Poroma
Sweat Gland Neoplasms
Acrospiroma
Adenoma, Sweat Gland
Two adjacent nodules on the leg. (1/6)
Poroma is a rare benign neoplasm (derived from the intraepidermal part of the eccrine or apocrine duct), which may clinically mimic malignant tumors such as (amelanotic) malignant melanoma and porocarcinoma. Histopathological examination is the key to the correct diagnosis, which is illustrated in the present case, in which a pigmented basal cell carcinoma and a poroma are in close proximity to each other. Despite a clinical differential diagnosis of melanoma, histopathology showed the typical characteristics of a poroma, a rare but much more favorable tumor. Histopathological features of poroma are discussed. (+info)Eccrine poromatosis associated with polychemotherapy. (2/6)
(+info)Unknown: Pedunculated nodule on the foot. Eccrine poroma. (3/6)
Eccrine poroma is a benign adnexal neoplasm composed of epithelial cells with poroid or distal ductal differentiation. We report a healthy 57-year-old woman with a 4-year history of an asymptomatic pedunculated nodule on the lateral border of the right foot that was proven to be an eccrine poroma by histopathologic examination. (+info)Multiple poromas in a bone marrow transplant recipient: A case report. (4/6)
A poroma is a benign epithelial neoplasm that most commonly presents as a solitary papule on the palm or sole. We report the case of a 25-year-old male, with a history of acute myelogenous leukemia, who developed multiple poromas on the feet. Poromatosis - the occurrence of multiple poromas - has been described in six adults and one child; it appears to be more prevalent in patients with a history of lymphoproliferative disorder or radiation exposure. (+info)Dermal duct tumor with prominent ductal and sebaceous differentiation. (5/6)
(+info)Pigmented eccrine poroma: report of an atypical case with the use of dermoscopy. (6/6)
(+info)A poroma is a type of benign skin tumor that originates from the intraepidermal sweat glands, specifically the eccrine glands. These tumors are typically slow-growing and can appear as small, flesh-colored to brown or black nodules or plaques on the skin. They are most commonly found on the soles of the feet, hands, and other areas with high concentrations of sweat glands.
Poromas can be further classified into several subtypes based on their clinical and histological features, including hidroacanthoma simplex, dermal duct tumor, and digital papillary adenoma. While poromas are generally benign, there is a small risk of malignant transformation in some cases. Treatment typically involves surgical excision of the tumor.
Sweat gland neoplasms are abnormal growths that develop in the sweat glands. These growths can be benign (noncancerous) or malignant (cancerous). Benign sweat gland neoplasms include hidradenomas and syringomas, which are usually slow-growing and cause little to no symptoms. Malignant sweat gland neoplasms, also known as sweat gland carcinomas, are rare but aggressive cancers that can spread to other parts of the body. They may cause symptoms such as a lump or mass under the skin, pain, swelling, and redness. Treatment typically involves surgical removal of the growth.
Acrospiroma is a rare, benign skin tumor that is characterized by the proliferation of sweat gland components. It is also known as hidradenoma or clear cell hidradenoma. The tumor typically appears as a solitary, slow-growing nodule on the skin, often found on the head, neck, or trunk.
Acrospiromas are believed to arise from the pluripotent cells of the eccrine sweat glands, and they can vary in size from a few millimeters to several centimeters in diameter. The tumor is usually well-circumscribed, mobile, and may be skin-colored, yellowish, or bluish in appearance.
Histologically, acrospiromas are composed of large, clear cells with distinct cell borders, arranged in sheets, nests, or cords. These cells have a high glycogen content, which gives them a clear or eosinophilic (pink) cytoplasm on hematoxylin and eosin staining.
Treatment of acrospiromas typically involves surgical excision, with a low risk of recurrence. Malignant transformation is rare but can occur in some cases, leading to the development of clear cell hidradenocarcinoma.
A sweat gland adenoma is a benign (non-cancerous) tumor that develops in the sweat glands. These glands are responsible for producing sweat to help regulate body temperature. When an adenoma forms in the sweat glands, it can cause a variety of symptoms depending on its size and location.
Sweat gland adenomas are relatively rare and can occur anywhere on the body where there are sweat glands. They typically appear as painless, slow-growing lumps or bumps under the skin. In some cases, they may cause excessive sweating, discomfort, or other symptoms if they press on nearby nerves or structures.
The exact cause of sweat gland adenomas is not fully understood, but they are thought to arise from abnormal growth and division of the cells that make up the sweat glands. Treatment options for these tumors may include surgical removal, depending on their size, location, and symptoms. If left untreated, some sweat gland adenomas may continue to grow and cause complications over time.
Eccrine glands are the most numerous type of sweat glands in the human body, found in virtually all skin locations. They play a crucial role in thermoregulation by producing a watery sweat that cools the body when it evaporates on the skin surface. These glands are distributed over the entire body, with a higher concentration on the soles of the feet, palms of the hands, and forehead.
Structurally, eccrine glands consist of two main parts: the coiled secretory portion located in the dermis and the straight duct that extends through the dermis and epidermis to reach the skin surface. The secretory portion is lined with a simple cuboidal epithelium, while the duct is lined with a simple squamous or low cuboidal epithelium.
Eccrine glands are stimulated to produce sweat by the activation of the sympathetic nervous system, particularly through the release of acetylcholine at the neuro-glandular junction. The sweat produced is primarily water with small amounts of electrolytes, such as sodium, chloride, and potassium. This composition helps maintain the body's electrolyte balance while facilitating heat loss during physical exertion or in hot environments.
Dermoscopy, also known as dermatoscopy or epiluminescence microscopy, is a non-invasive diagnostic technique used in dermatology to evaluate skin lesions, such as moles and pigmented skin tumors. This method involves the use of a handheld device called a dermoscope, which consists of a magnifying lens, a light source, and a transparent plate or immersion fluid that allows for better visualization of the skin's surface structures.
Dermoscopy enables dermatologists to examine the pigmented patterns, vascular structures, and other morphological features hidden beneath the skin's surface that are not visible to the naked eye. By observing these details, dermatologists can improve their ability to differentiate between benign and malignant lesions, leading to more accurate diagnoses and appropriate treatment decisions.
The primary uses of dermoscopy include:
1. Early detection and diagnosis of melanoma and other skin cancers, such as basal cell carcinoma and squamous cell carcinoma.
2. Monitoring the evolution of suspicious moles or lesions over time.
3. Assisting in the identification of various benign skin growths, like seborrheic keratoses, dermatofibromas, and nevi (moles).
4. Improving the diagnostic accuracy for infectious skin conditions, inflammatory processes, and other dermatological disorders.
Overall, dermoscopy is a valuable tool in the field of dermatology that enhances the clinician's ability to diagnose and manage various skin conditions accurately and effectively.
Poroma
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Sweat gland
Poroma - Wikipedia
Poroma: Background, Pathophysiology, Etiology
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Dermoscopy of a non-pigmented eccrine poroma | De Diego | Journal of Surgical Dermatology
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- MedoSpeciaEccrine20
- Eccrine or apocrine poroma? (medscape.com)
- Kakinuma H, Miyamoto R, Iwasawa U, Baba S, Suzuki H. Three subtypes of poroid neoplasia in a single lesion: eccrine poroma, hidroacanthoma simplex, and dermal duct tumor. (medscape.com)
- A case of an unusual eccrine poroma on the left forearm area. (medscape.com)
- Eccrine poroma (EP) is an uncommon benign tumor of intra-epidermal portion of sweat ducts, usually affecting palmoplantar area in middle-aged patients. (com.pk)
- Histopathologic studies confirmed eccrine poroma as final diagnosis. (com.pk)
- Hasan A, Nafie K, Monazea K, Othman A, Salem A, Ismail A. A rare case of recurrent eccrine poroma underlying gluteal abscess. (com.pk)
- Lim GH, Abd Rashid F, Wong A. Eccrine poroma of the nipple: the first reported case. (com.pk)
- Kalamkar C, Radke N, Mukherjee A, Radke S. Rare case of large eccrine poroma of the eyelid. (com.pk)
- Eyelid Eccrine Poroma: A Case Report and Review of Literature. (com.pk)
- Eccrine Poroma on the Scalp: A Case Report with MR Findings. (com.pk)
- Eccrine Poroma. (com.pk)
- Dermoscopy of eccrine poroma. (com.pk)
- Kuo HW, Ohara K. Pigmented eccrine poroma: a report of two cases and study with dermatoscopy. (com.pk)
- Eccrine poroma: a clinical-dermoscopic study of seven cases. (com.pk)
- Kang M-C, Kim S-A, Lee K-S, Cho J-W. A case of an unusual eccrine poroma on the left forearm area. (com.pk)
- Rastaghi F, Mehrolhasani N, Shamsi Meimandi S, Iranmanesh B. Rapidly growing pedunculated Eccrine Poroma on the neck: A case report. (com.pk)
- 1 First described in 1956, poroma was originally identified as a tumor originating from the eccrine sweat gland. (clinicaladvisor.com)
- According to several studies with long-term follow-up, Eccrine porocarcinoma (EPC) may appear with at least two potential cancerogenesis pathways: i) de novo creation or ii) transformation from a benign pre-existing poroma. (rroij.com)
- 4] Intraepidermal Eccrine Adenocarcinoma (IEA) is classified with several other lesions that share similar pathological form, including: eccrine acrospiroma, eccrine porocarcinoma, malignant eccrine poroma and malignant hidroacanthoma simplex, among others. (faoj.org)
- Intraepithelial form of eccrine poroma. (altmeyers.org)
Simplex3
- As currently viewed, there are 4 poroma variants based on their predominant cell types and extent of the their tumor tissues presence in the epidermis and dermis: 1) Hidroacanthoma simplex poromas are confined to the epidermis, i.e. uppermost layer of the skin. (wikipedia.org)
- It may arise de novo or develop from pre-existing poroma and hidroacanthoma simplex. (koreamed.org)
- Acrospiroma - An acrospiroma (also known as a Clear cell hidradenoma, Dermal duct tumor, Hidroacanthoma simplex, Nodular hidradenoma, and Poroma [1]:665) is a tumor of the distal portion of a sweat gland. (en-academic.com)
Benign adnexal neoplasm2
- A poroma is a benign adnexal neoplasm composed of epithelial cells that show tubular (usually distal ductal) differentiation. (medscape.com)
- Poroma is a benign adnexal neoplasm of the intraepidermal portion of the sweat gland duct, called the acrosyringium . (clinicaladvisor.com)
Tumor3
- The prevalence of poroma is not clearly defined, but it is regarded as a relatively rare tumor. (clinicaladvisor.com)
- Histologically, a poroma is a well-circumscribed tumor that arises in the lower epidermis and extends into the dermis. (clinicaladvisor.com)
- It's related to acrospiroma (also called poroma), a tumor of the distal part of the sweat gland. (facmedicine.com)
Adnexal1
- In contrast to some adnexal neoplasms of follicular lineage, poroma development has no established familial predilection. (medscape.com)
Porocarcinoma2
- [ 1 ] The malignant counterpart of a poroma is referred to as porocarcinoma. (medscape.com)
- Sebaceous differentiation in poroid neoplasms: report of 11 cases, including a case of metaplastic carcinoma associated with apocrine poroma (sarcomatoid apocrine porocarcinoma). (medscape.com)
Manifests2
- A poroma usually manifests as a solitary papule or nodule. (medscape.com)
- A poroma manifests clinically as a solitary, dome-shaped papule, plaque, or nodule that extrudes from a shallow depression and measures from a few millimeters to a few centimeters in diameter. (clinicaladvisor.com)
Dermoscopy1
- Eksomtramage T, Aiempanakit K. Poroma: A case report of pulsatile papule visualized on dermoscopy. (com.pk)
Forearm1
- Mantri MD, Dandale A, Dhurat RS, Ghate S. Pedunculated poroma on forearm: A rare clinical presentation. (com.pk)
Malignant1
- The risk of malignant transformation of a poroma is minimal and is thought to be similar to that of normal skin. (medscape.com)
Poroid1
- A poroma is a benign neoplasm that shows differentiation toward poroid (glandular ductal) cells. (medscape.com)
Report1
- Kurashige Y, Yamamoto T, Okubo Y, Tsuboi R. Poroma with sebaceous differentiation: report of three cases. (medscape.com)
Eccrine35
- Eccrine or apocrine poroma? (medscape.com)
- Kakinuma H, Miyamoto R, Iwasawa U, Baba S, Suzuki H. Three subtypes of poroid neoplasia in a single lesion: eccrine poroma, hidroacanthoma simplex, and dermal duct tumor. (medscape.com)
- A case of an unusual eccrine poroma on the left forearm area. (medscape.com)
- Göktay F, Güneş P, Akpolat ND, Ferhatoğlu ZA, Önenerk M. Periungual Eccrine Poroma Masquerading as Ingrown Toenails A Case Report with Dermoscopic Findings . (medscape.com)
- Altamura D, Piccolo D, Lozzi GP, Peris K. Eccrine poroma in an unusual site: a clinical and dermoscopic simulator of amelanotic melanoma. (medscape.com)
- Poroma: a review of eccrine, apocrine, and malignant forms. (nih.gov)
- Eccrine poroma is a rare benign tumour of the adult. (dermatologyjournal.net)
- The eccrine poroma is a rare tumor, the clinical aspect is very polymorphic, histology is essential in these cases to eliminate the malignant tumors. (dermatologyjournal.net)
- Histopathological examination was consistent with benign adnexal tumor eccrine poroma. (ijorl.com)
- Eccrine poroma: A clinical-dermoscopic study of seven cases. (ijorl.com)
- Eccrine Poroma on the Face: An Atypical Presentation. (ijorl.com)
- 1. Malignant eccrine poroma invading the parotid gland. (nih.gov)
- Malignant eccrine poroma]. (nih.gov)
- 3. [Malignant eccrine poroma--a rare occurrence]. (nih.gov)
- 4. [Dermoscopic features of eccrine poroma]. (nih.gov)
- 7. [Eccrine poroma of the scalp: A study of three cases]. (nih.gov)
- 8. Eccrine poroma in neck of a child--a rare presentation. (nih.gov)
- 11. Eccrine porocarcinoma (malignant eccrine poroma): a case report. (nih.gov)
- 12. Benign and malignant eccrine poroma--a flow cytometric comparison. (nih.gov)
- 13. [Malignant eccrine poroma presenting as a breast tumor]. (nih.gov)
- 15. Malignant eccrine poroma. (nih.gov)
- 16. [Pigmented eccrine poroma]. (nih.gov)
- 17. Malignant eccrine poroma. (nih.gov)
- 18. A single lesion showing features of pigmented eccrine poroma and poroid hidradenoma. (nih.gov)
- An occasional case report describes increased urinary excretion of 5-S-cysteinl dopa in a case of pigmented eccrine poroma of scalp [ 6 ]. (cdlib.org)
- Pigmented Eccrine Poroma: A stimulant of nodular melanoma. (cdlib.org)
- 6. Jin KM, Nogita T, Toyoda H, Kawashima M, Hidano A. Pedunculated pigmented eccrine poroma of the scalp with increased urinary excretion of 5-S-csteinyldopa. (cdlib.org)
- The malignant counterpart of an eccrine poroma is called an ECCRINE POROCARCINOMA . (nih.gov)
- It most often develops as a form of degenerative progression from a benign ECCRINE POROMA . (bvsalud.org)
- It has traditionally been regarded as of eccrine origin and has four types: intraepidermal poroma (hidroacanthoma simplex), poroma, dermal duct tumor, and poroid hidradenoma. (tmu.edu.tw)
- Epidermotropic eccrine carcinoma: a case combining features of eccrine poroma and Paget's dermatosis. (ijsurgery.com)
- Mishima Y, Morioka S. Oncogenic differentiation of the intraepidermal eccrine sweat duct: eccrine poroma, poroepithelioma and porocarcinoma. (ijsurgery.com)
- Eccrine porocarcinoma (malignant eccrine poroma): a clinicopathologic study of 69 cases. (ijsurgery.com)
- Akalin T, Sen S, Yücetürk A, Kandiloglu G. P53 protein expression in eccrine poroma and porocarcinoma. (ijsurgery.com)
- Hidroacanthoma simplex (HAS), also known as intraepidermal eccrine poroma, is a rare eccrine adnexal tumor that tends to be misdiagnosed as other types of benign skin tumor, including clonal seborrheic keratosis. (elsevierpure.com)
Hidroacanthoma simplex2
- As currently viewed, there are 4 poroma variants based on their predominant cell types and extent of the their tumor tissues presence in the epidermis and dermis: 1) Hidroacanthoma simplex poromas are confined to the epidermis, i.e. uppermost layer of the skin. (wikipedia.org)
- Intraepidermal Poroma (Hidroacanthoma Simplex) Versus Clonal Seborrheic Keratosis: Will GATA3 Immunohistochemistry Help in the Differential Diagnosis? (nih.gov)
Benign1
- Poroma refers to benign adnexal neoplasm derived from the terminal portion of the duct of sweat gland. (ijorl.com)
Dermal duct1
- This intradermal poroma (dermal duct tumor) shows a sharply circumscribed border at scanning magnification. (medscape.com)
Sebaceous3
- Kurashige Y, Yamamoto T, Okubo Y, Tsuboi R. Poroma with sebaceous differentiation: report of three cases. (medscape.com)
- Herein, we describe the rare coexistence of a poroma and a trichoblastoma arising in a sebaceous nevus. (nih.gov)
- C, which is the common mutation in sebaceous nevus, was detected in all three lesions (sebaceous nevus, poroma, and trichoblastoma). (nih.gov)
Epidermis1
- This juxtaepidermal poroma presents histopathologically in continuity with the epidermis, creating a seborrheic keratosis-like profile. (medscape.com)
Lesions1
- Our comparison of the mutational profile of 95 skin cancer-related genes in each of the three lesions newly revealed TP53 p.R158P in the poroma and NOTCH2 p.G329S in the trichoblastoma. (nih.gov)
Back1
- Late last week, they made their way back to Poroma LLG, continued the awareness and visited other schools, and donated a desktop each to the schools. (com.pg)
Skin1
- Next, to elucidate the potential second-hit mutations in the secondary poroma and trichoblastoma, we applied a panel sequencing for skin cancers that was newly developed in our institution. (nih.gov)