Plasma cell granuloma pulmonary. Medical search. Definitions

A slow-growing benign pseudotumor in which plasma cells greatly outnumber the inflammatory cells.

A tumor-like inflammatory lesion of the lung that is composed of PLASMA CELLS and fibrous tissue. It is also known as an inflammatory pseudotumor, often with calcification and measuring between 2 and 5 cm in diameter.

A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.

'Gingival diseases' is a general term for conditions affecting the soft tissues surrounding and supporting the teeth, primarily characterized by inflammation, bleeding, redness, or swelling, which can progress to periodontal disease if left untreated.

A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.

Specialized forms of antibody-producing B-LYMPHOCYTES. They synthesize and secrete immunoglobulin. They are found only in lymphoid organs and at sites of immune responses and normally do not circulate in the blood or lymph. (Rosen et al., Dictionary of Immunology, 1989, p169 & Abbas et al., Cellular and Molecular Immunology, 2d ed, p20)

Characteristic cells of granulomatous hypersensitivity. They appear as large, flattened cells with increased endoplasmic reticulum. They are believed to be activated macrophages that have differentiated as a result of prolonged antigenic stimulation. Further differentiation or fusion of epithelioid cells is thought to produce multinucleated giant cells (GIANT CELLS).

'Mandibular diseases' refer to various medical conditions that primarily affect the structure, function, or health of the mandible (lower jawbone), including but not limited to infections, tumors, developmental disorders, and degenerative diseases.

Maxillary diseases refer to various medical conditions primarily affecting the maxilla (upper jaw) bone, including inflammatory processes, tumors, cysts, or traumatic injuries, which may cause symptoms such as pain, swelling, or functional impairment.

FIBROUS DYSPLASIA OF BONE involving only one bone.

An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.

A rare, aggressive variant of MULTIPLE MYELOMA characterized by the circulation of excessive PLASMA CELLS in the peripheral blood. It can be a primary manifestation of multiple myeloma or develop as a terminal complication during the disease.

Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.

A disorder of the skin, the oral mucosa, and the gingiva, that usually presents as a solitary polypoid capillary hemangioma often resulting from trauma. It is manifested as an inflammatory response with similar characteristics to those of a granuloma.

Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)

Interleukin-13 fusion cytotoxin arrests Schistosoma mansoni egg-induced pulmonary granuloma formation in mice. (1/31)

Schistosoma mansoni egg-induced lung pathology requires the actions of interleukin (IL)-4 and IL-13. Because receptors for IL-4 and IL-13 share chains, we examined the effect of a fusion protein comprised of IL-13 and Pseudomonas exotoxin (IL13-PE) on the development of pulmonary granulomas in mice. At day 8 after an intravenous injection of live S. mansoni eggs, whole lung samples from IL13-PE-treated mice exhibited significantly lower IL-4 and IL-13 gene expression, smaller granulomas, decreased collagen levels, and increased IL-13 receptor alpha2 gene expression compared to controls. The therapeutic effects of IL13-PE were also observed at day 16 despite the termination of IL13-PE treatment at day 8. These studies demonstrate that targeting IL-4- and IL-13- responsive cells with IL13-PE effectively arrests S. mansoni egg granuloma formation. (+info)

A case report of inflammatory pseudotumor of the lung: rapid recurrence appearing as multiple lung nodules. (2/31)

An inflammatory pseudotumor (IPT), known as a plasma cell granuloma, is a relatively uncommon neoplasm with an unidentified etiology. To our knowledge, an early relapse with multiple lung nodules following lung resection and occurrences in multiple organs is extremely rare. The patient was a 49-year-old man who presented with left chest pain and fever. A chest film demonstrated an 8x8 cm mass in the left lower lobe. During thoracotomy in April 2001, a mass was seen to have invaded the diaphragm with remarkable pleural adhesion. The intraoperative pathological diagnosis was infiltration of inflammatory cells with no malignancy. Therefore, a partial resection of the left lower lobe was performed. Three months after the thoracotomy, a chest CT scan disclosed multiple nodular opacities bilaterally, and an open lung-biopsy of the right lung was performed in January 2002. His past history included an excision of a mass on the penis in another hospital in 1994 and a subcutaneous mass that appeared on the right thigh and disappeared spontaneously following a needle biopsy in 1999. Pathologically there was no fundamental difference among his present lesion and the former two. The pathological diagnosis at each occurrence was inflammatory pseudotumor (IPT). In immunohistochemical study, the staining with smooth muscle actin cells was positive, but was negative for the staining with anaplastic lymphoma kinase (ALK). With no evidence of a neoplastic process, these histopathological and immunohistochemical findings could imply that this case may be a postinflammatory reparative reaction, although his condition exhibited the clinically aggressive behavior of suspected lung metastasis. (+info)

Pulmonary inflammatory pseudotumor--a report of 28 cases. (3/31)

BACKGROUND: Pulmonary inflammatory pseudotumor is an uncommon benign lesion of the lung. In Korea, most literature of the pulmonary inflammatory pseudotumor was case reports. METHODS: We collected 28 cases of pulmonary inflammatory pseudotumor in Korea. This collective series included 4 cases from our hospital and 24 cases were reviewed from the literature since 1977. The analysis involved the age, sex, chief complaint, hematologic examination, size and location of the lesion, cavity formation, presence of calcification and treatment method. RESULTS: Male was more prevalent (81.5%) than female and mean age was 37.9 years old (6-63 yrs). Chief complaints were cough (44.4%), chest pain (29.6%), fever (22.2%), hemoptysis (15%), sputum (15%) and dyspnea (11.1%). There were asymptomatic cases in 11.1%. Hematologic examination revealed normal finding (53.3%) and anemia (20%). The mean size of the lesion was 4.76 cm (1.5-14 cm) and the locations were parenchymal (85.7%), endobronchial (10.7%) and endotracheal (3.6%). Except the endotracheal case, the lesions were in the right (46.4%), the left (42.8%) and bilateral (7.1%). Calcifications (18.5%) and cavitations (11.1%) were present. Diagnostic methods were open thoracotomy (82.1%), bronchoscopy (3.6%), needle aspiration biopsy (7.1%) and core needle gun biopsy (7.1%). Treatments were surgery (85.2%), steroid therapy (7.4%), rigid bronchoscopic removal (3.7%) and observation (3.7%). Postoperative recurrence occurred in only 1 case (4.3%). CONCLUSION: Pulmonary inflammatory pseudotumor was more prevalent in the male, and patients presented with the respiratory symptoms were common. It was necessary to do surgery in most cases for diagnosis and/or treatment. (+info)

Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts. (4/31)

Interleukin-13 (IL-13) has emerged as a major cytokine mediator of fibroblast activation and pulmonary fibrosis. Normal (from noninflamed lung), Th1-type (induced by the pulmonary embolization of purified peptide derivative-coated beads in mice sensitized to purified peptide derivative), and Th2-type (induced by the pulmonary embolization of Schistosoma mansoni egg antigen-coated beads in mice sensitized with S. mansoni eggs) primary fibroblast cell lines all exhibited constitutive gene expression of two receptor chains that bind and signal IL-13-mediated cellular events: IL-4Ralpha and IL-13Ralpha1. However, all three fibroblast cell lines exhibited divergent synthetic and proliferative responses to the exogenous addition of either recombinant IL-13 or a chimeric protein comprised of IL-13 and a truncated version of Pseudomonas exotoxin (IL13-PE), which targets and kills IL-13 receptor overexpressing cells. The exogenous addition of IL-13 to Th1-type and Th2-type fibroblast cultures significantly increased the cellular expression of IL-13Ralpha2, which may function as an IL-13 decoy receptor. After a 24-hour exposure to IL-13, the total collagen generation and cellular proliferation by Th2-type fibroblasts were significantly higher than that observed in similar numbers of normal and Th1-type fibroblasts. In addition IL13-PE, which binds with highest affinity to IL-13Ralpha2, exhibited down-regulatory effects on proliferation and matrix generation expression by Th1- and Th2-type, but not normal, fibroblasts. Thus, these data demonstrate that fibroblasts derived from murine pulmonary granulomas exhibit divergent expression of functional IL-13 receptor and this expression dictates the responsiveness and susceptibility to recombinant IL-13 and IL-13 immunotoxin, respectively. (+info)

Seven patients with plasma cell granuloma (inflammatory pseudotumor) of the lung, including two with intrabronchial growth: an immunohistochemical and electron microscopic study. (5/31)

Seven patients (mean age, 50.7 +/- 20.4 years; range 21-77) with plasma cell granuloma (PCG) of the lung are reported. Cough and sputum were the most common presenting symptoms, followed by fever. Elevated erythrocyte sedimentation rate and serum C-reactive protein levels were found in all patients tested. Radiologically, five cases presented as solitary, well-circumscribed masses and two as ill-defined, pneumonia-like densities. One showed focal calcification. No predilection of occurrence was observed in either lobe of the lung. Histologically, the lesions consisted of a proliferation of mature plasma cells and reticulo-endothelial cells supported by a stroma of granulation tissue, with varying degrees of myxoid change or collagenization. Angioinvasion within the lesion was observed in 4 of the 7 cases. Immunohistochemical staining revealed the IgG-predominant polyclonal nature of the plasma cells, indicating a reactive inflammatory process rather than a neoplastic one. Electron microscopy confirmed the benign nature of the plasma cells with fibroblast and myofibroblast proliferation admixed with that of other inflammatory cells. (+info)

Endobronchial pseudo-tumour caused by herpes simplex. (6/31)

Herpes simplex virus (HSV) causes tracheobronchitis and pneumonitis; however, to date, there has only been one report of an endobronchial mass caused by HSV type II. This case study describes a 68-yr-old female with severe kyphoscoliosis who was intubated for acute on chronic hypercapnic respiratory failure and developed blood-tinged endotracheal secretions. Fibreoptic bronchoscopy demonstrated an endobronchial mass in the right middle lobe. Cultures grew HSV type I and biopsy specimens demonstrated cytopathological changes consistent with HSV infection. This is the first reported case of HSV type I presenting as an endobronchial tumour. (+info)

A case of pulmonary inflammatory pseudotumor: Recurrence appearing as several consolidative lesions after complete resection. (7/31)

Inflammatory pseudotumor (plasma cell granuloma) of the lung is an uncommon nonneoplastic tumor of unknown origin. This tumor typically manifests as a solitary, peripheral, and sharply circumscribed mass. Multiple lesions are seen in about 5% of cases. Resection is recommended for both diagnosis and treatment, and this tumor does not generally recur after complete resection. Here, we report a case of recurrent inflammatory pseudotumor after complete resection; the recurrence was detected as a series of bilateral consolidated lesions with an internal air bronchogram. This is an unusual finding with regard to inflammatory pseudotumors. (+info)

Endobronchial inflammatory pseudotumor: a case report. (8/31)

Inflammatory pseudotumor of the lung is a rare form of benign neoplasia and is generally characterized by a solitary pulmonary nodule. The endobronchial presentation is uncommon. Conservative surgery remains the treatment of choice, and surgeons should always strive to achieve tumor-free margins due to the possibility of local recidivism. This article reports the case of a 36-year-old male patient with recurrent attacks of wheezing and cough. The patient underwent successful bronchoplasty for the resection of an endobronchial inflammatory pseudotumor. (+info)

A "Plasma Cell Granuloma" is a specific type of granulomatous inflammation that is characterized by the presence of numerous plasma cells. Plasma cells are white blood cells that produce antibodies, which are proteins that help the body fight off infections and diseases. In a Plasma Cell Granuloma, there is an excessive accumulation of these cells, leading to the formation of a nodular lesion or mass.

Plasma Cell Granulomas can occur in various organs, including the skin, lungs, gastrointestinal tract, and oral cavity. They are often associated with chronic inflammation, autoimmune disorders, or malignancies. The exact cause of Plasma Cell Granulomas is not always known, but they may be triggered by infections, foreign bodies, or other stimuli that induce an immune response.

Histologically, a Plasma Cell Granuloma is composed of a central area of plasma cells surrounded by a rim of lymphocytes and macrophages. The lesion may also contain multinucleated giant cells, eosinophils, and other inflammatory cells. Treatment options for Plasma Cell Granulomas depend on the location and extent of the lesion, as well as the underlying cause. Surgical excision is often curative, but medical therapy may be necessary in some cases.

Pulmonary plasma cell granuloma is a benign lung lesion characterized by the accumulation of plasma cells and the formation of granulomas. It is also known as inflammatory pseudotumor or plasma cell histiocytoma. The etiology of pulmonary plasma cell granuloma remains unclear, but it is thought to be related to a chronic inflammatory response or an abnormal immune reaction.

The lesion typically consists of a mass or nodule in the lung tissue, which may be discovered incidentally on chest imaging. Symptoms, if present, may include cough, chest pain, and shortness of breath. The diagnosis is usually made by histopathological examination of a biopsy specimen, which shows a mixture of plasma cells, lymphocytes, and histiocytes, with the formation of granulomas.

Treatment is generally not necessary unless the lesion is causing symptoms or growing in size. In such cases, surgical resection may be recommended. The prognosis is excellent, with a low risk of recurrence after surgical removal.

A giant cell granuloma is a type of non-cancerous (benign) lesion characterized by the presence of large collections of immune cells called macrophages, which have fused together to form multinucleated giant cells. These lesions can occur in various tissues throughout the body but are most commonly found in the oral cavity and jawbone.

Giant cell granulomas can be further classified into two types: central (or bone) giant cell granuloma and peripheral giant cell granuloma. Central giant cell granulomas arise from the bone, while peripheral giant cell granulomas occur in the soft tissues of the gingiva or mouth lining.

Central giant cell granulomas are more aggressive than peripheral ones and can cause significant bone destruction if left untreated. They typically affect younger individuals, with a higher prevalence in females than males. The exact cause of central giant cell granulomas is not well understood but may be associated with local trauma, hormonal imbalances, or genetic factors.

Peripheral giant cell granulomas are less aggressive and usually present as painless, slow-growing nodules on the gums. They typically affect adults, with a higher prevalence in females than males. Peripheral giant cell granulomas may be associated with local irritants such as plaque, calculus, or dental restorations.

Treatment for giant cell granulomas depends on their size, location, and aggressiveness. Surgical excision is the most common treatment approach, but other options such as curettage, corticosteroid injections, or medication therapy may also be considered. Regular follow-up appointments with a healthcare provider are essential to monitor for recurrence.

Gingival diseases are infections or inflammations that affect the gingiva, which is the part of the gum around the base of the teeth. These diseases can be caused by bacteria found in dental plaque and can lead to symptoms such as redness, swelling, bleeding, and receding gums. If left untreated, gingival diseases can progress to periodontal disease, a more serious condition that can result in tooth loss. Common types of gingival diseases include gingivitis and periodontitis.

A granuloma is a small, nodular inflammatory lesion that occurs in various tissues in response to chronic infection, foreign body reaction, or autoimmune conditions. Histologically, it is characterized by the presence of epithelioid macrophages, which are specialized immune cells with enlarged nuclei and abundant cytoplasm, often arranged in a palisading pattern around a central area containing necrotic debris, microorganisms, or foreign material.

Granulomas can be found in various medical conditions such as tuberculosis, sarcoidosis, fungal infections, and certain autoimmune disorders like Crohn's disease. The formation of granulomas is a complex process involving both innate and adaptive immune responses, which aim to contain and eliminate the offending agent while minimizing tissue damage.

Plasma cells are a type of white blood cell that are derived from B cells (another type of white blood cell) and are responsible for producing antibodies. Antibodies are proteins that help the body to fight against infections by recognizing and binding to specific antigens, such as bacteria or viruses. Plasma cells are found in the bone marrow, spleen, and lymph nodes, and they play a crucial role in the immune system's response to infection.

Plasma cells are characterized by their large size, eccentric nucleus, and abundant cytoplasm filled with rough endoplasmic reticulum, which is where antibody proteins are synthesized and stored. When activated, plasma cells can produce and secrete large amounts of antibodies into the bloodstream and lymphatic system, where they can help to neutralize or eliminate pathogens.

It's worth noting that while plasma cells play an important role in the immune response, abnormal accumulations of these cells can also be a sign of certain diseases, such as multiple myeloma, a type of cancer that affects plasma cells.

Epithelioid cells are a type of cell that can be found in certain types of tissue in the body, including connective tissue and some organs. These cells have a characteristic appearance under a microscope, with an enlarged, oval or round shape and a pale, abundant cytoplasm. They may also have a nucleus that is centrally located and has a uniform, rounded shape.

Epithelioid cells are often seen in the context of inflammation or disease, particularly in relation to granulomatous disorders such as sarcoidosis and tuberculosis. In these conditions, epithelioid cells can form clusters known as granulomas, which are a hallmark of the diseases. The exact function of epithelioid cells is not fully understood, but they are thought to play a role in the immune response and may help to contain and eliminate foreign substances or pathogens from the body.

Mandibular diseases refer to conditions that affect the mandible, or lower jawbone. These diseases can be classified as congenital (present at birth) or acquired (developing after birth). They can also be categorized based on the tissues involved, such as bone, muscle, or cartilage. Some examples of mandibular diseases include:

1. Mandibular fractures: These are breaks in the lower jawbone that can result from trauma or injury.
2. Osteomyelitis: This is an infection of the bone and surrounding tissues, which can affect the mandible.
3. Temporomandibular joint (TMJ) disorders: These are conditions that affect the joint that connects the jawbone to the skull, causing pain and limited movement.
4. Mandibular tumors: These are abnormal growths that can be benign or malignant, and can develop in any of the tissues of the mandible.
5. Osteonecrosis: This is a condition where the bone tissue dies due to lack of blood supply, which can affect the mandible.
6. Cleft lip and palate: This is a congenital deformity that affects the development of the face and mouth, including the lower jawbone.
7. Mandibular hypoplasia: This is a condition where the lower jawbone does not develop properly, leading to a small or recessed chin.
8. Developmental disorders: These are conditions that affect the growth and development of the mandible, such as condylar hyperplasia or hemifacial microsomia.

Maxillary diseases refer to conditions that affect the maxilla, which is the upper bone of the jaw. This bone plays an essential role in functions such as biting, chewing, and speaking, and also forms the upper part of the oral cavity, houses the upper teeth, and supports the nose and the eyes.

Maxillary diseases can be caused by various factors, including infections, trauma, tumors, congenital abnormalities, or systemic conditions. Some common maxillary diseases include:

1. Maxillary sinusitis: Inflammation of the maxillary sinuses, which are air-filled cavities located within the maxilla, can cause symptoms such as nasal congestion, facial pain, and headaches.
2. Periodontal disease: Infection and inflammation of the tissues surrounding the teeth, including the gums and the alveolar bone (which is part of the maxilla), can lead to tooth loss and other complications.
3. Maxillary fractures: Trauma to the face can result in fractures of the maxilla, which can cause pain, swelling, and difficulty breathing or speaking.
4. Maxillary cysts and tumors: Abnormal growths in the maxilla can be benign or malignant and may require surgical intervention.
5. Oral cancer: Cancerous lesions in the oral cavity, including the maxilla, can cause pain, swelling, and difficulty swallowing or speaking.

Treatment for maxillary diseases depends on the specific condition and its severity. Treatment options may include antibiotics, surgery, radiation therapy, or chemotherapy. Regular dental check-ups and good oral hygiene practices can help prevent many maxillary diseases.

Fibrous dysplasia, monostotic is a benign bone disorder that affects a single bone (monostotic) and is characterized by the replacement of normal bone tissue with fibrous (scar-like) tissue. This results in the formation of abnormal bone that is weakened and more susceptible to fractures. The lesions can cause deformities, pain, and decreased mobility, depending on their size and location. Monostotic fibrous dysplasia is the most common form of fibrous dysplasia, accounting for approximately 70-80% of all cases. It typically manifests during childhood or adolescence and may stabilize or progress slowly over time. In some cases, it can be associated with endocrine disorders such as precocious puberty, hyperthyroidism, or growth hormone excess.

Sarcoidosis is a multi-system disorder characterized by the formation of granulomas (small clumps of inflammatory cells) in various organs, most commonly the lungs and lymphatic system. These granulomas can impair the function of the affected organ(s), leading to a variety of symptoms. The exact cause of sarcoidosis is unknown, but it's thought to be an overactive immune response to an unknown antigen, possibly triggered by an infection, chemical exposure, or another environmental factor.

The diagnosis of sarcoidosis typically involves a combination of clinical evaluation, imaging studies (such as chest X-rays and CT scans), and laboratory tests (including blood tests and biopsies). While there is no cure for sarcoidosis, treatment may be necessary to manage symptoms and prevent complications. Corticosteroids are often used to suppress the immune system and reduce inflammation, while other medications may be prescribed to treat specific organ involvement or symptoms. In some cases, sarcoidosis may resolve on its own without any treatment.

Plasma cell leukemia (PCL) is a rare and aggressive type of cancer that involves the uncontrolled multiplication of malignant plasma cells in the bone marrow, blood, and sometimes in other organs. Plasma cells are a type of white blood cell that produces antibodies to help fight infections. In PCL, the malignant plasma cells produce abnormal antibodies called M-proteins or paraproteins, which can accumulate in various tissues and cause damage.

PCL is typically classified into two types: primary and secondary. Primary PCL is a distinct clinical entity that presents with more than 20% plasma cells in the bone marrow and/or blood. Secondary PCL is a complication of multiple myeloma, a more common type of plasma cell cancer, and occurs when the malignant plasma cells spread from the bone marrow to the blood.

The symptoms of PCL are similar to those of other types of leukemia and may include fatigue, weakness, weight loss, frequent infections, easy bruising or bleeding, and bone pain. Diagnosis of PCL typically involves a combination of clinical evaluation, laboratory tests, imaging studies, and bone marrow aspiration and biopsy. Treatment options for PCL may include chemotherapy, stem cell transplantation, radiation therapy, and targeted therapies. The prognosis for patients with PCL is generally poor, with a median survival time of less than one year.

A granuloma is a type of organized immune response that occurs when the body encounters a foreign substance that it cannot eliminate. A "foreign-body" granuloma specifically refers to this reaction in response to an exogenous material, such as a splinter, suture, or other types of medical implants.

Foreign-body granulomas are characterized by the formation of a collection of immune cells, including macrophages and lymphocytes, which surround and attempt to isolate the foreign material. Over time, this collection of immune cells can become walled off and form a well-circumscribed mass or nodule.

Foreign-body granulomas may cause localized symptoms such as pain, swelling, or inflammation, depending on their location and size. In some cases, they may also lead to complications such as infection or tissue damage. Treatment typically involves removing the foreign body, if possible, followed by anti-inflammatory therapy to manage any residual symptoms or complications.

A pyogenic granuloma is not precisely a "granuloma" in the strict medical definition, which refers to a specific type of tissue reaction characterized by chronic inflammation and the formation of granulation tissue. Instead, a pyogenic granuloma is a benign vascular tumor that occurs most frequently on the skin or mucous membranes.

Pyogenic granulomas are typically characterized by their rapid growth, bright red to dark red color, and friable texture. They can bleed easily, especially when traumatized. Histologically, they consist of a mass of small blood vessels, surrounded by loose connective tissue and inflammatory cells.

The term "pyogenic" is somewhat misleading because these lesions are not actually associated with pus or infection, although they can become secondarily infected. The name may have originated from the initial mistaken belief that these lesions were caused by a bacterial infection.

Pyogenic granulomas can occur at any age but are most common in children and young adults. They can be caused by minor trauma, hormonal changes, or underlying medical conditions such as pregnancy or vasculitis. Treatment typically involves surgical excision, although other options such as laser surgery or cauterization may also be used.

Sarcoidosis, pulmonary is a specific form of sarcoidosis, which is a multisystem inflammatory disorder characterized by the formation of noncaseating granulomas (small clusters of immune cells) in one or more organs. In pulmonary sarcoidosis, these granulomas primarily affect the lungs, but can also involve the lymph nodes within the chest. The condition is often asymptomatic, but some individuals may experience symptoms such as cough, shortness of breath, chest pain, and fatigue. Pulmonary sarcoidosis can lead to complications like pulmonary fibrosis (scarring of lung tissue) and chronic interstitial lung disease, which can impact lung function and quality of life. The exact cause of sarcoidosis is unknown, but it is believed to involve an abnormal immune response triggered by exposure to certain antigens, such as environmental particles or infectious agents.

Pathology, Atlas of Pulmonary (2011-04-04), Inflammatory pseudotumor - Plasma cell granuloma Case 176, retrieved 2022-12-07 " ... pyogenic granuloma, and peripheral giant cell granuloma. Histopathological analysis of plasma cell granulomas have been found ... Typically, plasma cell granulomas appear microscopically as a lesional mass consisting of an abundance of plasma cells ... a plasma cell granuloma will display a dense population of morphologically similar plasma cells sporadically mixed together ...

https://en.wikipedia.org/wiki/Plasma_cell_granuloma

... plasma cells and heterophils. Mild numbers of mixed inflammatory cells were seen within the intestinal lamina propria. The ... small caseating granulomas within the lungs. The granulomas contained numerous large macrophages and multinucleated cells. Acid ... The third alligator had primarily pulmonary changes. The airways contained moderate numbers of heterophils, occasional mucous ... cells were used instead of the Vero cells. Inoculated cells were incubated in a 5% CO2 atmosphere at 37°C. Cells were examined ...

https://wwwnc.cdc.gov/eid/article/9/7/03-0085_article

This case illustrates how it is possible to utilize a technique used for cardiac surgery for tumors of pulmonary origin ... Plasma cell granuloma (PCG) is a rare benign tumor that is difficult to differentiate from malignancy. Depending on the ... Resection of a plasma cell granuloma combining a conventional posterolateral left-sided thoracotomy with a minimally invasive ... Plasma Cell Granuloma; Posterolateral thoracotomy; Minimally invasive valve surgery; Lobectomy National Category Cardiac and ...

http://liu.diva-portal.org/smash/record.jsf?pid=diva2:1367508

A solitary pulmonary nodule is defined as a discrete, well-marginated, rounded opacity less than or equal to 3 cm in diameter ... plasma cell granuloma, fibrous histiocytoma, xanthoma, pulmonary hyalinizing granuloma, pulmonary endometrioma, and ... Granular cell myoblastomas are of neural cell origin. A granular cell myoblastoma contains polygonal or spindle cells with ... Pulmonary tumorlets are minute collections of neuroendocrine cells scattered throughout the lung. Pulmonary tumorlets ...

https://emedicine.medscape.com/article/2139920-overview

Granuloma, Plasma Cell, Pulmonary. Plasma Cell Granuloma, Pulmonary. C11 - Eye Diseases. Granuloma, Plasma Cell, Orbital. ... G04 - Cell Physiological Phenomena. Cell Physiology. Cell Physiological Phenomena. G05 - Genetic Phenomena. Trans-Activation ( ... A11 - Cells. Erythroid Progenitor Cells. Erythroid Precursor Cells. Neoplasm Circulating Cells. Neoplastic Cells, Circulating. ...

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pulmonary plasma cell granuloma DOID:3677 * cervix uteri carcinoma in situ DOID:8991 ...

https://bio2vec.cbrc.kaust.edu.sa/bio2vec/details/1?iri=DOID:1513

pulmonary plasma cell granuloma DOID:3677 * no_name DOID:13630 * extrinsic allergic alveolitis ...

https://bio2vec.cbrc.kaust.edu.sa/bio2vec/details/1?iri=DOID:1532

Article: Intravascular plasma cell granuloma of the pulmonary artery. Zakkar M, Kanagasbay R.. Eur J Cardiothorac Surg 2013; 43 ...

https://aortainstitute.co.uk/who-we-are/meet-the-doctors/robin-kanagasabay/

10.1).* A dispersed population of lymphocytes and plasma cells is present throughout the biopsy. Granulomas are not a feature ... A similar pathologic process occurs in the lung as pulmonary hyalinizing granulomas. ... The active, infectious granulomas show the presence of caseous necrosis. The granulomas are hyalinized with or without ... or renal cell carcinoma), accounts for over 50% of the diagnoses. NHL (lymphoblastic lymphoma and mediastinal large B-cell ...

https://basicmedicalkey.com/mediastinum-2/

... plasma cells, fibroblasts, and collagen. Granulomas occur most commonly in the lungs and lymph nodes but can involve any organ ... Pulmonary function test Overview of Tests of Pulmonary Function Pulmonary function tests provide measures of airflow, lung ... Granulomas are collections of mononuclear cells and macrophages that differentiate into epithelioid and multinucleated giant ... Chest CT Scan in Pulmonary Sarcoidosis. This high-resolution CT of the chest of a patient with pulmonary sarcoidosis shows ...

https://www.msdmanuals.com/professional/pulmonary-disorders/sarcoidosis/sarcoidosis

Plasma cell granuloma. *Vascular neoplasm. ASJC Scopus subject areas. *Pulmonary and Respiratory Medicine ... IMTs consist of variable amounts of spindle cells, collagen, and inflammatory cells, including plasma cells, foamy histiocytes ... IMTs consist of variable amounts of spindle cells, collagen, and inflammatory cells, including plasma cells, foamy histiocytes ... IMTs consist of variable amounts of spindle cells, collagen, and inflammatory cells, including plasma cells, foamy histiocytes ...

https://mayoclinic.elsevierpure.com/en/publications/the-thoracic-mass-an-unusual-etiology

Plasma Cell Granuloma, Pulmonary. *Pneumonia. *Pulmonary Alveolar Proteinosis. *Pulmonary Atelectasis. *Pulmonary Edema ... IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. J Immunol. 2015 Dec 01; 195(11):5251-60. ... "Pulmonary Fibrosis" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Pulmonary Fibrosis" by people in this website by year, and ...

https://profiles.umassmed.edu/display/106137

Bronchial biopsies included plasma cells, neutrophil infiltrates, only isolated eosinophils, and no granulomas, providing the ... However, the treatment course was complicated by pulmonary cryptococcosis. The patient later developed non-infectious ... Granuloma/diagnóstico , Granuloma/etiologia , Exoftalmia/diagnóstico , Exoftalmia/etiologia ... Results: Granulomas were present in 47.7% of our sample, c-ANCA in 59.2%, and p-ANCA in 10.8%. Scleritis was significantly ...

https://pesquisa.bvsalud.org/controlecancer/?lang=pt&q=mh:Granulomatose+com+Poliangiite/complica%C3%A7%C3%B5es

... plasma cell granuloma (1), bronchiectasis (1), reactive lymphadenopathy (1). Tissue for analysis was collected prospectively ... pulmonary (9), splenic (1), ocular (1), cervical node (1), hypercalcaemia (1). The chest radiographic appearances were as ... There is oligoclonal expansion of lung T cells bearing certain V beta transcripts and the T cell receptor (TCR) is internalised ... 1994) T cell receptor repertoire of T lymphocytes recovered from the lung and blood of patients with sarcoidosis. Am J Respir ...

https://thorax.bmj.com/content/53/10/871?ijkey=11e1b4e28ff0d5c843fccd53d583acb1dc327ea5&keytype2=tf_ipsecsha

The lesion is a suppurating granuloma that consists of histiocytes and giant cells, with neutrophils that accumulate in the ... Pulmonary sporotrichosis may contribute to declining pulmonary function in patients with COPD. ... center and that are surrounded by lymphocytes and plasma cells.. The fungal infection spreads from the initial lesion along ... Primary pulmonary infection (pulmonary sporotrichosis) is rare, as is direct inoculation into tendons, bursae, or joints. ...

https://emedicine.medscape.com/article/228723-overview

Plasma cell infiltration of the small intestine, recurrent pulmonary infections, and cellular immunodeficiency (Nezelof's ... The clinical spectrum of hepatic granuloma. South African Medical Journal, 60: , 691 ... Plasma cell infiltration of the small bowel: lack of evidence for a nonsecretory form of alpha-heavy chain disease. Gut, 26: , ... Gaucher's disease complicated by bleeding esophageal varices and colonic infiltration by Gaucher cells. American Journal ...

https://www.med.uc.edu/depart/intmed/divisions/digestive/directory/faculty-profile/Index/Pubs/gilinsnh

Ten years follow-up of pulmonary inflammatory pseudo-tumor ... presence of IgG4-positive plasma cells in Plasma Cell Granuloma ... IgG4-positive plasma cells in inflammatory pseudotumor (plasma cell granuloma) of the lung. Hum Pathol. 2005;36:710-717. [ ... Pulmonary IPT represents a distinct group of pathologies ranging from benign lesions as plasma cell granuloma to lesions with ... Key Words: Inflammatory pseudotumor, Anaplastic lymphoma kinase, Inflammatory myofibroblastic tumor, Plasma cells granuloma, ...

https://wjgnet.com/2307-8960/full/v5/i2/61.htm

Plasma Cell Granuloma, Pulmonary. *Pneumonia. *Pulmonary Alveolar Proteinosis. *Pulmonary Atelectasis. *Pulmonary Edema ... "Pulmonary Alveolar Proteinosis" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and ... Secondary pulmonary alveolar proteinosis: a confusing and potentially serious complication of hematologic malignancy. J Thorac ...

https://profiles.uchicago.edu/profiles/display/34684

More specifically, PCGs are a type of mass-forming lesion arising from the accumulation of polyclonal plasma cells surrounded in a swirling storiform orientation of fibrosis and spindle cell proliferation. (wikipedia.org)
Analyzing the changes that arise in the tissue associated with the mass-forming lesion has been found to be the most accurate and precise method for confirming the diagnosis of plasma cell granulomas. (wikipedia.org)
Right upper lobe nodule shows peripheral calcification and high Hounsfield unit enhancement, suggesting that the lesion is a calcified, benign pulmonary nodule. (medscape.com)
The lesion is a suppurating granuloma that consists of histiocytes and giant cells, with neutrophils that accumulate in the center and that are surrounded by lymphocytes and plasma cells. (medscape.com)

Plasma cell granulomas (PCGs) are uncommon, non-neoplastic lesions of unknown etiology and are considered an entity of IgG4-related diseases. (wikipedia.org)
The etiology of plasma cell granulomas is widely unknown, however, there are a few ideas on what causes the condition to develop. (wikipedia.org)
Gotway, MB 2009, ' The thoracic mass: An unusual etiology ', Clinical Pulmonary Medicine , vol. 16, no. 5, pp. 287-291. (elsevierpure.com)

Often biopsies that show no evidence of malignancy contain granulomas in varying stages of activity and type (including the so-called naked granulomas of sarcoidosis), or simply a carpet of pigmented macrophages. (basicmedicalkey.com)
The unknown antigen triggers a cell-mediated immune response that is characterized by the accumulation of T cells and macrophages, release of cytokines and chemokines, and organization of responding cells into granulomas. (msdmanuals.com)
The exaggerated immune response to repeated inhalation of these particles leads to infiltration and proliferation of activated pulmonary macrophages and lymphocytes, resulting in lymphocytic alveolitis and bronchiolitis with noncaseating granulomas. (cdc.gov)
This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR. (uchicago.edu)
A central area of necrosis (called geographic necrosis) is rimmed by lymphocytes, plasma cells, macrophages, and giant cells. (merckmanuals.com)
In addition, IL-1β through its induction of prostaglandin E2 could influence the cell death modality of Mtb-infected macrophages favoring an apoptotic over necrotic fate thus containing bacterial spread ( 7 , 10 - 13 ). (frontiersin.org)

Since plasma cell granulomas have the ability to occur at any site, even though they are uncommon, it should be included in differential diagnostics in regard to plasma cell neoplasms. (wikipedia.org)
For instance, the anterior mediastinum is the site of the thymus with its varied associated pathology from Hodgkin and non-Hodgkin lymphoma (NHL), to thymoma, to germ cell neoplasms. (basicmedicalkey.com)
Surgical resections of mediastinal contents are restricted in most cases to mass lesions in the anterior mediastinum with thymic-related neoplasms, the thymus gland in cases of myasthenia gravis or a germ cell neoplasm (which may or may not be associated with the thymus). (basicmedicalkey.com)

Pulmonary Fibrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
This graph shows the total number of publications written about "Pulmonary Fibrosis" by people in this website by year, and whether "Pulmonary Fibrosis" was a major or minor topic of these publications. (umassmed.edu)
Below are the most recent publications written about "Pulmonary Fibrosis" by people in Profiles. (umassmed.edu)
Contribution of Fetal, but Not Adult, Pulmonary Mesothelium to Mesenchymal Lineages in Lung Homeostasis and Fibrosis. (umassmed.edu)
Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. (umassmed.edu)
Smoking-associated fibrosis and pulmonary asbestosis. (umassmed.edu)

A solitary pulmonary nodule is defined as a discrete, well-marginated, rounded opacity less than or equal to 3 cm in diameter that is completely surrounded by lung parenchyma, does not touch the hilum or mediastinum, and is not associated with adenopathy, atelectasis , or pleural effusion . (medscape.com)
[ 1 ] Therefore, prompt diagnosis and management of early lung cancer manifesting as a solitary pulmonary nodule is the the best chance for cure. (medscape.com)
Generally, a pulmonary nodule must reach 1 cm in diameter before it can be identified on a chest radiograph. (medscape.com)
These lesions are often discovered asymptomatically but may present fever, chest pain, dyspnea, or hemoptysis-these latter 2 symptoms may be more frequently encountered in airway lesions.The imaging findings of thoracic IMT primarily consist of a solitary pulmonary nodule or mass, which may show calcification-this appearance, in a young patient, while not pathognomonic, suggests IMT.The margins of thoracic IMTs may be smoothly circumscribed or lobulated or poorly defined. (elsevierpure.com)
A benign pulmonary nodule can be caused by infectious granulomas and benign tumours such as a pulmonary hamartoma. (2011globalhealth.org)

Diagnosis usually is first suspected because of pulmonary involvement and is confirmed by chest x-ray, biopsy, and exclusion of other causes of granulomatous inflammation. (msdmanuals.com)
Patients were enrolled in the study if they fulfilled previously accepted clinical diagnostic criteria, 15 had evidence of non-caseating granulomas on biopsy specimens, a negative Mantoux test, and negative MTb cultures with no prior history of tuberculosis. (bmj.com)
Absence of plasma cells on biopsy. (primaryimmune.org)
A surgical biopsy showed an infiltrate of eosinophilic cells with oval, grooved and convoluted nucleus, associated with eosinophils, lymphocytes and plasma cells ( Figure 2 ). (scirp.org)
Noncaseating granulomas are present in biopsy samples in a number of cases. (medscape.com)

Unexplained ground glass opacities, interstitial lung disease, and/or pulmonary granulomas. (primaryimmune.org)
Microscopic polyangiitis (MPA) is a necrotizing vasculitis without granulomatous inflammation that predominantly affects small vessels (ie, capillaries, venules, or arterioles) and can present with pulmonary capillaritis or in the context of interstitial lung disease [ 3 ]. (medilib.ir)

Plasma cell granulomas are generally found to be benign, but in some cases, the granulomas have the ability to initiate malignancy and become symptomatic regardless of location or size. (wikipedia.org)
While plasma cell granulomas are often found to be benign, plasmacytomas have been associated with a more aggressive and invasive behavior in which they have the ability to transform or evolve into multiple myeloma. (wikipedia.org)
Plasma cell granuloma (PCG) is a rare benign tumor that is difficult to differentiate from malignancy. (diva-portal.org)
a Critical Images slideshow, for more information on benign and malignant etiologies of solitary pulmonary nodules. (medscape.com)
Most solitary pulmonary nodules are benign. (medscape.com)
Benign lung tumors are a heterogenous group of neoplastic lesions originating from pulmonary structures. (medscape.com)
Extramedullary plasmacytoma is an unusual mode of presentation for newly diagnosed myeloma patients, but in these unlucky cases the disease is often extensive, and the prognosis is poor.6 The causes of incidental pulmonary nodules can be categorised as benign or malignant. (2011globalhealth.org)

These lesions often show intense contrast enhancement and may even be associated with aberrant systemic arterial supply, resembling pulmonary sequestration.The treatment of choice for thoracic IMT is limited surgical resection, with corticosteroid therapy or radiation reserved for unresectable patients or patients with inadequate surgical margins. (elsevierpure.com)
Hypersensitivity pneumonitis, also known as extrinsic allergic alveolitis, is an uncommon non-immunoglobulin E (IgE), T-helper cell type 1 (Th1)-mediated inflam- matory pulmonary disease with systemic symptoms resulting from repeated inhalation and subsequent sensitization to a large variety of aerosolized antigenic organic dust particles. (cdc.gov)
We report a rare case of adult Langerhans cell histiocytosis in the dorsal spine causing a spinal cord compression associated with a pulmonary process treated by surgery, radiotherapy and systemic therapy with good evolution. (scirp.org)
In general, two different forms of GPA have been described: the localized form, usually limited to the upper airway, and the systemic form, with predominant renal and pulmonary involvement [ 1 ]. (ejao.org)

these observations, and the variable biological behavior of these lesions, make them difficult to properly classify.Pulmonary IMTs occur over a wide age range, but are most commonly encountered in children, adolescents, or young adults. (elsevierpure.com)
Neurologic disease may occur in a patient with hematocrit and red cell parameters within the reference range. (medscape.com)
Skin findings occur in about of patients with proven pulmonary emboli than complete anti-bodies and thus to decreased pulmonary perfu-sion in response to improved outcomes in adults. (elastizell.com)
Vasculitic lesions and disseminated granulomas occur only occasionally. (merckmanuals.com)
Oral granulomas may occur without characteristic alimentary involvement (orofacial granulomatoses). (medscape.com)

PCGs are characterized by the proliferation and infiltration of different inflammatory cells with the main cell observed in highest concentrations being plasma cells. (wikipedia.org)
Neoplastic lesions are characterized by the autonomous proliferation of cells without a response to the normal control mechanisms governing cell growth. (medscape.com)
blood transfusion), spinal cord, lung cancer (oncology), respiratory cancer, radiology Background Multiple myeloma is a malignant proliferation of plasma cells mostly affecting the bone marrow and commonly presents with anaemia, hypercalcaemia, renal dysfunction, bone and skeletal involvement. (2011globalhealth.org)
Langerhans cell histiocytosis is a rare disease involving clonal proliferation of langerhans cells seen in children and young adults. (scirp.org)

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control. (umassmed.edu)
IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Mycobacterium tuberculosis Infection. (umassmed.edu)
4 Where the organism is found in sarcoid-like granulomas, the diagnosis is usually considered to be tuberculosis. (bmj.com)
Caseating granulomas secondary to tuberculosis may be found in the absence of lung disease in patients who are malnourished, immunosuppressed, or alcoholic. (medscape.com)
Peripheral blood mononuclear cells from healthy donors were cultured with Mycobacterium tuberculosis and extracellular matrix in a 3D model of TB granuloma formation. (figshare.com)
Elevated levels of CTSB was observed in the lungs of mice and rabbits following infection with Mycobacterium tuberculosis (Mtb) H37Rv as well as in plasma from acute tuberculosis patients. (frontiersin.org)

Pulmonary symptoms range from none to cough, exertional dyspnea and, rarely, lung or other organ failure. (msdmanuals.com)
Cytoplasmic-ANCA (c-ANCA), perinuclear-ANCA (p-ANCA), and granulomas were analyzed against many ophthalmic signs and symptoms. (bvsalud.org)
Pulmonary symptoms include fatigue, exertional dyspnea, and non-productive cough. (rahulgladwin.com)

Challenges during repeat extracorporeal life support in a patient with pulmonary alveolar proteinosis. (uchicago.edu)
Secondary pulmonary alveolar proteinosis: a confusing and potentially serious complication of hematologic malignancy. (uchicago.edu)

Histopathological analysis of plasma cell granulomas have been found to be the most precise confirmative diagnosis to distinguish PCGs from other lesional tumors of plasma cell origins. (wikipedia.org)
This case illustrates how it is possible to utilize a technique used for cardiac surgery for tumors of pulmonary origin involving the heart. (diva-portal.org)
Once universally fatal, Pancoast tumors are currently treatable with outcomes similar to those of other stage-matched non-small cell lung cancers. (medscape.com)

Histologically, subacute HP is characterized by the presence of cellular bronchiolitis, noncaseating granulomas, and bronchiolocentric lymphocytic interstitial pneumonitis. (ajronline.org)

Patients with solitary pulmonary nodules are usually asymptomatic. (medscape.com)
However, solitary pulmonary nodules can pose a challenge to clinicians and patients. (medscape.com)
Conclusions: We recommend that clinicians should consider ocular or orbital GPA in patients presenting with non-specific eye complaints, such as vision impairment, orbital mass, or proptosis, and obtain further assessments to determine the possible presence of granuloma, c-ANCA, or p-ANCA. (bvsalud.org)
Pulmonary sporotrichosis may contribute to declining pulmonary function in patients with COPD. (medscape.com)
Investigations On admission the patients blood count was normal: haemoglobin 138 g/L, white cell count 5.14109/L with a normal differential and platelets 256109/L. Chemistry was normal with no evidence of renal failure or hypercalcaemia. (2011globalhealth.org)
HIV-1-infected TB patients had reduced pulmonary MMP concentrations, associated with reduced cavitation, but increased plasma PIIINP, compared to HIV-1-uninfected TB patients. (figshare.com)
CLINICAL FEATURES - Patients with granulomatosis with polyangiitis (GPA) typically have both upper airway and pulmonary involvement, although a minority may have just one or the other [ 1 ]. (medilib.ir)

Gaucher's disease complicated by bleeding esophageal varices and colonic infiltration by Gaucher cells. (uc.edu)
Findings include hilar adenopathy and pulmonary infiltration. (rahulgladwin.com)
They all share histologically a significant infiltration of affected tissues by langerhans cells. (scirp.org)

Microscopically, plasma cell granulomas, demonstrate a lesional pattern of inflammatory pseudotumor. (wikipedia.org)
The term inflammatory pseudotumor has previously been used to classify plasma cell granulomas. (wikipedia.org)

In large cell lymphoma and leukemia cells involvement of body fluid this concept becomes less challenging. (cytojournal.com)

Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening. (ouhsc.edu)
Single Stage Repair of Aortic Coarctation and Coronary Artery Bypass Grafting in a 55-Year- Old-Man Presenting with Pulmonary Edema. (ouhsc.edu)
An unusual case of unilateral pulmonary edema with contralateral bronchial obstruction. (ouhsc.edu)
Experimental interstitial pulmonary edema. (ouhsc.edu)
The radiologic manifestations of acute HP are those of acute pulmonary edema. (ajronline.org)

With granulomas that arise in the mouth, PCGs are commonly misclassified considering the malignancy of the disease due to its aggressive behavior and clinical presentation. (wikipedia.org)
It is imperative that such differentiation between plasma cell granuloma and plasmacytomas are completed prior to informing the patient undergoing clinical examination. (wikipedia.org)
Clinical Pulmonary Medicine , 16 (5), 287-291. (elsevierpure.com)
The clinical manifestations of autoimmune gastritis are primarily related to the deficiency in cobalamin, which is not adequately absorbed because of intrinsic factor (IF) deficiency resulting from severe gastric parietal cell atrophy. (medscape.com)

Crohn disease is an idiopathic disorder that can involve the entire GI tract with transmural inflammation, noncaseating granulomas, and fissures. (medscape.com)
Acute and chronic inflammation, with lymphocytic and giant cell perivascular infiltrates, and lymphoid follicles are the most common histologic findings in oral and GI Crohn disease. (medscape.com)

C. pulmonary artery catheter being used to measure cardiac output. (nursingessay24x7.com)

A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. (umassmed.edu)
A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. (uchicago.edu)
Alterations in pulmonary alveoli after a single injection of monocrotaline. (ouhsc.edu)

This form of sporotrichosis is most common in individuals with severe underlying chronic obstructive pulmonary disease (COPD) and alcoholism. (medscape.com)
Granulomatosis with polyangiitis (GPA) is a chronic and systematic autoimmune condition characterized by granuloma formation and necrotizing vasculitis of small to medium-sized vessels. (ejao.org)

A multisystem disease comprising of noncaseating granulomas found on various organs. (rahulgladwin.com)

Metastasis, usually a carcinoma of the lung or elsewhere (most often squamous cell carcinoma of the head and neck, papillary thyroid carcinoma, or renal cell carcinoma), accounts for over 50% of the diagnoses. (basicmedicalkey.com)
Squamous cell carcinoma occurs more frequently, although large cell and undifferentiated types are also common. (medscape.com)

Histologic findings in the juvenile alligators were multiorgan necrosis, heterophilic granulomas, and heterophilic perivasculitis and were most indicative of septicemia or bacteremia. (cdc.gov)

It consists of Langerhans cells with oval, grooved and convoluted nucleus and slightly eosinophilic cytoplasm, associated with eosinophils, lymphocytes and plasma cells (H & E × 400). (scirp.org)

Solitary extramedullary plasmacytoma (SEP) describes solid plasma cell tumours of soft-tissue origin as opposed to solitary plasmacytoma of bone. (2011globalhealth.org)

Differentiating between low-grade lymphoma and reactive lymphocytes is often difficult by morphology alone as reactive lymphoid cells may acquire activation morphology from being exposed to different cytokines within the body fluid. (cytojournal.com)

Others suggest that plasma cell granulomas have an autoimmune origin. (wikipedia.org)

The craniofacial and thoracoabdominal computed tomography (CT) -scans showed ethmoid and maxillary sinusitis, low facial bone density, multiple mediastinal and hilar lymphadenopathy, diffuse small pulmonary nodules, and hepatomegaly. (bvsalud.org)

Septal deviation in bold indicate renal plasma cells in the carer do not look after a breastfeeding is easy to duplication and hydrochlorothiazide 25 mg quick disolve. (newyorksecuritylicense.com)

Recurrent pulmonary infections particularly with unusual organisms. (primaryimmune.org)

Noncaseating granulomas are characteristic of orofacial Crohn disease. (medscape.com)

however, while strong suspicion about an NHL can be voiced in the case of a lymphoblastic lymphoma, both the large B-cell lymphoma and HL of the nodular sclerosis subtype have a considerable fibrous component, which may complicate the ability to obtain a sufficiently cellular FNA specimen for diagnosis. (basicmedicalkey.com)
The diagnosis of idiopathic isolated granulomatous gastritis is established only when known entities associated with granulomas are excluded. (medscape.com)
Final diagnosis was therefore Langerhans cell histiocytosis of the dorsal spine complicated by spinal cord compression. (scirp.org)

PCGs that manifest in the mouth, specifically the gingiva, have been seen to exhibit similar physical characteristics of other conditions such as epulis, fibroma, pyogenic granuloma, and peripheral giant cell granuloma. (wikipedia.org)

It has been noted that these granulomas have the propensity to manifest on any organ or soft tissue. (wikipedia.org)
In general, hematolymphoid cells manifest as dyshesive cells in cytological specimens. (cytojournal.com)

Occasionally, plasma cell granulomas are misdiagnosed as malignant lymphoma or malignant plasmacytoma during initial examination due to radiological evidence of its ability to erode and infiltrate bone. (wikipedia.org)
Large cell lymphoma and leukemia cells tend to have large size nuclei, less mature chromatin, and visible nucleoli with and without cytoplasmic vacuoles. (cytojournal.com)

Beryllium produces health effects ranging from sensitization without evidence of disease to clinically apparent pulmonary disease. (cdc.gov)
1 , 2 In addition, mRNA encoding the cytokines interleukin 2 (IL-2) and granulocyte macrophage colony stimulating factor (GM-CSF) are increased at sites of disease activity, suggesting local activation of antigen specific T cells. (bmj.com)
Pulmonary veno-occlusive disease. (ouhsc.edu)

This systematic review aimed to highlight the most common ophthalmic manifestations and to uncover their associations with antineutrophil cytoplasmic antibody (ANCA) positivity and the presence of granulomas. (bvsalud.org)

These specimens, commonly intrathoracic lymph nodes, are submitted for intraoperative frozen section consultation to ascertain their metastatic status for purposes of operability of a nonsmall cell carcinoma of the lung. (basicmedicalkey.com)

Primary pulmonary infection (pulmonary sporotrichosis) is rare, as is direct inoculation into tendons, bursae, or joints. (medscape.com)

By 3yrs old, up after vein occlusion, changes in capillary leak and pulmonary hypertension. (newyorksecuritylicense.com)

In immunohistochemical study, these eosinophilic cells expressed CD1a and S100 protein. (scirp.org)

The Association between Positive Tracheal Aspirate Cultures and Adverse Pulmonary Outcomes in Preterm Infants with Severe Bronchopulmonary Dysplasia. (jefferson.edu)

Anorexia with moderate weight loss that is occasionally associated with diarrhea may result from malabsorption associated with megaloblastic changes of the small intestinal epithelial cells. (medscape.com)

Sputum and plasma MMP concentrations were quantified by Luminex, plasma procollagen III N-terminal propeptide (PIIINP) by enzyme-linked immunosorbent assay, and urinary lipoarabinomannan (LAM) by Alere Determine TB LAM assay. (figshare.com)

Anatomy2

Diseases13

Interleukin-13 fusion cytotoxin arrests Schistosoma mansoni egg-induced pulmonary granuloma formation in mice. (1/31)

A case report of inflammatory pseudotumor of the lung: rapid recurrence appearing as multiple lung nodules. (2/31)

Pulmonary inflammatory pseudotumor--a report of 28 cases. (3/31)

Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts. (4/31)

Seven patients with plasma cell granuloma (inflammatory pseudotumor) of the lung, including two with intrabronchial growth: an immunohistochemical and electron microscopic study. (5/31)

Endobronchial pseudo-tumour caused by herpes simplex. (6/31)

A case of pulmonary inflammatory pseudotumor: Recurrence appearing as several consolidative lesions after complete resection. (7/31)

Endobronchial inflammatory pseudotumor: a case report. (8/31)

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Granuloma, Plasma Cell

Plasma Cell Granuloma, Pulmonary

Granuloma, Giant Cell

Gingival Diseases

Granuloma

Plasma Cells

Epithelioid Cells

Mandibular Diseases

Maxillary Diseases

Fibrous Dysplasia, Monostotic

Sarcoidosis

Leukemia, Plasma Cell

Granuloma, Foreign-Body

Granuloma, Pyogenic

Sarcoidosis, Pulmonary

Interleukin-13 fusion cytotoxin arrests Schistosoma mansoni egg-induced pulmonary granuloma formation in mice. (1/31)

A case report of inflammatory pseudotumor of the lung: rapid recurrence appearing as multiple lung nodules. (2/31)

Pulmonary inflammatory pseudotumor--a report of 28 cases. (3/31)

Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts. (4/31)

Seven patients with plasma cell granuloma (inflammatory pseudotumor) of the lung, including two with intrabronchial growth: an immunohistochemical and electron microscopic study. (5/31)

Endobronchial pseudo-tumour caused by herpes simplex. (6/31)

A case of pulmonary inflammatory pseudotumor: Recurrence appearing as several consolidative lesions after complete resection. (7/31)

Endobronchial inflammatory pseudotumor: a case report. (8/31)

Plasma cell granuloma - Wikipedia

West Nile Virus in Farmed Alligators - Volume 9, Number 7-July 2003 - Emerging Infectious Diseases journal - CDC

Resection of a plasma cell granuloma combining a conventional posterolateral left-sided thoracotomy with a minimally invasive...

Solitary Pulmonary Nodule: Background, Types of Benign Pulmonary Tumors, Etiology of Solitary Pulmonary Nodule

DeCS 2009 - Changed terms

DeCS 2009 - Changed terms

DeCS 2009 - Changed terms

DeCS 2009 - Changed terms

DeCS 2009 - Changed terms

DeCS 2009 - Changed terms

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DeCS 2009 - Changed terms

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Bio2Vec

Bio2Vec

Robin Kanagasabay - St. George's Aortic Team

Mediastinum | Basicmedical Key

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The thoracic mass: An unusual etiology<...

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Pulmonary Alveolar Proteinosis | Profiles RNS

Lesion4

Etiology3

Macrophages6

Neoplasms3

Fibrosis6

Nodule5

Biopsy5

Interstitial lung di2

Benign7

Systemic4

Occur5

Proliferation4

Tuberculosis6

Symptoms3

Alveolar proteinosis2

Tumors3

Bronchiolitis1

Patients7

Infiltration3

Pseudotumor2

Involvement1

Edema5

Clinical4

Inflammation2

Artery1

ALVEOLI3

Chronic2

Organs1

Squamous cell carc2