Picrasma
Directories as Topic
Biological Products
Malaysia
Plants, Medicinal
Anti-Obesity Agents
Books
Anti-inflammatory alkaloids from the stems of Picrasma quassioides BENNET. (1/1)
During further chemical and biological investigations of Picrasma quassioides BENNET, four new bis-beta-carboline alkaloids, quassidines E-H (1-4), and three new beta-carboline alkaloids, canthin-16-one-14-butyric acid (5), 3-(1,1-dimethoxylmethyl)-beta-carboline (6), and 6,12-dimethoxy-3-formyl-beta-carboline (7), were isolated from its anti-inflammatory CHCl(3)-soluble fraction. Structures of new compounds were elucidated and characterized by MS and NMR analysis. A plausible biogenetic pathway for quassidine E (1), the first bis-beta-carboline alkaloid in which a canthin-6-one moiety and a beta-carboline moiety were connected together by a single carbon-carbon bond from the nature, was proposed. Quassidines E-G (1-3) showed potent inhibitory activity on the production of nitric oxide (NO), tumor necrosis factor alpha (TNF-alpha), or interleukin 6 (IL-6) in mouse monocyte-macrophage RAW264.7 cells stimulated by lipopolysaccharide (LPS). Analysis of anti-inflammatory activity of all beta-carboline and bis-beta-carboline alkaloids from P. quassioides showed that the carbonyl groups or double carbon-carbon bonds at C-14 for beta-carbolines and C-14' for bis-beta-carbolines were bioactive groups for their in vitro anti-inflammatory activity. Structure-activity relationship of these compounds on inhibitory activity of the three inflammatory cytokines was discussed. (+info)"Picrasma" is a botanical term that refers to a genus of shrubs and trees, also known as Quassia, which are native to the Americas. The bark and roots of these plants have been used in traditional medicine for their bitter taste and insecticidal properties.
However, if you are looking for a medical definition related to the use of "Picrasma" in a clinical context, it is important to note that there is no commonly recognized medical term or definition specifically associated with "Picrasma". If a healthcare provider or researcher is discussing "Picrasma", they are likely referring to one or more of the specific plant species within this genus and their potential medicinal uses.
Some proponents of herbal medicine believe that extracts from "Picrasma" plants may have anti-inflammatory, antimicrobial, and antipyretic properties, among others. However, it is important to note that these claims are not universally accepted by the medical community, and more research is needed to establish the safety and efficacy of "Picrasma" as a treatment for any specific medical condition.
If you have any questions about the use of "Picrasma" or any other herbal remedies, it is always best to consult with a qualified healthcare provider who can provide evidence-based advice and guidance.
A medical directory is a collection of information about healthcare professionals, organizations, and facilities, arranged in a systematic and searchable manner. Medical directories can be found in both print and digital formats and serve as a valuable resource for patients, doctors, researchers, and other healthcare providers.
The information contained in medical directories may include the names and contact details of physicians, specialists, and other healthcare professionals, along with their qualifications, areas of expertise, and professional affiliations. Medical directories may also provide information about hospitals, clinics, research institutions, and other healthcare organizations, including their services, accreditation status, and quality indicators.
Medical directories can be used for a variety of purposes, such as finding a specialist in a particular field, locating a nearby hospital or clinic, verifying the credentials of a healthcare provider, or conducting research on healthcare trends and outcomes. Some medical directories may also include patient reviews and ratings, which can help consumers make informed decisions about their care.
Examples of medical directories include the American Medical Association (AMA) Physician Masterfile, the National Provider Identifier (NPI) Registry, and the Healthcare Bluebook.
According to the United States Food and Drug Administration (FDA), biological products are "products that are made from or contain a living organism or its derivatives, such as vaccines, blood and blood components, cells, genes, tissues, and proteins." These products can be composed of sugars, proteins, nucleic acids, or complex combinations of these substances, and they can come from many sources, including humans, animals, microorganisms, or plants.
Biological products are often used to diagnose, prevent, or treat a wide range of medical conditions, and they can be administered in various ways, such as through injection, inhalation, or topical application. Because biological products are derived from living organisms, their manufacturing processes can be complex and must be tightly controlled to ensure the safety, purity, and potency of the final product.
It's important to note that biological products are not the same as drugs, which are chemically synthesized compounds. While drugs are designed to interact with specific targets in the body, such as enzymes or receptors, biological products can have more complex and varied mechanisms of action, making them potentially more difficult to characterize and regulate.
I'm sorry for any confusion, but "Malaysia" is not a medical term or concept. It is a country located in Southeast Asia, consisting of thirteen states and three federal territories. If you have any questions about Malaysia's geography, culture, or people, I would be happy to try to help answer those! However, if you have a question related to medicine or healthcare, please provide more details so I can give you an accurate and helpful response.
Medicinal plants are defined as those plants that contain naturally occurring chemical compounds which can be used for therapeutic purposes, either directly or indirectly. These plants have been used for centuries in various traditional systems of medicine, such as Ayurveda, Chinese medicine, and Native American medicine, to prevent or treat various health conditions.
Medicinal plants contain a wide variety of bioactive compounds, including alkaloids, flavonoids, tannins, terpenes, and saponins, among others. These compounds have been found to possess various pharmacological properties, such as anti-inflammatory, analgesic, antimicrobial, antioxidant, and anticancer activities.
Medicinal plants can be used in various forms, including whole plant material, extracts, essential oils, and isolated compounds. They can be administered through different routes, such as oral, topical, or respiratory, depending on the desired therapeutic effect.
It is important to note that while medicinal plants have been used safely and effectively for centuries, they should be used with caution and under the guidance of a healthcare professional. Some medicinal plants can interact with prescription medications or have adverse effects if used inappropriately.
Anti-obesity agents are medications that are used to treat obesity and overweight. They work by reducing appetite, increasing feelings of fullness, decreasing fat absorption, or increasing metabolism. Some examples of anti-obesity agents include orlistat, lorcaserin, phentermine, and topiramate. These medications are typically used in conjunction with diet and exercise to help people lose weight and maintain a healthy body weight. It's important to note that these medications can have side effects and should be used under the close supervision of a healthcare provider.
I apologize for any confusion, but "books" is a general term that refers to bound sets of pages that are printed or written with text, illustrations, or signs, and are meant to be read, studied, or consulted. It does not have a specific medical definition. If you're looking for information about a specific medical term or concept, please let me know and I'd be happy to help!
In the context of medical terminology, a directory generally refers to a list or catalog of healthcare providers, organizations, or services. It can be used to provide information about various aspects such as their names, contact details, specialties, qualifications, and locations. This type of directory is often found in hospitals, clinics, insurance companies, and medical associations to facilitate access to healthcare resources for patients, practitioners, and administrative purposes.