Splenosis
Intrahepatic splenosis in a dog. (1/29)
A 10-year-old castrated male Standard Poodle presented with an acute onset of lethargy and abdominal pain. The animal had a history of traumatic splenic rupture requiring splenectomy 5 years previously. Surgical exploration revealed multiple cystic red nodules involving all liver lobes, several of which were submitted for histopathology. Microscopically, the cystic nodules were dilated bile ducts and lymphatics surrounded by ectopic splenic tissue. A diagnosis of intrahepatic splenosis was made. (+info)Hepatic splenosis misinterpreted as hepatocellular carcinoma in cirrhotic patients referred for liver transplantation: report of two cases. (2/29)
Liver transplantation is one of the main therapeutic options for hepatocellular carcinoma (HCC) occurring in cirrhotic patients; an accurate diagnosis and staging of this cancer is crucial to selecting the candidates for this treatment. Although the best diagnostic strategy is debated, the guidelines proposed by the European Association for the Study of the Liver (EASL) are used by many centers. We report 2 cases of cirrhotic patients with hepatic splenosis, a rare condition that may be misinterpreted as HCC. In conclusion, the application of the EASL guidelines in the first case would have led to an incorrect staging of the cancer and in the second case would have led to a false diagnosis of HCC. (+info)Solitary ovarian splenosis. (3/29)
This report describes the case of an asymptomatic, solitary splenotic nodule in the right ovary, revealed incidentally at histopathological examination. In gynaecological patients, splenosis most often presents as multiple pelvic nodules mimicking endometriosis. Two cases of ovarian splenosis accompanying pelvic and serosal splenotic nodules have been reported previously. However, this is the first documented case of solitary intraovarian splenosis. (+info)Diagnostic difficulties of pelvic splenosis: case report. (4/29)
We report the case of a 38-year-old woman who presented with chronic lower abdominal pain. Her past medical history included a splenectomy due to abdominal trauma. Ultrasound examination revealed four pelvic tumors which, upon laparotomy, were found to be the result of splenosis. Approximately 100 cases of splenosis have been reported but only a minority of them have been published in the gynecological literature. Our case indicates that those involved in pelvic scanning (even of asymptomatic women) and/or treating those complaining of lower abdominal pain or presenting with pelvic tumors should be aware of splenosis as a possible diagnosis. (+info)Intrathoracic splenosis secondary to previous penetrating thoracoabdominal trauma diagnosed during delayed diaphragmatic hernia repair. (5/29)
Although intraperitoneal splenosis is a very common disease, intrathoracic splenosis is very rare. It is generally an asymptomatic disease that occurs after thoracoabdominal trauma, and is diagnosed as an intrathoracic mass that leads to unnecessary investigations to be differentiated from other benign or malignant lesions of the chest. We present a patient with an intrathoracic mass which was preoperatively diagnosed as a diaphragmatic hernia on chest X-ray and magnetic resonance imaging. We have intraoperatively recognized that many pieces of splenic tissue have been herniated through a diaphragmatic defect, and formed intrathoracic splenosis. We repaired the diaphragmatic hernia defect after excision of fragments of the spleen. (+info)Rare cause of pleural nodularity: Splenosis. (6/29)
Splenosis is a rare condition described as ectopic splenic tissue implantation generally after a splenic rupture. A 35-year-old male patient who had a history of splenectomy operation due to gunshot wound seven years ago was referred to our hospital with complaints, including exhaustion, sweating and shortness of breath. Thoracic computed tomography of the patient showed nodular pleural thickenings at the level of the left lower lobe, which proved to be unrelated with the presenting symptoms. The patient underwent a minithoracotomy for diagnosis and treatment. During the intraoperative observation, dark-colored, soft, multiple nodular lesions with a biggest size of 2 cm inside the visceral pleura over an area of 5 x 10 cm in dimension were observed. Also, a few tiny nodules in the lung parenchyma approximately 1-cm deep to the pleural nodules were palpated. The lesions were excised. The histopathological examination of the specimen showed splenic tissue in the lung parenchyma and pleura, so the lesions were accepted as splenosis. Pleuropulmonary splenosis, which develops generally after simultaneous rupture of the diaphragma and spleen, is a very rare condition. Most of the patients are asymptomatic and the lesions are detected accidentally. If the diagnosis can be made preoperatively, surgical excision is not needed. (+info)Mistletoe lectin (Viscum album coloratum) modulates proliferation and cytokine expressions in murine splenocytes. (7/29)
It is well documented that an extract of European mistletoe has a variety of biological effects, such as the stimulation of cytokine production from immune cells, and additional immunoadjuvant activities. While the European mistletoe has been studied intensively, we know less about Korean mistletoe as a therapeutic plant, especially as a possible immunomodulating drug. This study will investigated the effects of Korean mistletoe lectin (Viscum album L. var. coloratum agglutinin, VCA) on murine splenocytes to investigate whether VCA acts as an immunomodulator, which could lead to improved immune responses in these cells. The results showed that VCA inhibited cell proliferation at higher concentrations (at 1-8 ng/ml) and enhanced cell proliferation at lower concentrations (at 4-32 pg/ml). Further studies were carried out to determine if the proproliferative or anti-proliferative activity exhibited by VCA was correlated with cytokine secretion. Consequently, interferon (IFN)-gamma secretion was decreased in concanavalin A (ConA)-stimulated murine splenocytes by VCA (4-64 ng/ml), but there was no change in IL-4 levels. This suggests that VCA has the ability to modulate murine splenocyte proliferation and can possibly act on the balance of Th1/Th2 cellular immune responses. (+info)Splenosis. A diagnosis to be considered. (8/29)
The term splenosis applies to the autotransplanted splenic tissue resulting from seeding in the context of past splenic trauma or surgery. We report a 42-year-old man with a history of splenectomy observed for an incidentally found retrovesical mass thought to be an ectopic testicle. The abdominal laparotomy revealed multiple focuses of pelvic splenosis. As splenosis can be diagnosed through specific imaging studies one should always consider it in differential diagnosis of a mass discovered years after splenic surgery or trauma. (+info)Splenosis is a benign condition characterized by the implantation and growth of ectopic splenic tissue, usually following trauma or surgery that results in splenic rupture. The displaced splenic tissues, known as splenunlai, develop functional microvascular structures and can grow in various locations within the abdominal cavity, chest, or other sites. These nodules typically appear 4-6 years after the initial injury but may take up to 20 years to develop. Splenosis is often an incidental finding during medical imaging or surgical procedures, and no specific treatment is required unless complications arise, such as intestinal obstruction or malignancy suspicion.
A splenectomy is a surgical procedure in which the spleen is removed from the body. The spleen is an organ located in the upper left quadrant of the abdomen, near the stomach and behind the ribs. It plays several important roles in the body, including fighting certain types of infections, removing old or damaged red blood cells from the circulation, and storing platelets and white blood cells.
There are several reasons why a splenectomy may be necessary, including:
* Trauma to the spleen that cannot be repaired
* Certain types of cancer, such as Hodgkin's lymphoma or non-Hodgkin's lymphoma
* Sickle cell disease, which can cause the spleen to enlarge and become damaged
* A ruptured spleen, which can be life-threatening if not treated promptly
* Certain blood disorders, such as idiopathic thrombocytopenic purpura (ITP) or hemolytic anemia
A splenectomy is typically performed under general anesthesia and may be done using open surgery or laparoscopically. After the spleen is removed, the incision(s) are closed with sutures or staples. Recovery time varies depending on the individual and the type of surgery performed, but most people are able to return to their normal activities within a few weeks.
It's important to note that following a splenectomy, individuals may be at increased risk for certain types of infections, so it's recommended that they receive vaccinations to help protect against these infections. They should also seek medical attention promptly if they develop fever, chills, or other signs of infection.
Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) is a medical procedure that combines the use of endoscopy and ultrasound to guide the fine needle aspiration biopsy of internal organs or lesions. This technique allows for the sampling of tissue from inside the gastrointestinal tract and adjacent organs such as the pancreas, lymph nodes, and liver.
During the procedure, an endoscope equipped with an ultrasound probe is inserted through the patient's mouth and advanced to the area of interest. The ultrasound probe provides real-time images of the internal organs and lesions, allowing the physician to guide the fine needle into the target tissue. Once the needle is in position, suction is applied to collect a sample of cells or fluid for further examination under a microscope.
EUS-FNA is commonly used to diagnose and stage various types of cancer, as well as to evaluate other conditions such as pancreatitis, chronic liver disease, and gastrointestinal submucosal tumors. The procedure is generally safe and well-tolerated, with minimal risks and complications. However, as with any medical procedure, there are potential risks and benefits that should be discussed with a healthcare provider before undergoing EUS-FNA.
Splenosis
Accessory spleen
Tumor-like disorders of the lung pleura
Spleen transplantation
Spleen
Omental cake
List of MeSH codes (C15)
List of MeSH codes (C21)
Splenosis - Wikipedia
Splenosis | Quick Answers Surgery | AccessSurgery | McGraw Hill Medical
Intra-abdominal splenosis mimicking metastatic cancer<...
Thoracic Splenosis - Polish Journal of Surgery - Volume 81, Issue 11 (2009) - PSJD - Yadda
Pediatric Asplenia: Practice Essentials, Background, Pathophysiology
Archivos de Bronconeumología
Symptomatic Heterotopic Splenic Tissue in the Left Renal Fossa | European Urology | Karger Publishers
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Where are accessory spleens found? - Bloodraynebetrayal.com
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Evaluation of a Patient For Residual Splenic Tissue Following Splenectomy | Medicalalgorithms.com
International Journal of Pediatrics - Articles List
Serological Survey for Ehrlichia canis in Dogs From the Mediterranean Coast of Turkey - WSAVA2002 - VIN
Thoracic13
- Single case reports also describe splenosis in the thoracic cavity, in subcutaneous tissue, in the liver or in the cranial cavity. (wikipedia.org)
- Splenosis in the thoracic cavity is rarer, because it requires the simultaneous rupture of the diaphragm. (wikipedia.org)
- Symptoms of splenosis affecting the thoracic cavity sometimes include hemoptysis or pleurisy. (wikipedia.org)
- A. H. Huang, K. Shaffer: Case 93: thoracic splenosis. (wikipedia.org)
- J. N. Yammine, A. Yatim, A. Barbari: Radionuclide imaging in thoracic splenosis and a review of the literature. (wikipedia.org)
- Huang AH, Shaffer K: Case 93: thoracic splenosis. (edu.pl)
- Buchino JJ, Buchino JJ: Thoracic splenosis. (edu.pl)
- Bizekis CS, Pua B, Glassman LR: Thoracic splenosis: mimicry of a neurogenic tumor. (edu.pl)
- Subcutaneous splenosis: a clue to diagnosis of thoracic splenosis. (edu.pl)
- McKeen S, Dharsono F: Thoracic splenosis: diagnosis of a case based on history and computerized tomography. (edu.pl)
- Miller JS, Nunez A, Espada R: Thoracic splenosis 25 years after gunshot wound to the abdomen. (edu.pl)
- Singh P, Munn NJ, Patel HK: Thoracic splenosis. (edu.pl)
- Thoracic splenosis: A diagnosis by history and imaging. (edu.pl)
Auto-transplantation of splenic tissue2
- C. R. Fleming, E. R. Dickson, E. G. Harrison, Jr: Splenosis: auto-transplantation of splenic tissue. (wikipedia.org)
- Splenosis is a rare condition defined as a heterotopic auto-transplantation of splenic tissue, typically after blunt abdominal trauma. (ac.ir)
Splenic tissue2
- Ectopic splenic tissue was first described in 1896 by Albrecht in Germany, whereas the term "splenosis" was first used by Buchbinder and Lipkoffin to describe their findings in 1939 A necessary requirement for splenosis is the rupture of the spleen, through a traumatic injury (such as a car wreck) or abdominal surgery, especially splenectomy. (wikipedia.org)
- Splenosis, the heterotopic autotransplantion of splenic tissue, is a common benign condition among patients with a history of splenic trauma. (utmb.edu)
Intrathoracic splenosis2
- Ashour M, Butchart EG, Breckenridge IM: Simultaneous intrathoracic and peritoneal splenosis with spontaneous regression of intrathoracic splenosis. (edu.pl)
- Arthinian, M.A. & Gillian, J.I. CT of Intrathoracic Splenosis in the Presence of Bronchogenic Carcinoma. (rayusradiology.com)
Splenectomy1
- Young JT et al: Splenosis: a remote consequence of traumatic splenectomy. (mhmedical.com)
Accessory spleen1
- We present an unique case with simultaneous occurrence of an accessory spleen and splenosis which were diagnosed following intentional radiological investigations conducted to evaluate flank pain which was probably related to the presence of the heterotopic spleens. (karger.com)
SPECT-CT1
- Hybrid Imaging with SPECT/CT and SPECT/MRI in Hepatic Splenosis. (snmjournals.org)
Renal2
- Dwyer NT, Whlan TF: Renal splenosis presenting as a renal mass. (edu.pl)
- CT complemented by isotopic liver-spleen scan is the radiological modality of choice in the diagnosis of renal fossa splenosis. (karger.com)
Abdominal5
- Splenosis in the abdominal category may occur in up to 65% of traumatic ruptures of the spleen. (wikipedia.org)
- Macroscopically, splenosis manifests as individual pieces of reddish-blue tissue with variable shape, which can be as few as one and as many as 300, mostly in the abdominal cavity, and varying in size from a few millimeters to as large as 12 cm. (wikipedia.org)
- Most cases of splenosis are intra-abdominal due to direct seeding of surrounding structures, although these ectopic rests may occur almost anywhere in the body, and its diffuse nature may raise the suspicion of metastatic cancer. (utmb.edu)
- A diagnosis of diffuse metastatic disease was initially considered before a diagnosis of intra-abdominal splenosis was ultimately made with the aid of Tc-99m sulfur colloid single-positron emission computed tomography (SPECT) and computed tomography imaging. (utmb.edu)
- We report a rare case of abdominal splenosis in a 7-year-old boy, 3 years after an abdominal blunt trauma. (ac.ir)
Colloid1
- Today colloid imaging remains useful for confirmation of splenosis and extramedullary hematopoiesis, but has otherwise been superseded by US, CT, and MRI for detection and evaluation of liver lesions. (radiologykey.com)
Diagnosis2
Asymptomatic2
- Treatment of splenosis is often unnecessary, because it is benign and usually asymptomatic. (wikipedia.org)
- Splenosis found in clinical practice is relatively rare because most patients are asymptomatic. (ac.ir)
Liver2
- Splenosis of the brain or liver is hypothesized to be the result of tiny pieces of spleen tissue traveling through the bloodstream. (wikipedia.org)
- In particular, splenosis is differentiated from different forms of lymphoma, metastisized cancers, cancer of the abdomen and pleural tissues, primary kidney or liver tumors, endometriosis or non-cancerous swollen lymph nodes. (wikipedia.org)
Case1
- Splenosis of the mesoappendix: case report and review of the literature. (edu.pl)
Presence1
- Splenosis must be distinguished from the presence of additional spleens, which are innate and are the result of differences in embryological development. (wikipedia.org)
Spleens1
- The whole process is called splenosis, and it seems to be pretty common: about 1 in 5 people have accessory spleens. (bloodraynebetrayal.com)
Injury1
- About a decade commonly passes between the injury and the discovery of splenosis. (wikipedia.org)
Condition2
- Splenosis: A Disease or a Beneficial Condition? (wikipedia.org)
- Occasionally, multiple spleen remnants can be found throughout the abdomen, often embedded in the neighboring pancreas, a condition called splenosis. (msdmanuals.com)
Common1
- Splenosis is slightly more common in males than females, probably due to the greater frequency of physical trauma experienced by men. (wikipedia.org)
Autotransplantation of splenic tissue2
- The case history is presented of a patient with breast cancer who was extensively investigated for presumed hepatic metastases, which were finally diagnosed as splenosis, the heterotopic autotransplantation of splenic tissue after traumatic rupture of the spleen. (nih.gov)
- Thoracic splenosis is a rare, benign condition involving autotransplantation of splenic tissue into the pleural cavity via trauma or surgery. (biomedcentral.com)
Rupture of the spleen1
- It is splenosis due to rupture of the spleen 10 years before. (ultrasoundmedicvn.com)
Intrahepatic3
- Splenosis usually occurs within the abdominal and pelvic cavities, but patients have been described with intrathoracic, subcutaneous, intrahepatic and intracranial lesions. (medscape.com)
- 9. Intrahepatic splenosis mimicking liver cancer: report of a case and review of literature. (nih.gov)
- Post-traumatic intrahepatic splenosis mimicking a neuroendocrine tumour. (nih.gov)
Intrathoracic3
- He was found to have a large intrathoracic splenosis. (biomedcentral.com)
- We herein describe a case of symptomatic intrathoracic splenosis in a 50-year-old man. (biomedcentral.com)
- 14. Intrathoracic splenosis - lesson learned: a case report. (nih.gov)
Symptomatic2
- Tissue infarction due to limited blood supply can be a cause of symptomatic splenosis. (wikipedia.org)
- Splenosis is usually found incidentally and unless symptomatic, therapy is not indicated. (medscape.com)
Splenic rupture1
- Splenosis is a common benign condition that occurs after splenic rupture via trauma or surgery. (medscape.com)
Tissue7
- Splenosis is the result of spleen tissue breaking off the main organ and implanting at another site inside the body. (wikipedia.org)
- Splenosis of the brain or liver is hypothesized to be the result of tiny pieces of spleen tissue traveling through the bloodstream. (wikipedia.org)
- Macroscopically, splenosis manifests as individual pieces of reddish-blue tissue with variable shape, which can be as few as one and as many as 300, mostly in the abdominal cavity, and varying in size from a few millimeters to as large as 12 cm. (wikipedia.org)
- C. R. Fleming, E. R. Dickson, E. G. Harrison, Jr: Splenosis: auto-transplantation of splenic tissue. (wikipedia.org)
- However, the lesion was determined to represent intrarenal splenosis, confirmed by Technetium-99m (99mTc) sulfur colloid scan and percutaneous biopsy, which revealed splenic tissue. (wustl.edu)
- After reoperation in December 2012 histology did not reveal any sign of neuroendocrine tumor but identified spleen tissue most probably caused by splenosis accidentally seeded at the first operation. (nel.edu)
- The uptake of Ga 68 dotatate can be seen in a variety of tumor types other than NETs (e.g., those derived from neural crest tissue), in sites of splenosis or other pathologic conditions, and as a normal physiologic variant (e.g., uncinate process of the pancreas). (nih.gov)
Peritoneal2
- 6. Intraperitoneal splenosis mimics peritoneal carcinomatosis of leiomyosarcoma and ovarian cancer. (nih.gov)
- Peritoneal splenosis mimicking peritoneal metastases from invasive ductal carcinoma of the breast (IDC). (eurorad.org)
Neuroendocrine1
- 10. Pancreatic splenosis mimicking neuroendocrine tumors: microhistological diagnosis by endoscopic ultrasound guided fine needle aspiration. (nih.gov)
Benign1
- Treatment of splenosis is often unnecessary, because it is benign and usually asymptomatic. (wikipedia.org)
Hepatic1
- 4. [Hepatic splenosis diagnosed by fine-needle cytology]. (nih.gov)
Uptake1
- Physiologically the spleen is highly avid at 68Ga-DOTATOC PET, but splenosis presents with less standard uptake value. (nel.edu)
Lymphoma2
- In particular, splenosis is differentiated from different forms of lymphoma, metastisized cancers, cancer of the abdomen and pleural tissues, primary kidney or liver tumors, endometriosis or non-cancerous swollen lymph nodes. (wikipedia.org)
- 15. Splenosis mimicking lymphoma. (nih.gov)
Ultrasound1
- For this case ULTRASOUND, CT, MRI CANNOT DIAGNOSE SPLENOSIS. (ultrasoundmedicvn.com)
Fremont1
- R. D. Fremont, T. W. Rice: Splenosis: A Review. (wikipedia.org)
Traumatic1
- Splenosis in the abdominal category may occur in up to 65% of traumatic ruptures of the spleen. (wikipedia.org)
Mass2
Review1
- Cite this: Splenosis: A Review - Medscape - Jun 01, 2007. (medscape.com)
Symptoms1
- Most people with splenosis have no symptoms, so the splenosis is discovered by chance through screening or in the process of diagnosing another disease. (wikipedia.org)
Rare1
- Intrarenal splenosis is very rare and its management is not well established. (wustl.edu)
Treatment1
- 8. Laparoscopic treatment of splenosis: report of a case. (nih.gov)
History1
- Abdominal splenosis: the importance of the medical history. (nih.gov)
Normal1
- El diagnóstico se confirma por serología viral negativa y bazo normal en la inspección macroscópica e histopatológica. (bvsalud.org)