Splenic Infarction
Splenic Artery
Dermatomyositis with splenic and renal infarctions during corticosteroid therapy. (1/41)
A 60-year-old woman was admitted to our hospital with complaints of muscle weakness and erythema on her extremities. Gottron's sign, heliotrope rash, elevation of serum myogenic enzymes, electromyography and magnetic resonance imaging findings established a diagnosis of dermatomyositis (DM). She was treated with 60 mg of daily prednisolone. One week later, she suddenly developed splenic and renal infarctions, which were considered to have resulted from vasculopathy associated with DM. Cyclophosphamide and anticoagulants along with increasing the dosage of corticosteroid were effective. This is the first report describing splenic and renal infarctions in a patient with adult-onset DM. (+info)Thermophilic multidrug-resistant Campylobacter fetus infection with hypersplenism and histiocytic phagocytosis in a patient with acquired immunodeficiency syndrome. (2/41)
We present a case report of a patient who had acquired immunodeficiency syndrome (AIDS) and Campylobacter fetus infection with a number of unusual clinical and microbiological features. The patient had prominent gastrointestinal symptoms, splenic infarction, splenomegaly with hypersplenism, and hemophagocytic histiocytosis in the spleen and lymph nodes; the organism displayed growth on Campy-selective blood agar, thermotolerance, and resistance to quinolones, piperacillin/tazobactam, ceftazidime, and erythromycin. (+info)Acute cytomegalovirus infection complicated by vascular thrombosis: a case report. (3/41)
We present a case report of a previously healthy adult with cytomegalovirus infection that was complicated by extensive mesenteric arterial and venous thrombosis. To our knowledge, this is the first reported case of this syndrome in an immunocompetent individual who had no predisposing risk factors for thrombosis, and it demonstrates the propensity for cytomegalovirus to be involved in vascular disease. (+info)Splenic accumulation of 99mTc-diphosphonate in a patient with sickle cell disease: case report. (4/41)
Splenic accumulation of 99mTc-diphosphonate is shown in the bone scan of a patient with sickle cell disease. This uptake is assumed to result from splenic infarction and subsequent calcification. The conventional liver-spleen scan with 99mTc-sulfur colloid shows no splenic activity, and a radiograph shows calcification in the left upper quadrant of the abdomen in the expected anatomic location of the spleen. (+info)Asian variant of CD5+ intravascular large B-cell lymphoma with splenic infarction. (5/41)
A 57-year-old man was admitted with fever and epigastralgia, and presented with splenomegaly and pancytopenia. A CT scan revealed splenic infarctions. There were no lymphadenopathies, skin lesions, or neurological abnormalities. A splenectomy was performed. Bone marrow involvement with hemophagocytosis was noted. The diagnosis of Asian variant of intravascular diffuse large B-cell lymphoma was based on intravascular and sinusoidal distribution of large CD5+ B cells. The patient died of the disease 11 months after onset. To our knowledge, this is the first report of AIVL that presented with splenic infarction. This distinct lymphoma should be included in the differential diagnosis of splenic infarction. (+info)Splenic infarction following laparoscopic Nissen fundoplication: management strategies. (6/41)
Techniques for mobilizing the greater curve of the stomach during laparoscopic Nissen fundoplication (LNF) include division of the short gastric vessels (SGV). The splenic artery and vein lie directly posterior to the proper plane of dissection. Uncontrolled bleeding during SGV division places the splenic vessels at risk for inadvertent injury or ligation. We report herein on 2 patients referred to our institution who had left upper quadrant pain and radiographic evidence of segmental splenic infarction (SI) that resulted from a peripheral splenic artery branch injury during LNF. Management strategies included a trial of conservative management and splenectomy for persistent symptoms or complications resulting from SI. Intense inflammation and adhesion formation making laparoscopic splenectomy difficult should be anticipated when operating on the infarcted spleen. (+info)Torted and ruptured wandering spleen presenting as a surgical emergency in pregnancy. (7/41)
Wandering spleen (WS) is characterised by incomplete fixation of the spleen to its supporting linorenal and gastrosplenic ligaments. It can predispose to life-threatening complications due to torsion of its vascular pedicle, splenic infarction, portal hypertension, and haemorrhage. A 27-year-old, 36-week prima gravida underwent emergency caesarean section for tachycardia and hypotension. A healthy baby girl was delivered. However, she remained shocked despite aggressive fluid therapy and intraoperatively it was noted that there was significant intraperitoneal bleeding and the on-call surgical team was summoned. Midline laparotomy revealed a lacerated, infarcted, hypermobile spleen found with free intraperitoneal bleeding. The unsalvageable spleen was resected and the patient went on to make an excellent recovery. The aetiology of WS is contentious. With an increased frequency among multiparous females of reproductive age, some suggest the hormonal effects of pregnancy as contributing factors. Clinical presentations range from an asymptomatic abdominal mass to acute abdominal pain with hypovolaemic shock. WS poses a serious threat to life due to thrombosis, bleeding, or infarction. Ultrasound scan and CT scan are equally effective in the diagnosis. Patients with asymptomatic WS should be treated with elective splenopexy, however, in the acute presentation, splenectomy is the procedure of choice. (+info)Splenic syndrome in patients at high altitude with unrecognized sickle cell trait: splenectomy is often unnecessary. (8/41)
BACKGROUND: The health risks associated with sickle cell trait are minimal in this sizable sector of the world's population, and many of these patients have no information about their sickle cell status. Splenic syndrome at high altitude is well known to be associated with sickle cell trait, and unless this complication is kept in mind these patients may be subjected to unnecessary surgery when they present with altitude-induced acute abdomen. METHODS: Four patients were admitted to the surgical ward with a similar complaint of acute severe left upper abdominal pain after arrival to the mountainous resort city of Abha, Saudi Arabia. All were subjected to splenectomy because of lack of suspicion regarding sickle cell status. RESULTS: Histologic examination of the spleen showed all patients had sickle cells in the red pulp. On further assessment all were found to have sickle cell trait with splenic infarction. In a similar study of 6 patients with known sickle cell disease who had comparable problems when they travelled to the Colorado mountains, all made an uncomplicated recovery with conservative management. CONCLUSIONS: In ethnically vulnerable patients with splenic syndrome, sickle cell trait should be ruled out before considering splenectomy. These patients could respond well to supportive management, and splenectomy would be avoided. (+info)Splenic infarction is the death of splenic tissue due to blockage of its arterial supply or, less commonly, its venous drainage. This results in ischemia and necrosis of the affected portion of the spleen. The most common cause is embolism from a distant source such as atrial fibrillation, infective endocarditis, or malignancy. Other causes include splenic artery thrombosis, sickle cell disease, hematologic disorders, and trauma. Clinical presentation can vary widely, ranging from being asymptomatic to acute abdominal pain, nausea, vomiting, and fever. Diagnosis is often made with imaging studies such as ultrasound or CT scan. Treatment depends on the underlying cause and severity of symptoms, but may include anticoagulation, antibiotics, or surgical intervention in severe cases.
The splenic artery is the largest branch of the celiac trunk, which arises from the abdominal aorta. It supplies blood to the spleen and several other organs in the upper left part of the abdomen. The splenic artery divides into several branches that ultimately form a network of capillaries within the spleen. These capillaries converge to form the main venous outflow, the splenic vein, which drains into the hepatic portal vein.
The splenic artery is a vital structure in the human body, and any damage or blockage can lead to serious complications, including splenic infarction (reduced blood flow to the spleen) or splenic rupture (a surgical emergency that can be life-threatening).
A splenectomy is a surgical procedure in which the spleen is removed from the body. The spleen is an organ located in the upper left quadrant of the abdomen, near the stomach and behind the ribs. It plays several important roles in the body, including fighting certain types of infections, removing old or damaged red blood cells from the circulation, and storing platelets and white blood cells.
There are several reasons why a splenectomy may be necessary, including:
* Trauma to the spleen that cannot be repaired
* Certain types of cancer, such as Hodgkin's lymphoma or non-Hodgkin's lymphoma
* Sickle cell disease, which can cause the spleen to enlarge and become damaged
* A ruptured spleen, which can be life-threatening if not treated promptly
* Certain blood disorders, such as idiopathic thrombocytopenic purpura (ITP) or hemolytic anemia
A splenectomy is typically performed under general anesthesia and may be done using open surgery or laparoscopically. After the spleen is removed, the incision(s) are closed with sutures or staples. Recovery time varies depending on the individual and the type of surgery performed, but most people are able to return to their normal activities within a few weeks.
It's important to note that following a splenectomy, individuals may be at increased risk for certain types of infections, so it's recommended that they receive vaccinations to help protect against these infections. They should also seek medical attention promptly if they develop fever, chills, or other signs of infection.
Sickle cell trait is a genetic condition where an individual inherits one abnormal gene for hemoglobin S (HbS) from one parent and one normal gene for hemoglobin A (HbA) from the other parent. Hemoglobin is a protein in red blood cells that carries oxygen throughout the body.
People with sickle cell trait do not have sickle cell disease, but they can pass the abnormal HbS gene on to their children. In certain situations, such as high altitude, low oxygen levels, or intense physical exertion, individuals with sickle cell trait may experience symptoms similar to those of sickle cell disease, such as fatigue, pain, and shortness of breath. However, these symptoms are typically milder and less frequent than in people with sickle cell disease.
It is important for individuals who know they have sickle cell trait to inform their healthcare providers, especially if they become pregnant or plan to engage in activities that may cause low oxygen levels, such as scuba diving or high-altitude climbing.
Splenic infarction
Infarction
Abdominal angina
Spleen pain
Spleen
Splenomegaly
Leprostatic agent
Neutrophil
Classical swine fever
Beta thalassemia
Wandering spleen
Ryan Clark (American football)
Haematopoiesis
Asymptomatic
List of MeSH codes (C15)
Torsion
List of MeSH codes (C14)
Acute pancreatitis
Embolization
Splenosis
Anaerobic infection
Watershed area (medical)
End artery
Ischemic colitis
Acute abdomen
Superior mesenteric artery
Interventional radiology
Canine histiocytic diseases
Cold shock response
Sickle cell disease
Splenic infarction - Wikipedia
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Massive Splenic Infarction Abscess in A Teenager with Sickle Cell Disease: A Case Report in Northern Benin
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Splenic Infarct: Background, Anatomy, Pathophysiology
Spleen20
- Splenic infarction is a condition in which blood flow supply to the spleen is compromised, leading to partial or complete infarction (tissue death due to oxygen shortage) in the organ. (wikipedia.org)
- In sickle cell disease, repeated splenic infarctions lead to a non-functional spleen (autosplenectomy). (wikipedia.org)
- Examples include abdominal traumas, aortic dissection, torsion of the splenic artery (for example, in wandering spleen) or external compression on the artery by a tumor. (wikipedia.org)
- Splenic infarction is the death of tissue (necrosis) in the spleen due to a blockage in blood flow. (medlineplus.gov)
- Splenic infarction is a result of ischemia to the spleen , and in many cases requires no treatment. (radiopaedia.org)
- Splenic infarcts can occur due to a number of processes, involving either arterial supply, the spleen itself or the venous drainage. (radiopaedia.org)
- In cases of torsion of a wandering spleen, splenopexy with splenic salvage is the procedure of choice in the well-perfused, noninfarcted spleen. (medscape.com)
- Whereas a unilocular abscess can be managed successfully in select cases with percutaneous catheter drainage, some authors advocate splenectomy in all cases of splenic infarct and abscess, questioning the utility of preserving the residual, partially functioning spleen. (medscape.com)
- Intraoperative ligation of the splenic artery at the superior margin of the pancreas in the lesser sac is another alternative to minimize blood loss if the spleen is enlarged. (medscape.com)
- Changes in spleen structure, frequently encountered during malaria, may result either in a simple asymptomatic enlargement or in serious complications such as hematoma, rupture, or infarction ( 1 - 3 ). (cdc.gov)
- Hematoma or infarction of the spleen might be followed by the development of a splenic abscess, a clinical condition that has been reported in only 1 patient, to our knowledge ( 4 ). (cdc.gov)
- An enlarged spleen is found in 50% to 80% of malaria patients ( 1 ), while only 25 cases of splenic rupture have been reported since 1960 (0%-2% in natural occurring infection) ( 5 ). (cdc.gov)
- Spleen infarction is rarer than rupture and may go unnoticed. (cdc.gov)
- Indeed, splenic hematoma or infarction, together with the humoral and cellular immunodepression due to malaria, might well be predisposing factors for bacterial (e.g., salmonellae) colonization of the spleen from the gut, as likely happened in this patient, although cultures of the pus, blood, or intraabdominal fluid were not performed. (cdc.gov)
- The arterial supply to the spleen consists of the splenic artery (a branch of the celiac axis) and the short gastric arteries (branches of the left gastroepiploic artery), which supply the upper pole of the spleen. (medscape.com)
- Most commonly, these infarcts contract and fibrose over time, as demonstrated by the sickle hemoglobinopathies (in which repeated episodes of infarction ultimately result in autoinfarction of the spleen). (medscape.com)
- The spleen, sometimes called "the forgotten organ" of the abdomen, has received less attention than other abdominal solid organs, as splenic diseases are less common and frequently clinically asymptomatic [ 1 ]. (e-ultrasonography.org)
- Accessory spleen, which results from a failure of the embryonic splenic anlage to fuse and extreme lobulation that separates splenic tissue, is a normal variant observed in 10%-30% of individuals [ 7 ]. (e-ultrasonography.org)
- Computed tomography scan displayed a hypodense spleen lesion suggestive of splenic infarction. (farabiretina.com)
- The splenic artery supplies blood to the spleen. (medscape.com)
Artery6
- Splenic infarction occurs when the splenic artery or one of its branches are occluded, for example by a blood clot. (wikipedia.org)
- Any factor that directly compromises the splenic artery can cause infarction. (wikipedia.org)
- Patients underwent baseline angiography of the celiac trunk, superior mesenteric artery, hepatic artery, and splenic artery using a peripheral arterial approach. (hindawi.com)
- Even with occlusion of the main splenic artery, collateral flow from the short gastric arteries often may preserve some or all of the splenic parenchyma. (medscape.com)
- These include coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular tachycardia and ventricular fibrillation. (ncats.io)
- Its terminal branches aside, the splenic artery also gives off branches to the pancreas, 5-7 short gastric branches, and the left gastro-omental (gastroepiploic) artery (see the image below). (medscape.com)
Abscess11
- Agbeille Mohamed F, Hadonou AA, Noudamadjo A, Kpanidja MG, Doha F, Adédémy JD, Agossou J. Massive Splenic Infarction Abscess in A Teenager with Sickle Cell Disease: A Case Report in Northern Benin. (asploro.com)
- Splenic abscess is rare in children. (asploro.com)
- This report discusses a case of splenic abscess complicating an infarction in a teenager at the Teaching Hospital of Borgou/Alibori in Benin Republic. (asploro.com)
- Abdominal ultrasound and thoraco-abdominal CT-scan revealed a splenic infarction abscess. (asploro.com)
- Splenic abscess should be suspected in any subject with sickle cell disease presenting with painful and febrile splenomegaly. (asploro.com)
- Splenic abscess can result from septic emboli or superinfection of a prior infarct. (medscape.com)
- [ 4 ] In certain circumstances, isolated splenic abscess can be treated with percutaneous drainage alone, and splenectomy can be avoided. (medscape.com)
- two of the cases were associated with a mycotic aneurysm, and one case was associated with a splenic abscess. (biomedcentral.com)
- The third patient had a splenic infarction and abscess associated with infected cardiac thrombi. (biomedcentral.com)
- two were associated with MA, and one was associated with splenic abscess. (biomedcentral.com)
- Acute splenic tenderness indicates splenic infarction or abscess formation. (medicosnotes.com)
Acute myocardial1
- [ 4 ] Splenic embolization may result from various cardiovascular conditions, including a left atrial or ventricular mural thrombus that formed as a result of acute myocardial infarction or atrial fibrillation or developed from complications of cardiac catheterization or bacterial endocarditis. (medscape.com)
Infarct5
- The appearance of splenic infarction depends on the timing of imaging and the size of the infarct. (radiopaedia.org)
- Morphologically the typical infarct is of a pyramidal wedge of affected splenic tissue with the apex pointing towards the hilum, and the base on the splenic capsule. (radiopaedia.org)
- We report the case of splenic infarct secondary to embolisation from a polypoid 17 mm x 10 mm thoracic aorta thrombi in a 60 year-old female. (edu.au)
- Another mechanical cause of splenic infarct can be the injection of gastric varices in the setting of portal hypertension and gastric variceal bleeding. (medscape.com)
- Splenic infarct has also been reported in association with postpartum toxic shock syndrome. (medscape.com)
Myocardial3
- Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. (rxlist.com)
- Myocardial ischemia/infarction and Prinzmetal's angina: Perform cardiac evaluation in patients with multiple cardiovascular risk factors. (nih.gov)
- Impact of Beta Blockers on Left Ventricular Reverse Remodeling Following Primary Coronary Intervention for ST-elevation Myocardial Infarction. (imed.pub)
Embolization2
- We retrospectively evaluated the long-term effects of partial splenic embolization (PSE) with transarterial chemoembolization (TACE) in patients with HCC patients accompanied by thrombocytopenia. (hindawi.com)
- Over the past 20 years, partial splenic embolization (PSE) has been an interventional radiological treatment for thrombocytopenia due to hypersplenism [ 3 , 4 ]. (hindawi.com)
Vascular1
- Splenic infarction refers to occlusion of the splenic vascular supply, leading to parenchymal ischemia and subsequent tissue necrosis. (medscape.com)
Sickle Cell A2
- Splenic infarction can also result from a sickle cell crisis in patients with sickle cell anemia. (wikipedia.org)
- Splenic infarctions are common in sickle cell anemia patients (SCA). (biogossip.com)
Vein3
- Splenic vein thrombosis, most commonly the result of pancreatitis or surgery, can result in venous infarction. (medscape.com)
- A CT revealed a splenic infarction with splenic vein thrombosis and a 2 cm mass of the pancreatic tail. (egeus.org)
- C-4: Splenic vein thrombosis of the same patient is marked by arrows. (medscape.com)
Cases of splenic1
- Only 9 documented cases of splenic infarction associated with malaria have been reported ( 3 ), all consequent to P . falciparum infection (except in 1 patient who was coinfected with P . vivax and 2 cases in which the etiologic agent was unknown). (cdc.gov)
Incidence of splenic1
- The incidence of splenic hematoma without rupture is unknown ( 2 ). (cdc.gov)
Segmental1
- As technologies evolve, laparoscopic splenic preservation may become the future standard of care for segmental infarcts. (medscape.com)
Diagnosis of acute1
- In a single-center retrospective cases review, people who were admitted to the hospital with a confirmed diagnosis of acute splenic infarction, cardiogenic emboli was the dominant etiology followed by atrial fibrillation, autoimmune disease, associated infection, and hematological malignancy. (wikipedia.org)
Malaria1
- Splenic infarction and malaria. (nih.gov)
Rupture3
- Missed splenic rupture or delayed diagnosis is associated with a 10-fold increase in mortality over the rate associated with prompt recognition of injury. (medscape.com)
- A break of a contained hematoma is usually involved in splenic rupture, which occurs almost exclusively during acute infection and the primary attack ( 6 ). (cdc.gov)
- Splenic rupture following infarction has not yet been described. (cdc.gov)
Tissue2
- multiple infarcts appear as hypodense non-enhancing lesions, with normal intervening enhancing splenic tissue. (radiopaedia.org)
- On histologic examination, splenic tissue was found to have been replaced by congested inflammatory infiltrates and fibrotic tissue. (cdc.gov)
Abdominal2
- The classic presentation of splenic injury includes hemodynamic instability, severe abdominal pain, and symptoms of peritonitis. (medscape.com)
- Therefore, US is widely used and frequently chosen as the first imaging modality for most abdominal imaging, both for general abdominal examinations and for patients suspected of having splenic diseases. (e-ultrasonography.org)
Computed Tomography3
- The American Association for the Surgery of Trauma (AAST) splenic injury scale is based on computed tomography (CT) findings, as follows. (medscape.com)
- in almost half of the patients with infarction, the diagnosis was made incidentally on computed tomography (CT). (medscape.com)
- Therefore, this pictorial essay elucidates the US findings of various splenic lesions, in correlation with computed tomography (CT) or magnetic resonance (MR) imaging and pathology. (e-ultrasonography.org)
Granulomatosis with polyangiitis1
- Various other conditions have been associated with splenic infarction in case reports, for example granulomatosis with polyangiitis or treatment with medications that predispose to vasospasm or blood clot formation, such as vasoconstrictors used to treat esophageal varices, sumatriptan or bevacizumab. (wikipedia.org)
Splenectomy5
- However, a patient with multiple splenic abscesses usually will require splenectomy. (medscape.com)
- Complications, such as bleeding or pseudocyst formation, also may be amenable to splenic salvage using techniques of partial splenectomy. (medscape.com)
- As laparoscopic techniques become more advanced, many of the surgical problems associated with splenic infarction certainly will prove amenable to laparoscopic splenectomy or partial splenectomy. (medscape.com)
- Eight (3%) of the 271 children required splenectomy (1 after the initial episode of ASSC, 3 after a second episode of ASSC, 2 as a result of pain accompanying chronic infarction and ASSC, and 2 because of splenic hemorrhage). (elsevierpure.com)
- Repeated splenic infarction may be an indication for splenectomy. (medicosnotes.com)
Complications4
- [ 12 ] Complications of splenic infarction were a frequent indication (60%) for operation in patients with septic emboli. (medscape.com)
- Objective: To determine the frequency and severity of acute splenic complications in children and adolescents with sickle cell (SC) hemoglobin C disease. (elsevierpure.com)
- Results: Sixteen (6%) children had acute splenic complications. (elsevierpure.com)
- Conclusions: We conclude that (1) acute splenic complications in children and adolescents with SC disease are relatively uncommon, (2) most episodes of ASSC occur in preadolescents, (3) ASSC can be life threatening, even in younger children, and (4) prior splenomegaly is not a good predictor of ASSC. (elsevierpure.com)
Occurs2
- If liquefaction occurs, the area may be rounded and anechoic ( splenic pseudocyst ). (radiopaedia.org)
- A third mechanism for splenic trauma is explosive-type injuries, such as occurs in warfare and civilian bombing. (medscape.com)
Patient2
- Hypotension in a patient with a suspected splenic injury can be a grave sign and a surgical emergency. (medscape.com)
- C-6: Ultrasound image of the same patient showing a larger infarction/collection? (medscape.com)
Hilum2
- It is usually found around the splenic hilum or ligaments, pancreatic tail, or sometimes in the pancreatic parenchyma [ 7 ]. (e-ultrasonography.org)
- The hilum transmits the splenic vessels and nerves and provides attachment to the gastrosplenic and splenorenal (lienorenal) ligaments. (medscape.com)
Asymptomatic1
- It should be noted that ~40% (range 30-50%) of patients with splenic infarction are asymptomatic 9 . (radiopaedia.org)
Clinical1
- Knowledge of the US features of various splenic lesions will help narrow the differential diagnosis and guide clinical decision-making. (e-ultrasonography.org)
Lesions3
- Concomitantly with the increasing frequency of imaging, more splenic lesions are being discovered and the requirements for the differential diagnosis are rising. (e-ultrasonography.org)
- In this pictorial essay, we introduce the representative US findings of many different splenic lesions, including normal sonographic findings, normal variants and congenital anomalies, infectious conditions, benign and malignant neoplasms, and non-neoplastic lesions. (e-ultrasonography.org)
- However, with the increasing frequency of imaging and advances in imaging technology, more incidental splenic lesions are being discovered and the subsequent requirements for the differential diagnosis are growing. (e-ultrasonography.org)
Surgery1
- Splenic infarction alone is not an indication for surgery. (medscape.com)
Hemorrhagic1
- In the hyperacute phase, CT may show areas of mottled increased attenuation, representing areas of a hemorrhagic infarction. (radiopaedia.org)
Diseases3
- Infiltrative hematologic diseases cause congestion of the splenic circulation by abnormal cells. (medscape.com)
- In malignant hematologic diseases (eg, chronic myeloid leukemia), increased splenic oxygen requirements secondary to an increased splenic mass, coupled with a decreased oxygen-carrying capacity secondary to the anemia of hypersplenism, lead to infarction. (medscape.com)
- However, to the authors' knowledge, there are not enough up-to-date ultrasonographic imaging reviews of splenic diseases [ 2 - 5 ]. (e-ultrasonography.org)
Preservation2
- Because of the (admittedly small) risk of fatal OPSS, splenic preservation is preferable whenever possible. (medscape.com)
- There is great interest regarding the extension of the safe indications for splenic preservation. (medscape.com)
Surgical1
- In fact, overall, most splenic infarcts do not require surgical intervention. (medscape.com)
Hemoglobinopathies1
- Other causes of splenomegaly (for example, Gaucher disease or hemoglobinopathies) can also predispose to infarction. (wikipedia.org)
Patients3
- Patients with a splenic infarction may present with left upper quadrant pain. (radiopaedia.org)
- A FAST exam should be instituted in hemodynamically unstable patients with splenic trauma to assess the degree of both trauma and bleeding. (medscape.com)
- Three additional patients had a history of acute painful splenic infarction, two of whom also had splenic hemorrhage. (elsevierpure.com)
Vasculitis1
- Splenic infarction can be due to vasculitis or disseminated intravascular coagulation. (wikipedia.org)
Vessels1
- it contains the tail of the pancreas and splenic vessels. (medscape.com)
Oxygen1
- In individuals who are heterozygous for sickle trait, exposure to low-oxygen tension (eg, during unpressurized airplane travel) or vigorous activity (eg, skiing in high-altitude locations) can precipitate sickling and splenic infarction by the above-described mechanism. (medscape.com)
Circulation2
- [ 3 ] In myelofibrosis, the splenic parenchyma is infiltrated by extramedullary hematopoiesis, causing congestion of the splenic circulation. (medscape.com)
- The splenic circulation is adapted for the separation and storage of the red blood cells. (medscape.com)
Common4
- Splenic infarction is also more common in hematological disorders with associated splenomegaly, such as the myeloproliferative disorders. (wikipedia.org)
- Infectious Mononucleosis-Induced Splenic Infarction: Perhaps More Common in Healthy Individuals Than Previously Thought. (hcahealthcare.com)
- Mamo G, Erickson S, Komanduri K, Zayas D, Aggarwal N. Infectious Mononucleosis-Induced Splenic Infarction: Perhaps More Common in Healthy Individuals Than Previously Thought. (hcahealthcare.com)
- Thromboembolism is another common cause of splenic infarcts. (medscape.com)