SUNCT Syndrome
Headache
Chronic paroxysmal hemicrania, hemicrania continua and SUNCT: the fate of the three first described cases. (1/20)
The first patient with chronic paroxysmal hemicrania has been followed for 45 years, and for 33 years with indomethacin treatment. The headache became less severe with time; there was no indomethacin tachyphylaxis. The first patient with SUNCT was followed for 28 years, until his demise at 89. Pain became worse with time. No adequate therapy was found. The first patient with Hemicrania continua was followed for 19 years, until her demise at 81. She was treated with indomethacin during the whole observation time. There was no tachyphylaxis. Both patients treated with indomethacin developed gastric ulcer. And both had gastric surgery. Indomethacin therapy may be a life-long affair. The risk of gastric complications may be substantial. (+info)Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) or cranial autonomic features (SUNA)--a prospective clinical study of SUNCT and SUNA. (2/20)
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic features (SUNA) are described, although SUNA is rarely reported. The phenotype of SUNCT and SUNA was characterized from a large series of patients (43 SUNCT, 9 SUNA). Three attack types were identified: stabs, groups of stabs and saw-tooth attacks. The mean duration of stabs was 58 s (1-600 s); stab groups, 396 s (10-1200 s); and saw-tooth, 1160 s (5-12 000s). The attack frequency was a mean of 59 attacks/day (2-600), and this depended largely on the type of attack. The pain was orbital, supraorbital or temporal in 38 (88%) SUNCT and 7 (78%) SUNA, and also occurred in the retro-orbital region, side, top, back of head, second and third trigeminal divisions, teeth, neck and ear. All SUNCT patients had conjunctival injection and tearing. Two SUNA patients had conjunctival injection, four had tearing, but none had both. Other cranial autonomic symptoms included nasal blockage, rhinorrhoea, eyelid oedema, facial sweating/flushing and ear flushing. Cutaneous stimuli triggered attacks in 74% of SUNCT but only in 22% of SUNA patients. The majority (95% SUNCT and 89% SUNA) had no refractory period between attacks. For SUNCT 58% and for SUNA 56% of patients were agitated with the attacks. We propose a new set of diagnostic criteria for these syndromes to better encompass the clinical presentations and which include a wider range of attack length, wider trigeminal pain distribution, cutaneous triggering and lack of refractory period. (+info)Bilateral SUNCT syndrome associated to chronic maxillary sinus disease. (3/20)
SUNCT syndrome (short lasting unilateral neuralgiform headache with conjunctival injection and tearing) is defined as short attacks of periorbital unilateral pain and accompanied by ipsilateral lacrimation and redness of the same eye. We present an unusual SUNCT case with bilateral pain that started five years ago after an acute maxillary sinus infection that evolved to chronic sinusitis. This association has been described in few SUNCT cases, but its causal role remains uncertain. The patient was a 58 year old man that fulfilled a headache diary that showed the usual circadian pattern, worsening in the morning and afternoon, and responded to treatment with gabapentine. He was submitted to a functional endoscopic sinus surgery and evolved with milder pain. In a review of 21 patients, 5 had a past medical history of sinusitis, but the causal role of this association remained uncertain. (+info)SUNCT syndrome associated with pituitary tumor: case report. (4/20)
For twelve years, the subject of this report, a 38-year-old man, presented a clinical condition compatible with the SUNCT (short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing) syndrome. He presented a stabbing and intense daily pain located in the left pre-auricular and temporal regions. Each of these intense pain attacks lasted around one minute and presented a frequency of two to eight times per day. The pain was associated with ipsilateral lacrimation, conjunctival injection and rhinorrhea. MRI revealed a pituitary tumor with little suprasellar extent. The subjects serial assays of prolactin, GH, TSH and ACTH were within normal levels. Following transsphenoidal hypophysectomy, with complete removal of the tumor, the subject no more presented pain. The pathological diagnosis was non-secreting adenoma. Fourteen months after the surgery, he remains symptom-free. (+info)Black, white and shades of grey: SUNCT or short-lasting chronic paroxysmal hemicrania? (5/20)
AIM OF THE STUDY: To report a case of unilateral headache with two possibilities of diagnosis. METHOD: Case report. RESULTS: Patient with unilateral, intense, stabbing periocular headache with conjuntival injection and tearing. Although the duration of attacks was typical of SUNCT, there was complete remission of the pain with indomethacin, suggesting that this was a case of chronic paroxysmal hemicrania with unusually short attack duration. CONCLUSION: Therapeutic trials of indomethacin on younger patients presenting clinical diagnosis of SUNCT could be tried on a more regular basis. (+info)SUNCT and high nocturnal prolactin levels: some new unusual characteristics. (6/20)
SUNCT is a rare condition characterised by a short-lasting periorbital pain associated with autonomic symptoms and is usually unresponsive to pharmacological treatment. We report a case of SUNCT syndrome linked to a pituitary micro-adenoma, with only nocturnal attacks. The nocturnal levels of prolactin (PRL) were increased, while other hormonal, haematological, serological and biochemical investigations and levels of PRL did not reveal abnormal findings during the day-time. PRL serum secretion after thyrotropin-releasing hormone test was lower than nocturnal secretion, but not enough to induce severe attacks. We suggest that in our patient the rise of nocturnal levels of PRL could have a direct role in the worsening of this headache, perhaps secondarily to an altered regulation of the hypothalamic-hypophysial axis, however the actual influence of sleep and the interaction between all neurotransmitters and hormones needs to be clarified further. (+info)SUNCT syndrome: report of a possible symptomatic case. (7/20)
SUNCT is one of the rarest and least known primary headache disorders. Although its pathogenesis has been partially understood by functional neuroimaging and reports of secondary cases, there is limited understanding of its cause. We report a case of SUNCT in a 54-years-old man, that could not be strictly classified as secondary SUNCT; however, the time lag of pain onset suggests a new theory in which neuroplasticity could be involved in the origin and duration of the pain in SUNCT syndrome. (+info)SUNCT and trigeminal neuralgia attributed to meningoencephalitis. (8/20)
(+info)SUNCT syndrome, an acronym for Short-lasting Unilateral Neuralgiform headache attacks with Conjunctival injection and Tearing, is a rare and severe type of headache disorder. It is characterized by recurrent episodes of intense, one-sided (unilateral) head pain that typically lasts for a short duration (less than 5 minutes). The headaches are often described as stabbing or piercing and can be triggered by various stimuli such as touch, movement, or temperature changes.
In addition to the head pain, SUNCT syndrome is also associated with autonomic symptoms, including redness (conjunctival injection) and tearing of the eye on the same side as the headache. Other possible autonomic symptoms include sweating, nasal congestion, and pupil changes.
SUNCT syndrome can be challenging to diagnose and treat due to its rarity and severity. It is typically managed with a combination of medications, including anti-epileptic drugs, and in some cases, invasive procedures such as nerve blocks or neurostimulation may be considered.
A headache is defined as pain or discomfort in the head, scalp, or neck. It can be a symptom of various underlying conditions such as stress, sinus congestion, migraine, or more serious issues like meningitis or concussion. Headaches can vary in intensity, ranging from mild to severe, and may be accompanied by other symptoms such as nausea, vomiting, or sensitivity to light and sound. There are over 150 different types of headaches, including tension headaches, cluster headaches, and sinus headaches, each with their own specific characteristics and causes.
A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.
For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.
It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.
SUNCT syndrome
H.R.
Cluster headache
List of MeSH codes (C10)
International Classification of Headache Disorders
Pituitary adenoma
SON (gene)
SUNCT syndrome - Wikipedia
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SUNA12
- Short-lasting unilateral neuralgiform headache attacks with cranial autonomic features (SUNA) is a subset of SUNCT that constitutes less than 20% of all reported cases, and may be diagnosed when fewer autonomic symptoms are observed during attacks. (wikipedia.org)
- The main difference between SUNCT and SUNA is the clinical presentation of the secondary autonomic symptoms. (wikipedia.org)
- Like SUNCT, SUNA is a trigeminal autonomic cephalgia (TAC) characterized by attacks of trigeminal pain accompanied by cranial autonomic symptoms other than red eye and tearing. (face-facts.org)
- Short-Lasting Unilateral Neuralgiform Headache With Conjunctival Injection and Tearing (SUNCT) Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attack (SUNA) are rare headache disorders characterized. (msdmanuals.com)
- The other 3 TACs are cluster headache , hemicrania continua , and SUNCT/SUNA . (virtualheadachespecialist.com)
- Intencionalmente se buscaron síntomas autonómicos en éstos y se compararon con los criterios diagnósticos de SUNCT y SUNA de la Clasificación Internacional de las Cefaleas, tercera edición. (bvsalud.org)
- Tras la revisión de las manifestaciones clínicas, se encontró a 12 pacientes con síntomas autonómicos y se compararon con los criterios diagnósticos de SUNCT y SUNA. (bvsalud.org)
- Conclusión: La NT es una entidad dolorosa y frecuente que puede presentar síntomas autonómicos, y es importante pensar en diagnósticos diferenciales, como la SUNCT y la SUNA, para la identificación y el tratamiento correctos. (bvsalud.org)
- Autonomic symptoms were intentionally searched for in these patients and compared with the diagnostic criteria of SUNCT and SUNA of the 3rd edition of the International Classification of Headache Disorders. (bvsalud.org)
- After reviewing the clinical manifestations, 12 patients with autonomic symptoms were found and compared with the diagnostic criteria of SUNCT and SUNA. (bvsalud.org)
- Conclusions: TN is a painful and frequent entity that can present with autonomic symptoms, therefore making it important to identify SUNCT and SUNA as differential diagnoses, to recognize them and treat them appropriately. (bvsalud.org)
- Cluster headaches, paroxysmal hemicranias, short-lasting unilateral neuralgiform headache attacks (SUNCT and SUNA), and hemicrania continua are all examples of the Trigeminal Autonomic Cephalalgias (TAC), a class of primary headache diseases. (com.bd)
Hemicrania continua1
- Primary headaches are conditions where the headache is the medical problem - Migraine, Cluster headache, Tension headaches, SUNCT, hemicrania continua etc are examples. (macsclinic.co.uk)
Autonomic symptoms1
- SUNCT often accompanies cranial autonomic symptoms, including lacrimation (tear flow), ipsilateral ptosis (drooping of the eyelid which is on the same side as the attacks), eyelid edema (swelling due to fluid accumulation), nasal blockage, and conjunctival injection (redness of eye). (wikipedia.org)
Headache syndromes2
- Red ear syndrome is an uncommon primary pain disorder thought to be a variant of one of a group of three headache syndromes known as the trigeminal autonomic cephalgias. (seekhealthz.com)
- Neurostimulation in primary headache syndromes. (watsonheadache.com)
Conjunctival injection9
- Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT syndrome) is a rare headache disorder that belongs to the group of headaches called trigeminal autonomic cephalalgia (TACs). (wikipedia.org)
- In SUNCT, both conjunctival injection (red eyes) and lacrimation on the same side of the headache should be present. (wikipedia.org)
- The SUNCT syndrome (short-unilateral neuralgiform headache with conjunctival injection and tearing) can be very disabling for affected patients and is often refractory to medical management. (world-sci.com)
- SUNCT stands for short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing. (migraineprofessional.com)
- Short lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is a trigeminal autonomic cephalgia (TAC) characterized by attacks of trigeminal pain accompanied by red eye (conjunctival injection) and tearing (lacrimation. (face-facts.org)
- Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing syndrome: a review.Curr Pain Headache Rep. 2003 Aug;7(4):308-18. (face-facts.org)
- This redness involves the entire ear, including the pinna, and is associated with neuralgia-like pain reminiscent of sudden unilateral neuralgiform conjunctival injection tearing (SUNCT) headache. (seekhealthz.com)
- The Autonomic cephalgias frequently respond well to Sphenopalatine Ganglion Blocks Attacks occurring at regular intervals in a predictable patterns or including eye redness and tearing and include cluster headache, short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT), short lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA), or trigeminal neuralgia. (thinkbetterlife.com)
- Objective: Identify the number of cases with a possible diagnosis of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) or short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) in patients with a previous diagnosis of Trigeminal Neuralgia (TN) at the Neurology Service of the National Medical Center 20 de Noviembre. (bvsalud.org)
Facial pain syndromes4
- Medical treatment of PIFP is usually less satisfactory than medical treatment of other facial pain syndromes. (medscape.com)
- Within the group of chronic facial pain syndromes, PIFP represents a particular diagnostic challenge. (medscape.com)
- Treatment of PIFP is typically less effective than that of other facial pain syndromes, and a multidisciplinary approach is required to address the many facets of this pain syndrome. (medscape.com)
- However, because of the overlapping features of all headache and facial pain syndromes, red ear syndrome easily can be mistaken for another type of headache or facial pain. (seekhealthz.com)
Medically-refractory2
- Gamma knife radiosurgery is an option for medically-refractory SUNCT patients. (world-sci.com)
- BACKGROUND: Microvascular decompression (MVD) is already the preferred surgical treatment for medically refractory neurovascular compression syndromes (NVC) such as hemifacial spasm (HFS), trigeminal neuralgia (TN), and glossopharyngeal neuralgia (GPN). (bvsalud.org)
Headaches6
- SUNCT must be properly distinguished from cluster headaches, since cluster headaches also occur several times per day with separate attacks, and share some common symptoms. (wikipedia.org)
- In this article, we will be talking about 5 Incredible tools for the SUNCT headaches syndrome. (migraineprofessional.com)
- There are many different triggers for SUNCT headaches and some of them the same as cluster headaches and migraines like certain lights, scents, and smoke. (migraineprofessional.com)
- In late January, we revealed that Bad Brains frontman H.R. was awaiting brain surgery on Feb. 21 to thwart a rare neurological condition, SUNCT, that resulted in headaches 'so great that he yells, cries out, groans, and sobs-repeatedly, every few minutes, for most of the night. (loudwire.com)
- This headache disorder is different from other headaches that cause stabbing pain due to its irregular occurrence and lack of redness or tearing of the eyes commonly found with SUNCT. (thinkbetterlife.com)
- such headaches are a concern because they may be caused by a cerebrospinal fluid (CSF) leak or postural orthostatic tachycardia syndrome (POTS). (msdmanuals.com)
Refractory2
- In chronic SUNCT, attacks can occur regularly or irregularly without a distinct refractory period, whereas in episodic SUNCT, attacks occur only for a certain period of time and then cease for another period. (wikipedia.org)
- where to buy clomid in uk Chronic short-lasting unilateral neuralgiform headache attacks SUNCT off-label use if SUNCT refractory to other recommended medications Initial recommended dosing is 50mg orally daily. (fotoschelfhout.be)
Paroxysmal hemicrania1
- The pain of chronic paroxysmal hemicrania lasts much longer than the pain of red ear syndrome. (seekhealthz.com)
Unilateral3
- As its name implies, the pathognomonic finding of red ear syndrome is in fact a unilateral red ear. (seekhealthz.com)
- Although in many ways similar to SUNCT headache (i.e., unilateral, rapid onset to peak, short duration of attacks, pain-free periods between attacks), many dissimilarities also exist, including the location and pronounced autonomic phenomenon manifested by the red ear. (seekhealthz.com)
- Patients with red ear syndrome present with the complaint of severe paroxysms of sudden onset of unilateral ear redness associated with pain involving the ipsilateral ear. (seekhealthz.com)
Symptoms2
- In some cases, patients with episodic SUNCT only exhibit symptoms biannually, in spring and fall. (wikipedia.org)
- Whether red ear syndrome is in fact a distinct pain syndrome resulting from auriculo-autonomic dysfunction or simply a constellation of symptoms that occurs on a continuum along with the other trigeminal autonomic cephalgias is a point of ongoing debate among headache and pain management specialists. (seekhealthz.com)
Occipital1
- Porta-Etessam J, Cuadrado ML, Galán L, Sampedro A, Valencia C. Temporal response to bupivacaine bilateral great occipital block in a patient with SUNCT syndrome. (watsonheadache.com)
Chronic1
- SUNCT can go into remission even after a chronic period, and relapse either spontaneously or due to some stimulus. (wikipedia.org)
Suicide syndrome2
- This pain is described as being the most intense pain known to man, and is often referred to as 'suicide syndrome. (loudwire.com)
- H.R. has been suffering from serious health issues lately, namely a cluster headache disorder called SUNCT or "Suicide Syndrome. (965therock.com)
Clinical1
- Red ear syndrome is a clinical diagnosis supported by a combination of clinical history, normal physical examination, radiography, and MRI. (seekhealthz.com)
Diagnosis4
- Pareja JA1, Caminero AB, Sjaastad O. SUNCT Syndrome: diagnosis and treatment. (face-facts.org)
- Screening laboratory tests consisting of complete blood cell count, erythrocyte sedimentation rate, and automated blood chemistry should be performed if the diagnosis of red ear syndrome is in question. (seekhealthz.com)
- Diagnosis and Management of Opsoclonus-Myoclonus-Ataxia Syndrome in Children: An International Perspective. (nih.gov)
- Congenital central hypoventilation syndrome: diagnosis and management. (nih.gov)
Disorder1
- The treatment of red ear syndrome is analogous to the treatment of trigeminal neuralgia, although the pharmacological management of this uncommon headache disorder is disappointing. (seekhealthz.com)
Attacks3
- The headache attacks are typically accompanied by cranial autonomic signs that are unique to SUNCT. (wikipedia.org)
- People affected by SUNCT often describe their headache attacks as excruciating pain. (wikipedia.org)
- The pain and erythema associated with red ear syndrome have a rapid onset to peak, with attacks lasting 15 seconds to 5 minutes and the frequency of attacks ranging from 20 to 200 attacks per day. (seekhealthz.com)
Occurs2
- Red ear syndrome occurs slightly more frequently in males. (seekhealthz.com)
- Digital eyestrain , also called computer eyestrain or computer vision syndrome, is a type of eyestrain that occurs in people who use digital electronic devices, such as computers and tablets, for prolonged periods. (medicalnewstoday.com)
Uncommon1
- Although the majority of patients are men over the age of 50, it is not uncommon to find SUNCT present among other age groups, including children and infants. (wikipedia.org)
Trigeminal neuralgia1
- Like trigeminal neuralgia, the pain of red ear syndrome rarely switches sides. (seekhealthz.com)
Surgery1
- The crowdfunding campaign also details the severity of the SUNCT condition, explaining, 'The surgery is most often performed on people who suffer from trigeminal neuralgi a, which causes pain in the cheek. (loudwire.com)
Pain2
- This syndrome can attack up to 200 times per day with pain frequently reported as a 9 out of 10. (migraineprofessional.com)
- Challenging pain syndromes: Parsonage-Turner syndrome. (nih.gov)
Predominant1
- The syndrome is predominant in males, with a mean age of onset around 50 years. (face-facts.org)
Patients1
- Stimuli capable of triggering a cluster headache, including alcohol, smoke, strong smells and a warm environment, can also trigger SUNCT in a few patients. (wikipedia.org)
Treatment1
- After failing optimal medical treatment, a 82-year old male patient suffering from right-sided SUNCT syndrome was treated with Gamma knife radiosurgery. (world-sci.com)