Podophyllum peltatum
Podophyllum
Rhizome
Podophyllin
Podophyllum peltatum possesses a beta-glucosidase with high substrate specificity for the aryltetralin lignan podophyllotoxin. (1/3)
A beta-glucosidase with high specificity for podophyllotoxin-4-O-beta-D-glucopyranoside was purified from the leaves of Podophyllum peltatum. The 65-kDa polypeptide had optimum activity at pH 5.0 and was essentially inactive at pH 6.5 or above. Maximum catalytic activity of this glucosidase was obtained at 45 degrees C, but the enzyme was not heat stable. This beta-glucosidase displayed higher substrate specificity for podophyllotoxin-4-O-beta-D-glucopyranoside than for the other lignans tested, and for the (1-->3) linkage of laminaribiose than for other glucosidic linkages. (+info)Podophyllum peltatum and observations on the Creek and Cherokee Indians: William Bartram's preservation of Native American pharmacology. (2/3)
Historians have examined the significant contributions John and William Bartram made to 18th- and 19th-century knowledge of indigenous North American flora. However, the Bartrams' contribution to medicinal botanical knowledge, particularly William Bartram's compilation of Indians' knowledge on the preparation and use of medicinal botanicals, is not well-known. In addition, while William Bartram's contemporaries relied on his accounts of medicinal botanicals, they rarely acknowledged Bartram or Indians in their own works. Contemporaries plagiarized Bartram's writings and used his exquisite illustrations to ornament their own publications. This paper reconstructs William Bartram's careful collection and recording of medicinal botanical knowledge that became part of late 18th- and early 19th-century American pharmacology, as well as provides evidence for 54 Bartram-identified indigenous species and the pirating of William Bartram's work by contemporaries. (+info)Taxonomy of mayapple rust: the genus Allodus resurrected. (3/3)
(+info)Podophyllum peltatum, also known as Mayapple or American mandrake, is a plant native to North America. It contains podophyllotoxin, a compound with medicinal properties. In traditional medicine, it has been used topically for the treatment of genital warts caused by human papillomavirus (HPV). However, its use is limited due to its toxicity and potential adverse effects if ingested or improperly applied. It's important to note that Podophyllum peltatum should only be used under the supervision of a healthcare professional.
Podophyllum is a botanical name that refers to a genus of plants in the family Berberidaceae. It's commonly known as Mayapple or American mandrake. The dried rhizome (underground stem) of Podophyllum peltatum, also known as Podophyllin, contains podophyllotoxin and other aryltetralin lignans, which have been used in medical preparations for their antineoplastic (anti-cancer) properties.
In modern medicine, podophyllotoxin is obtained through semi-synthesis and is used as a topical treatment for genital warts. It works by inhibiting the formation of microtubules, which are necessary for cell division, leading to the death of the infected cells.
Please note that Podophyllum products should only be used under the supervision of a healthcare professional due to their potential toxicity.
A rhizome is not typically used as a medical term, but it is a term borrowed from botany that has been adopted in some areas of medicine, particularly in psychiatry and psychotherapy.
In its original botanical sense, a rhizome is a horizontal stem of a plant that grows underground, often sending out roots and shoots from its nodes. This growth pattern is contrasted with that of a root system, which grows downward, and a stem system, which grows upward.
In psychiatry and psychotherapy, the term "rhizome" has been used as a metaphor to describe a non-hierarchical and decentralized approach to understanding mental processes and subjectivity. The rhizome model emphasizes the complexity, multiplicity, and interconnectedness of these processes, and rejects simplistic or reductionist explanations that focus on a single cause or origin. Instead, it encourages a more holistic and dynamic view of mental life, one that is open to multiple perspectives and interpretations.
It's important to note that the use of the term "rhizome" in this context is metaphorical and not medical in the strict sense. It is a way of thinking about mental processes and subjectivity that has been influenced by poststructuralist and feminist theories, among others.
Podophyllin is not typically used in modern medicine due to its potential toxicity and the availability of safer and more effective alternatives. However, historically it was used as a topical medication for the treatment of certain skin conditions such as genital warts. It's derived from the dried roots and rhizomes of Podophyllum peltatum (May apple or American mandrake) and Podophyllum emodi (Himalayan mayapple).
The medical definition of Podophyllin, according to the 30th edition of Dorland's Illustrated Medical Dictionary, is: "A brownish-yellow, resinous extract from the rhizomes and roots of Podophyllum peltatum L. (Berberidaceae) or P. emodi Wall., containing podophyllotoxin and other aryltetralin lignans. It has been used topically as a caustic for treatment of condylomata acuminata, but its use is limited because of potential systemic toxicity."
It's crucial to note that Podophyllin should only be applied by healthcare professionals due to the risk of adverse effects and toxicity. The more common formulation now used is podophyllotoxin, which comes in a purified form and has a lower risk of systemic toxicity compared to Podophyllin.
Podophyllum peltatum
Lois Clark
Northeastern coastal forests
Northeastern interior dry-mesic oak forest
Native American ethnobotany
Podophyllotoxin
Secoisolariciresinol dehydrogenase
Sinopodophyllum
Epipodophyllotoxin
Trillium sessile
Podophyllum
Etoposide
Chemotherapy
Teniposide
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Plant sources of anti-cancer agents
Forest farming
Euptoieta claudia
Indian apple
Apple (disambiguation)
List of MeSH codes (B06)
Umbrella plant
Devil's apple
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List of flora of North Carolina
Mandrake (disambiguation)
Podophyllum delavayi
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List of freshwater aquarium plant species
Podophyllum peltatum - Wikipedia
DailyMed - PODOPHYLLUM PELTATUM pellet
Podophyllum Peltatum - ABC Homeopathy
Podophyllum Peltatum fever and chill symptoms by Boericke - ABC Homeopathy
Podophyllum peltatum - 6X 1 | Boiron USA
Podophyllum peltatum Mayapple, Hog apple, Mandrake Z 4-9 - Heritage Flower Farm
Podophyllum-peltatum-mayapple-fl-Olbrich-2008-05-22-img 7265 | M Molvray & P Kores Photos
Lignan and nutrient concentrations in American Mayapple (Podophyllum peltatum L.) in the Eastern United States | College of...
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Botanicals in Dermatology: An Evidence-Based Review
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Search Use
Photo Asset | Mayapple | Appalachian Cove (S.C.) | NatureScene | Knowitall.org
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Mayapple4
- 2001. The developmental ecology of mycorrhizal associations in mayapple, Podophyllum peltatum, Berberidaceae. (wikipedia.org)
- 2000. The American mayapple revisited - Podophyllum peltatum - still a potential cash crop? (ox.ac.uk)
- a mayapple that we predict will soon be elevated to species status as Podophyllum boreale. (plantdelights.com)
- Podophyllum emodi and Podophyllum peltatum (mandrake and mayapple, respectively) contaminated herbal preparations (eg, Gentiana and clematis) in the 1980s and 1990s. (medscape.com)
Berberidaceae1
- Podophyllum peltatum is an herbaceous perennial plant in the family Berberidaceae. (wikipedia.org)
19991
- ASHS Press, Alexandria, VA. Ernest Small and Paul M. Catling (1999), "Podophyllum peltatum L. (May-apple)", Canadian Medicinal Crops, NRC Research Press Brunton LL et al. (wikipedia.org)
Deamii1
- Podophyllum peltatum f. deamii Raymond Rhodora 50: 18 (1948). (kew.org)
Herbaceous1
- A herbaceous member of the berberis family, from the north east of the United States, Podophyllum peltatum emerges in spring with its leaves folded downwards around a pale, fleshy stem. (ox.ac.uk)
Plants2
- Plants for a Future, retrieved 28 March 2015 "Podophyllum L.". Integrated Taxonomic Information System. (wikipedia.org)
- Podophyllum peltatum at USDA PLANTS Database Watson, M.A. and five others. (wikipedia.org)
Anapodophyllum2
Medicinal1
- Native Americans used Podophyllum for a wide variety of medicinal purposes and as an insecticide (D. E. Moerman 1986). (wildflower.org)
Preparations1
- The root of podophyllum peltatum ‑ U.S. Preparations: The powdered root. (doctorschar.com)
Forming dense1
- PODOPHYLLUM peltatum - Umbrella like leaves emerge in spring from rhizomes forming dense mats in damp shade. (klynnurseries.com)
Podophyllin1
- I am satisfied that a trial of a tincture of Podophyllum will satisfy any one that it is preferable to Podophyllin in general practice. (doctorschar.com)
Native1
- Unlike our native Podophyllum peltatum, Podophyllum versipelle ssp. (plantdelights.com)
Leaves1
- The exotic leaves of Podophyllum make it an excellent choice as a specimen plant or for a mass planting. (plantdelights.com)
Hexandrum2
- have large, round or broadly dissected, serrated leaves and white, cream to pale rose flowers, which are followed by ornamental, large, bright colored egg shaped fruits (especially Podophyllum hexandrum). (rareplants.es)
- The enzyme from the plants Sinopodophyllum hexandrum and Podophyllum peltatum catalyses the formation of a methylenedioxy-bridge. (enzyme-database.org)
Emodi3
- Extracto cáustico de las raíces del Podophyllum peltatum y P. emodi. (bvsalud.org)
- Caustic extract from the roots of Podophyllum peltatum and P. emodi. (bvsalud.org)
- Podophyllum emodi and Podophyllum peltatum (mandrake and mayapple, respectively) contaminated herbal preparations (eg, Gentiana and clematis) in the 1980s and 1990s. (medscape.com)
Genus3
- Unfortunately for us nursery folk, the taxomonists have been left to run amok with slide rule and DNA kit, and they have allocated most of the species to other genera, Dysosma , Pilea , and Sinopodophyllum , leaving just P. peltatum as the orphan of that genus, and as ever there is some debate about this. (rareplantfair.co.uk)
- Podophyllum ) is the only species of this genus and is from the mountain slopes and woods of the western Himalaya. (rareplantfair.co.uk)
- The other better known form of what was known as Podophyllum has now been moved to Dysosma , a genus I hadn't even heard of, until this taxonomic upheaval, which, depending on source, relates to these Chinese forms. (rareplantfair.co.uk)
Woodland1
- Podophyllum peltatum is from eastern United States and south eastern Canada, and is widespread in the woodland there. (rareplantfair.co.uk)
Podophyllotoxin3
- Podophyllum comprises several glycosides, the most toxic of which is podophyllotoxin. (nih.gov)
- Podophyllum is also used in Western medicine topically to treat warts, and chemical modifications of podophyllotoxin have been developed as anticancer agents (etoposide and teniposide). (nih.gov)
- Podophyllotoxin is the active agent, and its strength varies with the type of podophyllum resin used. (medscape.com)
Mayapple plant1
- Similarly, Native Americans often used the root extracts of the indigenous North American mayapple plant (podophyllum peltatum) as a laxative and for other disorders. (nih.gov)
Podo3
- Know Your Remedies: Podophyllum Peltatum (Podo. (homeopathyplus.com)
- Podophyllum Peltatum (Podo) is one of the remedies to consider for gastrointestinal upsets and prolapsing of the rectum or uterus. (homeopathyplus.com)
- Podophyllum peltatum (Podo. (homeopathyplus.com)
Pleianthum3
- aka: Dysosma pleiantha) Stunning is the only word to describe a mature specimen of the giant Chinese mayapple, Podophyllum pleianthum. (plantdelights.com)
- This deer-resistant, tropical-looking Podophyllum pleianthum also doesn't go dormant until fall, unlike our native species. (plantdelights.com)
- Podophyllum pleianthum prefers moist organic soils and good shade for best performance. (plantdelights.com)
Versipelle1
- Podophyllum versipelle ) and the variety 'Spotty Dotty' which due to recent micropropagation is now reasonably widely available. (rareplantfair.co.uk)
Mandrake Root1
- Mandrake Root also known as Podophyllum Peltatum or Indian Apple, or Mayapple. (thepaganwitch.com)
Resin1
- Podophyllum resin is a powdered mixture of resins removed from the May apple (mandrake) ( Podophyllum peltatum linne ). (medscape.com)
Symptoms1
- Below are the main rubriks (i.e strongest indications or symptoms) of Podophyllum Peltatum in traditional homeopathic usage , not approved by the FDA. (abchomeopathy.com)
Wildflower1
- Mayapple The mayapple plant's scientific name is Podophyllum peltatum and is part of my running Wisconsin wildflower collection. (nikkilynndesign.com)
Apple1
- ASHS Press, Alexandria, VA. Ernest Small and Paul M. Catling (1999), "Podophyllum peltatum L. (May-apple)", Canadian Medicinal Crops, NRC Research Press Brunton LL et al. (wikipedia.org)
Ingredient1
- Ba Jiao Lian has been implicated in a generalized toxicity marked by gastrointestinal, bone marrow, neurological and hepatic injury, which is believed to be due to podophyllum, a major ingredient in the herb. (nih.gov)
Mandragora1
- Mandragora Officinarium Mandragora - also called mandrake - (must not be confounded with Podophyllum Peltatum. (abchomeopathy.com)
American1
- American podophyllum contains a fourth the amount of Indian sources. (medscape.com)