A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.
A species of mite that causes SCABIES in humans and sarcoptic mange in other animals. Specific variants of S. scabiei exist for humans and animals, but many have the ability to cross species and cause disease.
A pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
Drugs used to treat or prevent parasitic infections.
Parasitic attack or subsistence on the skin by members of the order Phthiraptera, especially on humans by Pediculus humanus of the family Pediculidae. The hair of the head, eyelashes, and pubis is a frequent site of infestation. (From Dorland, 28th ed; Stedman, 26th ed)
A pesticide or chemical agent that kills mites and ticks. This is a large class that includes carbamates, formamides, organochlorines, organophosphates, etc, that act as antibiotics or growth regulators.
An organochlorine insecticide that has been used as a pediculicide and a scabicide. It has been shown to cause cancer.
Territory in north central Australia, between the states of Queensland and Western Australia. Its capital is Darwin.
Any purulent skin disease (Dorland, 27th ed).
A pyridoxal-phosphate protein that catalyzes the conversion of L-tyrosine to tyramine and carbon dioxide. The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine. (From Enzyme Nomenclature, 1992) EC 4.1.1.25.

Gonorrhoea in patients with scabies. (1/134)

242 patients with scabies were examined for gonorrhoea at the Municipal Hospital of Copenhagen over a one-year period. We found asymptomatic gonorrhoea in 2% of the male patients and 12%. of the female patients. The incidence of gonorrhoea in female patients with scabies is thus higher than in other routinely examined groups of patients (Andersen and Nielsen, 1974; Gregersen, 1972; Hansen and Lange, 1973; Nielsen, 1974; Starck, Bygdeman, Eriksson, Heinerz, and Moberg, )971). Our suggestion is that all patients with scabies, male as well as female, should be examined routinely for gonorrhoea.  (+info)

The epidemiology of head lice and scabies in the UK. (2/134)

Anecdotal evidence suggests that the prevalence of both scabies and head lice is increasing and also that both conditions are becoming refractory to pesticide treatment. Using information obtained from the Office of National Statistics, Royal College of General Practitioners Weekly Returns Service, Department of Health, local surveys of school children from Bristol and drug sales of insecticides, we have confirmed that there has been a rise in the prevalence of both conditions. We have shown that scabies is significantly more prevalent in urbanized areas (P < 0.00001), north of the country (P < 0.000001), in children and women (P < 0.000001) and commoner in the winter compared to the summer. Scabies was also shown to have a cyclical rise in incidence roughly every 20 years. Head lice were shown to be significantly more prevalent in children and mothers (P < 0.000001) though both conditions were seen in all age groups. Head lice were also less common during the summer. Host behaviour patterns, asymptomatic carriage, drug resistance and tourism from countries or districts with a higher incidence may be important factors in the currently high prevalence of both scabies and head lice.  (+info)

Crusted scabies: A molecular analysis of Sarcoptes scabiei variety hominis populations from patients with repeated infestations. (3/134)

Crusted scabies is a severe debilitating disease due to hyperinfestation with the ectoparasite Sarcoptes scabiei. Treatment protocols include oral ivermectin and topical scabicides. After single-dose ivermectin, there may be early recrudescence, whereas after 3 doses at 14-day intervals, there is an apparent cure. However, such patients often present again after 6-12 months. To clarify the biology of recurrence, we studied genetic markers in sequential populations of S. scabiei mites from treated patients with multiple episodes of crusted scabies. Individual mites were genotyped at hypervariable microsatellite loci by a fluorescence-based polymerase chain reaction. Results indicated that sequential populations of mites were genetically more similar to each other than to mites from other patients. Although the majority of recurrent scabies is probably due to reinfestation from inadequately treated contacts, there was evidence that in very severe crusted scabies, treatment with even 3 doses of ivermectin 14 days apart may be inadequate and relapse may occur.  (+info)

Genetically distinct dog-derived and human-derived Sarcoptes scabiei in scabies-endemic communities in northern Australia. (4/134)

Overcrowding is a significant factor contributing to endemic infection with Sarcoptes scabiei in human and animal populations. However, since scabies mites from different host species are indistinguishable morphologically, it is unclear whether people can be infected from scabies-infested animals. Molecular fingerprinting was done using three S. scabiei-specific single locus hypervariable microsatellite markers, with a combined total of 70 known alleles. Multilocus analysis of 712 scabies mites from human and dog hosts in Ohio, Panama and Aboriginal communities in northern Australia now shows that genotypes of dog-derived and human-derived scabies cluster by host species rather than by geographic location. Because of the apparent genetic separation between human scabies and dog scabies, control programs for human scabies in endemic areas do not require resources directed against zoonotic infection from dogs.  (+info)

Treatment of human scabies with oral ivermectin. (5/134)

Thirty-eight patients with scabies (21 males and 17 females) received oral ivermectin in two doses of 200 microg/kg at 7 days interval. Excellent results were achieved in 29 cases (76.34%), improvement in 6 (15.78%) and poor responses in 3 (7.88%). Tolerance was satisfactory-excellent in 32 patients (84.2%). The effectiveness and safety of the drug described in previous studies are confirmed by the present results.  (+info)

Invading parasites cause a structural shift in red fox dynamics. (6/134)

The influence of parasites on host life histories and populations is pronounced. Among several diseases affecting animal populations throughout the world, sarcoptic mange has influenced many carnivore populations dramatically and during the latest epizootic in Fennoscandia reduced the abundance of red fox by over 70%. While the numerical responses of red fox populations, their prey and their competitors as well as clinical implications are well known, knowledge of how sarcoptic mange affects the structure of the dynamics of red fox populations is lacking. Integrating ecological theory and statistical modelling, we analysed the long-term dynamics (1955-1996) of 14 Danish red fox populations. As suggested by the model, invading sarcoptic mange significantly affected direct and delayed density dependence in red fox dynamics and concomitant shifts in fluctuation patterns were observed. Our statistical analyses also revealed that the spatial progressive spread of mange mites was mirrored in the autocovariate structures of red fox populations progressively exposed to sarcoptic mange.  (+info)

Crusted (Norwegian) scabies in two old-age home residents. (7/134)

Scabies is commonly seen in hospitals, where it frequently affects geriatric and convalescent patients. The clinical features of the classic form of scabies are well recognised. Crusted (Norwegian) scabies, which is a hyperinfestation variant of scabies, is very contagious and can present as other dermatoses, thus delaying the correct diagnosis and management. Two residents of different old-age homes presented with hyperkeratotic skin eruptions, which later proved to be crusted scabies. In both cases, the scabies was initially misdiagnosed as eczema. The delay in making a correct diagnosis led to an outbreak of scabies in the old-age home in which one of the patients was residing.  (+info)

Gonorrhoea in 1972. A 1-year study of patients attending the VD Unit in Uppsala. (8/134)

During 1972 a total of 2,090 men and 1,489 women were seen in the VD clinic in Uppsala, Sweden. The most frequent diagnosis among the men was non-gonococcal urethritis (38 per cent.) and among the women non-gonococcal vaginitis (34 per cent.), N. gonorrhoeae was found in 22 per cent. of the men and in 33 per cent. of the women, 68 per cent. of the men with gonorrhoea attended because of symptoms, but 67 per cent. of the men without gonococcal infections came for the same reason. 39 per cent. of the women with gonorrhoea attended after being told by their sexual partner; it was found that women coming because of symptoms were most likely to have non-gonococcal infection. Gonorrhoea without subjective symptoms was found in 23 per cent. of the men and 50 per cent. of the women. Gonorrhoea was found in association with scabies in 9 out of 18 men and in 3 out of 5 women. A rising incidence of pharyngeal gonococcal infections has been noticed at the clinic and the figures for 1972 were 6 per cent. of the men and 9 per cnet. of the women with gonorrhoea. The route of infection was usually oro-genital contact, but in some cases other routes had to be considered. It was not possible to define a promiscuous group of patients suitable for a planned study of prophylactic treatment, as only 2 per cent. of the men and 1 per cent. of the women had had nore than one gonococcal infection during the preceding year. The standard treatment for genital gonorrhoea (ampicillin 2 times 1 g. orally with a 5-hour interval) was very satisfactory and gave a 98 per cent. cure rate. This was possible because there were few gonococcal strains with decreased panicillin sensitivity. There were considerable problems in treating the pharyngeal infections, the standard treatment failing in 61 per cent.  (+info)

Scabies is a contagious skin condition caused by the infestation of the human itch mite (Sarcoptes scabiei var. hominis). The female mite burrows into the upper layer of the skin, where it lays its eggs and causes an intensely pruritic (itchy) rash. The rash is often accompanied by small red bumps and blisters, typically found in areas such as the hands, wrists, elbows, armpits, waistline, genitals, and buttocks. Scabies is transmitted through direct skin-to-skin contact with an infected individual or through sharing of contaminated items like bedding or clothing. It can affect people of all ages, races, and socioeconomic backgrounds, but it is particularly common in crowded living conditions, nursing homes, and child care facilities. Treatment usually involves topical medications or oral drugs that kill the mites and their eggs, as well as thorough cleaning and laundering of bedding, clothing, and towels to prevent reinfestation.

"Sarcoptes scabiei" is a medical term that refers to a species of mite known as the human itch mite or simply scabies mite. This tiny arthropod burrows into the upper layer of human skin, where it lives and lays its eggs, causing an intensely itchy skin condition called scabies. The female mite measures about 0.3-0.5 mm in length and has eight legs. It is barely visible to the naked eye.

The mite's burrowing and feeding activities trigger an immune response in the host, leading to a characteristic rash and intense itching, particularly at night. The rash typically appears as small red bumps or blisters and can occur anywhere on the body, but is most commonly found in skin folds such as the wrists, elbows, armpits, waistline, and buttocks.

Scabies is highly contagious and can spread rapidly through close physical contact with an infected person, shared bedding or towels, or prolonged skin-to-skin contact. It is important to seek medical treatment promptly if scabies is suspected, as the condition can cause significant discomfort and lead to secondary bacterial infections if left untreated. Treatment typically involves topical medications that kill the mites and their eggs, as well as thorough cleaning of bedding, clothing, and other items that may have come into contact with the infected person.

Permethrin is a type of medication that belongs to the class of chemicals called pyrethroids. It's commonly used as a topical treatment for scabies and lice infestations. Permethrin works by disrupting the nervous system of these parasites, leading to their paralysis and death.

In medical terms, permethrin is defined as a synthetic pyrethroid insecticide and acaricide with contact and stomach activity. It's used topically in the form of creams or lotions to treat infestations of lice and scabies mites on the skin. Permethrin is considered safe and effective for use in adults and children, including infants over two months old.

It's important to note that permethrin should be used as directed by a healthcare professional, and it may have some potential side effects such as skin irritation, redness, or itching.

Ivermectin is an anti-parasitic drug that is used to treat a variety of infections caused by parasites such as roundworms, threadworms, and lice. It works by paralyzing and killing the parasites, thereby eliminating the infection. Ivermectin is available in various forms, including tablets, creams, and solutions for topical use, as well as injections for veterinary use.

Ivermectin has been shown to be effective against a wide range of parasitic infections, including onchocerciasis (river blindness), strongyloidiasis, scabies, and lice infestations. It is also being studied as a potential treatment for other conditions, such as COVID-19, although its effectiveness for this use has not been proven.

Ivermectin is generally considered safe when used as directed, but it can cause side effects in some people, including skin rashes, nausea, and diarrhea. It should be used with caution in pregnant women and people with certain medical conditions, such as liver or kidney disease.

Antiparasitic agents are a type of medication used to treat parasitic infections. These agents include a wide range of drugs that work to destroy, inhibit the growth of, or otherwise eliminate parasites from the body. Parasites are organisms that live on or inside a host and derive nutrients at the host's expense.

Antiparasitic agents can be divided into several categories based on the type of parasite they target. Some examples include:

* Antimalarial agents: These drugs are used to treat and prevent malaria, which is caused by a parasite that is transmitted through the bites of infected mosquitoes.
* Antiprotozoal agents: These drugs are used to treat infections caused by protozoa, which are single-celled organisms that can cause diseases such as giardiasis, amoebic dysentery, and sleeping sickness.
* Antihelminthic agents: These drugs are used to treat infections caused by helminths, which are parasitic worms that can infect various organs of the body, including the intestines, lungs, and skin. Examples include roundworms, tapeworms, and flukes.

Antiparasitic agents work in different ways to target parasites. Some disrupt the parasite's metabolism or interfere with its ability to reproduce. Others damage the parasite's membrane or exoskeleton, leading to its death. The specific mechanism of action depends on the type of antiparasitic agent and the parasite it is targeting.

It is important to note that while antiparasitic agents can be effective in treating parasitic infections, they can also have side effects and potential risks. Therefore, it is essential to consult with a healthcare provider before starting any antiparasitic medication to ensure safe and appropriate use.

A lice infestation, also known as pediculosis, is a condition characterized by the presence and multiplication of parasitic insects called lice on a person's body. The three main types of lice that can infest humans are:

1. Head lice (Pediculus humanus capitis): These lice primarily live on the scalp, neck, and behind the ears, feeding on human blood. They lay their eggs (nits) on hair shafts close to the scalp. Head lice infestations are most common in children aged 3-12 years old.

2. Body lice (Pediculus humanus corporis): These lice typically live and lay eggs on clothing, particularly seams and collars, near the body's warmest areas. They move to the skin to feed on blood, usually at night. Body lice infestations are more common in people who experience homelessness or overcrowded living conditions with limited access to clean clothing and hygiene facilities.

3. Pubic lice (Pthirus pubis): Also known as crab lice, these lice primarily live in coarse body hair, such as the pubic area, armpits, eyelashes, eyebrows, beard, or mustache. They feed on human blood and lay eggs on hair shafts close to the skin. Pubic lice infestations are typically sexually transmitted but can also occur through close personal contact with an infected individual or sharing contaminated items like bedding or clothing.

Symptoms of a lice infestation may include intense itching, tickling sensations, and visible red bumps or sores on the skin caused by lice bites. In some cases, secondary bacterial infections can occur due to scratching. Diagnosis is usually made through visual identification of lice or nits on the body or clothing. Treatment typically involves topical medications, such as shampoos, creams, or lotions, and thorough cleaning of bedding, clothing, and personal items to prevent reinfestation.

Acaricides are a type of pesticide that are specifically used to kill acarines, which are mites and ticks. These agents work by targeting the nervous system of the acarines, leading to paralysis and eventually death. Acaricides are commonly used in agricultural settings to protect crops from mite infestations, and in medical and veterinary settings to control ticks and mites that can transmit diseases to humans and animals. It is important to use acaricides according to the manufacturer's instructions and to take appropriate safety precautions to minimize exposure to non-target organisms, including humans.

Lindane is defined in medical terms as an agricultural and pharmaceutical compound that contains thegamma-isomer of hexachlorocyclohexane (γ-HCH). It has been used as a topical treatment for scabies and lice infestations, although its use is now limited due to concerns about toxicity and environmental persistence. Lindane works by disrupting the nervous system of insects, leading to paralysis and death. However, it can also have similar effects on mammals, including humans, at high doses or with prolonged exposure. Therefore, its use is restricted and alternatives are recommended for the treatment of scabies and lice.

I'm sorry for any confusion, but "Northern Territory" is not a medical term. It is a geographical and political term referring to a federal territory in Australia. If you have any questions about medical terminology or concepts, I would be happy to help with those!

Pyoderma is a term used in medicine to describe a bacterial skin infection. It's derived from two Greek words: "pyon" meaning pus and "derma" meaning skin.

The infection can result in inflammation, often characterized by redness, swelling, warmth, and pain. Pus-filled blisters or boils may also form, which can rupture and crust over as the infection progresses.

Pyoderma can occur in people of all ages but is particularly common in children. The causative bacteria are often Staphylococcus aureus or Streptococcus pyogenes. The condition can be superficial, affecting only the top layer of the skin (epidermis), or it can be deeper, involving the dermis and/or subcutaneous tissue.

Treatment typically involves antibiotics, either topical or oral, depending on the severity and extent of the infection. In some cases, drainage of pus-filled abscesses may be necessary. Preventive measures such as good hygiene and keeping skin clean and dry can help reduce the risk of pyoderma.

Tyrosine decarboxylase is an enzyme that catalyzes the decarboxylation of the amino acid tyrosine to form the biogenic amine tyramine. The reaction occurs in the absence of molecular oxygen and requires pyridoxal phosphate as a cofactor. Tyrosine decarboxylase is found in various bacteria, fungi, and plants, and it plays a role in the biosynthesis of alkaloids and other natural products. In humans, tyrosine decarboxylase is not normally present, but its activity has been detected in some tumors and is associated with the production of neurotransmitters in neuronal cells.

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