7, was analysed in HPV-16 isolates from penile carcinoma (PC) biopsies of patients recruited from Uganda, one of the countries with the highest incidence of genital cancers in both men and women. Nucleotide changes within the LCR region typical of the African-1 (Af-1) lineage were observed in all HPV-16 isolates. Two out of five samples showed further rearrangements of the enhancer region. The functional activity of LCR with Af-1 mutations and/or rearrangements was evaluated by cloning each LCR into CAT expression vectors, followed by transfection in several epithelial and non-epithelial cell lines. CAT expression levels driven by a rearranged LCR were significantly higher than those driven by Af-1 or European prototype LCRs. Furthermore, in the NIH3T3 focus formation assay, the transforming activity of E6 and E7 genes, driven by a mutated or rearranged LCR, was 1.4- to 3.0-fold higher, respectively. These results indicate that rearrangements within the LCR of HPV-16 isolated from African PCs are frequently found (2 out of 5, 40%). It is also shown that increased HPV LCR activity is associated with an increased E6/E7-mediated in vitro transforming activity, suggesting that natural variants can play a major role in the pathogenesis of genital carcinomas.  (+info)

Intra-arterial chemotherapy in locally advanced or recurrent carcinomas of the penis and anal canal: an active treatment modality with curative potential. (8/234)

The prognosis of locally advanced or recurrent carcinomas of the penis (PE) and of the anal canal (AC) after conventional treatment is dismal. We report 16 patients (eight with AC carcinomas and eight with PE cancers) treated by intra-arterial (IA) chemotherapy. Fifteen of them were treated for locally advanced or recurrent disease and one in an adjuvant setting. The chemotherapy was administered via a femoral IA catheter with its tip located above the aortic bifurcation, under the inferior mesenteric artery. It consisted of eight push injections, given over a 48-h period, of the following drug combination: cisplatin 8.5 mg m(-2), 5-FU 275 mg m(-2), methotrexate 27.5 mg m(-2), mitomycin C 1.2 mg m(-2), and bleomycin 4 mg m(-2). Leucovorin was given po, 4 x 15 mg day(-1), during the chemotherapy and for 3 days thereafter. A total of 52 cycles of treatment were administered. Of the 15 patients evaluable for response, six obtained a CR (three PE, three AC) and eight a PR. Among the complete responders, four are alive and disease-free 2-15 years after treatment. The other patients enjoyed an objective response lasting 3-25 months (median 7 months). Four patients developed grade III/IV haematological toxicity with three episodes of febrile neutropenia, one of them with a fatal outcome due to patient's failure to obtain medical attention at the onset of his fever, one a grade III mucositis of the glans, and four a grade III/IV cutaneous toxicity, the latter caused by the IA administration of bleomycin. In conclusion, IA chemotherapy is effective and potentially curative in locoregionally advanced or recurrent carcinomas of the penis and of the anus. Its contribution in the primary management of advanced penile or anal carcinoma should be prospectively investigated.  (+info)

Penile neoplasms refer to abnormal growths or tumors in the penis. These can be benign (non-cancerous) or malignant (cancerous). The most common type of penile cancer is squamous cell carcinoma, which begins in the flat cells that line the surface of the penis. Other types of penile cancer include melanoma, basal cell carcinoma, and adenocarcinoma.

Benign penile neoplasms include conditions such as papillomas, condylomas, and peyronie's disease. These growths are usually not life-threatening, but they can cause discomfort, pain, or other symptoms that may require medical treatment.

It is important to note that any unusual changes in the penis, such as lumps, bumps, or sores, should be evaluated by a healthcare professional to determine the underlying cause and appropriate treatment.

Pancreatic neoplasms refer to abnormal growths in the pancreas that can be benign or malignant. The pancreas is a gland located behind the stomach that produces hormones and digestive enzymes. Pancreatic neoplasms can interfere with the normal functioning of the pancreas, leading to various health complications.

Benign pancreatic neoplasms are non-cancerous growths that do not spread to other parts of the body. They are usually removed through surgery to prevent any potential complications, such as blocking the bile duct or causing pain.

Malignant pancreatic neoplasms, also known as pancreatic cancer, are cancerous growths that can invade and destroy surrounding tissues and organs. They can also spread (metastasize) to other parts of the body, such as the liver, lungs, or bones. Pancreatic cancer is often aggressive and difficult to treat, with a poor prognosis.

There are several types of pancreatic neoplasms, including adenocarcinomas, neuroendocrine tumors, solid pseudopapillary neoplasms, and cystic neoplasms. The specific type of neoplasm is determined through various diagnostic tests, such as imaging studies, biopsies, and blood tests. Treatment options depend on the type, stage, and location of the neoplasm, as well as the patient's overall health and preferences.

Neoplasms are abnormal growths of cells or tissues in the body that serve no physiological function. They can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow growing and do not spread to other parts of the body, while malignant neoplasms are aggressive, invasive, and can metastasize to distant sites.

Neoplasms occur when there is a dysregulation in the normal process of cell division and differentiation, leading to uncontrolled growth and accumulation of cells. This can result from genetic mutations or other factors such as viral infections, environmental exposures, or hormonal imbalances.

Neoplasms can develop in any organ or tissue of the body and can cause various symptoms depending on their size, location, and type. Treatment options for neoplasms include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, among others.

Neoplasms: Neoplasms refer to abnormal growths of tissue that can be benign (non-cancerous) or malignant (cancerous). They occur when the normal control mechanisms that regulate cell growth and division are disrupted, leading to uncontrolled cell proliferation.

Cystic Neoplasms: Cystic neoplasms are tumors that contain fluid-filled sacs or cysts. These tumors can be benign or malignant and can occur in various organs of the body, including the pancreas, ovary, and liver.

Mucinous Neoplasms: Mucinous neoplasms are a type of cystic neoplasm that is characterized by the production of mucin, a gel-like substance produced by certain types of cells. These tumors can occur in various organs, including the ovary, pancreas, and colon. Mucinous neoplasms can be benign or malignant, and malignant forms are often aggressive and have a poor prognosis.

Serous Neoplasms: Serous neoplasms are another type of cystic neoplasm that is characterized by the production of serous fluid, which is a thin, watery fluid. These tumors commonly occur in the ovary and can be benign or malignant. Malignant serous neoplasms are often aggressive and have a poor prognosis.

In summary, neoplasms refer to abnormal tissue growths that can be benign or malignant. Cystic neoplasms contain fluid-filled sacs and can occur in various organs of the body. Mucinous neoplasms produce a gel-like substance called mucin and can also occur in various organs, while serous neoplasms produce thin, watery fluid and commonly occur in the ovary. Both mucinous and serous neoplasms can be benign or malignant, with malignant forms often being aggressive and having a poor prognosis.

Skin neoplasms refer to abnormal growths or tumors in the skin that can be benign (non-cancerous) or malignant (cancerous). They result from uncontrolled multiplication of skin cells, which can form various types of lesions. These growths may appear as lumps, bumps, sores, patches, or discolored areas on the skin.

Benign skin neoplasms include conditions such as moles, warts, and seborrheic keratoses, while malignant skin neoplasms are primarily classified into melanoma, squamous cell carcinoma, and basal cell carcinoma. These three types of cancerous skin growths are collectively known as non-melanoma skin cancers (NMSCs). Melanoma is the most aggressive and dangerous form of skin cancer, while NMSCs tend to be less invasive but more common.

It's essential to monitor any changes in existing skin lesions or the appearance of new growths and consult a healthcare professional for proper evaluation and treatment if needed.

Multiple primary neoplasms refer to the occurrence of more than one primary malignant tumor in an individual, where each tumor is unrelated to the other and originates from separate cells or organs. This differs from metastatic cancer, where a single malignancy spreads to multiple sites in the body. Multiple primary neoplasms can be synchronous (occurring at the same time) or metachronous (occurring at different times). The risk of developing multiple primary neoplasms increases with age and is associated with certain genetic predispositions, environmental factors, and lifestyle choices such as smoking and alcohol consumption.

Kidney neoplasms refer to abnormal growths or tumors in the kidney tissues that can be benign (non-cancerous) or malignant (cancerous). These growths can originate from various types of kidney cells, including the renal tubules, glomeruli, and the renal pelvis.

Malignant kidney neoplasms are also known as kidney cancers, with renal cell carcinoma being the most common type. Benign kidney neoplasms include renal adenomas, oncocytomas, and angiomyolipomas. While benign neoplasms are generally not life-threatening, they can still cause problems if they grow large enough to compromise kidney function or if they undergo malignant transformation.

Early detection and appropriate management of kidney neoplasms are crucial for improving patient outcomes and overall prognosis. Regular medical check-ups, imaging studies, and urinalysis can help in the early identification of these growths, allowing for timely intervention and treatment.

A "second primary neoplasm" is a distinct, new cancer or malignancy that develops in a person who has already had a previous cancer. It is not a recurrence or metastasis of the original tumor, but rather an independent cancer that arises in a different location or organ system. The development of second primary neoplasms can be influenced by various factors such as genetic predisposition, environmental exposures, and previous treatments like chemotherapy or radiation therapy.

It is important to note that the definition of "second primary neoplasm" may vary slightly depending on the specific source or context. In general medical usage, it refers to a new, separate cancer; however, in some research or clinical settings, there might be more precise criteria for defining and diagnosing second primary neoplasms.

Adenocarcinoma, mucinous is a type of cancer that begins in the glandular cells that line certain organs and produce mucin, a substance that lubricates and protects tissues. This type of cancer is characterized by the presence of abundant pools of mucin within the tumor. It typically develops in organs such as the colon, rectum, lungs, pancreas, and ovaries.

Mucinous adenocarcinomas tend to have a distinct appearance under the microscope, with large pools of mucin pushing aside the cancer cells. They may also have a different clinical behavior compared to other types of adenocarcinomas, such as being more aggressive or having a worse prognosis in some cases.

It is important to note that while a diagnosis of adenocarcinoma, mucinous can be serious, the prognosis and treatment options may vary depending on several factors, including the location of the cancer, the stage at which it was diagnosed, and the individual's overall health.

Thyroid neoplasms refer to abnormal growths or tumors in the thyroid gland, which can be benign (non-cancerous) or malignant (cancerous). These growths can vary in size and may cause a noticeable lump or nodule in the neck. Thyroid neoplasms can also affect the function of the thyroid gland, leading to hormonal imbalances and related symptoms. The exact causes of thyroid neoplasms are not fully understood, but risk factors include radiation exposure, family history, and certain genetic conditions. It is important to note that most thyroid nodules are benign, but a proper medical evaluation is necessary to determine the nature of the growth and develop an appropriate treatment plan.

Myeloproliferative disorders (MPDs) are a group of rare, chronic blood cancers that originate from the abnormal proliferation or growth of one or more types of blood-forming cells in the bone marrow. These disorders result in an overproduction of mature but dysfunctional blood cells, which can lead to serious complications such as blood clots, bleeding, and organ damage.

There are several subtypes of MPDs, including:

1. Chronic Myeloid Leukemia (CML): A disorder characterized by the overproduction of mature granulocytes (a type of white blood cell) in the bone marrow, leading to an increased number of these cells in the blood. CML is caused by a genetic mutation that results in the formation of the BCR-ABL fusion protein, which drives uncontrolled cell growth and division.
2. Polycythemia Vera (PV): A disorder characterized by the overproduction of all three types of blood cells - red blood cells, white blood cells, and platelets - in the bone marrow. This can lead to an increased risk of blood clots, bleeding, and enlargement of the spleen.
3. Essential Thrombocythemia (ET): A disorder characterized by the overproduction of platelets in the bone marrow, leading to an increased risk of blood clots and bleeding.
4. Primary Myelofibrosis (PMF): A disorder characterized by the replacement of normal bone marrow tissue with scar tissue, leading to impaired blood cell production and anemia, enlargement of the spleen, and increased risk of infections and bleeding.
5. Chronic Neutrophilic Leukemia (CNL): A rare disorder characterized by the overproduction of neutrophils (a type of white blood cell) in the bone marrow, leading to an increased number of these cells in the blood. CNL can lead to an increased risk of infections and organ damage.

MPDs are typically treated with a combination of therapies, including chemotherapy, targeted therapy, immunotherapy, and stem cell transplantation. The choice of treatment depends on several factors, including the subtype of MPD, the patient's age and overall health, and the presence of any comorbidities.

The term "DNA, neoplasm" is not a standard medical term or concept. DNA refers to deoxyribonucleic acid, which is the genetic material present in the cells of living organisms. A neoplasm, on the other hand, is a tumor or growth of abnormal tissue that can be benign (non-cancerous) or malignant (cancerous).

In some contexts, "DNA, neoplasm" may refer to genetic alterations found in cancer cells. These genetic changes can include mutations, amplifications, deletions, or rearrangements of DNA sequences that contribute to the development and progression of cancer. Identifying these genetic abnormalities can help doctors diagnose and treat certain types of cancer more effectively.

However, it's important to note that "DNA, neoplasm" is not a term that would typically be used in medical reports or research papers without further clarification. If you have any specific questions about DNA changes in cancer cells or neoplasms, I would recommend consulting with a healthcare professional or conducting further research on the topic.

Lung neoplasms refer to abnormal growths or tumors in the lung tissue. These tumors can be benign (non-cancerous) or malignant (cancerous). Malignant lung neoplasms are further classified into two main types: small cell lung carcinoma and non-small cell lung carcinoma. Lung neoplasms can cause symptoms such as cough, chest pain, shortness of breath, and weight loss. They are often caused by smoking or exposure to secondhand smoke, but can also occur due to genetic factors, radiation exposure, and other environmental carcinogens. Early detection and treatment of lung neoplasms is crucial for improving outcomes and survival rates.

Parotid neoplasms refer to abnormal growths or tumors in the parotid gland, which is the largest of the salivary glands and is located in front of the ear and extends down the neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign parotid neoplasms are typically slow-growing, painless masses that may cause facial asymmetry or difficulty in chewing or swallowing if they become large enough to compress surrounding structures. The most common type of benign parotid tumor is a pleomorphic adenoma.

Malignant parotid neoplasms, on the other hand, are more aggressive and can invade nearby tissues and spread to other parts of the body. They may present as rapidly growing masses that are firm or fixed to surrounding structures. Common types of malignant parotid tumors include mucoepidermoid carcinoma, adenoid cystic carcinoma, and squamous cell carcinoma.

The diagnosis of parotid neoplasms typically involves a thorough clinical evaluation, imaging studies such as CT or MRI scans, and fine-needle aspiration biopsy (FNAB) to determine the nature of the tumor. Treatment options depend on the type, size, and location of the neoplasm but may include surgical excision, radiation therapy, and chemotherapy.

Pathology of Testicular and Penile Neoplasms. Springer. p. 184. ISBN 978-3-319-27617-5. Nieschlag, Eberhard & Behre, Hermann ( ...
MeSH C12.294.260.500 - penile neoplasms MeSH C12.294.260.750 - prostatic neoplasms MeSH C12.294.260.937 - testicular neoplasms ... genital neoplasms, male MeSH C12.740.800.410.600 - penile neoplasms MeSH C12.740.800.410.650 - prostatic neoplasms MeSH C12.740 ... penile induration MeSH C12.294.494.591 - penile neoplasms MeSH C12.294.494.684 - phimosis MeSH C12.294.494.684.587 - ... 875 - testicular neoplasms MeSH C12.740.800.820 - urologic neoplasms MeSH C12.740.800.820.125 - bladder neoplasms MeSH C12.740. ...
Additional symptoms include neoplasm, cryptorchidism, ventricular septal defect, atrial septal defect, hernia, patent ductus ... arteriosus, Tetralogy of Fallot, and penile hypoplasia. This condition is caused by an autosomal dominant missense mutation in ...
... vaginal intraepithelial neoplasm (VAIN) anal dysplasia (also see: anal cancer) lichen sclerosus Bowen's disease (penile or ...
Penile Discharge". Signs and Symptoms. Lippincott Williams & Wilkins. ISBN 978-0-7817-7043-9. Compérat, Eva; Varinot, Justine ( ... 2016). "Immunochemical and molecular assessment of urothelial neoplasms and aspects of the 2016 World Health Organization ... Anterior urethral cancer Penile cancer Janisch, Florian; Abufaraj, Mohammad; Fajkovic, Harun; Kimura, Shoji; Iwata, Takehiro; ... Symptoms include blood in the urine, lump at end of penis, or bloody penile discharge. Diagnosis is established by ...
Table 3 from: Weiss, Lawrence M.; Gelb, Arnold B.; Jeffrey Medeiros, L. (1995). "Adult Renal Epithelial Neoplasms". American ... Penile, and Testicular Tumours". European Urology. 70 (1): 93-105. doi:10.1016/j.eururo.2016.02.029. PMID 26935559. ... of all kidney neoplasms. Based on its morphological features, PRCC can be classified into two main subtypes, which are type 1 ( ... "Enhancement characteristics of papillary renal neoplasms revealed on triphasic helical CT of the kidneys". AJR. American ...
... vulvar neoplasms MeSH C04.588.945.440 - genital neoplasms, male MeSH C04.588.945.440.715 - penile neoplasms MeSH C04.588. ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... bile duct neoplasms MeSH C04.588.274.120.250.250 - common bile duct neoplasms MeSH C04.588.274.120.401 - gallbladder neoplasms ... femoral neoplasms MeSH C04.588.149.721 - skull neoplasms MeSH C04.588.149.721.450 - jaw neoplasms MeSH C04.588.149.721.450.583 ...
They are comparable to pearly penile papules, which occur in males. VP are not infectious and not due to HPV. Diagnosis is by ... ISBN 978-1-119-48899-6. Sanchez, Isabella; Raffi, Jodie; Kraus, Christina N. (23 February 2022). "Vulvar Neoplasms (Part II)". ...
Pearly penile papules are also termed papillae coronae glandis and hirsutoid papillomas. The condition of having such papules ... Oral fibromas are not neoplasms; they are hyperplastic (i.e. overgrowth) reactions of fibrous tissue to local trauma or chronic ... Saardi KM, Dubin JM, Cardis MA (May 2021). "Images - Atypical presentation of pearly penile papules". Canadian Urological ... Connective and soft tissue neoplasms, Benign neoplasms). ... is the female equivalent of pearly penile papules in men. It ...
Ovarian germ cell tumor Penile cancer Kidney cancer Renal cell carcinoma Renal pelvis and ureter, transitional cell cancer* ... Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm ...
... familial Pemphigus vulgaris Pemphigus Pena-Shokeir syndrome Pendred syndrome Penile agenesis Penoscrotal transposition Penta X ... familial Pancreatic diseases Pancreatic islet cell neoplasm Pancreatic islet cell tumors Pancreatic lipomatosis duodenal ... et varioliformis acuta Pityriasis rubra pilaris Piussan-Lenaerts-Mathieu syndrome Placenta disorder Placenta neoplasm Placental ... retardation-hyperkeratosis Parapsoriasis Parasitophobia Parastremmatic dwarfism Parathyroid cancer Parathyroid neoplasm ...
Nguyen AH, Smith ML, Maranda EL, Punnen S (June 2016). "Clinical Features and Treatment of Penile Schwannoma: A Systematic ... Melanotic schwannoma is an uncommon, unique, and possibly cancerous neoplasm defined by epithelioid cells with variable-sized ...
Teichman JM, Sea J, Thompson IM, Elston DM (January 2010). "Noninfectious penile lesions". Am Fam Physician. 81 (2): 167-74. ... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... labial and penile and vulvar melanosis, melanotic macules) Nevus of Ito (nevus fuscoceruleus acromiodeltoideus) Nevus of Ota ( ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ...
When they appear on the penis, they are also called penile sebaceous glands. They appear as small, painless, raised, pale, red ... The pathologist must be careful to differentiate such lesions from salivary neoplasms with sebaceous cells, such as sebaceous ... Rane V, Read T (May 2013). "Penile appearance, lumps and bumps". Australian Family Physician. 42 (5): 270-4. PMID 23781523. ...
Low-magnification micrograph of penile verrucous carcinoma. The tumor is characterized by prominent papillomatosis. High ... neoplasms, and cysts, Carcinoma, Oral mucosal pathology, Oral neoplasia). ... "Organ-Sparing Surgery for a Giant Verrucous Carcinoma of the Penile Shaft: A Case Report and Review of the Literature". Case ...
... renal neoplasms are rare but usually are not benign. Renal neoplasms and abscesses are rare in ruminants. Obstructive uropathy ... "The Unique Penile Morphology of the Short-Beaked Echidna, Tachyglossus aculeatus". Sexual Development. 15 (4): 262-271. doi: ...
Top, J. G. B.; Heer, N.; Klein, W. R.; Ensink, J. M. (2008). "Penile and preputial tumours in the horse: A retrospective study ... Sarcoids are the most common type of skin neoplasm and are the most common type of cancer overall in horses. Squamous-cell ... Pony geldings and work horses are more prone to developing SCC on the penis, due to less frequent penile washing when compared ... Equine papillomavirus-2 has also been found within penile SCCs, but has not been determined to cause SCC. Before treatment of ...
... penile intraepithelial neoplasia); and on or around the anus, AIN (anal intraepithelial neoplasia). The terminology has been ... neoplasms, and cysts, Virus-related cutaneous conditions, Papillomavirus-associated diseases, All stub articles, Infection- ... related cutaneous condition stubs, Epidermal nevi, neoplasm, cyst stubs). ...
Penile cancer Vaginal cancer "Vulvar Cancer Treatment". National Cancer Institute. 9 April 2019. Retrieved 31 May 2019. "Cancer ... "Vulvar Cancer". Gynecologic Neoplasms. Armenian Health Network, Health.am. 2005. Retrieved 2007-11-08. Wohlmuth, Christoph; ...
... neoplasms, and cysts, Carcinoma, Infectious causes of cancer, Wikipedia medicine articles ready to translate, Papillomavirus- ... "Clinical and pathologic factors of prognostic significance in penile squamous cell carcinoma in a North American population". ...
A possible cause may be a neoplasm that originates from estrogen-secreting cells. Tumors that produce hCG stimulate production ... In adolescent males, it is recommended that surgery is postponed until puberty is completed (penile and testicular development ... evaluation of penile size and development, evaluation of testicular development and an assessment for masses that raise ...
In many cases, a variety of socio-economic interventions come in play to determine penile activity. For the Shona people, since ... Age group 12-49 (Paternal age effect) Aneuploidy, an abnormal number of chromosomes Centriole Neoplasm, e.g. seminoma ... The history should include prior testicular or penile insults (torsion, cryptorchidism, trauma), infections (mumps orchitis, ... impotence is linked to infertility, an examination to check on the penile function spans from infancy to post marriage. At ...
They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often ... It is used to treat basal cell skin cancer and the very early stages of others like cervical, penile, vaginal, vulvar, and non- ...
Approximately 96% of bicalutamide prescriptions were written for diagnosis codes that clearly indicated neoplasm. About 1,200, ... reduced penile length, and decreased semen/ejaculate volume, may occur in men. Other side effects that have been observed in ...
Pathology of Testicular and Penile Neoplasms. Springer. p. 184. ISBN 978-3-319-27617-5. Nieschlag, Eberhard & Behre, Hermann ( ...
Penile tumors present a difficult diagnostic and therapeutic issue, mainly because of their psychological implications. The ... Basaloid squamous cell carcinoma: a distinctive human papilloma virus-related penile neoplasm: a report of 20 cases. Am J Surg ... Penile SCC. Penile squamous cell carcinoma (SCC) is the cause of fewer than 1-2% of all deaths from cancer in men in the United ... Penile horn. Penile horn is a rare condition that usually appears as a hard and conical keratotic mass with a bulging ...
Genital neoplasms treated by en bloc resection and penile retroversion in horses: 10 cases (1977-1986). J Am Vet Med Assoc 1988 ... Genital neoplasms treated by en bloc resection and penile retroversion in horses: 10 cases (1977-1986). J Am Vet Med Assoc 1988 ... Genital neoplasms treated by en bloc resection and penile retroversion in horses: 10 cases (1977-1986). J Am Vet Med Assoc 1988 ... Genital neoplasms treated by en bloc resection and penile retroversion in horses: 10 cases (1977-1986). . J Am Vet Med Assoc. ...
Penile Neoplasms 1st International Congress on the History of Nursing Education (ICoHNE), 5th Colloquium of the Brazilian ...
Penile Neoplasms / prevention & control * Penile Neoplasms / virology * Registries * United States / epidemiology * Uterine ... of penile, 32.0% of oral cavity, and 20.9% of laryngeal cancers, as well as in 98.8% of cervical cancer in situ (CCIS). A ... as well as many penile (47.9%), vulvar (48.6%) cancers: 24 858 cases annually. The 9-valent vaccine also targeting HPV 31/33/45 ...
DaPeCa-4: outcome in penile cancer patients with N3 disease due to extra nodal extension treated with surgery and chemo- ...
Risk factors associated with the development of penile neoplasms Marcos Vitor Batista de Oliveira; Wygor Bruno e Silva Morais; ...
Penile cancer, Squamous cell carcinoma, Epidemiology, Penile diseases Introduction. Penile cancer is a rare neoplasm in the ... Independent prognostic factors for penile cancer are the stage of the neoplasm (favorable , T1), the volume of the lesion ( ... Since American and European studies describe penile cancer as a rare neoplasm. ... The predominant histologic types of penile cancer are penile squamous cell carcinoma (SCC), melanoma, lymphoma, sarcoma, and ...
keywords = "Carcinoma, Circumcision, Incidence, Male, Penile neoplasms, Squamous cell",. author = "James Sewell and Weranja ... Trends in penile cancer: a comparative study between Australia, England and Wales, and the US. SpringerPlus. 2015 Dec 18;4(1): ... Trends in penile cancer : a comparative study between Australia, England and Wales, and the US. In: SpringerPlus. 2015 ; Vol. 4 ... Trends in penile cancer: a comparative study between Australia, England and Wales, and the US. / Sewell, James; Ranasinghe, ...
Cord NeoplasmsVaginal NeoplasmsAdrenal Gland NeoplasmsNervous System NeoplasmsPenile NeoplasmsNeoplasm SeedingGenital Neoplasms ... Pancreatic NeoplasmsNeoplasmsLymphatic MetastasisSkin NeoplasmsNeoplasms, Cystic, Mucinous, and SerousLung NeoplasmsNeoplasms, ... Uterine NeoplasmsBreast NeoplasmsColonic NeoplasmsBone Marrow NeoplasmsEndocrine Gland NeoplasmsIntestinal NeoplasmsNeoplasms, ... NeoplasmsGastrointestinal NeoplasmsLymphomaParotid NeoplasmsOvarian NeoplasmsColorectal NeoplasmsNeoplasm MetastasisNeoplasm ...
Penile Neoplasms - Diagnosis, Penile Neoplasms - Mortality, Penile Neoplasms - Pathology, Penile Neoplasms/diagnosis/*mortality ... Penile Neoplasms - Diagnosis; Penile Neoplasms - Mortality; Penile Neoplasms - Pathology; Penile Neoplasms/diagnosis/*mortality ... The importance of extranodal extension in penile cancer: a meta-analysis.. Title. The importance of extranodal extension in ... BACKGROUND: The role of extranodal extension (ENE) in penile cancer is controversial and has not been well studied. The aim of ...
Human Papilloma Virus - presence and importance in penile cancer and treatment of penile cancer in situ. Kristiansen, S., ... Penile intraepithelial neoplasia, penile cancer precursors and human papillomavirus prevalence in symptomatic preputium: a ... Increased prevalence of human papillomavirus in fresh tissue from penile cancers compared to non-malignant penile samples: a ... Penile Neoplasms Medicine & Life Sciences 62% * Sternotomy Medicine & Life Sciences 41% * Sweden Medicine & Life Sciences 33% ...
Penile Neoplasms 38% * Urologic Neoplasms 38% * Aprotinin in the management of coagulopathy associated with amniotic fluid ...
Single-port robotic inguinal lymph node dissection: A safe and feasible option for penile cancer. Patel, A. S. & Isharwal, S., ...
Penile Neoplasms 38% * Urologic Neoplasms 38% * A Rare Case Report of An Adult with Rapidly Progressive Glomerulonephritis ...
Penile Neoplasms 22% 53 Scopus citations * Outcome of micropulse laser transscleral cyclophotocoagulation on pediatric versus ...
penile neoplasm DOID:11624 * type 1 papillary adenoma of the kidney DOID:6258 ...
Label: childhood kidney neoplasm Synonyms: childhood kidney neoplasm Alternative IDs: als API: GO ...
Penile Neoplasms Medicine & Life Sciences 31% * Neoplasms Medicine & Life Sciences 10% * Formaldehyde Medicine & Life Sciences ... Detection and typing of human papillomavirus DNA in penile carcinoma: Evidence for multiple independent pathways of penile ... Detection and typing of human papillomavirus DNA in penile carcinoma: Evidence for multiple independent pathways of penile ... Detection and typing of human papillomavirus DNA in penile carcinoma: Evidence for multiple independent pathways of penile ...
Pathology of testicular and penile neoplasms Published 2016 Call Number: Loading.... Located: Loading... ... 1 Penile induration. 1 Penile prostheses. 1 Psychological aspects. 1 Sex. 1 Sex (Psychology). 1 Sex customs. 1 Sexual behavior ...
Penile Neoplasms * Precancerous Conditions * Carcinoma in Situ * Penis Explore _. Co-Authors (24) ...
Background and Objectives: Penile cancer is a rare neoplasm in developed countries with an incidence of 0.8/100,000 per male ... Results: We observed higher expression of pro-inflammatory cytokine genes (IL-1A, IL-1B, IL-6, INF-γ, TGF-ß) in penile cancer ... Pro-Inflammatory Cytokine Gene Expression in Penile Cancer: Preliminary Studies. Czajkowski, Mateusz; Wierzbicki, Piotr M; ... The average follow-up period was 48 months (range: 38-54 months), during which only one penile tumor progression was observed ...
... should be included in the differential diagnosis of penile neoplasm. Surgical excision of the lesion provides both the ...
Penile tumors present a difficult diagnostic and therapeutic issue, mainly because of their psychological implications. The ... Basaloid squamous cell carcinoma: a distinctive human papilloma virus-related penile neoplasm: a report of 20 cases. Am J Surg ... Penile SCC. Penile squamous cell carcinoma (SCC) is the cause of fewer than 1-2% of all deaths from cancer in men in the United ... Penile horn. Penile horn is a rare condition that usually appears as a hard and conical keratotic mass with a bulging ...
Uncircumcised men and those with HPV infections are at highest risk of penile neoplasms. Diagnosis is a combination of physical ... Penile Cancer Malignant lesions of the penis arise from the squamous epithelium of the glans, prepuce, or penile shaft. Penile ... Penile Anomalies and Conditions Penile anomalies and conditions may be congenital or acquired and can affect the urethral ... Invasive surgical penile implants may be considered when conservative measures fail. Ultimately, both the patient and partner ...
Liver neoplasms KW - Nasopharyngeal neoplasms KW - Penile neoplasms KW - Sarcoma, Kaposis KW - Africa N1 - Proceedings of a ... Uterine cervical neoplasms KW - Hepatitis B virus KW - pathogenicity KW - Leukemia KW - ...
... the surgical excision and reconstruction of multiple penile syringomas are described. ... Syringomas are thought to be benign neoplasms of eccrine gland origin.[1] Friedman and Butler[2] proposed a classification ... Objective: Penile syringomas are rare lesions usually occurring in isolation. We report the excision and reconstruction of ... Methods: We report a rare case of excision of multiple penile syringomas and reconstruction with scrotal flaps in a 29-year-old ...
Diffuse large B-cell lymphoma is the most common primary penile lymphoma. (WHO 2016) ... A lymphoma that arises from penile skin, subcutis, corpora cavernosa, and spongiosum. ... Primary penile lymphoma presenting as a penile ulcer.. Fairfax CA, Hammer CJ 3rd, Dana BW, Hanifin JM, Barry JM. J Urol 1995 ... Penile metastasis secondary to nasal NK/T-cell lymphoma.. Lan SK, Lin CW, Ho HC, Lee MS, Tzeng JE, Su YC. Urology 2008 Nov;72(5 ...
  • They are also defined as penile intraepithelial neoplasia, whereas the abbreviation Tis is used in the tumor-node-metastasis (TNM) classification. (medscape.com)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
  • The aim of this study was to investigate the importance of ENE in predicting prognosis and presence of pelvic lymph node metastasis (PLNM) in penile cancer patients. (omeka.net)
  • Among malignant neoplasms of the penis, squamous cell carcinoma (SCC) is the most common. (medscape.com)
  • The cause of penile squamous cell carcinoma (SCC) is unclear, although human papillomavirus (HPV) appears to play a major role in many cases. (medscape.com)
  • To clarify the role of human papillomavirus (HPV) in penile cancer we evaluated the prevalence of HPV DNA in different histological subtypes of penile carcinoma, dysplasia, and condyloma using a novel, sensitive SPF10 HPV polymerase chain reaction assay and a novel genotyping line probe assay, allowing simultaneous identification of 25 different HPV types. (elsevierpure.com)
  • HPV DNA was detected in 42% cases of penile carcinoma, 90% cases of dysplasia, and 100% cases of condyloma. (elsevierpure.com)
  • Surgical Approach to a Penile cancer, squamous cell carcinoma, erythroplasia of Queyrat. (bvsalud.org)
  • El estudio histopatológico reportó un carcinoma escamoso invasor en la lesión del prepucio y en la piel del glande, con todos los márgenes quirúrgicos, limites laterales y profundos, negativos a malignidad. (bvsalud.org)
  • Conclusion Regardless of tumor subtypes, penile carcinoma in Northeastern Brazil had more aggressive features and behavior when presented at younger age. (fiocruz.br)
  • In 1948, Lauren V. Ackermann first described this neoplasm of the oral mucous membrane, which is now also know as Verrucous Carcinoma of Ackermann or Ackermann's tumor. (ispub.com)
  • Whether the carcinoma occur in the upper aerodigestive tract (verrucous carcinoma), on the genitalia (condyloma acuminatum), or on extremities (carcinoma cuniculatum), they are essentially the same neoplasm with slow growing, locally invasive and nonmetastasizing behavior 3 . (ispub.com)
  • Patients who did not undergo full colonoscopy preoperatively should undergo colonoscopy within 3-6 months postoperatively to exclude other synchronous colorectal neoplasms and 1 year thereafter. (health.am)
  • HPV DNA was detected in 90.6% of cervical, 91.1% of anal, 75.0% of vaginal, 70.1% of oropharyngeal, 68.8% of vulvar, 63.3% of penile, 32.0% of oral cavity, and 20.9% of laryngeal cancers, as well as in 98.8% of cervical cancer in situ (CCIS). (nih.gov)
  • To trace the clinical and epidemiological profile of penile cancer in Rio Grande do Norte/Brazil and relate them to data published in the literature. (clinmedjournals.org)
  • A retrospective cohort study was conducted with 94 patients diagnosed with penile cancer in 2011-2018, treated at the Liga Norte Riograndense Contra o Cancer. (clinmedjournals.org)
  • The State of Rio Grande do Norte has a high incidence of penile cancer with a high frequency of locally advanced tumors at diagnosis and in younger patients younger than 50. (clinmedjournals.org)
  • Penile cancer is a rare neoplasm in the United States and Europe, accounting for less than 1% of cancers in men. (clinmedjournals.org)
  • Brazil is one of the countries with the highest incidence of penile cancer in the world [ 5 , 6 ] which may correspond to 2.1% of all neoplasms in men, being five times more prevalent in the North and Northeast regions [ 7 ], where most of the procedures are performed. (clinmedjournals.org)
  • Among these regions, Brazilian studies indicate that the State of Maranhão (Northeast of Brazil) has the highest incidence of penile cancer in Brazil, with an age-standardized incidence of 6.15 cases/100,000 habitants, with approximate statistics of one new case every 17 days [ 6 ]. (clinmedjournals.org)
  • Penile cancer is an aggressive and mutilating disease that affects self-esteem, with psychological and functional repercussions, which make rehabilitation and social reintegration difficult [ 7 ]. (clinmedjournals.org)
  • Therefore, the Brazilian Penile Cancer Consensus argues that reducing the incidence of this cancer is possible by encouraging intimate hygiene education, neonatal circumcision, smoking cessation, vaccination against HPV among young people, and the use of condoms [ 4 ]. (clinmedjournals.org)
  • Purpose: To investigate and compare the trends in incidence and mortality of penile cancer between Australia, England and Wales, and the US, and provide hypotheses for these trends. (ukhsa.gov.uk)
  • Results: The overall incidence of penile cancer in England and Wales (1.44 per 100,000 man-years) was higher than in Australia (0.80 per 100,000), and the US (0.66 per 100,000). (ukhsa.gov.uk)
  • Incidence of penile cancer in all three countries has remained relatively stable over time. (ukhsa.gov.uk)
  • Conclusions: Penile cancer incidence is low, affecting mainly older men. (ukhsa.gov.uk)
  • The importance of extranodal extension in penile cancer: a meta-analysis. (omeka.net)
  • BACKGROUND: The role of extranodal extension (ENE) in penile cancer is controversial and has not been well studied. (omeka.net)
  • Further subgroup analysis revealed that the predictive value of ENE for CSS in penile cancer patients was significant regardless of the study's country of origin, but not in the subgroup with shorter follow-up time (\textless36 months, P = 0.38). (omeka.net)
  • CONCLUSIONS: ENE is associated with worse prognosis and high risk of PLNM in penile cancer patients. (omeka.net)
  • Zhou Fang-Jian, "The importance of extranodal extension in penile cancer: a meta-analysis. (omeka.net)
  • In addition, specific histological subtypes of penile cancer - basaloid and warty - are consistently associated with HPV, however, only a subset of keratinizing and verrucous penile carcinomas is positive for HPV DNA, and thus these two tumor groups seem to develop along different pathogenetic pathways. (elsevierpure.com)
  • Penile cancer: a local case series and literature review. (nih.gov)
  • Paiva GR Penile cancer. (fiocruz.br)
  • Purpose In order to describe epidemiological and pathological features of penile cancer in a high-risk area of Brazil. (fiocruz.br)
  • Methods We reviewed the experience (378 patients from 1997 to 2007) of Hospital Aristides Maltez from Salvador, Bahia-the main institution in the state which provides oncologic treatment for penile cancer in the public health system. (fiocruz.br)
  • Penile cancer risks can be increased by a number of causes such as smoking, phimosis, poor hygiene, multiple sexual partners and history of gential warts or other sexually transmitted diseases. (uk.com)
  • This year the congress will be broadcast online, and will present modules such as Kidney, Prostate, Penile and Bladder Cancer, bringing important national and international experts to discuss relevant topics in these areas. (lacogcancerresearch.org)
  • Cancer uterine icd 10 ICDCM BootCamp: Neoplasms retete pt detoxifiere Un vierme mic costache ioanid smoothie verde detoxifiant retete, rectal cancer x ray toxine botulique rat. (wishstudio.ro)
  • ICD - 10 Guidelines - Chapter 2 Neoplasms C00 D49 - class 1 - Medical Coding Guidelines enemas de la viermi la copii Papiloma virus cancer garganta preparate pentru tratarea helmintelor umane, endometrial cancer icd 10 papilloma gola ciuperci de plop. (wishstudio.ro)
  • Medical Coding of Neoplasms: Part 1 rectal cancer uk statistics Definition for toxine rectal cancer journal articles, squamous vestibular papillomatosis cancerul pancreasului endocrin. (wishstudio.ro)
  • ICDCM Coding Demonstration using Neoplasm Table cancerul gastric-intestinal Profilaxie helminti case laryngeal papilloma, papillomavirus homme oeil kako se leci hpv Condylomata acuminata definition hpv cervical cancer leep, papilloma virus e ciclo mestruale papilloma squamous eyelid. (wishstudio.ro)
  • Kirrander P, Sherif A, Friedrich B, Lambe M, Hakansson U, steering committee of the Swedish National Penile Cancer R. The Swedish National Penile Cancer Register: Incidence, Tumour Characteristics, Management and Survival. (cancercentrum.se)
  • A vaccine targeting HPV 16/18 potentially prevents the majority of invasive cervical (66.2%), anal (79.4%), oropharyngeal (60.2%), and vaginal (55.1%) cancers, as well as many penile (47.9%), vulvar (48.6%) cancers: 24 858 cases annually. (nih.gov)
  • A systematic review by Ribera-Cortada et al in 2021 noted that the most common mutations in cases of penile SCC involved the genes TP53 , CDKN2A , FAT1 , NOTCH-1 , and PIK3CA . (medscape.com)
  • SCC of the prostate is a rare malignant epithelial neoplasm arising in the prostate, with squamous differentiation of the neoplastic cells. (medscape.com)
  • This rare pathologic finding, which usually mimics a malignant lesion, should be included in the differential diagnosis of penile neoplasm. (edu.pl)
  • In 1896, Buschke, and subsequently in 1925, Buschke and Loewenstein, described a penile lesion which appeared benign cytologically, yet which behaved in a malignant fashion. (ispub.com)
  • Ureteral Neoplasms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • This graph shows the total number of publications written about "Ureteral Neoplasms" by people in UAMS Profiles by year, and whether "Ureteral Neoplasms" was a major or minor topic of these publications. (uams.edu)
  • Below are the most recent publications written about "Ureteral Neoplasms" by people in Profiles over the past ten years. (uams.edu)
  • Penile tumors present a difficult diagnostic and therapeutic issue, mainly because of their psychological implications. (medscape.com)
  • We report the excision and reconstruction of multiple synchronous penile shaft syringomas with local scrotal flaps. (medscape.com)
  • We report a rare case of excision of multiple penile syringomas and reconstruction with scrotal flaps in a 29-year-old man. (medscape.com)
  • All types of hematologic neoplasms have been previously reported, although CML has been rarely encountered. (amjcaserep.com)
  • Kaposi sarcoma is a vascular neoplasm composed of endothelium-lined vascular spaces and spindle-shaped cells. (bvsalud.org)
  • Kaposi's sarcoma is a neoplasm of vascular endothelium that is characterized by proliferation of spindle cells, neoangiogenesis, inflammation and edema 17 . (bvsalud.org)
  • Local penile factors and systemic diseases, including diabetes, cardiac disease, and neurologic disorders, can cause ED. Diagnosis is via physical exam and history. (lecturio.com)
  • There was evident dysgranulopoiesis that raised a provisional diagnosis of myelodysplastic/myeloproliferative neoplasm. (amjcaserep.com)
  • Annually, the scientific program is developed with the most actual in the treatment and diagnosis of genitourinary neoplasms. (lacogcancerresearch.org)
  • The treatment of penile SCC varies according to the clinical stage. (medscape.com)
  • Invasive surgical penile implants may be considered when conservative measures fail. (lecturio.com)
  • Ki-67 assessment of pancreatic neuroendocrine neoplasms: Systematic review and meta-analysis of manual vs. digital pathology scoring. (who.int)
  • Despite being a complex surgery, studies show that penile reconstruction (phalloplasty) is possible after penectomy when the functional length of the Penis is inadequate for a man to urinate standing up or have sexual intercourse [ 8 - 10 ]. (clinmedjournals.org)
  • An isolated penile mass in a young adult turned out to be a primary marginal zone lymphoma of the penis. (nih.gov)
  • A 64-year-old male patient presented with a soft, cystic, large subcutaneous mass on the right ventral side of the penis, located in the distal half of the penile shaft, causing distortion, with no underlying disease. (jwmr.org)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • Kim et al found mutations of TERT-p in 18 out of 37 (48.6%) penile SCCs, including all 3 of the in situ cases. (medscape.com)
  • Diffuse large B-cell lymphoma is the most common primary penile lymphoma. (nih.gov)
  • Primary penile lymphoma: the use of PET-CT for accurate staging and response monitoring. (nih.gov)
  • Primary penile lymphoma: diagnostic difficulties and management options. (nih.gov)
  • Primary penile lymphoma presenting as a penile ulcer. (nih.gov)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • Other associations considered to play a role in the development of penile SCC include pre-existing dermatoses, lack of circumcision, and other factors, including environmental exposures. (medscape.com)
  • A A 52-year-old male patient presented to the urology office with a two-year history of noticing a Abordaje quirúrgico bright red, pruritic, and painful lesion on the glans and foreskin with a progressive increase in size that did not improve with primario en un paciente antibiotic and antifungal treatments. (bvsalud.org)
  • The authors also noted that Hippo, Notch, and RTK-RAS pathways are often deregulated in penile SCC patients. (medscape.com)
  • Penile squamous cell carcinoma (PSCC) is rare with limited treatment options. (nih.gov)
  • 6. Limitations in the interpretation of biopsies in patients with penile squamous cell carcinoma. (nih.gov)
  • Among malignant neoplasms of the penis, squamous cell carcinoma (SCC) is the most common. (medscape.com)
  • The cause of penile squamous cell carcinoma (SCC) is unclear, although human papillomavirus (HPV) appears to play a major role in many cases. (medscape.com)
  • Development of a new outcome prediction model for Chinese patients with penile squamous cell carcinoma based on preoperative serum C-reactive protein, body. (oncotarget.com)
  • Purpose: To determine the predictive value and feasibility of the new outcome prediction model for Chinese patients with penile squamous cell carcinoma. (oncotarget.com)
  • Basaloid and warty subtypes of penile squamous cell carcinoma are most frequently associated with HPV infection. (chennaicircumcisionclinic.in)
  • Surgical Approach to a Penile cancer, squamous cell carcinoma, erythroplasia of Queyrat. (bvsalud.org)
  • A clinical suspicion of an invasive squamous cell carcinoma was made and the patient underwent a wide local excision of the penile and satellite lesions. (biomedcentral.com)
  • 12. Sarcomatoid Carcinoma of the Penis: An Uncommon Penile Neoplasm. (nih.gov)
  • Radiation Induced Multiple Skin Neoplasms Following Craniospinal Irradiation for Medulloblastoma. (amjcaserep.com)
  • Neoplasms, Connective Tissue" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (jefferson.edu)
  • The concept does not refer to neoplasms located in connective tissue. (jefferson.edu)
  • This graph shows the total number of publications written about "Neoplasms, Connective Tissue" by people in this website by year, and whether "Neoplasms, Connective Tissue" was a major or minor topic of these publications. (jefferson.edu)
  • Below are the most recent publications written about "Neoplasms, Connective Tissue" by people in Profiles. (jefferson.edu)
  • SCC of the prostate is a rare malignant epithelial neoplasm arising in the prostate, with squamous differentiation of the neoplastic cells. (medscape.com)
  • An extremely rare penile epithelial neoplasm, histologically composed of nests of epithelial cells floating in lakes of extracellular, PAS-positive mucin, with clinical characteristics of a nonhealing ulcer or soft mass in the preputium or glans area, with itching and burning often preceding appearance of the lesion. (cdc.gov)
  • Objectives: To analyse the incidence, treatment strategies and complications associated with penile intraepithelial neoplasia (PeIN) in Sweden over a period of 20 years. (lu.se)
  • Recurrent inflammation of the prenuptial skin linked to penile malignancies is attributed to the presence of phimosis. (chennaicircumcisionclinic.in)
  • Zeiger, Roni F.. "Penile Papules & Other Lesions. (unboundmedicine.com)
  • Medicine Central , im.unboundmedicine.com/medicine/view/Diagnosaurus/115000/all/Penile_papules_&_other_lesions. (unboundmedicine.com)
  • Phimosis being a structural inability of a tight foreskin that cannot be retracted, when left untreated can lead to secondary complications that increase the susceptibility for penile carcinoma. (chennaicircumcisionclinic.in)
  • A A 52-year-old male patient presented to the urology office with a two-year history of noticing a Abordaje quirúrgico bright red, pruritic, and painful lesion on the glans and foreskin with a progressive increase in size that did not improve with primario en un paciente antibiotic and antifungal treatments. (bvsalud.org)
  • Other associations considered to play a role in the development of penile SCC include pre-existing dermatoses, lack of circumcision, and other factors, including environmental exposures. (medscape.com)
  • Whole-body computed tomography (CT) scan often reveals disseminated neoplastic disease, which is the cause of high mortality in secondary penile neoplasms. (bvsalud.org)
  • We determined whether SWE values are correlated with the degree of penile curvature, the time of disease onset, and pain severity experienced by patients during erection. (researchgate.net)
  • An 87-year-old Caucasian male was referred to our centre by a dermatologist, having undergone punch biopsy of a penile lesion with the initial histology reported as showing Bowen's disease. (biomedcentral.com)
  • Kim et al found mutations of TERT-p in 18 out of 37 (48.6%) penile SCCs, including all 3 of the in situ cases. (medscape.com)
  • PSCC and matched normal penile tissues from 34 prospectively followed patients, underwent genomic WES and human papilloma virus testing. (nih.gov)
  • It is both a physically and psychologically devastating disorder that causes penile deformity, curvature, narrowing and shortening, which eventually compromise sexual function. (researchgate.net)
  • We also review the literature and highlight the need for a high index of suspicion in the diagnosis of this rare neoplasm. (biomedcentral.com)
  • The authors also noted that Hippo, Notch, and RTK-RAS pathways are often deregulated in penile SCC patients. (medscape.com)