A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.
A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).
Irregular HEART RATE caused by abnormal function of the SINOATRIAL NODE. It is characterized by a greater than 10% change between the maximum and the minimum sinus cycle length or 120 milliseconds.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
The small mass of modified cardiac muscle fibers located at the junction of the superior vena cava (VENA CAVA, SUPERIOR) and right atrium. Contraction impulses probably start in this node, spread over the atrium (HEART ATRIUM) and are then transmitted by the atrioventricular bundle (BUNDLE OF HIS) to the ventricle (HEART VENTRICLE).
A characteristic symptom complex.
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.
The hemodynamic and electrophysiological action of the RIGHT ATRIUM.
A vein which arises from the right ascending lumbar vein or the vena cava, enters the thorax through the aortic orifice in the diaphragm, and terminates in the superior vena cava.
The dilated portion of the common carotid artery at its bifurcation into external and internal carotids. It contains baroreceptors which, when stimulated, cause slowing of the heart, vasodilatation, and a fall in blood pressure.
Transmission of the readings of instruments to a remote location by means of wires, radio waves, or other means. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.
A small nodular mass of specialized muscle fibers located in the interatrial septum near the opening of the coronary sinus. It gives rise to the atrioventricular bundle of the conduction system of the heart.
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
An irregularly shaped venous space in the dura mater at either side of the sphenoid bone.
An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
The chambers of the heart, to which the BLOOD returns from the circulation.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
The air space located in the body of the MAXILLARY BONE near each cheek. Each maxillary sinus communicates with the middle passage (meatus) of the NASAL CAVITY on the same side.
An absence from work permitted because of illness or the number of days per year for which an employer agrees to pay employees who are sick. (Webster's New Collegiate Dictionary, 1981)
Diseases affecting or involving the PARANASAL SINUSES and generally manifesting as inflammation, abscesses, cysts, or tumors.

Arterial thromboembolism in patients with sick sinus syndrome: prediction from pacing mode, atrial fibrillation, and echocardiographic findings. (1/234)

OBJECTIVE: To evaluate whether thromboembolism in sick sinus syndrome can be predicted by pacing mode, atrial fibrillation, or echocardiographic findings. METHODS: Patients were randomised to single chamber atrial (n = 110) or ventricular (n = 115) pacing. They were divided into subgroups with and without brady-tachy syndrome at time of randomisation. The occurrence of atrial fibrillation and thromboembolism during follow up were investigated and compared with echocardiographic findings. RESULTS: The annual risk of thromboembolism was 5.8% in patients with brady-tachy syndrome randomised to ventricular pacing, 3.2% in patients without brady-tachy syndrome randomised to ventricular pacing, 3% in patients with brady-tachy syndrome randomised to atrial pacing, and 1.5% in patients without brady-tachy syndrome randomised to atrial pacing. In atrial paced patients without brady-tachy syndrome at randomisation and without atrial fibrillation during follow up, the annual risk of thromboembolism was 1.4%. Left atrial size measured by M mode echocardiography was of no value in predicting thromboembolism. CONCLUSIONS: Arterial thromboembolism in patients with sick sinus syndrome is very common and is associated primarily with brady-tachy syndrome at randomisation and with ventricular pacing. The risk of thromboembolism is small in atrial paced patients in whom atrial fibrillation has never been documented.  (+info)

Acute performance of steroid-eluting screw-in leads for atrial free wall pacing. (2/234)

The aim of this study was to clarify the acute performance of steroid-eluting screw-in leads in comparison with that of nonsteroid screw-in leads for atrial free wall pacing. In 114 cases (68 males, 46 females, average age 70 years) with atrial free wall pacing by screw-in leads, pacing thresholds and P-wave amplitudes were compared at the time of implantation and 1 week later between 68 cases of nonsteroid and 46 cases of steroid-eluting screw-in leads. No significant differences were seen between the 2 groups at implantation in either voltage or current thresholds measured at pulse widths of 0.1, 0.3, 0.6, 1.0, 2.0 ms, or P-wave amplitudes. Pulse width thresholds at outputs of 2.5 V and 5.0 V were significantly lower for steroid leads 1 week after implantation (2.5 V: 0.34+/-0.27 ms nonsteroid vs. 0.12+/-0.08 ms steroid, p<0.001; 5.0 V: 0.12+/-0.08 ms nonsteroid vs. 0.06+/-0.02 ms steroid, p<0.01). P-wave amplitudes after 1 week were significantly higher for steroid leads (2.6+/-0.7 mV nonsteroid vs 3.0+/-1.2 mV steroid, p<0.001). Threshold rise, including pacing failure, was observed in 15 (22%) of the non-steroid leads, but in only 1 (2%) of the steroid leads. In conclusion, steroid-eluting screw-in leads suppress the acute rise of pacing thresholds in the right atrial free wall and their acute performance is better than that of non-steroid leads. These results suggest that appropriate low-output atrial pacing is feasible immediately after implantation.  (+info)

Exercise-induced uncommon atrioventricular nodal reentrant tachycardia with sick sinus syndrome: a case report. (3/234)

Exercise seldom provokes tachycardia in patients with paroxysmal supraventricular tachycardia (PSVT). This report presents a case of exercise-induced uncommon atrioventricular nodal reentrant tachycardia (AVNRT) with sick sinus syndrome. Treadmill exercise testing provoked AVNRT of long RP' with good reproducibility. Uncommon AVNRT was confirmed by the lack of atrial pre-excitation during PSVT and para-Hisian pacing. The patient has been successfully treated with verapamil and DDD pacing for 5 years.  (+info)

Effect of physiological mechanical perturbations on intact human myocardial repolarization. (4/234)

OBJECTIVE: The objective of this study was to investigate the relationship between acute decreases in right ventricular volume during Valsalva strain (with resultant changes in autonomic neural tone) and measures of local endocardial repolarization time independent of heart rate and autonomic neural tone. METHODS: Patients implanted with a stimulus to T wave (Stim-T) sensing pacemaker specially adapted to output a validate measure of beat to beat local repolarization (n = 9) performed Valsalva manoeuvers (40 mmHg for 15 s) while paced at a cycle length of 500 ms. Stim-T intervals were measured before and after autonomic blockade (Block: 0.03 mg/kg i.v. atropine +/- 0.15 mg/kg propranolol). Right ventricular end diastolic volume was estimated by simultaneous 2D-echocardiography. RESULTS: Without autonomic blockade, compared to baseline, repolarization significantly prolonged during Valsalva strain (1.1 +/- 0.7%) and shortened during release (-1.4 +/- 1.0%). After block, strain related repolarization prolongation was also observed (1.0 +/- 0.6%), with significantly less release related repolarization shortening (-0.8 +/- 0.8%) compared to pre-block (P < 0.05). Right ventricular end diastolic volume decreased during strain by 11 +/- 10 and 9 +/- 16% from baseline, pre- and post-block respectively (P < 0.05). CONCLUSION: In a chronically instrumented human model, an acute physiologic volume reduction modestly prolongs right ventricular repolarization independent of changes in rate or autonomic tone.  (+info)

Concerns about sources of electromagnetic interference in patients with pacemakers. (5/234)

Electromagnetic noise is rapidly increasing in our environment so electromagnetic interference (EMI) with pacemakers (PM) may become a more important problem despite technological improvements in PM. The aim of this study was to evaluate the kinds of EMI which affect the quality of life of PM patients. The participants (1,942 Japanese Association for Pacemaker Patients: Pacemaker-Tomonokai) were asked to respond to a questionnaire about their major EMI troubles, and 1,567 patients (80.7%) responded by mail. The main concerns were from mobile telephones (MT) (39%), magnetic resonance imaging (MRI) (17%), electronic kitchen appliances, automobile engines and high voltage power lines. If possible, PM implantation sites should be carefully selected not only according to the physician's convenience but also considering information on each patient's habits and physical limitations.  (+info)

Regional myocardial blood flow in patients with sick sinus syndrome randomized to long-term single chamber atrial or dual chamber pacing--effect of pacing mode and rate. (6/234)

OBJECTIVES: This study aimed to evaluate regional myocardial blood flow (MBF) and global left ventricular ejection fraction (LVEF) during chronic pacing in patients with sick sinus syndrome (SSS) randomized to either single chamber atrial (AAI) or dual chamber (DDD) pacing. BACKGROUND: Experimental studies indicate that chronic pacing in the right ventricular apex changes regional MBF, thereby compromising left ventricular function. METHODS: Thirty patients (age 74 +/- 10 years) were randomized to AAI (n = 15) or DDD (n = 15) pacemakers. After 22 +/- 7 months of pacing, MBF was quantified with 13N-labeled ammonia positron emission tomography scanning at 60 beats per min and 90 beats per min. Patients in the DDD group furthermore underwent MBF measurement at temporary AAI pacing, 60 beats per min. Myocardial blood flow was assessed in the anterior, lateral, inferior and septal regions, and the global mean MBF was calculated. Left ventricular ejection fraction was determined by echocardiography at pacemaker implantation and at the time of MBF measurements. RESULTS: Myocardial blood flow at rates 60 and 90 beats per min did not differ between the AAI and DDD groups. During temporary AAI pacing in the DDD group, MBF was significantly higher than during DDD pacing in both the inferior (p = 0.001) and septal (p = 0.004) regions and also globally (0.61 +/- 0.15 vs. 0.53 +/- 0.13 mL x g(-1) x min(-1), p = 0.005). In the DDD group, LVEF decreased from pacemaker implantation to time of MBF measurements (0.61 +/- 0.09 vs. 0.56 +/- 0.07, p = 0.013). Left ventricular ejection fraction during temporary AAI pacing at time of MBF measurements was not different from LVEF at pacemaker implantation. CONCLUSIONS: In patients with SSS, chronic DDD pacing reduced inferior, septal and global mean MBF as well as LVEF, as compared with temporary AAI pacing. The LVEF reversed to baseline level during temporary AAI pacing despite 22 months of permanent ventricular pacing preceding it. Augmenting pace rate to 90 beats per min increased MBF equally in the two treatment groups.  (+info)

Exchange of pacing or defibrillator leads following laser sheath extraction of non-functional leads in patients with ipsilateral obstructed venous access. (7/234)

Occlusion of the subclavian or brachiocephalic vein in pacemaker or defibrillator patients prohibits ipsilateral implantation of new leads with standard techniques in the event of lead malfunction. Three patients are presented in whom laser sheath extraction of a non-functional lead was performed in order to recanalise the occluded vein and to secure a route for implantation of new leads. This technique avoids abandoning a useful subpectoral site for pacing or defibrillator therapy. The laser sheath does not affect normally functioning leads at the same site.  (+info)

Permanent pacemaker insertion in a district general hospital: indications, patient characteristics, and complications. (8/234)

This report reviews the experience of permanent pacemaker insertion in a district general hospital (catchment population of 350 000) and makes a comparison with the national database and other hospitals in the UK. METHODS: The records of all patients receiving a permanent pacemaker in the inclusive period January 1996 to December 1998 were reviewed. Data collected included number of patients paced each year, age, sex, indications, and complications. RESULTS: In the three years reviewed 200 patients received new permanent pacemakers, a rate of 190 per million population per year, which is similar to the national implantation rate of permanent pacemakers but lower than that of most European countries (see discussion). The majority of patients paced were elderly (75% were above the age of 70 years). Atrioventricular block (including complete heart block, 45%, and Mobitz type 2 block, 12.5%) was the commonest indication for permanent pacemaker insertion, followed by sick sinus syndrome (25%) and these findings are comparable to those reported previously. However, carotid sinus syndrome was responsible for 16% of the patients paced and this was higher than that reported in the national database (6.5%). Only 1% of the pacemaker modes used was inappropriate and the complication rate was low at 3%. CONCLUSIONS: This report confirms that permanent pacemaker insertion can be effectively and safely provided locally for the increasingly ageing population. The implantation rate both locally and nationally is still much lower than that of some countries in Europe.  (+info)

Sick Sinus Syndrome (SSS) is a term used to describe a group of abnormal heart rhythm disturbances that originates in the sinoatrial node (the natural pacemaker of the heart). This syndrome is characterized by impaired functioning of the sinoatrial node, resulting in various abnormalities such as sinus bradycardia (abnormally slow heart rate), sinus arrest (complete cessation of sinus node activity), and/or sinoatrial exit block (failure of the electrical impulse to leave the sinus node and spread to the atria).

People with SSS may experience symptoms such as palpitations, dizziness, fatigue, shortness of breath, or syncope (fainting) due to inadequate blood supply to the brain caused by slow heart rate. The diagnosis of SSS is typically made based on the patient's symptoms and the results of an electrocardiogram (ECG), Holter monitoring, or event recorder that shows evidence of abnormal sinus node function. Treatment options for SSS may include lifestyle modifications, medications, or implantation of a pacemaker to regulate the heart rate.

An artificial pacemaker is a medical device that uses electrical impulses to regulate the beating of the heart. It is typically used when the heart's natural pacemaker, the sinoatrial node, is not functioning properly and the heart rate is too slow or irregular. The pacemaker consists of a small generator that contains a battery and electronic circuits, which are connected to one or more electrodes that are placed in the heart.

The generator sends electrical signals through the electrodes to stimulate the heart muscle and cause it to contract, thereby maintaining a regular heart rhythm. Artificial pacemakers can be programmed to deliver electrical impulses at a specific rate or in response to the body's needs. They are typically implanted in the chest during a surgical procedure and can last for many years before needing to be replaced.

Artificial pacemakers are an effective treatment for various types of bradycardia, which is a heart rhythm disorder characterized by a slow heart rate. Pacemakers can significantly improve symptoms associated with bradycardia, such as fatigue, dizziness, shortness of breath, and fainting spells.

Sinus arrhythmia is a type of heart rhythm disorder (arrhythmia) where the normal rhythm generated by the sinus node in the heart varies in rate or pattern. The sinus node is the natural pacemaker of the heart and usually sets a steady pace for heartbeats. However, in sinus arrhythmia, the heart rate may speed up or slow down abnormally during breathing in (inspiration) or breathing out (expiration).

When the heart rate increases during inspiration, it is called "inspiratory sinus arrhythmia," and when the heart rate decreases during expiration, it is called "expiratory sinus arrhythmia." Most people experience a mild form of inspiratory sinus arrhythmia, which is considered normal, especially in children and young adults.

However, if the variation in heart rate is significant or accompanied by symptoms such as palpitations, dizziness, shortness of breath, or chest discomfort, it may require medical evaluation and treatment. Sinus arrhythmia can be caused by various factors, including lung disease, heart disease, electrolyte imbalances, or the use of certain medications.

Artificial cardiac pacing is a medical procedure that involves the use of an artificial device to regulate and stimulate the contraction of the heart muscle. This is often necessary when the heart's natural pacemaker, the sinoatrial node, is not functioning properly and the heart is beating too slowly or irregularly.

The artificial pacemaker consists of a small generator that produces electrical impulses and leads that are positioned in the heart to transmit the impulses. The generator is typically implanted just under the skin in the chest, while the leads are inserted into the heart through a vein.

There are different types of artificial cardiac pacing systems, including single-chamber pacemakers, which stimulate either the right atrium or right ventricle, and dual-chamber pacemakers, which stimulate both chambers of the heart. Some pacemakers also have additional features that allow them to respond to changes in the body's needs, such as during exercise or sleep.

Artificial cardiac pacing is a safe and effective treatment for many people with abnormal heart rhythms, and it can significantly improve their quality of life and longevity.

Bradycardia is a medical term that refers to an abnormally slow heart rate, typically defined as a resting heart rate of less than 60 beats per minute in adults. While some people, particularly well-trained athletes, may have a naturally low resting heart rate, bradycardia can also be a sign of an underlying health problem.

There are several potential causes of bradycardia, including:

* Damage to the heart's electrical conduction system, such as from heart disease or aging
* Certain medications, including beta blockers, calcium channel blockers, and digoxin
* Hypothyroidism (underactive thyroid gland)
* Sleep apnea
* Infection of the heart (endocarditis or myocarditis)
* Infiltrative diseases such as amyloidosis or sarcoidosis

Symptoms of bradycardia can vary depending on the severity and underlying cause. Some people with bradycardia may not experience any symptoms, while others may feel weak, fatigued, dizzy, or short of breath. In severe cases, bradycardia can lead to fainting, confusion, or even cardiac arrest.

Treatment for bradycardia depends on the underlying cause. If a medication is causing the slow heart rate, adjusting the dosage or switching to a different medication may help. In other cases, a pacemaker may be necessary to regulate the heart's rhythm. It is important to seek medical attention if you experience symptoms of bradycardia, as it can be a sign of a serious underlying condition.

Heart block is a cardiac condition characterized by the interruption of electrical impulse transmission from the atria (the upper chambers of the heart) to the ventricles (the lower chambers of the heart). This disruption can lead to abnormal heart rhythms, including bradycardia (a slower-than-normal heart rate), and in severe cases, can cause the heart to stop beating altogether. Heart block is typically caused by damage to the heart's electrical conduction system due to various factors such as aging, heart disease, or certain medications.

There are three types of heart block: first-degree, second-degree, and third-degree (also known as complete heart block). Each type has distinct electrocardiogram (ECG) findings and symptoms. Treatment for heart block depends on the severity of the condition and may include monitoring, medication, or implantation of a pacemaker to regulate the heart's electrical activity.

Electrocardiography (ECG or EKG) is a medical procedure that records the electrical activity of the heart. It provides a graphic representation of the electrical changes that occur during each heartbeat. The resulting tracing, called an electrocardiogram, can reveal information about the heart's rate and rhythm, as well as any damage to its cells or abnormalities in its conduction system.

During an ECG, small electrodes are placed on the skin of the chest, arms, and legs. These electrodes detect the electrical signals produced by the heart and transmit them to a machine that amplifies and records them. The procedure is non-invasive, painless, and quick, usually taking only a few minutes.

ECGs are commonly used to diagnose and monitor various heart conditions, including arrhythmias, coronary artery disease, heart attacks, and electrolyte imbalances. They can also be used to evaluate the effectiveness of certain medications or treatments.

Syncope is a medical term defined as a transient, temporary loss of consciousness and postural tone due to reduced blood flow to the brain. It's often caused by a drop in blood pressure, which can be brought on by various factors such as dehydration, emotional stress, prolonged standing, or certain medical conditions like heart diseases, arrhythmias, or neurological disorders.

During a syncope episode, an individual may experience warning signs such as lightheadedness, dizziness, blurred vision, or nausea before losing consciousness. These episodes usually last only a few minutes and are followed by a rapid, full recovery. However, if left untreated or undiagnosed, recurrent syncope can lead to severe injuries from falls or even life-threatening conditions related to the underlying cause.

The sinoatrial (SA) node, also known as the sinus node, is the primary pacemaker of the heart. It is a small bundle of specialized cardiac conduction tissue located in the upper part of the right atrium, near the entrance of the superior vena cava. The SA node generates electrical impulses that initiate each heartbeat, causing the atria to contract and pump blood into the ventricles. This process is called sinus rhythm.

The SA node's electrical activity is regulated by the autonomic nervous system, which can adjust the heart rate in response to changes in the body's needs, such as during exercise or rest. The SA node's rate of firing determines the heart rate, with a normal resting heart rate ranging from 60 to 100 beats per minute.

If the SA node fails to function properly or its electrical impulses are blocked, other secondary pacemakers in the heart may take over, resulting in abnormal heart rhythms called arrhythmias.

A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.

For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.

It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.

Atrial fibrillation (A-tre-al fi-bru-la'shun) is a type of abnormal heart rhythm characterized by rapid and irregular beating of the atria, the upper chambers of the heart. In this condition, the electrical signals that coordinate heartbeats don't function properly, causing the atria to quiver instead of contracting effectively. As a result, blood may not be pumped efficiently into the ventricles, which can lead to blood clots, stroke, and other complications. Atrial fibrillation is a common type of arrhythmia and can cause symptoms such as palpitations, shortness of breath, fatigue, and dizziness. It can be caused by various factors, including heart disease, high blood pressure, age, and genetics. Treatment options include medications, electrical cardioversion, and surgical procedures to restore normal heart rhythm.

NAV1.5, also known as SCN5A, is a specific type of voltage-gated sodium channel found in the heart muscle cells (cardiomyocytes). These channels play a crucial role in the generation and transmission of electrical signals that coordinate the contraction of the heart.

More specifically, NAV1.5 channels are responsible for the rapid influx of sodium ions into cardiomyocytes during the initial phase of the action potential, which is the electrical excitation of the cell. This rapid influx of sodium ions helps to initiate and propagate the action potential throughout the heart muscle, allowing for coordinated contraction and proper heart function.

Mutations in the SCN5A gene, which encodes the NAV1.5 channel, have been associated with various cardiac arrhythmias, including long QT syndrome, Brugada syndrome, and familial atrial fibrillation, among others. These genetic disorders can lead to abnormal heart rhythms, syncope, and in some cases, sudden cardiac death.

Right atrial function refers to the role and performance of the right atrium in the heart. The right atrium is one of the four chambers of the heart and is responsible for receiving deoxygenated blood from the body via the superior and inferior vena cava. It then contracts to help pump the blood into the right ventricle, which subsequently sends it to the lungs for oxygenation.

Right atrial function can be assessed through various methods, including echocardiography, cardiac magnetic resonance imaging (MRI), and electrocardiogram (ECG). Abnormalities in right atrial function may indicate underlying heart conditions such as right-sided heart failure, atrial fibrillation, or other cardiovascular diseases. Proper evaluation and monitoring of right atrial function are essential for effective diagnosis, treatment, and management of these conditions.

The azygos vein is a large, unpaired venous structure in the thoracic cavity of the human body. It begins as the ascending lumbar vein, which receives blood from the lower extremities and abdominal organs. As it enters the thorax through the diaphragm, it becomes the azygos vein and continues to ascend along the vertebral column.

The azygos vein receives blood from various tributaries, including the intercostal veins, esophageal veins, mediastinal veins, and bronchial veins. It then arches over the right mainstem bronchus and empties into the superior vena cava, which returns blood to the right atrium of the heart.

The azygos vein provides an important collateral pathway for venous return in cases where the inferior vena cava is obstructed or occluded. It also plays a role in the spread of certain thoracic diseases, such as tuberculosis and cancer.

The carotid sinus is a small, dilated area located at the bifurcation (or fork) of the common carotid artery into the internal and external carotid arteries. It is a baroreceptor region, which means it contains specialized sensory nerve endings that can detect changes in blood pressure. When the blood pressure increases, the walls of the carotid sinus stretch, activating these nerve endings and sending signals to the brain. The brain then responds by reducing the heart rate and relaxing the blood vessels, which helps to lower the blood pressure back to normal.

The carotid sinus is an important part of the body's autonomic nervous system, which regulates various involuntary functions such as heart rate, blood pressure, and digestion. It plays a crucial role in maintaining cardiovascular homeostasis and preventing excessive increases in blood pressure that could potentially damage vital organs.

Telemetry is the automated measurement and wireless transmission of data from remote or inaccessible sources to receiving stations for monitoring and analysis. In a medical context, telemetry is often used to monitor patients' vital signs such as heart rate, blood pressure, oxygen levels, and other important physiological parameters continuously and remotely. This technology allows healthcare providers to track patients' conditions over time, detect any abnormalities or trends, and make informed decisions about their care, even when they are not physically present with the patient. Telemetry is commonly used in hospitals, clinics, and research settings to monitor patients during procedures, after surgery, or during extended stays in intensive care units.

Cardiac arrhythmias are abnormal heart rhythms that result from disturbances in the electrical conduction system of the heart. The heart's normal rhythm is controlled by an electrical signal that originates in the sinoatrial (SA) node, located in the right atrium. This signal travels through the atrioventricular (AV) node and into the ventricles, causing them to contract and pump blood throughout the body.

An arrhythmia occurs when there is a disruption in this electrical pathway or when the heart's natural pacemaker produces an abnormal rhythm. This can cause the heart to beat too fast (tachycardia), too slow (bradycardia), or irregularly.

There are several types of cardiac arrhythmias, including:

1. Atrial fibrillation: A rapid and irregular heartbeat that starts in the atria (the upper chambers of the heart).
2. Atrial flutter: A rapid but regular heartbeat that starts in the atria.
3. Supraventricular tachycardia (SVT): A rapid heartbeat that starts above the ventricles, usually in the atria or AV node.
4. Ventricular tachycardia: A rapid and potentially life-threatening heart rhythm that originates in the ventricles.
5. Ventricular fibrillation: A chaotic and disorganized electrical activity in the ventricles, which can be fatal if not treated immediately.
6. Heart block: A delay or interruption in the conduction of electrical signals from the atria to the ventricles.

Cardiac arrhythmias can cause various symptoms, such as palpitations, dizziness, shortness of breath, chest pain, and fatigue. In some cases, they may not cause any symptoms and go unnoticed. However, if left untreated, certain types of arrhythmias can lead to serious complications, including stroke, heart failure, or even sudden cardiac death.

Treatment for cardiac arrhythmias depends on the type, severity, and underlying causes. Options may include lifestyle changes, medications, cardioversion (electrical shock therapy), catheter ablation, implantable devices such as pacemakers or defibrillators, and surgery. It is essential to consult a healthcare professional for proper evaluation and management of cardiac arrhythmias.

Atrioventricular (AV) block is a disorder of the electrical conduction system of the heart that causes a delay or interruption in the transmission of electrical signals from the atria (the upper chambers of the heart) to the ventricles (the lower chambers of the heart). This results in an abnormal heart rhythm, also known as an arrhythmia.

There are three degrees of AV block:

1. First-degree AV block: In this type of AV block, there is a delay in the conduction of electrical signals from the atria to the ventricles, but all signals are eventually conducted. This condition may not cause any symptoms and is often discovered during a routine electrocardiogram (ECG).
2. Second-degree AV block: In this type of AV block, some electrical signals from the atria are not conducted to the ventricles. There are two types of second-degree AV block: Mobitz type I and Mobitz type II. Mobitz type I is characterized by a progressive prolongation of the PR interval (the time between the electrical activation of the atria and ventricles) until a QRS complex (which represents the electrical activation of the ventricles) is dropped. Mobitz type II is characterized by a constant PR interval with occasional non-conducted P waves.
3. Third-degree AV block: In this type of AV block, no electrical signals are conducted from the atria to the ventricles. The atria and ventricles beat independently of each other, resulting in a slow heart rate (bradycardia) and an irregular rhythm. This condition can be life-threatening if not treated promptly.

The causes of AV block include aging, heart disease, medications, and certain medical conditions such as hypothyroidism and Lyme disease. Treatment depends on the severity of the condition and may include medication, a pacemaker, or surgery.

The atrioventricular (AV) node is a critical part of the electrical conduction system of the heart. It is a small cluster of specialized cardiac muscle cells located in the lower interatrial septum, near the opening of the coronary sinus. The AV node receives electrical impulses from the sinoatrial node (the heart's natural pacemaker) via the internodal pathways and delays their transmission for a brief period before transmitting them to the bundle of His and then to the ventricles. This delay allows the atria to contract and empty their contents into the ventricles before the ventricles themselves contract, ensuring efficient pumping of blood throughout the body.

The AV node plays an essential role in maintaining a normal heart rhythm, as it can also function as a backup pacemaker if the sinoatrial node fails to generate impulses. However, certain heart conditions or medications can affect the AV node's function and lead to abnormal heart rhythms, such as atrioventricular block or atrial tachycardia.

Ambulatory electrocardiography, also known as ambulatory ECG or Holter monitoring, is a non-invasive method of recording the electrical activity of the heart over an extended period of time (typically 24 hours or more) while the patient goes about their daily activities. The device used to record the ECG is called a Holter monitor, which consists of a small, portable recorder that is attached to the patient's chest with electrodes.

The recorded data provides information on any abnormalities in the heart's rhythm or electrical activity during different stages of activity and rest, allowing healthcare providers to diagnose and evaluate various cardiac conditions such as arrhythmias, ischemia, and infarction. The ability to monitor the heart's activity over an extended period while the patient performs their normal activities provides valuable information that may not be captured during a standard ECG, which only records the heart's electrical activity for a few seconds.

In summary, ambulatory electrocardiography is a diagnostic tool used to evaluate the electrical activity of the heart over an extended period, allowing healthcare providers to diagnose and manage various cardiac conditions.

The cavernous sinus is a venous structure located in the middle cranial fossa, which is a depression in the skull that houses several important nerves and blood vessels. The cavernous sinus is situated on either side of the sphenoid bone, near the base of the skull, and it contains several important structures:

* The internal carotid artery, which supplies oxygenated blood to the brain
* The abducens nerve (cranial nerve VI), which controls lateral movement of the eye
* The oculomotor nerve (cranial nerve III), which controls most of the muscles that move the eye
* The trochlear nerve (cranial nerve IV), which controls one of the muscles that moves the eye
* The ophthalmic and maxillary divisions of the trigeminal nerve (cranial nerve V), which transmit sensory information from the face and head

The cavernous sinus is an important structure because it serves as a conduit for several critical nerves and blood vessels. However, it is also vulnerable to various pathological conditions such as thrombosis (blood clots), infection, tumors, or aneurysms, which can lead to serious neurological deficits or even death.

The heart conduction system is a group of specialized cardiac muscle cells that generate and conduct electrical impulses to coordinate the contraction of the heart chambers. The main components of the heart conduction system include:

1. Sinoatrial (SA) node: Also known as the sinus node, it is located in the right atrium near the entrance of the superior vena cava and functions as the primary pacemaker of the heart. It sets the heart rate by generating electrical impulses at regular intervals.
2. Atrioventricular (AV) node: Located in the interatrial septum, near the opening of the coronary sinus, it serves as a relay station for electrical signals between the atria and ventricles. The AV node delays the transmission of impulses to allow the atria to contract before the ventricles.
3. Bundle of His: A bundle of specialized cardiac muscle fibers that conducts electrical impulses from the AV node to the ventricles. It divides into two main branches, the right and left bundle branches, which further divide into smaller Purkinje fibers.
4. Right and left bundle branches: These are extensions of the Bundle of His that transmit electrical impulses to the respective right and left ventricular myocardium. They consist of specialized conducting tissue with large diameters and minimal resistance, allowing for rapid conduction of electrical signals.
5. Purkinje fibers: Fine, branching fibers that arise from the bundle branches and spread throughout the ventricular myocardium. They are responsible for transmitting electrical impulses to the working cardiac muscle cells, triggering coordinated ventricular contraction.

In summary, the heart conduction system is a complex network of specialized muscle cells responsible for generating and conducting electrical signals that coordinate the contraction of the atria and ventricles, ensuring efficient blood flow throughout the body.

The heart atria are the upper chambers of the heart that receive blood from the veins and deliver it to the lower chambers, or ventricles. There are two atria in the heart: the right atrium receives oxygen-poor blood from the body and pumps it into the right ventricle, which then sends it to the lungs to be oxygenated; and the left atrium receives oxygen-rich blood from the lungs and pumps it into the left ventricle, which then sends it out to the rest of the body. The atria contract before the ventricles during each heartbeat, helping to fill the ventricles with blood and prepare them for contraction.

Heart rate is the number of heartbeats per unit of time, often expressed as beats per minute (bpm). It can vary significantly depending on factors such as age, physical fitness, emotions, and overall health status. A resting heart rate between 60-100 bpm is generally considered normal for adults, but athletes and individuals with high levels of physical fitness may have a resting heart rate below 60 bpm due to their enhanced cardiovascular efficiency. Monitoring heart rate can provide valuable insights into an individual's health status, exercise intensity, and response to various treatments or interventions.

The maxillary sinuses, also known as the antrums of Highmore, are the largest of the four pairs of paranasal sinuses located in the maxilla bones. They are air-filled cavities that surround the nasolacrimal duct and are situated superior to the upper teeth and lateral to the nasal cavity. Each maxillary sinus is lined with a mucous membrane, which helps to warm, humidify, and filter the air we breathe. Inflammation or infection of the maxillary sinuses can result in conditions such as sinusitis, leading to symptoms like facial pain, headaches, and nasal congestion.

"Sick leave" is not a medical term, but rather a term used in the context of employment and human resources. It refers to the time off from work that an employee is allowed to take due to illness or injury, for which they may still receive payment. The specific policies regarding sick leave, such as how much time is granted and whether it is paid or unpaid, can vary based on the employer's policies, labor laws, and collective bargaining agreements.

Paranasal sinus diseases refer to a group of medical conditions that affect the paranasal sinuses, which are air-filled cavities located within the skull near the nasal cavity. These sinuses include the maxillary, frontal, ethmoid, and sphenoid sinuses.

Paranasal sinus diseases can be caused by a variety of factors, including viral, bacterial, or fungal infections, allergies, structural abnormalities, or autoimmune disorders. Some common paranasal sinus diseases include:

1. Sinusitis: Inflammation or infection of the sinuses, which can cause symptoms such as nasal congestion, thick nasal discharge, facial pain or pressure, and reduced sense of smell.
2. Nasal polyps: Soft, benign growths that develop in the lining of the nasal passages or sinuses, which can obstruct airflow and cause difficulty breathing through the nose.
3. Sinonasal tumors: Abnormal growths that can be benign or malignant, which can cause symptoms such as nasal congestion, facial pain, and bleeding from the nose.
4. Sinus cysts: Fluid-filled sacs that form in the sinuses, which can cause symptoms similar to those of sinusitis.
5. Fungal sinusitis: Infection of the sinuses with fungi, which can cause symptoms such as nasal congestion, facial pain, and thick, discolored mucus.

Treatment for paranasal sinus diseases depends on the underlying cause and severity of the condition. Treatment options may include medications, such as antibiotics, antihistamines, or corticosteroids, as well as surgical intervention in more severe cases.

... (SND), also known as sick sinus syndrome (SSS), is a group of abnormal heart rhythms (arrhythmias) ... Tachycardia-bradycardia syndrome is a variant of sick sinus syndrome in which the arrhythmia alternates between fast and slow ... and other antiarrhythmics can alter sinus node function to create an arrhythmia such as sick sinus syndrome. Electrolyte ... Semelka M, Gera J, Usman S (15 May 2013). "Sick sinus syndrome: a review". American Family Physician. 87 (10): 691-6. PMID ...
... is contraindicated in sick sinus syndrome. It should also not be used concomitantly with potent inhibitors of CYP3A4 ... It is used for the symptomatic treatment of chronic stable angina pectoris in patients with normal sinus rhythm who cannot take ... It is also being used off-label in the treatment of inappropriate sinus tachycardia. Ivabradine stands as a pharmacological ... It has been used experimentally for the treatment of postural orthostatic tachycardia syndrome in patients with long COVID. ...
Some humans with bradycardia and Sick sinus syndrome have been shown to have mutations in their HCN4 gene. The role of HCN ... "A Functional Assay for Sick Sinus Syndrome Genetic Variants". Cellular Physiology and Biochemistry. 42 (5): 2021-2029. doi: ... GeneReviews/NIH/NCBI/UW entry on Brugada syndrome HCN4+protein,+human at the U.S. National Library of Medicine Medical Subject ... Nof E, Antzelevitch C, Glikson M (Jan 2010). "The Contribution of HCN4 to normal sinus node function in humans and animal ...
The problem in sick sinus syndrome is that the SA node is not functioning properly and is causing an irregular heartbeat. ... Currently the treatment for sick sinus syndrome is to remove the SA nodal cells that are not functioning properly (?) and to ... Tbx18 gene therapy is aimed at treating a group of arrhythmias known as sick sinus syndrome. In a healthy heart, sinoatrial (SA ... Long-Term Survival After Permanent Pacemaker Implantation for Sick Sinus Syndrome. The American Journal of Cardiology. 74: 1016 ...
Sick sinus syndrome* is most commonly seen in female Miniature Schnauzers. It is characterized by sinoatrial node dysfunction ... Dermal fragility syndrome, also known as Ehlers-Danlos-like syndrome, is a rare condition in dogs characterized by increased ... Electrocardiogram findings include sinus bradycardia, sinus arrest, sinoatrial heart block, and atrial tachycardia. The major ... White dog shaker syndrome causes full body tremors in small, white dog breeds. It is most common in West Highland White ...
Promoting Understanding of Sick Sinus Syndrome". Circulation. 115 (14): 1921-1932. doi:10.1161/CIRCULATIONAHA.106.616011. PMID ... Promoting Understanding of Sick Sinus Syndrome". Circulation. 115 (14): 1921-1932. doi:10.1161/CIRCULATIONAHA.106.616011. PMID ... Silverman, M. E.; Hollman, A. (1 October 2007). "Discovery of the sinus node by Keith and Flack: on the centennial of their ... and the subsequent discovery of the sinus node which completed the system. He credited Tawara for connecting the bundle with ...
Sick sinus syndrome, a sinus node dysfunction, causing alternating bradycardia and tachycardia. Often there is a long pause ( ... Especially in people with hypersensitive carotid sinus syndrome this response can cause syncope or presyncope. Heart-related ... such as long QT syndrome and Brugada syndrome. Heart related causes also often have little history of a prodrome. Low blood ... such as long QT syndrome and Brugada syndrome. Heart related causes also often have little history of a prodrome. Low blood ...
Studies have shown that patients with Pacemaker syndrome and/or with sick sinus syndrome are at higher risk of developing fatal ... Santini M, Alexidou G, Ansalone G, Cacciatore G, Cini R, Turitto G (March 1990). "Relation of prognosis in sick sinus syndrome ... "Prospective randomised trial of atrial versus ventricular pacing in sick-sinus syndrome". Lancet. 344 (8936): 1523-8. doi: ... In the preimplantation period, two variables are predicted to predispose to the syndrome. First is low sinus rate, and second ...
... has also been identified as a susceptibility gene for sick sinus syndrome. A missense mutation at Arg721Trp was identified ... atrial septal defects and sick sinus syndrome. MHC-α is a 224 kDa protein composed of 1939 amino acids. The MYH6 gene is ... "A rare variant in MYH6 is associated with high risk of sick sinus syndrome". Nature Genetics. 43 (4): 316-20. doi:10.1038/ng. ... "Novel mutation in the α-myosin heavy chain gene is associated with sick sinus syndrome". Circulation: Arrhythmia and ...
It is contraindicated if there has been a past history of angioedema; heart conduction disorders (e.g. sick sinus syndrome, ... Also: Raynaud's syndrome, intermittent claudication, epilepsy, depression, Parkinson's disease, glaucoma. Use in pregnancy is ... In addition, it demonstrates favourable effects on parameters of the insulin resistance syndrome, apparently independent of ...
"Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)". Journal of Clinical ... Scott, C. I. (1971). "Unusual facies, joint hypermobility, genital anomaly and short stature: A new dysmorphic syndrome". Birth ... San Diego Supercomputer Center (SDSC). Chen, Harold (2019-11-10). Buehler, Bruce (ed.). "Genetics of Marfan Syndrome". Medscape ...
Excessively slow heart rate can also occur, such as in sick sinus syndrome, with ensuing fatigue and dizziness. Wild-type ... Some patients may develop carpal tunnel syndrome as an initial symptom of wild-type transthyretin amyloid. There appears to be ... "High prevalence of wild-type transthyretin deposition in patients with idiopathic carpal tunnel syndrome: a common cause of ... carpal tunnel syndrome in the elderly". Human Pathology (Submitted manuscript). 42 (11): 1785-91. doi:10.1016/j.humpath.2011.03 ...
"Effects of Permanent Pacemaker and Oral Theophylline in Sick Sinus Syndrome: The THEOPACE Study: A Randomized Controlled Trial ...
... cardiac arrhythmia syndrome known as long QT syndrome 4 as well as sick sinus syndrome; mutations have also been associated to ... cardiac arrhythmia syndrome known as long QT syndrome, type 4, also known as ankyrin-B syndrome which can be described as an ... Robaei, D; Ford, T; Ooi, SY (February 2015). "Ankyrin-B syndrome: a case of sinus node dysfunction, atrial fibrillation and ... "Atrial fibrillation and sinus node dysfunction in human ankyrin-B syndrome: a computational analysis". American Journal of ...
... dual-chamber pacemakers may reduce the incidence of complications in people with sick sinus syndrome and atrioventricular block ... a sinus rhythm) represent the first rhythm. The QRS complexes with a regular R-to-R interval represent the second rhythm. The ... a potential side effect is pacemaker syndrome, and may necessitate the use of a biventricular pacemaker, which has an ...
... severe cardiac arrhythmia and sick sinus syndrome. People with peptic ulcer disease or taking NSAIDs should use with caution ... CADASIL syndrome, and Down syndrome. A three-year National Institutes of Health trial in people with mild cognitive impairment ... In those with Tourette syndrome and ADHD, donepezil may reduce tics while it had no effect on ADHD's symptoms. Donepezil, along ...
... sick sinus syndrome, and unstable angina. Several patient groups are at a heightened risk of side effects from olanzapine and ... Postinjection delirium/sedation syndrome (PDSS) is a rare syndrome that is specific to the long-acting injectable formulation ... Haddad P, Haddad PM, Dursun S, Deakin B (2004). Adverse Syndromes and Psychiatric Drugs: A Clinical Guide. OUP Oxford. pp. 207- ... It has also been used for Tourette syndrome and stuttering. Olanzapine has been studied for the treatment of hyperactivity, ...
... sick sinus syndrome, or a recent myocardial infarction, among others. This medication will be given intravenously for your ... agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm ...
... such as sick sinus syndrome), Roemheld syndrome, sleep apnea Physiological causes: Increased vagal tone, increased intracranial ... Sinus tachycardia Long QT syndrome Hafeez Y, Grossman SA (2020). "Sinus Bradycardia". StatPearls. Treasure Island (FL): ... Sinus bradycardia is a sinus rhythm with a reduced rate of electrical discharge from the sinoatrial node, resulting in a ... carotid sinus syndrome, eating disorders (such as anorexia nervosa), rhodotoxin poisoning, hypothermia, hypothyroidism, ...
... is relatively contraindicated in the presence of sick sinus syndrome, atrioventricular node conduction disturbances, ... Gabrielli A, Gallagher TJ, Caruso LJ, Bennett NT, Layon AJ (October 2001). "Diltiazem to treat sinus tachycardia in critically ... Diltiazem may paradoxically increase ventricular rate in patients with Wolff-Parkinson-White syndrome because of accessory ...
Sick Sinus Syndrome with Mastic Scum, and Swarming of Virulency with Ingrowing. In 1997, the band released a compilation EP ... Sick Sinus Syndrome - split with Mastic Scum (1996) Swarming of Virulency - split with Ingrowing (1996) Hungry Urinary URN - ... And Some Sick Parts Rotting Out There (compilation, 2010) Full Equality!? (1998) We Are the Metal - limited edition issued with ...
... sick sinus syndrome, and aortic and intracranial aneurysm. Among their noteworthy recent discoveries is a rare variant in the ... "A rare variant in MYH6 is associated with high risk of sick sinus syndrome," Nature Genetics (subscription required), Volume 43 ... Genes linked to rarer syndromes had been identified in isolated families in Sardinia, Newfoundland, Finland and elsewhere, and ...
427.8 Other specified cardiac dysrhythmias 427.81 Sick sinus syndrome 427.89 Sinus bradycardia, NOS 427.9 Cardiac dysrhythmia ... Basilar artery syndrome 435.1 Vertebral artery syndrome 435.2 Subclavian steal syndrome 435.3 Vertebrobasilar artery syndrome ... 411 Other acute and subacute forms of ischemic heart disease 411.0 Postmyocardial infarction syndrome 411.1 Intermediate ... Acute febrile mucocutaneous lymph node syndrome 446.5 Giant Cell arteritis(Temporal Arteritis) 447 Other disorders of arteries ...
... hyperthyroid Endocarditis Sick sinus syndrome ABCD:p. 30 Anti-coagulate Beta-block to control rate Cardiovert Digoxin 3 D's:p. ... Infections Acute renal failure Cardiac infarction Rheumatic fever Injury Neoplasms Dressler's syndrome PericarditiS:p. 34 PR ... Valve disease Aneurysm of Ventricles Dressler's Syndrome thromboEmbolism (mural thrombus) Recurrence/ mitral Regurgitation DUST ...
... correlating with sick sinus syndrome. Prolonged episodes of atrial fibrillation have been shown to correlate with prolongation ... Inherited arrhythmic syndromes (congenital long QT syndrome, short QT syndrome, Brugada syndrome) Non-familial AF associated ... short QT syndrome, Wolff Parkinson White syndrome, and other forms of supraventricular tachycardia (e.g., AV nodal reentrant ... An important theory is that the regular impulses produced by the sinus node for a normal heartbeat are overwhelmed by rapid ...
... as well as heart problems such as sinus bradycardia, second- or third-degree atrioventricular block, sick sinus syndrome, and ...
Heart conditions such as dilated cardiomyopathy, where the heart becomes weakened and enlarged, and sick sinus syndrome, which ... American Cockers are also prone to canine epilepsy and the related condition known as Rage Syndrome. The latter is a form of ...
... sick sinus syndrome (unless a permanent pacemaker is in place), severe hepatic impairment (Child-Pugh > B) and in patients who ... Heart block greater than first degree Patients with cardiogenic shock Decompensated cardiac failure Sick sinus syndrome (unless ...
... sinus node disease (SND) or sick sinus syndrome. Where the problem is atrioventricular block (AVB) the pacemaker is required to ... Often, for patients in normal sinus rhythm, there is also a lead in the right atrium to facilitate synchrony with the atrial ... Another possible complication called twiddler's syndrome occurs when a patient manipulates the pacemaker and causes the leads ... or the coronary sinus, depending on the type of pacemaker required. Surgery is typically completed within 30 to 90 minutes. ...
... sick sinus syndrome, sustained atrial flutter, recent myocardial infarction, chronic myocardial infarction together with ... "acute ischemic cerebrovascular syndrome" (modeled after heart attack and acute coronary syndrome, respectively), to reflect the ... The 24-hour limit divides stroke from transient ischemic attack, which is a related syndrome of stroke symptoms that resolve ... Cerebral venous sinus thrombosis. Stroke without an obvious explanation is termed cryptogenic stroke (idiopathic); this ...
... also known as sinus node dysfunction) is a group of related heart conditions that can affect how the heart beats . Explore ... Genetic Testing Registry: Sick sinus syndrome 2, autosomal dominant *Genetic Testing Registry: Sick sinus syndrome 3, ... medlineplus.gov/genetics/condition/sick-sinus-syndrome/ Sick sinus syndrome. ... Sick sinus syndrome (also known as sinus node dysfunction) is a group of related heart conditions that can affect how the heart ...
Sick sinus syndrome is also called sinus node dysfunction. What causes it? Sick sinus syndrome can occur for various reasons. ... Sick sinus syndrome is the name given to a group of arrhythmias that occur because the normal pacemaker of the heart (the sinus ... Sick sinus syndrome is also called sinus node dysfunction. What causes it?. Sick sinus syndrome can occur for various reasons. ... What is an example of sick sinus syndrome?. One example of sick sinus syndrome is tachy-brady syndrome. ...
... (SSS) is a type of abnormal heartbeat, or arrhythmia. If you have SSS, you may have episodes when your ... Sick Sinus Syndrome. What is sick sinus syndrome? Sick sinus syndrome (SSS) is a disease that affects the hearts natural ... Key points about sick sinus syndrome. * Sick sinus syndrome (SSS) is generally a slow heart rate, but sometimes it can be too ... Who is at risk for sick sinus syndrome? Sick sinus syndrome affects men and women equally and can occur at any age. But most ...
It\s sometimes called sinus node disease or sinus node dysfunction. Sick sinus syndrome is a type of bradycardia, a condition ... Sick sinus syndrome (SSS) is a heart rhythm disorder that affects the sinus node, the heart\s natural pacemaker. ... Sick Sinus Syndrome Icd 10. Icd10cm Code For Sinus Rhythm from icd-faq.com. What is Sick Sinus Syndrome?. Sick sinus syndrome ( ... People with sick sinus syndrome may also feel tired or weak. What Causes Sick Sinus Syndrome?. Sick sinus syndrome is caused by ...
Sick sinus syndrome is a clinical syndrome characterized by sinus node dysfunction. It presents in elderly patients with ... Sick Sinus Syndrome: Sinus Node Dysfunction in the Elderly Sandeep Khanna, M.D.; Sandeep Khanna, M.D. ... Sandeep Khanna, Roshni Sreedharan, Carlos Trombetta, Kurt Ruetzler; Sick Sinus Syndrome: Sinus Node Dysfunction in the Elderly ... Sinus Nodal Function and Risk for Atrial Fibrillation after Coronary Artery Bypass Graft Surgery Anesthesiology (May 2000) ...
Familial sick sinus syndrome in two siblings. Turk J Pediatr. 1993 Jan-Mar; 35(1):59-64. ...
Answer: A. Sinus node dysfunction Tachy-brady syndrome is a variant of sick sinus syndrome (SSS), where there is intrinsic ... Both atrial fibrillation and sick sinus syndrome (a subset of which is also known as "tachy-brady" syndrome) are more common in ... Atrial Fibrillation and Sick Sinus Syndrome: A Clinical Catch-22. November 2, 2016. Payal Kohli, MD ... In this case, the rapid discharge of AF can result in sinus node "fatigue" and exacerbation of bradyarrhythmias or post- ...
Sick sinus syndrome is also known as sinus node dysfunction or sinus node disease.Sick sinus syndrome Treatment Hyderabad The ... sinus node) to generate a heart rate that matches the bodys needs. It causes irregular heart rhythms (arrhythmias). ... overview Sick sinus syndrome is the inability of the natural pacemaker ( ... Sick sinus syndrome is also known as sinus node dysfunction or sinus node disease.Sick sinus syndrome Treatment Hyderabad ...
We use cookies to ensure that we give you the best experience on our website. If you click Accept all cookies well assume that you are happy to receive all cookies and you wont see this message again. If you click Reject all non-essential cookies only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click Find out more for information on how to change your cookie settings. ...
... Hye Yun Kim, Do Young Yoon, Dong Sun Kim, Ji Sun Kwon, ... We diagnosed as a sick sinus syndrome (SSS) presented with EHS. We suggest SSS should be considered with the elderly patients ... Exploding head syndrome (EHS) is a rare syndrome experienced with explosive noise happening in a head. A 78 year old man ... A Case of Sick Sinus Syndrome Presenting as Exploding Head Syndrome. ...
Sinus node dysfunction (SND), also known as sick sinus syndrome (SSS), is a group of abnormal heart rhythms (arrhythmias) ... Tachycardia-bradycardia syndrome is a variant of sick sinus syndrome in which the arrhythmia alternates between fast and slow ... and other antiarrhythmics can alter sinus node function to create an arrhythmia such as sick sinus syndrome. Electrolyte ... Semelka M, Gera J, Usman S (15 May 2013). "Sick sinus syndrome: a review". American Family Physician. 87 (10): 691-6. PMID ...
Sick sinus syndrome. This imprecise diagnosis is…. Ventricular Arrhythmias. • Heart Disease articles • Dec 19 05. ... Acute coronary syndromes. • Heart Disease articles • Dec 19 05. Introduction Acute coronary syndromes comprise the spectrum of ... The heart may be involved in a number of systemic syndromes. Many of these have been mentioned briefly in prior subsections of ... Abnormalities of conduction can occur between the sinus node and atrium, within the atrioventricular node, and in the ...
Read this chapter of Syndromes: Rapid Recognition and Perioperative Implications, 2e online now, exclusively on ... "Sick Sinus Syndrome." Syndromes: Rapid Recognition and Perioperative Implications, 2e Bissonnette B, Luginbuehl I, Engelhardt T ... Attempt to define etiology of the Sick Sinus Syndrome in the individual patient may be impossible. If the syndrome is newly ... Sick Sinus Syndrome. In: Bissonnette B, Luginbuehl I, Engelhardt T. Bissonnette B, & Luginbuehl I, & Engelhardt T(Eds.),Eds. ...
... sick sinus syndrome and Wolf-Parkinson-White Syndrome. ... Sick sinus syndrome. When the sinus node (also called the ... This is referred to as sick sinus syndrome.. In this condition, the heart rate can fluctuate between an overly slow rate ( ... Sinus arrhythmia is normal. Wolff-Parkinson-White Syndrome (WPW). In this disorder, the electrical pathways between the hearts ... Sinus arrhythmia. Common in children, this type of irregular heart rhythm refers to changes in the heart rate during breathing ...
The patient was diagnosed with sick sinus syndrome based on repeated postoperative sinus arrest, which could have resulted in ... Sick sinus syndrome diagnosed after a sinus arrest during treatment for zygomatic fracture: a case report. ... Sick sinus syndrome diagnosed after a sinus arrest during treatment for zygomatic fracture ... There are no reports of maxillofacial trauma leading to a diagnosis of sick sinus syndrome. The purpose of this case report is ...
Sick Sinus Syndrome. *Sinus Bradycardia. *Sinus Tachycardia. *Subacute Endocarditis. *Supraventricular Tachycardia. *Syncope ...
Sick Sinus Syndrome. *Sickle Cell Disease. *Sinus Bradycardia. *Sinus Tachycardia. *Skin Ulcer ...
Sick sinus syndrome. The sinus node sets the pace of the heart. If the node doesnt work properly, the heart rate may switch ... Sick sinus syndrome can be caused by scarring near the sinus node that slows, disrupts or blocks heartbeat signals. The ... The hearts electrical signals start in a group of cells at the top of the heart called the sinus node. They pass through a ... In a typical heartbeat, a tiny cluster of cells at the sinus node sends out electrical signals, called impulses. The signals go ...
Sick sinus syndrome. * Decompensated cardiac failure. * Pheochromocytoma (can be given in combination with an alpha blocker if ... The left and right coronary arteries can arise from the noncoronary sinus or the opposite sinus. In these cases, the arteries ... More than 90% drain into the right atrium, coronary sinus, or right ventricle. [77] On CCTA, contrast opacification of the ... 53] state that prospective ECG triggering should be used in patients who have stable sinus rhythm and low heart rates ( ...
Sinus bradycardia is a heart rhythm thats slower than expected, but otherwise normal. Severe cases that cause symptoms are ... Sick sinus syndrome. This is when your hearts natural pacemaker, a cluster of cells called the sinoatrial (SA) node, ... An electrocardiogram example of sinus bradycardia.. What is sinus bradycardia?. Sinus bradycardia is a heart rhythm thats ... Sinus Bradycardia. Sinus bradycardia is a heart rhythm where your heart beats slower than expected (under 60 beats per minute ...
Sick sinus syndrome. ( 4) *Severe bradycardia (unless permanent pacemaker in place). ( 4) ... 5.14 Intraoperative Floppy Iris Syndrome. Intraoperative Floppy Iris Syndrome (IFIS) has been observed during cataract surgery ... 5.14 Intraoperative Floppy Iris Syndrome 6 ADVERSE REACTIONS 6.1 Clinical Studies Experience 6.2 Postmarketing Experience 7 ... Patients with a history of a serious hypersensitivity reaction (e.g., Stevens-Johnson syndrome, anaphylactic reaction, ...
Sick-sinus syndrome. Severe peripheral arterial circulatory disorders. Hydrochlorothiazide. Hydrochlorothiazide is ... Body as a Whole: Fatigue or lethargy and flu syndrome have each been reported in about 10 in 100 patients. ... The oculomucocutaneous syndrome associated with the beta-blocker practolol has not been reported with metoprolol. ... Animal and human experiments indicate that metoprolol slows the sinus rate and decreases AV nodal conduction. ...
If an obvious cause is present, such as complete heart block or sick sinus syndrome, then the morbidity or mortality is ... Junctional rhythms are common in patients with sick sinus syndrome or in patients who have significant bradycardia that allows ... Changes in autonomic tone or the presence of sinus node disease that is causing an inappropriate slowing of the sinus node may ... Less commonly, the AV junction develops abnormal automaticity and exceeds the sinus node rate at a time when the sinus rate ...
Sick Sinus Syndrome ... Padmanabhan has experience treating conditions like Sinus ... Padmanabhan frequently treats the following conditions: Sinus Bradycardia, Rheumatic Aortic Valve Disorders and Mitral and ...
Sick sinus syndrome - Sino-atrial block - Unstable or acute heart failure - Pacemaker dependent (heart rate imposed exclusively ... Use in patients with congenital QT syndrome or treated with QT prolonging medicinal products The use of ivabradine in patients ... Ivabradine is indicated in chronic heart failure NYHA II to IV class with systolic dysfunction, in patients in sinus rhythm and ... There is no evidence of risk of (excessive) bradycardia on return to sinus rhythm when pharmacological cardioversion is ...
have sick sinus syndrome. What side effects are possible with this medication?. Many medications can cause side effects. A side ...
Sick sinus syndrome. *Supraventricular tachycardia (a collection of abnormal heart rhythms that start in the upper chambers of ...
  • Sick sinus syndrome (also known as sinus node dysfunction) is a group of related heart conditions that can affect how the heart beats . (medlineplus.gov)
  • Sick sinus syndrome is also called sinus node dysfunction. (wellspan.org)
  • It\'s sometimes called sinus node disease or sinus node dysfunction. (kat1055.com)
  • Sick sinus syndrome is a clinical syndrome characterized by sinus node dysfunction. (silverchair.com)
  • Anesthesia can unmask sinus node dysfunction, which then manifests as significant atrial dysrhythmias and "rarely" asystole. (silverchair.com)
  • Autonomic imbalances from central neuraxial anesthesia-induced sympathectomy and use of sympatholytic drugs, such as propofol, remifentanil, dexmedetomidine, or vecuronium, during general anesthesia can unveil latent sinus node dysfunction and trigger life-threatening atropine-resistant bradyarrhythmias. (silverchair.com)
  • As transcutaneous pacing may not provide reliable electrical capture, it is advisable to institute temporary transvenous pacing before anesthesia induction when sinus node dysfunction is suspected. (silverchair.com)
  • Tachy-brady syndrome is a variant of sick sinus syndrome (SSS), where there is intrinsic sinus node dysfunction that leads to alternating slow and fast heart rates. (patientcareonline.com)
  • Sinus node dysfunction (SND), also known as sick sinus syndrome (SSS), is a group of abnormal heart rhythms (arrhythmias) usually caused by a malfunction of the sinus node, the heart's primary pacemaker. (wikipedia.org)
  • Often sinus node dysfunction produces no symptoms, especially early in the disease course. (wikipedia.org)
  • The most common complication of sinus node dysfunction is the development of tachycardia-bradycardia syndrome with abnormal atrial rhythms such as atrial tachycardia, atrial fibrillation, and flutter. (wikipedia.org)
  • Sinus node dysfunction has a close association with the presence of atrial fibrillation due to their shared etiology of remodeling. (wikipedia.org)
  • Sinus node dysfunction can be caused by intrinsic and extrinsic factors that affect the normal functioning of the sinus node. (wikipedia.org)
  • Intrinsic causes can include degeneration, dysfunction, or remodeling of the sinus node while extrinsic causes can create or worsen underlying atrial arrhythmias. (wikipedia.org)
  • Intrinsic causes tend to be responsible for permanent sinus node dysfunction while extrinsic causes are more commonly temporary. (wikipedia.org)
  • Inherited sinus node dysfunction has been associated with mutations of the gene responsible for the formation of the alpha subunit of the sodium channel (SCN5A). (wikipedia.org)
  • The primary 12-lead electrocardiogram (ECG) finding in sinus node dysfunction is inappropriate sinus bradycardia. (wikipedia.org)
  • Sinus node dysfunction can also present with sudden sinus arrest with or without junctional escape, sinoatrial block, prolonged asystolic period followed by tachycardias, or tachycardia-bradycardia syndrome presenting as various atrial arrhythmias such as atrial fibrillation, flutter, tachycardia, or paroxysmal supraventricular tachycardia. (wikipedia.org)
  • Diagnosing sinus node dysfunction requires clinical symptoms as well as ECG abnormalities. (wikipedia.org)
  • If Holter or telemetry monitoring fails to identify ECG changes and suspicion of sinus node dysfunction remains high due to severe symptoms or episodes of syncope, implantable loop recorders should be considered for extended monitoring up to 24 months. (wikipedia.org)
  • Exercise stress tests can be utilized to identify intrinsic causes of sinus node dysfunction. (wikipedia.org)
  • Pacemaker implantation is the primary treatment modality of symptomatic sinus node dysfunction. (wikipedia.org)
  • The goal of this treatment modality is to relieve symptoms associated with sinus node dysfunction and improve quality of life. (wikipedia.org)
  • Junctional bradycardia due to profound sinus node dysfunction. (medscape.com)
  • Ivabradine is indicated in chronic heart failure NYHA II to IV class with systolic dysfunction, in patients in sinus rhythm and whose heart rate is ≥ 75 bpm, in combination with standard therapy including beta-blocker therapy or when beta-blocker therapy is contraindicated or not tolerated. (medicines.org.uk)
  • Sinus node dysfunction (SND) is a major clinically relevant disease which is associated with sudden cardiac death and requires surgical implantation of electrical pacemaker devices. (cipsm.de)
  • Diastolic dysfunction is the predominant cardiac abnormality in this syndrome, which is associated with increased risk of hospitalisation and death. (bmj.com)
  • Sinus node dysfunction refers to a number of conditions causing physiologically inappropriate atrial rates. (msdmanuals.com)
  • Many patients with sinus node dysfunction are asymptomatic, but depending on the heart rate, all the symptoms of bradycardias and tachycardias can occur. (msdmanuals.com)
  • AF), and the underlying sinus node dysfunction manifests only after conversion to sinus rhythm. (msdmanuals.com)
  • As we get older, scarring of the sinus node can occur and cause this syndrome. (wellspan.org)
  • This combination of fast and slow heart rhythm is called tachy-brady syndrome (short for tachycardia-bradycardia). (brighamandwomens.org)
  • Sick sinus syndrome (SSS) is a heart rhythm disorder that affects the sinus node, the heart\'s natural pacemaker. (kat1055.com)
  • You order a 48h holter monitor and it returns, showing multiple bursts of AF with rapid ventricular response (RVR) followed by episodes of conversion back to sinus rhythm with post-conversion pauses (longest 3.2 seconds). (patientcareonline.com)
  • In this case, the rapid discharge of AF can result in sinus node "fatigue" and exacerbation of bradyarrhythmias or post-conversion (to sinus rhythm) pauses. (patientcareonline.com)
  • Usually the sinus node creates a constant rhythm of electrical impulses. (noseplasticsurgery.in)
  • Many people with sick sinus syndrome ultimately need a pacemaker to keep their heart rhythm stable. (noseplasticsurgery.in)
  • Your heart's rhythm is usually controlled by the sinus node, an area of ​​specialized cells in the upper right chamber of the heart (atrium). (noseplasticsurgery.in)
  • In the presence of sinus arrest or extreme sinus bradycardia, a junctional escape rhythm may develop. (mhmedical.com)
  • Sinus bradycardia is a heart rhythm where your heart beats slower than expected (under 60 beats per minute for adults) but otherwise works normally. (clevelandclinic.org)
  • Sinus bradycardia is a heart rhythm that's slower than expected (fewer than 60 beats per minute in an adult) but is otherwise normal. (clevelandclinic.org)
  • Sinus bradycardia means your heart is beating slowly but still using a sinus rhythm. (clevelandclinic.org)
  • During sinus rhythm, every heartbeat you have starts in the sinoatrial (SA) node, a cluster of electrically active cells near the top of your heart. (clevelandclinic.org)
  • Sinus rhythm means your sinus node is setting the tempo for your heartbeat, which is normal and expected. (clevelandclinic.org)
  • 60) is a narrow complex rhythm that often supersedes a clinically bradycardic sinus node rate (see images below). (medscape.com)
  • Accelerated junctional rhythm is a result of enhanced automaticity of the AVN that supersedes the sinus node rate. (medscape.com)
  • During this rhythm, the AVN is firing faster than the sinus node, resulting in a regular narrow complex rhythm. (medscape.com)
  • Changes in autonomic tone or the presence of sinus node disease that is causing an inappropriate slowing of the sinus node may exacerbate this rhythm. (medscape.com)
  • Ivabradine is indicated for the symptomatic treatment of chronic stable angina pectoris in coronary artery disease adults with normal sinus rhythm and heart rate ≥ 70 bpm. (medicines.org.uk)
  • Normal sinus rhythm is usually not affected by verapamil HCl. (drugs.com)
  • In some cases, the heartbeat rapidly switches from being too fast to being too slow, a condition known as tachycardia-bradycardia syndrome. (medlineplus.gov)
  • In tachy-brady syndrome, also called tachycardia-bradycardia syndrome, the heart sometimes beats too quickly (tachy) and sometimes beats too slowly (brady). (wellspan.org)
  • Tachycardia-bradycardia syndrome is a variant of sick sinus syndrome in which the arrhythmia alternates between fast and slow heart rates. (wikipedia.org)
  • Signs and symptoms usually appear in more advanced disease and more than 50% of patients will present with syncope or transient near-fainting spells as well as bradycardias that are accompanied by rapid heart rhythms, referred to as tachycardia-bradycardia syndrome Other presenting signs or symptoms can include confusion, fatigue, palpitations, chest pain, shortness of breath, headache, and nausea. (wikipedia.org)
  • In tachycardia-bradycardia syndrome, medication-based management can treat atrial tachyarrhythmias. (wikipedia.org)
  • Sick sinus syndrome is the name given to a group of arrhythmias that occur because the normal pacemaker of the heart (the sinus node) does not work properly. (wellspan.org)
  • People with this syndrome can have slow arrhythmias or a combination of fast and slow arrhythmias. (wellspan.org)
  • Periods of fast arrhythmias (tachycardias), especially atrial fibrillation or atrial flutter, alternating with periods of very slow heart rates ("tachy-brady" syndrome). (wellspan.org)
  • In people with sick sinus syndrome, the SA node does not function normally. (medlineplus.gov)
  • People with sick sinus syndrome may also feel tired or weak. (kat1055.com)
  • What is the Prognosis for People with Sick Sinus Syndrome? (kat1055.com)
  • Most people with sick sinus syndrome have few or no symptoms. (noseplasticsurgery.in)
  • Once symptoms of sick sinus syndrome appear, they usually worsen with time. (medlineplus.gov)
  • These changes lead to abnormal heartbeats and the other symptoms of sick sinus syndrome. (medlineplus.gov)
  • What are the symptoms of sick sinus syndrome? (brighamandwomens.org)
  • While marked sinus bradycardia is seen on the preoperative electrocardiogram ( top image ), the postprocedure electrocardiogram demonstrates supraventricular tachycardia ( bottom image A ) that eventually transitions to asystole ( bottom image B ). (silverchair.com)
  • Common cardiac pharmacology such as beta-blockers, calcium channel blockers, digoxin, sympatholytic medication, and other antiarrhythmics can alter sinus node function to create an arrhythmia such as sick sinus syndrome. (wikipedia.org)
  • Sinus arrhythmia is normal. (stroke.org)
  • CASE PRESENTATION Sick sinus syndrome is an arrhythmia associated with reduced automaticity of the sinoatrial node or impaired sinoatrial node conduction. (bvsalud.org)
  • Developing sinus arrest, sinus node exit block, sinus bradycardia, atrioventricular block, and other types of abnormal rhythms are also common complications. (wikipedia.org)
  • None had a history of high-grade atrioventricular block or sick sinus syndrome. (lu.se)
  • Your health care professional can detect WPW Syndrome through an electrocardiogram (EKG or ECG). (stroke.org)
  • An electrocardiogram example of sinus bradycardia. (clevelandclinic.org)
  • Irregular depolarization of the sinus node, however, causes paroxysms of tachycardia (supraventricular tachycardia/atrial fibrillation) between episodes of bradycardia. (mhmedical.com)
  • The main symptom of sick sinus syndrome is an irregular heart rate. (kat1055.com)
  • Sinus arrest. (noseplasticsurgery.in)
  • Sinoatrial node depolarization is irregular or fails, resulting in bradycardia or sinus arrest. (mhmedical.com)
  • Sick sinus syndrome diagnosed after a sinus arrest during treatment for zygomatic fracture: a case report. (bvsalud.org)
  • Intraoperative sinus arrest is rarely seen during zygomatic fracture treatment . (bvsalud.org)
  • The patient was diagnosed with sick sinus syndrome based on repeated postoperative sinus arrest, which could have resulted in death if diagnosed late, making this case very significant to report . (bvsalud.org)
  • We report the case of a 67-year-old man diagnosed with the syndrome after a sinus arrest that occurred during a zygomatic fracture treatment . (bvsalud.org)
  • During the operation, sinus arrest was observed due to trigeminal vagal reflex , and heart rate was restarted by stopping the operation and chest compressions. (bvsalud.org)
  • After the surgery , the patient showed symptoms of dizziness and palpitations, and sinus arrest following atrial fibrillation and supraventricular tachycardia , which was diagnosed as sick sinus syndrome , and a pacemaker was implanted. (bvsalud.org)
  • However in patients with sick sinus syndrome, verapamil HCl may interfere with sinus node impulse generation and may induce sinus arrest or sinoatrial block. (drugs.com)
  • normal P waves are absent, giving the appearance of sinus arrest. (msdmanuals.com)
  • BACKGROUND: Intraoperative sinus arrest is rarely seen during zygomatic fracture treatment. (bvsalud.org)
  • Sick sinus syndrome (SSS) is a disease that affects the heart's natural pacemaker (the SA or sinoatrial node), located in the heart's upper right chamber (right atrium). (brighamandwomens.org)
  • The SA node (also known as the sinus node) is your heart's natural pacemaker and generates the electrical current that makes your heart muscle squeeze. (clevelandclinic.org)
  • Sick sinus syndrome is a type of bradycardia, a condition in which the heart beats too slowly. (kat1055.com)
  • Dr. Padmanabhan has experience treating conditions like Sinus Bradycardia, Rheumatic Aortic Valve Disorders and Mitral and Aortic Valve Disorder among other conditions at varying frequencies. (sharecare.com)
  • Periods of time when the sinus node does not fire at all (sinus pauses) and other areas of the heart take over and cause the heart to beat. (wellspan.org)
  • Less commonly, the AV junction develops abnormal automaticity and exceeds the sinus node rate at a time when the sinus rate would be normal (see image below). (medscape.com)
  • A particular variation in another gene, MYH6 , appears to increase the risk of developing sick sinus syndrome. (medlineplus.gov)
  • When the sinus node (also called the sinoatrial or SA node) doesn't produce its electrical signals properly, the heart rate slows down, pauses or speeds up. (stroke.org)
  • Other intrinsic causes include inherited ion channel dysfunctions, remodeling diseases such as heart failure and atrial fibrillation, infiltrative diseases such as sarcoidosis, amyloidosis, hemochromatosis, and connective tissue diseases, inflammatory etiology such as rheumatic fever, Chagas disease, and Lyme disease, as well as atherosclerotic and ischemic changes to the sinus node artery. (wikipedia.org)
  • Attempt to define etiology of the Sick Sinus Syndrome in the individual patient may be impossible. (mhmedical.com)
  • Junctional rhythms are common in patients with sick sinus syndrome or in patients who have significant bradycardia that allows the AV nodal region to determine the heart rate. (medscape.com)
  • One example of sick sinus syndrome is tachy-brady syndrome. (wellspan.org)
  • Both atrial fibrillation and sick sinus syndrome (a subset of which is also known as "tachy-brady" syndrome) are more common in elderly patients. (patientcareonline.com)
  • Animal and human experiments indicate that metoprolol slows the sinus rate and decreases AV nodal conduction. (nih.gov)
  • Sick sinus syndrome tends to cause the heartbeat to be too slow (bradycardia), although occasionally the heartbeat is too fast (tachycardia). (medlineplus.gov)
  • In a typical heartbeat, a tiny cluster of cells at the sinus node sends out electrical signals, called impulses. (mayoclinic.org)
  • Sick sinus syndrome can be caused by scarring near the sinus node that slows, disrupts or blocks heartbeat signals. (mayoclinic.org)
  • Sinus bradycardia tends to happen in adults, especially those over age 65, as your heartbeat tends to naturally slow down as you age. (clevelandclinic.org)
  • Case reports began appearing in the literature in the late 1930s and early 1940s, and the term Wolff-Parkinson-White (WPW) syndrome was coined in 1940. (rjmatthewsmd.com)
  • In consequence, there is an enrichment of 36 specific Mendelian genetic diseases such as congenital nephrotic syndrome, Finnish type (CNF) 8 in certain areas of Finland today that show mostly recessive inheritance. (nature.com)
  • CONCLUSION: This report showed a high prevalence of sick sinus syndrome in a clinical cohort of people with dementia with Lewy bodies. (lu.se)
  • Brugada syndrome (BrS) is a hereditary clinical-electrocardiographic arrhythmic entity with low worldwide prevalence. (bvsalud.org)
  • What are possible complications of sick sinus syndrome? (brighamandwomens.org)
  • What Complications Can Occur with Sick Sinus Syndrome? (kat1055.com)
  • Sick sinus syndrome can cause serious complications, such as fainting or sudden cardiac death. (kat1055.com)
  • The prognosis for sick sinus syndrome depends on the underlying cause and the severity of the condition. (kat1055.com)
  • There are no reports of maxillofacial trauma leading to a diagnosis of sick sinus syndrome . (bvsalud.org)
  • Noncompaction Cardiomyopathy, Sick Sinus Disease, and Aortic Dilatation: Too Much for a Single Diagnosis? (ucl.ac.uk)
  • Three participants (10.7%) received a diagnosis of sick sinus syndrome, of whom two received pacemaker implants to manage associated symptoms. (lu.se)
  • The National Institute for Health and Care Excellence's definition of post Covid-19 syndrome is: "Signs and symptoms that develop during or after an infection consistent with Covid-19, continue for more than 12 weeks and are not explained by an alternative diagnosis. (thesun.ie)
  • HCN4 mutations have been reported in association with sick sinus syndrome. (ucl.ac.uk)
  • Thus, we believe that this in-depth analytical study of the countless mutations attributed to BrS may constitute a real cornerstone that will help to better understand this intriguing syndrome. (bvsalud.org)
  • Age-related degenerative fibrosis of the sinus node is often identified as the most common intrinsic cause. (wikipedia.org)
  • The AV node (AVN) has intrinsic automaticity that allows it to initiate and depolarize the myocardium during periods of significant sinus bradycardia or complete heart block. (medscape.com)
  • Sick sinus syndrome affects men and women equally and can occur at any age. (brighamandwomens.org)
  • Sick sinus syndrome can occur at any age, but is more common in people aged 70 and over. (noseplasticsurgery.in)
  • If you have this syndrome, you may have symptoms such as palpitations and lightheadedness. (wellspan.org)
  • The syndrome may be acquired or congenital. (mhmedical.com)
  • Sinus bradycardia is less likely to occur in children (but still possible in rare cases) unless it happens because of a condition that a child has when they're born (congenital). (clevelandclinic.org)
  • In less than three decades since the discovery of Brugada syndrome, the concept of Mendelian heredity has come undone. (bvsalud.org)
  • The syndrome is caused by changes in the structure and function of certain cardiac ion channels and reduced expression of Connexin 43 (Cx43) in the Right Ventricle (RV), predominantly in the Right Ventricular Outflow Tract (VSVD), causing electromechanical abnormalities. (bvsalud.org)
  • Sick sinus syndrome accounts for 1 in 600 patients with heart disease who are over age 65. (medlineplus.gov)
  • The sinus node is the normal pacemaker of the heart. (kat1055.com)
  • The sinus node generates an electrical charge more slowly than normal. (noseplasticsurgery.in)
  • Electrolyte abnormalities such as hyperkalemia, hypokalemia, and hypocalcemia can also alter normal sinus node functioning. (wikipedia.org)
  • Rarely, the AVN develops enhanced automaticity and overtakes a "normal" sinus node. (medscape.com)
  • Sick sinus" refers to the sino-atrial (SA) node, which is an area of specialized cells in the heart that functions as a natural pacemaker. (medlineplus.gov)
  • One of the most common causes of sick sinus syndrome in children is trauma to the SA node, such as damage that occurs during heart surgery. (medlineplus.gov)
  • In older adults, sick sinus syndrome is often associated with age-related changes in the heart. (medlineplus.gov)
  • Prolonged periods of time when the heart rate is spontaneously very slow and does not increase as it should with activity (persistent sinus bradycardia). (wellspan.org)
  • Sick sinus syndrome is the inability of the natural pacemaker (sinus node) to generate a heart rate that matches the body's needs. (noseplasticsurgery.in)
  • The sinus node is an area of ​​specialized cells in the upper right ventricle of the heart. (noseplasticsurgery.in)
  • The heart may be involved in a number of systemic syndromes. (health.am)
  • The sinus node sets the pace of the heart. (mayoclinic.org)
  • In a typical heart, a tiny group of cells at the sinus node sends out an electrical signal. (mayoclinic.org)
  • Acquired causes include surgical trauma, fibrous, inflammatory, or degenerative infiltration of the sinus node and ischemia. (mhmedical.com)