Phlebitis
Cephapirin
Solanaceous Alkaloids
Matricaria
Menogaril
Catheterization, Peripheral
Colitis, Ischemic
Nogalamycin
Emulsions
Fatty Acids, Nonesterified
Lipoprotein-X
Propofol
Health Personnel
Experimental infusion phlebitis: tolerance pH of peripheral vein. (1/82)
This study aims to determine the pH that peripheral veins can tolerate. Intravenous nutrient solutions with different pHs (from 4.52 to 6.71) were infused into rabbit ear veins, and the veins were examined histopathologically. After 6-hr infusion at 10 mL/kg/hr, a commercial 2.72% amino acid/7.5% glucose solution with electrolytes (AG) caused obvious phlebitic changes, such as loss of venous endothelial cells, inflammatory cell infiltration, and perivascular edema, in all 6 rabbits because of its low pH (4.52) and high titratable acidity (22 mEq/L). The phlebitis was reduced when the solution was neutralized with NaOH to pH 5.93, and was almost eliminated when the pH was neutralized to 6.49. After 8-hr infusion at 15 mL/kg/hr, AG-adjusted pH to 6.30 caused slight phlebitic changes, but AG-adjusted pH to 6.71 scarcely caused any change. Furthermore, 24-hr infusion of the pH 6.49 solution caused no histopathological changes in 3 rabbits. These results suggest that the tolerance pH for the peripheral vein is about 6.5, and that an infusion solution does not cause phlebitis due to acidity if the pH is not lower than the tolerance pH. (+info)Tortuous, engorged pial veins in intracranial dural arteriovenous fistulas: correlations with presentation, location, and MR findings in 122 patients. (2/82)
BACKGROUND AND PURPOSE: Tortuous, engorged veins can be identified on the venous phase of the brain circulation in patients with venous congestion related to an intracranial dural arteriovenous fistula (DAVF). The term pseudophlebitic pattern (PPP) has been used to describe this finding. The purpose of this study was to determine the prevalence of PPP in patients with intracranial DAVF and to analyze the relationship of this sign to presentation, location of the fistula, presence of retrograde leptomeningeal venous drainage, and MR findings. METHODS: We retrospectively reviewed the charts and imaging findings of 130 patients with intracranial DAVF. In 122 patients the venous phase of the brain circulation was adequately assessed. The PPP was graded as mild, moderate, or severe. RESULTS: PPP was found in 51 patients (42%). Thirty-two (73%) of the 44 patients who had a hemorrhage, neurologic deficit, or seizure had PPP as compared with 16 (21%) of the 75 who had a bruit or orbital signs. The three patients with either congestive heart failure or increasing head circumference had PPP. Fourteen (88%) of the 16 who had fistula of the superior sagittal sinus, straight sinus, or superior petrosal sinus had PPP. PPP was seen in 46 (81%) of 57 patients who had retrograde leptomeningeal venous drainage and in five (8%) of the 65 who had only sinosal drainage. Fourteen (88%) of the 16 who had white matter T2 hyperintensity on MR images had severe PPP. CONCLUSION: The PPP reflects venous congestion and is associated with an aggressive presentation with or without retrograde leptomeningeal venous drainage. PPP may be a useful prognostic indicator and should be considered in treatment decisions. (+info)Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. (3/82)
Interleukin-6 (IL-6) is a pleiotropic cytokine, whose plasma levels are elevated in inflammatory diseases such as atherosclerosis. We have previously reported that peroxisome proliferator-activated receptor alpha (PPARalpha) ligands (fibrates) lower elevated plasma concentrations of IL-6 in patients with atherosclerosis and inhibit IL-1-stimulated IL-6 secretion by human aortic smooth muscle cells (SMC). Here, we show that aortic explants isolated from PPARalpha-null mice display an exacerbated response to inflammatory stimuli, such as lipopolysaccharide (LPS), as demonstrated by increased IL-6 secretion. Furthermore, fibrate treatment represses IL-6 mRNA levels in LPS-stimulated aortas of PPARalpha wild-type, but not of PPARalpha-null mice, demonstrating a role for PPARalpha in this fibrate action. In human aortic SMC, fibrates inhibit IL-1-induced IL-6 gene expression. Furthermore, activation of PPARalpha represses both c-Jun- and p65-induced transcription of the human IL-6 promoter. Transcriptional interference between PPARalpha and both c-Jun and p65 occurs reciprocally, since c-Jun and p65 also inhibit PPARalpha-mediated activation of a PPAR response element-driven promoter. This transcriptional interference occurs independent of the promoter context as demonstrated by cotransfection experiments using PPARalpha, p65, and c-Jun Gal4 chimeras. Overexpression of the transcriptional coactivator cAMP-responsive element-binding protein-binding protein (CBP) does not relieve PPARalpha-mediated transcriptional repression of p65 and c-Jun. Finally, glutathione S-transferase pull-down experiments demonstrate that PPARalpha physically interacts with c-Jun, p65, and CBP. Altogether these data indicate that fibrates inhibit the vascular inflammatory response via PPARalpha by interfering with the NF-kappaB and AP-1 transactivation capacity involving direct protein-protein interaction with p65 and c-Jun. (+info)Polymerase chain reaction for detection of Mycobacterium tuberculosis in epiretinal membrane in Eales' disease. (4/82)
PURPOSE: Tuberculous etiology has been suggested in Eales' disease. Because epiretinal membrane (ERM) is formed on the inner surface of the retina in Eales' disease, it could be the most appropriate intraocular specimen for investigation. Therefore, a nested polymerase chain reaction (nPCR), which detects MPB64 gene of Mycobacterium tuberculosis on the archival specimens of ERM of well-documented Eales' and non-Eales' patients, was applied and the results compared. METHODS: nPCR technique was standardized, and the sensitivity and specificity of the primers were determined. nPCR technique was applied to tissue sections obtained from formalin-fixed and paraffin-embedded tissues of ERM from 23 patients with Eales' disease and 27 noninfective and non-Eales' disease patients as controls. RESULTS: nPCR technique was specific for M. tuberculosis genome and sensitive enough to detect 0.25 fg (corresponding to the presence of a single bacillus). Eleven (47.8%) ERM of 23 Eales' disease and 3 (11.1%) of 27 controls were positive for M. tuberculosis genome. The difference between the two groups was statistically significant (P = 0.001), indicating association of this bacterium with Eales' disease. CONCLUSIONS: The demonstration of the presence of M. tuberculosis DNA by nPCR technique in significant number of ERM of Eales' disease compared with the controls further emphasizes the probable role of this bacterium in the pathogenesis of this enigmatic clinical condition. (+info)Lengthening the greater saphenous vein with the use of the lateral femoral cutaneous vein. (5/82)
Besides quality, the length of the greater saphenous vein dictates the feasibility of vein bypass grafts in femorodistal popliteal or tibial revascularization. A simple and effective technique of lengthening the greater saphenous vein is described that allows the use of the laterofemoral cutaneous vein in continuity. This technique can be applied when the distal segment of the greater saphenous vein is inadequate or unavailable. (+info)Tirilazad mesylate in acute ischemic stroke: A systematic review. Tirilazad International Steering Committee. (6/82)
BACKGROUND AND PURPOSE: Tirilazad is a nonglucocorticoid, 21-aminosteroid that inhibits lipid peroxidation. Studies in experimental models of ischemic stroke had suggested that tirilazad had neuroprotective properties. As a result, clinical studies were undertaken to assess the safety and efficacy of tirilazad in the treatment of acute ischemic stroke. We performed a systematic review of randomized, controlled trials that assessed the safety and efficacy of tirilazad in patients with acute ischemic stroke. METHODS: Trials of tirilazad were identified from searches of the Cochrane Library and communication with the Pharmacia & Upjohn company, the manufacturer of tirilazad. Data relating to early and end-of-trial case fatality, disability (Barthel Index and Glasgow Outcome Scale), phlebitis, and corrected QT interval were extracted by treatment group from published data and company reports and analyzed by using the Cochrane Collaboration meta-analysis software REVMAN. RESULTS: Six trials (4 published, 2 unpublished) assessing tirilazad in 1757 patients with presumed acute ischemic stroke were identified; all were double-blind and placebo controlled in design. Tirilazad did not alter early case fatality (odds ratio [OR] 1.11, 95% confidence interval [CI] 0.79 to 1.56) or end-of-trial case fatality (OR 1.12, 95% CI 0.88 to 1.44). A just-significant increase in death and disability, assessed as either the expanded Barthel Index (OR 1.23, 95% CI 1.01 to 1.51) or Glasgow Outcome Scale (OR 1. 23, 95% CI 1.01 to 1.50) was observed. Tirilazad significantly increased the rate of infusion site phlebitis (OR 2.81, 95% CI 2.14 to 3.69). Functional outcome (expanded Barthel Index) was significantly worse in prespecified subgroups of patients: females (OR 1.46, 95% CI 1.08 to 1.98) and subjects receiving low-dose tirilazad (OR 1.31, 95% CI 1.03 to 1.67); a nonsignificant worse outcome was also seen in patients with mild to moderate stroke (OR 1. 40, 95% CI 0.99 to 1.98). CONCLUSIONS: Tirilazad mesylate increases death and disability by about one fifth when given to patients with acute ischemic stroke. Although further trials of tirilazad are now unwarranted, analysis of individual patient data from the trials may help elucidate why tirilazad appears to worsen outcome in acute ischemic stroke. (+info)A phase II trial of bryostatin 1 in patients with non-Hodgkin's lymphoma. (7/82)
Bryostatin 1 is a naturally occurring macrocyclic lactone with promising antitumour and immunomodulatory function in preclinical and phase I clinical investigations. In this phase II study, 17 patients with progressive non-Hodgkin's lymphoma of indolent type (NHL), previously treated with chemotherapy, received a median of 6 (range 1-9) intravenous infusions of 25 microg/m(2) bryostatin 1 given once weekly over 24 hours. In 14 evaluable patients no responses were seen. Stable disease was attained in one patient for 9 months. The principal toxicities were myalgia and phlebitis. Treatment was discontinued early because of toxicity alone (phlebitis) in 2 patients, toxicity in addition to progressive disease in 3 patients (myalgia and phlebitis n = 2; thrombocytopenia n = 1) and progressive disease in 5 patients. The results fail to demonstrate efficacy of this regimen of bryostatin 1 in the treatment of NHL. In light of preclinical data that demonstrate synergy between bryostatin 1 and several cytotoxic agents and cytokines, clinical studies to investigate bryostatin 1 in combination are warranted. We also present data to demonstrate that central venous lines may be used in future studies to avoid phlebitis. (+info)A comparative analysis of warfarin and low-dose heparin as thromboembolism prophylaxis in total hip replacement patinets. (8/82)
Warfarin, low-dose heparin, or a combination of low-dose heparin and hydrocortisone was administered to 300 patients undergoing total hip replacement. The lowest incidence of thromboembolic (5 per cent) was attained with Warfarin. Further investigation into the method of administration of low-dose heparin is necessary before it can be used effectively as thromboembolism prophylaxis in total hip replacement patients. The addition of hydrocortisone was not found useful. (+info)Phlebitis is a medical term that refers to the inflammation of a vein, usually occurring in the legs. The inflammation can be caused by blood clots (thrombophlebitis) or other conditions that cause irritation and swelling in the vein's lining. Symptoms may include redness, warmth, pain, and swelling in the affected area. In some cases, phlebitis may lead to serious complications such as deep vein thrombosis (DVT) or pulmonary embolism (PE), so it is essential to seek medical attention if you suspect you have this condition.
Cephapirin is a type of antibiotic that belongs to the class of cephalosporins. It is used to treat various bacterial infections, including respiratory tract infections, skin and soft tissue infections, bone and joint infections, and genitourinary tract infections. Cephapirin works by interfering with the bacteria's ability to form a cell wall, which results in bacterial death.
Like other cephalosporins, cephapirin is generally well-tolerated and has a broad spectrum of activity against many different types of bacteria. However, it may cause side effects such as nausea, diarrhea, vomiting, and allergic reactions in some people. It is important to take cephapirin exactly as directed by a healthcare provider, and to complete the full course of treatment even if symptoms improve before all of the medication has been taken.
It's worth noting that Cephapirin is not a commonly used antibiotic now a days, due to the availability of other cephalosporins which are more effective and have less side effects.
Cephalothin is a type of antibiotic known as a first-generation cephalosporin. It is used to treat a variety of bacterial infections, including respiratory tract infections, skin and soft tissue infections, bone and joint infections, and urinary tract infections.
Cephalothin works by interfering with the ability of bacteria to form cell walls, which are essential for their survival. It binds to specific proteins in the bacterial cell wall, causing the wall to become unstable and ultimately leading to the death of the bacterium.
Like other antibiotics, cephalothin is only effective against certain types of bacteria, and it should be used under the direction of a healthcare professional. It is important to take the full course of treatment as directed, even if symptoms improve, to ensure that the infection is fully treated and to reduce the risk of developing antibiotic resistance.
Common side effects of cephalothin include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. More serious side effects may include allergic reactions, kidney damage, and seizures. It is important to inform your healthcare provider of any medical conditions you have or medications you are taking before starting treatment with cephalothin.
Solanaceous alkaloids are a type of natural toxin found in plants belonging to the Solanaceae family, also known as the nightshade family. These alkaloids contain nitrogen and are produced by the plant as a defense mechanism against herbivores and other threats. Some common solanaceous alkaloids include nicotine, atropine, scopolamine, and solanine.
Nicotine is found in tobacco plants (Nicotiana tabacum) and is highly addictive. Atropine and scopolamine are found in belladonna (Atropa belladonna), also known as deadly nightshade, and are used in medical settings for their anticholinergic effects, but can be toxic or even fatal if ingested in large quantities. Solanine is found in potatoes, tomatoes, and eggplants, and can cause gastrointestinal symptoms such as nausea, vomiting, and diarrhea if consumed in large amounts.
It's worth noting that the levels of solanaceous alkaloids in commonly consumed plants like potatoes and tomatoes are generally low and not considered harmful to most people. However, some individuals may be more sensitive to these compounds and may experience adverse effects even at low levels.
"Matricaria" is a genus of plants in the family Asteraceae, also known as the daisy family. The most common species is Matricaria chamomilla, which is commonly known as chamomile. This plant is native to Europe and Western Asia, and it has been used in traditional medicine for centuries due to its anti-inflammatory, antispasmodic, and calming properties.
The medicinal properties of Matricaria are primarily attributed to its volatile oils, flavonoids, and other chemical constituents found in the flowers and leaves of the plant. Chamomile tea is a popular herbal remedy made from the dried flowers of Matricaria chamomilla, which is often used to promote relaxation, improve sleep quality, and soothe digestive upset.
It's worth noting that while chamomile has been used safely in traditional medicine for many years, it can cause allergic reactions in some people, particularly those with allergies to other members of the Asteraceae family (such as ragweed or daisies). It's always a good idea to consult with a healthcare provider before starting any new herbal remedy.
Flucloxacillin is not strictly a medical "definition," but rather it is an antibiotic medication used to treat infections caused by susceptible gram-positive bacteria, such as Staphylococcus aureus, including methicillin-sensitive strains. It is a semisynthetic penicillin derivative that is resistant to degradation by beta-lactamases produced by many bacteria, making it effective against some bacteria that are resistant to other penicillins.
Flucloxacillin works by inhibiting the synthesis of bacterial cell walls, leading to bacterial death. It is often used to treat skin and soft tissue infections, bone and joint infections, and endocarditis caused by susceptible organisms. Like other antibiotics, flucloxacillin should be used judiciously to prevent the development of antimicrobial resistance.
It's important to note that the use of any medication, including flucloxacillin, should be under the guidance and supervision of a healthcare professional, who can consider the individual patient's medical history, current medications, and other factors to determine the most appropriate treatment.
I'm sorry for any confusion, but "Menogaril" does not appear to have a widely recognized or established medical definition. It is possible that you may be referring to a specific chemical compound or experimental drug. However, without more context or information, it is difficult for me to provide a precise definition.
Menogaril is a synthetic compound that has been studied in preclinical trials for its potential anticancer properties. It is an analog of the natural product dictyostatin and has been shown to inhibit the activity of several enzymes involved in DNA replication and repair, including topoisomerase II and poly(ADP-ribose) polymerase (PARP). However, it is important to note that Menogaril is not currently approved for use in clinical medicine, and its safety and efficacy have not been established in human trials.
Peripheral catheterization is a medical procedure that involves the insertion of a thin, flexible tube (catheter) into a peripheral vein, which is a blood vessel located outside of the chest and abdomen. This type of catheterization is typically performed to administer medications, fluids, or nutritional support, or to monitor various physiological parameters such as central venous pressure.
Peripheral catheters are usually inserted into veins in the hands or arms, although they can also be placed in other peripheral veins. The procedure is typically performed using aseptic technique to minimize the risk of infection. Once the catheter is in place, it may be secured with a dressing or suture to prevent movement and dislodgement.
Peripheral catheterization is a relatively safe and common procedure that is routinely performed in hospitals, clinics, and other healthcare settings. However, like any medical procedure, it carries a small risk of complications such as infection, bleeding, or damage to the vein or surrounding tissues.
Dicloxacillin is a type of antibiotic known as a penicillinase-resistant penicillin. It is used to treat infections caused by bacteria that are resistant to other types of penicillins. Dicloxacillin is effective against many gram-positive cocci, including staphylococci that produce penicillinases (enzymes that destroy penicillins).
The medical definition of dicloxacillin is:
"A semi-synthetic antibiotic derived from 6-aminopenicillanic acid and dichloroacetyl coenzyme A. It is resistant to staphylococcal penicillinases and is used to treat infections caused by susceptible organisms, including Staphylococcus aureus and Streptococcus pyogenes."
Dicloxacillin is available in oral capsule form and is typically taken two to four times daily, depending on the severity of the infection. It is important to take dicloxacillin for the entire prescribed course of treatment, even if symptoms improve, to ensure that the infection is completely treated and to reduce the risk of antibiotic resistance.
Like all antibiotics, dicloxacillin can cause side effects, including gastrointestinal symptoms such as nausea, vomiting, and diarrhea. It may also cause allergic reactions in some people, ranging from mild skin rashes to life-threatening anaphylaxis. People with a history of penicillin allergy should inform their healthcare provider before taking dicloxacillin or any other antibiics.
Ischemic colitis is a condition characterized by inflammation of the large intestine (colon) due to reduced blood flow to the area. This reduction in blood flow, also known as ischemia, can be caused by various factors such as narrowing or blockage of the blood vessels that supply the colon, low blood pressure, or certain medications.
Symptoms of ischemic colitis may include sudden abdominal pain, bloody diarrhea, nausea, vomiting, and fever. In severe cases, it can lead to tissue death, perforation of the colon, and sepsis. Treatment typically involves supportive care such as fluid replacement, bowel rest, and antibiotics. In some cases, surgery may be necessary to remove damaged tissue or restore blood flow to the area.
Nogalamycin is not typically considered as a medical term, but it is a type of antibiotic that is used in research and microbiology. Here's the definition from a scientific perspective:
Nogalamycin is an anthracycline antitumor antibiotic produced by Streptomyces nogalater. It is a DNA-intercalating agent, which means it can insert itself between the base pairs of DNA and disrupt the structure and function of the genetic material in bacteria and cancer cells. Nogalamycin has been studied for its potential use as an anticancer drug, but its clinical use has been limited due to toxicity concerns.
Fat emulsions for intravenous use are a type of parenteral nutrition solution that contain fat in the form of triglycerides, which are broken down and absorbed into the body to provide a source of energy and essential fatty acids. These emulsions are typically used in patients who are unable to consume food orally or enterally, such as those with gastrointestinal tract disorders, malabsorption syndromes, or severe injuries.
The fat emulsion is usually combined with other nutrients, such as carbohydrates and amino acids, to create a complete parenteral nutrition solution that meets the patient's nutritional needs. The emulsion is administered through a vein using a sterile technique to prevent infection.
Fat emulsions are typically made from soybean oil or a mixture of soybean and medium-chain triglyceride (MCT) oils. MCTs are more easily absorbed than long-chain triglycerides (LCTs), which are found in soybean oil, and may be used in patients with malabsorption syndromes or other conditions that affect fat absorption.
It is important to monitor patients receiving intravenous fat emulsions for signs of complications such as infection, hyperlipidemia (elevated levels of fats in the blood), and liver function abnormalities.
Soybean oil is a vegetable oil extracted from the seeds of the soybean (Glycine max). It is one of the most widely consumed cooking oils and is also used in a variety of food and non-food applications.
Medically, soybean oil is sometimes used as a vehicle for administering certain medications, particularly those that are intended to be absorbed through the skin. It is also used as a dietary supplement and has been studied for its potential health benefits, including its ability to lower cholesterol levels and reduce the risk of heart disease.
However, it's important to note that soybean oil is high in omega-6 fatty acids, which can contribute to inflammation when consumed in excess. Therefore, it should be used in moderation as part of a balanced diet.
An emulsion is a type of stable mixture of two immiscible liquids, such as oil and water, which are normally unable to mix together uniformly. In an emulsion, one liquid (the dispersed phase) is broken down into small droplets and distributed throughout the other liquid (the continuous phase), creating a stable, cloudy mixture.
In medical terms, emulsions can be used in various pharmaceutical and cosmetic applications. For example, certain medications may be formulated as oil-in-water or water-in-oil emulsions to improve their absorption, stability, or palatability. Similarly, some skincare products and makeup removers contain emulsifiers that help create stable mixtures of water and oils, allowing for effective cleansing and moisturizing.
Emulsions can also occur naturally in the body, such as in the digestion of fats. The bile salts produced by the liver help to form small droplets of dietary lipids (oil) within the watery environment of the small intestine, allowing for efficient absorption and metabolism of these nutrients.
Nonesterified fatty acids (NEFA), also known as free fatty acids (FFA), refer to fatty acid molecules that are not bound to glycerol in the form of triglycerides or other esters. In the bloodstream, NEFAs are transported while bound to albumin and can serve as a source of energy for peripheral tissues. Under normal physiological conditions, NEFA levels are tightly regulated by the body; however, elevated NEFA levels have been associated with various metabolic disorders such as insulin resistance, obesity, and type 2 diabetes.
Lipoprotein-X (Lp-X) is a type of lipoprotein that is typically found in the blood under certain pathological conditions. Unlike other lipoproteins such as low-density lipoprotein (LDL) or high-density lipoprotein (HDL), Lp-X does not contain apolipoproteins and is not associated with cholesterol transport. Instead, Lp-X is rich in free cholesterol and phospholipids, and it can be formed when there is an increase in the concentration of these lipids in the blood due to the breakdown of cell membranes or other lipoproteins.
Lp-X is often found in the blood of patients with liver diseases such as cirrhosis or hepatitis, as well as in those with severe malnutrition or who have experienced massive trauma. It can also be present in the blood of pregnant women, particularly those with preeclampsia or HELLP syndrome.
Because Lp-X lacks apolipoproteins, it is not recognized by the liver and cannot be cleared from the blood efficiently. As a result, high levels of Lp-X can contribute to the development of fatty liver disease, inflammation, and other complications associated with liver dysfunction.
Propofol is a short-acting medication that is primarily used for the induction and maintenance of general anesthesia during procedures such as surgery. It belongs to a class of drugs called hypnotics or sedatives, which work by depressing the central nervous system to produce a calming effect. Propofol can also be used for sedation in mechanically ventilated patients in intensive care units and for procedural sedation in various diagnostic and therapeutic procedures outside the operating room.
The medical definition of Propofol is:
A rapid-onset, short-duration intravenous anesthetic agent that produces a hypnotic effect and is used for induction and maintenance of general anesthesia, sedation in mechanically ventilated patients, and procedural sedation. It acts by enhancing the inhibitory effects of gamma-aminobutyric acid (GABA) in the brain, leading to a decrease in neuronal activity and a reduction in consciousness. Propofol has a rapid clearance and distribution, allowing for quick recovery after discontinuation of its administration.
"Health personnel" is a broad term that refers to individuals who are involved in maintaining, promoting, and restoring the health of populations or individuals. This can include a wide range of professionals such as:
1. Healthcare providers: These are medical doctors, nurses, midwives, dentists, pharmacists, allied health professionals (like physical therapists, occupational therapists, speech therapists, dietitians, etc.), and other healthcare workers who provide direct patient care.
2. Public health professionals: These are individuals who work in public health agencies, non-governmental organizations, or academia to promote health, prevent diseases, and protect populations from health hazards. They include epidemiologists, biostatisticians, health educators, environmental health specialists, and health services researchers.
3. Health managers and administrators: These are professionals who oversee the operations, finances, and strategic planning of healthcare organizations, such as hospitals, clinics, or public health departments. They may include hospital CEOs, medical directors, practice managers, and healthcare consultants.
4. Health support staff: This group includes various personnel who provide essential services to healthcare organizations, such as medical records technicians, billing specialists, receptionists, and maintenance workers.
5. Health researchers and academics: These are professionals involved in conducting research, teaching, and disseminating knowledge related to health sciences, medicine, public health, or healthcare management in universities, research institutions, or think tanks.
The World Health Organization (WHO) defines "health worker" as "a person who contributes to the promotion, protection, or improvement of health through prevention, treatment, rehabilitation, palliation, health promotion, and health education." This definition encompasses a wide range of professionals working in various capacities to improve health outcomes.