Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
Neoplasms developing from some structure of the connective and subcutaneous tissue. The concept does not refer to neoplasms located in connective or soft tissue.
Neoplasms composed of bony tissue, whether normal or of a soft tissue which has become ossified. The concept does not refer to neoplasms located in bones.
Neoplasms composed of tissues of the OVARY or the TESTIS, not neoplasms located in the ovaries or testes. Gonadal tissues include GERM CELLS, cells from the sex cord, and gonadal stromal cells.
Neoplasms composed of fatty tissue or connective tissue made up of fat cells in a meshwork of areolar tissue. The concept does not refer to neoplasms located in adipose tissue.
Neoplasms composed of nerve tissue. This concept does not refer to neoplasms located in the nervous system or its component nerves.
Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue.
Neoplasms composed of vascular tissue. This concept does not refer to neoplasms located in blood vessels.
Neoplasms composed of fibrous tissue, the ordinary connective tissue of the body, made up largely of yellow or white fibers. The concept does not refer to neoplasms located in fibrous tissue.
A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Neoplasms composed of muscle tissue: skeletal, cardiac, or smooth. The concept does not refer to neoplasms located in muscles.
Injuries of tissue other than bone. The concept is usually general and does not customarily refer to internal organs or viscera. It is meaningful with reference to regions or organs where soft tissue (muscle, fat, skin) should be differentiated from bones or bone tissue, as "soft tissue injuries of the hand".
Infections of non-skeletal tissue, i.e., exclusive of bone, ligaments, cartilage, and fibrous tissue. The concept is usually referred to as skin and soft tissue infections and usually subcutaneous and muscle tissue are involved. The predisposing factors in anaerobic infections are trauma, ischemia, and surgery. The organisms often derive from the fecal or oral flora, particularly in wounds associated with intestinal surgery, decubitus ulcer, and human bites. (From Cecil Textbook of Medicine, 19th ed, p1688)
Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.
The anteriorly located rigid section of the PALATE.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
The part of the face that is below the eye and to the side of the nose and mouth.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
Surgical reshaping of the gingivae and papillae for correction of deformities (particularly enlargements) and to provide the gingivae with a normal and functional form, the incision creating an external bevel. (Dorland, 28th ed)

L-[1-11C]-tyrosine PET to evaluate response to hyperthermic isolated limb perfusion for locally advanced soft-tissue sarcoma and skin cancer. (1/1415)

PET with L-[1-11C]-tyrosine (TYR) was investigated in patients undergoing hyperthermic isolated limb perfusion (HILP) with recombinant tumor necrosis factor alpha (rTNF-alpha) and melphalan for locally advanced soft-tissue sarcoma and skin cancer of the lower limb. METHODS: Seventeen patients (5 women, 12 men; age range 24-75 y; mean age 52 y) were studied. TYR PET studies were performed before HILP and 2 and 8 wk afterwards. The protein synthesis rates (PSRs) in nanomoles per milliliter per minute were calculated. After final PET studies, tumors were resected and pathologically examined. Patients with pathologically complete responses (pCR) showed no viable tumors after treatment. Those with pathologically partial responses (pPR) showed various amounts of viable tumors in the resected tumor specimens. RESULTS: Six patients (35%) showed a pCR and 11 patients (65%) showed a pPR. All tumors were depicted as hot spots on PET studies before HILP. The PSR in the pCR group at 2 and 8 wk after perfusion had decreased significantly (P < 0.05) in comparison to the PSR before HILP. A significant difference was found in PSR between the pCR and pPR groups at 2 and at 8 wk (P < 0.05). Median PSR in nonviable tumor tissue was 0.62 and ranged from 0.22 to 0.91. With a threshold PSR of 0.91, sensitivity and specificity of TYR PET were 82% and 100%, respectively. The predictive value of a PSR > 0.91 for having viable tumor after HILP was 100%, whereas the predictive value of a PSR < or = 0.91 for having nonviable tumor tissue after HILP was 75%. The 2 patients in the pPR groups with a PSR < 0.91 showed microscopic islets of tumor cells surrounded by extensive necrosis on pathological examination. CONCLUSION: Based on the calculated PSR after HILP, TYR PET gave a good indication of the pathological outcome. Inflammatory tissue after treatment did not interfere with viable tumor on the images, suggesting that it may be worthwhile to pursue TYR PET in other therapy evaluation settings.  (+info)

FDG and L-[1-11C]-tyrosine imaging of soft-tissue tumors before and after therapy. (2/1415)

This study was undertaken to investigate the relationship of PET using fluorodeoxyglucose (FDG) or L-[1-11C]-tyrosine (TYR) with histopathologic findings in soft-tissue tumors, before and after therapy. Histopathologic parameters that were studied were tumor grade, mitotic rate, proliferation activity and amount of necrosis. METHODS: PET with either FDG or TYR was performed in 55 patients with a lesion suspected to be a malignant soft-tissue tumor. In 28 patients, a second PET study was performed after therapy. Metabolic rate of glucose consumption (MRglc) and protein synthesis rate (PSR) were calculated. Histologic parameters were obtained from a biopsy specimen that was taken just after the first PET study and from the tumor remnant that was resected after therapy. RESULTS: MRglc correlated with tumor grade (r = 0.71) and mitotic rate (r = 0.68) but not with proliferation or necrosis. After therapy, there was no longer a correlation with mitotic rate. PSR correlated with tumor grade (r = 0.53), mitotic rate (r = 0.73) and proliferation (r = 0.66). After therapy, correlation with mitosis and proliferation had improved, and a negative correlation was found between PSR and necrosis (r = -0.74). CONCLUSION: These results validate the use of both FDG and TYR to give an in vivo indication of histologic tumor parameters. However, FDG gives a better indication of tumor grade, whereas TYR is more accurate in predicting mitotic rate and proliferation, especially after therapy. FDG may therefore not be the most suited tracer for monitoring therapy. TYR might be more appropriate for that purpose.  (+info)

Subcutaneous sacrococcygeal myxopapillary ependymoma. (3/1415)

We report a case of myxopapillary ependymoma presenting as a primary tumor of the subcutaneous tissue in the sacrococcygeal region. The mass was large, well-encapsulated, lobulated, and multiseptated, with varying signal intensity on T1- and T2-weighted MR images caused by hemorrhagic necrosis, blood degradation products, and calcification. Only a small viable portion enhanced after administration of contrast material. Multiple lobules formed from fibrous septa and dystrophic calcification also characterize this tumor.  (+info)

Lymphangiosarcomas in cats: a retrospective study of 12 cases. (4/1415)

Clinical, macroscopic, and histologic features of 12 lymphangiosarcomas in cats are described. Nine tumors were located in the subcutaneous tissue at the caudoventral abdominal wall (eight cats) or in the neck (one cat). The remaining three cats had lymphangiosarcomas around the cranial mesenteric artery (two cats) or precardial in the mediastinum (one cat). Macroscopically, the tumors were noncircumscribed, white, edematous, and intermixed with fat tissue. Histologic features varied from cleft-forming and cavernous growth to papilliform and solid patterns. Follow-up data were available for seven cats with subcutaneous lymphangiosarcomas. All these cats died or were euthanatized within 6 months after surgery because of poor wound healing, local recurrence, or distant metastases. The cats with abdominal or thoracic masses were either euthanatized at surgery or within 6 months after the first surgery because of recurrent chylothorax, chyloperitoneum, or distant metastases.  (+info)

Clinical and radiological aspects of idiopathic diabetic muscle infarction. Rational approach to diagnosis and treatment. (5/1415)

The systemic effects of diabetes mellitus are well recognised. The heart, kidney, central and peripheral nervous systems, and the distal parts of the limbs are often the site of end-organ damage resulting from ischaemia. Infarction of large muscle groups in the limb, not associated with gangrene, is uncommon. There have been few reported cases other than radiological descriptions of diabetic muscle infarcts. While previous reports have illustrated some of the clinical and radiological characteristics of this condition, the paucity of published cases makes it difficult to determine the most appropriate methods of diagnosis and treatment. During a five-year period we treated 14 patients with diabetes mellitus, aged from 32 to 59 years, who were referred to a musculoskeletal oncology service for suspected soft-tissue sarcoma, but were subsequently found to have a diabetic muscle infarct. Closed needle biopsy was performed in 13 without complications. In 12 patients, the symptoms resolved without surgical treatment.  (+info)

Color Doppler sonography of focal lesions of the skin and subcutaneous tissue. (6/1415)

We evaluated with color Doppler sonography 71 visible and palpable nodules of the skin and subcutaneous tissue from 51 patients. The nodules were classified as avascular (type I), hypovascular with a single vascular pole (type II), hypervascular with multiple peripheral poles (type III), and hypervascular with internal vessels (type IV). Of the 32 malignant nodules, 9% showed a type I pattern, 50% had a type III pattern, and 41% had a type IV pattern; of the 39 benign nodules, 86% showed a type I pattern and 14% had a type II pattern. The sensitivity and specificity of hypervascularity in malignant lesions were 90% and 100%, respectively, whereas the sensitivity and specificity of hypovascularity in benign lesions were 100% and 90%, respectively. The authors conclude that color Doppler sonography is able to increase the specificity of ultrasonography in the evaluation of nodular lesions of the skin.  (+info)

Pulmonary metastases from soft tissue sarcoma: analysis of patterns of diseases and postmetastasis survival. (7/1415)

OBJECTIVE: To report the patterns of disease and postmetastasis survival for patients with pulmonary metastases from soft tissue sarcoma in a large group of patients treated at a single institution. Clinical factors that influence postmetastasis survival are analyzed. SUMMARY BACKGROUND DATA: For patients with soft tissue sarcoma, the lungs are the most common site of metastatic disease. Although pulmonary metastases most commonly arise from primary tumors in the extremities, they may arise from almost any primary site or histology. To date, resection of disease has been the only effective therapy for metastatic sarcoma. METHODS: From July 1982 to February 1997, 3149 adult patients with soft tissue sarcoma were admitted and treated at Memorial Sloan-Kettering Cancer Center. During this interval, 719 patients either developed or presented with lung metastases. Patients were treated with resection of metastatic disease whenever possible. Disease-specific survival was the endpoint of the study. Time to death was modeled using the method of Kaplan and Meier. The association of factors to time-to-event endpoints was analyzed using the log-rank test for univariate analysis and the Cox proportional hazards model for multivariate analysis. RESULTS: The overall median survival from diagnosis of pulmonary metastasis for all patients was 15 months. The 3-year actuarial survival rate was 25%. The ability to resect all metastatic disease completely was the most important prognostic factor for survival. Patients treated with complete resection had a median survival of 33 months and a 3-year actuarial survival rate of 46%. For patients treated with nonoperative therapy, the median survival was 11 months. A disease-free interval of more than 12 months before the development of metastases was also a favorable prognostic factor. Unfavorable factors included the histologic variants of liposarcoma and malignant peripheral nerve tumors and patient age older than 50 years at the time of treatment of metastasis. CONCLUSIONS: Resection of metastatic disease is the single most important factor that determines outcome in these patients. Long-term survival is possible in selected patients, particularly when recurrent pulmonary disease is resected. Surgical excision should remain the treatment of choice for metastases of soft tissue sarcoma to the lung.  (+info)

The enigma of desmoid tumors. (8/1415)

OBJECTIVE: To analyze patients with recurrent extremity desmoids, in whom the surgical therapeutic option was either major amputation or observation. SUMMARY BACKGROUND DATA: The biology and natural history of desmoid tumors are an enigma. These tumors invade surrounding structures and recur locally but do not metastasize. The morbidity of treating these tumors in the context of their relatively benign biology is uncertain. METHODS: Between July 1982 and June 1998, the authors treated and prospectively followed 206 patients with extremity desmoid tumors. All patients underwent standardized surgical resection, the surgical goal always being complete resection with negative margins. When tumors recurred, they were evaluated for reresection. Amputation was considered when resection was not possible because of neurovascular or major bone involvement, or in the presence of a functionless, painful extremity. RESULTS: During this period, 22 patients had disease that was not resectable without amputation. This was out of a total of 115 patients with primary disease and 91 patients with recurrent disease. All recurrences were local; in no patient did metastasis develop. In this group of 22 patients with unresectable disease, 7 underwent amputation and 15 did not. These 15 patients were followed, alive with disease, having no surgical resection. Four patients received systemic treatment with tamoxifen and nonsteroidal antiinflammatories, three received systemic cytotoxic chemotherapy, and two received both tamoxifen and chemotherapy. Six patients received no systemic treatment. The range of follow-up was 25 to 92 months. In all patients, there was no or insignificant tumor progression; in three patients who underwent observation alone, there was some regression of tumor. During follow-up, no patient has required subsequent amputation, and no patient has died from disease. CONCLUSIONS: In desmoid tumors, aggressive attempts at achieving negative resection margins may result in unnecessary morbidity. Function- and structure-preserving procedures should be the primary goal. In select patients, whose only option is amputation, it may be prudent to observe them with their limb and tumor intact.  (+info)

Soft tissue neoplasms refer to abnormal growths or tumors that develop in the soft tissues of the body. Soft tissues include muscles, tendons, ligaments, fascia, nerves, blood vessels, fat, and synovial membranes (the thin layer of cells that line joints and tendons). Neoplasms can be benign (non-cancerous) or malignant (cancerous), and their behavior and potential for spread depend on the specific type of neoplasm.

Benign soft tissue neoplasms are typically slow-growing, well-circumscribed, and rarely spread to other parts of the body. They can often be removed surgically with a low risk of recurrence. Examples of benign soft tissue neoplasms include lipomas (fat tumors), schwannomas (nerve sheath tumors), and hemangiomas (blood vessel tumors).

Malignant soft tissue neoplasms, on the other hand, can grow rapidly, invade surrounding tissues, and may metastasize (spread) to distant parts of the body. They are often more difficult to treat than benign neoplasms and require a multidisciplinary approach, including surgery, radiation therapy, and chemotherapy. Examples of malignant soft tissue neoplasms include sarcomas, such as rhabdomyosarcoma (arising from skeletal muscle), leiomyosarcoma (arising from smooth muscle), and angiosarcoma (arising from blood vessels).

It is important to note that soft tissue neoplasms can occur in any part of the body, and their diagnosis and treatment require a thorough evaluation by a healthcare professional with expertise in this area.

Neoplasms of connective and soft tissue are abnormal growths or tumors that develop in the body's supportive tissues, such as cartilage, tendons, ligaments, fascia, and fat. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign connective and soft tissue neoplasms include:
- Lipomas: slow-growing, fatty tumors that develop under the skin.
- Fibromas: firm, benign tumors that develop in connective tissue such as tendons or ligaments.
- Nevi (plural of nevus): benign growths made up of cells called melanocytes, which produce pigment.

Malignant connective and soft tissue neoplasms include:
- Sarcomas: a type of cancer that develops in the body's supportive tissues such as muscle, bone, fat, cartilage, or blood vessels. There are many different types of sarcomas, including liposarcoma (fatty tissue), rhabdomyosarcoma (muscle), and osteosarcoma (bone).
- Desmoid tumors: a rare type of benign tumor that can become aggressive and invade surrounding tissues. While not considered cancerous, desmoid tumors can cause significant morbidity due to their tendency to grow and infiltrate nearby structures.

Connective and soft tissue neoplasms can present with various symptoms depending on their location and size. Treatment options include surgery, radiation therapy, chemotherapy, or a combination of these modalities. Regular follow-up care is essential to monitor for recurrence or metastasis (spread) of the tumor.

Neoplasms of bone tissue refer to abnormal and excessive growths or tumors that develop in the bone. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms, such as osteochondromas and enchondromas, are slow-growing and rarely spread to other parts of the body. However, they may cause problems if they grow too large and compress surrounding tissues. Malignant neoplasms, on the other hand, can invade and destroy nearby bone tissue and may metastasize (spread) to other organs in the body. Examples of malignant bone tumors include osteosarcoma, chondrosarcoma, and Ewing sarcoma. Treatment for bone neoplasms depends on several factors, including the type, size, location, and stage of the tumor, as well as the patient's age and overall health.

A neoplasm of gonadal tissue refers to an abnormal growth or tumor that develops in the reproductive organs, specifically the ovaries in women and the testes in men. These tumors can be benign (non-cancerous) or malignant (cancerous), and their growth can interfere with the normal function of the gonads.

Gonadal tissue neoplasms can have various causes, including genetic mutations, environmental factors, and hormonal imbalances. The symptoms of these tumors may vary depending on their size, location, and type, but they can include pelvic pain, bloating, abnormal menstruation, or a palpable mass in the affected area.

It is essential to diagnose and treat gonadal tissue neoplasms as early as possible to prevent complications such as infertility, metastasis, or death. Diagnostic procedures may include imaging tests, blood tests, and biopsies, while treatment options may include surgery, radiation therapy, chemotherapy, or hormone therapy.

Neoplasms in adipose tissue refer to abnormal and excessive growths of cells that form tumors within the fatty connective tissue. These neoplasms can be benign or malignant (cancerous). Benign neoplasms, such as lipomas, are slow-growing and typically do not spread to other parts of the body. Malignant neoplasms, on the other hand, are cancerous and can invade surrounding tissues and spread to distant sites in the body (metastasis). An example of a malignant neoplasm in adipose tissue is liposarcoma. It's important to note that while some neoplasms may not cause any symptoms, others can cause pain, swelling or other uncomfortable sensations, and therefore should be evaluated by a medical professional for proper diagnosis and treatment.

Neoplasms of nerve tissue are abnormal growths or tumors that originate in the nervous system, including the brain, spinal cord, and peripheral nerves. These neoplasms can be benign or malignant (cancerous) and can cause a variety of symptoms depending on their location and size.

Benign nerve tissue neoplasms are typically slow-growing and do not spread to other parts of the body. Examples include schwannomas, neurofibromas, and meningiomas. These tumors arise from the supporting cells of the nervous system, such as Schwann cells, which produce the myelin sheath that insulates nerve fibers.

Malignant nerve tissue neoplasms, on the other hand, are cancerous and can invade nearby tissues and spread to other parts of the body. These tumors are less common than benign neoplasms and can be difficult to treat. Examples include glioblastoma multiforme, a highly aggressive brain cancer, and malignant peripheral nerve sheath tumors, which arise from the cells that surround peripheral nerves.

Symptoms of nerve tissue neoplasms can vary widely depending on their location and size. Some common symptoms include headaches, seizures, weakness or numbness in the limbs, difficulty with coordination or balance, and changes in vision, hearing, or speech. Treatment options for nerve tissue neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Neoplasms of connective tissue are abnormal growths or tumors that develop from the cells that form the body's supportive framework, including bones, cartilage, tendons, ligaments, and other connective tissues. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can cause various symptoms depending on their location and size.

There are several types of connective tissue neoplasms, including:

1. Fibroma: A benign tumor that arises from fibrous connective tissue.
2. Fibrosarcoma: A malignant tumor that develops from fibrous connective tissue.
3. Lipoma: A benign tumor that arises from fat cells.
4. Liposarcoma: A malignant tumor that develops from fat cells.
5. Chondroma: A benign tumor that arises from cartilage.
6. Chondrosarcoma: A malignant tumor that develops from cartilage.
7. Osteoma: A benign tumor that arises from bone.
8. Osteosarcoma: A malignant tumor that develops from bone.
9. Giant cell tumors: Benign or malignant tumors that contain many giant cells, which are large, multinucleated cells.
10. Synovial sarcoma: A malignant tumor that arises from the synovial tissue that lines joints and tendons.

Connective tissue neoplasms can cause various symptoms depending on their location and size. For example, a benign lipoma may cause a painless lump under the skin, while a malignant osteosarcoma may cause bone pain, swelling, and fractures. Treatment options for connective tissue neoplasms include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

A neoplasm of vascular tissue is an abnormal growth or mass of cells in the blood vessels or lymphatic vessels. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms, such as hemangiomas and lymphangiomas, are typically not harmful and may not require treatment. However, they can cause symptoms if they grow large enough to press on nearby organs or tissues. Malignant neoplasms, such as angiosarcomas, are cancerous and can invade and destroy surrounding tissue, as well as spread (metastasize) to other parts of the body. Treatment for vascular tissue neoplasms depends on the type, size, location, and stage of the growth, and may include surgery, radiation therapy, chemotherapy, or a combination of these.

Neoplasms of fibrous tissue are abnormal growths or tumors that originate from fibroblasts, the cells responsible for producing connective tissue in the body. These neoplasms can be benign or malignant (cancerous). Benign fibrous neoplasms include fibromas and fibrohistiocytic tumors, while malignant fibrous neoplasms are called fibrosarcomas. Fibrosarcomas are aggressive tumors that invade surrounding tissues and can metastasize (spread) to other parts of the body.

Fibrous tissue neoplasms can occur in any part of the body, but they are most commonly found in the soft tissues such as muscles, tendons, and ligaments. They can also develop in bones, where they are called osteosarcomas. Symptoms of fibrous tissue neoplasms depend on their size and location, but may include a painless mass or swelling, limited mobility, or pain if the tumor is pressing on nerves or blood vessels.

Diagnosis of fibrous tissue neoplasms typically involves imaging tests such as X-rays, CT scans, or MRI scans, followed by a biopsy to confirm the type and grade of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up care is important to monitor for recurrence or metastasis.

Sarcoma is a type of cancer that develops from certain types of connective tissue (such as muscle, fat, fibrous tissue, blood vessels, or nerves) found throughout the body. It can occur in any part of the body, but it most commonly occurs in the arms, legs, chest, and abdomen.

Sarcomas are classified into two main groups: bone sarcomas and soft tissue sarcomas. Bone sarcomas develop in the bones, while soft tissue sarcomas develop in the soft tissues of the body, such as muscles, tendons, ligaments, fat, blood vessels, and nerves.

Sarcomas can be further classified into many subtypes based on their specific characteristics, such as the type of tissue they originate from, their genetic makeup, and their appearance under a microscope. The different subtypes of sarcoma have varying symptoms, prognoses, and treatment options.

Overall, sarcomas are relatively rare cancers, accounting for less than 1% of all cancer diagnoses in the United States each year. However, they can be aggressive and may require intensive treatment, such as surgery, radiation therapy, and chemotherapy.

Neoplasms in muscle tissue refer to abnormal and excessive growths of muscle cells that can be benign or malignant. These growths can arise from any of the three types of muscle tissue: skeletal, cardiac, or smooth muscle. Neoplasms in muscle tissue are classified based on their origin, behavior, and histological features.

Benign neoplasms in muscle tissue include leiomyomas (smooth muscle), rhabdomyomas (skeletal muscle), and myxomas (cardiac muscle). These tumors are usually slow-growing and do not invade surrounding tissues or spread to other parts of the body.

Malignant neoplasms in muscle tissue, also known as sarcomas, include leiomyosarcoma (smooth muscle), rhabdomyosarcoma (skeletal muscle), and angiosarcoma (cardiac muscle). These tumors are aggressive, invasive, and have the potential to metastasize to other parts of the body.

Symptoms of neoplasms in muscle tissue depend on their location, size, and type. They may include a painless or painful mass, weakness, fatigue, weight loss, and difficulty swallowing or breathing. Treatment options for neoplasms in muscle tissue include surgery, radiation therapy, chemotherapy, and targeted therapy. The choice of treatment depends on the type, stage, location, and patient's overall health condition.

Soft tissue injuries refer to damages that occur in the body's connective tissues, such as ligaments, tendons, and muscles. These injuries can be caused by various events, including accidents, falls, or sports-related impacts. Common soft tissue injuries include sprains, strains, and contusions (bruises).

Sprains occur when the ligaments, which connect bones to each other, are stretched or torn. This usually happens in the joints like ankles, knees, or wrists. Strains, on the other hand, involve injuries to the muscles or tendons, often resulting from overuse or sudden excessive force. Contusions occur when blood vessels within the soft tissues get damaged due to a direct blow or impact, causing bleeding and subsequent bruising in the affected area.

Soft tissue injuries can cause pain, swelling, stiffness, and limited mobility. In some cases, these injuries may require medical treatment, including physical therapy, medication, or even surgery, depending on their severity and location. It is essential to seek proper medical attention for soft tissue injuries to ensure appropriate healing and prevent long-term complications or chronic pain.

Soft tissue infections are medical conditions that involve infection of the soft tissues of the body, which include the skin, muscles, fascia (the connective tissue that surrounds muscles), and tendons. These infections can be caused by various types of bacteria, viruses, fungi, or parasites.

Soft tissue infections can range from mild to severe, depending on the type of organism causing the infection, the extent of tissue involvement, and the patient's overall health status. Some common types of soft tissue infections include:

1. Cellulitis: This is a bacterial infection that affects the skin and underlying tissues. It typically presents as a red, swollen, warm, and painful area on the skin, often accompanied by fever and chills.
2. Abscess: An abscess is a localized collection of pus in the soft tissues, caused by an infection. It can appear as a swollen, tender, and warm lump under the skin, which may be filled with pus.
3. Necrotizing fasciitis: This is a rare but severe soft tissue infection that involves the rapid destruction of fascia and surrounding tissues. It is often caused by a mixture of bacteria and can progress rapidly, leading to shock, organ failure, and even death if not treated promptly.
4. Myositis: This is an inflammation of the muscle tissue, which can be caused by a bacterial or viral infection. Symptoms may include muscle pain, swelling, weakness, and fever.
5. Erysipelas: This is a superficial skin infection that affects the upper layers of the skin and the lymphatic vessels. It typically presents as a raised, red, and painful rash with clear borders.

Treatment for soft tissue infections depends on the type and severity of the infection but may include antibiotics, drainage of pus or abscesses, and surgery in severe cases. Preventive measures such as good hygiene, wound care, and prompt treatment of injuries can help reduce the risk of developing soft tissue infections.

The mouth mucosa refers to the mucous membrane that lines the inside of the mouth, also known as the oral mucosa. It covers the tongue, gums, inner cheeks, palate, and floor of the mouth. This moist tissue is made up of epithelial cells, connective tissue, blood vessels, and nerve endings. Its functions include protecting the underlying tissues from physical trauma, chemical irritation, and microbial infections; aiding in food digestion by producing enzymes; and providing sensory information about taste, temperature, and texture.

The hard palate is the anterior, bony part of the roof of the mouth, forming a vertical partition between the oral and nasal cavities. It is composed of the maxilla and palatine bones, and provides attachment for the muscles of the soft palate, which functions in swallowing, speaking, and breathing. The hard palate also contains taste buds that contribute to our ability to taste food.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

A "cheek" is the fleshy, muscular area of the face that forms the side of the face below the eye and above the jaw. It contains the buccinator muscle, which helps with chewing by moving food to the back teeth for grinding and also assists in speaking and forming facial expressions. The cheek also contains several sensory receptors that allow us to perceive touch, temperature, and pain in this area of the face. Additionally, there is a mucous membrane lining inside the mouth cavity called the buccal mucosa which covers the inner surface of the cheek.

The intestinal mucosa is the innermost layer of the intestines, which comes into direct contact with digested food and microbes. It is a specialized epithelial tissue that plays crucial roles in nutrient absorption, barrier function, and immune defense. The intestinal mucosa is composed of several cell types, including absorptive enterocytes, mucus-secreting goblet cells, hormone-producing enteroendocrine cells, and immune cells such as lymphocytes and macrophages.

The surface of the intestinal mucosa is covered by a single layer of epithelial cells, which are joined together by tight junctions to form a protective barrier against harmful substances and microorganisms. This barrier also allows for the selective absorption of nutrients into the bloodstream. The intestinal mucosa also contains numerous lymphoid follicles, known as Peyer's patches, which are involved in immune surveillance and defense against pathogens.

In addition to its role in absorption and immunity, the intestinal mucosa is also capable of producing hormones that regulate digestion and metabolism. Dysfunction of the intestinal mucosa can lead to various gastrointestinal disorders, such as inflammatory bowel disease, celiac disease, and food allergies.

Epithelium is the tissue that covers the outer surface of the body, lines the internal cavities and organs, and forms various glands. It is composed of one or more layers of tightly packed cells that have a uniform shape and size, and rest on a basement membrane. Epithelial tissues are avascular, meaning they do not contain blood vessels, and are supplied with nutrients by diffusion from the underlying connective tissue.

Epithelial cells perform a variety of functions, including protection, secretion, absorption, excretion, and sensation. They can be classified based on their shape and the number of cell layers they contain. The main types of epithelium are:

1. Squamous epithelium: composed of flat, scalelike cells that fit together like tiles on a roof. It forms the lining of blood vessels, air sacs in the lungs, and the outermost layer of the skin.
2. Cuboidal epithelium: composed of cube-shaped cells with equal height and width. It is found in glands, tubules, and ducts.
3. Columnar epithelium: composed of tall, rectangular cells that are taller than they are wide. It lines the respiratory, digestive, and reproductive tracts.
4. Pseudostratified epithelium: appears stratified or layered but is actually made up of a single layer of cells that vary in height. The nuclei of these cells appear at different levels, giving the tissue a stratified appearance. It lines the respiratory and reproductive tracts.
5. Transitional epithelium: composed of several layers of cells that can stretch and change shape to accommodate changes in volume. It is found in the urinary bladder and ureters.

Epithelial tissue provides a barrier between the internal and external environments, protecting the body from physical, chemical, and biological damage. It also plays a crucial role in maintaining homeostasis by regulating the exchange of substances between the body and its environment.

Gingivoplasty is a surgical procedure in dentistry that involves the reshaping or contouring of the gingiva (gums). This procedure is typically performed for aesthetic purposes, to improve the appearance of gums that are uneven or have an irregular shape. It can also be done to remove excess gum tissue that may be covering too much of a tooth, making it appear shorter than the other teeth.

Gingivoplasty is often recommended as a part of periodontal treatment to ensure the proper fit and function of dental restorations or to manage and prevent gum disease. The procedure involves removing and reshaping the gingival tissue to create a more aesthetically pleasing and healthy gum line.

It's important to note that while gingivoplasty can improve the appearance of the gums, it does not address any underlying issues related to gum disease or bone loss. Additional periodontal treatments may be necessary to address these concerns.

This may cause rigid tissues and difficulty opening the mouth. Benign soft tissue neoplasms 1. Peripheral nerve sheath tumours ... It consists of loose connective tissue within the connective tissue papillae, along with blood vessels and nerve tissue. The ... Histologically, an excess amount of keratin is noted on the surface of the tissue, and the tissue has all the layers of an ... If present, the submucosa usually contains loose connective tissue and may also contain adipose tissue or salivary glands, as ...
Wick MR, Hornick JL (2011). "Immunohistology of Soft Tissue and Osseous Neoplasms". Diagnostic Immunohistochemistry. Elsevier. ... Myoglobin (symbol Mb or MB) is an iron- and oxygen-binding protein found in the cardiac and skeletal muscle tissue of ... Myoglobin is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations of myoglobin. The ...
Li F.P.; Fraumeni J.F. (October 1969). "Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?". Ann. ... This is followed by soft-tissue sarcomas (20%), bone sarcoma (15%), and brain tumors-especially glioblastomas-(13%). Other ... soft tissue sarcoma, osteosarcoma, CNS tumor, adrenocortical carcinoma) before age 46 years, and at least one first- or second- ... The difference may be due to much smaller breast tissue in males and increased estrogen levels in females. The risks of sarcoma ...
PMID 23426075 Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the ... Many cutaneous neoplasms occur in the setting of systemic syndromes. List of cutaneous conditions List of contact allergens ...
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... Eighty-two percent of their LGMS tumors were located in soft tissues (28.2% in mucous membranes, 21.8% in muscle, 19.2% in skin ... Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". ... Choi JH, Ro JY (January 2021). "The 2020 WHO Classification of Tumors of Soft Tissue: Selected Changes and New Entities". ...
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... is a rare type of soft-tissue tumor marked by painless nodules in the dermis (the inner layer of the two main layers of tissue ... Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". ... GCF tumor tissues consist of bland spindle-shaped or stellate-shaped cells interspersed among multinucleated giant cells. GCF ...
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ...
FMTs are a heterogeneous group of soft tissue neoplasms (i.e. abnormal and excessive tissue growths). The World Health ... Connective and soft tissue neoplasms, Benign neoplasms, Cancer). ... Angiofibroma of soft tissue, also termed angiofibroma NOS (NOS ... Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... also termed myofibroblastoma of soft tissues, is a mammary-type myofibroblastoma that occurs in non-mammary tissues and may be ...
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... and several conditional mutants that allow for tissue-specific or temporal ablation of gene function. For more information see ...
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... Connective and soft tissue neoplasms, Benign neoplasms). ... or deep soft tissues of the back and chest wall and ~5 years ... Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". ... Coffin CM, Davis JL, Borinstein SC (January 2014). "Syndrome-associated soft tissue tumours". Histopathology. 64 (1): 68-87. ...
Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome? Ann Intern Med 1969:71:747-752. Li FP, Fraumeni ... Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990:250: 1233-1238. ( ...
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... Desmoid tumors are fibrous tumors that usually occur in the tissue covering the intestines and may be provoked by surgery to ... The incidence of mammary desmoid tumors is less than 0.2% of primary breast neoplasms. In Gardner's syndrome, the incidence ... List of cutaneous conditions List of dental abnormalities associated with cutaneous conditions List of cutaneous neoplasms ...
v t e (All stub articles, Neoplasm stubs, Connective and soft tissue neoplasms). ... Spindle cell rhabdomyosarcoma typically occurs in young males and most commonly occurs in paratesticular soft tissue, followed ...
Soft tissue sarcomas are rare neoplasms with over 150 different histological subtypes or forms. Liposarcomas arise from the ... These tumors are usually localized in deep soft tissues with only 25% of cases presenting in subcutaneous tissues. Rare cases ... MPL tumors present as deep soft-tissue masses that are often located in the mediastinum and, less often, the extremities, head ... Liposarcomas are the most common subtype of soft tissue sarcomas, accounting for at least 20% of all sarcomas in adults. ...
Connective and soft tissue neoplasms). ... Sarcomatous components may also mimic extrauterine tissues (e.g ... connective tissue) components. It is divided into two types, homologous (in which the sarcomatous component is made of tissues ... found in the uterus such as endometrial, fibrous and/or smooth muscle tissues) and a heterologous type (made up of tissues not ... in which the different types of tissues are believed to either develop separately and join into a single mass (the "collision" ...
EMC shows the smallest morphological variation between the tumors among all myxoid soft tissue neoplasms. The myxoid matrix has ... Extraskeletal myxoid chondrosarcoma (EMC) is a rare low-grade malignant mesenchymal neoplasm of the soft tissues, that differs ... "Molecular Pathology of Bone and Soft Tissue Tumors". Cell and Tissue Based Molecular Pathology. Elsevier. pp. 325-359. doi: ... EMC is rare and accounts for less than 3% of soft tissue tumors. It mainly affects adults with an average age of about 54 years ...
Connective and soft tissue neoplasms). ... "The 2020 WHO Classification of Soft Tissue Tumours: news and ... Nuchal-type fibroma is a rare benign proliferation involving the dermis and subcutaneous tissues, that is a collection of dense ... ISBN 978-1-931884-61-7. (Articles with short description, Short description matches Wikidata, Benign neoplasms, ...
Articles with short description, Short description matches Wikidata, Connective and soft tissue neoplasms, Benign neoplasms). ... are rare benign soft tissue lesions (i.e. a damaged or unspecified abnormal change in a tissue) that increase in size over ... Rosenberg AE (April 2008). "Pseudosarcomas of soft tissue". Archives of Pathology & Laboratory Medicine. 132 (4): 579-86. doi: ... PF/PM lesions have been regarded as a tissue's self-limiting reaction to an injury or unidentified insult rather than an ...
Articles with short description, Short description is different from Wikidata, Connective and soft tissue neoplasms, Sarcoma). ... As the most common form of soft tissue sarcoma, RMS affects around 4.5 people per million individuals under the age of 20 in ... Embryonal rhabdomyosarcoma can develop in soft tissues throughout the body; however, it is commonly found in the "head and neck ... It is the most common soft tissue sarcoma occurring in children. Embryonal rhabdomyosarcoma is also known as PAX-fusion ...
Connective and soft tissue neoplasms). ... soft tissue, and internal organs in young children caused by ... they can also extend into the subcutaneous tissue and/or muscle tissue. The second form of infantile myofibromatosis is called ... Desmoid tumors occur in any connective tissue in the body but are often found in the abdomen, shoulders, arms, and thighs. ... In a case study in a 15-month-old diagnosed with diffuse infantile fibromatosis, the lesion tissue extracted from the infant's ...
Connective and soft tissue neoplasms, Benign neoplasms). ... "Fat-containing soft-tissue masses in children". Pediatric ... Navarro OM (October 2020). "Pearls and Pitfalls in the Imaging of Soft-Tissue Masses in Children". Seminars in Ultrasound, CT, ... Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". ... On gross pathological examination, FHI tumors are soft, poorly demarcated, fibro-fatty masses located in subcutaneous tissues. ...
These findings can differentiate LGFMS from various spindle-shaped cell and myxoid neoplasms including benign soft tissue ... LGFMS are soft tissue tumors of the mesenchyme-derived connective tissues; on microscopic examination, they are found to be ... Porrino J, Al-Dasuqi K, Irshaid L, Wang A, Kani K, Haims A, Maloney E (June 2021). "Update of pediatric soft tissue tumors with ... Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". ...
ISBN 0-7216-2921-0. v t e (Dermal and subcutaneous growths, Connective and soft tissue neoplasms, All stub articles, Dermal and ...
v t e (Dermal and subcutaneous growths, Connective and soft tissue neoplasms, All stub articles, Dermal and subcutaneous growth ... The mass is made of fibro-fatty tissue that begins encroaches on a nerve. Surgery is often needed to relieve pressure. Some ... However, if a biopsy is taken, it will show an abundance of mature fat cells surrounded by fibrous connective tissue. Neural ... Neural fibrolipoma is an overgrowth of fibro-fatty tissue along a nerve trunk that often leads to nerve compression. These only ...
Connective and soft tissue neoplasms, Cancer). ... soft tissues (9.1%), upper limb and shoulder areas (7.5%), ... Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". ... Agaimy A (January 2020). "What is new in epithelioid soft tissue tumors?". Virchows Archiv. 476 (1): 81-96. doi:10.1007/s00428- ... Sclerosing epithelioid fibrosarcoma (SEF) is a very rare malignant tumor of soft tissues that on microscopic examination ...
v t e (Dermal and subcutaneous growths, Connective and soft tissue neoplasms, All stub articles, Dermal and subcutaneous growth ...
Tissues (biology), Connective and soft tissue neoplasms). ... A connective tissue neoplasm or connective tissue tumor is a ... neoplasm arising from the tissues of the connective tissue. (Not all tumors in the connective tissue are of the connective ... v t e (Articles with short description, Short description is different from Wikidata, All stub articles, Neoplasm stubs, ... tissue.) Zelger, Bernhard (2002). "Connective tissue tumors". Recent Results in Cancer Research. Fortschritte der ...
Benign neoplasms, Connective and soft tissue neoplasms). ... the excision biopsy can collect a tissue sample from the tumor ... It is the most common extratesticular neoplasm after lipoma, and accounts for 30% of these masses. On the other hand, ... and negative in other benign mesothelial tissues and mesothelioma). Adenomatoid tumors of the female and male genital tract are ... Although adenomatoid tumors are not known to infiltrate surrounding tissues, it is possible that there are multiple adenomatoid ...
These tumors, on occasion, may appear similar to neoplasms of renal (relating to the kidneys) origin or other soft tissue ... Malignant granular cell tumor of soft tissue: diagnostic criteria and clinicopathologic correlation. Am J Surg Pathol. Jul 1998 ... Granular cell tumors are derived from neural tissue, as can be demonstrated by immunohistochemistry and ultrastructural ... neoplasms. The primary method for treatment is surgical, not medical. Radiation and chemotherapy are not needed for benign ...
Connective and soft tissue neoplasms, Benign neoplasms). ... soft tissue nodules or masses in the vulva-vaginal and inguinal ... Cellular angiofibroma (CAF) is a rare, benign tumor of superficial soft tissues that was first described by M. R. Nucci et al. ... Libbrecht S, Van Dorpe J, Creytens D (March 2021). "The Rapidly Expanding Group of RB1-Deleted Soft Tissue Tumors: An Updated ... Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". ...
Soft tissue neoplasms - cite! Soft tissue neoplasms (message) Soft tissue neoplasms - participate! ... Retrieved from "https://confocalpedia.org/w/index.php?title=Soft_tissue_neoplasms&oldid=954" ...
Study Keyword: Soft Tissue Neoplasms. This is a study of perioperative pembrolizumab or enfortumab vedotin in combination with ... Study Keyword: Soft Tissue Neoplasms. Perioperative Pembrolizumab Plus Cystectomy or Perioperative Pembrolizumab Plus ...
This may cause rigid tissues and difficulty opening the mouth. Benign soft tissue neoplasms 1. Peripheral nerve sheath tumours ... It consists of loose connective tissue within the connective tissue papillae, along with blood vessels and nerve tissue. The ... Histologically, an excess amount of keratin is noted on the surface of the tissue, and the tissue has all the layers of an ... If present, the submucosa usually contains loose connective tissue and may also contain adipose tissue or salivary glands, as ...
... of bone and soft tissue with the translocation t(11;22) (q24;q12). Ten cases were primary in bone, and one was of extraskeletal ... Soft Tissue Neoplasms / genetics* * Soft Tissue Neoplasms / pathology * Translocation, Genetic* Substances * Antibodies, ... Our results support the hypothesis that SRCT of bone of soft tissue with the t(11;22) form a single biologic entity displaying ... Hence, five of 11 SRCT of bone or soft tissue with the t(11;22) showed morphologic and/or immunohistochemical evidence of ...
Lipoma; Mouth; Soft Tissue Neoplasms Share and Cite: Caldeira, P. , Bernardes, V. , Miranda, A. , Telles, D. , Batista, R. , ... Bandéca, M.C., De Pádua, J.M., Nadalin, M.R., Ozório, J.E., Silva-Sousa, Y.T. and Da Cruz, P.D.E. (2007) Oral soft tissue ... 2002) Pathology and genetics of tumours of soft tissue and bone. World Health Organization Classification of Tumours, IARC ... tive tissue. Cells were immunopositive for S100 pro- tein and CD34 (one case), with low mitotic activity (Ki-67). The final ...
Malignant neoplasm of colon. C47.0 - C47.9, C49.0 - C49.9. Malignant neoplasm of connective tissue and other soft tissue [ ... Malignant neoplasm of connective tissue and other soft tissue [leiomyosarcoma]. C78.7. Secondary malignant neoplasm of liver ... Malignant neoplasm of the liver, not specified as primary or secondary. C78.7. Secondary malignant neoplasm of liver and ... Malignant neoplasm of the liver and intrahepatic bile ducts [unresectable]. C25.0 - C25.9. Malignant neoplasm of pancreas [ ...
Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?. Ann Intern Med. 1969 Oct. 71 (4):747-52. [QxMD ... An increased number of skin and soft-tissue abscesses caused by community-acquired methicillin-resistant S aureus (MRSA) have ... 6] The literature suggests that drainage alone, without adjunctive antibiotics, may be effective in skin and soft-tissue ... Management and outcome of children with skin and soft tissue abscesses caused by community-acquired methicillin-resistant ...
Leiomyomas are benign soft tissue neoplasms that arise from smooth muscle; they were first described by Virchow in 1854. The ... Leiomyomas are benign soft-tissue neoplasms that arise from smooth muscle; they were first described by Virchow in 1854 as " ... Cutaneous leiomyomas are benign soft-tissue neoplasms that arise from smooth muscle (arrector pili). The arrector pili muscle ... Woertler K. Soft tissue masses in the foot and ankle: characteristics on MR Imaging. Semin Musculoskelet Radiol. 2005 Sep. 9(3 ...
al., World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002). ... Perivascular Epithelioid Cell Neoplasms: A family of mesenchymal tumors composed of histologically and immunohistochemically ... Neoplasms: 649836*Neoplasms by Histologic Type: 1*Connective and Soft Tissue Neoplasms*Perivascular Epithelioid Cell Neoplasms ... al., World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002). ...
"Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck". Head and Neck Pathology. 14 (1): ... List of cutaneous neoplasms associated with systemic syndromes. References[edit]. .mw-parser-output .reflist{font-size:90%; ... Desmoid tumors are fibrous tumors that usually occur in the tissue covering the intestines and may be provoked by surgery to ... The incidence of mammary desmoid tumors is less than 0.2% of primary breast neoplasms. In Gardners syndrome, the incidence ...
Cytopathology and surgical pathology; neoplasms of bone and soft tissue. Phone: 984-974-9147. Email ... Cytopatholgy including fine needle aspiration, and diagnostic surgical pathology with focus on bone and soft tissue, and ...
Immunohistochemical staining of neoplasms was performed from biopsies samples. The pathological diagnosis was extranodal ... Head computed tomography (CT) and magnetic resonance imaging (MRI) scans revealed soft-tissue density neoplasms that occupied ... CT showed soft-tissue density neoplasms filled with sphenoidal sinus, which is hard to differentiate with sphenoid sinusitis ... Head computed tomography (CT) and magnetic resonance imaging (MRI) scans revealed soft-tissue density neoplasms that occupied ...
Categories: Neoplasms, Connective and Soft Tissue Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Soft Tissue Neoplasm. * Wounds. Search ADVERTISEMENT. Contact. 9312 Old Georgetown Road. Bethesda, MD 20814-1621. 301-581-9200 ...
Soft tissue myoepithelioma is a rare neoplasm composed of myoepithelial cells. We describe the cytologic features of a soft ... Like its soft tissue counterpart, uterine IMT frequently expresses ALK and harbors ALK genetic rearrangements. The aim of this ... Inflammatory myofibroblastic tumor (IMT) is a genetically heterogenous tumor of the viscera and soft tissues, with multiple ... The technique works well with a variety of starting materials from fresh or formalin-fixed tissues, cell lysates or biological ...
A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. ... Neoplasms: 649836*Neoplasms by Histologic Type: 1*Connective and Soft Tissue Neoplasms*Sarcoma: 14738*Osteosarcoma: 9412 ... Sarcoma (Soft Tissue Sarcoma). Subscribe to New Research on Sarcoma A connective tissue neoplasm formed by proliferation of ... Soft Tissue Sarcoma; Sarcomas; Soft Tissue Sarcomas; Spindle Cell Sarcoma; Epithelioid Sarcoma; Epithelioid Sarcomas; Sarcomas ...
This approach allowed adequate resection of the neoplasm with minimal damage to the adjacent tissues, thus reducing post- ... These neoplasms are mainly treated surgically and an accurate histological examination is mandatory for a precise diagnosis. We ... Several neoplasms of the adipose tissue can involve the soft tissues of the head and neck region. ... Several neoplasms of the adipose tissue can involve the soft tissues of the head and neck region. These neoplasms are mainly ...
1969) Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome? Ann Intern Med 71:747-752. ... 1990) Melanoma and soft tissue sarcoma in seven patients. Cancer 66:2432-2434. ... including soft tissue sarcomas, osteosarcomas, adrenocortical carcinomas, brain tumours, breast carcinomas, and leukaemia,1-3 ... 1990) Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238. ...
Neoplasms, Connective and Soft Tissue. Neoplasms by Histologic Type. Neoplasms. Osteosarcoma. Neoplasms, Bone Tissue. Neoplasms ... MedlinePlus related topics: Safety Soft Tissue Sarcoma Genetic and Rare Diseases Information Center resources: Soft Tissue ...
Neoplasms, Connective Tissue. Neoplasms, Connective and Soft Tissue. Neoplasms by Histologic Type. Neoplasms. Gastrointestinal ...
... a rare neoplasm that poses a diagnostic dilemma in the differential diagnosis of neck masses and portends poor prognosis. We ... Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue neoplasm with a poor prognosis. It can occur in ... S. Weiss and F. Enzinger, "Malignant tumors of peripheral nerves," in Enzinger and Weisss Soft Tissue Tumors, S. Weiss and R. ... of soft tissue sarcomas [1-4]. MPNST occurs in about 2-5% of patients with NF-1, compared with a prevalence of 0.001% in the ...
Neoplasms, Soft Tissue. Disclaimer: We update this information regularly. However, what you read today may not be completely up ... Lymphedema Melanoma Merkel Cell Carcinoma Mesothelioma Multiple Myeloma Myelodysplastic Syndrome Myeloproliferative Neoplasms ...
Granular cell tumor (GCT) is a rare soft tissue neoplasm of Schwann cell origin. Most cases occur in adults; however, the ... GCT is usually a slow-growing, painless tumor involving the skin and soft tissues that is mostly located in the head and neck ... Pediatric Granular Cell Tumor of the Breast: An uncommon neoplasm in an uncommon site and age group Authors. * Pakesh Baishya ... This paper presents a 3-year-old girl who presented with a soft to firm, ill-defined swelling on the right breast with painful ...
Malignant neoplasm of bone [osteosarcoma]. C49.0 - C49.9. Malignant neoplasm of connective and soft tissue [soft tissue sarcoma ... Radiotherapy (RT) of soft-tissue plasmacytoma is the further treatment choice and resulted in a high rate of local control and ... Soft Tissue Sarcoma. Nair and colleagues (2017) noted that selinexor, a small molecule that inhibits nuclear export protein ... SBP, SEP and MSP are rare clinical entities, characterised by a monoclonal plasma cell infiltrate in bone or soft tissue. ...
Soft Tissue Neoplasms/pathology. ... features were noted and diagnosis of a spindle cell neoplasm ...
Desmoid tumors are soft-tissue neoplasms strictly driven by Wnt signaling network hyperactivation. Despite this clearly defined ... Tissue-Specific Gene Inactivation in Xenopus laevis: Knockout of lhx1 in the Kidney with CRISPR/Cas9. 2018, Pubmed , Xenbase ... Method for Picrosirius Red-Polarization Detection of Collagen Fibers in Tissue Sections. 2018, Pubmed Rudolf, β-Catenin ... are likely and do not deviate from what is predicted by InDelphi and experimentally sampled in heart tissue. Given the adam12 ...
Introduction: Gastrointestinal schwannomas are rare benign neoplasms that are distinctively unique when compared to soft-tissue ... Gastric schwannoma represent only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms. Colonic and ... The outcome after surgery is excellent as these neoplasms are generally benign in nature. ... and central nervous system mesenchymal neoplasms. We present a case of a gastric schwannoma causing severe reflux treated ...
Connective and Soft Tissue [C04.557.450]. *Neoplasms, Connective Tissue [C04.557.450.565]. *Neoplasms, Bone Tissue [C04.557. ...
Synovial sarcoma (SS) accounts for 5%-10% of all soft tissue sarcomas. It is a well-defined soft tissue neoplasm with biphasic ... Low-grade fibromyxoid sarcoma (LGFMS) is a bland spindle cell neoplasm that typically arises in the deep soft tissues of the ... Synovial sarcoma is a ubiquitous neoplasm predominantly affecting soft tissues of young adults of any gender; few cases have ... a rare fibroblastic neoplasm that most commonly arises in the deep soft tissues of the lower extremities, limb girdles or trunk ...
  • Clinical, cytogenetic, histopathologic, and immunohistochemical data were obtained in a series of 11 small round cell tumors (SRCT) of bone and soft tissue with the translocation t(11;22) (q24;q12). (nih.gov)
  • World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002). (curehunter.com)
  • Desmoid tumors are fibrous tumors that usually occur in the tissue covering the intestines and may be provoked by surgery to remove the colon. (wikipedia.org)
  • Desmoid tumors are soft- tissue neoplasms strictly driven by Wnt signaling network hyperactivation. (xenbase.org)
  • Gastric schwannoma represent only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms. (sages.org)
  • Desmoid tumors are cytologically bland fibrous neoplasms originating from the musculoaponeurotic structures throughout the body. (medscape.com)
  • Desmoid tumors often appear as infiltrative, usually well-differentiated, firm overgrowths of fibrous tissue, and they are locally aggressive. (medscape.com)
  • Benign musculoskeletal neoplasms are one hundred times more common than malignant soft tissue tumors. (drrathresearch.org)
  • Bone and soft tissue tumors (BSTT) constitute a heterogeneous group of neoplasms of mesenchymal and neuroectodermal origin. (avhandlingar.se)
  • The goal of this project is to evaluate the safety and preliminary efficacy of ExAblate magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) surgery in the treatment of soft tissue tumors of the extremities. (stanford.edu)
  • Desmoid tumors are associated with a biallelic APC mutation in the affected tissue. (medscape.com)
  • Soft tissue tumors (STT) constitute a heterogeneous group of neoplasms that clinically run the gamut from totally benign to highly malignant neoplasms. (lu.se)
  • Soft tissue tumors (STT) constitute a heterogeneous group of approximately 100 distinct neoplasms, including more than 50 malignant subtypes, so-called sarcomas. (lu.se)
  • Elevated SMRs were noted for cancers of the stomach, rectum, brain and other central nervous system sites, connective and other soft tissue, as well as for unspecified neoplasms of the nervous system and unspecified anemias. (cdc.gov)
  • The second explanation was more plausible, where neoplastic Schwann cells can transform into rhabdomyoblasts, suggesting the possibility of some mesenchymal tissue derivation from neuroectodermal cells. (hindawi.com)
  • Gastrointestinal schwannomas are rare benign neoplasms that are distinctively unique when compared to soft-tissue and central nervous system mesenchymal neoplasms. (sages.org)
  • Cardiac sarcoma is a rare mesenchymal neoplasm or tumor of the heart that is malignant in nature. (logicalimages.com)
  • Rhabdosarcoma , the most common soft tissue sarcoma is mesenchymal in origin, and affects infants and children up to five years (mostly males). (drrathresearch.org)
  • Rhabdomyoblastic differentiation in a malignant peripheral nerve sheath tumor (MPNST) is termed malignant triton tumor (MTT), a rare neoplasm that poses a diagnostic dilemma in the differential diagnosis of neck masses and portends poor prognosis. (hindawi.com)
  • Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue neoplasm with a poor prognosis. (hindawi.com)
  • Granular cell tumor (GCT) is a rare soft tissue neoplasm of Schwann cell origin. (usp.br)
  • GCT is usually a slow-growing, painless tumor involving the skin and soft tissues that is mostly located in the head and neck region, especially the tongue. (usp.br)
  • Epstein-Barr virus-associated smooth muscle tumor is an uncommon neoplasm associated with immunodeficiency. (allenpress.com)
  • Epstein-Barr virus (EBV)-associated smooth muscle tumor (SMT) is an uncommon neoplasm typically manifesting in immunodeficient individuals. (allenpress.com)
  • Extraskeletal osteosarcoma (EOS) is a malignant tumor of soft tissue origin comprising tumor cells that produce osteoid matrix. (researchsquare.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • Papillary intralymphatic angioendothelioma (Dabska tumor) is a rarely metastasizing lymphatic vascular neoplasm that usually affects children and young adults. (anaisdedermatologia.org.br)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
  • 2002) Pathology and genetics of tumours of soft tissue and bone. (scirp.org)
  • METHODS: Fifty-three paraffin-embedded tissue blocks of colorectal resections and corresponding patient information were retrieved from the archives of the Anatomic and Molecular Pathology Department of Lagos University Teaching Hospital.A 4-micron slide section was obtained from each specimen and immunohistochemistry for COX-2 and HER-2 expression was performed. (bvsalud.org)
  • This paper reviews the clinicopathologic features of this uncommon neoplasm with detailed discussion of the role of Epstein-Barr virus in the pathogenesis. (allenpress.com)
  • Pulmonary carcinoids are well differentiated low to intermediate grade lung neuroendocrine tumours (LNETs), that belong to the group of lung neuroendocrine neoplasms which also include highly aggressive lung neuroendocrine carcinomas (LNECs). (who.int)
  • These data have been combined with previously published LNET data to perform integrative analysis using multi-omics factor analysis (MOFA), resulting in a molecular map of lung neuroendocrine neoplasms for exploration. (who.int)
  • PurposePrevious studies indicate that breast cancer molecular subtypes differ with respect to their dependency on autophagy, but our knowledge of the differential expression and prognostic significance of autophagy-related biomarkers in breast cancer is limited.Methods Immunohistochemistry (IHC) was performed on tissue microarrays from a large popu. (researchgate.net)
  • Synovial sarcoma , a soft tissue cancer that most often occurs around leg or arm joints, has a 50% rate of metastasis. (drrathresearch.org)
  • Tissue examination is necessary to establish the diagnosis. (medscape.com)
  • These neoplasms are mainly treated surgically and an accurate histological examination is mandatory for a precise diagnosis. (springer.com)
  • With a provisional clinical diagnosis of benign neoplasm, the lesion was surgically excised under local anaesthesia, using a diode laser with a 300 μm fibre and operating at 2,5 W. Direct suture of the surgical margins was unnecessary as no bleeding was observed during and following the excision (Fig. 2 ). (springer.com)
  • On histopathological analysis, all the classic features were noted and diagnosis of a spindle cell neoplasm was made without any obscurity. (oldcitypublishing.com)
  • This neoplasm should be considered in the differential diagnosis of vascular dermatoses, allowing early diagnosis and treatment. (anaisdedermatologia.org.br)
  • Further, microscopic examination revealed a spindle cell malignant neoplasm with osteoid matrix. (researchsquare.com)
  • E ditor -The Li-Fraumeni syndrome (LFS) is a rare familial cancer syndrome that predisposes gene carriers to the development of diverse early onset malignancies, including soft tissue sarcomas, osteosarcomas, adrenocortical carcinomas, brain tumours, breast carcinomas, and leukaemia, 1-3 with other cancer types occurring less frequently. (bmj.com)
  • It can occur in association with neurofibromatosis type 1 (NF-1) or sporadically accounting for 5-10% of soft tissue sarcomas [ 1 - 4 ]. (hindawi.com)
  • Ewing-like sarcomas of bone and soft tissues: entities, strategies and outcomes. (emsos.org)
  • and soft tissue sarcomas and carcinosarcomas (SARCOMICS). (who.int)
  • The common causes of unilateral abducens nerve palsy are neoplasm and vascular disease in middle-aged people [ 1 ]. (hindawi.com)
  • A 55-year-old white female with a complex medical history including mixed connective tissue disease and peripheral vascular disease developed a group of red-purple papules on her proximal medial thigh that was followed, five months later, by the development of a large violaceous patch. (thedoctorsdoctor.com)
  • It is a thin loose covering of keratinizing skin with associated underlying eccrine (sweat) and sebaceous glands and a highly vascular stroma without underlying adipose tissue. (medscape.com)
  • As the current literature provides few information on reconstruction-technique-dependent outcomes following surgery for bone and soft tissue neoplasms involving the proximal tibia, the current multicentre retrospective study may allow to draw further conclusions on how to best approach tumours at this specific anatomical location. (emsos.org)
  • Several neoplasms of the adipose tissue can involve the soft tissues of the head and neck region. (springer.com)
  • To further elucidate the natural history and prognosis of this rare neoplasm in the head and neck, we present a case of sporadic MTT arising in the neck with an unusual prognosis. (hindawi.com)
  • The site of EOS is widespread, and it is prevalent in the deep soft tissues of the extremities, specifically in the thigh muscles 1 , 3 . (researchsquare.com)
  • The majority of these cases occur in soft tissues of extremities, and to date less than 40 cases have been described. (anaisdedermatologia.org.br)
  • Microsco- pically, both lesions presented a solid proliferation of mature fat cells intermixed with bundles of connec- tive tissue. (scirp.org)
  • Magnetic resonance imaging is a diagnostic imaging modality that is capable of demonstrating a wide variety of soft-tissue lesions with contrast resolution equal or superior to CT scanning in various parts of the body. (cms.gov)
  • The histological preparations showed an admixture of mature adipose tissue, including variably sized typical adipocytes, embedded within dense collagen fibres (Fig. 3 ), consistent with fibrolipoma. (springer.com)
  • Retroperitoneal neoplasms are more common in familial polyposis coli and Gardner syndrome after abdominal surgery than in other conditions. (medscape.com)
  • The primary aim is to assess mid- to long-term survival of Ewing-like sarcoma patients (both soft tissues and bones). (emsos.org)
  • This Clinical Policy Bulletin addresses treatment approaches for liver and other neoplasms. (aetna.com)
  • At clinical examination, the lesion appeared soft and well separated from the surrounding tissues and was covered by intact mucosa (Fig. 1 ). (springer.com)
  • Genetic analyses have shown that the clinical and biological variation among these neoplasms is reflected in their genotypes. (lu.se)
  • This lesion usually presents as an asymptomatic swelling of soft consistency, mobile on the surrounding tissues. (springer.com)
  • Following magnetic resonance (MR) scan revealed a soft mass smaller than first one in the left maxillofacial and single-photon emission computed tomography/computed tomography (SPECT/CT) scan showed increased focal uptake in the lesion. (researchsquare.com)
  • Hence, five of 11 SRCT of bone or soft tissue with the t(11;22) showed morphologic and/or immunohistochemical evidence of neural differentiation. (nih.gov)
  • Immunohistochemical staining of neoplasms was performed from biopsies samples. (hindawi.com)
  • Materials and methods: We carried out a retrospective hospital-based immunohistochemical study of archival IDC tissue blocks over a four- and half-year period. (bvsalud.org)
  • The lamina propria is a fibrous connective tissue layer that consists of a network of type I and III collagen and elastin fibers in some regions. (wikipedia.org)
  • in the bone marrow (precursor cells, also called stem cells) develop and reproduce excessively or are crowded out by an overgrowth of fibrous tissue. (msdmanuals.com)
  • WGTA was used to generate reports including molecular alterations and site/tissue of origin prediction. (researchgate.net)
  • This approach allowed adequate resection of the neoplasm with minimal damage to the adjacent tissues, thus reducing post-surgical scarring. (springer.com)
  • En-bloc resection has been the most widely used treatment for grade 2-3 CS, whereas for patients with low-grade CS, curettage is safe and effective. (emsos.org)
  • Histologically, an excess amount of keratin is noted on the surface of the tissue, and the tissue has all the layers of an orthokeratinized tissue with its granular and keratin layers. (wikipedia.org)
  • The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)
  • The ICD-10 code range for Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes D37-D48 is medical classification list by the World Health Organization (WHO). (aapc.com)
  • Thus, to check for malignant changes, a baseline biopsy and microscopic study of any whitened tissue may be indicated, especially if in a high-risk cancer category, such with a history of tobacco or alcohol use or are HPV positive. (wikipedia.org)
  • Fibrosarcoma , an aggressive and highly metastatic cancer of the connective tissue, primarily develops in the metaphyses of long tubular bones, and affects both children and adults. (drrathresearch.org)
  • Athelia (ie, absence of nipples) and amastia (ie, absence of breast tissue) may occur bilaterally or unilaterally. (medscape.com)
  • Mastitis neonatorum or infections of the breast tissue may also occur during the newborn period. (medscape.com)
  • Percutaneous ethanol injection (PEI) for liver neoplasms when criteria above are not met. (aetna.com)
  • Liver neoplasms. (lookformedical.com)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. (lookformedical.com)
  • Epstein-Barr virus-associated SMT is an uncommon soft tissue neoplasm affecting both adult and pediatric populations. (allenpress.com)
  • Soft Tissue and Bone Tumours is the third volume in the 5th edition of the WHO series on the classification of human tumours. (who.int)
  • This volume will be of particular interest to pathologists, oncologists, surgeons, and epidemiologists who manage or research soft tissue and bone tumours. (who.int)
  • Soon after birth, the nipples are raised from the shallow mammary pits by proliferation of the surrounding connective tissue. (medscape.com)
  • Our results support the hypothesis that SRCT of bone of soft tissue with the t(11;22) form a single biologic entity displaying varying degrees of neuroectodermal differentiation. (nih.gov)
  • Another opinion suggested a differentiation-metaplasia capacity of neuroectodermal tissue [ 20 ]. (hindawi.com)
  • The outcome after surgery is excellent as these neoplasms are generally benign in nature. (sages.org)
  • 1 Subsequently, Chadwick et al 2 reported SMT in human immunodeficiency virus (HIV)-infected children and asserted the association between HIV and these rare neoplasms. (allenpress.com)
  • Extraskeletal osteosarcoma (EOS) is a rare malignant soft tissue neoplasm. (researchsquare.com)
  • Sections are included on all recognized neoplasms of the soft tissue and bone, as well as on genetic tumour syndromes affecting these sites. (who.int)
  • Malignancies of the soft tissues (6%) and bone (5%) account for more than 10% of cancers diagnosed in children, adolescents, and young adults. (drrathresearch.org)
  • Regressive changes of the tissues located at the surgical margins, such as cellular hyperbasophilia, nuclear chromatin condensations or tissue coarctation were not detected. (springer.com)
  • Gardner syndrome or familial adenomatous polyposis (FAP) is characterized by colorectal adenomatous polyps and soft and hard tissue neoplasms. (medscape.com)
  • Accessory or ectopic breast tissue responds to hormonal stimulation and may cause discomfort during menstrual cycles. (medscape.com)
  • This paper presents a 3-year-old girl who presented with a soft to firm, ill-defined swelling on the right breast with painful ulceration of the overlying skin. (usp.br)
  • Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc. (nih.gov)