Neoplasms of the sublingual glands.
A salivary gland on each side of the mouth below the TONGUE.
Tumors or cancer of the SALIVARY GLANDS.
A form of retention cyst of the floor of the mouth, usually due to obstruction of the ducts of the submaxillary or sublingual glands, presenting a slowly enlarging painless deep burrowing mucocele of one side of the mouth. It is also called sublingual cyst and sublingual ptyalocele.
Sebaceous gland neoplasms are uncommon cutaneous tumors that originate from the sebaceous glands, which can be benign (e.g., seborrheic keratosis, syringoma, trichofolliculoma) or malignant (e.g., sebaceous carcinoma, sebaceomatosis, mucoepidermoid carcinoma).
Tumors or cancer of the anal gland.
One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)
Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).
Perianal glands, also known as hepatoid glands, are sebaceous glands located in the perianal region of many mammals, including humans, that produce and secret lubricating oils for skin protection and cleanliness.
A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)
Tumors or cancer of the PAROTID GLAND.
The largest of the three pairs of SALIVARY GLANDS. They lie on the sides of the FACE immediately below and in front of the EAR.
A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)
Proteins and peptides found in SALIVA and the SALIVARY GLANDS. Some salivary proteins such as ALPHA-AMYLASES are enzymes, but their composition varies in different individuals.
A thin lining of closed cavities of the body, consisting of a single layer of squamous epithelial cells (MESOTHELIUM) resting on a thin layer of CONNECTIVE TISSUE, and covered with secreted clear fluid from blood and lymph vessels. Major serous membranes in the body include PERICARDIUM; PERITONEUM; and PLEURA.
Compounds of silver and proteins used as topical anti-infective agents.
Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA.
Cells lining the saclike dilatations known as acini of various glands or the lungs.
Total lack of teeth through disease or extraction.
Toxic, possibly carcinogenic, monomer of neoprene, a synthetic rubber; causes damage to skin, lungs, CNS, kidneys, liver, blood cells and fetuses. Synonym: 2-chlorobutadiene.
Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)
The "mouth floor" refers to the inferior aspect of the oral cavity, which is formed by the muscular floor of the mouth, consisting primarily of the mylohyoid muscle, and contains the opening of the sublingual and submandibular glands.
A gel-forming mucin that is predominantly expressed by submucosal glands of airway tissues and the SUBLINGUAL GLAND. It is one of the principal components of high molecular weight salivary mucin.
A usually benign tumor made up predominantly of myoepithelial cells.
A benign tumor characterized histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid.
Submandibular Gland Neoplasms are abnormal growths or tumors, which can be benign or malignant, originating from the glandular tissues of the submandibular salivary gland located beneath the mandible (jawbone).
Accessory salivary glands located in the lip, cheek, tongue, floor of mouth, palate and intramaxillary.

Acinic cell carcinoma found by recurrence of a mucous cyst in the sublingual gland. (1/7)

This case report describes an acinic cell carcinoma found by a recurrence of a ranula in the sublingual gland. A 42-year-old male was admitted to the hospital of the Tokyo Dental College with a swelling in his right oral floor but without pain. The lesion was treated by windowing the same day under the diagnosis of a ranula, but the swelling appeared again at the same area eight months after the first operation. A resection was performed, and the specimen was sent to the clinical laboratory for pathological diagnosis. Proliferating serous cells were seen in part of the wall of an exudative mucous cyst. PAS staining was partially positive, and immunohistochemical staining for S-100 protein, lactoferrin, and amylase were also positive in cytoplasmic granules. This report concludes that the pathological diagnosis is beneficial in clarifying the reasons for the recurrence of a benign lesion.  (+info)

Salivary glands: report of a rare case of myoepithelial carcinoma involving tongue base treated by CO2 Laser. (2/7)

Epithelial-myoepithelial carcinoma is a rare malignant tumour of the salivary glands. Herewith, the clinical evolution, anatomo-pathological characteristics and treatment adopted are described in a case occurring in the minor salivary glands of the tongue base. To our knowledge, this location has not been previously described in the literature. In fact, due to the rarity of the epithelial-myoepithelial carcinoma, there is no uniformity of data in the literature and very different therapeutic strategies have been suggested. In this report, the possibility of applying conservative surgery using CO(2) Laser is proposed. Results obtained in the case described confirm that conservative surgery is feasible in this type of neoplastic lesion of the tongue.  (+info)

Robotic-assisted transoral removal of a bilateral floor of mouth ranulas. (3/7)

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Carcinoma ex pleomorphic adenoma of the sublingual gland: a case report. (4/7)

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Mucoepidermoid carcinoma of sublingual gland: a malignant neoplasm in an uncommon region. (5/7)

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Bilateral submandibular gland lymphoma in Sjogren's syndrome. (6/7)

Salivary gland lymphoma is associated with Sjogren's syndrome. A case of bilateral submandibular gland and sublingual gland lymphoma, arising in Sjogren's syndrome, is presented. A lymphoma involving more than one salivary gland may occur in Sjogren's syndrome, and there is an increased risk of developing an extrasalivary lymphoma.  (+info)

Epstein-Barr virus (EBV) infection in salivary gland tumors: lytic EBV infection in nonmalignant epithelial cells surrounded by EBV-positive T-lymphoma cells. (7/7)

To elucidate the association of Epstein-Barr virus (EBV) and salivary gland tumors, 114 cases of tumors of major salivary glands were investigated. EBV DNA was detected in all 6 cases of undifferentiated carcinoma and all 3 cases of T-cell lymphoma, but not in other tumor tissues. In situ hybridization studies for EBV DNA and EBV-encoded small RNA 1 (EBER1) showed specific localization of the EBV sequences to the undifferentiated carcinoma cells and T-lymphoma cells. Moreover, intense DNA signals were detected on nonneoplastic epithelial cells of T-lymphoma tissues. These epithelial cells were negative for EBER1 and expressed BZLF1, BALF2, and gp350/220 proteins associated with virus production. In contrast, nonmalignant epithelial cells surrounded by undifferentiated carcinoma cells showed no evidence of EBV infection or virus replication. These results indicate that there is an unusual association of salivary gland T-cell lymphomas with lytic EBV replication of nonmalignant epithelial cells.  (+info)

Sublingual gland neoplasms refer to the abnormal growths or tumors that develop in the sublingual salivary glands, which are located beneath the tongue in the floor of the mouth. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign sublingual gland neoplasms are typically slow-growing and cause little to no discomfort, although they may become large enough to interfere with speaking, swallowing, or breathing. Malignant sublingual gland neoplasms, on the other hand, can grow rapidly, invade surrounding tissues, and potentially spread (metastasize) to other parts of the body.

The most common type of benign sublingual gland neoplasm is a pleomorphic adenoma, while malignant tumors may include mucoepidermoid carcinoma, adenoid cystic carcinoma, or squamous cell carcinoma. Treatment options for sublingual gland neoplasms depend on the type, size, location, and stage of the tumor but often involve surgical excision, with or without radiation therapy or chemotherapy. Regular follow-up care is essential to monitor for recurrence or metastasis.

The sublingual glands are a pair of salivary glands located in the floor of the mouth, beneath the tongue. They are the smallest of the major salivary glands and produce around 5-10% of the total saliva in the mouth. The sublingual glands secrete saliva containing electrolytes, enzymes (such as amylase), and antibacterial compounds that help in digestion, lubrication, and protection against microorganisms.

The sublingual glands' secretions are released through multiple small ducts called the ducts of Rivinus or minor sublingual ducts, as well as a larger duct called the duct of Wharton, which is a common excretory duct for both sublingual and submandibular glands.

Sublingual gland dysfunction can lead to conditions such as dry mouth (xerostomia), dental caries, or oral infections.

Salivary gland neoplasms refer to abnormal growths or tumors that develop in the salivary glands. These glands are responsible for producing saliva, which helps in digestion, lubrication of food and maintaining oral health. Salivary gland neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign neoplasms are slow-growing and typically do not spread to other parts of the body. They may cause symptoms such as swelling, painless lumps, or difficulty swallowing if they grow large enough to put pressure on surrounding tissues.

Malignant neoplasms, on the other hand, can be aggressive and have the potential to invade nearby structures and metastasize (spread) to distant organs. Symptoms of malignant salivary gland neoplasms may include rapid growth, pain, numbness, or paralysis of facial nerves.

Salivary gland neoplasms can occur in any of the major salivary glands (parotid, submandibular, and sublingual glands) or in the minor salivary glands located throughout the mouth and throat. The exact cause of these neoplasms is not fully understood, but risk factors may include exposure to radiation, certain viral infections, and genetic predisposition.

A ranula is a type of mucocele, which is a mucus-containing cyst that forms in the mouth. Specifically, a ranula is a mucocele that develops in the floor of the mouth, usually as a result of a blocked salivary gland duct. It appears as a smooth, dome-shaped swelling that is bluish or transparent in color. Ranulas can cause discomfort, particularly when speaking, eating, or swallowing, and they may interfere with normal oral function if they become large enough. Treatment typically involves surgical removal of the cyst, along with any affected salivary gland tissue.

Sebaceous gland neoplasms are abnormal growths or tumors that develop in the sebaceous glands, which are small oil-producing glands found in the skin. These glands are responsible for producing sebum, a natural oil that helps keep the skin and hair moisturized. Sebaceous gland neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign sebaceous gland neoplasms include:

* Seborrheic keratosis: These are common, harmless growths that appear as rough, scaly patches on the skin. They can be tan, brown, or black in color and vary in size from small to large.
* Sebaceous adenoma: This is a benign tumor that arises from the sebaceous glands. It typically appears as a small, yellowish bump on the skin.

Malignant sebaceous gland neoplasms include:

* Sebaceous carcinoma: This is a rare but aggressive form of skin cancer that arises from the sebaceous glands. It often appears as a hard, painless nodule on the eyelid or other areas of the face and can spread to other parts of the body if left untreated.
* Basal cell carcinoma: While not exclusively a sebaceous gland neoplasm, basal cell carcinomas can sometimes arise from the sebaceous glands. These are slow-growing but invasive skin cancers that typically appear as pearly or flesh-colored bumps on the skin.

It is important to have any new or changing growths on the skin evaluated by a healthcare professional to determine whether they are benign or malignant and to develop an appropriate treatment plan if necessary.

Anal gland neoplasms, also known as anal sac tumors, are abnormal growths that develop from the cells lining the anal glands. These glands are located on either side of the anus in dogs and some other animals, and they produce a scent used for marking territory.

Anal gland neoplasms can be benign or malignant (cancerous). Malignant tumors are more common and tend to grow quickly, invading surrounding tissues and spreading to other parts of the body (metastasis). Common symptoms of anal gland neoplasms include straining to defecate, bleeding from the rectum, and a firm mass that can be felt near the anus.

Treatment for anal gland neoplasms typically involves surgical removal of the tumor. In some cases, radiation therapy or chemotherapy may also be recommended. The prognosis for animals with anal gland neoplasms depends on several factors, including the size and location of the tumor, whether it has spread to other parts of the body, and the overall health of the animal.

The submandibular glands are one of the major salivary glands in the human body. They are located beneath the mandible (jawbone) and produce saliva that helps in digestion, lubrication, and protection of the oral cavity. The saliva produced by the submandibular glands contains enzymes like amylase and mucin, which aid in the digestion of carbohydrates and provide moisture to the mouth and throat. Any medical condition or disease that affects the submandibular gland may impact its function and could lead to problems such as dry mouth (xerostomia), swelling, pain, or infection.

Salivary glands are exocrine glands that produce saliva, which is secreted into the oral cavity to keep the mouth and throat moist, aid in digestion by initiating food breakdown, and help maintain dental health. There are three major pairs of salivary glands: the parotid glands located in the cheeks, the submandibular glands found beneath the jaw, and the sublingual glands situated under the tongue. Additionally, there are numerous minor salivary glands distributed throughout the oral cavity lining. These glands release their secretions through a system of ducts into the mouth.

Perianal glands, also known as hepatoid glands or circumanal glands, are specialized sebaceous glands located in the perianal region of many mammals, including dogs and cats. These glands are found in the skin around the anus and are responsible for producing a scent that is unique to each individual animal. The secretions from these glands play a role in territorial marking and communication.

In humans, there are no true perianal glands, but there are some sweat glands located in the perianal region that can sometimes become inflamed or infected, leading to conditions such as hidradenitis suppurativa or perianal abscesses. However, these conditions are not related to the perianal glands found in animals.

A pleomorphic adenoma is a type of benign (non-cancerous) tumor that typically develops in the salivary glands, although they can also occur in other areas such as the nasopharynx and skin. "Pleomorphic" refers to the diverse appearance of the cells within the tumor, which can vary in size, shape, and arrangement.

Pleomorphic adenomas are composed of a mixture of epithelial and mesenchymal cells, which can form glandular structures, squamous (scale-like) cells, and areas that resemble cartilage or bone. These tumors tend to grow slowly and usually do not spread to other parts of the body.

While pleomorphic adenomas are generally not dangerous, they can cause problems if they become large enough to press on surrounding tissues or structures. In some cases, these tumors may also undergo malignant transformation, leading to a cancerous growth known as carcinoma ex pleomorphic adenoma. Surgical removal is the standard treatment for pleomorphic adenomas, and the prognosis is generally good with proper management.

Parotid neoplasms refer to abnormal growths or tumors in the parotid gland, which is the largest of the salivary glands and is located in front of the ear and extends down the neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign parotid neoplasms are typically slow-growing, painless masses that may cause facial asymmetry or difficulty in chewing or swallowing if they become large enough to compress surrounding structures. The most common type of benign parotid tumor is a pleomorphic adenoma.

Malignant parotid neoplasms, on the other hand, are more aggressive and can invade nearby tissues and spread to other parts of the body. They may present as rapidly growing masses that are firm or fixed to surrounding structures. Common types of malignant parotid tumors include mucoepidermoid carcinoma, adenoid cystic carcinoma, and squamous cell carcinoma.

The diagnosis of parotid neoplasms typically involves a thorough clinical evaluation, imaging studies such as CT or MRI scans, and fine-needle aspiration biopsy (FNAB) to determine the nature of the tumor. Treatment options depend on the type, size, and location of the neoplasm but may include surgical excision, radiation therapy, and chemotherapy.

The parotid gland is the largest of the major salivary glands. It is a bilobed, accessory digestive organ that secretes serous saliva into the mouth via the parotid duct (Stensen's duct), located near the upper second molar tooth. The parotid gland is primarily responsible for moistening and lubricating food to aid in swallowing and digestion.

Anatomically, the parotid gland is located in the preauricular region, extending from the zygomatic arch superiorly to the angle of the mandible inferiorly, and from the masseter muscle anteriorly to the sternocleidomastoid muscle posteriorly. It is enclosed within a fascial capsule and has a rich blood supply from the external carotid artery and a complex innervation pattern involving both parasympathetic and sympathetic fibers.

Parotid gland disorders can include salivary gland stones (sialolithiasis), infections, inflammatory conditions, benign or malignant tumors, and autoimmune diseases such as Sjögren's syndrome.

Mucoepidermoid carcinoma is a type of cancer that develops in the salivary glands or, less commonly, in other areas such as the lungs or skin. It is called "mucoepidermoid" because it contains two types of cells: mucus-secreting cells and squamous (or epidermoid) cells.

Mucoepidermoid carcinomas can vary in their behavior, ranging from low-grade tumors that grow slowly and rarely spread to other parts of the body, to high-grade tumors that are aggressive and can metastasize. The treatment and prognosis for mucoepidermoid carcinoma depend on several factors, including the grade and stage of the tumor, as well as the patient's overall health.

It is important to note that while I strive to provide accurate and up-to-date information, this definition may not capture all the nuances of this medical condition. Therefore, it is always best to consult with a healthcare professional for medical advice.

Salivary proteins and peptides refer to the diverse group of molecules that are present in saliva, which is the clear, slightly alkaline fluid produced by the salivary glands in the mouth. These proteins and peptides play a crucial role in maintaining oral health and contributing to various physiological functions.

Some common types of salivary proteins and peptides include:

1. **Mucins**: These are large, heavily glycosylated proteins that give saliva its viscous quality. They help to lubricate the oral cavity, protect the mucosal surfaces, and aid in food bolus formation.
2. **Amylases**: These enzymes break down carbohydrates into simpler sugars, initiating the digestive process even before food reaches the stomach.
3. **Proline-rich proteins (PRPs)**: PRPs contribute to the buffering capacity of saliva and help protect against tooth erosion by forming a protective layer on tooth enamel.
4. **Histatins**: These are small cationic peptides with antimicrobial properties, playing a significant role in maintaining oral microbial homeostasis and preventing dental caries.
5. **Lactoferrin**: An iron-binding protein that exhibits antibacterial, antifungal, and anti-inflammatory activities, contributing to the overall oral health.
6. **Statherin and Cystatins**: These proteins regulate calcium phosphate precipitation, preventing dental calculus formation and maintaining tooth mineral homeostasis.

Salivary proteins and peptides have attracted significant interest in recent years due to their potential diagnostic and therapeutic applications. Alterations in the composition of these molecules can provide valuable insights into various oral and systemic diseases, making them promising biomarkers for disease detection and monitoring.

A serous membrane is a type of thin, smooth tissue that lines the inside of body cavities and surrounds certain organs. It consists of two layers: an outer parietal layer that lines the cavity wall, and an inner visceral layer that covers the organ. Between these two layers is a small amount of fluid called serous fluid, which reduces friction and allows for easy movement of the organs within the body cavity.

Serous membranes are found in several areas of the body, including the pleural cavity (around the lungs), the pericardial cavity (around the heart), and the peritoneal cavity (around the abdominal organs). They play an important role in protecting these organs and allowing them to move smoothly within their respective cavities.

Silver proteins are a type of compound that consists of silver ions (Ag+) bonded to protein molecules. These compounds are often used in medical applications, including topical creams and ointments, for their antimicrobial properties. The silver ions in the compound can help to kill or inhibit the growth of a wide range of microorganisms, including bacteria, fungi, and viruses.

The protein component of silver proteins helps to stabilize the silver ions and control their release, which can improve the efficacy and safety of the product. The protein may also help to enhance the penetration of the silver ions into the skin or other tissues, allowing for more effective killing of microorganisms.

Silver proteins are used in a variety of medical products, including wound dressings, creams and gels for the treatment of burns and other types of wounds, and as a coating on medical devices to prevent infection. They have been shown to be effective against a wide range of microorganisms, including antibiotic-resistant strains, making them a valuable tool in the fight against infectious diseases.

Palatal neoplasms refer to abnormal growths or tumors that occur on the palate, which is the roof of the mouth. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slower growing and less likely to spread, while malignant neoplasms are more aggressive and can invade nearby tissues and organs.

Palatal neoplasms can have various causes, including genetic factors, environmental exposures, and viral infections. They may present with symptoms such as mouth pain, difficulty swallowing, swelling or lumps in the mouth, bleeding, or numbness in the mouth or face.

The diagnosis of palatal neoplasms typically involves a thorough clinical examination, imaging studies, and sometimes biopsy to determine the type and extent of the growth. Treatment options depend on the type, size, location, and stage of the neoplasm but may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up care is essential to monitor for recurrence or spread of the neoplasm.

Acinar cells are the type of exocrine gland cells that produce and release enzymes or other secretory products into a lumen or duct. These cells are most commonly found in the acini (plural of acinus) of the pancreas, where they produce digestive enzymes that are released into the small intestine to help break down food.

The acinar cells in the pancreas are arranged in clusters called acini, which are surrounded by a network of ducts that transport the secreted enzymes to the duodenum. Each acinus contains a central lumen, into which the digestive enzymes are released by the acinar cells.

Acinar cells have a distinctive morphology, with a large, centrally located nucleus and abundant cytoplasm that contains numerous secretory granules. These granules contain the enzymes that are synthesized and stored within the acinar cells until they are released in response to hormonal or neural signals.

In addition to their role in digestion, acinar cells can also be found in other exocrine glands, such as the salivary glands, where they produce and release enzymes that help to break down food in the mouth.

"Edentulous mouth" is a medical term used to describe a condition where an individual has no remaining natural teeth in either their upper or lower jaw, or both. This situation can occur due to various reasons such as tooth decay, gum disease, trauma, or aging. Dentists often recommend dental prosthetics like dentures to restore oral function and aesthetics for individuals with edentulous mouths.

Chloroprene is a colorless liquid with a mild, rubbery odor. It is chemically known as 2-chlorobuta-1,3-diene and is primarily used in the industrial production of polychloroprene, a type of synthetic rubber that is resistant to heat, oil, and weathering.

In a medical context, chloroprene itself is not commonly used or encountered. However, exposure to chloroprene during its manufacture or use in industrial settings has been associated with an increased risk of certain health effects, including neurological damage, liver toxicity, and cancer. Therefore, occupational safety regulations exist to limit worker exposure to this chemical.

Adenoid cystic carcinoma (AdCC) is a rare type of cancer that can occur in various glands and tissues of the body, most commonly in the salivary glands. AdCC is characterized by its slow growth and tendency to spread along nerves. It typically forms solid, cystic, or mixed tumors with distinct histological features, including epithelial cells arranged in tubular, cribriform, or solid patterns.

The term "carcinoma" refers to a malignant tumor originating from the epithelial cells lining various organs and glands. In this case, adenoid cystic carcinoma is a specific type of carcinoma that arises in the salivary glands or other glandular tissues.

The primary treatment options for AdCC include surgical resection, radiation therapy, and sometimes chemotherapy. Despite its slow growth, adenoid cystic carcinoma has a propensity to recur locally and metastasize to distant sites such as the lungs, bones, and liver. Long-term follow-up is essential due to the risk of late recurrences.

The term "mouth floor" is not a standard medical terminology. However, it might refer to the floor of the mouth, which is the part of the oral cavity located beneath the tongue and above the hyoid bone, which is a U-shaped bone in the front of the neck that helps support the tongue. The mouth floor contains several salivary glands, muscles, and nerves that are important for functions such as swallowing and speaking.

Mucin-5B, also known as MUC5B, is a type of mucin protein that is heavily glycosylated and found in the respiratory tract. It is one of the major components of airway mucus, which helps to trap and remove inhaled particles and microorganisms from the lungs.

Mucin-5B is a large molecular weight gel-forming mucin that is produced by goblet cells and submucosal glands in the respiratory epithelium. It has a complex structure, consisting of a protein backbone with numerous oligosaccharide side chains that give it its gel-like properties.

Mutations in the MUC5B gene have been associated with several lung diseases, including chronic obstructive pulmonary disease (COPD), bronchiectasis, and idiopathic pulmonary fibrosis (IPF). In particular, a common genetic variant in the MUC5B promoter region has been identified as a significant risk factor for developing IPF.

Myoepithelioma is a very rare, benign (non-cancerous) tumor that arises from the myoepithelial cells, which are found in various glands throughout the body, including salivary glands, sweat glands, and mammary glands. These tumors typically appear as slow-growing, painless masses. While they are usually benign, some myoepitheliomas can become malignant (cancerous) and invasive, leading to more serious health concerns. Treatment for myoepithelioma typically involves surgical removal of the tumor.

Adenolymphoma is a rare, benign tumor that arises from the lymphoid tissue found in glandular structures, such as the salivary glands. It is also known as Warthin's tumor or cystic papillary adenolymphoma.

The tumor is composed of multiple cyst-like spaces lined by columnar epithelial cells and surrounded by lymphoid tissue, which may contain lymphocytes, plasma cells, and occasionally, germinal centers. The etiology of adenolymphoma is unclear, but it has been associated with smoking and genetic factors.

Adenolymphomas are typically slow-growing and painless, although they can cause discomfort or facial asymmetry if they become large enough. They are usually diagnosed through imaging studies such as ultrasound, CT scan, or MRI, followed by a biopsy to confirm the diagnosis.

Treatment of adenolymphoma typically involves surgical excision, which is usually curative. Recurrence after surgery is rare, but long-term follow-up is recommended due to the potential for malignant transformation into squamous cell carcinoma or other malignancies.

Submandibular gland neoplasms refer to abnormal growths or tumors that develop in the submandibular glands. These are one of the three pairs of major salivary glands located beneath the jaw and produce saliva that helps in digestion. Submandibular gland neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign neoplasms are typically slow-growing, do not invade surrounding tissues, and rarely spread to other parts of the body. Common types of benign submandibular gland neoplasms include pleomorphic adenomas and monomorphic adenomas.

Malignant neoplasms, on the other hand, are aggressive and can invade nearby structures or metastasize (spread) to distant organs. Common types of malignant submandibular gland neoplasms include mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma.

Symptoms of submandibular gland neoplasms may include a painless swelling or mass in the neck, difficulty swallowing, speaking, or breathing, numbness or tingling in the tongue or lips, and unexplained weight loss. Treatment options depend on the type, size, location, and stage of the tumor but often involve surgical excision, radiation therapy, and/or chemotherapy. Regular follow-up care is essential to monitor for recurrence or metastasis.

Minor salivary glands are numerous small exocrine glands that produce saliva and are distributed throughout the oral cavity, nasal cavity, pharynx, larynx, and paranasal sinuses. They are classified as "minor" due to their smaller size compared to the three pairs of major salivary glands (parotid, submandibular, and sublingual). The minor salivary glands are primarily mucous glands, although some contain serous cells. They are responsible for producing approximately 5-10% of the total saliva in the mouth. These glands help moisten the oral cavity, protect the mucosal lining, and facilitate speaking, chewing, and swallowing.

Pathology arising from the sublingual gland is rare, however, sublingual gland neoplasms are predominantly malignant and thus ... the sublingual salivary gland. Saliva from the sublingual gland drains through several small excretory ducts in the floor of ... sublingual and submental spaces are sometimes termed the perimandibular spaces, or the submaxillary space. "Sublingual space". ... the intrinsic muscles of the tongue and genioglossus separate the two halves of the sublingual space. The sublingual space ...
... parotid glands, submandibular glands and sublingual glands) of the head and neck. Carcinoma is a term for malignant neoplasms ... Salivary gland-like carcinomas of the lung generally refers a class of rare cancers that arise from the uncontrolled cell ... Icotinib has been temporarily effective at treating salivary gland-like carcinoma of the lung but loses efficiency after three ... and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A ...
The major salivary glands consist of the parotid, submandibular, and sublingual glands. The minor salivary glands consist of ... also known as mucous gland adenomas or neoplasms, are tumours that form in the tissues of salivary glands. The salivary glands ... Around 50% of the tumours found in the submandibular glands are benign. Sublingual gland tumours are very rare but if present, ... Salivary gland tumours usually present as a lump or swelling in the affected gland which may or may not have been present for a ...
Humans have three major salivary glands: parotid, submandibular, and sublingual. These glands, along with additional minor ... and neoplasms. The following conditions are among those that can be detected through saliva testing (list not comprehensive): ... Nitrate extracted from blood by the salivary gland, accumulates in saliva, which is then reduced to nitric oxide to have a ... Most of these substances enter the salivary gland acinus and duct system from the surrounding capillaries via the intervening ...
There are three paired major salivary glands in humans: the parotid glands, the submandibular glands, and the sublingual glands ... Frey's syndrome Salivary gland neoplasm Relative incidence of parotid tumors. Relative incidence of submandibular tumors. A ... they are usually associated with the sublingual gland, and less often they arise from the submandibular gland or a minor ... The sublingual gland is below the tongue, on the floor of the mouth; it drains its mostly mucous saliva into the mouth via ...
... they are submandibular and sublingual glands. Sometimes accessory parotid glands are found close to the main parotid glands. ... Pleomorphic adenoma is seen to be a common benign neoplasm of the salivary gland and has an overall incidence of 54-68%. The ... A normal parotid gland is barely palpable and a normal sublingual gland is not palpable. Intra-oral examination should include ... The parotid gland is a major salivary gland in many animals. In humans, the two parotid glands are present on either side of ...
Neoplasms, such as metastatic squamous cell carcinoma to the submandibular lymph nodes or a salivary gland tumour, could create ... The anterior defects may be associated with the sublingual salivary gland. Stafne's defect is usually discovered by chance ... Very rarely, since the defect contains salivary gland tissue, salivary gland tumors can occur within an established defect but ... as the depression is created by ectopic salivary gland tissue associated with the submandibular gland and does not represent a ...
... salivary gland neoplasms MeSH C07.465.565.824.695 - parotid neoplasms MeSH C07.465.565.824.882 - sublingual gland neoplasms ... salivary gland neoplasms MeSH C07.465.815.718.589 - parotid neoplasms MeSH C07.465.815.718.870 - sublingual gland neoplasms ... submandibular gland neoplasms MeSH C07.465.565.925 - tongue neoplasms MeSH C07.465.614.187 - dental fistula MeSH C07.465. ... submandibular gland diseases MeSH C07.465.815.882.500 - submandibular gland neoplasms MeSH C07.465.815.929 - xerostomia MeSH ...
The parotid and sublingual glands account for the remaining. The gland receives its blood supply from the facial and lingual ... Steve C Lee, MD, PhD (22 December 2022). "Salivary Gland Neoplasms". Medscape.{{cite journal}}: CS1 maint: multiple names: ... Submandibular gland inflammation as seen on ultrasound Submandibular gland Submandibular gland Submandibular gland lateral view ... The two other types of salivary glands are parotid and sublingual glands. Mandible. Inner surface. Side view. Distribution of ...
There have been rare cases of primary tumors involving the parapharyngeal space and the sublingual gland. Micrograph of acinic ... Lee SC (22 December 2022). "Salivary Gland Neoplasms". Medscape. Updated: Jan 13, 2021 Diagrams by Mikael Häggström, MD ... 52 years) than most other salivary gland cancers. Occurrences in children are quite common. Salivary gland cancers seem on the ... Other sites of primary tumors have included the submandibular gland and other major and minor salivary glands. ...
... salivary gland neoplasms MeSH C04.588.443.591.824.695 - parotid neoplasms MeSH C04.588.443.591.824.882 - sublingual gland ... sebaceous gland neoplasms MeSH C04.588.805.776 - sweat gland neoplasms MeSH C04.588.839.500 - muscle neoplasms MeSH C04.588. ... anal gland neoplasms MeSH C04.588.274.476.411.445 - duodenal neoplasms MeSH C04.588.274.476.411.501 - ileal neoplasms MeSH ... peritoneal neoplasms MeSH C04.588.322.078 - adrenal gland neoplasms MeSH C04.588.322.078.265 - adrenal cortex neoplasms MeSH ...
Saliva is secreted from 3 pairs of major salivary glands (parotid, submandibular, sublingual) alongside many minor salivary ... Benign soft tissue neoplasms 1. Peripheral nerve sheath tumours most commonly are traumatic neuromas, a reactive response to ... However, they are not true benign neoplasms (denoted by suffix ~oma), which are similar in appearance but very rare in the ... If present, the submucosa usually contains loose connective tissue and may also contain adipose tissue or salivary glands, as ...
... the most common being the parotid gland, followed by submandibular and sublingual glands. It should not be confused with ... Typically presents unilaterally in submandibular gland that cannot be differentiated clinically from a neoplasm, with pain an ... Parotid gland recurrent painful swellings Submandibular gland usually secondary to sialolithiasis or stricture Sialadenitis is ... It is characterised by bilateral swelling of the parotid glands, however other major salivary glands may also be affected in ...
benign): approximately 20% to 25% of parotid tumors, 35% to 40% of submandibular tumors, and more than 90% of sublingual gland ... indurated and enlarged masses that are clinically indistinguishable from salivary gland neoplasms or tumors. It is now regarded ... but is also known to occur in other major and minor salivary glands, including the parotid gland. Overall, salivary gland ... Chan ACL; Chan JKC; Abbondanzo SL (2005). "Chapter 5. Tumours of the Salivary Glands" (PDF). In Leon Barnes; John W. Eveson; ...
In accordance, androstanolone has been found to not increase prostate gland size in men. Conversely, due to lack of ... Dao TL (1975). "Pharmacology and Clinical Utility of Hormones in Hormone Related Neoplasms". In Sartorelli AC, Johns DJ (eds ... The available formulations of androstanolone include buccal or sublingual tablets (Anabolex, Stanolone), topical gels ( ... and prostate gland, thereby improving its ratio of anabolic to androgenic effects. However, androstanolone is nonetheless ...
Humans have three paired major salivary glands (parotid, submandibular, and sublingual), a pair of seromucous tubarial glands ( ... Papillary - In oncology, papillary refers to neoplasms with projections ("papillae", from Latin, 'nipple') that have ... Adrenal gland - The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones ... Salivary gland - The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts. ...
Clayton RW, Göbel K, Niessen CM, Paus R, van Steensel MAM, Lim X (October 2019). "Homeostasis of the sebaceous gland and ... Estrogens can be administered via a variety of routes, including by mouth, sublingual, transdermal/topical (gel, patch), ... "Pharmacology and Clinical Utility of Hormones in Hormone Related Neoplasms". In Alan C. Sartorelli, David G. Johns (eds.). ... Pochi PE, Strauss JS (August 1973). "Sebaceous gland suppression with ethinyl estradiol and diethylstilbestrol". Arch Dermatol ...
Malignant neoplasm of parotid gland C08.0 Malignant neoplasm of submandibular gland C08.1 Malignant neoplasm of sublingual ... Malignant neoplasm of unspecified part of right adrenal gland C74.92 Malignant neoplasm of unspecified part of left adrenal ... Malignant neoplasm of scapula and long bones of right upper limb C40.02 Malignant neoplasm of scapula and long bones of left ... Other specified malignant neoplasm of skin of other parts of face C44.40 Unspecified malignant neoplasm of skin of scalp and ...
Categories: Sublingual Gland Neoplasms Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Pathology arising from the sublingual gland is rare, however, sublingual gland neoplasms are predominantly malignant and thus ... the sublingual salivary gland. Saliva from the sublingual gland drains through several small excretory ducts in the floor of ... sublingual and submental spaces are sometimes termed the perimandibular spaces, or the submaxillary space. "Sublingual space". ... the intrinsic muscles of the tongue and genioglossus separate the two halves of the sublingual space. The sublingual space ...
They may be broadly categorized into benign neoplasms, tumorlike conditions, and malignant neoplasms. ... Tumors of the salivary glands are uncommon and represent 2-4% of head and neck neoplasms. ... The sublingual gland is located between the mylohyoid and hyoglossus muscles. The gland is rather superficial and is covered by ... The salivary glands exist as larger named "major" glands and also as many widely dispersed "minor" glands that exist throughout ...
... followed by the submandibular gland (66 % vs. 34 %). No tumors were found in the sublingual glands. Benign neoplasms accounted ... OBJECTIVES: To characterize the presentation and treatment of children presenting with primary salivary gland neoplasms. ... between 2000 and 2020 that analysed the effect of radiotherapy on salivary gland neoplasms and ACCs of salivary glands and met ... BACKGROUND: Acinic cell carcinomas (AciCCs) are malignant tumours of the salivary glands. The aim of this work was to analyse ...
... glands (9.24%) and just one case of sublingual gland tumour (0.86%) . Pleomorphic adenoma forming 59.7% of the total salivary ... Salivary gland neoplasms: a study of 119 cases Patologia. Santos, Gilda da Cunha; Martins, Marcos Roberto; Pellacani, Lucila ... Mucous gland adenoma is a rare benign tumor arising from the mucous secreting glands of the larger airway mucosa. The majority ... METHODS: We retrospectively evaluated 205.967 pathological reports and we found 119 salivary gland tumours, 93 benign neoplasms ...
They can be present in different locations and have different histologies, including the sublingual, parotid, minor salivary ... Salivary gland neoplasms are abnormal cells growing in the salivary gland or in the ducts that drain the glands. They can be ... Salivary gland neoplasms are abnormal cells growing in the salivary gland or in the ducts that drain the glands. They can be ... Salivary gland neoplasms are abnormal cells growing in the salivary gland or in the ducts that drain the glands. ...
65.19% of salivary gland neoplasms in this study had parotid gland involvement and sublingual gland involvement had the lowest ... Major salivary glands include parotid, submandibular, and sublingual glands and minor ones include hundreds of small glands ... of salivary gland cancers were originated from sublingual gland. Most patients (52 or 33.1 %) had T3, then T4 (49 or 31%), T2 ( ... minor salivary glands (23%) and submandibular gland (15%) [5]. In minor salivary glands, palate was the most common site (68 ...
Major salivary glands Gland: parotid sublingual submandibular Excludes: benign neoplasms of minor salivary glands which are to ... 142.0 Parotid gland 142.1 Submandibular gland Submaxillary gland 142.2 Sublingual gland 142.8 Other [see Note 3 at beginning of ... Benign neoplasm of thyroid glands 227 Benign neoplasm of other endocrine glands and related structures 227.0 Suprarenal gland ... 235 Neoplasm of uncertain behavior of digestive and respiratory systems 235.0 Major salivary glands Gland: parotid sublingual ...
"Parotid Gland" "Submandibular Gland" "Sublingual Gland" Sialorrhea "Salivary Ducts" Parotidectomy Submandibulectomy "Accessory ... "Thyroid Gland nodule" thyroidectomy Parathyroidectomy "Parathyroid nodule" "Thyroid cancer" "Thyroid neoplasm". ORL P DIATRIQUE ... salivary gland" Salivation ((Lithiasis) AND Salivary parotid Submandibular Sublingual). GLANDES THYROIDE & PARATHYROIDES. " ... " "squamous cell neoplasm") AND palliation treatment staging diagnosis HPV "treatment outcomes" irradiation radiotherapy mouth ...
They can originate from trauma to or obstruction of the sublingual salivary gland. Less commonly, the submandibular gland or ... Lipomas represent about 1 to 5 percent of all neoplasms of the oral cavity.8 Superficial lipomas are slow-growing, soft, ... Localized collection of mucus underneath the tongue, usually arising from trauma to the sublingual salivary gland. ... Physical examination revealed a nontender, bluish, fluctuant sublingual mass with no obvious extension into the neck (see ...
... such as diagnosing problems involving the major and minor salivary glands, in the management of oral dryness associated with ... Dentists are involved with aspects of salivary gland function in several ways, ... Also see Salivary Gland Tumors, Major Benign; Salivary Gland Tumors, Minor Benign; and Salivary Gland Neoplasms. ... The sublingual glands, under the tongue, produce about 5% of the total oral saliva. Approximately 1000 minor glands, localized ...
Malignant neoplasm of parotid gland C08.0 Malignant neoplasm of submandibular gland C08.1 Malignant neoplasm of sublingual ... Malignant neoplasm of overlapping sites of unspecified parts of mouth C06.89 Malignant neoplasm of overlapping sites of other ... Personal history of malignant neoplasm of larynx Z85.818 Personal history of malignant neoplasm of other sites of lip, oral ... Personal history of malignant neoplasm of unspecified site of lip, oral cavity, and pharynx ...
Sublingual Gland 33% * fucoidan 33% * Chemokine CX3CL1 33% * recombinant human bone morphogenetic protein-2 33% ...
... expands on salivary gland cancer and why a skilled surgeon is imperative to avoid nerve damage. ... and the sublingual gland under the tongue.. The minor salivary glands and submandibular glands are largely responsible for the ... Unfortunately, we dont know the cause of salivary gland tumours. We almost always recommend excision of salivary neoplasms ... Salivary gland tumours. Eighty percent of salivary gland tumours occur in the parotid gland, 80% of these are non-cancerous and ...
These are less common than parotid gland tumors but can also be benign or malignant.. 3. Sublingual gland tumors: These are ... Liver Neoplasms Entry term(s). Hepatic Neoplasm Hepatic Neoplasms Liver Neoplasm Neoplasm, Hepatic Neoplasm, Liver Neoplasms ... Pancreatic DuctalNeoplasms, Vascular TissueEye NeoplasmsNose NeoplasmsNeoplasms, Radiation-InducedSalivary Gland Neoplasms ... Liver Neoplasm. Neoplasm, Hepatic. Neoplasm, Liver. Neoplasms, Hepatic. Neoplasms, Liver. ... Cancer of Liver Entry term(s). ...
... sublingual and minor salivary gland tumors.",. keywords = "Diagnostic accuracy, Malignancy, Salivary gland neoplasm", ... sublingual and minor salivary gland tumors.. AB - Obtaining reliable pre-operative diagnosis is crucial in planning treatment ... Lee, W. H., Tseng, T. M., Hsu, H. T., Lee, F. P., Hung, S. H., & Chen, P. Y. (2014). Salivary gland tumors: A 20-year review of ... Lee, WH, Tseng, TM, Hsu, HT, Lee, FP, Hung, SH & Chen, PY 2014, Salivary gland tumors: A 20-year review of clinical diagnostic ...
MR of the Submandibular Gland: Normal and Pathologic States Takashi Kaneda, Manabu Minami, Kaoru Ozawa, Yoshiaki Akimoto, ... Salivary Gland Diseases. Parotid gland Submandibular gland Sublingual gland Salivary Glands Overview.. ... Salivary Gland Neoplasms Outline€¦ · · 2018-04-16malignant neoplasm of the submandibular gland Adenoid Cystic Carcinoma ... in the submandibular gland, and the remaining 10% in the minor salivary gland and sublingual gland (2). The proportion of ...
... sublingual (2), and submandibular (1) glands. All presented as rapidly growing masses treated by surgery followed by adjuvant ... Histologic examination showed poorly differentiated neoplasms composed of poorly cohesive small-sized to medium-sized cells ... Review of the reported salivary gland NC cases (total, 10) showed a male:female ratio of 1.5:1 and an age range of 12 to 55 ... We herein describe 3 new cases (all affecting the parotid gland) in 2 women (39- and 55-y old) and 1 man (35-y old). ...
Most common salivary gland to be affected with sialolithiasis is (A) Parotid (B) Submandibular (C) Palatal (D) Sublingual. Ans ... Which of the following syndromes is characterized by facial trichilemmomas, gastrointestinal polyps, thyroid neoplasms, pebbly ... C) Film made at the time contrast agent has been emptied from the respective glands & ducts (D) Film which is taken 2 hours ... A) Synovial fluid (B) Saliva from parotid gland (C) Lacrimal fluid (D) Gingival crevicular fluid. Ans: B. 7. Free radicals are ...
Schwannoma arising from the sublingual glandular branch of the lingual nerve radiologically masquerading as sublingual gland ... report of a case with a review of the literature on aberrant salivary gland tissue and neoplasms," Oral Surgery, ... A Rare Primary Neuroendocrine Tumor (Typical Carcinoid) of the Sublingual Gland We here present an extremely rare case of a ... It was resected under local anesthesia and at excision it was completely detached from the sublingual salivary gland and ...
... such as diagnosing problems involving the major and minor salivary glands, in the management of oral dryness associated with ... Dentists are involved with aspects of salivary gland function in several ways, ... Also see Salivary Gland Tumors, Major Benign; Salivary Gland Tumors, Minor Benign; and Salivary Gland Neoplasms. ... The sublingual glands, under the tongue, produce about 5% of the total oral saliva. Approximately 1000 minor glands, localized ...
Salivary gland tumors are abnormal cells growing in the gland or in the tubes (ducts) that drain the salivary glands. ... Salivary gland tumors are abnormal cells growing in the gland or in the tubes (ducts) that drain the salivary glands. ... Two submandibular glands are under the floor of the mouth on both sides of the back of the jaw. Two sublingual glands are under ... Benign neoplasms of the salivary glands. In: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Head and ...
Rare: 2.3% of benign salivary tumors 6 th decade M:F = 1:1 Parotid: 78% Submandibular gland: 9% Minor salivary glands: palate, ... Salivary Gland Tumors. Marka Crittenden M.D. Ph.D. Anatomy. Major Glands Parotid, submandibular and sublingual glands Minor ... Salivary Gland Neoplasms. Salivary Gland Neoplasms. Benign NeoplasmsMalignant NeoplasmsControversial Issues. Salivary Gland ... Salivary Gland Diseases. Salivary Gland Diseases. The salivary glands consist of 3 paired major glands, 1- parotid glands: ...
... also known as mucous gland adenomas or neoplasms, are tumours that form in the tissues of salivary glands.The salivary glands ... are classified as major or minor.The major salivary glands consist of the parotid, submandibular, and sublingual glands. ... Anderson and search our database for open studies gland cancer is a rare. Be solid, round and hollow or they may have holes in ... Or prostate gland longer about anything other than surviving after the longest Disease-Free interval was observed the... Some ...
sublingual gland - K11.0 Atrophy of salivary gland. *submandibular gland - K11.0 Atrophy of salivary gland ... neoplastic disease - See Also: Neoplasm; - D49.9 Neoplasm of unspecified behavior of unspecified site ... lacrimal gland (primary) - H04.14 Primary lacrimal gland atrophy*secondary - H04.15 Secondary lacrimal gland atrophy ... thyroid (gland) (acquired) - E03.4 Atrophy of thyroid (acquired)*congenital (with myxedema) - E03.1 Congenital hypothyroidism ...
Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. ... Neoplasms, Cystic, Mucinous, and Serous [C04.557.470.590]. *Carcinoma, Mucoepidermoid [C04.557.470.590.340] ... Salivary gland-type tumors of the breast: a spectrum of benign and malignant tumors including "triple negative carcinomas" of ... Anatomic extent of lymph node metastases as an independent prognosticator in node-positive major salivary gland carcinoma: A ...
... sublingual glands, soft and hard palate, uvula, epiglottis).. *Terms indicating poisoning: antidote, emesis, gastric aspiration ... skin/soft tissues/organ/eye lesions (might be dermatological disorders, polyps, neoplasms, etc.) ... sublingual glands, soft and hard palate, uvula, epiglottis). ... lacrimal gland), nasal turbinate were excluded, as well as ... neoplasms, obstetrics, perioperative states, aneurysms, ulcers, inflammatory and infectious diseases, arthrodesis, conization, ...
  • The salivary glands are divided into 2 groups: the major salivary glands and the minor salivary glands. (medscape.com)
  • The major salivary glands consist of the following 3 pairs of glands: the parotid glands, the submandibular glands, and the sublingual glands. (medscape.com)
  • Major salivary gland surgery is essentially nerve surgery, meaning a critical aspect of the operation is identifying and preserving cranial nerves. (oncologybuddies.com)
  • These tumours mostly occur in the major salivary glands and the minor salivary glands of the mouth but can also occur where there are other minor salivary glands, such as the nose and sinuses, pharynx, larynx or trachea. (oncologybuddies.com)
  • Salivary gland tumours, also known as mucous gland adenomas or neoplasms, are tumours that form in the tissues of salivary glands.The salivary glands are classified as major or minor.The major salivary glands consist of the parotid, submandibular, and sublingual glands. (indianvartha.com)
  • Conclusion: Although the majority of patients with clinical early-stage ACC of the major salivary glands have favorable prognosis, a significant percentage of patients will develop DM. (indianvartha.com)
  • Anatomic extent of lymph node metastases as an independent prognosticator in node-positive major salivary gland carcinoma: A study of the US SEER database and a Chinese multicenter cohort. (uchicago.edu)
  • Schematic showing the major salivary glands. (librepathology.org)
  • There are more commonly found in major salivary glands, being associated to the submandibular gland in 80%, the parotid gland in 6-20% and the sublingual or minor salivary glands in only 2% of cases 1,3-4 . (bvsalud.org)
  • Mucoepidermoid carcinoma is the most common salivary gland malignancy in children. (medscape.com)
  • Tobacco and alcohol, which are highly associated with head and neck squamous cell carcinoma, have not been shown to play a role in the development of malignancies of the salivary glands. (medscape.com)
  • The prevalence of salivary gland carcinoma has increased [3]. (waocp.com)
  • MR images of 22 healthy subjects and 21 patients with histopathologically confirmed disorders of the submandibular gland (five pleomorphic adenomas, two hemangiomas, two malignant lymphomas, one adenoid cystic carcinoma, one squamous cell carcinoma, and 10 cases of sialadenitis) were reviewed. (fdocuments.net)
  • NUT Carcinoma of the Salivary Glands: Clinicopathologic and Molecular Analysis of 3 Cases and a Survey of NUT Expression in Salivary Gland Carcinomas. (icr.ac.uk)
  • This is the first small series on salivary NC highlighting the importance to include this rare disease in the differential diagnosis of poorly differentiated salivary gland carcinomas and in cases of presumable poorly differentiated carcinoma of unknown origin. (icr.ac.uk)
  • Some people develop adenoid cystic carcinoma in the gland that produces tears. (indianvartha.com)
  • Whole-Exome Sequencing of Salivary Gland Mucoepidermoid Carcinoma. (uchicago.edu)
  • Successful diagnosis and treatment of patients with salivary gland tumors require a thorough understanding of tumor etiology, biologic behavior of each tumor type, and salivary gland anatomy. (medscape.com)
  • This study is a retrospective descriptive study in which the records of patients with salivary gland tumors referred to the Radiotherapy and Oncology Center of Namazi Hospital from 2005 to 2015 were reviewed. (waocp.com)
  • Obtaining reliable pre-operative diagnosis is crucial in planning treatment for patients with salivary gland tumors. (tmu.edu.tw)
  • A retrospective analysis of the period between 1992 and 2011 was carried out to review the cases of patients with salivary gland tumors. (tmu.edu.tw)
  • Dentists are involved with aspects of salivary gland function in several ways, such as diagnosing problems involving the major and minor salivary glands, in the management of oral dryness associated with salivary problems, in the treatment of caries and periodontal disease resulting from decreased salivary flow, and in controlling salivation during restorative procedures. (medscape.com)
  • That is, as the size of the gland decreases, the incidence of malignancy of a tumor in the gland increases in approximately these proportions. (medscape.com)
  • The most common tumor of the parotid gland is the pleomorphic adenoma, which represents about 60% of all parotid neoplasms, as seen in the image below. (medscape.com)
  • In the multicellular theory, each tumor type is associated with a specific differentiated cell of origin within the salivary gland unit. (medscape.com)
  • Pleomorphic adenoma makes up 36% of all submandibular tumors and is the most frequent benign submandibular tumor.9.5% to 14.7% of all salivary gland tumors are minor salivary gland tumors, with the palate being the most often affected area. (medtigo.com)
  • The outcome of benign salivary gland tumors varies greatly depending on the tumor histology, with tumor progression and recurrence rates. (medtigo.com)
  • Demographic and Pathologic Characteristics of the 157 Patients with Salivary Gland Tumor. (waocp.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • Although the tumor occasionally occurs in the periparotid lymph nodes, it is rare in the other salivary glands. (stubensaenger.de)
  • You may need this surgery if a tumor forms in your parotid gland. (stubensaenger.de)
  • Warthin's tumor, also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing abundant lymphocytes and germinal centers. (stubensaenger.de)
  • Initially described in 1929, Warthin's tumor is a benign neoplasm predominantly found in the parotid gland of the salivary glands. (stubensaenger.de)
  • Site of the primary tumor was the parotid (7), sublingual (2), and submandibular (1) glands. (icr.ac.uk)
  • The most common type of salivary gland tumor is a slow-growing noncancerous (benign) tumor of the parotid gland. (medlineplus.gov)
  • The tumor gradually increases the size of the gland. (medlineplus.gov)
  • This patient has a large right-sided parotid salivary gland tumor. (msdmanuals.com)
  • Mammary neoplasms are described as the third most common type of feline tumor, after haematopoietic and skin tumors, and present a challenge for clinicians because the prognosis for feline mammary tumors ranges from guarded to poor. (usp.br)
  • Lipomas represent about 1 to 5 percent of all neoplasms of the oral cavity. (aafp.org)
  • It also separates the sublingual space (and oral cavity ) from the submandibular space . (radiopaedia.org)
  • Although the oral cavity and upper lip are the most common sites, they can develop in any region of the oral cavity that contains minor salivary glands. (bvsalud.org)
  • Although the upper lip and the buccal mucosa are the most frequently affected sites, they may develop in any part of the oral cavity that contains minor salivary glands 1-5 . (bvsalud.org)
  • A good rule of thumb is that the likelihood of an SGT being malignant is inversely proportional to the size of the gland from which it originates. (medscape.com)
  • From the infancy of surgical intervention, salivary gland surgery was limited to the treatment of ranulas and oral calculi, with the first recorded salivary surgery being a ranula excision performed by Guy de Chauliac of France in 1363. (medscape.com)
  • Complete excision of the pseudocyst with the affected salivary gland is associated with the least likelihood of recurrence. (aafp.org)
  • We almost always recommend excision of salivary neoplasms because even non-cancerous ones can transform into cancers. (oncologybuddies.com)
  • The salivary glands exist as larger named "major" glands and also as many widely dispersed "minor" glands that exist throughout the upper aerodigestive submucosa (ie, palate, lip, pharynx, nasopharynx, larynx, and parapharyngeal space). (medscape.com)
  • the remaining SGTs arise in the submandibular, sublingual, and minor salivary glands. (medscape.com)
  • The minor salivary glands comprise 600-1000 small glands distributed throughout the upper aerodigestive tract. (medscape.com)
  • Among salivary gland neoplasms, 80% arise in the parotid glands, 10-15% arise in the submandibular glands, and the remainder arise in the sublingual and minor salivary glands. (medscape.com)
  • Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
  • They can be present in different locations and have different histologies, including the sublingual, parotid, minor salivary glands and submandibular. (medtigo.com)
  • These tumors may arise from 6 major and numerous minor salivary glands. (waocp.com)
  • Less commonly, the submandibular gland or the minor salivary glands of the mouth may be involved. (aafp.org)
  • The salivary system is composed of 3 major gland sets and multiple minor glands. (medscape.com)
  • Approximately 1000 minor glands, localized to the cheeks, lips, and other intraoral mucosa, contribute about 7% to the whole saliva volume. (medscape.com)
  • The minor glands are primarily mucous producing, except those under the tongue, which produce serous fluid. (medscape.com)
  • We have both major and minor salivary glands secreting saliva into the mouth. (oncologybuddies.com)
  • The minor salivary glands are many, about 8000, and are single salivary units which open directly into the mouth, mostly situated on the inside lips, cheeks, hard and soft palates. (oncologybuddies.com)
  • The minor salivary glands and submandibular glands are largely responsible for the saliva in your mouth at rest, when you're not eating. (oncologybuddies.com)
  • While it is difficult to draw any conclusion for non-parotid gland tumors, surgical intervention should be recommended in patients with parotid tumors clinically suspected to be malignant, and all submandibular, sublingual and minor salivary gland tumors. (tmu.edu.tw)
  • Eighty percent of all salivary gland tumors arise in the parotid gland, 10% in the submandibular gland, and the remaining 10% in the minor salivary gland and sublingual gland (2). (fdocuments.net)
  • Osborne specializeS in parotid, submandibular, sublingual and minor salivary gland surgery. (stubensaenger.de)
  • These are called the minor salivary glands. (medlineplus.gov)
  • Rare: 2.3% of benign salivary tumors 6 th decade M:F = 1:1 Parotid: 78% Submandibular gland: 9% Minor salivary glands: palate, buccal mucosa, tongue. (slideserve.com)
  • Although rare, sialolithiasis can also occur in the minor salivary glands. (bvsalud.org)
  • This study presents three cases of sialolithiasis of minor salivary glands of the upper and lower lip, addresses their clinical characteristics and correlation with microscopic findings, diagnosis and treatment plans. (bvsalud.org)
  • Clinically, a patient with minor salivary gland sialolithiasis usually presents with a palpable, firm, submucosal nodule. (bvsalud.org)
  • The aim of this study was to report three rare cases of minor salivary gland sialolithiasis, which were treated surgically. (bvsalud.org)
  • Contrast may cause intense and prolonged enhancement of the thyroid gland which interferes with radioactive iodine nuclear medicine studies. (vdocument.in)
  • Serous demilunes = mucinous gland with "cap" consisting of a serous glandular component. (librepathology.org)
  • Sialolithiasis, or salivary calculus, is a disease of the salivary glands, characterized by the formation of mineralized structures within the excretory salivary ducts or the glandular parenchyma. (bvsalud.org)
  • The sublingual space is a fascial space of the head and neck (sometimes also termed fascial spaces or tissue spaces). (wikipedia.org)
  • Salivary gland tumors (SGTs) are uncommon and represent 2-3% of head and neck neoplasms. (medscape.com)
  • Additionally, clinical workup should aim to exclude malignant neoplasms originating from the salivary tissue or malignancies that originate in the mucosal or cutaneous lining of the head and neck region but may exhibit contiguous or metastatic involvement of salivary tissue. (medscape.com)
  • Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
  • Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
  • Salivary gland tumors are rare tumors that account for 3 to 4% of head and neck neoplasms. (waocp.com)
  • They account for 3 to 4% of head and neck neoplasms. (waocp.com)
  • Significant abnormality or disease of the salivary glands, such as that associated with Sjögren syndrome or neoplasm, necessitates additional evaluation by an otolaryngologist or an otolaryngologist/head and neck surgeon for comprehensive treatment of the gland pathology itself. (medscape.com)
  • Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
  • Pleomorphic, cystic, and canalicular adenomas are the three most typical benign small salivary gland tumors. (medtigo.com)
  • The most common malignant primary neoplasms are adenoid cystic and mucoepidermoid carcinomas. (oncologybuddies.com)
  • Adenoid cystic carcinomas are a high-grade neoplasm that has a propensity to invade and spread along nerves and therefore has a higher rate of local recurrence and/or distant metastasis, particularly to the lungs. (oncologybuddies.com)
  • This theory more logically explains neoplasms that contain multiple discrete cell types, such as pleomorphic adenomas and Warthin tumors. (medscape.com)
  • Salivary gland malignancies have been related in studies to former radiation exposure, with pleomorphic adenomas accounting for 50% of radiation-induced tumors. (medtigo.com)
  • Eighty percent of salivary gland tumours occur in the parotid gland, 80% of these are non-cancerous and 80% are pleomorphic adenomas. (oncologybuddies.com)
  • Sialolithiasis is the formation of stones within the salivary gland or ducts that drain the salivary gland, and it is the most common disease of the salivary glands, [1] affecting 12 in 1000 of the adult population. (annalsafrmed.org)
  • Common parotid neoplasms. (medscape.com)
  • Radiation therapy in low doses has been associated with the development of parotid neoplasms 15-20 years after treatment. (medscape.com)
  • Jan 21, 2021 Parotid neoplasms account for 80 of salivary neoplasms. (stubensaenger.de)
  • This study was designed to investigate the factors affecting the prognosis of salivary gland tumors. (waocp.com)
  • Treatment is based on surgical removal of both the sialolith and the gland involved, with a good prognosis 2-4 . (bvsalud.org)
  • The parotids produce the most fluid saliva, as they are composed of serous acini, with the sublingual gland producing mucus from mucous acini. (medscape.com)
  • The submandibular glands produce both serous and mucous saliva. (medscape.com)
  • Serous glands - lower viscosity, acini (lobules). (librepathology.org)
  • Serous ~90% of gland. (librepathology.org)
  • Pathology arising from the sublingual gland is rare, however, sublingual gland neoplasms are predominantly malignant and thus important to recognize. (wikipedia.org)
  • Submandibular gland (ouhsc.edu) - from a Pathology Quiz . (librepathology.org)
  • Salivary glands empty saliva into the mouth through ducts that open at various places in the mouth. (medlineplus.gov)
  • Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. (uchicago.edu)
  • ALDH/CD44 identifies uniquely tumorigenic cancer stem cells in salivary gland mucoepidermoid carcinomas. (uchicago.edu)
  • Salivary gland-type tumors of the breast: a spectrum of benign and malignant tumors including "triple negative carcinomas" of low malignant potential. (uchicago.edu)
  • [3] , [5] Submandibular sialolithiasis is more common as its saliva is more alkaline, has an increased concentration of calcium and phosphate and has a higher mucous content than saliva of the parotid and sublingual glands. (annalsafrmed.org)
  • Its boundaries are: the mucosa of the floor of mouth and the tongue superiorly the mylohyoid muscle inferiorly the medial surface of the mandible anterolaterally the muscles along the base of the tongue (geniohyoid and genioglossus muscles) posteriorly medially, the intrinsic muscles of the tongue and genioglossus separate the two halves of the sublingual space. (wikipedia.org)
  • the deep part of the submandibular gland and the submandibular duct (Wharton's duct) some extrinsic tongue muscle fibers. (wikipedia.org)
  • A sublingual abscess may elevate the tongue and cause drooling or dysphagia (difficulty swallowing). (wikipedia.org)
  • The sublingual glands, under the tongue, produce about 5% of the total oral saliva. (medscape.com)
  • and the sublingual gland under the tongue. (oncologybuddies.com)
  • Ultrasound of the soft tissues of the neck including thyroid, parathyroid, parotid and other salivary glands, lymph nodes, cysts, etc. is coded as CPT® 76536. (vdocument.in)
  • In addition, the submandibular duct is longer and the gland has an antigravity flow. (annalsafrmed.org)
  • Physical examination revealed a nontender, bluish, fluctuant sublingual mass with no obvious extension into the neck (see accompanying figure ) . (aafp.org)
  • range, 22 to 54 years) who were examined by precontrast and postcontrast MR imaging for various prob- lems of the face and neck not related to the submandibular gland or to the floor of the mouth. (fdocuments.net)
  • There are also hundreds of small salivary glands lining the rest of the mouth. (medlineplus.gov)
  • Salivary gland neoplasms are abnormal cells growing in the salivary gland or in the ducts that drain the glands. (medtigo.com)
  • In the histological classification of salivary gland cancers by WHO in 2005, there were 10 subtypes in the benign group and 24 subtypes in the malignant group, and benign subtypes are 5 to 7 times more common than malignant types and most of them (more than 80%) are PA (pleomorphic adenoma) [4]. (waocp.com)
  • Pleomorphic adenoma is the most common intraoral benign neoplasm. (msdmanuals.com)
  • An estimated 700 deaths (0.4 per 100,000 for males and 0.2 per 100,000 for females) related to salivary gland tumors occur annually. (medscape.com)
  • Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (medscape.com)
  • Less than 5% of occurrences of salivary gland tumors occur in children, and most of these tumors tend to be benign and vascular. (medtigo.com)
  • [ 7 ] age-related decline in saliva output was found to occur in the stimulated parotid, unstimulated submandibular/sublingual, and stimulated submandibular/sublingual glands. (medscape.com)
  • Additional research suggests that changes may occur in the viscoelasticity of saliva with aging, particularly in saliva produced by the submandibular and sublingual glands. (medscape.com)
  • Approximately 80% occur in the submandibular gland, followed by the parotid and sublingual glands. (bvsalud.org)
  • A periapical abscess may spread into the sublingual space if the apex of the tooth is above the level of attachment of mylohyoid, and the infection erodes through the lingual cortical plate of the mandible. (wikipedia.org)
  • Gout is the only systemic disorder known to predispose to salivary gland stone formation although in gout the stones are made predominantly of uric acid. (annalsafrmed.org)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
  • Saliva from the sublingual gland drains through several small excretory ducts in the floor of the mouth. (wikipedia.org)
  • Signs and symptoms of a sublingual space infection might include a firm, painful swelling in the anterior part of the floor of the mouth. (wikipedia.org)
  • The salivary glands are located around the mouth. (medlineplus.gov)
  • Two submandibular glands are under the floor of the mouth on both sides of the back of the jaw. (medlineplus.gov)
  • Two sublingual glands are under the floor of the mouth next to the jaw on each side. (medlineplus.gov)
  • Firm, usually painless swelling in one of the salivary glands (in front of the ears, under the chin, or on the floor of the mouth). (medlineplus.gov)
  • The salivary glands are exocrine glands that produce saliva to moisten the mouth, aid digestion, and help protect the teeth from decay. (annalsafrmed.org)
  • Imaging the floor of the mouth and the sublingual space. (radiopaedia.org)
  • Chemotherapy may be used when the disease has spread beyond the salivary glands. (medlineplus.gov)
  • Offering unparalleled coverage of this key area, Surgery of the Salivary Glands provides an in-depth, authoritative review of salivary gland disease and treatment . (bookbaz.ir)
  • A number of different cellular signaling and regulatory systems in the acini and ducts are involved with saliva formation when the glands are stimulated by gustatory, masticatory, and psychic stimulation. (medscape.com)
  • Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
  • The sublingual space contains: a number of blood vessels and nerves, e.g. the lingual artery and nerve, the hypoglossal nerve and the glossopharyngeal nerve. (wikipedia.org)
  • manipulations related to dentistry/orthodontics, telehealth, home care, extraocular muscles, small-sized structured (para-aortic body, glomus, pineal body, lacrimal gland), nasal turbinate were excluded, as well as codes containing both - inclusion term and term indicating its non-traumatic origin). (ohdsi.org)