Pulmonary Sclerosing Hemangioma
Hemangioma
Histiocytoma, Benign Fibrous
Multiple sclerosing hemangiomas with a 10-year history. (1/12)
We report a case of multiple sclerosing hemangiomas arising in a 38-year-old woman. Computed tomography (CT) scans of the chest showed multiple small nodules in all lobes of the right lung. The nodule sizes ranged from a few millimeters to the largest of 3.1 cm, which was located in the right middle lobe. She underwent right middle lobectomy to confirm the histological diagnosis. The resected specimen revealed multiple sclerosing hemangiomas. We followed this patient by annual chest CT scans for 10 years and demonstrated that all residual nodules remained unchanged. This is the first report of stable multiple pulmonary sclerosing hemangiomas observed for such a long period. (+info)Sclerosing hemangioma of the lung: a benign tumour with potential for malignancy? (2/12)
Pulmonary sclerosing hemangioma represents a rare neoplasm with variable potential for progression. This case report of a 35-year-old female with left-sided thoracic pain. Computed tomography revealed a centrally located, well-circumscribed and partially calcified lesion. Intraoperative findings were suggestive of a carcinoid tumour. The tumour was completely removed by lobectomy followed by systematic lymphadenectomy. The histopathological analysis revealed a sclerosing hemangioma, a rare benign neoplasm. Sclerosing hemangiomas (SHs) are true neoplasms derived from alveolar pneumocytes. However, little data is available on the potential malignant behaviour, such as lymphnode metastases, local recurrence, and the appearance of SH's. Generally, wedge resection is justified in the majority of cases, but in cases of uncertain intraoperative diagnosis, anatomic resection with systematic lymphadenectomy is recommended. (+info)Gene expression and clonality analysis of the androgen receptor and phosphoglycerate kinase genes in polygonal cells and cuboidal cells in so-called pulmonary sclerosing hemangioma. (3/12)
The histogenesis of polygonal cells and cuboidal cells in so-called pulmonary sclerosing hemangioma remains unclear. To understand their histogenesis, polygonal and cuboidal cells were obtained from pulmonary sclerosing hemangioma tissue using a laser capture microdissection technique. Genomic DNA and total RNA were extracted and mRNA levels of cytokeratin, epithelial membrane antigen, vimentin, surfactant protein B, thyroid transcription factor-1, synaptophysin, and chromogranin-A were analyzed by RT-PCR. DNA was digested with the methylation-sensitive enzymes HhaI or HpaII, followed by nested PCR of the androgen receptor and phosphoglycerate kinase genes. Samples with polymorphisms were identified and a clonality analysis was performed. The cytokeratin, epithelial membrane antigen, and surfactant protein B genes were clearly expressed in cuboidal cells, while the vimentin and synaptophysin genes were clearly expressed and the epithelial membrane antigen gene was weakly expressed in polygonal cells. Thyroid transcription factor-1 was expressed in both cell types, while neither cell type expressed chromogranin-A. Clonality analysis showed the same loss of allele in both cell types (clonality ratio=0) or an unbalanced methylation pattern (clonality ratio<0.25). Polygonal and cuboidal cells in pulmonary sclerosing hemangioma exhibited a uniform pattern of monoclonality, indicating that both cell types are highly likely to originate from a common precursor. The differences in their morphological phenotype might result from their different mature status. (+info)Lessons learned from mistakes and deferrals in the frozen section diagnosis of bronchioloalveolar carcinoma and well-differentiated pulmonary adenocarcinoma: an evidence-based pathology approach. (4/12)
(+info)Pulmonary sclerosing hemangioma in a 21-year-old male with metastatic hereditary non-polyposis colorectal cancer: report of a case. (5/12)
(+info)A case of sclerosing hemangioma forming a pedunculated mass. (6/12)
We report our experience with an unusual case of sclerosing hemangioma (SH) that formed a pedunculated mass protruding into the thoracic cavity. A pulmonary tumor was found in a 60-year-old female during the medical examination. Computed tomography showed a 19 x 17-mm nodule with a clear border and smooth margin contiguous with the diaphragm in the right S8 segment. Uneven enhancement following contrast medium administration was observed. We performed a 3-port thoracoscopic wedge resection of the right lower lobe. We observed a yellow pedunculated tumor protruding from the diaphragmatic surface of the right lower lobe. The surface of the tumor was smooth and encapsulated. Microscopically, we diagnosed it as a SH. SHs usually exist adjacent to the visceral pleura, but rarely form pedunculated tumors protruding into the cavity as seen in this case. By thoracoscopic surgery, we successfully diagnosed and treated the patient in a minimally invasive manner. Since there have been reported cases of recurrence, we anticipate that periodic follow-up observations will be required. (+info)Microscopic sclerosing hemangioma diagnosed by histopathological examination after lung cancer surgery. (7/12)
A 44-year-old woman underwent surgery for lung cancer. Although preoperative computed tomography did not reveal a tiny nodule, pathological examination of the background lung showed that type II pneumocyte-like tumor cells grew papillary in an area of approximately 2.3 x 1.2 mm. This lesion exhibited hemorrhage, hemosiderosis, calcification, and varying degrees of fibrosis, leading to the diagnosis of sclerosing hemangioma. This is the first reported case of microscopic sclerosing hemangioma undetectable by chest computed tomography. (+info)Segmentectomy for giant pulmonary sclerosing haemangiomas with high serum KL-6 levels. (8/12)
(+info)Pulmonary sclerosing hemangioma is a rare, benign lung tumor of uncertain origin. It is also known as sclerosing pneumocytoma. This tumor primarily affects adults, with women being more commonly affected than men. The typical symptoms include cough, chest pain, and sometimes blood-streaked sputum. However, many cases are asymptomatic and discovered incidentally on chest imaging.
On histopathology, pulmonary sclerosing hemangioma is characterized by the presence of two types of cells: surface cells (similar to type II pneumocytes) and round cells (similar to mesenchymal cells). The tumor shows a variety of architectural patterns including solid areas, papillary structures, and hemorrhagic cavities.
The treatment of choice is surgical resection. Despite its benign nature, there have been reports of recurrence after incomplete resection. However, the prognosis after complete resection is excellent.
A hemangioma is a benign (noncancerous) vascular tumor or growth that originates from blood vessels. It is characterized by an overgrowth of endothelial cells, which line the interior surface of blood vessels. Hemangiomas can occur in various parts of the body, but they are most commonly found on the skin and mucous membranes.
Hemangiomas can be classified into two main types:
1. Capillary hemangioma (also known as strawberry hemangioma): This type is more common and typically appears during the first few weeks of life. It grows rapidly for several months before gradually involuting (or shrinking) on its own, usually within the first 5 years of life. Capillary hemangiomas can be superficial, appearing as a bright red, raised lesion on the skin, or deep, forming a bluish, compressible mass beneath the skin.
2. Cavernous hemangioma: This type is less common and typically appears during infancy or early childhood. It consists of large, dilated blood vessels and can occur in various organs, including the skin, liver, brain, and gastrointestinal tract. Cavernous hemangiomas on the skin appear as a rubbery, bluish mass that does not typically involute like capillary hemangiomas.
Most hemangiomas do not require treatment, especially if they are small and not causing any significant problems. However, in cases where hemangiomas interfere with vital functions, impair vision or hearing, or become infected, various treatments may be considered, such as medication (e.g., corticosteroids, propranolol), laser therapy, surgical excision, or embolization.
Benign fibrous histiocytoma (BFH) is a common benign tumor of the skin and superficial soft tissues. It primarily affects middle-aged adults and is more prevalent in men than women. The exact cause of BFH is unknown, but it's thought to arise from dermal fibroblasts or histiocytes.
Medical Definition: Benign Fibrous Histiocytoma (BFH) is a benign, slowly growing, solitary cutaneous or subcutaneous nodular tumor predominantly composed of a mixture of fibroblastic and histiocytic-like cells. The tumor typically presents as a well-circumscribed, firm, dome-shaped papule or nodule, ranging in size from a few millimeters to several centimeters. Histologically, BFH is characterized by the proliferation of spindle-shaped fibroblasts and histiocytes arranged in a storiform pattern, along with variable amounts of collagen deposition, multinucleated giant cells, and hemosiderin deposits. The lesion usually has a pushing border with no invasion into the surrounding tissues. BFH generally follows a benign clinical course, with local recurrence being uncommon following complete surgical excision.
Averill A. Liebow
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International Classification of Diseases for Oncology
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Neoplasm
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p53 protein expression and genetic mutation in two primary cell types in pulmonary sclerosing haemangioma | Journal of Clinical...
Solitary Pulmonary Nodule: Background, Types of Benign Pulmonary Tumors, Etiology of Solitary Pulmonary Nodule
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Chronic obstruc1
- The Underdiagnosis of Chronic Obstructive Pulmonary Disease in Women. (archbronconeumol.org)
Nodules10
- a Critical Images slideshow, for more information on benign and malignant etiologies of solitary pulmonary nodules. (medscape.com)
- Patients with solitary pulmonary nodules are usually asymptomatic. (medscape.com)
- However, solitary pulmonary nodules can pose a challenge to clinicians and patients. (medscape.com)
- Most solitary pulmonary nodules are benign. (medscape.com)
- BACKGROUND: The ability of lung cancer screening to manage pulmonary nodules was limited because of the high false-positive rate in the current mainstream screening method, low-dose computed tomography (LDCT). (bvsalud.org)
- Of 79,581 who received LDCT screening, 5165 participants with suspected pulmonary nodules were allocated into the training set, of which, 149 lung cancer cases were diagnosed. (bvsalud.org)
- Multiple Pulmonary Nodules" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
- This graph shows the total number of publications written about "Multiple Pulmonary Nodules" by people in this website by year, and whether "Multiple Pulmonary Nodules" was a major or minor topic of these publications. (wakehealth.edu)
- Below are the most recent publications written about "Multiple Pulmonary Nodules" by people in Profiles. (wakehealth.edu)
- Computed tomography (CT), performed in June 20XX, showed newly emerging lesions, such as multiple nodules in both lungs, a right axillary tumor, and the already-known hepatic lesion (multiple enlarged hepatic hemangiomas). (springeropen.com)
Solitary pulmon2
- A solitary pulmonary nodule is defined as a discrete, well-marginated, rounded opacity less than or equal to 3 cm in diameter that is completely surrounded by lung parenchyma, does not touch the hilum or mediastinum, and is not associated with adenopathy, atelectasis , or pleural effusion . (medscape.com)
- [ 1 ] Therefore, prompt diagnosis and management of early lung cancer manifesting as a solitary pulmonary nodule is the the best chance for cure. (medscape.com)
Hepatic hemangiomas3
- A 61-year-old man was under observation for multiple hepatic hemangiomas. (springeropen.com)
- Contrast-enhanced computed tomography showed a right axillary tumor and enlarged hepatic hemangiomas. (springeropen.com)
- Benign neoplasm of liver include hepatic hemangiomas, hepatic adenomas , and focal nodular hyperplasia (FNH). (wikidoc.org)
Tumors include1
- Examples of vascular tumors include infantile hemangioma, kaposiform hemangioendothelioma (KH), and tufted angioma (TA). (e-acfs.org)
Hypertension1
- Experimental pulmonary arterial hypertension (aorta to pulmonary artery shunt) and effects of hyperkinesis (total pulmonary flow diverted to one lung) were shown to be reliable models for human pulmonary hypertension. (wikipedia.org)
Lung Tumors1
- Benign lung tumors are a heterogenous group of neoplastic lesions originating from pulmonary structures. (medscape.com)
Vascular lesions2
- Solitary hemangiomas are the most common vascular lesions of bone. (basicmedicalkey.com)
- This department provides medical care for patients with bronchial, lung and pleural tumors, respiratory tract infections, pulmonary vascular lesions, and respiratory failure. (japanhospitalsearch.org)
Lesions1
- The patient visited our hospital for the first time in 2019, and brain computed tomography revealed several enhanced lesions with venous engorgement and phlebolith formation involving the left face, left masticator space, and left orbital cavity, complicated with multiple hemangiomas. (jmedscindmc.com)
Embolism1
- It's worth noting that people with large varicose veins are more likely to suffer from other conditions like a pulmonary embolism. (southlakeobgyn.net)
Bronchial1
- He described important aspects of vascular pathology in pulmonary emphysema, notably the expansion of the bronchial venous collateral circulation. (wikipedia.org)
Venous1
- A congenital disorder that is characterized by a triad of capillary malformations (HEMANGIOMA), venous malformations (ARTERIOVENOUS FISTULA), and soft tissue or bony hypertrophy of the limb. (lookformedical.com)
Artery1
- The pulmonary artery flotation catheter is debatable because the prognosis for children older than age years. (elastizell.com)
Renal2
- Renal and pulmonary function needs to be monitored with intervention as needed. (arizona.edu)
- 1 month) resulting in rapid hepatic compensation characterized by synthetic dysfunction ( hypoglycemia , coagulopathy ), coma ( cerebral edema , hepatic encephalopathy ) and associated with infectious, renal, pulmonary and metabolic complications. (wikidoc.org)
Nodule2
- Right upper lobe nodule shows peripheral calcification and high Hounsfield unit enhancement, suggesting that the lesion is a calcified, benign pulmonary nodule. (medscape.com)
- Generally, a pulmonary nodule must reach 1 cm in diameter before it can be identified on a chest radiograph. (medscape.com)
Neoplasms1
- They are differentiated from neoplasms of vascular tissue (NEOPLASMS, VASCULAR TISSUE), such as ANGIOFIBROMA or HEMANGIOMA. (lookformedical.com)
Veins1
- The Vasculaze device emits optical energy power that can address spider veins as well as other skin problems like port wine stains, angiomas, and hemangiomas. (southlakeobgyn.net)
Including papillary1
- Sclerosing hemangiomas show a combination of many different architectural patterns, including papillary (depicted here), solid, angiomatoid/hemorrhagic, and sclerotic. (webpathology.com)
Malignant1
- Malignant vascular tumors of bone occur less frequently than hemangiomas. (basicmedicalkey.com)
Syndrome1
- Dissolution of bone caused by either lymphangiomas or hemangiomas is termed Gorham-Stout syndrome. (medscape.com)
Cancer1
- Herein we describe a patient with axillary EHE as a comorbidity of papillary thyroid cancer (PTC) and hepatic hemangioma. (springeropen.com)
Primary1
- Dr. Francis P. Mc Carthy , Boston: The terminology of sclerosing angioma suggests a primary hemangioma that undergoes sclerosis. (jamanetwork.com)
Treatment2
- The toxic effects of the treatment were associated with the injection volume and may be related to ethanol-induced pulmonary vasoconstriction and transient right ventricular dysfunction. (jmedscindmc.com)
- Prompt and proper management, including providing supportive treatment, decreasing pulmonary vascular resistance with pulmonary vasodilators, and improving right ventricular function, should be carefully prepared to minimize the progression of cardiovascular collapse. (jmedscindmc.com)
Function1
- Fellows will also learn to be proficient in skills important for Allergy/Immunology practice and the American Board of Allergy and Immunology including epicutaneous and intradermal skin testing, pulmonary function testing, allergy immunotherapy preparation and administration, food and drug desensitization and immunoglobulin replacement. (childrensdmc.org)
Agent2
- Ethanol is a safe and effective sclerosing agent. (jmedscindmc.com)
- This method involves injecting a sclerosing agent into the affected vein. (southlakeobgyn.net)
Multiple1
- A 61-year-old man had been referred to the Department of Hepatobiliary and Pancreatic Surgery of our hospital for multiple hepatic giant hemangiomas with no significant progression, 5 years before his first visit to our department. (springeropen.com)
Method1
- Percutaneous intralesional injection of liquid sclerosing agents, also known as sclerotherapy, is a therapeutic method commonly applied to address low-flow vascular malformations. (jmedscindmc.com)