Smilacaceae
Neuroprotective effect of oxyresveratrol from smilacis chinae rhizome on amyloid Beta protein (25-35)-induced neurotoxicity in cultured rat cortical neurons. (1/2)
We previously reported that Smilacis chinae rhizome inhibits amyloid beta protein (25-35) (Abeta (25-35))-induced neurotoxicity in cultured rat cortical neurons. The present study evaluated the neuroprotective effect of oxyresveratrol isolated from Smilacis chinae rhizome against Abeta (25-35)-induced neurotoxicity on cultured rat cortical neurons. Oxyresveratrol over the concentration range of 1-10 microM significantly inhibited 10 microM Abeta (25-35)-induced neuronal cell death, which was measured by a 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide (MTT) assay and Hoechst 33342 staining. Oxyresveratrol (10 microM) inhibited 10 microM Abeta (25-35)-induced elevation of cytosolic calcium concentration ([Ca2+]c), which was measured by a fluorescent dye, Fluo-4 AM. Oxyresveratrol (1, 10 microM) also inhibited glutamate release into medium and reactive oxygen species (ROS) generation induced by 10 microM Abeta (25-35). These results suggest that oxyresveratrol prevents Abeta (25-35)-induced neuronal cell damage by interfering with the increase of [Ca2+]c, and then by inhibiting glutamate release and ROS generation. Furthermore, these effects of oxyresveratrol may be associated with the neuroprotective effect of Smilacis chinae rhizome. (+info)Chromosome diversity and evolution in Liliaceae. (2/2)
(+info)Smilacaceae is not a medical term, but a botanical term referring to a family of flowering plants known as the greenbriar family. The plants in this family are primarily found in tropical and subtropical regions around the world. Some members of Smilacaceae have been used in traditional medicine in various cultures, although more research is needed to confirm their effectiveness and safety.
If you're looking for a medical definition related to greenbriar or Smilacaceae plants, I would need more context to provide an accurate answer.
"Smilax" is a genus of flowering plants, also known as greenbriars. While "Smilax" itself is not a medical term, some species of this plant have been used in traditional medicine. For instance, the roots and rhizomes of Smilax aristolochiifolia (Mexican sarsaparilla) and Smilax ornata (Jamaican sarsaparilla) have been used in traditional herbal remedies for various health conditions, including skin diseases, rheumatism, and sexual impotence. However, it's important to note that the scientific evidence supporting these uses is generally weak, and these remedies may carry risks, such as allergic reactions or contamination with harmful substances. Always consult a healthcare provider before starting any new treatment.