Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.
Starches that have been chemically modified so that a percentage of OH groups are substituted with 2-hydroxyethyl ether groups.
Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.
The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION.
Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.
Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.
A deficiency of blood coagulation FACTOR XIII or fibrin stabilizing factor (FSF) that prevents blood clot formation and results in a clinical hemorrhagic diathesis.
A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to form FACTOR XIIIA. It is important for stabilizing the formation of the fibrin polymer (clot) which culminates the coagulation cascade.
A complex of proteins that assemble the SNRNP CORE PROTEINS into a core structure that surrounds a highly conserved RNA sequence found in SMALL NUCLEAR RNA. They are found localized in the GEMINI OF COILED BODIES and in the CYTOPLASM. The SMN complex is named after the Survival of Motor Neuron Complex Protein 1, which is a critical component of the complex.
The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.
A method of tissue ablation and bleeding control that uses ARGON plasma (ionized argon gas) to deliver a current of thermocoagulating energy to the area of tissue to be coagulated.
The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.

Polymer structure and solubility of deoxyhemoglobin S in the presence of high concentrations of volume-excluding 70-kDa dextran. Effects of non-s hemoglobins and inhibitors. (1/379)

Earlier observations indicated that volume exclusion by admixed non-hemoglobin macromolecules lowered the polymer solubility ("Csat") of deoxyhemoglobin (Hb) S, presumably by increasing its activity. In view of the potential usefulness of these observations for in vitro studies of sickling-related polymerization, we examined the ultrastructure, solubility behavior, and phase distributions of deoxygenated mixtures of Hb S with 70-kDa dextran, a relatively inert, low ionic strength space-filling macromolecule. Increasing admixture of dextran progressively lowered the Csat of deoxyHb S. With 12 g/dl dextran, a 5-fold decrease in apparent Csat ("dextran-Csat") was obtained together with acceptable sensitivity and proportionality with the standard Csat when assessing the effects of non-S Hb admixtures (A, C, and F) or polymerization inhibitors (alkylureas or phenylalanine). The volume fraction of dextran excluding Hb was 70-75% of total deoxyHb-dextran (12 g/dl) volumes. Electron microscopy showed polymer fibers and fiber-to-crystal transitions indistinguishable from those formed without dextran. Thus when Hb quantities are limited, as with genetically engineered recombinant Hbs or transgenic sickle mice, the dextran-Csat provides convenient and reliable screening of effects of Hb S modifications on polymerization under near-physiological conditions, avoiding problems of high ionic strength.  (+info)

Resetting of exaggerated tubuloglomerular feedback activity in acutely volume-expanded young SHR. (2/379)

One purpose of the present study was to evaluate the ability of 7-wk-old spontaneously hypertensive rats (SHR) to reset tubuloglomerular feedback (TGF) activity in response to acute volume expansion (VE). Second, we evaluated the contribution of ANG II, via its action on AT1 receptors, to TGF control of glomerular function during VE. TGF was assessed by micropuncture methods and proximal tubular stop-flow pressure (SFP) determinations in SHR, Wistar-Kyoto rats (WKY), and Sprague-Dawley rats (SD). During euvolemia SHR exhibited enhanced TGF activity. In the same animals acute VE was achieved by infusion of saline (5 ml. h-1. 100 g body wt-1). VE led to resetting of TGF in all three strains. Maximal SFP responses, elicited by a 30-40 nl/min loop of Henle perfusion rate, decreased from 19 to 12 mmHg in SHR and, on average, from 11 to 5 mmHg in WKY and SD (P < 0.001). Tubular flow rate producing a half-maximal response (turning point) shifted to higher flow rates during VE, from 12 to 14 nl/min in SHR and from 15 to 19 nl/min in WKY. Administration of the AT1 receptor blocker candesartan (0.05 mg/kg iv) during sustained VE decreased TGF-mediated reductions in SFP in SHR and slightly increased the turning point in WKY. Nevertheless, other parameters of TGF activity were unaffected by AT1 receptor blockade. In conclusion, young SHR possess the ability to reset TGF activity in response to VE to a degree similar to compensatory adjustments in WKY. However, TGF remains enhanced in SHR during VE. ANG II and its action on AT1 receptors are in part responsible for the exaggerated SFP responses in young SHR during VE.  (+info)

Influence of right atrial pressure on the cardiac pacemaker response to vagal stimulation. (3/379)

We have recently shown that the intrinsic rate response to an increase in right atrial pressure is augmented when cardiac muscarinic receptors are activated. This present study examines the cardiac pacemaker response to vagal stimulation at different values of right atrial pressure in isolated rat right atrium and in the rabbit heart in situ. In the rat atrium, when pressure was raised in steps from 2 to 10 mmHg, there was a progressive reduction in the response to vagal stimulation [40.5 +/- 7.2% reduction (mean +/- SE) at 8 mmHg, P < 0.01], which was independent of the level of vagal bradycardia, that persisted in the presence of the beta-adrenergic agonist isoproterenol. In barbiturate-anesthetized rabbits with cervical vagi cut and beta-adrenergic blockade, raising right atrial pressure approximately 2.5 mmHg by blood volume expansion reduced the bradycardia elicited by electrical stimulation of the peripheral end of the right vagus nerve (9.1 +/- 1.1% reduction, P < 0.0001). These results demonstrate that vagal bradycardia is modulated by the level of right atrial pressure and suggest that normally right atrial pressure may interact with cardiac vagal activity in the control of heart rate.  (+info)

Effect of 20% in vitro haemodilution with warmed buffered salt solution and cerebrospinal fluid on coagulation. (4/379)

We have conducted an in vitro coagulation study consisting of two separate groups of 20 subjects using the thrombelastograph. In the first group, haemodilution was performed with a physiological balanced salt solution similar to plasma, with the exception of calcium, and buffered to a normal pH (Plasmalyte B) at 37 degrees C on blood obtained from consenting volunteers. In the second group, a protein-poor body fluid (cerebrospinal fluid (CSF)) obtained from parturient patients undergoing spinal anaesthesia for Caesarean section was used as the diluent. There were statistically significant differences between the warmed Plasmalyte B treated samples and their untreated controls for all variables measured by the thrombelastograph, except for maximum amplitude, and between the CSF treated samples and their untreated controls for all variables. We conclude that electrolyte and acid-base composition of the diluent fluid had no effect on the observation that crystalloid haemodilution produces hypercoagulability. The marked increase in coagulability produced by addition of CSF cannot be explained on a simple haemodilution basis and confirms previous suggestions of the presence of a procoagulant factor in CSF.  (+info)

Pseudo-proteinuria following gelofusine infusion. (5/379)

Transient massive proteinuria following cardiopulmonary bypass surgery was observed. It was characterized and attributed to post-operative gelofusine infusion. Gelofusine was found to interfere with dye binding but not immunochemical assays of proteinuria. Proteinuria following gelofusine infusion may not reflect underlying glomerular pathology.  (+info)

Effect of intravenous saline, albumin, or hydroxyethylstarch on blood volume during combined ultrafiltration and hemodialysis. (6/379)

It is generally advocated to use saline or albumin infusions during symptomatic hypotension during dialysis. However, because of their side effects and/or costs, they are of limited use. Hydroxyethylstarch (HES), a synthetic colloid with a long-standing volume effect, is used in the management of hypovolemia. In this study, the efficacy of three fluids (isotonic saline [0.9%], albumin [20%], and HES [10%]) was assessed during three treatment sessions with combined ultrafiltration and hemodialysis, which differed in the type of fluid given intravenously. Changes in relative blood volume (BV), systolic BP (SBP), and vascular reactivity (venous tone [VT]) were compared. An intravenous infusion of 100 ml of fluid was given when the decrease in BV versus baseline was more than 10% as measured by a continuous optical reflection method. The ultrafiltration was continued. BV decreased significantly versus baseline independent of the intravenous fluid administration in all three treatment sessions. However, when we compared BV values at the end of the dialysis session with those at the time of infusion, BV continued to decrease significantly with saline (change in BV -4.56 +/- 2.75%; P < 0.05) and albumin (change in BV -2.13 +/- 2.51%; P < 0.05), but not with HES (change in BV -0.15 +/- 2.17%; NS). Between albumin and HES there were no significant differences in changes in BV (NS), whereas between HES and saline (P < 0.05) and between albumin and saline (P < 0.05) the differences in BV changes were significant. SBP remained unchanged within each session. Although SBP tended to decrease more with saline compared to albumin and HES, the difference was not significant. The higher decrease in BV and SBP with saline was counterbalanced by a significantly higher increase in VT, while VT remained unchanged in the other two sessions. It is concluded that HES is a promising fluid in preserving blood volume, comparable to albumin, but superior to saline.  (+info)

Plasma volume expansion with solutions of hemoglobin, albumin, and Ringer lactate in sheep. (7/379)

We have measured plasma volume expansion (Evans blue and hematocrit changes) and hemodynamic responses in conscious hemorrhaged and normovolemic splenectomized sheep after a 30-min infusion of either 20 ml/kg of diaspirin cross-linked hemoglobin (DCLHb), 20 ml/kg of human albumin (Alb), or 60 ml/kg of a solution of Ringer lactate (RL). All regimens expanded blood volume and increased blood pressure and cardiac output after hemorrhage. However, only 15 +/- 3% of the infused volume of RL was evident as intravascular expansion 10-min postinfusion, compared with 67 +/- 16% and 139 +/- 139% for Alb and DCLHb, respectively. DCLHb infusions were associated with higher blood pressures and lower cardiac outputs compared with RL and Alb infusions, but the increased oxygen content of blood with DCLHb resulted in systemic delivery of oxygen similar to that of the other infusions. These differences in hemodynamics and vascular volume continued for 6 h, and at 24 h vascular volume and all hemodynamics were similar in all three groups. The better volume expansion with DCLHb may be due to greater mobilization of endogenous interstitial protein or reduced transcapillary loss as total intravascular endogenous plasma protein increased after infusion of DCLHb, whereas there was an apparent loss of endogenous intravascular protein after infusions of Alb and RL. Vasoconstriction by DCLHb is one mechanism that could lower blood-to-tissue transport of fluid and protein. In addition to its oxygen-carrying capacity and vasoactivity, DCLHb is associated with volume expansion properties out of proportion to its colloid osmotic pressure.  (+info)

Thrombelastogram reveals hypercoagulability after administration of gelatin solution. (8/379)

We have compared the effects of gelatin, low molecular weight hydroxyethyl starch (HES) or albumin on tests of haemostasis and on the thrombelastogram in 42 ASA I patients undergoing total hip or knee replacement. Patients were allocated randomly to receive one of the three blood substitutes to obtain moderate intraoperative haemodilution. Blood loss and packed red cell infusion was the same in each group. A greater amount of gelatin was given (1.5 times the measured blood loss) because of its shorter half-life. There was a statistically significant but clinically negligible decrease in platelets count, prothrombin time and fibrinogen, and an increase in bleeding time in all groups. Platelets were slightly but significantly lower after HES. Haemodilution was comparable between groups. TEG showed a state of hypercoagulability in the gelatin group with a significant decrease in r, r + k and an increase in alpha angle.  (+info)

Plasma substitutes are fluids that are used to replace the plasma volume in conditions such as hypovolemia (low blood volume) or plasma loss, for example due to severe burns, trauma, or major surgery. They do not contain cells or clotting factors, but they help to maintain intravascular volume and tissue perfusion. Plasma substitutes can be divided into two main categories: crystalloids and colloids.

Crystalloid solutions contain small molecules that can easily move between intracellular and extracellular spaces. Examples include normal saline (0.9% sodium chloride) and lactated Ringer's solution. They are less expensive and have a lower risk of allergic reactions compared to colloids, but they may require larger volumes to achieve the same effect due to their rapid distribution in the body.

Colloid solutions contain larger molecules that tend to stay within the intravascular space for longer periods, thus increasing the oncotic pressure and helping to maintain fluid balance. Examples include albumin, fresh frozen plasma, and synthetic colloids such as hydroxyethyl starch (HES) and gelatin. Colloids may be more effective in restoring intravascular volume, but they carry a higher risk of allergic reactions and anaphylaxis, and some types have been associated with adverse effects such as kidney injury and coagulopathy.

The choice of plasma substitute depends on various factors, including the patient's clinical condition, the underlying cause of plasma loss, and any contraindications or potential side effects of the available products. It is important to monitor the patient's hemodynamic status, electrolyte balance, and coagulation profile during and after the administration of plasma substitutes to ensure appropriate resuscitation and avoid complications.

Hydroxyethyl starch derivatives are modified starches that are used as plasma expanders in medicine. They are created by chemically treating corn, potato, or wheat starch with hydroxylethyl groups, which makes the starch more soluble and less likely to be broken down by enzymes in the body. This results in a large molecule that can remain in the bloodstream for an extended period, increasing intravascular volume and improving circulation.

These derivatives are available in different molecular weights and substitution patterns, which affect their pharmacokinetics and pharmacodynamics. They are used to treat or prevent hypovolemia (low blood volume) due to various causes such as bleeding, burns, or dehydration. Common brand names include Hetastarch, Pentastarch, and Voluven.

It's important to note that the use of hydroxyethyl starch derivatives has been associated with adverse effects, including kidney injury, coagulopathy, and pruritus (severe itching). Therefore, their use should be carefully monitored and restricted to specific clinical situations.

Hemodilution is a medical term that refers to the reduction in the concentration of certain components in the blood, usually referring to red blood cells (RBCs) or hemoglobin. This occurs when an individual's plasma volume expands due to the infusion of intravenous fluids or the body's own production of fluid, such as during severe infection or inflammation. As a result, the number of RBCs per unit of blood decreases, leading to a lower hematocrit and hemoglobin level. It is important to note that while hemodilution reduces the concentration of RBCs in the blood, it does not necessarily indicate anemia or blood loss.

In the context of medicine, plasma refers to the clear, yellowish fluid that is the liquid component of blood. It's composed of water, enzymes, hormones, antibodies, clotting factors, and other proteins. Plasma serves as a transport medium for cells, nutrients, waste products, gases, and other substances throughout the body. Additionally, it plays a crucial role in the immune response and helps regulate various bodily functions.

Plasma can be collected from blood donors and processed into various therapeutic products, such as clotting factors for people with hemophilia or immunoglobulins for patients with immune deficiencies. This process is called plasma fractionation.

Bone substitutes are materials that are used to replace missing or damaged bone in the body. They can be made from a variety of materials, including natural bone from other parts of the body or from animals, synthetic materials, or a combination of both. The goal of using bone substitutes is to provide structural support and promote the growth of new bone tissue.

Bone substitutes are often used in dental, orthopedic, and craniofacial surgery to help repair defects caused by trauma, tumors, or congenital abnormalities. They can also be used to augment bone volume in procedures such as spinal fusion or joint replacement.

There are several types of bone substitutes available, including:

1. Autografts: Bone taken from another part of the patient's body, such as the hip or pelvis.
2. Allografts: Bone taken from a deceased donor and processed to remove any cells and infectious materials.
3. Xenografts: Bone from an animal source, typically bovine or porcine, that has been processed to remove any cells and infectious materials.
4. Synthetic bone substitutes: Materials such as calcium phosphate ceramics, bioactive glass, and polymer-based materials that are designed to mimic the properties of natural bone.

The choice of bone substitute material depends on several factors, including the size and location of the defect, the patient's medical history, and the surgeon's preference. It is important to note that while bone substitutes can provide structural support and promote new bone growth, they may not have the same strength or durability as natural bone. Therefore, they may not be suitable for all applications, particularly those that require high load-bearing capacity.

Blood substitutes, also known as artificial blood or blood surrogates, are fluids that are designed to mimic some of the properties and functions of human blood. They are used as a replacement for blood transfusions in situations where blood is not available or when it is not safe to use. Blood substitutes can be divided into two main categories: oxygen-carrying and non-oxygen-carrying.

Oxygen-carrying blood substitutes contain artificial molecules called hemoglobin-based oxygen carriers (HBOCs) that are designed to carry oxygen from the lungs to the body's tissues. These HBOCs can be derived from human or animal hemoglobin, or they can be synthetically produced.

Non-oxygen-carrying blood substitutes, on the other hand, do not contain hemoglobin and are used primarily to restore intravascular volume and maintain blood pressure in cases of hypovolemia (low blood volume) caused by bleeding or dehydration. These products include crystalloids, such as saline solution and lactated Ringer's solution, and colloids, such as albumin and hydroxyethyl starch solutions.

It is important to note that while blood substitutes can be useful in certain situations, they are not a perfect substitute for human blood. They do not provide all of the functions of blood, such as immune defense and clotting, and their use is associated with some risks, including allergic reactions, kidney damage, and increased oxygen free radical production. Therefore, they should only be used when there is no suitable alternative available.

Factor XIII deficiency, also known as fibrin stabilizing factor deficiency, is a rare bleeding disorder caused by a lack or dysfunction of Factor XIII, a protein involved in the final stage of blood clotting. This deficiency results in impaired clot stability and increased risk of bleeding. Symptoms can include umbilical cord bleeding at birth, prolonged bleeding after circumcision, easy bruising, nosebleeds, muscle bleeds, gastrointestinal bleeds, and excessive menstrual bleeding. Treatment typically involves replacement of the missing Factor XIII through injections, either prophylactically or on-demand to manage bleeding episodes.

Factor XIII, also known as fibrin stabilizing factor, is a protein involved in the clotting process of blood. It is a transglutaminase enzyme that cross-links fibrin molecules to form a stable clot. Factor XIII becomes activated during the coagulation cascade, and its activity helps strengthen the clot and protect it from premature degradation by proteolytic enzymes. A deficiency in Factor XIII can lead to a bleeding disorder characterized by prolonged bleeding after injury or surgery.

The Survival Motor Neuron (SMN) complex is a protein complex that plays a crucial role in the biogenesis of small nuclear ribonucleoproteins (snRNPs), which are essential components of the spliceosome involved in pre-messenger RNA (pre-mRNA) splicing. The SMN complex consists of several proteins, including the SMN protein itself, Gemins2-8, and unrip.

The SMN protein is the central component of the complex and is encoded by the SMN1 gene located on chromosome 5q13.2. Mutations in this gene can lead to spinal muscular atrophy (SMA), a genetic disorder characterized by degeneration of motor neurons in the spinal cord, leading to muscle weakness and atrophy.

The SMN complex assembles in the cytoplasm and facilitates the assembly of spliceosomal snRNPs by helping to load Sm proteins onto small nuclear RNA (snRNA) molecules. Proper functioning of the SMN complex is essential for the correct splicing of pre-mRNA, and its dysfunction can lead to various developmental abnormalities and diseases, including SMA.

Hemostasis is the physiological process that occurs to stop bleeding (bleeding control) when a blood vessel is damaged. This involves the interaction of platelets, vasoconstriction, and blood clotting factors leading to the formation of a clot. The ultimate goal of hemostasis is to maintain the integrity of the vascular system while preventing excessive blood loss.

Argon Plasma Coagulation (APC) is a medical procedure that uses ionized argon gas to deliver electrical current and heat to tissue, resulting in coagulation. It is commonly used in the treatment of gastrointestinal bleeding, as well as for cutting and coagulating during surgical procedures. The argon plasma is created by passing argon gas through a high-voltage electrical field, which ionizes the gas and creates a highly precise and controllable plasma beam. This beam can be directed at the tissue to achieve hemostasis (stopping bleeding) or to cut tissue with minimal thermal damage to surrounding structures. The procedure is often performed under endoscopic guidance.

Blood coagulation, also known as blood clotting, is a complex process that occurs in the body to prevent excessive bleeding when a blood vessel is damaged. This process involves several different proteins and chemical reactions that ultimately lead to the formation of a clot.

The coagulation cascade is initiated when blood comes into contact with tissue factor, which is exposed after damage to the blood vessel wall. This triggers a series of enzymatic reactions that activate clotting factors, leading to the formation of a fibrin clot. Fibrin is a protein that forms a mesh-like structure that traps platelets and red blood cells to form a stable clot.

Once the bleeding has stopped, the coagulation process is regulated and inhibited to prevent excessive clotting. The fibrinolytic system degrades the clot over time, allowing for the restoration of normal blood flow.

Abnormalities in the blood coagulation process can lead to bleeding disorders or thrombotic disorders such as deep vein thrombosis and pulmonary embolism.

A blood plasma substitute may refer to: An artificially made substance designed to have one or more of the vast amount of ... This disambiguation page lists articles associated with the title Blood plasma substitute. If an internal link led you here, ... although providing volume is only one of many functions of blood plasma) ... functions of the contents of the blood plasma Volume expander ( ...
Campanini B, Raboni M (January 2003). "Oxygen Delivery by Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma ... Efaproxiral can be absorbed via transdermal, rectal, inhalation and gastrointestinal routes, though not at plasma ...
There is no substitute for blood. It must be voluntarily donated by one person to be given to another. The need for different ... blood components-red blood cells, platelets, and plasma-is constant. Donating on an ongoing basis helps ensure blood components ...
Albumin was an excellent substitute for human plasma in World War Two. When administered to wounded soldiers or other patients ... Human plasma proved to have several useful components other than albumin. Human blood plasma fractionation yielded human serum ... In heat ethanol, the plasma is heat treated at 68 degrees C with sodium octanoate with 9% ethanol at pH of 6.5. This results in ... Generally, if the yield is high, the purity is lowered, to roughly 85-90%. Cohn was able to start the Plasma Fractionation ...
He helped to develop bacterial polyglucose dextran as a blood plasma substitute. Stacey was awarded the Meldola Medal of the ...
Their areas of use have increased over time, partly substituting for other devices. A mobile convergence device is one that, if ... Convergent operating systems include the Linux operating systems Ubuntu Touch, Plasma Mobile and PureOS. Convergence can also ...
... and its use in a dextran-based blood plasma extender. This plasma substitute was used by medical personal in the Korean and ... a substance that replaced blood plasma in the Korean War. A member of the American Chemical Society, Jeanes published over 60 ...
Lactated Ringer's solution is another isotonic crystalloid solution and it is designed to match most closely blood plasma. If ... some oxygen-carrying blood substitutes are under development. ...
Meanwhile, Ferrari worked as a substitute teacher and the group donated plasma to fund their tours. The Pink Spiders also ...
Antihypertensive drugs and plasma lipids". Br Heart J. 66 (6): 409-410. doi:10.1136/hrt.66.6.409. PMC 1024812. PMID 1772705. ... Swales, J. D. (2 November 1991). "Salt substitutes and potassium intake". BMJ. 303 (6810): 1084-1085. doi:10.1136/bmj.303.6810. ... Arterial wall or plasma renin in hypertension?" (PDF). Clinical Science. 56 (4): 293-298. doi:10.1042/cs0560293. Archived from ...
Among the projects he worked on was a blood plasma substitute, of potential value to the military.) His Air Force time was ...
"2-Aminoindan and its ring-substituted derivatives interact with plasma membrane monoamine transporters and α2-adrenergic ... "alcoholic beverage substitute". In 2018, a company named Diet Alcohol Corporation of the Americas (DACOA) began openly ... "Alcoholic beverage substitutes", issued 2017-12-21 "Advisory - Health Canada warns consumers that Pace, promoted as an alcohol ... "Alcoholic beverage substitutes", published 2019-11-13 EP 3230255, Golan E, "Binge behavior regulators", published 2017-10-18 " ...
Rockets can be substituted for small nuclear missiles capable of destroying plasma bugs and wounding other large enemies. ... Plasma Bugs - The Bug artillery, they are bigger than the Tanker Bugs, and have the rather nasty ability to fire huge, volatile ... One of the roughneck missions was to attempt to capture a baby one alive so researchers could find out how this plasma is ... Their armored exoskeleton makes them impervious to everything except high explosives such as mini-nukes and plasma rockets. ...
Plasmapheresis, wherein blood is withdrawn and filtered, having the plasma removed and substituted, and returned to the patient ... a blood substitute solution of chemically modified human hemoglobin. Hemopure, a blood substitute solution of chemically ... Platelet factor 4 Fractions from blood plasma: Albumin Globulins Cryoprecipitate Cryosupernatant (cryo-poor plasma) Clotting ... This includes the use of red blood cells, white blood cells, platelets and blood plasma. Other fractions derived from blood are ...
... is a substituted tryptamine. It has two separate chiral centers, meaning that there are four different stereoisomers ... After ibogaine ingestion in humans, noribogaine shows higher plasma levels than ibogaine and is detected for a longer period of ... Both ibogaine and noribogaine have a plasma half-life of around two hours in the rat, although the half-life of noribogaine is ...
... plasma; and cryoprecipitate. Plasma derivatives are plasma proteins prepared under pharmaceutical manufacturing conditions, ... Blood products may also be called blood-based products to differ from blood substitutes, which generally refer to artificially ... This includes whole blood; blood components; and plasma derivatives. Whole blood is not commonly used in transfusion medicine. ... Cryoprecipitate Cryosupernatant Fresh frozen plasma PF24 Platelet transfusion Red blood cells The Clinical Use of Blood ...
Plasma substitutes Palmer's lab demonstrated that human serum albumin (PolyHSA) is able to resuscitate animals from hemorrhagic ... blood and plasma substitutes, and novel methods in protein purification, including interactions between adjacent cells Palmer ... "Therapeutic uses of the scavenging protein cocktail to treat plasma protein imbalances or depletion". Office of innovation and ... "for pioneering advances in engineering novel hemoglobin-based oxygen carriers for use as red blood cell substitutes in ...
"Plasma cholesteryl ester transfer protein activity is increased when trans-elaidic acid is substituted for cis-oleic acid in ... Elaidic acid increases plasma cholesterylester transfer protein (CETP) activity which lowers HDL cholesterol. Oleic acid Tardy ...
"Plasma cholesteryl ester transfer protein activity is increased when trans-elaidic acid is substituted for cis-oleic acid in ...
"Plasma cholesteryl ester transfer protein activity is increased when trans-elaidic acid is substituted for cis-oleic acid in ... Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the ... Okajima F (March 2002). "[Distribution of sphingosine 1-phosphate in plasma lipoproteins and its role in the regulation of the ...
Artificial Cells, Blood Substitutes, and Biotechnology Blood plasma substitute (disambiguation) Blood transfusion Bloodless ... Perfluorocarbon-based blood substitutes are completely man-made; this provides advantages over blood substitutes that rely on ... and non-human animal blood as blood substitute. Sir Christopher Wren suggested wine and opium as blood substitute. At the ... A blood substitute (also called artificial blood or blood surrogate) is a substance used to mimic and fulfill some functions of ...
However, detectable concentrations have been found in human breast cancer tissues and in pooled human blood plasma. Due to ... structural similarity, Sciadonic acid has shown potential as a substitute for arachidonic acid in cellular phospholipid pools ...
The name stems from the fact that it is methane (CH4) with a fluorine atom substituted for one of the hydrogen atoms. It is ... used in semiconductor manufacturing processes as an etching gas in plasma etch reactors. The compound is the lowest mass member ...
... acting as a substitute for the deuterium and tritium fuel capsules to be used later. Plasma Physics Group Leader Siegfried ... Due to the size of the test hohlraums, laser/plasma interactions produced plasma-optics gratings, acting like tiny prisms, ... They feature a small plastic ring around the "equator" of the target, which becomes a plasma when hit by the laser. Some of the ... Multiple laser beams heat the surface of the pellet into a plasma, which explodes away from the surface. The rest of the pellet ...
On the other hand, mammalian CPE synthase that is on the plasma membrane, SMS2, is a bifunctional enzyme that produces both CPE ... This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. ... and the other one is associated with the plasma membrane. The endoplasmic reticulum-resident CPE synthase, SMSr, is identified ... Sphingomyelin and ceramide-phosphoethanolamine synthesis by microsomes and plasma membranes from rat liver and brain. J. Lipid ...
Infected human red blood cells are incubated in a culture dish or flask at 37 °C together with a nutrient medium and plasma, ... Experimental studies on serum substitutes and supplements and alternative culture media for in vitro drug sensitivity assays ... serum or serum substitutes. A special feature of the incubation is the special gas mixture filled with Nitrogen (90-92 %) CO2 ( ...
Favorable characteristics in an NS5A inhibitor include high potency and long plasma half-life in order to achieve a once-daily- ... Symmetrical bis-imidazol structures, such as daclatasvir, experience a loss in potency when fluorene is substituted for the ... Additionally, it provides improved bioavailability and more favorable plasma half-life. There is also a remarkable increase in ...
PVP was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, ... PVP was used as a plasma volume expander for trauma victims after the 1950s. It is not preferred as volume expander due to its ...
For instance, levels for screen format may be LED, LCD, or Plasma.[citation needed] Respondents are shown a set of products, ... Each example is similar enough that consumers will see them as close substitutes but dissimilar enough that respondents can ...
Ideally, this is achieved by isovolemia exchange transfusion of a plasma substitute with a colloid osmotic pressure (OP). A ... Typical values for the viscosity of normal human plasma at 37 °C is 1.4 mN·s/m2. The viscosity of normal plasma varies with ... Blood is composed of plasma and formed elements. The plasma contains 91.5% water, 7% proteins and 1.5% other solutes. The ... Hemodilution is the dilution of the concentration of red blood cells and plasma constituents by partially substituting the ...
A blood plasma substitute may refer to: An artificially made substance designed to have one or more of the vast amount of ... This disambiguation page lists articles associated with the title Blood plasma substitute. If an internal link led you here, ... although providing volume is only one of many functions of blood plasma) ... functions of the contents of the blood plasma Volume expander ( ...
Dextran 10 has traditionally been used in infusion fluid and volume expander products.
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The Effects Of Substituting Spray-Dried Whole Egg From Egg Grading Plants For Spray-Dried Plasma Protein In Pase I Diets. ... Up to 50% (3.5% of the diet) of spray-dried plasma protein can be replaced with spraydried whole egg (6% of the diet) without ... A study was conducted to evaluate the effects of replacing spray-dried plasma protein with spray-dried whole egg from egg ...
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Ocean Plasma Blood Substitute. 2/3 water, 1/3 Seawater. 08/04/17. ...
Global Plasma Expressor Machine Market Report 2022 comes with the extensive industry analysis by Introspecti ... 4.1.3 Threat of Substitutes. 4.1.4 Competitive Rivalry. 4.1.5 Bargaining Power Among Buyers. 4.2 Industry Value Chain Analysis ... By Type, Plasma Expressor Machine market has been segmented into:. Manual Plasma Expressor. Automatic Plasma Expressor. By ... By Type, Plasma Expressor Machine market has been segmented into:. Manual Plasma Expressor. Automatic Plasma Expressor. By ...
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The importance of the plasma coagulation system in protecting life and preventing further blood loss following transection of a ... serum may be substituted for plasma in the test ... Plasma FXIII has a long half-life of approximately 9-14 days. A ... 24, 25] Subunit B circulates in plasma as part of the tetramer A2 B2 and as a free B2 dimer; all of plasma subunit A is ... Cryoprecipitate and fresh frozen plasma (FFP) provide a source of FXIII for most patients. All plasma-derived products carry ...
blood or plasma substitute infusions.. Any of these could cause anaphylaxis. If you have a reaction, it is important to find ...
This method, as well as the cell attachment rate, proved the difference among the plasma polymers with different amounts of ... Our previously-obtained impressive results of highly increased C2C12 mouse myoblast adhesion to amine plasma polymers (PPs) ... For the serum-free tests, we substituted DMEM medium by DMEM-F12 medium (Gibco) and FBS by ITS supplement (containing insulin, ... Cyclopropylamine plasma polymers for increased cell adhesion and growth. Plasma Process. Polymers. 14(7), 1600123 (2017). ...
Additionally, the slow degradation of high molecular weight or highly substituted HES may increase plasma osmotic pressure, ... Anaphylactoid reactions to colloid plasma substitutes: incidence, risk factors, mechanism. A French multicenter prospective ... Plasma substitution with 3% dextran-60 in orthopaedic surgery: influence on plasma colloid osmotic pressure, coagulation ... Adequate plasma volume is essential in maintaining cardiac output and hence tissue perfusion. The stable hemodynamic status of ...
Egg white, used as a substitute, was not as effective as cow plasma. The demand for a better substitute led to studies on the ... Even in modern times, blood still has use as an egg substitute. In World War II, Germans used blood plasma instead of eggs for ... 2005), ham pates were made that used cow globin, plasma, or both as a fat substitute. These were judged by a panel of 25 people ... Though blood plasma is generally treated as the most useful part of the blood, both plasma and hemoglobin seem like good raw ...
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Platelet-rich plasma. This substitute has a low infection rate but is not strong enough to be a stand-alone bone substitute. ... Conversely, some substitutes re-absorb too slowly, which can cause inflammation.. Biological substitutes. Share on Pinterest. ... Polymer-based substitutes. Doctors do not generally use polymer-based bone substitutes as bone grafts, as they do not promote ... These bone substitutes can be biological (natural) or synthetic.. Substitutes need to have several specific properties to be ...
The plasma is removed. Then, fresh plasma or a plasma substitute is added back to the blood. ... The machine separates the blood cells and plasma. The blood cells are then mixed with fresh plasma or a plasma substitute. The ... Plasmapheresis is a procedure to exchange plasma in the blood. Plasma is the liquid part of the blood. It does not have any ... Plasma Exchange; Therapeutic Plasma Exchange). How to Say It: plaz-mah-fer-EE-sis ...
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There was no association between maximal weight loss and plasma sodium concentration (p=0.807). Relative to non-drug exposed ... Among 354 term, substitute methadone-exposed infants, median maximal weight losses were 10.2% and 8.5% for breast- and formula- ... Postnatal weight loss in substitute methadone-exposed infants: implications for the management of breast feeding ... Postnatal weight loss in substitute methadone-exposed infants: implications for the management of breast feeding ...
It then replaces the harmful plasma with normal plasma or a plasma substitute. ... The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care ... Plasmapheresis. In this procedure, a special machine is used to remove harmful antibodies from plasma, the liquid part of the ...
Plasma TMAO, methionine, betaine, and dimethylglycine (DMG) were quantified by stable isotope dilution liquid chromatography ... Plasma carotenoids, lutein, and zeaxanthin were measured using reversed-phase high-performance liquid chromatography. There ... Following egg intake, the observed increases in plasma lutein and zeaxanthin may suggest additional protection against ... and plasma carotenoids lutein and zeaxanthin in MetS. This randomized, controlled crossover clinical trial included 23 subjects ...
These devices should never be substituted for seeing a medical professional for any type of health conditions.. Gloria Flores. ... Plasma is created when gas is charged with enough energy to convert it from gas to plasma. Plasma is what the sun is made of ... "plasma energy spheres" which create a plasma energy field that people can sit into to absorb the plasma energy. Products like ... Plasma spheres and plasma-based technology products are also going down in price and start at just $3,500. For more information ...
... or from hydrolysis of plasma triglycerides (TGFAs) form comm ... Substituting Rd using equation 1 gives: \[\mathrm{FCR}{=}\ ... Plasma analysis.. TG, FA, and glucose were determined in plasma as previously described (20). Lipids were extracted from plasma ... Accordingly, the data on plasma FA oxidation include the contribution of unlabeled plasma TG-derived FAs to the plasma FA pool ... 2 and 3 indicates that most of the [3H]TG label entered plasma as [3H]FA. This is caused by the very rapid turnover of plasma ...
PVP was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, ... PVP was used as a plasma volume expander for trauma victims after the 1950s. It is not preferred as volume expander due to its ...
There was no association between maximal weight loss and plasma sodium concentration (p=0.807). Relative to non-drug exposed ... Dryden, C. and Young, David and Campbell, N. and Mactier, H. (2012) Postnatal weight loss in substitute methadone-exposed ... Among 354 term, substitute methadone-exposed infants, median maximal weight losses were 10.2% and 8.5% for breast- and formula- ... Postnatal weight loss in substitute methadone-exposed infants: implications for the management of breast feeding ...
Dosage as a Substitute for Oral Nicardipine Therapy. The intravenous infusion rate required to produce an average plasma ... Total plasma clearance (Cl) is 0.4 L/hr·kg, and the apparent volume of distribution (Vd ) using a non-compartment model is 8.3 ... Plasma concentrations increase at a much slower rate after the first few hours, and approach steady state at 24 to 48 hours. On ... Rapid dose-related increases in nicardipine plasma concentrations are seen during the first two hours after the start of an ...
The effect of metformin, a dimethyl-substituted biguanide, known to lower plasma insulin and PAI-1 levels in vivo was ... The cellular origin of plasma PAI-1 in insulin resistance is not known. The hepatoma cell line Hep G2 has been shown to ... High plasma plasminogen activator inhibitor-1 (PAI-1) activity is associated with insulin resistance and is correlated with ...
... antibodies for COVID-19 and other infectious diseases that could be more potent and easier to supply than convalescent plasma. ... GigaGen aims to overcome supply limits, boost potency with recombinant convalescent sera substitute. Plus SAB gets additional ...
  • Spray-dried plasma protein concentrates are one-third the cost of spray-dried egg whites. (listverse.com)
  • Fresh whole blood has long been thought of as the criterion standard for transfusion, but the advent of whole blood fractionation techniques subsequent to World War II provided a means of more efficient use of the various components (i.e., packed red blood cells [PRBCs], fresh frozen plasma [FFP], individual factor concentrates, platelet concentrates, cryoprecipitate). (medscape.com)
  • The present invention relates to a family of S-substituted quinazoline derivatives that inhibitors of the enzyme phosphodiesterase 7 (PDE7), useful for the treatment or prevention of diseases mediated by said enzyme, especially inflammatory, neurodegenerative, neurological, psychiatric and/or autoimmune diseases. (justia.com)
  • The present invention relates to a family of S-substituted quinazoline derivatives that have selective or specific inhibitory activity of the enzyme phosphodiesterase 7 (PDE7), without significantly inhibiting other phosphodiesterases such as the enzyme phosphodiesterase 4 (PDE4). (justia.com)
  • The S-substituted quinazoline derivatives of the present invention are, therefore, useful for the treatment or prevention of diseases mediated by said enzyme PDE7, especially inflammatory, neurodegenerative, neurological, psychiatric and/or autoimmune diseases. (justia.com)
  • The inventors of the present patent, after extensive and exhaustive research, have surprisingly discovered a family of S-substituted quinazoline derivatives that have selective or specific inhibitory activity of the enzyme phosphodiesterase 7 (PDE7), without significantly inhibiting other phosphodiesterases such as the enzyme phosphodiesterase 4 (PDE4). (justia.com)
  • Blood derivatives and substitutes : preparation, storage, administration and clinical results including a discussion of shock , etiology, physiology, pathology and management / by Charles Stanley White and Jacob Joseph Weinstein. (who.int)
  • Because there's no substitute for blood, the blood supply used for transfusion must be donated . (kidshealth.org)
  • This narrative review delves into the intricate relationships between Hcy, vitamin B metabolites, dopamine-substituting compounds, and various symptoms of PD. (lu.se)
  • 3 Blood products are defined as any therapeutic substances derived from human blood, including whole blood, labile blood components and plasma-derived medicinal products. (who.int)
  • Available at: https://www.dynamed.com/procedure/therapeutic-plasma-exchange. (epnet.com)
  • To require the Commissioner of Public Health to grant a waiver to clinical laboratories to conduct blood plasma collection prior to licensure. (ct.gov)
  • Blood-borne transmission of pathogens has highlighted the crucial importance of effective policies, strategies, quality systems, and legislative and regulatory frameworks in the collection, testing, processing and supply of blood components, such as red cells, platelets and plasma, for clinical use. (who.int)
  • and these suggested doses and/or guidelines are not a substitute for clinical judgment. (globalrph.com)
  • Conversely, some substitutes re-absorb too slowly, which can cause inflammation . (medicalnewstoday.com)
  • We previously demonstrated that intake of three eggs/d for 4 weeks increased plasma choline and decreased inflammation in subjects with metabolic syndrome (MetS). (mdpi.com)
  • 6). Lung tissue, bronchoalveolar lavage fluid (BALF) and plasma were analyzed for cellular inflammation, cytokines, immunoglobulin E and heme oxygenase-1 (HO-1) expression. (cdc.gov)
  • All procedures have a minimum sample requirement, along with any alternate acceptable samples (i.e., substituting plasma for serum). (crlcorp.com)
  • The test may be performed by mixing the patient's plasma, serum, or serous effusions as a source of LE factor with bone marrow from a donor subject. (medscape.com)
  • There is controversy over the extent to which fatty acids (FAs) derived from plasma free FAs (FFAs) or from hydrolysis of plasma triglycerides (TGFAs) form communal or separate pools and what the contribution of each FA source is to cellular FA metabolism. (diabetesjournals.org)
  • The transport of fatty acids (FAs) in plasma occurs in two ways: via (albumin-bound) free FAs (FFAs) and via triglycerides (TGs) that are transported in TG-rich lipoproteins. (diabetesjournals.org)
  • Researchers found avocado consumption (1 to 1.5 per day) significantly reduced total cholesterol (TC), "bad" low density lipoprotein cholesterol (LDL-C) and triglycerides (TG) when they were substituted for sources of saturated fat. (scienceblog.com)
  • The research, "Impact of avocado-enriched diets on plasma lipoproteins: A meta-analysis," conducted at the University of the Pacific and independently funded , looked at 10 unique avocado studies with 229 participants, assessing the impact of avocados on cholesterol levels. (scienceblog.com)
  • HAB recently created a series of simple, quick to prepare interactive meal makeovers to show people how to make small shifts in their diets by substituting fresh avocados for other foods or ingredients higher in saturated fats. (scienceblog.com)
  • This experiment was conducted to study on general physiological changes, animal welfare behavior and productivity of Whole Cotton Seed (WCS) substitute in diets for Pon-Yang-Kham fattening beef cattle production. (scialert.net)
  • Sometimes red blood cells are specially prepared (washed) so they can be given to people who have had severe reactions to plasma. (msdmanuals.com)
  • The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Plasma Expressor Machine market in 2020. (bharatbook.com)
  • The effects of nicardipine on blood pressure significantly correlate with plasma concentrations. (nih.gov)
  • Washed red blood cells are free of almost all traces of plasma, most white blood cells, and platelets. (msdmanuals.com)
  • For more than 100 years, people have looked for a blood substitute without blood's limitations. (listverse.com)
  • People who have hemophilia , a disease that affects the blood's ability to clot, need plasma or the clotting factors contained in plasma to help their blood clot and prevent bleeding. (kidshealth.org)
  • GigaGen is developing polyclonal antibodies for COVID-19 and other infectious diseases that could be more potent and easier to supply than convalescent plasma. (biocentury.com)
  • We screened the potential anti-adhesive properties of a group of substituted dextrans, previously shown to exhibit potent anticoagulant and anticomplementary activities. (unige.ch)
  • These bone substitutes can be biological (natural) or synthetic. (medicalnewstoday.com)
  • Substitutes need to have several specific properties to be suitable for bone grafts. (medicalnewstoday.com)
  • A bone substitute with similar gaps allows blood vessels to grow into the graft to supply nutrients and encourage new bone growth. (medicalnewstoday.com)
  • Substitutes that break down too quickly are not suitable for bone grafts, as they do not allow enough time for the new bone to grow. (medicalnewstoday.com)
  • Doctors typically use it as filler, rather than as a complete bone substitute. (medicalnewstoday.com)
  • This substitute has a low infection rate but is not strong enough to be a stand-alone bone substitute. (medicalnewstoday.com)
  • This substitute has a porous structure similar to spongy bone. (medicalnewstoday.com)
  • Doctors do not generally use polymer-based bone substitutes as bone grafts, as they do not promote new bone growth. (medicalnewstoday.com)
  • A surgeon will make an incision and then place the bone substitute in the damaged area. (medicalnewstoday.com)
  • It is used as a bio-engineering scaffold or bone graft substitute. (vigyanprasar.gov.in)
  • In some cases, MGRS can progress to multiple myeloma, which is a type of cancer that affects the plasma cells in the bone marrow. (articleinsider.com)
  • García-Bailo B, Da Costa LA, Arora P, Karmali M, El-Sohemy A, Badawi A. Plasma Vitamin D and Biomarkers of Cardiometabolic Disease Risk in Adult Canadians, 2007-2009. (cdc.gov)
  • Plasma Vitamin D and Biomarkers of Cardiometabolic Dise. (cdc.gov)
  • High plasma plasminogen activator inhibitor-1 (PAI-1) activity is associated with insulin resistance and is correlated with hyperinsulinemia. (jci.org)
  • The cellular origin of plasma PAI-1 in insulin resistance is not known. (jci.org)
  • The effect of metformin, a dimethyl-substituted biguanide, known to lower plasma insulin and PAI-1 levels in vivo was concomitantly evaluated. (jci.org)
  • Just a ten-minute treatment with low-temperature plasma supposedly destroys drug-resistant bacteria causing wound infections in rats. (healthjockey.com)
  • On an average, the plasma was apparently able to kill 90 percent of the bacteria infecting skin wounds in rats after ten minutes. (healthjockey.com)
  • Oral administration of the potassium salt remarkably improved the plasma glucose levels of female Zucker diabetic fatty rats at 1 mg/kg. (rcsb.org)
  • Moreover, it did not cause a plasma volume increase or a cardiac enlargement in Wistar-Imamichi rats, even at 100 mg/kg. (rcsb.org)
  • A blood plasma substitute may refer to: An artificially made substance designed to have one or more of the vast amount of functions of the contents of the blood plasma Volume expander (although providing volume is only one of many functions of blood plasma) This disambiguation page lists articles associated with the title Blood plasma substitute. (wikipedia.org)
  • In World War II, Germans used blood plasma instead of eggs for many foods. (listverse.com)
  • Depending on the type of cake and animal, blood plasma can fully or only partly replace egg ingredients. (listverse.com)
  • 4. Blood, plasma and substitutes. (gamutonline.net)
  • The liquid inside brooklyntbone can be used as a substitute for blood plasma. (blogspot.com)
  • It also increases the flow of urine and can be used as a blood plasma substitute because it is sterile, pyrogen free and does not destroy blood cells. (infolanka.com)
  • The red blood cells are separated from the fluid component of the blood (plasma) and from the other cellular components. (msdmanuals.com)
  • Our previously-obtained impressive results of highly increased C2C12 mouse myoblast adhesion to amine plasma polymers (PPs) motivated current detailed studies of cell resistance to trypsinization, cell proliferation, motility, and the rate of attachment carried out for fibroblasts (LF), keratinocytes (HaCaT), rat vascular smooth muscle cells (VSMC), and endothelial cells (HUVEC, HSVEC, and CPAE) on three different amine PPs. (nature.com)
  • The scaffold conversion from hydrophobic to hydrophilic post- plasma treatment providing better cell adhesion is another interesting attribute. (vigyanprasar.gov.in)
  • Recent data on cardiovascular device-centered infections suggest that some plasma and extracellular matrix proteins contribute to bacterial adhesion and colonization on biomaterials. (unige.ch)
  • 20%) adhesion inhibition at 1 mg/ml, dextrans increasingly substituted with carboxylic and benzylamide groups (CMBD) exhibited increasing anti-adhesive activities. (unige.ch)
  • Another category of substituted dextrans having a variable proportion (2-26%) of sulfonated benzylamide groups (CMBDS) produced active inhibition of S. aureus adhesion. (unige.ch)
  • Furthermore, the anti-adhesive activity was still expressed when substituted dextrans were preincubated with fibronectin-coated PMMA but washed away at the time when radiolabeled bacteria were added to the adhesion assay. (unige.ch)
  • Following infusion, nicardipine plasma concentrations decline tri-exponentially, with a rapid early distribution phase ((alpha)-half-life of 2.7 minutes), an intermediate phase ((beta)-half-life of 44.8 minutes), and a slow terminal phase ((gamma)-half-life of 14.4 hours) that can only be detected after long-term infusions. (nih.gov)
  • Rapid dose-related increases in nicardipine plasma concentrations are seen during the first two hours after the start of an infusion of nicardipine hydrochloride injection. (nih.gov)
  • Plasma concentrations increase at a much slower rate after the first few hours, and approach steady state at 24 to 48 hours. (nih.gov)
  • Substantially reduced plasma concentrations of atazanavir are expected if PPIs are coadministered. (medscape.com)
  • Our study Plasma Expressor Machine Market helps user to make precise decision in order to expand their market presence and increase market share. (bharatbook.com)
  • The hemoglobin in the blood is used to make the blood substitutes HemoTech and Hemopure, which have several advantages over whole blood. (listverse.com)
  • Surface modification of electrospun PCL scaffolds by plasma discharge is an efficient method to make them optically transparent under wet conditions. (vigyanprasar.gov.in)
  • It is assumed that cold plasmas with temperatures of 35-40°C make the technology an attractive option for treating infections. (healthjockey.com)
  • There was no association between maximal weight loss and plasma sodium concentration (p=0.807). (bmj.com)
  • In this model, TGFAs mix locally at the capillaries with plasma FFAs, where they would lead to an increase in the local FA concentration, and hence, FA uptake. (diabetesjournals.org)
  • 95%) in human plasma over a wide concentration range. (nih.gov)
  • Interaction between plasma corticosterone concentration and adrenocorticotropin-releasing stimuli in the rat: Evidence for the reset of an endocrine feedback control. (scialert.net)
  • A study was conducted to evaluate the effects of replacing spray-dried plasma protein with spray-dried whole egg from egg grading plants on starter pig performance. (porkgateway.org)
  • Up to 50% (3.5% of the diet) of spray-dried plasma protein can be replaced with spraydried whole egg (6% of the diet) without influencing performance of starter pigs. (porkgateway.org)
  • The medical application of materials mentioned above could benefit from plasma processing of material surfaces. (nature.com)
  • Plasma technology for surface modifications has many advantages compared to morphological and chemical treatments, such as low toxicity, short time of production, substrate independence and, if required, a negligible degradation of the original material. (nature.com)
  • Local ventilation should be instituted to control excessive emissions, respiratory protection should be used, fibrous glass insulation treated with resin materials and used to seal annealing furnace doors should be substituted with a safer material, undue exposure to isocyanates should be avoided when handling urethane foams, and continuous surveillance should be maintained on all radiography equipment. (cdc.gov)
  • If the equipment for buffy coat is unavailable, an untreated venous blood sample is left to clot (from 20-120 minutes) and the plasma removed. (medscape.com)
  • According to the researchers, the safety and efficacy tests of the plasma-treated PCL (pPCL) scaffolds have shown effective and better healing than HAM, considered the gold standard in scaffolds for tissue engineering. (vigyanprasar.gov.in)
  • The efficacy of low-temperature plasma torch was examined on bacterial species such as Pseudomonas aeruginosa and Staphylococcus aureus. (healthjockey.com)
  • Plasmapheresis takes out certain proteins from the plasma. (epnet.com)
  • We see many patients whose body pain returns when ingesting sugar substitutes, so our advice is to avoid them as much as possible. (caringmedical.com)
  • Avoid or substitute another drug for these medications when possible. (medscape.com)
  • Fresh avocado, as part of a balanced diet, and as a cholesterol-free substitute for solid fats, can help be part of the solution for maintaining normal cholesterol levels," says Nikki Ford, PhD, Director of Nutrition, Hass Avocado Board. (scienceblog.com)
  • The mechanism(s) by which FA released by LPL activity enters the underlying tissues, and the interaction of this process with plasma FFA, is controversial. (diabetesjournals.org)
  • The Plasma Expressor Machine Market Research report incorporate value chain analysis for each of the product type. (bharatbook.com)
  • Since they are pure hemoglobin, the blood substitutes don't need to be matched by blood type. (listverse.com)
  • Global Plasma Expressor Machine Market Report 2022 comes with the extensive industry analysis by Introspective Market Research with development components, patterns, flows and sizes. (bharatbook.com)
  • The report also calculates present and past market values to forecast potential market management through the forecast period between 2022-2028.This research study of Plasma Expressor Machine involved the extensive usage of both primary and secondary data sources. (bharatbook.com)
  • The data generated by conducting the primary and secondary research.The report covers detail analysis of driver, constraints and scope for new players entering the Plasma Expressor Machine market. (bharatbook.com)
  • A team of researchers led by Prof. Ashwini Agrawal and Prof. Manjeet Jassal, SMITA (Smart and Innovative Textile Materials) Research Lab, Department of Textile & Fibre Engineering, IIT Delhi, in collaboration with the team from AIIMS Delhi, led by Prof. Radhika Tandon, Department of Ophthalmology, have developed a biopolymer-based scaffold, PCL, as a substitute to HAM (Human Amniotic Membrane) for patients with limbal deficiency. (vigyanprasar.gov.in)
  • Theoretical and laboratory studies on current-driven electromagnetic instabilities have been a popular subject in plasma research [ 1 , 2 ]. (hindawi.com)
  • During my specialist training I started to research on a new plasma substitute - 3% dextran 60, which, after my dissertation in 1987 in Lund became the main blood loss replacement fluid (registered as Plasmadex®) together with erythrocyte concentrate until 2000. (lu.se)
  • 1 However, diet, weight loss and exercise will be of significant benefit to patients under treatment with Prolotherapy , Platelet Rich Plasma Therapy, or Stem Cell Therapy. (caringmedical.com)
  • however, the strength of the recommendation to treat should be based on the patient's willingness to accept therapy as well as the prognosis for AIDS-free survival as determined by the HIV RNA copy per mL of plasma and the CD4+ T cell count. (cdc.gov)
  • The machine separates the blood cells and plasma. (epnet.com)
  • The blood cells are then mixed with fresh plasma or a plasma substitute. (epnet.com)
  • The purpose of the current study was to further explore the effects of phosphatidylcholine (PC) provided by eggs versus a choline bitartrate (CB) supplement on the gut microbiota, trimethylamine N-oxide (TMAO) formation, and plasma carotenoids lutein and zeaxanthin in MetS. (mdpi.com)
  • Polycaprolactone (PCL) scaffolds prepared in IIT Delhi, and modified with plasma treatment, are found efficient. (vigyanprasar.gov.in)
  • The surface engineering of PCL surface via plasma treatment increased the transparency and biocompatibility. (vigyanprasar.gov.in)
  • The product, electrospun nanofiber, is in the form of thin sheets called a "mat", ready for plasma treatment. (vigyanprasar.gov.in)
  • To study various aspect of quantum plasma, numerous efforts have been made whose applications are ranges from plasmonic device applications to dense astrophysical plasmas [ 7 - 16 ]. (hindawi.com)
  • immunoglobulins) and clotting factors, which are sometimes separated from plasma. (msdmanuals.com)
  • For example, immunoglobulins and clotting factors may be prepared from plasma pooled together from many donors. (msdmanuals.com)
  • Dr. Svetlana Ermolaeva, lead researcher and colleagues note that the cold plasmas destroy bacteria by damaging microbial DNA and surface structures without being harmful to human tissues. (healthjockey.com)
  • Various fluid plasma models have been developed by introducing the quantum effects through quantum corrections. (hindawi.com)
  • At large scales, plasma is treated as an electrically conducting fluid and can be described by magnetohydrodynamics, while the situation has to be interpreted within the frame work of kinetic theory when microscopic scales are involved. (hindawi.com)
  • In these investigations, the researchers have focused on the linear dispersion effects of several low frequency modes and instabilities as a benchmark problem in quantum plasma. (hindawi.com)
  • This information is neither intended nor implied to be a substitute for professional medical advice. (epnet.com)
  • Emerging studies suggest a correlation between elevated plasma homocysteine (hcy) levels and the risk of atherosclerosis, vascular disorders, and neurodegenerative diseases, including Parkinson's disease (PD). (lu.se)
  • Selective peroxisome proliferator-activated receptor gamma (PPARγ) modulators are expected to be a novel class of drugs improving plasma glucose levels without PPARγ-related adverse effects. (rcsb.org)
  • In this paper, we have made an effort to examine the role of quantum diffraction associated with electrons in a dense, hot, and magnetized plasma and its effect on low frequency modes. (hindawi.com)
  • Then, fresh plasma or a plasma substitute is added back to the blood. (epnet.com)
  • Other people might need plasma or only certain parts of plasma. (kidshealth.org)
  • It was concluded that this contact free, painless plasma technology can probably be a better substitute to antibiotics. (healthjockey.com)
  • The transparency of the plasma-treated PCL is tested through a water droplet test. (vigyanprasar.gov.in)
  • Competitive analysis is the study of strength and weakness, market investment, market share, market sales volume, market trends of major players in the market.The Plasma Expressor Machine market study focused on including all the primary level, secondary level and tertiary level competitors in the report. (bharatbook.com)
  • PVP was used as a plasma volume expander for trauma victims after the 1950s. (wikipedia.org)
  • Total plasma clearance (Cl) is 0.4 L/hr·kg, and the apparent volume of distribution (V d ) using a non-compartment model is 8.3 L/kg. (nih.gov)