Rare neoplasms of mesenchymal origin, usually benign, and most commonly involving the PLEURA (see SOLITARY FIBROUS TUMOR, PLEURAL). They also are found in extrapleural sites.
A rare neoplasm, usually benign, derived from mesenchymal fibroblasts located in the submesothelial lining of the PLEURA. It spite of its various synonyms, it has no features of mesothelial cells and is not related to malignant MESOTHELIOMA or asbestos exposure.
Neoplasms composed of fibrous tissue, the ordinary connective tissue of the body, made up largely of yellow or white fibers. The concept does not refer to neoplasms located in fibrous tissue.
A tumor composed of spindle cells with a rich vascular network, which apparently arises from pericytes, cells of smooth muscle origin that lie around small vessels. Benign and malignant hemangiopericytomas exist, and the rarity of these lesions has led to considerable confusion in distinguishing between benign and malignant variants. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1364)
A benign tumor of fibrous or fully developed connective tissue.
Neoplasms of the thin serous membrane that envelopes the lungs and lines the thoracic cavity. Pleural neoplasms are exceedingly rare and are usually not diagnosed until they are advanced because in the early stages they produce no symptoms.
A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.
Retroperitoneal neoplasms are a diverse group of tumors that originate in the retroperitoneal space, which is the area behind the peritoneum and includes the kidneys, adrenal glands, pancreas, and major blood vessels.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
The thin serous membrane enveloping the lungs (LUNG) and lining the THORACIC CAVITY. Pleura consist of two layers, the inner visceral pleura lying next to the pulmonary parenchyma and the outer parietal pleura. Between the two layers is the PLEURAL CAVITY which contains a thin film of liquid.
Surgical incision into the chest wall.
A large group of diseases which are characterized by a low prevalence in the population. They frequently are associated with problems in diagnosis and treatment.
Surgical operations on the nose and nasal cavity.
Glycoproteins found on immature hematopoietic cells and endothelial cells. They are the only molecules to date whose expression within the blood system is restricted to a small number of progenitor cells in the bone marrow.
Tumors or cancer of the PAROTID GLAND.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Facial neoplasms are abnormal growths or tumors that develop in the facial region, which can be benign or malignant, originating from various cell types including epithelial, glandular, connective tissue, and neural crest cells.
A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Neoplasms of the base of the skull specifically, differentiated from neoplasms of unspecified sites or bones of the skull (SKULL NEOPLASMS).
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
The part of the face that is below the eye and to the side of the nose and mouth.
Tumors or cancer of the pelvic region.
Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
Neoplasms of the bony orbit and contents except the eyeball.
An intermediate filament protein found in most differentiating cells, in cells grown in tissue culture, and in certain fully differentiated cells. Its insolubility suggests that it serves a structural function in the cytoplasm. MW 52,000.
A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
Endoscopic surgery of the pleural cavity performed with visualization via video transmission.
GRAY MATTER located in the dorsomedial part of the MEDULLA OBLONGATA associated with the solitary tract. The solitary nucleus receives inputs from most organ systems including the terminations of the facial, glossopharyngeal, and vagus nerves. It is a major coordinator of AUTONOMIC NERVOUS SYSTEM regulation of cardiovascular, respiratory, gustatory, gastrointestinal, and chemoreceptive aspects of HOMEOSTASIS. The solitary nucleus is also notable for the large number of NEUROTRANSMITTERS which are found therein.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

Defective expression of prohormone convertase 4 and enhanced expression of insulin-like growth factor II by pleural solitary fibrous tumor causing hypoglycemia. (1/30)

A 75-year-old man was admitted to our hospital because of unconsciousness. His plasma glucose was very low, but his serum levels of insulin and IGF-I were also low. He was found to have a giant solitary pleural tumor, which was completely resected, after which his hypoglycemia ameliorated postoperatively. Histologically, the tumor was consistent with the pathological diagnosis of a solitary fibrous tumor derived from the pleura. Immunohistochemical study revealed positive immunostaining for IGF-II in tumor cells. The presence of high molecular weight (HMW) form of IGF-II in the tumor tissue and patient's serum was confirmed by Western blot analysis. Steady-state mRNA levels of IGF-II and prohormone convertases (PC) 4, a potential protease responsible for IGF-II processing, as determined by RT-PCR were about 14-fold greater and 5-fold less in the tumor tissue than those in normal placental tissue, respectively. Therefore, it is suggested that biologically active, unprocessed HMW form of IGF-II generated from the impaired processing of IGF-II precursor by the defective PC4 expression in the tumor was responsible for the non-islet cell tumor hypoglycemia (NICTH) in the present case.  (+info)

Solitary fibrous pleural tumor. (2/30)

Solitary fibrous pleural tumors are rare masses of mesenchymal origin that may be mistaken for mesothelioma. A positive staining of vimentin, negative staining of cytoplasmic keratin, and expression of the CD34 antigen can confirm the presence of a solitary fibrous pleural tumor. Although most tumors of this type are benign, they possess a malignant potential and thus should be excised. We report a case of a 63-year-old man who had an inconclusive biopsy of a lung lesion 15 years ago. Further testing after excision revealed a solitary fibrous pleural tumor. A brief discussion of the clinical presentation and incidence of these tumors is included.  (+info)

Solitary fibrous tumor of the pleura presenting with syncope episodes when coughing. (3/30)

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A case of recurrence and rapid growth of pleural solitary fibrous tumor 8 years after initial surgery. (4/30)

A 69-year-old woman underwent resection of a solitary fibrous tumor (SFT) of the left pleura in April 1997 and of locally recurrent SFT in the left thoracic cavity in September 2003. A postoperative follow-up chest CT scan in March 2005 revealed pleural thickening at two sites of the left thoracic cavity. A further chest CT scan performed in September of the same year showed the enlarging tendency of the lesions, suggesting SFT recurrence, for which surgery was performed in January 2006. The two resected tumors were benign SFT, and were diagnosed as locally recurrent SFT in the left thoracic cavity. It has been reported that despite its benign histopathology, pleural SFT recurs more than once after surgery, and the interval between recurrences tends to shorten from the second recurrence. In this patient, the tumor recurred twice and showed a rapidly enlarging tendency at the time of the second recurrence, suggesting the need for careful follow-up at short intervals.  (+info)

Surgically cured hypoglycemia secondary to pleural solitary fibrous tumour: case report and update review on the Doege-Potter syndrome. (5/30)

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Solitary fibrous tumor of the pleura presenting dry cough induced by postural position. (6/30)

Solitary fibrous tumor of the pleura is one of the uncommon diseases. About 40% of solitary fibrous tumors of the pleura are of a visceral and peduncled type. Several visceral pleural tumors have motility. A proof of motility of the intrathoracic tumor is useful for preoperative diagnosis. We report a resected case of solitary fibrous tumor of the pleura presenting dry cough induced by postural position.  (+info)

Localized pleural mesothelioma causing cranial vena cava syndrome in a dog. (7/30)

A 9-year-old female crossbred dog was presented to the Hospital Universitario Veterinario Rof Codina (Universidad de Santiago de Compostela, Lugo, Spain) for acute onset of severe, progressive swelling of the head, neck, and cranial trunk. Survey radiographs and ultrasonography revealed a large, heterogeneous mass in the cranial mediastinum, compressing or growing into a large blood vessel within the cranial mediastinum and displacing the heart dorsocaudally. At postmortem examination, the mass was diagnosed as a large, localized mesothelioma. Localized mesotheliomas are rare neoplasms in dogs but should be considered as a possible differential diagnosis for cranial vena cava syndrome. The anatomic distribution and clinical features of mesothelioma in the present report are similar to other cases in humans.  (+info)

Localized malignant pleural mesothelioma showing a thoracic mass and metastasizing to the stomach. (8/30)

Malignant mesothelioma typically shows either diffuse tumors or multiple pleura-based nodules. Localized malignant mesothelioma is rare. In this case report, a 70-year-old man with left chest wall tumor underwent tumor resection, and the lesion was pathologically diagnosed as biphasic malignant mesothelioma. Tumor recurrence was detected in the stomach due to vomiting of blood, and also spread to the mediastinal lymph node, and bone 3 months postoperatively. Total gastrectomy was performed and the histopathological diagnosis of metastasis of mesothelioma was made. In the previously reported cases, all of the localized malignant mesothelioma arose in the pleural space and there was no metastasis of localized malignant mesothelioma to the stomach. In the present case, gross and histological examinations were performed for both the primary lesion and gastric metastatic tumor. Though it was very difficult to distinguish mesothelioma from sarcoma and other chest wall tumors, immunochemical staining was able to facilitate making the diagnosis. This case suggests that localized malignant mesothelioma is capable of showing multiple forms and a variety of clinical courses. Localized malignant mesothelioma can arise primarily from the chest wall.  (+info)

Solitary fibrous tumors (SFTs) are rare type of slow-growing neoplasms that typically arise from the pleura, the thin layer of tissue that covers the lungs. However, they can also occur in other locations throughout the body such as the peritoneum, meninges, and deep soft tissues.

SFTs are composed of spindle-shaped cells arranged in a patternless architecture, with a variably collagenous stroma. They are usually well-circumscribed and encapsulated, although they can become invasive in some cases. The cellularity of SFTs varies from low to high, and the tumors can contain staghorn vessels, which are dilated blood vessels with a branching pattern.

The majority of SFTs are benign, but approximately 10-20% of them can be malignant or have aggressive behavior, with potential for local recurrence and distant metastasis. The diagnosis of SFT is usually made by histopathological examination of the tumor tissue, which shows characteristic features such as CD34 and Bcl-2 positivity on immunohistochemistry.

Treatment options for SFTs include surgical resection with wide margins, radiation therapy, and systemic therapy with chemotherapy or targeted agents. The choice of treatment depends on the location, size, and behavior of the tumor, as well as the patient's overall health status. Regular follow-up is necessary to monitor for recurrence or metastasis.

A Solitary Fibrous Tumor (SFT) is a rare type of soft tissue neoplasm that can occur in various locations throughout the body. When it develops in the pleura, which is the thin layer of tissue that surrounds the lungs, it is referred to as a "Solitary Fibrous Tumor, Pleural."

These tumors are typically slow-growing and can range in size from a few centimeters to over 20 cm in diameter. They are usually asymptomatic and are often discovered incidentally on chest X-rays or CT scans performed for other reasons. However, larger tumors may cause symptoms such as cough, chest pain, or shortness of breath.

SFTs, Pleural are typically well-circumscribed, encapsulated masses that can be removed surgically with curative intent. The histological features of SFTs include a patternless architecture with alternating hypocellular and hypercellular areas, along with a prominent network of thin-walled blood vessels.

Immunohistochemical staining is often used to confirm the diagnosis of SFT, with positivity for CD34 and STAT6 being characteristic features. The prognosis for patients with SFTs, Pleural is generally good, with a low risk of recurrence following surgical resection. However, some cases may exhibit more aggressive behavior, and long-term follow-up is recommended.

Neoplasms of fibrous tissue are abnormal growths or tumors that originate from fibroblasts, the cells responsible for producing connective tissue in the body. These neoplasms can be benign or malignant (cancerous). Benign fibrous neoplasms include fibromas and fibrohistiocytic tumors, while malignant fibrous neoplasms are called fibrosarcomas. Fibrosarcomas are aggressive tumors that invade surrounding tissues and can metastasize (spread) to other parts of the body.

Fibrous tissue neoplasms can occur in any part of the body, but they are most commonly found in the soft tissues such as muscles, tendons, and ligaments. They can also develop in bones, where they are called osteosarcomas. Symptoms of fibrous tissue neoplasms depend on their size and location, but may include a painless mass or swelling, limited mobility, or pain if the tumor is pressing on nerves or blood vessels.

Diagnosis of fibrous tissue neoplasms typically involves imaging tests such as X-rays, CT scans, or MRI scans, followed by a biopsy to confirm the type and grade of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up care is important to monitor for recurrence or metastasis.

Hemangiopericytoma is a rare type of soft tissue sarcoma, which is a cancer that develops from the cells that surround blood vessels. It specifically arises from the pericytes, which are cells that help regulate blood flow in capillaries. Hemangiopericytomas typically form in the membranes surrounding the brain and spinal cord (meninges), but they can also occur in other parts of the body such as the lungs, abdomen, or extremities.

These tumors usually grow slowly, but they can become aggressive and spread to other parts of the body (metastasize). Symptoms depend on the location of the tumor, but may include headaches, seizures, weakness, or numbness in the arms or legs. Diagnosis typically involves imaging tests like MRI or CT scans, followed by a biopsy to confirm the presence of cancer cells. Treatment usually consists of surgical removal of the tumor, often accompanied by radiation therapy and/or chemotherapy to help prevent recurrence or spread of the disease.

A fibroma is a benign (non-cancerous) tumor that consists primarily of fibrous or connective tissue. It can occur in various parts of the body, including the skin, mouth, and internal organs. The term "fibroma" is often used to describe any benign fibrous growth, but there are specific types of fibromas such as dermatofibroma (found in the skin), oral fibroma (found in the mouth), and benign fibrous histiocytoma (found in soft tissues).

It's important to note that while fibromas are generally harmless, they can cause discomfort or problems depending on their size and location. If a fibroma is causing issues or there's concern about its growth or malignancy, it should be evaluated by a healthcare professional for potential removal or further assessment.

Pleural neoplasms refer to abnormal growths or tumors that develop in the pleura, which is the thin, double layered membrane that surrounds the lungs and lines the inside of the chest wall. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Malignant pleural neoplasms are often associated with lung cancer, mesothelioma, or metastasis from other types of cancer. They can cause symptoms such as chest pain, cough, shortness of breath, and weight loss. Diagnosis typically involves imaging tests like X-rays or CT scans, followed by biopsy to confirm the type of tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

A lipoma is a common, benign (non-cancerous) soft tissue growth. It is composed of adipose or fatty tissue and typically found just beneath the skin, but they can also occur deeper within the body. Lipomas are usually round, moveable, and painless, although they may cause discomfort if they grow large enough to put pressure on nearby nerves or if they're located in a sensitive area. They generally grow slowly over time. Surgical removal is an option if the lipoma becomes bothersome or grows significantly in size. It's important to note that while lipomas are typically harmless, any new lumps or bumps should be evaluated by a healthcare professional to confirm the diagnosis and rule out other more serious conditions.

Retroperitoneal neoplasms refer to abnormal growths or tumors that develop in the retroperitoneal space. This is the area located behind the peritoneum, which is the membrane that lines the abdominal cavity and covers the abdominal organs. The retroperitoneal space contains several vital structures such as the kidneys, adrenal glands, pancreas, aorta, and lymphatic vessels.

Retroperitoneal neoplasms can be benign or malignant (cancerous). Malignant retroperitoneal neoplasms are often aggressive and can invade surrounding tissues and organs, leading to various complications. Common types of retroperitoneal neoplasms include lymphomas, sarcomas, and metastatic tumors from other primary sites. Symptoms may vary depending on the size and location of the tumor but can include abdominal or back pain, weight loss, and swelling in the legs. Diagnosis typically involves imaging studies such as CT scans or MRI, followed by a biopsy to determine the type and grade of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.

The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.

CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.

In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.

CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.

In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.

Soft tissue neoplasms refer to abnormal growths or tumors that develop in the soft tissues of the body. Soft tissues include muscles, tendons, ligaments, fascia, nerves, blood vessels, fat, and synovial membranes (the thin layer of cells that line joints and tendons). Neoplasms can be benign (non-cancerous) or malignant (cancerous), and their behavior and potential for spread depend on the specific type of neoplasm.

Benign soft tissue neoplasms are typically slow-growing, well-circumscribed, and rarely spread to other parts of the body. They can often be removed surgically with a low risk of recurrence. Examples of benign soft tissue neoplasms include lipomas (fat tumors), schwannomas (nerve sheath tumors), and hemangiomas (blood vessel tumors).

Malignant soft tissue neoplasms, on the other hand, can grow rapidly, invade surrounding tissues, and may metastasize (spread) to distant parts of the body. They are often more difficult to treat than benign neoplasms and require a multidisciplinary approach, including surgery, radiation therapy, and chemotherapy. Examples of malignant soft tissue neoplasms include sarcomas, such as rhabdomyosarcoma (arising from skeletal muscle), leiomyosarcoma (arising from smooth muscle), and angiosarcoma (arising from blood vessels).

It is important to note that soft tissue neoplasms can occur in any part of the body, and their diagnosis and treatment require a thorough evaluation by a healthcare professional with expertise in this area.

The pleura is the medical term for the double-layered serous membrane that surrounds the lungs and lines the inside of the chest cavity. The two layers of the pleura are called the parietal pleura, which lines the chest cavity, and the visceral pleura, which covers the surface of the lungs.

The space between these two layers is called the pleural cavity, which contains a small amount of lubricating fluid that allows the lungs to move smoothly within the chest during breathing. The main function of the pleura is to protect the lungs and facilitate their movement during respiration.

Thoracotomy is a surgical procedure that involves making an incision on the chest wall to gain access to the thoracic cavity, which contains the lungs, heart, esophagus, trachea, and other vital organs. The incision can be made on the side (lateral thoracotomy), back (posterolateral thoracotomy), or front (median sternotomy) of the chest wall, depending on the specific surgical indication.

Thoracotomy is performed for various indications, including lung biopsy, lung resection, esophagectomy, heart surgery, and mediastinal mass removal. The procedure allows the surgeon to directly visualize and access the organs within the thoracic cavity, perform necessary procedures, and control bleeding if needed.

After the procedure, the incision is typically closed with sutures or staples, and a chest tube may be placed to drain any accumulated fluid or air from the pleural space around the lungs. The patient will require postoperative care and monitoring in a hospital setting until their condition stabilizes.

A rare disease, also known as an orphan disease, is a health condition that affects fewer than 200,000 people in the United States or fewer than 1 in 2,000 people in Europe. There are over 7,000 rare diseases identified, and many of them are severe, chronic, and often life-threatening. The causes of rare diseases can be genetic, infectious, environmental, or degenerative. Due to their rarity, research on rare diseases is often underfunded, and treatments may not be available or well-studied. Additionally, the diagnosis of rare diseases can be challenging due to a lack of awareness and understanding among healthcare professionals.

Nasal surgical procedures, also known as nasal surgery or rhinoplasty, refer to various surgical operations performed on the nose. These procedures can be either functional (to improve breathing) or cosmetic (to change the appearance of the nose). Some common nasal surgical procedures include:

1. Septoplasty: a surgical procedure to correct a deviated septum, which is the partition between the two nostrils. This procedure helps to improve airflow through the nose and alleviate breathing difficulties.
2. Turbinate reduction: a procedure that reduces the size of the turbinates (structures inside the nasal passages that help warm, humidify, and filter the air we breathe) to improve nasal breathing.
3. Rhinoplasty: a cosmetic procedure that reshapes or resizes the nose to achieve a more desirable appearance. This can involve changing the shape of the cartilage, bone, or soft tissue in the nose.
4. Nasal polyp removal: a procedure to remove nasal polyps, which are non-cancerous growths that can obstruct the nasal passages and cause breathing difficulties.
5. Sinus surgery: a procedure to open up blocked sinuses and improve drainage. This can be done through various techniques, including endoscopic sinus surgery, balloon sinuplasty, or traditional sinus surgery.
6. Nose reconstruction: a procedure to repair or reconstruct the nose after trauma, cancer, or other medical conditions that have caused damage to the nose.

These are just a few examples of nasal surgical procedures. The specific type of procedure will depend on the individual patient's needs and goals.

CD34 is a type of antigen that is found on the surface of certain cells in the human body. Specifically, CD34 antigens are present on hematopoietic stem cells, which are immature cells that can develop into different types of blood cells. These stem cells are found in the bone marrow and are responsible for producing red blood cells, white blood cells, and platelets.

CD34 antigens are a type of cell surface marker that is used in medical research and clinical settings to identify and isolate hematopoietic stem cells. They are also used in the development of stem cell therapies and transplantation procedures. CD34 antigens can be detected using various laboratory techniques, such as flow cytometry or immunohistochemistry.

It's important to note that while CD34 is a useful marker for identifying hematopoietic stem cells, it is not exclusive to these cells and can also be found on other cell types, such as endothelial cells that line blood vessels. Therefore, additional markers are often used in combination with CD34 to more specifically identify and isolate hematopoietic stem cells.

Parotid neoplasms refer to abnormal growths or tumors in the parotid gland, which is the largest of the salivary glands and is located in front of the ear and extends down the neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign parotid neoplasms are typically slow-growing, painless masses that may cause facial asymmetry or difficulty in chewing or swallowing if they become large enough to compress surrounding structures. The most common type of benign parotid tumor is a pleomorphic adenoma.

Malignant parotid neoplasms, on the other hand, are more aggressive and can invade nearby tissues and spread to other parts of the body. They may present as rapidly growing masses that are firm or fixed to surrounding structures. Common types of malignant parotid tumors include mucoepidermoid carcinoma, adenoid cystic carcinoma, and squamous cell carcinoma.

The diagnosis of parotid neoplasms typically involves a thorough clinical evaluation, imaging studies such as CT or MRI scans, and fine-needle aspiration biopsy (FNAB) to determine the nature of the tumor. Treatment options depend on the type, size, and location of the neoplasm but may include surgical excision, radiation therapy, and chemotherapy.

Tumor markers are substances that can be found in the body and their presence can indicate the presence of certain types of cancer or other conditions. Biological tumor markers refer to those substances that are produced by cancer cells or by other cells in response to cancer or certain benign (non-cancerous) conditions. These markers can be found in various bodily fluids such as blood, urine, or tissue samples.

Examples of biological tumor markers include:

1. Proteins: Some tumor markers are proteins that are produced by cancer cells or by other cells in response to the presence of cancer. For example, prostate-specific antigen (PSA) is a protein produced by normal prostate cells and in higher amounts by prostate cancer cells.
2. Genetic material: Tumor markers can also include genetic material such as DNA, RNA, or microRNA that are shed by cancer cells into bodily fluids. For example, circulating tumor DNA (ctDNA) is genetic material from cancer cells that can be found in the bloodstream.
3. Metabolites: Tumor markers can also include metabolic products produced by cancer cells or by other cells in response to cancer. For example, lactate dehydrogenase (LDH) is an enzyme that is released into the bloodstream when cancer cells break down glucose for energy.

It's important to note that tumor markers are not specific to cancer and can be elevated in non-cancerous conditions as well. Therefore, they should not be used alone to diagnose cancer but rather as a tool in conjunction with other diagnostic tests and clinical evaluations.

Facial neoplasms refer to abnormal growths or tumors that develop in the tissues of the face. These growths can be benign (non-cancerous) or malignant (cancerous). Facial neoplasms can occur in any of the facial structures, including the skin, muscles, bones, nerves, and glands.

Benign facial neoplasms are typically slow-growing and do not spread to other parts of the body. Examples include papillomas, hemangiomas, and neurofibromas. While these tumors are usually harmless, they can cause cosmetic concerns or interfere with normal facial function.

Malignant facial neoplasms, on the other hand, can be aggressive and invasive. They can spread to other parts of the face, as well as to distant sites in the body. Common types of malignant facial neoplasms include basal cell carcinoma, squamous cell carcinoma, and melanoma.

Treatment for facial neoplasms depends on several factors, including the type, size, location, and stage of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. It is important to seek medical attention promptly if you notice any unusual growths or changes in the skin or tissues of your face.

Mesenchymoma is a very rare type of tumor that contains a mixture of different types of mesenchymal tissues, such as muscle, fat, bone, cartilage, or fibrous tissue. It typically occurs in children and young adults, and can be found in various parts of the body, including the head, neck, retroperitoneum (the area behind the abdominal cavity), and the limbs.

Mesenchymomas are usually slow-growing and may not cause any symptoms until they reach a large size. Treatment typically involves surgical removal of the tumor, but radiation therapy or chemotherapy may also be used in some cases. The prognosis for mesenchymoma depends on several factors, including the location and size of the tumor, the patient's age and overall health, and the specific types of tissue that are present in the tumor.

Skull base neoplasms refer to abnormal growths or tumors located in the skull base, which is the region where the skull meets the spine and where the brain connects with the blood vessels and nerves that supply the head and neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can arise from various types of cells in this area, including bone, nerve, glandular, and vascular tissue.

Skull base neoplasms can cause a range of symptoms depending on their size, location, and growth rate. Some common symptoms include headaches, vision changes, hearing loss, facial numbness or weakness, difficulty swallowing, and balance problems. Treatment options for skull base neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. The specific treatment plan will depend on the type, size, location, and stage of the tumor, as well as the patient's overall health and medical history.

Immunohistochemistry (IHC) is a technique used in pathology and laboratory medicine to identify specific proteins or antigens in tissue sections. It combines the principles of immunology and histology to detect the presence and location of these target molecules within cells and tissues. This technique utilizes antibodies that are specific to the protein or antigen of interest, which are then tagged with a detection system such as a chromogen or fluorophore. The stained tissue sections can be examined under a microscope, allowing for the visualization and analysis of the distribution and expression patterns of the target molecule in the context of the tissue architecture. Immunohistochemistry is widely used in diagnostic pathology to help identify various diseases, including cancer, infectious diseases, and immune-mediated disorders.

A "cheek" is the fleshy, muscular area of the face that forms the side of the face below the eye and above the jaw. It contains the buccinator muscle, which helps with chewing by moving food to the back teeth for grinding and also assists in speaking and forming facial expressions. The cheek also contains several sensory receptors that allow us to perceive touch, temperature, and pain in this area of the face. Additionally, there is a mucous membrane lining inside the mouth cavity called the buccal mucosa which covers the inner surface of the cheek.

Pelvic neoplasms refer to abnormal growths or tumors located in the pelvic region. These growths can be benign (non-cancerous) or malignant (cancerous). They can originate from various tissues within the pelvis, including the reproductive organs (such as ovaries, uterus, cervix, vagina, and vulva in women; and prostate, testicles, and penis in men), the urinary system (kidneys, ureters, bladder, and urethra), the gastrointestinal tract (colon, rectum, and anus), as well as the muscles, nerves, blood vessels, and other connective tissues.

Malignant pelvic neoplasms can invade surrounding tissues and spread to distant parts of the body (metastasize). The symptoms of pelvic neoplasms may vary depending on their location, size, and type but often include abdominal or pelvic pain, bloating, changes in bowel or bladder habits, unusual vaginal bleeding or discharge, and unintentional weight loss. Early detection and prompt treatment are crucial for improving the prognosis of malignant pelvic neoplasms.

Meningeal neoplasms, also known as malignant meningitis or leptomeningeal carcinomatosis, refer to cancerous tumors that originate in the meninges, which are the membranes covering the brain and spinal cord. These tumors can arise primarily from the meningeal cells themselves, although they more commonly result from the spread (metastasis) of cancer cells from other parts of the body, such as breast, lung, or melanoma.

Meningeal neoplasms can cause a variety of symptoms, including headaches, nausea and vomiting, mental status changes, seizures, and focal neurological deficits. Diagnosis typically involves imaging studies (such as MRI) and analysis of cerebrospinal fluid obtained through a spinal tap. Treatment options may include radiation therapy, chemotherapy, or surgery, depending on the type and extent of the tumor. The prognosis for patients with meningeal neoplasms is generally poor, with a median survival time of several months to a year.

Orbital neoplasms refer to abnormal growths or tumors that develop in the orbit, which is the bony cavity that contains the eyeball, muscles, nerves, fat, and blood vessels. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can arise from various types of cells within the orbit.

Orbital neoplasms can cause a variety of symptoms depending on their size, location, and rate of growth. Common symptoms include protrusion or displacement of the eyeball, double vision, limited eye movement, pain, swelling, and numbness in the face. In some cases, orbital neoplasms may not cause any noticeable symptoms, especially if they are small and slow-growing.

There are many different types of orbital neoplasms, including:

1. Optic nerve glioma: a rare tumor that arises from the optic nerve's supportive tissue.
2. Orbital meningioma: a tumor that originates from the membranes covering the brain and extends into the orbit.
3. Lacrimal gland tumors: benign or malignant growths that develop in the lacrimal gland, which produces tears.
4. Orbital lymphangioma: a non-cancerous tumor that arises from the lymphatic vessels in the orbit.
5. Rhabdomyosarcoma: a malignant tumor that develops from the skeletal muscle cells in the orbit.
6. Metastatic tumors: cancerous growths that spread to the orbit from other parts of the body, such as the breast, lung, or prostate.

The diagnosis and treatment of orbital neoplasms depend on several factors, including the type, size, location, and extent of the tumor. Imaging tests, such as CT scans and MRI, are often used to visualize the tumor and determine its extent. A biopsy may also be performed to confirm the diagnosis and determine the tumor's type and grade. Treatment options include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Vimentin is a type III intermediate filament protein that is expressed in various cell types, including mesenchymal cells, endothelial cells, and hematopoietic cells. It plays a crucial role in maintaining cell structure and integrity by forming part of the cytoskeleton. Vimentin is also involved in various cellular processes such as cell division, motility, and intracellular transport.

In addition to its structural functions, vimentin has been identified as a marker for epithelial-mesenchymal transition (EMT), a process that occurs during embryonic development and cancer metastasis. During EMT, epithelial cells lose their polarity and cell-cell adhesion properties and acquire mesenchymal characteristics, including increased migratory capacity and invasiveness. Vimentin expression is upregulated during EMT, making it a potential target for therapeutic intervention in cancer.

In diagnostic pathology, vimentin immunostaining is used to identify mesenchymal cells and to distinguish them from epithelial cells. It can also be used to diagnose certain types of sarcomas and carcinomas that express vimentin.

Hypoglycemia is a medical condition characterized by an abnormally low level of glucose (sugar) in the blood. Generally, hypoglycemia is defined as a blood glucose level below 70 mg/dL (3.9 mmol/L), although symptoms may not occur until the blood sugar level falls below 55 mg/dL (3.0 mmol/L).

Hypoglycemia can occur in people with diabetes who are taking insulin or medications that increase insulin production, as well as those with certain medical conditions such as hormone deficiencies, severe liver illnesses, or disorders of the adrenal glands. Symptoms of hypoglycemia include sweating, shaking, confusion, rapid heartbeat, and in severe cases, loss of consciousness or seizures.

Hypoglycemia is typically treated by consuming fast-acting carbohydrates such as fruit juice, candy, or glucose tablets to rapidly raise blood sugar levels. If left untreated, hypoglycemia can lead to serious complications, including brain damage and even death.

Thoracic surgery, video-assisted (VATS) is a minimally invasive surgical technique used to diagnose and treat various conditions related to the chest cavity, including the lungs, pleura, mediastinum, esophagus, and diaphragm. In VATS, a thoracoscope, a type of endoscope with a camera and light source, is inserted through small incisions in the chest wall to provide visualization of the internal structures. The surgeon then uses specialized instruments to perform the necessary surgical procedures, such as biopsies, lung resections, or esophageal repairs. Compared to traditional open thoracic surgery, VATS typically results in less postoperative pain, shorter hospital stays, and quicker recoveries for patients.

The solitary nucleus, also known as the nucleus solitarius, is a collection of neurons located in the medulla oblongata region of the brainstem. It plays a crucial role in the processing and integration of sensory information, particularly taste and visceral afferent fibers from internal organs. The solitary nucleus receives inputs from various cranial nerves, including the glossopharyngeal (cranial nerve IX) and vagus nerves (cranial nerve X), and is involved in reflex responses related to swallowing, vomiting, and cardiovascular regulation.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Synovial sarcoma is a rare type of cancer that typically develops in the soft tissues surrounding the joints, such as the synovial membrane, which lines the joint capsules. Despite its name, synovial sarcoma does not necessarily arise from the synovium. It is called so due to its resemblance to this tissue under a microscope.

This form of sarcoma primarily affects young adults and can be found in various parts of the body, but it most commonly occurs in the extremities, particularly near the knees. Synovial sarcoma is characterized by specific genetic changes that result in the formation of fusion proteins, which contribute to uncontrolled cell growth and tumor development.

There are two main subtypes of synovial sarcoma: monophasic and biphasic. Monophasic synovial sarcoma is composed of either spindle-shaped (spaghetti-like) cells or epithelioid (roundish) cells, while biphasic synovial sarcoma contains both types of cells. A third subtype, called poorly differentiated synovial sarcoma, has a more aggressive behavior and is composed of small round cells that do not resemble the typical spindle or epithelioid cells.

Treatment for synovial sarcoma usually involves surgical removal of the tumor, often followed by radiation therapy and/or chemotherapy to reduce the risk of recurrence and metastasis. The prognosis varies depending on factors such as the size and location of the tumor, the patient's age, and the presence of metastases at diagnosis.

Mesothelioma is a rare and aggressive form of cancer that develops in the mesothelial cells, which are the thin layers of tissue that cover many of the internal organs. The most common site for mesothelioma to occur is in the pleura, the membrane that surrounds the lungs. This type is called pleural mesothelioma. Other types include peritoneal mesothelioma (which occurs in the lining of the abdominal cavity) and pericardial mesothelioma (which occurs in the lining around the heart).

Mesothelioma is almost always caused by exposure to asbestos, a group of naturally occurring minerals that were widely used in construction, insulation, and other industries because of their heat resistance and insulating properties. When asbestos fibers are inhaled or ingested, they can become lodged in the mesothelium, leading to inflammation, scarring, and eventually cancerous changes in the cells.

The symptoms of mesothelioma can take many years to develop after exposure to asbestos, and they may include chest pain, coughing, shortness of breath, fatigue, and weight loss. Treatment options for mesothelioma depend on the stage and location of the cancer, but may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Unfortunately, the prognosis for mesothelioma is often poor, with a median survival time of around 12-18 months after diagnosis.

Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.

... "giant solitary fibrous tumor", no such "giant" variant has yet been recognized within the most widely used pleural tumor ... Solitary fibrous tumor (SFT), also known as fibrous tumor of the pleura, is a rare mesenchymal tumor originating in the pleura ... evidenced by some deeply yellow necrotic areas Solitary fibrous tumor - low magnification. H&E stain. Solitary fibrous tumor - ... including localized fibrous tumor, benign mesothelioma, localized fibrous mesothelioma, submesothelial fibroma, and pleural ...
Actual rates of hypoglycemia associated with a fibrous tumor are quite rare (a 1981 study of 360 solitary fibrous tumors of the ... Light, Richard J. (2007). Pleural diseases. Hagerstwon, MD: Lippincott Williams & Wilkins. pp. 172-3. ISBN 978-0-7817-6957-0. ( ... Balduyck B, Lauwers P, Govaert K, Hendriks J, De Maeseneer M, Van Schil P (July 2006). "Solitary fibrous tumor of the pleura ... Briselli M, Mark EJ, Dickersin GR (June 1981). "Solitary fibrous tumors of the pleura: eight new cases and review of 360 cases ...
... pleural DSRCT) Pleural synovial sarcoma Pleural solitary fibrous tumor (pleural SFT, can be benign or less commonly malignant) ... Pleural tumors may be benign (i.e. solitary fibrous tumor) or malignant in nature. Pleural mesothelioma is a type of malignant ... Mesothelial tumors: pleural malignant mesothelioma. Pleural sarcomas Pleural angiosarcoma Pleural desmoplastic small round cell ... Pleurisy Pneumonia Pleural infections Pleural endometriosis Pleuritis Pleural mesothelial hyperplasia Pleural calcified fibrous ...
Balduyck B, Lauwers P, Govaert K, Hendriks J, De Maeseneer M, Van Schil P (Jul 2006). "Solitary fibrous tumor of the pleura ... syndrome in which hypoglycemia is associated with the presence of one or more non-islet fibrous tumors in the pleural cavity. ... IGF-2 is sometimes produced in excess in islet cell tumors and non-islet hypoglycemic cell tumors, causing hypoglycemia. Doege- ... Loss of imprinting of IGF-2 is a common feature in tumors seen in Beckwith-Wiedemann syndrome. As IGF-2 promotes development of ...
... sternomastoid tumor of infancy) Fibrous hamartoma of infancy Fibrous papule of the nose (benign solitary fibrous papule, ... primary lymphedema associated with yellow nails and pleural effusion) Category:Cutaneous conditions Dermatology List of ... solid glomus tumor, solitary glomus tumor) Granular cell tumor (Abrikossoff's tumor, Abrikossov's tumor, granular cell ... Schwann cell tumor) Solitary angiokeratoma Solitary cutaneous leiomyoma Solitary mastocytoma Solitary neurofibroma (plexiform ...
... non-islet cell tumor hypoglycemia,solitary fibrous tumor,thoracotomy,tumor-induced hypoglycemia ... Late-Onset Non-islet Cell Tumor Hypoglycemia Associated with a Pleural Solitary Fibrous Tumor ... Late-Onset Non-islet Cell Tumor Hypoglycemia Associated with a Pleural Solitary Fibrous Tumor. ... Keywords : Hypoglycemia, non-islet cell tumor hypoglycemia, solitary fibrous tumor, thoracotomy, tumor-induced hypoglycemia ...
They enter into the clinical and histological differential diagnoses of pleural malignant mesothelioma. ... A) Malignant solitary fibrous tumor. A 2 kilogram pleural solitary fibrous tumor in a 36-year-old female. The collagenous area ... A) Malignant solitary fibrous tumor. A 2 kilogram pleural solitary fibrous tumor in a 36-year-old female. The collagenous area ... How is malignant solitary fibrous tumors (SFTs) of the pleura staged?. What are the recurrence and metastasis rates for pleural ...
They enter into the clinical and histological differential diagnoses of pleural malignant mesothelioma. ... A) Malignant solitary fibrous tumor. A 2 kilogram pleural solitary fibrous tumor in a 36-year-old female. The collagenous area ... A) Malignant solitary fibrous tumor. A 2 kilogram pleural solitary fibrous tumor in a 36-year-old female. The collagenous area ... How is malignant solitary fibrous tumors (SFTs) of the pleura staged?. What are the recurrence and metastasis rates for pleural ...
... "giant solitary fibrous tumor", no such "giant" variant has yet been recognized within the most widely used pleural tumor ... Solitary fibrous tumor (SFT), also known as fibrous tumor of the pleura, is a rare mesenchymal tumor originating in the pleura ... evidenced by some deeply yellow necrotic areas Solitary fibrous tumor - low magnification. H&E stain. Solitary fibrous tumor - ... including localized fibrous tumor, benign mesothelioma, localized fibrous mesothelioma, submesothelial fibroma, and pleural ...
Pleural lesions: pleuritis, pleural plaque, pleural tumors (solitary fibrous tumors, malignant mesothelioma, metastatic tumors ... Testicular tumors. Classification and germ cell tumors.. Diseases and tumors of the prostate gland. Prostatitis, stromal and ... epithelial tumors, benign, borderline and malignant; stromal and sex cord tumors (germ cell tumors are discussed with the ... Diseases and tumors of the larynx: general features; specifically: nodules and polyps of the vocal cords; solitary papilloma ...
Very few fibroblastic/myofibroblastic tumors (eg, desmoid tumors, solitary fibrous tumor, and inflammatory myofibroblastic ... or pleural-based mesothelioma that extends into the mediastinum may mistakenly be considered as a primary mediastinal tumor/ ... The mediastinal solitary fibrous tumors more frequently show aggressive behavior compared with the nonmediastinal tumors. The ... MEDIASTINAL GERM CELL TUMORS. Germ cell tumors (GCTs) comprise 15% of adult mediastinal tumors as the second most common tumor ...
While the histologic classification of pleural malignant mesothelioma remains the same in the 2015 WHO classification as it was ... Classification of Tumors of the Pleura has recently been published. ... Another useful discovery was that the NAB2-STAT6 fusion is characteristic of solitary fibrous tumors. This led to development ... Solitary fibrous tumor; WWTR1-CAMTA1; p16; β-catenin. ... reliable immunohistochemical marker for solitary fibrous tumors ...
... is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. SFT used to be called localized ... is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. SFT used to be called localized ... Fluid escaping into the membranes around the lungs (pleural effusion) is a complication. ... Solitary fibrous tumor (SFT) is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. SFT ...
Surgical and radiation treatment of a paravertebral malignant solitary fibrous tumor: a case report and literature review. AME ... Malignant Peripheral Nerve Sheath Tumor. Malignant Pleural Effusion. Mediastinal Cancers. Mediastinal Tumors ...
We present two clinical cases of patients aged 36 and 74 with an orbital solitary fibrous tumour (SFT). The diagnosis was ... 1997) Bcl-2 expression in pleural and extrapleural solitary fibrous tumours. J Pathol 181: 362-367. ... Keywords: Solitary fibrous; Orbit tumor; Mesenchymal origin tumor; CD34. Download PDF Introduction. Solitary fibrous tumour ( ... 2011) Orbital solitary fibrous tumor: encompassing terminology for hemangiopericytoma, giant cell angiofibroma, and fibrous ...
Solitary Fibrous Tumor, Pleural Entry term(s). Benign Fibrous Mesothelioma Benign Fibrous Mesotheliomas Fibroma, Submesothelial ... Mesotheliomas, Solitary Fibrous Solitary Fibrous Mesothelioma Solitary Fibrous Mesotheliomas Solitary Fibrous Tumor of the ... Mesotheliomas, Solitary Fibrous. Solitary Fibrous Mesothelioma. Solitary Fibrous Mesotheliomas. Solitary Fibrous Tumor of the ... Fibrous Mesothelioma Fibrous Mesothelioma, Benign Fibrous Mesothelioma, Localized Fibrous Mesothelioma, Solitary Fibrous ...
pleural effusion. *small cell lung cancer. *solitary fibrous tumor. *thoracic cancer. *thymus cancer ... Pleural fluid microbiota as a biomarker for malignancy and prognosis Kwok, Benjamin; Wu, Benjamin G; Kocak, Ibrahim F; Sulaiman ...
They enter into the clinical and histological differential diagnoses of pleural malignant mesothelioma. ... Malignant Solitary Fibrous Tumor (A). A two kilogram pleural SFT in a 36 year old female. Collagenous area typical of that seen ... Malignant Solitary Fibrous Tumor (A). A two kilogram pleural SFT in a 36 year old female. Collagenous area typical of that seen ... Value of D2-40 in the differential diagnosis of pleural neoplasms with emphasis on its positivity in solitary fibrous tumor. ...
Solitary fibrous tumor associated with hypoglycemia: an example of the Doege-Potter syndrome. ... Solitary fibrous tumor associated with hypoglycemia: an example of the Doege-Potter syndrome. ...
Pleural solitary fibrous tumor. Big IGF-2. Surgical resection. [21]. 65, male. Retroperitoneal tumor. Retroperitoneal solitary ... Malignant solitary fibrous tumor. IGF-2. Surgical resection of turmor. [18]. 68, male. Liver. Solitary fibrous tumor. Big IGF-2 ... Solitary fibrous tumor. Elevated IGF-2/IGF-1 ratio. Surgical resection. [28]. 67, male. Pelvis. Solitary fibrous tumor. ... fibrous tumor. IGF-2, Big IGF-2. Surgical resection. [22]. 66, female. Right inferior thorax. Solitary fibrous tumor. IGF-2. ...
We found this to be suspicious for a solitary fibrous tumor. Based on this information, surgery was performed for tumor removal ... A 1-cm focal pleural thickening in the left posterior pleura was revealed on the chest computed tomography (CT) scan. ... Gastrointestinal: Solitary splenosis in the gastric fundus mimicking gastrointestinal stromal tumor. Okano, K; Inoue, K; Suzuki ... The peritoneum is a unique serosal membrane, which can be the site of primary tumors and, more commonly, secondary pathologic ...
Solitary Fibrous Tumor, Pleural; Kidney Neoplasms; Biliary Tract Neoplasms; Neoplasm Recurrence, Local; Lymphoma, T-Cell, ... PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation ... PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon ... Neuroendocrine Tumors; Gastrointestinal Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Lymphoma, Non- ...
Solitary Fibrous Tumour: Solitary fibrous tumours are rare growths of soft tissue cells that can form nearly anywhere in the ... Solitary fibrous tumours most often occur in the lining around the outside of the lungs (pleural solitary fibrous tumours). ... Solitary fibrous tumours have also been found in the head and neck, breast, kidney, prostate, spinal cord, and other sites. ... Gastrointestinal Stromal Tumour (GIST): These are soft-tissue sarcomas that can be located in any part of the digestive system ...
CONCLUSIONS:Solitary fibrous tumors may rarely present with hypoglycemia refractory to medical therapy. We present the first ... His medical history was relatively unremarkable with the exception of a large but asymptomatic solitary fibrous tumor ... from a solitary fibrous tumor. CASE REPORT:A 94-year-old man presented to the hospital following episodes of confusion, gait ... case of a nonagenarian patient with hypoglycemia secondary to ectopic production of IGF-2 from a solitary fibrous tumor managed ...
Value of D2-40 in the Differential Diagnosis of Pleural Neoplasms With Emphasis on Its Positivity in Solitary Fibrous Tumor ... Value of D2-40 in the Differential Diagnosis of Pleural Neoplasms With Emphasis on Its Positivity in Solitary Fibrous Tumor ... Clear Cell Meningioma: A Clinicopathologic Study of 18 Tumors and Examination of the Use of CD10, CA9, and RCC Antibodies to ... Clear Cell Meningioma: A Clinicopathologic Study of 18 Tumors and Examination of the Use of CD10, CA9, and RCC Antibodies ...
Case 35Pleural solitary fibrous tumor. Case 36Mediastinal lipomatosis. Case 37Pulmonary vein varix ...
... see SOLITARY FIBROUS TUMOR, PLEURAL). They also are found in extrapleural sites. HN - 2008 MH - Solitary Fibrous Tumor, Pleural ... HN - 2008; use MASTOCYTOMA 2003-2007 BX - Skin Mastocytoma MH - Solitary Fibrous Tumors UI - D054364 MN - C04.557.450.565. ... AN - note entry terms: MESOTHELIOMA is also available HN - 2008 BX - Fibrous Mesothelioma BX - Solitary Fibrous Mesothelioma MH ... It is characterized by solitary nodules or ulcerated tumors. AN - coordinate IM with SKIN NEOPLASMS (IM) HN - 2008 MH - ...
... see SOLITARY FIBROUS TUMOR, PLEURAL). They also are found in extrapleural sites. HN - 2008 MH - Solitary Fibrous Tumor, Pleural ... HN - 2008; use MASTOCYTOMA 2003-2007 BX - Skin Mastocytoma MH - Solitary Fibrous Tumors UI - D054364 MN - C04.557.450.565. ... AN - note entry terms: MESOTHELIOMA is also available HN - 2008 BX - Fibrous Mesothelioma BX - Solitary Fibrous Mesothelioma MH ... It is characterized by solitary nodules or ulcerated tumors. AN - coordinate IM with SKIN NEOPLASMS (IM) HN - 2008 MH - ...
... see SOLITARY FIBROUS TUMOR, PLEURAL). They also are found in extrapleural sites. HN - 2008 MH - Solitary Fibrous Tumor, Pleural ... HN - 2008; use MASTOCYTOMA 2003-2007 BX - Skin Mastocytoma MH - Solitary Fibrous Tumors UI - D054364 MN - C04.557.450.565. ... AN - note entry terms: MESOTHELIOMA is also available HN - 2008 BX - Fibrous Mesothelioma BX - Solitary Fibrous Mesothelioma MH ... It is characterized by solitary nodules or ulcerated tumors. AN - coordinate IM with SKIN NEOPLASMS (IM) HN - 2008 MH - ...
... see SOLITARY FIBROUS TUMOR, PLEURAL). They also are found in extrapleural sites. HN - 2008 MH - Solitary Fibrous Tumor, Pleural ... HN - 2008; use MASTOCYTOMA 2003-2007 BX - Skin Mastocytoma MH - Solitary Fibrous Tumors UI - D054364 MN - C04.557.450.565. ... AN - note entry terms: MESOTHELIOMA is also available HN - 2008 BX - Fibrous Mesothelioma BX - Solitary Fibrous Mesothelioma MH ... It is characterized by solitary nodules or ulcerated tumors. AN - coordinate IM with SKIN NEOPLASMS (IM) HN - 2008 MH - ...
... they have been described at many extra pleural sites, such as mediastinum. The treatment of choice is the extensive surgical ... resection that is curative for most benign lesions.We present the case of solitary fibrous tumor of the anterior mediastinum in ... Solitary fibrous tumors are uncommon soft tissue tumors initially reported only in the pleura but, in recent years, ... Solitary fibrous tumors are uncommon soft tissue tumors initially reported only in the pleura but, in recent years, they have ...
Ten years follow-up of pulmonary inflammatory pseudo-tumor ... Grossly, no parietal pleural involvement was noted, and no ... Well-circumscribed solitary nodules, with peripheral lower lobar predilection, constitute the usual radiologic manifestation of ... The WHO classification, on the other hand, divides IPT into compact spindle cell and hypocellular fibrous patterns[22]. ... It usually depends on the tumor size and the magnitude of surgical resection[27]. Tumors greater than 3 cm are usually not ...
... case of bilateral symmetric ectopic oral tonsillar tissue located at the ventral surface of the tongue along with two solitary ... In 1931, Klemperer and Rabin [1] described a series of localized solitary pleural tumors arising from the sub- pleural areolar ... Solitary Fibrous Tumor of the Oral Cavity: Clinicopathologic and Immunohistochemical Study of 21 Cases 10 ... Solitary Fibrous Tumor of the Oral Cavity: Clinicopathologic and Immunohistochemical Study of 21 Cases ...
Solitary Fibrous Tumor, Pleural. publications Timeline , Most Recent This graph shows the total number of publications written ... Pleural neoplasms are exceedingly rare and are usually not diagnosed until they are advanced because in the early stages they ... "Pleural Neoplasms" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Imaging in pleural mesothelioma: A review of the 15th International Conference of the International Mesothelioma Interest Group ...
  • Pleural Neoplasms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
  • Pleural neoplasms are exceedingly rare and are usually not diagnosed until they are advanced because in the early stages they produce no symptoms. (uchicago.edu)
  • This graph shows the total number of publications written about "Pleural Neoplasms" by people in this website by year, and whether "Pleural Neoplasms" was a major or minor topic of these publications. (uchicago.edu)
  • Below are the most recent publications written about "Pleural Neoplasms" by people in Profiles. (uchicago.edu)
  • While most tumors metastatic to the serous membranes are of epithelial origin, cytologists should be aware that non-epithelial neoplasms can also cause malignant effusions including sarcomas, melanomas, germ cell tumors, and, more rarely, brain tumors. (cytojournal.com)
  • Diagnosing non-epithelial malignancies in effusion specimens based entirely upon their cytomorphologic features is difficult because these neoplasms often exhibit considerable morphological overlap and their cytomorphology can differ from the original tumor. (cytojournal.com)
  • Common non-epithelial neoplasms that may cause malignant effusions include malignant melanoma, sarcomas, and other neoplasms including germ cell tumors [ Figure 1 ]. (cytojournal.com)
  • Secondary involvement of the mesentery from tumours elsewhere is much more common than primary mesenteric neoplasms such as desmoid tumour, inflammatory myofibroblastic tumour (IMFT), and others. (sajr.org.za)
  • Borges FK, Dornelles CMR, Vivian A. Solitary fibrous tumor of the pleura mimicking pleural effusion. (ufrgs.br)
  • Fluid escaping into the membranes around the lungs ( pleural effusion ) is a complication. (medlineplus.gov)
  • The most common findings on physical examination (79%) are signs of pleural effusion (eg, dullness to percussion, decreased breath sounds). (medscape.com)
  • A unilateral pleural effusion is seen in 30-80% of patients. (medscape.com)
  • The differential diagnosis of a malignant effusion is accordingly broad, especially for the small round blue cell tumors that includes not only mesenchymal tumors, but also non-mesenchymal tumors, such as neuroblastoma and Wilms tumor. (cytojournal.com)
  • Other rare non-epithelial malignancies that may be encountered in effusion cytology include neuroblastoma, Wilms tumor, and metastatic brain tumors. (cytojournal.com)
  • Solitary fibrous tumor (SFT), also known as fibrous tumor of the pleura, is a rare mesenchymal tumor originating in the pleura or at virtually any site in the soft tissue including seminal vesicle. (wikipedia.org)
  • About 80% of pleural SFTs originate in the visceral pleura, while 20% arise from parietal pleura. (wikipedia.org)
  • Robinson LA. Solitary fibrous tumor of the pleura. (wikipedia.org)
  • Briselli M, Mark EJ, Dickersin GR. Solitary fibrous tumors of the pleura: eight new cases and review of 360 cases in the literature" Cancer 1981;47:2678-89. (wikipedia.org)
  • A new World Health Organization (WHO) Classification of Tumors of the Pleura has recently been published. (nih.gov)
  • Finally, desmoid type fibromatosis, a locally aggressive tumor that can present in the pleura, has been shown to frequently have CTNNB1 gene mutations and express β-catenin by immunohistochemistry. (nih.gov)
  • Solitary fibrous tumor (SFT) is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. (medlineplus.gov)
  • Neoplasia poco frecuente, generalmente benigna, derivada de los fibroblastos mesenquimatosos localizados en la zona submesotelial de la PLEURA. (bvsalud.org)
  • Mesenchymal tumors most commonly derive from the pleura [3]. (amjcaserep.com)
  • Solitary fibrous tumors are uncommon soft tissue tumors initially reported only in the pleura but, in recent years, they have been described at many extra pleural sites, such as mediastinum. (omicsdi.org)
  • Decortication of the Lung Removal of fibrous deposits or restrictive membranes on the visceral or parietal pleura that interfere with ventilatory action. (nursekey.com)
  • 2. Maeda S, Sugita M, Sagawa M, Ueda Y, Sakuma T.: Solitary Fibrous Tumor of the Pleura Suddenly Induced Hypoglycemia before Surgical Treatment. (tohoku.ac.jp)
  • citation needed] Over the years pleural SFTs acquired a number of synonyms, including localized fibrous tumor, benign mesothelioma, localized fibrous mesothelioma, submesothelial fibroma, and pleural fibroma. (wikipedia.org)
  • SFT used to be called localized fibrous mesothelioma. (medlineplus.gov)
  • Moreover, the fibrous nature of the tumor has given rise to various other names, such as pleural fibroma, submesothelial fibroma, and localized fibrous tumor. (medscape.com)
  • While some researchers have proposed that a SFT occupying at least 40% of the affected hemithorax be considered a "giant solitary fibrous tumor", no such "giant" variant has yet been recognized within the most widely used pleural tumor classification scheme. (wikipedia.org)
  • Whereas pleural mesothelioma is highly associated with asbestos exposure , nonmesotheliomatous cancers have generally not been proven to result from exposure to airborne asbestos. (medscape.com)
  • [ 11 ] SFTs were initially incorrectly considered to be a localized form of fibrous mesothelioma. (medscape.com)
  • The use of names that include mesothelioma for this tumor is discouraged because of potential confusion with diffuse malignant mesothelioma, a much more serious disease. (wikipedia.org)
  • While the histologic classification of pleural malignant mesothelioma remains the same in the 2015 WHO classification as it was in the 2004 classification, multiple new observations have been recorded. (nih.gov)
  • Considerations for Imaging of Malignant Pleural Mesothelioma: A Consensus Statement from the International Mesothelioma Interest Group. (uchicago.edu)
  • Imaging in pleural mesothelioma: A review of the 15th International Conference of the International Mesothelioma Interest Group. (uchicago.edu)
  • Comparison of Nuclear Grade, Necrosis, and Histologic Subtype Between Biopsy and Resection in Pleural Malignant Mesothelioma: An International Multi-Institutional Analysis. (uchicago.edu)
  • Gemcitabine with or without ramucirumab as second-line treatment for malignant pleural mesothelioma (RAMES): a randomised, double-blind, placebo-controlled, phase 2 trial. (uchicago.edu)
  • Randomized Study of Maintenance Pemetrexed Versus Observation for Treatment of Malignant Pleural Mesothelioma: CALGB 30901. (uchicago.edu)
  • Treatment patterns among patients with malignant pleural mesothelioma: An Italian, population-based nationwide study. (uchicago.edu)
  • Optimization of response classification criteria for patients with malignant pleural mesothelioma, a validation study. (uchicago.edu)
  • EURACAN/IASLC Proposals for Updating the Histologic Classification of Pleural Mesothelioma: Towards a More Multidisciplinary Approach. (uchicago.edu)
  • Radiologic Considerations and Standardization of Malignant Pleural Mesothelioma Imaging Within Clinical Trials: Consensus Statement from the NCI Thoracic Malignancy Steering Committee - International Association for the Study of Lung Cancer - Mesothelioma Applied Research Foundation Clinical Trials Planning Meeting. (uchicago.edu)
  • More common diseases, such as benign asbestos-related pleural disease and metastatic adenocarcinoma, can look radiographically identical to mesothelioma. (medscape.com)
  • The most common mesothelioma finding on radiographs is unilateral, concentric, plaquelike, or nodular pleural thickening (as seen in the images below). (medscape.com)
  • Calcified pleural plaques are present in 20% of patients with mesothelioma and are usually related to the previous asbestos exposure. (medscape.com)
  • In addition to the above types, there is also benign mesothelioma in the lungs and chest cavity called solitary fibrous tumors. (alber.id)
  • Small malignant pleural effusions may not be observed on standard radiographs. (medscape.com)
  • Is it important to determine pleural fluid amylase in patients with malignant pleural effusions? (ers-education.org)
  • 8-13 Tyrosine kinase inhibitors (TKI) (imatinib, sunitinib, and regorafenib) have dramatically changed the treatment landscape and outcomes for gastrointestinal stromal tumour (GIST), one of the most common STS subtypes. (emjreviews.com)
  • Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. (allenpress.com)
  • Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
  • To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
  • Data were gathered from a PubMed search of peer-reviewed literature on mediastinal tumors. (allenpress.com)
  • 1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
  • Anterior mediastinal solitary fibrous tumor resection by da Vinci® Surgical System in obese patient. (omicsdi.org)
  • The tumor can rigidly encase the lung, causing compression of lung parenchyma, diaphragm elevation, intercostal space narrowing, and mediastinal shift toward the tumor. (medscape.com)
  • These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
  • Most tumors metastatic to the serous membranes are of epithelial origin. (cytojournal.com)
  • Atypical lipomatous tumors are generally considered to be low-grade sarcomas, with a strong propensity to recurrence but little metastatic potential. (medscape.com)
  • Primary Cutaneous Neuroendocrine Tumors Ceruminous gland tumors are discussed in Tumors of the Ear Canal. (merckvetmanual.com)
  • Solitary fibrous tumour (SFT) is an uncommon neoplasm at the orbital level that behaves in benign way in most cases [ 1 ]. (scitechnol.com)
  • Some SFTs are associated with the paraneoplastic Doege-Potter syndrome, which is caused by tumor production of IGF-2. (wikipedia.org)
  • Solitary fibrous tumor associated with hypoglycemia: an example of the Doege-Potter syndrome. (ox.ac.uk)
  • A rare cause of Whipple's triad is non-islet cell tumor hypoglycemia (NICTH) associated with a solitary fibrous tumor (SFT), commonly referred to as Doege-Potter syndrome [2]. (amjcaserep.com)
  • Solitary fibrous tumours are rare growths of soft tissue cells that can form nearly anywhere in the body. (suratoncologycentre.in)
  • Solitary fibrous tumours most often occur in the lining around the outside of the lungs (pleural solitary fibrous tumours). (suratoncologycentre.in)
  • In 1994, the WHO adopted the International Association for the Study of Lung Cancer (IASLC) pathology panel to comprise the core membership of the WHO committee, to develop a new revised classification of lung and pleural tumours. (ersjournals.com)
  • 2 The MRI appearance of desmoid tumours depends on the relative proportion of cellular, myxoid and fibrous components. (sajr.org.za)
  • 1 - 3 Intracranial brain tumors, most commonly medulloblastoma [ Figure 2 ], can metastasize to the peritoneal cavity via ventriculo-peritoneal shunts used to divert excess cerebrospinal fluid. (cytojournal.com)
  • Hemothorax Accumulation of blood, serosanguineous fluid, or both within the pleural cavity compromising lung expansion. (nursekey.com)
  • These tumors of dogs and, rarely, cats are most frequently identified on the head (including ears, lips, and oral cavity) and extremities of mature adult to senior animals. (merckvetmanual.com)
  • The World Health Organization (2020) classified SFT as a specific type of tumor in the category of malignant fibroblastic and myofibroblastic tumors. (wikipedia.org)
  • 3 Inflammatory myofibroblastic tumour appears as a hypo or iso-attenuating mass compared with skeletal muscle depending on the amount of myxoid or collagenous stroma, respectively. (sajr.org.za)
  • Hemangiopericytoma Myopericytoma Gross pathology of an atypical solitary fibrous tumor, evidenced by some deeply yellow necrotic areas Solitary fibrous tumor - low magnification. (wikipedia.org)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • Overlapping lung and pleural involvement in individual cases has given rise to the more inclusive term "pleuropulmonary" synovial sarcoma. (medscape.com)
  • High-resolution computed tomography scan of the thorax showed a 19.5 cm × 16.6 cm × 23.8 cm mass in the left hemithorax, and a microscopic examination of a biopsy specimen of which was consistent with the diagnosis of solitary fibrous tumor. (endocrinolrespract.org)
  • Post-operatively, histopatho- logical diagnosis of solitary fibrous tumor was confirmed. (endocrinolrespract.org)
  • Although they are often very large tumors (up to 40 cm. in diameter), over half are asymptomatic at diagnosis. (wikipedia.org)
  • The patient was referred to neurosurgery after confirming the diagnosis and because of intracranial invasion of the tumour. (scitechnol.com)
  • When hypoglycemia does occur in such individuals, an uncommon but important diagnosis to consider is non-islet cell tumor hypoglycemia (NICTH). (medscape.com)
  • As an ectopic tonsil may simulate a benign soft tissue tumor, this case series highlights the importance of this entity in our clinical differential diagnosis of oral soft tissue masses. (9lib.co)
  • Tumour classification systems provide the foundation for tumour diagnosis and patient therapy and a critical basis for epidemiological and clinical studies. (ersjournals.com)
  • 4 Differential diagnosis includes desmoid tumour and solitary fibrous tumour. (sajr.org.za)
  • Maldar AN, Chauhan PH, Lala M, Deshpande R. Late-onset non-islet cell tumor hypoglycemia associated with a pleural solitary fibrous tumor. (endocrinolrespract.org)
  • Review of recent reported cases of NICTH identified widespread anatomic locations and varied pathologic diagnoses of tumors associated with paraneoplastic production of IGF-2 causing hypoglycemia. (medscape.com)
  • Definitive management of hypoglycemia associated with paraneoplastic production of IGF-2 consists of resection of the tumor responsible for IGF-2 production. (medscape.com)
  • Solitary fibrous tumors may rarely present with hypoglycemia refractory to medical therapy. (amjcaserep.com)
  • We present the first reported case of a nonagenarian patient with hypoglycemia secondary to ectopic production of IGF-2 from a solitary fibrous tumor managed with surgical resection. (amjcaserep.com)
  • The etiology of hypoglycemia outside of the setting of diabetes mellitus is one with multiple life-threatening diagnoses including malnutrition, critical illness, and insulin-producing tumors classically associated with Whipple's triad. (amjcaserep.com)
  • Lipomas are common benign mesenchymal tumors. (medscape.com)
  • Genetic studies also led to the finding that WWTR1-CAMTA1 fusions are useful diagnostic markers for epithelioid hemangioendotheliomas, which can present as pleural-based masses. (nih.gov)
  • Diffuse pleural thickening or extensive lobular pleural-based masses are seen in about 50% of cases. (medscape.com)
  • Solitary fibrous tumors, should they always considered to be benign gigantic masses? (tgcd.org.tr)
  • They appear as solitary or multiple irregular hypoechoic masses with heterogeneous echotexture and increased echogenicity in the surrounding mesentery and omentum on USG and show increased internal vascularity on colour Doppler. (sajr.org.za)
  • These slow-growing, benign fatty tumors form soft, lobulated masses enclosed by a thin, fibrous capsule. (medscape.com)
  • Pleural effusions are common and may obscure the presence of the underlying pleural thickening. (medscape.com)
  • The treatment of choice for both benign and malignant SFT is complete en bloc surgical resection. (wikipedia.org)
  • It is diagnosed using immunohistochemical technique and the treatment of choice is surgical resection of the tumour in order to prevent recurrences. (scitechnol.com)
  • The treatment of choice is the extensive surgical resection that is curative for most benign lesions.We present the case of solitary fibrous tumor of the anterior mediastinum in obese patient (BMI: 34.3) undergoing complete surgical resection by robotic-assisted thoracoscopic surgery with da Vinci® Surgical System.Robotic-assisted thoracoscopic surgery with da Vinci® Surgical System is an interesting option for obese patient, at higher risk for deep sternal wound infection. (omicsdi.org)
  • 4. Maeda S, Takahashi S, Koike K, Sato M.: Preferred Surgical Approach for Dumbbell-Shaped Tumors in the Posterior Mediastinum. (tohoku.ac.jp)
  • Most of these tumors are locally confined, and complete but conservative surgical excision is the treatment of choice. (merckvetmanual.com)
  • When tumors are multiple or when surgical excision is not feasible, radiation therapy appears to be the best secondary treatment. (merckvetmanual.com)
  • This type of tumor affects men and women equally. (medlineplus.gov)
  • About one half of the people with this type of tumor do not show any symptoms. (medlineplus.gov)
  • The pathology of CHD is characterized by plaque-like deposition of fibrous tissue on valvular cusps, leaflets, papillary muscles, chordae, and ventricular walls. (karger.com)
  • His medical history was relatively unremarkable with the exception of a large but asymptomatic solitary fibrous tumor previously diagnosed, being managed conservatively. (amjcaserep.com)
  • Usually, local resection of the tumour is sufficient. (scitechnol.com)
  • However, in some situations, infiltration of the tumour requires more extensive resection of adjacent tissues. (scitechnol.com)
  • As far as possible, treatment involves complete resection as the presence of remnants of intraorbital tumour tissue after the operation carries the risk of causing recurrence of the tumour and can even undergo transformation by becoming malignant [ 3 ]. (scitechnol.com)
  • A right nephrectomy with resection of the mass demonstrated a malignant solitary fibrous tumor. (medscape.com)
  • Positron emission tomography (PET) scanning may also be useful in delineating the extent of tumor or metastases. (medscape.com)
  • There has been substantial evolution of concepts in neuroendocrine lung tumour classification. (ersjournals.com)
  • An international system of tumour classification is important for consistency in patient treatments and to provide the basis of epidemiological and biological studies. (ersjournals.com)
  • In this report, we describe a rare case of bilateral symmetric ectopic oral tonsillar tissue located at the ventral surface of the tongue along with two solitary cases arising from the floor of the mouth. (9lib.co)
  • Here we report a rare case of bilateral symmetric ectopic oral tonsillar tissue observed on the ventral surface of the tongue and two other solitary cases arising from floor of the mouth along with a review of the literature. (9lib.co)
  • adenomatoid t. a small benign t. of the male epididymis and female genital tract , consisting of fibrous tissue or smooth muscle enclosing anastomosing glandlike spaces containing acid mucopolysaccharide lined by flattened cells that have ultra-structural characteristics of mesothelial cells. (en-academic.com)
  • brown t. a mass of fibrous tissue containing hemosiderin-pigmented macrophages and multinucleated giant cells, replacing and expanding part of a bone in primary hyperparathyroidism . (en-academic.com)
  • Chest Wall Reconstruction Repair of chest wall defects caused by trauma, tumor, or chest wall deformities with the use of muscle or omentum (underlying abdominal tissue). (nursekey.com)
  • The most common soft tissue lesion in the mesentery is a desmoid tumour. (sajr.org.za)
  • Lipomas are the most common soft-tissue tumor. (medscape.com)
  • Approximately 63% of patients will have a recurrence of their tumor, of which more than half will succumb to disease progression within two years. (wikipedia.org)
  • The fibrous capsule must be removed to prevent recurrence. (medscape.com)
  • We enrolled 31 patients (17 men and 14 women) with lung cancer ( n = 7), breast cancer ( n = 5), gastric cancer ( n = 5), pancreatic cancer ( n = 3), other cancers ( n = 5), and benign tumors ( n = 6). (snmjournals.org)
  • Finally, pleural well-differentiated papillary mesotheliomas are better defined and cases with invasive foci are recognized. (nih.gov)
  • We present two clinical cases of patients aged 36 and 74 with an orbital solitary fibrous tumour (SFT). (scitechnol.com)
  • 7. Noda M, Okada Y, Maeda S, Sado T, Sakurada A, Hoshikawa Y, Endo C, Kondo T.: A Total Pleural Covering Technique in Patients with Intractable Bilateral Secondary Spontaneous Pneumothorax: Report of Five cases. (tohoku.ac.jp)
  • Recurrent somatic fusions of the two genes, NGFI-A-binding protein 2 (NAB2) and STAT6, located at chromosomal region 12q13, have been identified in solitary fibrous tumors. (wikipedia.org)
  • For recurrent, invasive tumors, more aggressive attempts at excision or electroporation may be required. (merckvetmanual.com)
  • The [ 18 F]FAPI-74 PET images were compared between the primary or local recurrent lesions of malignant tumors ( n = 21) and nonmalignant lesions ( n = 8: type-B1 thymomas, granuloma, solitary fibrous tumor, and postoperative or posttherapeutic changes). (snmjournals.org)
  • NAB2-STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors. (wikipedia.org)
  • Another useful discovery was that the NAB2-STAT6 fusion is characteristic of solitary fibrous tumors. (nih.gov)
  • Solitary fibrous tumors are rare tumors of primarily mesenchymal origin with isolated instances of epithelial origin [3]. (amjcaserep.com)
  • CT is the imaging modality of choice to assess pleural disease and has shown sensitivity and specificity for identifying malignancy. (medscape.com)
  • Video-assisted thoracoscopic surgery (VATS) is being used to treat esophageal submucosal tumors (SMTs) all over the world. (omicsdi.org)
  • In the GI tract, lipomas present as submucosal fatty tumors. (medscape.com)
  • [ 5 ] An earlier report, in 1956, by Babolini and Blasi, described the same clinicopathological entity using the nomenclature, "The pleural form of primary cancer of the lung. (medscape.com)
  • This led to development of a STAT6 antibody that is a reliable immunohistochemical marker for solitary fibrous tumors. (nih.gov)
  • SFTs have also been known as hemangiopericytomas although this term has now been discontinued from WHO tumor classifications. (wikipedia.org)
  • reticulum cell sarcomas, cutaneous nodular amyloidosis) are relatively common cutaneous tumors. (merckvetmanual.com)
  • Could microsatellite analysis of pleural fluid increase sensitivity of pleural fluid cytology? (ers-education.org)
  • Assessing the role of pleural fluid in current cancer diagnostic pathway. (ers-education.org)
  • however, MRI was found to be more accurate in detecting solitary foci of chest wall invasion and endothoracic fascia involvement and in assessing invasion of the diaphragm. (medscape.com)
  • Carcinoid heart disease (CHD) is a rare and potentially lethal manifestation of an advanced carcinoid (neuroendocrine) tumor. (karger.com)