Sinoatrial Block
Adams-Stokes Syndrome
A condition of fainting spells caused by heart block, often an atrioventricular block, that leads to BRADYCARDIA and drop in CARDIAC OUTPUT. When the cardiac output becomes too low, the patient faints (SYNCOPE). In some cases, the syncope attacks are transient and in others cases repetitive and persistent.
Sinoatrial Node
The small mass of modified cardiac muscle fibers located at the junction of the superior vena cava (VENA CAVA, SUPERIOR) and right atrium. Contraction impulses probably start in this node, spread over the atrium (HEART ATRIUM) and are then transmitted by the atrioventricular bundle (BUNDLE OF HIS) to the ventricle (HEART VENTRICLE).
Heart Block
Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
Tachycardia, Sinoatrial Nodal Reentry
Conduction disturbances and increased atrial vulnerability in Connexin40-deficient mice analyzed by transesophageal stimulation. (1/24)
BACKGROUND: Recently, it has been reported that connexin40 (Cx40) deficiency in targeted mouse mutants is associated with a prolongation of P-wave and QRS complex duration on surface electrograms. The specific effects of Cx40 deficiency on sinus node function, sinoatrial, and atrioventricular conduction properties as well as on atrial vulnerability have not yet been investigated systematically by electrophysiological analysis. METHODS AND RESULTS: Fifty-two mice (18 Cx40(+/+), 15 Cx40(+/-), and 19 Cx40(-/-) mice) were subjected to rapid atrial transesophageal stimulation after anesthesia with avertin. A significant prolongation of sinus node recovery time was noticed in Cx40(-/-) mice compared with Cx40(+/-) and Cx40(+/+) mice (287.8+/-109.0 vs 211.1+/-61.8 vs 204.4+/-60.9 ms; P<0.05). In addition, Wenckebach periodicity occurred at significantly longer atrial pacing cycle lengths in Cx40(-/-) mice than in Cx40(+/-) or Cx40(+/+) mice (93. 3+/-11.8 vs 83.9+/-9.7 vs 82.8+/-8.0 ms, P<0.05). Analysis of 27 Cx40(-/-) mice showed a significant increase in intra-atrial conduction time and atrioventricular conduction time compared with 52 Cx40(+/-) and 31 wild-type (Cx40(+/+)) mice. Furthermore, in Cx40(-/-) mice, atrial tachyarrhythmias could be induced frequently by atrial burst pacing, whereas no atrial arrhythmias were inducible in heterozygous or wild-type mice. CONCLUSIONS: This study demonstrates that Cx40 deficiency is associated with sinoatrial, intra-atrial, and atrioventricular conduction disturbances. In atrial myocardium of the mouse, Cx40 deficiency results in increased atrial vulnerability and might contribute to arrhythmogenesis. (+info)Development of sinus node disease in patients with AV block: implications for single lead VDD pacing. (2/24)
OBJECTIVE: To investigate the incidence of sinus node disease after pacemaker implantation for exclusive atrioventricular (AV) block. DESIGN: 441 patients were followed after VDD (n = 219) or DDD pacemaker (n = 222) implantation for AV block over a mean period of 37 months. Sinus node disease and atrial arrhythmias had been excluded by Holter monitoring and treadmill exercise preoperatively in 286 patients (group A). In 155 patients with complete AV block, a sinus rate above 70 beats/min was required for inclusion in the study (group B). Holter monitoring and treadmill exercise were performed two weeks, three months, and every six months after implantation. Sinus bradycardia below 40 beats/min, sinoatrial block, sinus arrest, or subnormal increase of heart rate during treadmill exercise were defined as sinus node dysfunction. RESULTS: Cumulative incidence of sinus node disease was 0.65% per year without differences between groups. Clinical indicators of sinus node dysfunction were sinus bradycardia below 40 beats/min in six patients (1.4%), intermittent sinoatrial block in two (0.5%), and chronotropic incompetence in five patients (1.1%). Only one of these patients (0.2%) was symptomatic. Cumulative incidence of atrial fibrillation was 2.0% per year, independent of the method used for the assessment of sinus node function and of the implanted device. CONCLUSIONS: In patients undergoing pacemaker implantation for isolated AV block, sinus node syndrome rarely occurs during follow up. Thus single lead VDD pacing can safely be performed in these patients. (+info)Atrio-sinus interaction demonstrated by blockade of the rapid delayed rectifier current. (3/24)
BACKGROUND: Proper pacemaking of the heart requires a specific organization of the sinoatrial (SA) node. The SA node drives the surrounding atrium but needs to be protected from its hyperpolarizing influence, which tends to suppress pacemaker activity. It has been suggested that the hyperpolarizing atrial influence is minimal at the site of the central nodal area. METHODS AND RESULTS: Atrio-sinus interaction was assessed by specific depolarization of the SA node by blocking the HERG-encoded rapid delayed rectifier current (I(K,r)) with the drug E-4031. In the SA node, E-4031 (1 micromol/L) changed action potential configuration drastically but never resulted in pacemaker arrest. In the atrium, E-4031 did not affect the membrane resting potential, thereby leaving the normal hyperpolarizing load on the SA node intact. When the SA node was sectioned into strips and subsequently separated from the atrium, spontaneous electrical activity of the strip containing the primary pacemaker ceased on I(K,r) blockade. When not separated from the atrium, I(K,r) blockade never resulted in pacemaker arrest. A similar effective atrio-sinus interaction was demonstrated in computer simulations. CONCLUSIONS: Our results demonstrate that the atrium provides an effective hyperpolarizing load on the central SA nodal area and is at least one of the controlling mechanisms for normal pacemaking function. The present study can be of help in understanding why patients with long-QT2 syndrome secondary to a mutation in HERG do not show sinus arrest. (+info)Comparative study of sinoatrial conduction time and sinus node recovery time. (4/24)
Atrial stimulation were performed in 5 normal patients (group A) and 4 patients with electrocardiographic evidence of sinoatrial disease (group B). The technique of premature atrial stimulation was used to calculate sinoatrial conduction time. Rapid atrial pacing was applied to measure maximum sinus node recovery time. In 4 cases both stimulation methods were repeated after intravenous administration of atropine Group A had a sinoatrial conduction time of 56 ms +/- 11 (SD) and a maximum sinus node recovery time of 1122 ms +/- 158. In 3 out of 4 patients with sinus node dysfunction a prolongation of sinoatrial conduction time could be demonstrated (145, 105, and 150 ms). In addition, one showed probable sinus node exit block after premature atrial stimulation. Sinus node recovery time was excessively prolonged in 2 (3880 and 3215 ms) and normal in the other 2 patients with sinoatrial disease (1330 and 1275 ms). Atropine leads to a decrease of sinoatrial conduction time. Results indicate that sinus node recovery time may not be a reliable indicator of sinus node automaticity if sinoatrial conduction is disturbed. The premature atrial stimulation technique makes it possible to study the pattern of sinoatrial conduction and to evaluate its reaction to therapeutic drugs. (+info)Sinus node dysfunction in acute myocardial infarction. (5/24)
The frequency, clinical course, and prognosis of sinus node dysfunction in 431 patients with acute myocardial infarction admitted to the coronary care unit were studied. Sinus node dysfunction occurred in 20 patients. In 13, the principal manifestation consisted of severe sinus bradycardia. In the remaining 7, periods of bradycardia alternating with episodes of supraventricular tachycardia were noted. Though several of the patients with sinus bradycardia required intravenous atropine or temporary pacing, normal sinus rhythm returned in virtually all during follow-up. The clinical course of patients with both bradycardia and tachycardia was less benign, during the acute phase and during follow-up; 5 of the 6 survivors required continued antiarrhythmic therapy or permanent pacing. The differences in the clinical course between these two groups of patients may reflect distinct underlying pathological changes. The findings in this study suggest that in contrast to sinus bradycardia, the occurrence of bradycardia-tachycardia syndrome during the acute phase of myocardial infarction may have important prognostic implications. (+info)Sinoatrial block complicating legionnaire's disease. (6/24)
A 59 year old woman presented with acute onset of fever, chills, diaphoresis, vague chest discomfort, and was found to be hypotensive and tachypnoeic. An electrocardiogram demonstrated sinoatrial block with a junctional rhythm between 50 and 80 beats/min. All cultures were negative and imaging studies unrevealing. Her urine tested positive for Legionella pneumophila antigen serotype 1 and she improved with antibiotic therapy. (+info)Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression. (7/24)
BACKGROUND: Homozygous mutant mice with a defect of klotho gene expression (kl/kl) show multiple age-related disorders and premature death from unknown causes. METHODS AND RESULTS: The kl/kl mice subjected to 20-hour restraint stress showed a high rate (20/30) of sudden death, which was associated with sinoatrial node dysfunction (conduction block or arrest). Heart rate and plasma norepinephrine of kl/kl mice, unlike those of wild-type (WT) mice, failed to increase during the stress. Intrinsic heart rate after pharmacological blockade of autonomic nerves in kl/kl mice was significantly lower than that in WT mice (380+/-33 versus 470+/-44 bpm; n=7). The sinus node recovery time after an overdrive pacing (600 bpm, 30 seconds) in kl/kl mice was significantly longer than in WT mice (392+/-37 versus 233+/-24 ms; n=6). In isolated sinoatrial node preparations, the positive chronotropic effect of isoproterenol was significantly less, whereas the negative chronotropic effect of acetylcholine was significantly greater in kl/kl than in WT mice. There was no degenerative structural change in the sinoatrial node of kl/kl mice. The precise localization of klotho was analyzed in newly prepared klotho-null mice with a reporter gene system (kl(-geo)). Homozygous kl(-geo) mice showed characteristic age-associated phenotypes that were almost identical to those of kl/kl mice. In the kl(-geo) mice, klotho expression was recognized exclusively in the sinoatrial node region in the heart in addition to parathyroid, kidney, and choroid plexus. CONCLUSIONS: In the heart, klotho is expressed solely at the sinoatrial node. klotho gene expression is essential for the sinoatrial node to function as a dependable pacemaker under conditions of stress. (+info)Quinine-induced arrhythmia in a patient with severe malaria. (8/24)
It was reported that there was a case of severe malaria patient with jaundice who presented with arrhythmia (premature ventricular contraction) while getting quinine infusion was reported. A man, 25 years old, was admitted to hospital with high fever, chill, vomiting, jaundice. The patient was fully conscious, blood pressure 120/80 mmHg, pulse rate 100 x/minute, regular. On admission, laboratory examination showed Plasmodium falciparum (++++), total bilirubin 8.25 mg/dL, conjugated bilirubin 4.36 mg/dL, unconjugated bilirubin 3.89 mg/dL, potassium 3.52 meq/L Patient was diagnosed as severe malaria with jaundice and got quinine infusion in dextrose 5% 500 mg/8 hour. On the second day the patient had vomitus, diarrhea, tinnitus, loss of hearing. After 30 hours of quinine infusion the patient felt palpitation and electrocardiography (ECG) recording showed premature ventricular contraction (PVC) > 5 x/minute, trigemini, constant type--sinoatrial block, positive U wave. He was treated with lidocaine 50 mg intravenously followed by infusion 1500 mg in dextrose 5%/24 hour and potassium aspartate tablet. Quinine infusion was discontinued and changed with sulfate quinine tablets. Three hours later the patient felt better, the frequency of PVC reduced to 4 - 5 x/minute and on the third day ECG was normal, potassium level was 3.34 meq/L. He was discharged on 7th day in good condition. Quinine, like quinidine, is a chincona alkaloid that has anti-arrhythmic property, although it also pro-arrhythmic that can cause various arrhythmias, including severe arrhythmia such as multiple PVC. Administration of parenteral quinine must be done carefully and with good observation because of its pro-arrhythmic effect, especially in older patients who have heart diseases or patients with electrolyte disorder (hypokalemia) which frequently occurs due to vomiting and or diarrhea in malaria cases. (+info)A Sinoatrial block is a cardiac conduction disorder characterized by the intermittent or persistent failure of impulse transmission from the sinoatrial node to the atrium, which can result in heart rate pauses and variable atrioventricular conduction ratios, often manifesting as sinus bradycardia, arterioventricular block or arrhythmias.
Sinoatrial block is a type of heart conduction disorder that affects the sinoatrial node, which is the natural pacemaker of the heart. In a sinoatrial block, the electrical impulses that originate in the sinoatrial node are delayed or blocked, resulting in a slower than normal heart rate or pauses between heartbeats.
A sinoatrial block can be classified as first-, second-, or third-degree, depending on the severity of the block. In a first-degree sinoatrial block, the electrical impulses are slowed but still conducted through to the atria. In a second-degree sinoatrial block, some of the electrical impulses are blocked, resulting in dropped beats or an irregular heart rhythm. In a third-degree sinoatrial block, also known as sinus node arrest, there is a complete failure of the sinoatrial node to generate impulses, resulting in a prolonged pause followed by a ventricular escape rhythm.
Sinoatrial blocks can be caused by various factors, including aging, heart disease, medication side effects, and electrolyte imbalances. In some cases, a sinoatrial block may not cause any symptoms and may only be detected during a routine electrocardiogram (ECG). However, in more severe cases, a sinoatrial block can lead to symptoms such as palpitations, dizziness, syncope (fainting), or shortness of breath. Treatment for a sinoatrial block depends on the underlying cause and may include medication adjustments, pacemaker implantation, or other interventions.
Adams-Stokes Syndrome is a disorder characterized by recurrent episodes of temporary loss of consciousness (syncope) due to transient cerebral hypoxia, often associated with bradyarrhythmias or asystole caused by underlying heart diseases such as sick sinus syndrome or AV block.
Adams-Stokes syndrome is a medical condition characterized by a series of episodes of sudden loss of consciousness (syncope) due to a significant decrease or temporary cessation of heart function (cardiac standstill or severe bradycardia). These episodes are often associated with convulsive movements and may be triggered by certain positions or activities that increase the obstruction to blood flow from the heart.
The syndrome is named after English physicians Robert Adams and William Stokes, who independently described the condition in the 19th century. It is most commonly caused by heart block or sick sinus syndrome, which are electrical conduction disorders of the heart. Other causes may include structural heart diseases, such as hypertrophic cardiomyopathy or coronary artery disease.
Treatment for Adams-Stokes syndrome typically involves addressing the underlying cause. In some cases, a pacemaker may be required to regulate the heart's electrical activity and prevent further episodes of syncope.
The sinoatrial node is the primary cardiac pacemaker, a small group of specialized cells located in the right atrium near the entrance of the superior vena cava, responsible for generating electrical impulses that initiate and regulate the heart's rhythmic contractions.
The sinoatrial (SA) node, also known as the sinus node, is the primary pacemaker of the heart. It is a small bundle of specialized cardiac conduction tissue located in the upper part of the right atrium, near the entrance of the superior vena cava. The SA node generates electrical impulses that initiate each heartbeat, causing the atria to contract and pump blood into the ventricles. This process is called sinus rhythm.
The SA node's electrical activity is regulated by the autonomic nervous system, which can adjust the heart rate in response to changes in the body's needs, such as during exercise or rest. The SA node's rate of firing determines the heart rate, with a normal resting heart rate ranging from 60 to 100 beats per minute.
If the SA node fails to function properly or its electrical impulses are blocked, other secondary pacemakers in the heart may take over, resulting in abnormal heart rhythms called arrhythmias.
'Heart block' is a cardiac conduction disorder characterized by the interruption or delay of electrical impulse transmission from the atria to the ventricles through the atrioventricular node or the His-Purkinje system.
Heart block is a cardiac condition characterized by the interruption of electrical impulse transmission from the atria (the upper chambers of the heart) to the ventricles (the lower chambers of the heart). This disruption can lead to abnormal heart rhythms, including bradycardia (a slower-than-normal heart rate), and in severe cases, can cause the heart to stop beating altogether. Heart block is typically caused by damage to the heart's electrical conduction system due to various factors such as aging, heart disease, or certain medications.
There are three types of heart block: first-degree, second-degree, and third-degree (also known as complete heart block). Each type has distinct electrocardiogram (ECG) findings and symptoms. Treatment for heart block depends on the severity of the condition and may include monitoring, medication, or implantation of a pacemaker to regulate the heart's electrical activity.
Tachycardia, Sinoatrial Nodal Reentry is defined as an abnormally rapid heart rate, typically over 100 beats per minute, caused by a reentrant circuit within or near the sinoatrial node, resulting in excessive discharge of automatic impulses from the node.
Tachycardia is a heart rate that is faster than normal. In sinoatrial nodal reentry tachycardia (SANRT), the abnormally fast heart rhythm originates in the sinoatrial node, which is the natural pacemaker of the heart. This type of tachycardia occurs due to a reentry circuit within the sinoatrial node, where an electrical impulse travels in a circular pattern and repeatedly stimulates the node to fire off abnormal rapid heartbeats. SANRT is typically characterized by a heart rate of over 100 beats per minute, palpitations, lightheadedness, or occasionally chest discomfort. It is usually a benign condition but can cause symptoms that affect quality of life. In some cases, treatment may be required to prevent recurrences and manage symptoms.
Sinoatrial block
A sinoatrial block (also spelled sinuatrial block) is a disorder in the normal rhythm of the heart, known as a heart block, ... Sinoatrial blocks are typically well tolerated. They are not as serious as an AV block and most often do not require treatment ... Conduction across the SA node is normal until the time of the pause when it is blocked. A third degree sinoatrial block looks ... In a first degree sinoatrial block, there is a lag between the time that the SA node fires and actual depolarization of the ...
H. H. R. Samarasinghe
Permanent neurological deficits complicating sino-atrial block". Br Heart J. 35 (5): 503-6. doi:10.1136/hrt.35.5.503. PMC ...
Sinoatrial arrest
This condition is sometimes confused with sinoatrial block, a condition in which the pacing impulse is generated, but fails to ... Sinoatrial arrest is a medical condition wherein the sinoatrial node of the heart transiently ceases to generate the electrical ... If a pacemaker other than the sinoatrial node is pacing the heart, this condition is known as an escape rhythm. If no other ... as a brief period of irregular length with no electrical activity before either the sinoatrial node resumes normal pacing, or ...
Cerberin
... second-degree sinoatrial block and nodal rhythm are also described. In the case of digitalis administration, ST depression or T ... Cerberin is able to bind to the extracellular part of the Na+/K+-ATPase pump and can block the dephosphorylation step. Due to ... Newman, R. A.; Yang, P.; Pawlus, A. D.; Block, K. I. (2008). "Cardiac Glycosides as Novel Cancer Therapeutic Agents". Molecular ...
Muscarinic antagonist
It causes tachycardia by blocking vagal effects on the sinoatrial node. Acetylcholine hyperpolarizes the sinoatrial node; this ... A muscarinic receptor antagonist (MRA) is a type of anticholinergic agent that blocks the activity of the muscarinic ... One method of balancing the neurotransmitters is through blocking central cholinergic activity using muscarinic receptor ...
Dario DiFrancesco
Bucchi, Annalisa; Baruscotti, Mirko; DiFrancesco, Dario (2002-06-10). "Current-dependent Block of Rabbit Sino-Atrial Node If ... These results showed that the mechanism of pacemaker generation in Purkinje fibres and in sinoatrial node cells was the same, ... DiFrancesco, D. (December 4-10, 1986). "Characterization of single pacemaker channels in cardiac sino-atrial node cells". ... in cells isolated from the rabbit sino-atrial node". The Journal of Physiology. 377: 61-88. doi:10.1113/jphysiol.1986.sp016177 ...
List of dog diseases
It is characterized by sinoatrial node dysfunction and may include atrioventricular node disease and bundle branch block. ... Electrocardiogram findings include sinus bradycardia, sinus arrest, sinoatrial heart block, and atrial tachycardia. The major ... Chalazion* is a granuloma that forms in the eyelid due to blocked secretions from the meibomian gland. Inflammation of the ... Congenital vertebral anomalies, including butterfly, block, and transitional vertebrae, and hemivertebrae, are a collection of ...
Bradycardia
... "exit block"). Second-degree sinoatrial blocks can be detected only by use of a 12-lead ECG. It is difficult and sometimes ... AV conduction disturbances (AV block; primary AV block, secondary type I AV block, secondary type II AV block, tertiary AV ... The third, sick sinus syndrome, covers conditions that include severe sinus bradycardia, sinoatrial block, sinus arrest, and ... The clinical relevance pertaining to AV blocks is greater than that of SA blocks. Beta blocker medicines also can slow the ...
Arrhythmia
... and third-degree blocks also can occur at the level of the sinoatrial junction. This is referred to as sinoatrial block ... or by blocking of the electrical impulse on its way from the atria to the ventricles (AV block or heart block). Heart block ... also known as Mobitz I or Wenckebach Type 2 Second degree heart block, also known as Mobitz II Third-degree heart block, also ... which manifests as PR prolongation Second-degree heart block Type 1 Second degree heart block, ...
Syncope (medicine)
... is usually caused by sinoatrial node dysfunction or block or atrioventricular block. Blockages in major vessels or within the ... Adams-Stokes syndrome is a cardiac syncope that occurs with seizures caused by complete or incomplete heart block. Symptoms ... Bradycardia can be caused by heart blocks. Tachycardias include SVT (supraventricular tachycardia) and VT (ventricular ...
Digoxin toxicity
... sinoatrial block and AV block. In individuals with suspected digoxin toxicity, a serum digoxin concentration, serum potassium ...
Atrioventricular block
Normally, the sinoatrial node (SA node) produces an electrical signal to control the heart rate. The signal travels from the SA ... Atrioventricular block (AV block) is a type of heart block that occurs when the electrical signal traveling from the atria, or ... Third-degree AV block is the most severe of the AV blocks. Persons with third-degree AV block need emergency treatment ... First-degree AV block and Mobitz I second-degree block are often thought to be just normal, benign, conditions in people, and ...
List of MeSH codes (C23)
... bundle-branch block MeSH C23.550.073.425.780 - sinoatrial block MeSH C23.550.073.670 - parasystole MeSH C23.550.073.845 - ... sinoatrial nodal reentry MeSH C23.550.073.845.880.845 - tachycardia, sinus MeSH C23.550.073.845.940 - tachycardia, ventricular ... heart block MeSH C23.550.073.425.025 - adams-stokes syndrome MeSH C23.550.073.425.100 - ...
Sinus node dysfunction
... can also present with sudden sinus arrest with or without junctional escape, sinoatrial block, prolonged ... Developing sinus arrest, sinus node exit block, sinus bradycardia, atrioventricular block, and other types of abnormal rhythms ... Dual chamber pacemakers are preferred due to the possibility of developing atrioventricular block as well as long term cost- ... "Dual-chamber pacemakers for treating symptomatic bradycardia due to sick sinus syndrome without atrioventricular block: a ...
Lidocaine
Severe sinoatrial block (without pacemaker) Serious adverse drug reaction to lidocaine or amide local anesthetics ... Blocking sodium channels in the conduction system, as well as the muscle cells of the heart, raises the depolarization ... This means it works by blocking sodium channels and thus decreasing the rate of contractions of the heart. When injected near ... It can be administered in multiple ways, most often as a nerve block or infiltration, depending on the type of treatment ...
Phenytoin
... sinoatrial block, second- or third-degree atrioventricular block, Stokes-Adams syndrome, or hypersensitivity to phenytoin, ... This blocks sustained high frequency repetitive firing of action potentials. This is accomplished by reducing the amplitude of ... Because it takes time for the bound drug to dissassociate from the inactive channel, there is a time-dependent block of the ... use-dependent and time-dependent block of sodium-dependent action potentials. The primary site of action appears to be the ...
Heart block
"Sinoatrial block"), AV node ("AV block" or AVB), and at or below the bundle of His ("Intra-Hisian" or "Infra-Hisian block" ... Types of infra-Hisian block include: Type 2 second degree heart block (Mobitz II) -a type of AV block due to a block within or ... Therefore, most of the important heart blocks are AV nodal blocks and infra-Hisian blocks. SA blocks are usually of lesser ... block Left posterior fascicular block Right bundle branch block Left bundle branch block Of these types of infra-Hisian block, ...
List of MeSH codes (C14)
... bundle-branch block MeSH C14.280.067.558.750 - sinoatrial block MeSH C14.280.067.565 - long QT syndrome MeSH C14.280.067.565. ... sinoatrial nodal reentry MeSH C14.280.067.845.880.845 - tachycardia, sinus MeSH C14.280.067.845.940 - tachycardia, ventricular ... heart block MeSH C14.280.067.558.137 - Adams-Stokes syndrome MeSH C14.280.067.558.323 - ...
Myocardial infarction complications
... and ischemia in the electrical conduction system of the heart may cause a complete heart block (when the impulse from the ... sinoatrial node, the normal cardiac pacemaker, does not reach the heart chambers). As a reaction to the damage of the heart ...
Bundle branch block
The heart's electrical activity begins in the sinoatrial node (the heart's natural pacemaker), which is situated on the upper ... Cardiac pacemaker Heart block First degree AV block Second degree AV block Third degree AV block Cecil Textbook of Medicine. W. ... block with either left anterior fascicular block or left posterior fascicular block together with a first degree AV block. ... Bifascicular block. This is a combination of right bundle branch block (RBBB) and either left anterior fascicular block (LAFB) ...
Sinoatrial node
If the SA node does not function or the impulse generated in the SA node is blocked before it travels down the electrical ... The sinoatrial node (also known as the sinuatrial node, SA node or sinus node) is an oval shaped region of special cardiac ... The sinoatrial node receives its blood supply from the sinoatrial nodal artery. This blood supply, however, can differ hugely ... "Human Sinoatrial Node Structure: 3D Microanatomy of Sinoatrial Conduction Pathways". Progress in Biophysics and Molecular ...
Electrocardiography
Aberration Sinoatrial block: first, second, and third-degree AV node First-degree AV block Second-degree AV block (Mobitz [ ... Left posterior fascicular block (LPFB) Bifascicular block (LAFB plus LPFB) Trifascicular block (LAFP plus FPFB plus RBBB) QT ... Wenckebach] I and II) Third-degree AV block or complete AV block Right bundle Incomplete right bundle branch block (IRBBB) ... Left bundle Incomplete left bundle branch block (ILBBB) Complete left bundle branch block (LBBB) Left anterior fascicular block ...
Tachycardia-dependent bundle branch block
... right bundle branch block or left bundle branch block.[citation needed] In a healthy heart, specialized cells in the sinoatrial ... This is referred to as a bundle branch block and is seen clinically as rate-dependent bundle branch block, ... A tachycardia-dependent bundle branch block is a defect in the conduction system of the heart, and is distinct from typical ... "Implications of Left Bundle Branch Block in Patient Treatment", Am J Cardiol 2013;111:291-300. Shlipak M. G. et al. "Treatment ...
Congenital heart block
Due to the block in the atrioventricular node, less electric signals move from the sinoatrial node to the bundle of his and its ... The congenital heart block (CHB) is the heart block that is diagnosed in fetus (in utero) or within the first 28 days after ... The atrioventricular block can be first degree or much more severe like a complete atrioventricular block (third degree). In ... The result of CHB can be first, second, or third-degree (complete) atrioventricular block (a block in the atrioventricular node ...
Third-degree atrioventricular block
AV block) is a medical condition in which the electrical impulse generated in the sinoatrial node (SA node) in the atrium of ... This may be preceded by first-degree AV block, second-degree AV block, bundle branch block, or bifascicular block. In addition ... Atrioventricular block First-degree AV block Second-degree AV block "ECG Conduction Abnormalities". Retrieved 2009-01-07. " ... Mobitz Type 2 AV block is another indication for pacing. As with other forms of heart block, secondary prevention may also ...
Right bundle branch block
... sinoatrial node, atria or atrioventricular node) to activate the conduction system at the correct point. The QRS duration must ... RBBB with associated first degree AV block RBBB with associated tachycardia RBBB Intraventricular block Bundle branch block ... A right bundle branch block (RBBB) is a heart block in the right bundle branch of the electrical conduction system. During a ... "Right Bundle Branch Block". Symptoma. Retrieved 2015-08-13. Harkness WT, Hicks M (2022). "Right Bundle Branch Block". ...
Karel Frederik Wenckebach
A similar phenomenon can also occur in the sinoatrial node where it gives rise to type I second degree SA block, and this is ... The condition was referred to as a "second degree AV block" and later named the "Wenckebach phenomenon" and reclassified as ... Wenckebach is credited for describing the median bundle of the heart's conductive system that connects the sinoatrial node to ... Karel Wenckebach: the story behind the block". Resuscitation. Ireland. 79 (2): 189-92. doi:10.1016/j.resuscitation.2008.05.015 ...
Junctional rhythm
... the sinoatrial node does not control the heart's rhythm - this can happen in the case of a block in conduction somewhere along ... Under normal conditions, the heart's sinoatrial node(SA node) determines the rate by which the organ beats - in other words, it ... is the heart's "pacemaker". The electrical activity of sinus rhythm originates in the sinoatrial node and depolarizes the atria ...
Ventricular escape beat
... or by atrioventricular block (especially third degree AV block). Normally, the pacemaker cells of the sinoatrial node discharge ... This phenomenon can be caused by the sinoatrial node (SA node) failing to initiate a beat, by a failure of the conductivity ... Third degree AV block can be treated with Cilostazol which acts to increase Ventricular escape rate Ouabain infusion decreases ... normally initiated by the heart's sinoatrial node (SA node), transmitted to the atrioventricular node (AV node), and then ...
List of ICD-9 codes 390-459: diseases of the circulatory system
Wenckebach's 426.3 Bundle branch block, left 426.4 Bundle branch block, right 426.6 Sinoatrial heart block 426.7 ... third degree 426.11 Atrioventricular block, first degree 426.12 Atrioventricular block, Mobitz II 426.13 Atrioventricular block ... diseases classified elsewhere 425.9 Secondary cardiomyopathy unspecified 426 Conduction disorders 426.0 Atrioventricular block ...
Sinoatrial block - Wikipedia
A sinoatrial block (also spelled sinuatrial block) is a disorder in the normal rhythm of the heart, known as a heart block, ... Sinoatrial blocks are typically well tolerated. They are not as serious as an AV block and most often do not require treatment ... Conduction across the SA node is normal until the time of the pause when it is blocked. A third degree sinoatrial block looks ... In a first degree sinoatrial block, there is a lag between the time that the SA node fires and actual depolarization of the ...
Sinoatrial Block | Profiles RNS
"Sinoatrial Block" by people in this website by year, and whether "Sinoatrial Block" was a major or minor topic of these ... "Sinoatrial Block" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Below are the most recent publications written about "Sinoatrial Block" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Sinoatrial Block". ...
Acyclovir and Sinoatrial Block - DrugCite
DailyMed - REGADENOSON injection
Sinoatrial and Atrioventricular Nodal Block [see Warnings and Precautions (5.2)]. •. Atrial Fibrillation/Atrial Flutter [see ... AV block (2:1 AV block, AV Mobitz I, AV Mobitz II, complete heart block); sinus arrest , 3 seconds in duration ... 5.2 Sinoatrial and Atrioventricular Nodal Block 5.3 Atrial Fibrillation/Atrial Flutter 5.4 Hypersensitivity, Including ... 5.2 Sinoatrial and Atrioventricular Nodal Block Adenosine receptor agonists, including regadenoson, can depress the SA and AV ...
Syncope Differential Diagnoses
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Chardonna-2 - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
Donnatal - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
Protuss Tablet - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
LANOXIN - Drug Information from Guideline Central
5.2 Sinus Bradycardia and Sino-atrial Block. LANOXIN may cause severe sinus bradycardia or sinoatrial block particularly in ... Risk of advanced or complete heart block in patients with sinus node disease and AV block. (5.2) ... or third-degree heart block (including asystole); atrial tachycardia with block; AV dissociation; accelerated junctional (nodal ... Neuromuscular Blocking Agents Succinylcholine. May cause sudden extrusion of potassium from muscle cells causing arrhythmias in ...
LF:aVLVL9X65c Internal medicine part 5 - Course Information
DailyMed - DONEPEZIL HYDROCHLORIDE tablet
... inhibitors may have vagotonic effects on the sinoatrial and atrioventricular nodes manifesting as bradycardia or heart block ( ... This effect may manifest as bradycardia or heart block in patients both with and without known underlying cardiac conduction ... A synergistic effect may be expected with concomitant administration of succinylcholine, similar neuromuscular blocking agents ... Because of their pharmacological action, cholinesterase inhibitors may have vagotonic effects on the sinoatrial and ...
Pharmacologic Approach to Sinoatrial Node Dysfunction - PubMed
Sino-atrial node dysfunction (SND) and sick sinoatrial (sick sinus) syndrome are caused by the hearts inability to generate a ... normal sinoatrial node action potential. In clinical practice, SND is generally considered an age-re … ... The spontaneous activity of the sinoatrial node initiates the heartbeat. ... Left) Typical tracing of ECG in Cav1.3−/− mice that present with sinoatrial bradycardia and atrioventricular block. (Center) ...
Overt and Latent Cardiac Effects of Ozone Inhalation in Rats: Evidence for Autonomic Modulation and Increased Myocardial...
... sinoatrial block, and atrioventricular block, accompanied by concurrent increases in several HR variability parameters that ... sinoatrial blocks (SABs), atrioventricular blocks (AVBs), or ventricular tachycardia. Arrhythmias were quantified and totaled ... SAB in humans is believed to be caused by a block of conduction within the sinoatrial junction while the sinus node itself ... 1991). The exact sites of the blocks produced in the present study are not known and could have been obtained with only ...
Fast Five Quiz: Syncope
Persistent sinus bradycardia (, 40 beats/min) or repetitive sinoatrial block or sinus pauses , 3 sec in awake state and in ... Mobitz I second-degree AV block and first-degree AV block with markedly prolonged PR interval ... Bundle branch block, intraventricular conduction disturbance, ventricular hypertrophy, or Q waves consistent with ischemic ...
Sinus Node Dysfunction - Cardiovascular Disorders - MSD Manual Professional Edition
Sinoatrial (SA) exit block. Sinus node dysfunction affects mainly older patients, especially those with another cardiac ... In type I second-degree SA (SA Wenckebach) block, impulse exit conduction slows before blocking, seen on the ECG as a P-P ... In type II second-degree SA block, impulse exit conduction is blocked without slowing beforehand, producing a pause that is a ... In third-degree SA block, impulse exit conduction is blocked; normal P waves are absent, giving the appearance of sinus arrest. ...
Adrien Barton</dc...
first degree sinoatrial block (disease). third degree sinoatrial block (disease). impaired sinoatrial node. heart block ( ... sinoatrial block (disease). Wenckebach block. Mobitz I second degree sinoatrial block (disease). sinus exit block. Mobitz II ... Mobitz II second degree sinoatrial block (process). first degree sinoatrial block (process). third degree sinoatrial block ( ... left posterior fascicular block (disease). infra-hisian block (disease). left bundle branch block (disease). A heart conduction ...
Epicardial Versus Endocardial Pacing in Paediatric Patients with Atrioventricular Block or Sinus Node Dysfunction: A Systematic...
... sinoatrial block.". Data Synthesis and Analysis. Rates of events have been recorded for both intervention (EPI children with ... The term "atrioventricular block" in this study refers to any degree of congenital or acquired heart block (1st, 2nd, or 3rd) ... M. Yokoyama, M. Sekiguchi, and M. Hori, "A 4-year survival rate after cardiac pacing in A-V block in the heart institute of ... Mertens L, Friedberg MK (2009) Selecting pacing sites in children with complete heart block: is it time to avoid the right ...
Cardizem LA Side Effects: Common, Severe, Long Term
... sinoatrial block, sinus node dysfunction, sinus pause/arrest, vasculitis, ventricular arrhythmia, ventricular fibrillation, ... block (first/second/third degree), bradycardia, bundle branch block, ECG abnormality, edema, extrasystole/ventricular ... First degree AV block and sinus bradycardia occurred more frequently with higher doses.[Ref] ...
CDC/NIH Web Information Database|Home|PHGKB
Chagas disease and focus on syncope in chronic chagasic cardiomyopathy
... sinoatrial block and sinus pause, and less frequently, bradycardia-tachycardia syndrome, probably due to autonomic denervation ... mostly in the infra-His location and frequently associated with right bundle branch block (7). These AV blocks were detected in ... The most common morphology of SVT is right bundle branch block (Fig. 3). Another site of origin of SVT is the right ventricle, ... In CM5 lead, there is a period of second-degree atrioventricular block Mobitz I. Patient underwent implantation of dual chamber ...
Spanish Pacemaker Registry. 17th Official Report of the Section on Cardiac Pacing of the Spanish Society of Cardiology (2019) |...
... sinus arrhythmia/sinoatrial block (2.4%), and chronotropic incompetence (0.1%). The SSS subtype was unspecified in 2.5% of ... Bundle branch block was slightly more common in men (6.7% vs 5.2%). Slow AF and blocked AF constituted 19.2% of the indications ... AVB, atrioventricular block; DDD/R, sequential pacing with 2 leads; IVCD, intraventricular conduction defect; SSS, sick sinus ... Trends in pacing modes in atrioventricular block from 2010 to 2019. DDD/R, sequential pacing with 2 leads; VDD/R, single-lead ...
Tiam1 Mouse Gene Details | T cell lymphoma invasion and metastasis 1 | International Mouse Phenotyping Consortium
Cognex (Tacrine) - Warnings and Precautions
Muscle Blood Flow Regulation | DrBeen
![Webinar] Using Dormosedan Gel To Sedate Uncooperative Horses](data:image/png;base64,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)
Webinar] Using Dormosedan Gel To Sedate Uncooperative Horses
Code System Concept
Estudo prospectivo das repercussões de baixas doses de remifentanil na função sinoatrial e na condução e refratariedade cardíaca
Patients with disorders of the sinoatrial node and those with severe cardiac blocks were excluded. In the laboratory of ... Houve aumento do intervalo átrio-His (p = 0,006) e do tempo de recuperação do nódulo sinoatrial (p = 0,0004), do período ... The atrium-His interval (p = 0.006), recovery time of the sinoatrial node (p = 0.0004), refractory period of the right atrium ( ... Foram excluídos os pacientes com doença do nódulo sinoatrial e os portadores de bloqueios cardíacos graves. No laboratório de ...