A systemic non-inflammatory arteriopathy primarily of middle-aged females characterized by the association of livedo reticularis, multiple thrombotic CEREBRAL INFARCTION; CORONARY DISEASE, and HYPERTENSION. Elevation of antiphospholipid antibody titers (see also ANTIPHOSPHOLIPID SYNDROME), cardiac valvulopathy, ISCHEMIC ATTACK, TRANSIENT; SEIZURES; DEMENTIA; and chronic ischemia of the extremities may also occur. Pathologic examination of affected arteries reveals non-inflammatory adventitial fibrosis, thrombosis, and changes in the media. (From Jablonski, Dictionary of Syndromes & Eponymic Diseases, 2d ed; Adams et al., Principles of Neurology, 6th ed, p861; Arch Neurol 1997 Jan;54(1):53-60)
Skin diseases affecting or involving the cutaneous blood vessels and generally manifested as inflammation, swelling, erythema, or necrosis in the affected area.
A characteristic symptom complex.

The natural course of Sneddon syndrome: clinical and magnetic resonance imaging findings in a prospective six year observation study. (1/10)

Sneddon syndrome (SS) is increasingly recognised as a cause of ischaemic stroke in young adults. As the natural course of SS is not well defined, the authors performed a prospective six year clinical and neuroradiological follow up study. Thirteen patients with definite diagnosis of SS (livedo racemosa, characteristic skin biopsy, and history of stroke) entered a follow up programme that consisted of clinical examinations, two magnetic resonance imaging (MRI) investigations, and a comprehensive laboratory follow up protocol. The most frequent clinical findings during follow up had been headache (62%) and vertigo (54%). Seven patients (54%) suffered from transient ischaemic attacks, however, completed stroke has not been obtained during follow up. Progression of white matter lesions detected in MRI were present in 10 of 13 patients. Laboratory follow up protocol revealed transient antiphospholipid antibodies in two subjects. This prospective six year follow up study suggests a low incidence of territorial stroke but outlines progressive leucencephalopathy in patients with SS.  (+info)

Protein Z deficiency in antiphospholipid-negative Sneddon's syndrome. (2/10)

BACKGROUND: Sneddon's syndrome is characterized by the association of ischemic cerebrovascular events and widespread livedo racemosa. The pathophysiology of Sneddon's syndrome remains elusive, but various prothrombotic abnormalities have been previously reported in this setting. Low levels of protein Z, a downregulator of coagulation, have been recently linked to an increased risk of arterial thrombosis. The purpose of this study was to investigate the levels of protein Z in a series of Sneddon's syndrome patients without circulating antiphospholipid antibodies in comparison with an age- and sex-matched control population. METHODS: Twenty-six patients and 78 healthy controls had determination of their protein Z blood levels by an enzyme-linked immunoassay test. Patients' thrombotic and vascular risk factors, including tobacco smoking, arterial hypertension, oral contraceptive agents, dyslipidemia, factor V Leiden, and factor II mutation were recorded. RESULTS: Protein Z plasma levels were significantly lower in patients (mean 1.47 mg/L) than in controls (mean 1.93 mg/L) (P=0.02). Prevalence of protein Z deficiency (level <1 mg/L) was significantly higher (P=0.001) among patients (31%) than among controls (3.8%). Factor V Leiden and heavy smoking were observed in 4 and 7 patients, respectively. CONCLUSIONS: Sneddon's syndrome could be viewed as the peculiar clinical expression of various and sometimes associated coagulation abnormalities. Low levels of protein Z may account, at least partly, for the thrombotic events observed in Sneddon's syndrome and shed a new light on its pathophysiology. Clinical implications for protein Z deficiency in this setting deserve further investigations.  (+info)

Sneddon's syndrome: clinical and laboratory analysis of 10 cases. (3/10)

Sneddon's syndrome is characterized by livedo reticularis and cerebrovascular lesions. We report the cases of women (mean age, 36.2 +/- 8.1 years) diagnosed with Sneddon's syndrome based on the presence of livedo reticularis and characteristic cerebrovascular findings. Seven of these patients had cerebral infarcts on cranial computed tomography scan. Antiphospholipid antibodies were positive in 6 of these cases. Three cases had abnormal levels of antithrombin III. Analyses of chromosome 6 revealed no abnormalities. In 3 of the cases, investigation of the pedigrees revealed autosomal dominant traits. Two cases had epilepsy, and 3 had migraine. One case with migraine also had myasthenia gravis. In addition, we detected inferior altudinal hemianopia in 2 cases, cognitive functional disorder in 3 and depression in 2. Based on these findings, the entire vascular, haematologic, neurologic, and dermatologic systems should be evaluated in patients diagnosed with Sneddon's syndrome.  (+info)

Clinical, neurovascular and neuropathological features in Sneddon's syndrome. (4/10)

Sneddon's syndrome (SS) is characterized by ischemic cerebrovascular episodes and livedo reticularis. It is more common in young women and can also be associated with valvulopathy, a history of spontaneous abortion, renal involvement and vascular dementia. We describe three cases of young women with this disease. The patients had repeated ischemic cerebral episodes, livedo reticularis and thrombocytopenia. CT and MRI showed strokes and cerebral atrophy. Autopsy in one of the patients revealed cerebral infarctions. Anticardiolipin antibodies were detected in two patients. Antiphospholipid antibodies may be found in some patients with ischemic cerebrovascular events and livedo reticularis. SS may thus be associated with antiphospholipid syndrome. We described three new cases of SS and discuss the pathophysiology of this disease.  (+info)

Sneddon's syndrome presenting with severe disabling bilateral headache. (5/10)

 (+info)

Seizures in primary antiphospholipid syndrome: the relevance of smoking to stroke. (6/10)

 (+info)

Sneddon syndrome associated with Protein S deficiency. (7/10)

 (+info)

Sneddon's syndrome: case report and review of its relationship with antiphospholipid syndrome. (8/10)

 (+info)

Sneddon syndrome is a rare medical condition characterized by the concurrence of livedo reticularis (a purplish, net-like discoloration of the skin) and recurrent strokes or transient ischemic attacks (TIAs). It primarily affects young to middle-aged women. The exact cause of Sneddon syndrome remains unknown, but it's thought to be an autoimmune disorder with potential involvement of the coagulation system.

The main diagnostic criteria for Sneddon syndrome are:

1. Livedo reticularis (fixed, persistent form)
2. One or more cerebrovascular events (strokes or TIAs)

Additional features may include cognitive impairment, migraine-like headaches, seizures, and other neurological symptoms. Diagnosis is often challenging due to its rarity and the need to exclude other conditions that can present with similar symptoms. Treatment typically involves anticoagulation therapy, antiplatelet agents, or immunosuppressive medications to manage symptoms and prevent further cerebrovascular events.

Vascular skin diseases are a group of medical conditions that affect the blood vessels in the skin. These disorders can be caused by problems with the structure or function of the blood vessels, which can lead to various symptoms such as redness, discoloration, pain, itching, and ulcerations. Some examples of vascular skin diseases include:

1. Rosacea: a chronic skin condition that causes redness, flushing, and visible blood vessels in the face.
2. Eczema: a group of inflammatory skin conditions that can cause redness, itching, and dryness. Some types of eczema, such as varicose eczema, are associated with problems with the veins.
3. Psoriasis: an autoimmune condition that causes red, scaly patches on the skin. Some people with psoriasis may also develop psoriatic arthritis, which can affect the blood vessels in the skin and joints.
4. Vasculitis: a group of conditions that cause inflammation of the blood vessels. This can lead to symptoms such as redness, pain, and ulcerations.
5. Livedo reticularis: a condition that causes a net-like pattern of discoloration on the skin, usually on the legs. It is caused by abnormalities in the small blood vessels.
6. Henoch-Schönlein purpura: a rare condition that causes inflammation of the small blood vessels, leading to purple spots on the skin and joint pain.
7. Raynaud's phenomenon: a condition that affects the blood vessels in the fingers and toes, causing them to become narrow and restrict blood flow in response to cold temperatures or stress.

Treatment for vascular skin diseases depends on the specific condition and its severity. It may include medications, lifestyle changes, and in some cases, surgery.

A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.

For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.

It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.

"Sneddon's Syndrome". Orphanet. Retrieved 12 June 2023. "Sneddon Syndrome". Cleveland Clinic. 5 May 2022. Retrieved 12 June 2023 ... Sneddon first reported 6 patients with a distinct skin rash and cerebrovascular accidents (strokes).Sneddon's Syndrome was ... both worsen in cold and either may occur without Sneddon's syndrome or any other systemic disease.[citation needed] Sneddon's ... Sneddon's syndrome is a rare condition that is usually misdiagnosed. It occurs in families and may be inherited in an autosomal ...
Sneddon's syndrome, also known as Ehrmann-Sneddon syndrome, is also a different syndrome. Intraepidermal neutrophilic IgA ... "Sneddon's Syndrome". Orphanet. "Munks Roll Details for Peter Edward Darrell Sheldon Wilkinson". munksroll.rcplondon.ac.uk. ... IgA pemphigus is a subtype of pemphigus with two distinct forms: Subcorneal pustular dermatosis (also known as Sneddon- ...
Sneddon's syndrome This page lists people with the surname Sneddon. If an internal link intending to refer to a specific person ... Arthur Sneddon, former New Zealand wrestler Bob Sneddon (1921-2012), American football running back David Sneddon (born 1978), ... James Sneddon, Australian linguist Jamie Sneddon (born 1997), Scottish football goalkeeper (Partick Thistle FC) Kevin Sneddon ( ... Sneddon is a surname. Notable people with the surname include: Alan Sneddon (born 1958), Scottish footballer (Celtic FC, ...
... sneddon syndrome MeSH C10.228.140.300.800 - vascular headaches MeSH C10.228.140.300.850 - vasculitis, central nervous system ... cri-du-chat syndrome MeSH C10.597.606.643.210 - de lange syndrome MeSH C10.597.606.643.220 - down syndrome MeSH C10.597.606.643 ... melas syndrome MeSH C10.228.140.163.100.540 - menkes kinky hair syndrome MeSH C10.228.140.163.100.545 - merrf syndrome MeSH ... guillain-barre syndrome MeSH C10.668.829.350.500 - miller fisher syndrome MeSH C10.668.829.425 - isaacs syndrome MeSH C10.668. ...
... a rare congenital condition Sneddon syndrome - association of livedoid vasculitis and systemic vascular disorders, such as ... "Polymerase ε1 mutation in a human syndrome with facial dysmorphism, immunodeficiency, livedo, and short stature ('FILS syndrome ... Sneddon IB (April 1965). "Cerebro-Vascular Lesions And Livedo Reticularis". British Journal of Dermatology. 77 (4): 180-5. doi: ... Kazmier F, Sheps S, Bernatz P, Sayre G (1966). "Livedo reticularis and digital infarcts: a syndrome due to cholesterol emboli ...
Sneddon syndrome MeSH C17.800.862.875 - Takayasu's arteritis MeSH C17.800.862.892 - temporal arteritis MeSH C17.800.862.945 - ... Tietze syndrome MeSH C17.300.200.310 - Ehlers-Danlos syndrome MeSH C17.300.200.425 - keloid MeSH C17.300.200.425.125 - acne ... Felty's syndrome MeSH C17.300.775.099.683 - rheumatoid nodule MeSH C17.300.775.099.774 - Sjögren syndrome MeSH C17.300.775.099. ... Stevens-Johnson syndrome MeSH C17.800.229.413 - erythema nodosum MeSH C17.800.229.413.800 - Sweet's syndrome MeSH C17.800. ...
Sneddon-Wilkinson disease'), perioral dermatitis, glucagonoma syndrome, dequalinium balanitis, forefoot eczema and the first ... Sneddon, I. B.; Wilkinson, D. S. (1 December 1956). "Subcorneal Pustular Dermatosis". British Journal of Dermatology. 68 (12): ... photocontact dermatitis and Sneddon-Wilkinson disease. Described as "one of the greatest dermatologists of our time", he became ...
... sneddon syndrome MeSH C14.907.253.937 - vascular headaches MeSH C14.907.253.946 - vasculitis, central nervous system MeSH ... long QT syndrome MeSH C14.280.067.565.070 - Andersen syndrome MeSH C14.280.067.565.440 - Jervell and Lange-Nielsen syndrome ... Behcet syndrome MeSH C14.907.940.110 - Churg-Strauss syndrome MeSH C14.907.940.560 - mucocutaneous lymph node syndrome MeSH ... CREST syndrome MeSH C14.907.790.100 - anterior spinal artery syndrome MeSH C14.907.790.550 - spinal cord ischemia MeSH C14.907. ...
Magenis syndrome Snapping hip syndrome Snapping scapula syndrome Sneddon's syndrome Solipsism syndrome somatostatinoma syndrome ... syndrome Wende-Bauckus syndrome Werner syndrome Wernicke-Korsakoff syndrome West syndrome Westerhof syndrome Wet lung syndrome ... syndrome Shone's syndrome Short anagen syndrome Short bowel syndrome short limb syndrome Short man syndrome Short QT syndrome ... syndrome Radial tunnel syndrome Rage syndrome Raghib syndrome Raine syndrome Ramos-Arroyo syndrome Ramsay Hunt syndrome type 1 ...
Riby, Deborah; Doherty-Sneddon Gwyneth; Bruce, Vicki (2009). "The eyes or the mouth? Feature salience and unfamiliar face ... Early research focused on genetic disorders which impair facial recognition abilities, such as Turner syndrome, which results ... A 2003 study found significantly poorer facial recognition abilities in individuals with Turner syndrome, suggesting that the ... "Face and emotion recognition deficits in Turner syndrome: A possible role for X-linked genes in amygdala development". ...
Secondary lymphedema Septic thrombophlebitis Sinusoidal hemangioma Sneddon's syndrome (idiopathic livedo reticularis with ... Turner syndrome Ulnar-mammary syndrome Van Der Woude syndrome Von Hippel-Lindau syndrome Watson syndrome Werner syndrome (adult ... Freeman-Sheldon syndrome, Windmill-Vane-Hand syndrome) Wilson-Turner syndrome Wolf-Hirschhorn syndrome (4p- syndrome) X-linked ... Rombo syndrome Rothmund-Thomson syndrome (poikiloderma congenitale) Rud syndrome Say syndrome Scalp-ear-nipple syndrome (Finlay ...
... syndrome Smith-Fineman-Myers syndrome Smith-Lemli-Opitz syndrome Smith-Martin-Dodd syndrome Smith-Magenis syndrome Sneddon's ... Battles syndrome Sommer-Young-Wee-Frye syndrome Sondheimer syndrome Sonoda syndrome Sosby syndrome Sotos syndrome Southwestern ... syndrome Say-Barber-Hobbs syndrome Say-Barber-Miller syndrome Say-Carpenter-syndrome Say-Field-Coldwell syndrome Say-Meyer ... syndrome Stoll-Alembik-Dott syndrome Stoll-Alembik-Finck syndrome Stoll-Geraudel-Chauvin syndrome Stoll-Kieny-Dott syndrome ...
McGrogan A, Sneddon S, de Vries CS (2010). "The incidence of myasthenia gravis: a systematic literature review". ... In specific situations, testing is performed for Lambert-Eaton syndrome. Muscle fibers of people with MG are easily fatigued, ... Engel AG, Shen XM, Selcen D, Sine SM (April 2015). "Congenital myasthenic syndromes: pathogenesis, diagnosis, and treatment". ... MedlinePlus Encyclopedia: Lambert-Eaton syndrome Selvan VA (January 2011). "Single-fiber EMG: A review". Annals of Indian ...
Doherty-Sneddon points out that baby sign is not entirely new. Variations have been used by speech and language therapists for ... "Strategies for achieving joint attention when signing to children with Down's syndrome". International Journal of Language & ... Doherty-Sneddon also states a key issue is ensuring that sufficient and appropriately designed research is available to back ... Doherty-Sneddon, G. (2008). "The great baby signing debate". The Psychologist. 21 (4): 300-303. Porpora, T (2011). The Complete ...
He suffers from locked-in syndrome after a suicide attempt in his car. All the characters and events Goodman has experienced ... as the voice of Mike from Barnet Derren Brown as the voice of Betty Elaine Dyson as the voice of Mrs Rifkind Billy Sneddon as ... who suffers from locked-in syndrome. He was haunted by the spirit of a young girl while working in a disused asylum for women. ...
Heisterkamp N, Groffen J, Warburton D, Sneddon TP (Apr 2008). "The human gamma-glutamyltransferase gene family". Hum Genet. 123 ... "Low-copy repeats mediate the common 3-Mb deletion in patients with velo-cardio-facial syndrome". Am. J. Hum. Genet. 64 (4): ...
Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human ... 1987). "Myo-, neuro-, gastrointestinal encephalopathy (MNGIE syndrome) due to partial deficiency of cytochrome-c-oxidase. A new ... and MNGIE due to its role in MNGIE syndrome. The TYMP gene is located on chromosome 22 in humans and contains 10 exons spanning ...
... can be inherited in isolation or in association with genetic syndromes, such as Marfan syndrome and Loeys-Dietz syndrome. When ... Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human ... 2006). "Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ...
Sneddon, Julie B.; Burt, Trevor D.; Gardner, James M. (December 2021). "Single-cell transcriptional profiling of human thymic ... presenting as a complete DiGeorge syndrome or severe combined immune deficiency (T−B+NK+ SCID). There is large evidence ...
But after the birth of their second child, Alice, who was born with Down's syndrome, Max was arrested on suspicion of kerb ... Marcus Sneddon. This storyline culminated in another hostage situation where Ollie, Eleanor, Louise and Danny are held at ... The shorthand explanation is I'm giving up the lesbian-affair-with-the-mother-in-law syndrome. We've been there, done that and ...
District attorney Sneddon and Lauren Weis, head of the county DA's Sex Crimes Unit, said that ending the investigation did not ... Gardner had formulated Parental Alienation Syndrome (PAS) in 1985, a disorder that arises primarily in the context of child- ... Sneddon said several leads were explored which were later discovered to be false. According to the grand juries, the evidence ... Sneddon again led the prosecution. The People v. Jackson trial began in Santa Maria, California, on January 31, 2005. The judge ...
Sneddon, Laura (11 May 2016). "Meet the Magical Bad Girls of 'Jade Street Protection Services' [Interview / Preview]". ... In her defense, Dame Edna insists she has "mild Asperger's syndrome" and "says the things other people wished they could say" ... "Radha Mitchell on 'Mozart and the Whale' and Researching Asperger's Syndrome". About.com. Archived from the original on 24 ... Neil Admur (3 August 2009). "Asperger's Syndrome, on Screen and in Life". The New York Times. Retrieved 19 March 2012. " ...
Isaacman, Allen; Sneddon, Chris (2000). "Toward a Social and Environmental History of the Building of Cahora Bassa Dam". ... In September 2007, epizootic ulcerative syndrome (EUS) killed hundreds of sore-covered fish in the river. Zambia agriculture ...
Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, ... In a phase 1 trial of Pevonedistat to determine dosing in patients with AML and myelodysplastic syndromes "modest clinical ... in patients with acute myeloid leukaemia and myelodysplastic syndromes: a phase 1 study" (PDF). British Journal of Haematology ...
Davie Sneddon, 84, Scottish footballer (Kilmarnock, Preston North End, Raith Rovers). Geoff Stephens, 86, English songwriter (" ... complications from myelodysplastic syndrome. David Giler, 77, American screenwriter (The Parallax View, The Money Pit) and film ... Smith Sadness as Kilmarnock league winning legend David Sneddon MBE dies Geoff Stephens Passed Away Siv Widerberg är död (in ...
13 December - David Sneddon wins the first series of Fame Academy. 15 December - On the Record, the BBC's flagship political ... Tooze, Steve (23 February 2002). "I swear I'm going to be normal now; Tourette's Syndrome sufferer John Davidson highlighted ... John's Not Mad which deals with sufferers of Tourette syndrome. 28 February - The Bill switches to a serial format. 1 March - ...
Robert Adams Sneddon, Chief Registrar, Glasgow City Council. For services to Registration in Scotland. Victor Spence, Treasurer ... For Charitable Services, especially to the Arts and the Tourette Syndrome (UK) Association. Christos Kavallares, Chair, ...
Churg-Strauss syndrome) Acute and chronic eosinophilic pneumonia Mycosis fungoides (MF) Sezary syndrome (SS) Lymphocytic ... Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, et al. (September 1999). "Genome duplications and other ... Maculopapular exanthema Stevens-Johnson syndrome/toxic epidermal necrolysis (Non-)episodic angioedema with eosinophilia ...
Raymond John Sneddon - For service to sports administration, and to the community. Owen Lindsay Sperling - For service to ... particularly to those with CHARGE syndrome. Dr Ross Kenneth Littlewood - For significant service to medicine as an ...
Sneddon, Joey (December 21, 2011). "Linux Users Continue To Pay Most for the @Humble Indie Bundle". OMG! Ubuntu!. Retrieved ... Camel 101 and Bigmoon Entertainment released Syndrome, Adam Pype released No Players Online, Arbitrary Metric released ... Sneddon, Joey (March 19, 2019). "Stadia is Google's New Gaming Service Powered by Linux & Open-Source Tech". OMG Ubuntu. ...
"Sneddons Syndrome". Orphanet. Retrieved 12 June 2023. "Sneddon Syndrome". Cleveland Clinic. 5 May 2022. Retrieved 12 June 2023 ... Sneddon first reported 6 patients with a distinct skin rash and cerebrovascular accidents (strokes).Sneddons Syndrome was ... both worsen in cold and either may occur without Sneddons syndrome or any other systemic disease.[citation needed] Sneddons ... Sneddons syndrome is a rare condition that is usually misdiagnosed. It occurs in families and may be inherited in an autosomal ...
Case Report: Diagnosing Sneddon Syndrome. Emily Jean Katz, PA-C, Kelsey Hennig, PharmD, BCPS, Mitchell Miller, PharmD, & ... The biopsy demonstrated histological findings characteristic of Sneddon syndrome, with obliterative vasculopathy, and changes ... Sneddon syndrome was a concern. The patients case was discussed with her current hematologist, who agreed that anticoagulation ... were concerning for Sneddon syndrome. Due to the concern for further strokes without a known associated cause, a dermatologist ...
Genetic Testing Registry: Sneddon syndrome *Genetic Testing Registry: Vasculitis due to ADA2 deficiency ...
Sneddons Syndrome: Generalized Livedo reticularis and Cerebrovascular Disease: Importance of Hemostatic Screening Subject Area ... View articletitled, Sneddons Syndrome: Generalized Livedo reticularis and Cerebrovascular Disease,span class=subtitle-colon ... Apudoma and Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease) Subject Area: Dermatology , Immunology and Allergy ... A Case of Omenn-Like Immunodeficiency Syndrome Subject Area: Dermatology , Immunology and Allergy ...
These include Fabry disease, Moyamoya angiopathy, Sneddon syndrome, Susac syndrome and Takotsubo syndrome. ...
40Capsular Warning Syndrome: not all TIAs remain the same. Livedo racemosa in Sneddon Syndrome: a mysterious hint to recognise ... 06Livedo racemosa in Sneddon Syndrome: a mysterious hint to recognise a rare stroke etiology. ... Capsular Warning Syndrome: not all TIAs remain the same. 01/04/2022. ...
Cutis marmorata; Livedo reticularis - idiopathic; Sneddon syndrome - idiopathic livedo reticularis; Livedo racemosa ... that involve the blood such as abnormal proteins or high risk of developing blood clots such as antiphospholipid syndrome ...
The mystery of Sneddon syndrome: relationship with antiphospholipid syndrome and systemic lupus erythematosus. J Autoimmun. ... In both antiphospholipid antibody syndrome and primary antiphospholipid antibody syndrome, the frequency rate related to sex is ... encoded search term (Pediatric Antiphospholipid Antibody Syndrome) and Pediatric Antiphospholipid Antibody Syndrome What to ... Essential thrombocytosis and antiphospholipid antibody syndrome causing chronic budd-Chiari syndrome. Indian J Pediatr. 2012 ...
Sneddon-Wilkinson syndrome or subcorneal pustular dermatosis (SCPD): The disease follows a relapsing and remitting course that ...
Sneddons Syndrome (Livedo Racemosa and Cerebral Infarction) Presenting Psychiatric Disturbance and Shortening of Fingers and ... A skin biopsy of the livedo lesion revealed endoarteritis obliterans, being compatible with Sneddons syndrome. MRI of the ... In immotile cilia syndrome (ICS), respiratory symptoms show a wide range of severity. Various types of axonemal abnormalities ... Reflection of Structural Abnormality in the Axoneme of Respiratory Cilia in the Clinical Features of Immotile Cilia Syndrome ...
These are associated with a wide number of conditions but of particular interest is Sneddons syndrome, which describes the ...
Disease Name: Sneddon syndrome OMIM id: OMIM:182410. Orphanet id: Orphanet:820. All associated enzymes in DAR: ADA2 ... Disease Name: Omenn syndrome OMIM id: OMIM:603554. Orphanet id: Orphanet:39041. All associated enzymes in DAR: CHD7 RAG1 ...
Adenosine Deaminase 2 Deficiency; PID autoinflammatory diseases ; Primary immunodeficiencies and skin; Sneddon syndrome; ... Deficiency of ADA2 (DADA2) is the first molecularly described monogenic vasculitis syndrome. Over 60 disease-associated ... Lee PY (2018) Vasculopathy, immunodeficiency, and bone marrow failure: the intriguing syndrome caused by deficiency of ... Vasculitis, autoinflammation, immunodeficiency, and hematologic defect syndrome (first manifestation as early as infancy- ...
Sneddons syndrome. A long-term follow-up of 21 patients.. Zelger B, Sepp N, Stockhammer G, Dosch E, Hilty E, Ofner D, Aichner ... Sneddon Syndrome: A Comprehensive Overview.. Samanta D, Cobb S, Arya K. J Stroke Cerebrovasc Dis 2019 Aug;28(8):2098-2108. Epub ... Sneddon Syndrome: A Comprehensive Overview.. Samanta D, Cobb S, Arya K. J Stroke Cerebrovasc Dis 2019 Aug;28(8):2098-2108. Epub ... Sneddon Syndrome: A Comprehensive Overview.. Samanta D, Cobb S, Arya K. J Stroke Cerebrovasc Dis 2019 Aug;28(8):2098-2108. Epub ...
Sneddon syndrome From NCATS Genetic and Rare Diseases Information Center. * Factor V Leiden mutation in Sneddon syndrome. ...
Susac syndrome is typically a triad of encephalopathy, retinopathy, and hearing loss, but may have an atypical presentation. ... Sneddon syndrome. Sneddon syndrome is a rare progressive disorder affecting small- and medium-sized blood vessels, especially ... Susac syndrome. Medicine 1998;77:3-11. PMID 9465860 84 Papo T, Klein I, Sacré K, et al. Susac syndrome. [French] Rev Med ... Management of Susac syndrome is also discussed.. Key points. • Susac syndrome is typically a triad of encephalopathy, ...
Susacs syndrome. *. Sneddons syndrome (antiphospholipid antibody syndrome). *. Chronic inflammatory demyelinating ... The administration of disease-modifying medications in the clinically isolated syndrome has been repeatedly demonstrated to ...
Antiphospholipid antibody positive Sneddon syndrome: a case report. Tosunoglu, Bünyamin; Basut, Fadima Serap; Baser, Beyza; ... Sneddon syndrome often affects women. Since it is vasculopathy affecting small and medium vessels, other organ findings may ... Sneddon syndrome may present with neurological findings such as transient ischemic stroke, strokes, seizures and/or headaches. ... We present a 44-year-old Sneddon syndrome patient with monoparesis in her left lower extremity, livedo reticularis on her back ...
Sneddon Syndrome: A Comprehensive Overview.. Samanta D, Cobb S, Arya K. J Stroke Cerebrovasc Dis 2019 Aug;28(8):2098-2108. Epub ... Sneddon Syndrome: A Comprehensive Overview.. Samanta D, Cobb S, Arya K. J Stroke Cerebrovasc Dis 2019 Aug;28(8):2098-2108. Epub ... Sneddon Syndrome: A Comprehensive Overview.. Samanta D, Cobb S, Arya K. J Stroke Cerebrovasc Dis 2019 Aug;28(8):2098-2108. Epub ... Prader-Willi Syndrome: Possibilities of Weight Gain Prevention and Treatment.. Erhardt É, Molnár D. Nutrients 2022 May 6;14(9) ...
Sneddons syndrome ,SS, [also. Sneddon. syndrome]. Sneddon-Syndrom {n}. comp.. software system ,SS, SWS,. Softwaresystem {n}. , ...
Livedo reticularis with systemic involvement and stroke is SNEDDON SYNDROME.. Allowable Qualifiers:. BL blood. CF cerebrospinal ... Livedo reticularis with systemic involvement and stroke is SNEDDON SYNDROME. ... It is more associated with other syndromes (e.g., PROTEIN C DEFICIENCY; HYPERHOMOCYSTEINEMIA). ... It is more associated with other syndromes (e.g., PROTEIN C DEFICIENCY; HYPERHOMOCYSTEINEMIA). ...
No article was found for Sneddon Syndrome and F5[original query]. File Formats Help:. How do I view different file formats (PDF ...
Sneddon syndrome: under diagnosed disease, complex clinical manifestations and challenging diagnosis. A case-based review., ... Seizure as an Initial Presentation for Posterior Reversible Encephalopathy Syndrome in Undiagnosed Systemic Lupus Erythematosus ...
The mystery of Sneddon syndrome: relationship with antiphospholipid syndrome and systemic lupus erythematosus. J Autoimmun. ... In both antiphospholipid antibody syndrome and primary antiphospholipid antibody syndrome, the frequency rate related to sex is ... encoded search term (Pediatric Antiphospholipid Antibody Syndrome) and Pediatric Antiphospholipid Antibody Syndrome What to ... Essential thrombocytosis and antiphospholipid antibody syndrome causing chronic budd-Chiari syndrome. Indian J Pediatr. 2012 ...
Acute Central Retinal Artery Occlusion Associated with Livedoid Vasculopathy: A Variant of Sneddons Syndrome Hyun Beom Song, ... A Case of Susac Syndrome Han Joo Cho, Chul Gu Kim, Sung Won Cho, Jong Woo Kim Korean J Ophthalmol. 2013;27(5):381-383. ...
RIBY, D. M.; DOHERTY-SNEDDON, G.; BRUCE, V. The eyes or the mouth? Feature salience and unfamiliar face processing in Williams ... syndrome and autism. Quarterly Journal of experimental psychology, v. 62, n. 1, p. 189-203, 2009. doi: 10.1080/ ...
... lenticulostriate aneurysm causing intraventricular haemorrhage in a patient with antiphospholipid-negative Sneddons syndrome ...
Sneddon syndrome is a rare progressive disorder affecting the blood vessels characterized by the association of a skin ... Chiari i syndrome. The particular type of malformation and the evolution of anatomical changes or symptoms strongly influence ... Moyamoya syndrome is a progressive disorder that affects the blood vessels in the brain (cerebrovascular). It is characterized ... Tolosa-Hunt syndrome is a rare disorder characterized by severe periorbital headaches, along with decreased and painful eye ...
... including autism and Williams syndrome. I have been fortunate to receive over £800,000 in ESRC research grants during my career ... Being Gwyneth Doherty-Sneddon. Posted on 22 March, 2017. by Susanne What route has your career taken to get you where you are ...
... and Sneddon syndrome. Skin ulcerations, especially in lower extremities ranging from small ulcers to large ulcers resembling ... Subtypes: Catastrophic antiphospholipid syndrome. Causes of Antiphospholipid Syndrome. Antiphospholipid syndrome (APS) is ... What is Rett syndrome? - Causes, Symptoms, Treatment. Rett syndrome is a neurodevelopmental disorder that affects girls almost ... Carpal Tunnel Syndrome - Causes, Symptoms, Treatment. Carpal tunnel syndrome may be defined as paresthesia itching, numbness, ...
  • Dr Gwyneth Doherty-Sneddon of the Department of Psychology will argue that during difficult cognitive activity (e.g. thinking of an answer to a challenging question) we often look away from the person we are in conversation with. (stir.ac.uk)
  • Dr Doherty-Sneddon said: "We have recently shown that looking at someone's face can sometimes interfere with our abilities to remember and process information. (stir.ac.uk)
  • Dr Doherty-Sneddon said: "Gaze aversion therefore promises to be a useful tool in many situations including pedagogical ones. (stir.ac.uk)
  • Doherty-Sneddon G, Riby D, Calderwood L & Ainsworth L (2009) Stuck on you: Face-to-face arousal and gaze aversion in Williams syndrome. (stir.ac.uk)
  • Doherty-Sneddon_Riby_et_al_32finalversion31.pdf] Publisher conditions require an 18 month embargo. (stir.ac.uk)
  • Sneddon's syndrome is a form of arteriopathy characterized by several symptoms, including: Severe, transient neurological symptoms or stroke Livedo reticularis, or livedo racemosa Sneddon's syndrome generally manifests with stroke or severe, transient neurological symptoms, and a skin rash (livedo reticularis). (wikipedia.org)
  • Sneddon's syndrome may instead present with livedo racemosa, which involves larger, less organized patches of bluish-purple mottling of the skin. (wikipedia.org)
  • The case was discussed with the patient's dermatologist, who agreed that based on evidence of a pattern consistent with livedo racemosa (see Figures 1-4, opposite) and characteristic biopsy findings, Sneddon syndrome was a concern. (the-rheumatologist.org)
  • Livedo reticularis of the upper and lower extremities in a 15-year-old adolescent with primary antiphospholipid antibody syndrome. (medscape.com)
  • Sneddon syndrome is a noninflammatory arteriopathy characterized by onset of livedo reticularis in the second decade and onset of cerebrovascular disease in early adulthood (summary by Bras et al. (nih.gov)
  • Livedo reticularis with systemic involvement and stroke is SNEDDON SYNDROME. (bvsalud.org)
  • Sneddon-Wilkinson syndrome or subcorneal pustular dermatosis (SCPD): The disease follows a relapsing and remitting course that may develop into generalized pustular psoriasis. (medscape.com)
  • Complete remission of skin lesions in a patient with subcorneal pustular dermatosis (Sneddon-Wilkinson disease) treated with anti-myeloma therapy: association with disappearance of M-protein. (myeloma.org.uk)
  • Deficiency of ADA2 (DADA2) is the first molecularly described monogenic vasculitis syndrome. (altmeyers.org)
  • Lee PY (2018) Vasculopathy, immunodeficiency, and bone marrow failure: the intriguing syndrome caused by deficiency of adenosine deaminase 2. (altmeyers.org)
  • 1. AIDS: Acquired immune deficiency syndrome Acquired immunodeficiency syndrome 2. (cdc.gov)
  • The biopsy demonstrated histological findings characteristic of Sneddon syndrome, with obliterative vasculopathy, and changes that included fibrous replacement of medium caliber vascular structures with focal recanalization. (the-rheumatologist.org)
  • Sneddon's syndrome is a progressive, noninflammatory arteriopathy leading to the characteristic skin condition and to cerebrovascular problems, including stroke, transient ischemic attack (TIA), severe but transient neurological symptoms thought to be caused by cerebral vasospasm, coronary disease and early-onset dementia. (wikipedia.org)
  • In 1965, Dr. Sneddon first reported 6 patients with a distinct skin rash and cerebrovascular accidents (strokes).Sneddon's Syndrome was formerly understood to be a type of autoimmune disease called antiphospholipid syndrome, although it has been reclassified as a noninflammatory cerebrovascular disease. (wikipedia.org)
  • Moyamoya syndrome is a progressive disorder that affects the blood vessels in the brain (cerebrovascular). (brainandnervecenter.com)
  • The presence of antiphospholipid antibodies and a vaso-occlusive event superimposed on an underlying disease, such as SLE or malignancy, is a secondary antiphospholipid antibody syndrome. (medscape.com)
  • Susac syndrome presents with a triad of retinal arterial occlusion, deafness, and encephalopathy, although often not all of the components are evident at the onset. (medlink.com)
  • Management of Susac syndrome is also discussed. (medlink.com)
  • Susac syndrome is typically a triad of encephalopathy, retinopathy, and hearing loss, but may have an atypical presentation. (medlink.com)
  • Susac syndrome is characterized by a triad of encephalopathy, retinopathy, and hearing loss. (medlink.com)
  • The triad of clinical features in Susac syndrome is encephalopathy, retinopathy, and hearing loss. (medlink.com)
  • the authors suggested classifying the disease course into suspected, incomplete, and complete Susac syndrome to facilitate early diagnosis. (medlink.com)
  • Sneddon syndrome is a rare progressive disorder affecting the blood vessels characterized by the association of a skin condition and neurological abnormalities. (brainandnervecenter.com)
  • Antiphospholipid syndrome is an acquired autoimmune disorder characterized by recurrent arterial or venous thrombosis and/or pregnancy losses, in the presence of persistently elevated levels of anticardiolipin antibodies and/or evidence of circulating lupus anticoagulant (these abnormalities are detected by blood tests). (endinglines.com)
  • Goltz syndrome (focal dermal hypoplasia), a very rare syndrome that predominates in girls, is characterized by various ectodermal and mesodermal abnormalities. (tripod.com)
  • My most recent work has investigated gaze aversion as cognitive load management in people with neurodevelopmental disorders, including autism and Williams syndrome. (ncl.ac.uk)
  • In addition, they are beginning the first studies of gaze aversion as mental load management with special needs children, including children with William's syndrome and attention hyperactivity disorder. (stir.ac.uk)
  • We investigate whether individuals with Williams syndrome (WS), associated with hyper-sociability and atypical face gaze, use GA to manage cognitive load and whether physiological arousal is associated with looking at faces. (stir.ac.uk)
  • The patient's age, livedo and middle cerebral artery infarct, as well as her nonrevealing workup on repeat antiphospholipid antibody labs and hypercoagulable studies, were concerning for Sneddon syndrome. (the-rheumatologist.org)
  • Hughes Syndrome/Antiphospholipid syndrome (APS) is a systemic autoimmune, hypercoagulable, thrombo inflammatory, and thrombosis and/or pregnancy complications syndrome caused by the persistent presence of antiphospholipid antibodies (APL) in plasma of patients with vascular thrombosis and/or pregnancy morbidity along with persistent anti-phospholipid antibodies (APLA), including lupus anticoagulant (LA), anti-β2-glycoprotein I (anti-β2GPI) and/or anti-cardiolipin (ACL) antibodies. (endinglines.com)
  • About 40-60% of patients with the syndrome test positive for antiphospholipid antibodies. (wikipedia.org)
  • Antiphospholipid antibodies associated with vaso-occlusive events without any underlying disease process is termed the primary antiphospholipid antibody syndrome (PAPS). (medscape.com)
  • Preliminary classification criteria for "definite" antiphospholipid antibody syndrome were proposed in a report from the Eighth International Symposium on Antiphospholipid Antibodies and were published in Arthritis and Rheumatism . (medscape.com)
  • Although features such as migraine headache, peripheral vasospasm, and thrombocytopenia were excluded from the published criteria, they were argued to be valid and useful clinical parameters in arriving at the diagnosis of antiphospholipid antibody syndrome in the clinical setting at the Ninth International Symposium on Antiphospholipid Antibodies. (medscape.com)
  • In a consensus conference held at the 11th International Symposium on Antiphospholipid Antibodies, existing evidence on clinical and laboratory features of antiphospholipid antibody syndrome was appraised and amendments to the Sapporo criteria were proposed. (medscape.com)
  • Antiphospholipid syndrome (APS) is caused by the body's immune system producing abnormal antibodies called antiphospholipid antibodies. (endinglines.com)
  • Diabetes & Metabolic Syndrome: Clinical Research & Reviews , 102881. (otago.ac.nz)
  • The advent of disease-modifying medications appears to have significantly altered the course of MS. The administration of disease-modifying medications in the clinically isolated syndrome has been repeatedly demonstrated to delay the progression to clinically definite MS. [ 2 , 3 ] Not only may this therapy decrease relapse rates and new MRI lesions, but it may also reduce the development of confirmed disability. (medscape.com)
  • Both are generally found first in the extremities, both worsen in cold and either may occur without Sneddon's syndrome or any other systemic disease. (wikipedia.org)
  • Sneddon's syndrome is a rare condition that is usually misdiagnosed. (wikipedia.org)
  • Sneddon's syndrome most often becomes apparent in women in their thirties, though cases do occur in men and in children. (wikipedia.org)
  • Antiphospholipid antibody syndrome is a systemic autoimmune disorder that can manifest clinically as recurrent thrombosis. (medscape.com)
  • Antiphospholipid syndrome is an autoimmune disorder of unknown cause. (endinglines.com)
  • In general, the treatment of antiphospholipid antibody syndrome is individualized according to the patient's clinical status and history of thrombotic events. (medscape.com)
  • Sneddon syndrome: under diagnosed disease, complex clinical manifestations and challenging diagnosis. (hcahealthcare.com)
  • Catastrophic antiphospholipid antibody syndrome is a multisystem failure secondary to thrombosis, infarction, or both and is characterized by microangiopathy on histopathologic examination. (medscape.com)
  • Feature salience and unfamiliar face processing in Williams syndrome and autism. (bvsalud.org)
  • Results: In study 1, whilst WS was associated with general hypo-arousal, face arousal effects were found for both Williams syndrome and typically developing participants. (stir.ac.uk)
  • Tolosa-Hunt syndrome is a rare disorder characterized by severe periorbital headaches, along with decreased and painful eye movements (ophthalmoplegia). (brainandnervecenter.com)
  • [ 1 ] The criteria for the diagnosis of pediatric antiphospholipid antibody syndrome have not yet been validated. (medscape.com)
  • In this article, the author describes the clinical features, pathology, and diagnosis of this syndrome as well as atypical presentations. (medlink.com)
  • In partial or variant forms of this syndrome, only one or two of the three components are clinically manifest. (medlink.com)
  • Therefore, in order to address the needs of clinicians and to expand the data for future research, the discussion included definitions on features of antiphospholipid antibody syndrome that were not included in the updated criteria for use clinically and in research. (medscape.com)
  • Spontaneous Osteonecrosis of the Jaw During Bisphosphonate Therapy: An Unusual Etiology of the Numb Chin Syndrome. (myeloma.org.uk)
  • In patients with primary antiphospholipid antibody syndrome with venous thrombosis, the initial treatment consists of heparin followed by warfarin or low molecular weight heparin. (medscape.com)
  • In patients with primary antiphospholipid antibody syndrome with arterial thrombosis or infarction, many physicians administer antiplatelet therapy in the absence of other risk factors, but the use of anticoagulants is controversial. (medscape.com)
  • These were published as the "International Consensus Statement on an Update of the Classification Criteria for Definite Antiphospholipid Antibody Syndrome (APS)" in J Thrombosis Haemost . (medscape.com)
  • CHILD syndrome (congenital hemidysplasia with ichthyosiform erythroderma and limb defects) is a very rare syndrome. (tripod.com)
  • If the clinical features suggest an antiphospholipid antibody syndrome, a thorough evaluation to detect the presence of at least one of these antibodies is essential. (medscape.com)
  • AIDS-like syndrome: AIDS-like disease (illness) (syndrome) ARC AIDS-related complex Pre-AIDS AIDS-related conditions Prodromal-AIDS 3. (cdc.gov)
  • The purpose of the report was to define the essential features of antiphospholipid antibody syndrome in order to facilitate studies of treatment and causation. (medscape.com)
  • Oral facial-digital syndrome type 1 ( OFD-1 ) is inherited in an X-linked dominant pattern. (tripod.com)
  • The problem that dogs the work of all of those treating patients with antiphospholipid syndrome (APS) is the apparent lack of knowledge of the syndrome, both by the general public, as well as by swaths of the medical fraternity. (the-rheumatologist.org)
  • Vasospastic or vaso-occlusive events can occur in any organ system in patients with antiphospholipid antibody syndrome. (medscape.com)
  • Asymptomatic Chiari I syndrome should be ignored (this involves most Chiari malformations). (brainandnervecenter.com)