The ability to detect chemicals through gustatory receptors in the mouth, including those on the TONGUE; the PALATE; the PHARYNX; and the EPIGLOTTIS.
The process by which the nature and meaning of gustatory stimuli are recognized and interpreted by the brain. The four basic classes of taste perception are salty, sweet, bitter, and sour.
Small sensory organs which contain gustatory receptor cells, basal cells, and supporting cells. Taste buds in humans are found in the epithelia of the tongue, palate, and pharynx. They are innervated by the CHORDA TYMPANI NERVE (a branch of the facial nerve) and the GLOSSOPHARYNGEAL NERVE.
A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.
A branch of the facial (7th cranial) nerve which passes through the middle ear and continues through the petrotympanic fissure. The chorda tympani nerve carries taste sensation from the anterior two-thirds of the tongue and conveys parasympathetic efferents to the salivary glands.
The 9th cranial nerve. The glossopharyngeal nerve is a mixed motor and sensory nerve; it conveys somatic and autonomic efferents as well as general, special, and visceral afferents. Among the connections are motor fibers to the stylopharyngeus muscle, parasympathetic fibers to the parotid glands, general and taste afferents from the posterior third of the tongue, the nasopharynx, and the palate, and afferents from baroreceptors and CHEMORECEPTOR CELLS of the carotid sinus.
The sensory ganglion of the facial (7th cranial) nerve. The geniculate ganglion cells send central processes to the brain stem and peripheral processes to the taste buds in the anterior tongue, the soft palate, and the skin of the external auditory meatus and the mastoid process.
An autonomic disorder characterized by excessive sweating of the forehead, upper lip, perioral region, or sternum subsequent to gustatory stimuli. The auriculotemporal syndrome features facial flushing or sweating limited to the distribution of the auriculotemporal nerve and may develop after trauma to the parotid gland, in association with PAROTID NEOPLASMS, or following their surgical removal. (From Ann Neurol 1997 Dec;42(6):973-5)
Conditions characterized by an alteration in gustatory function or perception. Taste disorders are frequently associated with OLFACTION DISORDERS. Additional potential etiologies include METABOLIC DISEASES; DRUG TOXICITY; and taste pathway disorders (e.g., TASTE BUD diseases; FACIAL NERVE DISEASES; GLOSSOPHARYNGEAL NERVE DISEASES; and BRAIN STEM diseases).
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
The minimum concentration at which taste sensitivity to a particular substance or food can be perceived.
GRAY MATTER located in the dorsomedial part of the MEDULLA OBLONGATA associated with the solitary tract. The solitary nucleus receives inputs from most organ systems including the terminations of the facial, glossopharyngeal, and vagus nerves. It is a major coordinator of AUTONOMIC NERVOUS SYSTEM regulation of cardiovascular, respiratory, gustatory, gastrointestinal, and chemoreceptive aspects of HOMEOSTASIS. The solitary nucleus is also notable for the large number of NEUROTRANSMITTERS which are found therein.
A nonreducing disaccharide composed of GLUCOSE and FRUCTOSE linked via their anomeric carbons. It is obtained commercially from SUGARCANE, sugar beet (BETA VULGARIS), and other plants and used extensively as a food and a sweetener.
Substances added to foods and medicine to improve the quality of taste.
Cells specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptor cells may monitor external stimuli, as in TASTE and OLFACTION, or internal stimuli, such as the concentrations of OXYGEN and CARBON DIOXIDE in the blood.
A ubiquitous sodium salt that is commonly used to season food.
Flavoring agent and non-nutritive sweetener.
The selection of one food over another.
Collective name for a group of external MECHANORECEPTORS and chemoreceptors manifesting as sensory structures in ARTHROPODS. They include cuticular projections (setae, hairs, bristles), pores, and slits.
Substances that sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. (From Random House Unabridged Dictionary, 2d ed)
One of the FLAVORING AGENTS used to impart a meat-like flavor.
The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
Biological actions and events that constitute the functions of the NERVOUS SYSTEM.
The ability to detect scents or odors, such as the function of OLFACTORY RECEPTOR NEURONS.
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
Traumatic injuries to the VAGUS NERVE. Because the vagus nerve innervates multiple organs, injuries in the nerve fibers may result in any gastrointestinal organ dysfunction downstream of the injury site.
Specialized organs adapted for the reception of stimuli by the NERVOUS SYSTEM.
The psychoanalytic concept that man instinctively seeks to avoid pain and discomfort and strives for gratification and pleasure.
A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
Behavioral responses or sequences associated with eating including modes of feeding, rhythmic patterns of eating, and time intervals.
The front part of the hindbrain (RHOMBENCEPHALON) that lies between the MEDULLA and the midbrain (MESENCEPHALON) ventral to the cerebellum. It is composed of two parts, the dorsal and the ventral. The pons serves as a relay station for neural pathways between the CEREBELLUM to the CEREBRUM.
The process by which the nature and meaning of olfactory stimuli, such as odors, are recognized and interpreted by the brain.
Complete or severe loss of the subjective sense of taste, frequently accompanied by OLFACTION DISORDERS.
Specialized afferent neurons capable of transducing sensory stimuli into NERVE IMPULSES to be transmitted to the CENTRAL NERVOUS SYSTEM. Sometimes sensory receptors for external stimuli are called exteroceptors; for internal stimuli are called interoceptors and proprioceptors.
Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.
A response to a cue that is instrumental in avoiding a noxious experience.
Neurons which conduct NERVE IMPULSES to the CENTRAL NERVOUS SYSTEM.
Activities designed to attract the attention or favors of another.
A sensory branch of the MANDIBULAR NERVE, which is part of the trigeminal (5th cranial) nerve. The lingual nerve carries general afferent fibers from the anterior two-thirds of the tongue, the floor of the mouth, and the mandibular gingivae.
Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
A salt of lithium that has been used experimentally as an immunomodulator.
Clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons. Sensory ganglia may also have intrinsic interneurons and non-neuronal supporting cells.
Proteins, usually projecting from the cilia of olfactory receptor neurons, that specifically bind odorant molecules and trigger responses in the neurons. The large number of different odorant receptors appears to arise from several gene families or subfamilies rather than from DNA rearrangement.
The observable response an animal makes to any situation.
Loss of or impaired ability to smell. This may be caused by OLFACTORY NERVE DISEASES; PARANASAL SINUS DISEASES; viral RESPIRATORY TRACT INFECTIONS; CRANIOCEREBRAL TRAUMA; SMOKING; and other conditions.
A plant genus of the family FABACEAE (sometimes classified as Papilionaceae). Members contain LECTINS.
Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.
A species of fruit fly much used in genetics because of the large size of its chromosomes.
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
The desire for FOOD generated by a sensation arising from the lack of food in the STOMACH.
The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and SALIVARY GLANDS, and convey afferent information for TASTE from the anterior two-thirds of the TONGUE and for TOUCH from the EXTERNAL EAR.
Behaviors associated with the ingesting of water and other liquids; includes rhythmic patterns of drinking (time intervals - onset and duration), frequency and satiety.
A species of the family Ranidae (true frogs). The only anuran properly referred to by the common name "bullfrog", it is the largest native anuran in North America.
The trihydrate sodium salt of acetic acid, which is used as a source of sodium ions in solutions for dialysis and as a systemic and urinary alkalizer, diuretic, and expectorant.
The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
The structure that forms the roof of the mouth. It consists of the anterior hard palate (PALATE, HARD) and the posterior soft palate (PALATE, SOFT).
A movable fold suspended from the posterior border of the hard palate. The uvula hangs from the middle of the lower border.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
A heterotrimeric GTP-binding protein that mediates the light activation signal from photolyzed rhodopsin to cyclic GMP phosphodiesterase and is pivotal in the visual excitation process. Activation of rhodopsin on the outer membrane of rod and cone cells causes GTP to bind to transducin followed by dissociation of the alpha subunit-GTP complex from the beta/gamma subunits of transducin. The alpha subunit-GTP complex activates the cyclic GMP phosphodiesterase which catalyzes the hydrolysis of cyclic GMP to 5'-GMP. This leads to closure of the sodium and calcium channels and therefore hyperpolarization of the rod cells. EC 3.6.1.-.
Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA.
Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system.
An object or a situation that can serve to reinforce a response, to satisfy a motive, or to afford pleasure.
ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.
A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.
Area of the parietal lobe concerned with receiving sensations such as movement, pain, pressure, position, temperature, touch, and vibration. It lies posterior to the central sulcus.
Sweet food products combining cane or beet sugars with other carbohydrates and chocolate, milk, eggs, and various flavorings. In the United States, candy refers to both sugar- and cocoa-based confections and is differentiated from sweetened baked goods; elsewhere the terms sugar confectionary, chocolate confectionary, and flour confectionary (meaning goods such as cakes and pastries) are used.
Chemical substances, excreted by an organism into the environment, that elicit behavioral or physiological responses from other organisms of the same species. Perception of these chemical signals may be olfactory or by contact.
Common name for Carassius auratus, a type of carp (CARPS).
Neural tracts connecting one part of the nervous system with another.
The resection or removal of the nerve to an organ or part. (Dorland, 28th ed)
Natural recurring desire for food. Alterations may be induced by APPETITE DEPRESSANTS or APPETITE STIMULANTS.
The sensory fibers innervating the viscera.
Sucrose present in the diet. It is added to food and drinks as a sweetener.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.
Paired sense organs connected to the anterior segments of ARTHROPODS that help them navigate through the environment.
An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
An outbred strain of rats developed in 1915 by crossing several Wistar Institute white females with a wild gray male. Inbred strains have been derived from this original outbred strain, including Long-Evans cinnamon rats (RATS, INBRED LEC) and Otsuka-Long-Evans-Tokushima Fatty rats (RATS, INBRED OLETF), which are models for Wilson's disease and non-insulin dependent diabetes mellitus, respectively.
A salamander found in Mexican mountain lakes and accounting for about 30 percent of the urodeles used in research. The axolotl remains in larval form throughout its life, a phenomenon known as neoteny.
A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology.
Nerve structures through which impulses are conducted from a nerve center toward a peripheral site. Such impulses are conducted via efferent neurons (NEURONS, EFFERENT), such as MOTOR NEURONS, autonomic neurons, and hypophyseal neurons.
Insect members of the superfamily Apoidea, found almost everywhere, particularly on flowers. About 3500 species occur in North America. They differ from most WASPS in that their young are fed honey and pollen rather than animal food.
Homogeneous liquid preparations that contain one or more chemical substances dissolved, i.e., molecularly dispersed, in a suitable solvent or mixture of mutually miscible solvents. For reasons of their ingredients, method of preparation, or use, they do not fall into another group of products.
Behavioral response associated with the achieving of gratification.
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)
A technique that labels specific sequences in whole chromosomes by in situ DNA chain elongation or PCR (polymerase chain reaction).
Proteins found in any species of insect.
Set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex. It includes the OLFACTORY NERVE; OLFACTORY BULB; OLFACTORY TRACT; OLFACTORY TUBERCLE; ANTERIOR PERFORATED SUBSTANCE; and OLFACTORY CORTEX.
The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
The volatile portions of substances perceptible by the sense of smell. (Grant & Hackh's Chemical Dictionary, 5th ed)
A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension, and NEUROPATHIC PAIN. The receptor comprises three P2X3 subunits. The P2X3 subunits are also associated with P2X2 RECEPTOR subunits in a heterotrimeric receptor variant.
A phosphoinositide phospholipase C subtype that is primarily regulated by its association with HETEROTRIMERIC G-PROTEINS. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of C-terminal extension of 400 residues.
The consumption of liquids.
Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.
Animal searching behavior. The variable introductory phase of an instinctive behavior pattern or sequence, e.g., looking for food, or sequential courtship patterns prior to mating.
A general term referring to the learning of some particular response.
A class of ligand-gated ion channel receptors that have specificity for GLUTAMATE. They are distinct from METABOTROPIC GLUTAMATE RECEPTORS which act through a G-protein-coupled mechanism.
The use of mental images produced by the imagination as a form of psychotherapy. It can be classified by the modality of its content: visual, verbal, auditory, olfactory, tactile, gustatory, or kinesthetic. Common themes derive from nature imagery (e.g., forests and mountains), water imagery (e.g., brooks and oceans), travel imagery, etc. Imagery is used in the treatment of mental disorders and in helping patients cope with other diseases. Imagery often forms a part of HYPNOSIS, of AUTOGENIC TRAINING, of RELAXATION TECHNIQUES, and of BEHAVIOR THERAPY. (From Encyclopedia of Human Behavior, vol. 4, pp29-30, 1994)
Area in the hypothalamus bounded medially by the mammillothalamic tract and the anterior column of the FORNIX (BRAIN). The medial edge of the INTERNAL CAPSULE and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE.
Inosine 5'-Monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
Lectins purified from the germinating seeds of common wheat (Triticum vulgare); these bind to certain carbohydrate moieties on cell surface glycoproteins and are used to identify certain cell populations and inhibit or promote some immunological or physiological activities. There are at least two isoforms of this lectin.
Use of electric potential or currents to elicit biological responses.
The functional hereditary units of INSECTS.
The consumption of edible substances.
A diet which contains very little sodium chloride. It is prescribed by some for hypertension and for edematous states. (Dorland, 27th ed)
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
A species of nematode that is widely used in biological, biochemical, and genetic studies.
Abnormal passage communicating with the STOMACH.
A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
The principle that items experienced together enter into a connection, so that one tends to reinstate the other.
The process of laying or shedding fully developed eggs (OVA) from the female body. The term is usually used for certain INSECTS or FISHES with an organ called ovipositor where eggs are stored or deposited before expulsion from the body.
Characteristic properties and processes of the NERVOUS SYSTEM as a whole or with reference to the peripheral or the CENTRAL NERVOUS SYSTEM.
Trehalose is a non-reducing disaccharide composed of two glucose molecules linked by an alpha, alpha-1,1-glycosidic bond, naturally found in some plants and microorganisms, serving as a cryoprotectant and providing cellular protection against various stress conditions.
Proteins from the nematode species CAENORHABDITIS ELEGANS. The proteins from this species are the subject of scientific interest in the area of multicellular organism MORPHOGENESIS.
Act of eliciting a response from a person or organism through physical contact.
Substances produced from the reaction between acids and bases; compounds consisting of a metal (positive) and nonmetal (negative) radical. (Grant & Hackh's Chemical Dictionary, 5th ed)
A subgroup of TRP cation channels named after melastatin protein. They have the TRP domain but lack ANKYRIN repeats. Enzyme domains in the C-terminus leads to them being called chanzymes.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
A mass of KERATIN-producing squamous EPITHELIUM that resembles an inverted (suck-in) bag of skin in the MIDDLE EAR. It arises from the eardrum (TYMPANIC MEMBRANE) and grows into the MIDDLE EAR causing erosion of EAR OSSICLES and MASTOID that contains the INNER EAR.
Common name of the order Siluriformes. This order contains many families and over 2,000 species, including venomous species. Heteropneustes and Plotosus genera have dangerous stings and are aggressive. Most species are passive stingers.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Signals for an action; that specific portion of a perceptual field or pattern of stimuli to which a subject has learned to respond.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
The discharge of saliva from the SALIVARY GLANDS that keeps the mouth tissues moist and aids in digestion.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
Insects of the suborder Heterocera of the order LEPIDOPTERA.
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES. Carbohydrates are composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n.
The process by which the nature and meaning of sensory stimuli are recognized and interpreted.
Renewal or physiological repair of damaged nerve tissue.
Differential response to different stimuli.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Learning situations in which the sequence responses of the subject are instrumental in producing reinforcement. When the correct response occurs, which involves the selection from among a repertoire of responses, the subject is immediately reinforced.
Neural nuclei situated in the septal region. They have afferent and cholinergic efferent connections with a variety of FOREBRAIN and BRAIN STEM areas including the HIPPOCAMPAL FORMATION, the LATERAL HYPOTHALAMUS, the tegmentum, and the AMYGDALA. Included are the dorsal, lateral, medial, and triangular septal nuclei, septofimbrial nucleus, nucleus of diagonal band, nucleus of anterior commissure, and the nucleus of stria terminalis.
Sexual activities of animals.
The removal or interruption of some part of the sympathetic nervous system for therapeutic or research purposes.
Full gratification of a need or desire followed by a state of relative insensitivity to that particular need or desire.
A genus of silkworm MOTHS in the family Bombycidae of the order LEPIDOPTERA. The family contains a single species, Bombyx mori from the Greek for silkworm + mulberry tree (on which it feeds). A native of Asia, it is sometimes reared in this country. It has long been raised for its SILK and after centuries of domestication it probably does not exist in nature. It is used extensively in experimental GENETICS. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p519)
A genus of the family Muridae having three species. The present domesticated strains were developed from individuals brought from Syria. They are widely used in biomedical research.
A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)
A region extending from the PONS & MEDULLA OBLONGATA through the MESENCEPHALON, characterized by a diversity of neurons of various sizes and shapes, arranged in different aggregations and enmeshed in a complicated fiber network.
The lower portion of the BRAIN STEM. It is inferior to the PONS and anterior to the CEREBELLUM. Medulla oblongata serves as a relay station between the brain and the spinal cord, and contains centers for regulating respiratory, vasomotor, cardiac, and reflex activities.
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS. It may play an essential role in regulating myocardial contractile response.
The anterior of the three primitive cerebral vesicles of the embryonic brain arising from the NEURAL TUBE. It subdivides to form DIENCEPHALON and TELENCEPHALON. (Stedmans Medical Dictionary, 27th ed)
Slender-bodies diurnal insects having large, broad wings often strikingly colored and patterned.
Electrodes with an extremely small tip, used in a voltage clamp or other apparatus to stimulate or record bioelectric potentials of single cells intracellularly or extracellularly. (Dorland, 28th ed)
Paired bodies containing mostly GRAY MATTER and forming part of the lateral wall of the THIRD VENTRICLE of the brain.
A set of forebrain structures common to all mammals that is defined functionally and anatomically. It is implicated in the higher integration of visceral, olfactory, and somatic information as well as homeostatic responses including fundamental survival behaviors (feeding, mating, emotion). For most authors, it includes the AMYGDALA; EPITHALAMUS; GYRUS CINGULI; hippocampal formation (see HIPPOCAMPUS); HYPOTHALAMUS; PARAHIPPOCAMPAL GYRUS; SEPTAL NUCLEI; anterior nuclear group of thalamus, and portions of the basal ganglia. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p744; NeuroNames, http://rprcsgi.rprc.washington.edu/neuronames/index.html (September 2, 1998)).
A species of the genus MACACA which typically lives near the coast in tidal creeks and mangrove swamps primarily on the islands of the Malay peninsula.
The act of making a selection among two or more alternatives, usually after a period of deliberation.
The process in which specialized SENSORY RECEPTOR CELLS transduce peripheral stimuli (physical or chemical) into NERVE IMPULSES which are then transmitted to the various sensory centers in the CENTRAL NERVOUS SYSTEM.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
Sodium chloride used in foods.
The relationships of groups of organisms as reflected by their genetic makeup.
Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.
Any substances taken in by the body that provide nourishment.
The time from the onset of a stimulus until a response is observed.
The measurement of magnetic fields over the head generated by electric currents in the brain. As in any electrical conductor, electric fields in the brain are accompanied by orthogonal magnetic fields. The measurement of these fields provides information about the localization of brain activity which is complementary to that provided by ELECTROENCEPHALOGRAPHY. Magnetoencephalography may be used alone or together with electroencephalography, for measurement of spontaneous or evoked activity, and for research or clinical purposes.
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Profound physical changes during maturation of living organisms from the immature forms to the adult forms, such as from TADPOLES to frogs; caterpillars to BUTTERFLIES.
Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.
Neurons in the OLFACTORY EPITHELIUM with proteins (RECEPTORS, ODORANT) that bind, and thus detect, odorants. These neurons send their DENDRITES to the surface of the epithelium with the odorant receptors residing in the apical non-motile cilia. Their unmyelinated AXONS synapse in the OLFACTORY BULB of the BRAIN.
Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).
Inbred C57BL mice are a strain of laboratory mice that have been produced by many generations of brother-sister matings, resulting in a high degree of genetic uniformity and homozygosity, making them widely used for biomedical research, including studies on genetics, immunology, cancer, and neuroscience.
Learning that is manifested in the ability to respond differentially to various stimuli.
Elements of limited time intervals, contributing to particular results or situations.
Drugs that bind to and activate excitatory amino acid receptors.
A meshlike structure composed of interconnecting nerve cells that are separated at the synaptic junction or joined to one another by cytoplasmic processes. In invertebrates, for example, the nerve net allows nerve impulses to spread over a wide area of the net because synapses can pass information in any direction.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
A monosaccharide in sweet fruits and honey that is soluble in water, alcohol, or ether. It is used as a preservative and an intravenous infusion in parenteral feeding.
A light microscopic technique in which only a small spot is illuminated and observed at a time. An image is constructed through point-by-point scanning of the field in this manner. Light sources may be conventional or laser, and fluorescence or transmitted observations are possible.
The minimum amount of stimulus energy necessary to elicit a sensory response.
Derivatives of ammonium compounds, NH4+ Y-, in which all four of the hydrogens bonded to nitrogen have been replaced with hydrocarbyl groups. These are distinguished from IMINES which are RN=CR2.
The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.
Learning that takes place when a conditioned stimulus is paired with an unconditioned stimulus.
The movement of cells or organisms toward or away from a substance in response to its concentration gradient.
Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
'Nerve tissue proteins' are specialized proteins found within the nervous system's biological tissue, including neurofilaments, neuronal cytoskeletal proteins, and neural cell adhesion molecules, which facilitate structural support, intracellular communication, and synaptic connectivity essential for proper neurological function.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.
A type VI intermediate filament protein expressed mostly in nerve cells where it is associated with the survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.
An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.
A state in which there is an enhanced potential for sensitivity and an efficient responsiveness to external stimuli.

Clinically benign parotid tumours: local dissection as an alternative to superficial parotidectomy in selected cases. (1/19)

In a personal series of 162 tumours, 101 were pleomorphic adenomas 28 of which were removed by elective local extra capsular dissection and 73 by a conventional nerve dissection. There were no recurrences in either group after a mean follow-up 10.3 years, range 3-21 years for local dissection and 8.3 years, range 3-22 years for nerve dissection. Frey's syndrome did not occur after local dissection but was present in 25% of patients after a nerve dissection. Of the 162 parotid lumps, 17 proved to be a carcinoma but only one was deemed suitable for a local removal, a low grade muco epidermoid carcinoma of the accessory lobe and no recurrence has occurred after 8 years. In benign disease, local dissection gives similar results to conventional nerve dissection with less morbidity and confirms that tumour recurrence cannot be ascribed to any properties of the tumour but lies in the hands of the surgeon and depends on the care with which the tumour is removed.  (+info)

Parotid swellings: report of 110 consecutive cases. (2/19)

Parotid swellings are uncommon. Over a twelve-year period, 110 cases of parotid swellings were treated at the Department of Plastic Surgery, Hospital Kuala Lumpur, of which 97 cases were histologically proven to be parotid tumours. 75% of these tumours were benign tumours, and 80% of the benign tumours were pleomorphic adenomas. Among the malignant tumours, 6 cases were adenoid cystic carcinoma and 5 were carcinoma ex-pleomorphic adenoma. There were equal number of male to female patients, with an age range of 14 to 83 years. There is a positive correlation between the final histological diagnosis and FNAC results in 74% of cases. Surgical treatment of choice for benign parotid tumours was near-total parotidectomy whilst for malignant tumours was total radical parotidectomy with sural nerve graft.  (+info)

Malignant pheochromocytoma lacking clinical features of catecholamine excess until the late stage. (3/19)

A malignant pheochromocytoma is described in a 71-year-old man. Osseous metastases became manifest 12 years after successful removal of the primary tumor which originated in paraganglionic tissue near the right adrenal gland. Although the patient had no symptoms of catecholamine excess initially, hypertension, tachycardia and excessive sweating appeared several months before his death, concomitantly with a sharp increase in noradrenaline secretion due to an accelerated growth of metastatic tumors. Since there is no histologic criterion of malignancy in this neoplasm, it would be prudent to consider every case of pheochromocytoma as potentially malignant and to follow-up carefully for a long time after removal of the primary tumor.  (+info)

Botulinum toxin for treatment of Frey's syndrome: report of two cases. (4/19)

Frey's syndrome is a phenomenon of hemifacial flushing and sweating after gustatory stimulus, usually secondary to surgical trauma over the parotid gland, although other injury mechanisms may be seen. It is accepted as a result of aberrant regeneration of facial autonomic nerve fibers. Treatment evolved from ineffective medical and surgical approaches to botulinum toxin. We evaluate the effectiveness and safety of botulinum toxin in the treatment of this complication in two patients.  (+info)

Treatment of compensatory gustatory hyperhidrosis with topical glycopyrrolate. (5/19)

Gustatory hyperhidrosis is facial sweating usually associated with the eating of hot spicy food or even smelling this food. Current options of treatment include oral anticholinergic drugs, the topical application of anticholinergics or aluminum chloride, and the injection of botulinum toxin. Thirteen patients have been treated to date with 1.5% or 2% topical glycopyrrolate. All patients had gustatory hyperhidrosis, which interfered with their social activities, after transthroacic endoscopic sympathectomy, and which was associated with compensatory focal hyperhidrosis. After applying topical glycopyrrolate, the subjective effect was excellent (no sweating after eating hot spicy food) in 10 patients (77%), and fair (clearly reduced sweating) in 3 patients (23%). All had reported incidents of being very embarrassed whilst eating hot spicy foods. Adverse effects included a mildly dry mouth and a sore throat in 2 patients (2% glycopyrrolate), a light headache in 1 patient (1.5% glycopyrrolate). The topical application of a glycopyrrolate pad appeared to be safe, efficacious, well tolerated, and a convenient method of treatment for moderate to severe symptoms of gustatory hyperhidrosis in post transthoracic endoscopic sympathectomy or sympathicotomy patients, with few side effects.  (+info)

Frey's syndrome after condylar fracture: case report. (6/19)

Frey's syndrome is the occurrence of hyperesthesia, flushing and warmth or sweating over the distribution of the auriculotemporal nerve and/or greater auricular nerve while eating foods that produce a strong salivary stimulus. Frey's syndrome is also known as auriculotemporal syndrome and gustatory sweating. We present a case of Frey's syndrome after a condylar fracture and its treatment by internal rigid fixation. A review of the literature is provided along with mention of a simple test (Minor's test) that can help in the diagnosis of this syndrome.  (+info)

Treatment of complications of parotid gland surgery. (7/19)

Although several reports in the literature have documented the surgical technique, and the oncological outcome achieved with parotidectomy, only a few articles have described the complications of parotid gland surgery and their management. Several complications have been reported in parotid surgery. We re-classified the complications of parotidectomy in intra-operative and post-operative (early and late). The commonest complications after parotidectomy are temporary or permanent facial palsy and Frey's syndrome.  (+info)

Frey syndrome prevalence after partial parotidectomy. (8/19)

INTRODUCTION: Frey syndrome is a sequela observed after parotidectomy and the reported incidence varies enormously in the literature. Diagnosis is evaluated by presence of the classic triad of gustatory sweating, heating and flushing while feeding and documented by Minor starch-iodine test. AIM: To evaluate the incidence of this syndrome in patients submitted to partial parotidectomy at Centro Otorrinolaringologico de Limeira, from 1994 to 2004, including presence of signs and symptoms and the surgical technique. MATERIAL AND METHOD: Fourteen patients undergoing partial parotidectomy with sternocleidomastoid muscle flap answered a questionnaire and were classified as positive or negative by Minor starch-iodine test in a clinical retrospective study. RESULTS: 21% of the patients presented symptoms and positive iodine test. CONCLUSION: Only the patients presenting clinical symptoms had a positive test and the adopted surgical technique was efficient due to low incidence of the syndrome.  (+info)

In a medical context, taste is the sensation produced when a substance in the mouth reacts with taste buds, which are specialized sensory cells found primarily on the tongue. The tongue's surface contains papillae, which house the taste buds. These taste buds can identify five basic tastes: salty, sour, bitter, sweet, and umami (savory). Different areas of the tongue are more sensitive to certain tastes, but all taste buds can detect each of the five tastes, although not necessarily equally.

Taste is a crucial part of our sensory experience, helping us identify and differentiate between various types of food and drinks, and playing an essential role in appetite regulation and enjoyment of meals. Abnormalities in taste sensation can be associated with several medical conditions or side effects of certain medications.

Taste perception refers to the ability to recognize and interpret different tastes, such as sweet, salty, sour, bitter, and umami, which are detected by specialized sensory cells called taste buds located on the tongue and other areas in the mouth. These taste signals are then transmitted to the brain, where they are processed and identified as specific tastes. Taste perception is an important sense that helps us to appreciate and enjoy food, and it also plays a role in our ability to detect potentially harmful substances in our diet.

A taste bud is a cluster of specialized sensory cells found primarily on the tongue, soft palate, and cheek that are responsible for the sense of taste. They contain receptor cells which detect specific tastes: sweet, salty, sour, bitter, and umami (savory). Each taste bud contains supporting cells and 50-100 taste receptor cells. These cells have hair-like projections called microvilli that come into contact with food or drink, transmitting signals to the brain to interpret the taste.

In medical terms, the tongue is a muscular organ in the oral cavity that plays a crucial role in various functions such as taste, swallowing, and speech. It's covered with a mucous membrane and contains papillae, which are tiny projections that contain taste buds to help us perceive different tastes - sweet, salty, sour, and bitter. The tongue also assists in the initial process of digestion by moving food around in the mouth for chewing and mixing with saliva. Additionally, it helps in forming words and speaking clearly by shaping the sounds produced in the mouth.

The chorda tympani nerve is a branch of the facial nerve (cranial nerve VII) that has both sensory and taste functions. It carries taste sensations from the anterior two-thirds of the tongue and sensory information from the oral cavity, including touch, temperature, and pain.

Anatomically, the chorda tympani nerve originates from the facial nerve's intermediate nerve, which is located in the temporal bone of the skull. It then travels through the middle ear, passing near the tympanic membrane (eardrum) before leaving the skull via the petrotympanic fissure. From there, it joins the lingual nerve, a branch of the mandibular division of the trigeminal nerve (cranial nerve V), which carries the taste and sensory information to the brainstem for processing.

Clinically, damage to the chorda tympani nerve can result in loss of taste sensation on the anterior two-thirds of the tongue and altered sensations in the oral cavity. This type of injury can occur during middle ear surgery or as a result of various medical conditions that affect the facial nerve or its branches.

The glossopharyngeal nerve, also known as the ninth cranial nerve (IX), is a mixed nerve that carries both sensory and motor fibers. It originates from the medulla oblongata in the brainstem and has several functions:

1. Sensory function: The glossopharyngeal nerve provides general sensation to the posterior third of the tongue, the tonsils, the back of the throat (pharynx), and the middle ear. It also carries taste sensations from the back one-third of the tongue.
2. Special visceral afferent function: The nerve transmits information about the stretch of the carotid artery and blood pressure to the brainstem.
3. Motor function: The glossopharyngeal nerve innervates the stylopharyngeus muscle, which helps elevate the pharynx during swallowing. It also provides parasympathetic fibers to the parotid gland, stimulating saliva production.
4. Visceral afferent function: The glossopharyngeal nerve carries information about the condition of the internal organs in the thorax and abdomen to the brainstem.

Overall, the glossopharyngeal nerve plays a crucial role in swallowing, taste, saliva production, and monitoring blood pressure and heart rate.

The geniculate ganglion is a sensory ganglion (a cluster of nerve cell bodies) located in the facial nerve (cranial nerve VII). It is responsible for the special sense of taste for the anterior two-thirds of the tongue and the sensation of skin over the external ear and parts of the face. The term "geniculate" means "knee-shaped," which describes the appearance of this part of the facial nerve.

Gustatory sweating, also known as Frey's syndrome, is a condition in which an individual experiences excessive sweating on the face, neck, and scalp while eating, especially spicy or strong-flavored foods. This unusual form of sweating occurs due to an abnormal cross-innervation between the sympathetic and parasympathetic nerves that supply the salivary glands and sweat glands in the skin of the face and neck.

Normally, when we eat, our body activates the parasympathetic nervous system to stimulate saliva production for digestion. In some individuals, this activation can cause an aberrant response where sympathetic nerve fibers are also activated, leading to sweating in the affected areas. This condition is often a result of damage or injury to the nerves in the face, such as after surgery (particularly facial nerve or parotid gland surgeries), trauma, or infection.

Taste disorders, also known as dysgeusia, refer to conditions that affect a person's ability to taste or distinguish between different tastes. These tastes include sweet, sour, salty, bitter, and umami (savory). Taste disorders can result from damage to the taste buds, nerves that transmit taste signals to the brain, or areas of the brain responsible for processing taste information.

Taste disorders can manifest in several ways, including:

1. Hypogeusia: Reduced ability to taste
2. Ageusia: Complete loss of taste
3. Dysgeusia: Distorted or altered taste perception
4. Phantogeusia: Tasting something that is not present
5. Parageusia: Unpleasant or metallic tastes in the mouth

Taste disorders can be caused by various factors, including damage to the tongue or other areas of the mouth, certain medications, infections, exposure to chemicals or radiation, and neurological conditions such as Bell's palsy or multiple sclerosis. In some cases, taste disorders may be a symptom of an underlying medical condition, such as diabetes or kidney disease.

Treatment for taste disorders depends on the underlying cause. If a medication is causing the disorder, adjusting the dosage or switching to a different medication may help. In other cases, treating the underlying medical condition may resolve the taste disorder. If the cause cannot be identified or treated, various therapies and strategies can be used to manage the symptoms of taste disorders.

Quinine is defined as a bitter crystalline alkaloid derived from the bark of the Cinchona tree, primarily used in the treatment of malaria and other parasitic diseases. It works by interfering with the reproduction of the malaria parasite within red blood cells. Quinine has also been used historically as a muscle relaxant and analgesic, but its use for these purposes is now limited due to potential serious side effects. In addition, quinine can be found in some beverages like tonic water, where it is present in very small amounts for flavoring purposes.

Taste threshold is the minimum concentration of a taste substance that can be detected by the taste buds. It is the point at which a person can just discriminate the presence of a specific taste (sweet, salty, sour, bitter, or umami) from plain water or another tastant. The taste threshold can be measured through various methods, such as whole-mouth tastings or using specialized taste strips, and it can vary among individuals due to factors like age, genetics, and exposure to certain chemicals or medications.

The solitary nucleus, also known as the nucleus solitarius, is a collection of neurons located in the medulla oblongata region of the brainstem. It plays a crucial role in the processing and integration of sensory information, particularly taste and visceral afferent fibers from internal organs. The solitary nucleus receives inputs from various cranial nerves, including the glossopharyngeal (cranial nerve IX) and vagus nerves (cranial nerve X), and is involved in reflex responses related to swallowing, vomiting, and cardiovascular regulation.

Sucrose is a type of simple sugar, also known as a carbohydrate. It is a disaccharide, which means that it is made up of two monosaccharides: glucose and fructose. Sucrose occurs naturally in many fruits and vegetables and is often extracted and refined for use as a sweetener in food and beverages.

The chemical formula for sucrose is C12H22O11, and it has a molecular weight of 342.3 g/mol. In its pure form, sucrose is a white, odorless, crystalline solid that is highly soluble in water. It is commonly used as a reference compound for determining the sweetness of other substances, with a standard sucrose solution having a sweetness value of 1.0.

Sucrose is absorbed by the body through the small intestine and metabolized into glucose and fructose, which are then used for energy or stored as glycogen in the liver and muscles. While moderate consumption of sucrose is generally considered safe, excessive intake can contribute to weight gain, tooth decay, and other health problems.

Flavoring agents are substances added to foods, beverages, pharmaceuticals, and sometimes even medical devices to enhance or modify their taste and aroma. They can be natural, derived from plants or animals, or synthetic, created in a laboratory. Flavoring agents do not necessarily provide any nutritional value and are typically used in small quantities.

In a medical context, flavoring agents may be added to medications to improve patient compliance, especially for children or individuals who have difficulty swallowing pills. These agents can help mask the unpleasant taste of certain medicines, making them more palatable and easier to consume. However, it is essential to ensure that the use of flavoring agents does not interfere with the medication's effectiveness or safety.

Chemoreceptor cells are specialized sensory neurons that detect and respond to chemical changes in the internal or external environment. They play a crucial role in maintaining homeostasis within the body by converting chemical signals into electrical impulses, which are then transmitted to the central nervous system for further processing and response.

There are two main types of chemoreceptor cells:

1. Oxygen Chemoreceptors: These cells are located in the carotid bodies near the bifurcation of the common carotid artery and in the aortic bodies close to the aortic arch. They monitor the levels of oxygen, carbon dioxide, and pH in the blood and respond to decreases in oxygen concentration or increases in carbon dioxide and hydrogen ions (indicating acidity) by increasing their firing rate. This signals the brain to increase respiratory rate and depth, thereby restoring normal oxygen levels.

2. Taste Cells: These chemoreceptor cells are found within the taste buds of the tongue and other areas of the oral cavity. They detect specific tastes (salty, sour, sweet, bitter, and umami) by interacting with molecules from food. When a tastant binds to receptors on the surface of a taste cell, it triggers a series of intracellular signaling events that ultimately lead to the generation of an action potential. This information is then relayed to the brain, where it is interpreted as taste sensation.

In summary, chemoreceptor cells are essential for maintaining physiological balance by detecting and responding to chemical stimuli in the body. They play a critical role in regulating vital functions such as respiration and digestion.

Sodium Chloride is defined as the inorganic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. It is commonly known as table salt or halite, and it is used extensively in food seasoning and preservation due to its ability to enhance flavor and inhibit bacterial growth. In medicine, sodium chloride is used as a balanced electrolyte solution for rehydration and as a topical wound irrigant and antiseptic. It is also an essential component of the human body's fluid balance and nerve impulse transmission.

Saccharin is not a medical term, but it is a chemical compound that is widely used as an artificial sweetener. Medically speaking, saccharin is classified as an intense sugar substitute, meaning it is many times sweeter than sucrose (table sugar) but contributes little to no calories when added to food or drink.

Saccharin is often used by people with diabetes or those who are trying to reduce their calorie intake. It has been in use for over a century and has undergone extensive safety testing. The U.S. Food and Drug Administration (FDA) has classified saccharin as generally recognized as safe (GRAS), although it once required a warning label due to concerns about bladder cancer. However, subsequent research has largely dismissed this risk for most people, and the warning label is no longer required.

It's important to note that while saccharin and other artificial sweeteners can be helpful for some individuals, they should not be used as a replacement for a balanced diet and regular exercise. Additionally, excessive consumption of these sugar substitutes may have negative health consequences, such as altering gut bacteria or contributing to metabolic disorders.

Food preferences are personal likes or dislikes towards certain types of food or drinks, which can be influenced by various factors such as cultural background, individual experiences, taste, texture, smell, appearance, and psychological factors. Food preferences can also be shaped by dietary habits, nutritional needs, health conditions, and medication requirements. They play a significant role in shaping an individual's dietary choices and overall eating behavior, which can have implications for their nutritional status, growth, development, and long-term health outcomes.

"Sensilla" is a term used in anatomy and physiology, particularly in insects and other arthropods. It refers to the sensory structures or receptors found on the external surface of these organisms, which are responsible for detecting various environmental stimuli such as touch, taste, smell, temperature, and humidity.

These sensilla are often small, hair-like or peg-like projections that contain one or more sensory cells or neurons. They can be found on different parts of the insect body, including the antennae, legs, mouthparts, and cerci. The structure and function of sensilla vary depending on their location and the type of stimuli they detect.

Overall, sensilla play a crucial role in helping insects and other arthropods navigate and interact with their environment, allowing them to respond to various stimuli and make appropriate behavioral decisions.

Sweetening agents are substances that are added to foods or drinks to give them a sweet taste. They can be natural, like sugar (sucrose), honey, and maple syrup, or artificial, like saccharin, aspartame, and sucralose. Artificial sweeteners are often used by people who want to reduce their calorie intake or control their blood sugar levels. However, it's important to note that some sweetening agents may have potential health concerns when consumed in large amounts.

Sodium glutamate, also known as monosodium glutamate (MSG), is the sodium salt of glutamic acid, which is a naturally occurring amino acid that is widely present in various foods. It is commonly used as a flavor enhancer in the food industry to intensify the savory or umami taste of certain dishes.

Medically speaking, sodium glutamate is generally considered safe for consumption in moderate amounts by the majority of the population. However, some individuals may experience adverse reactions after consuming foods containing MSG, a condition known as "MSG symptom complex." Symptoms can include headache, flushing, sweating, facial pressure or tightness, numbness, tingling or burning in the face, neck and other areas, rapid, fluttering heartbeats (heart palpitations), chest pain, nausea, and weakness.

It is important to note that these symptoms are usually mild and short-term, and not everyone who consumes MSG will experience them. If you suspect that you have an intolerance or sensitivity to MSG, it is best to consult with a healthcare professional for proper evaluation and guidance.

A chemical stimulation in a medical context refers to the process of activating or enhancing physiological or psychological responses in the body using chemical substances. These chemicals can interact with receptors on cells to trigger specific reactions, such as neurotransmitters and hormones that transmit signals within the nervous system and endocrine system.

Examples of chemical stimulation include the use of medications, drugs, or supplements that affect mood, alertness, pain perception, or other bodily functions. For instance, caffeine can chemically stimulate the central nervous system to increase alertness and decrease feelings of fatigue. Similarly, certain painkillers can chemically stimulate opioid receptors in the brain to reduce the perception of pain.

It's important to note that while chemical stimulation can have therapeutic benefits, it can also have adverse effects if used improperly or in excessive amounts. Therefore, it's essential to follow proper dosing instructions and consult with a healthcare provider before using any chemical substances for stimulation purposes.

The term "nervous system physiological processes" refers to the various functional activities and mechanisms that occur within the nervous system, which is responsible for controlling and coordinating bodily functions. These processes include:

1. Electrical impulse transmission: The nervous system transmits electrical signals called action potentials through neurons to transmit information between different parts of the body.
2. Neurotransmitter release and reception: Neurons communicate with each other and with other cells by releasing neurotransmitters, which are chemical messengers that bind to receptors on target cells.
3. Sensory perception: Specialized sensory neurons detect changes in the external environment (e.g., light, sound, temperature, touch) or internal environment (e.g., blood pressure, pH, glucose levels) and transmit this information to the brain for processing.
4. Motor control: The nervous system controls voluntary and involuntary movements by sending signals from the brain to muscles and glands.
5. Homeostasis: The nervous system helps maintain internal homeostasis by regulating vital functions such as heart rate, respiratory rate, body temperature, and fluid balance.
6. Cognition: The nervous system is involved in higher cognitive functions such as learning, memory, attention, perception, and language.
7. Emotional regulation: The nervous system plays a crucial role in emotional processing and regulation through its connections with the limbic system and hypothalamus.
8. Sleep-wake cycle: The nervous system regulates the sleep-wake cycle through the interaction of various neurotransmitters and brain regions.

These physiological processes are essential for normal bodily function and are tightly regulated to ensure optimal performance. Dysfunction in any aspect of the nervous system can lead to a wide range of neurological and psychiatric disorders.

In medical terms, the sense of smell is referred to as olfaction. It is the ability to detect and identify different types of chemicals in the air through the use of the olfactory system. The olfactory system includes the nose, nasal passages, and the olfactory bulbs located in the brain.

When a person inhales air containing volatile substances, these substances bind to specialized receptor cells in the nasal passage called olfactory receptors. These receptors then transmit signals to the olfactory bulbs, which process the information and send it to the brain's limbic system, including the hippocampus and amygdala, as well as to the cortex. The brain interprets these signals and identifies the various scents or smells.

Impairment of the sense of smell can occur due to various reasons such as upper respiratory infections, sinusitis, nasal polyps, head trauma, or neurodegenerative disorders like Parkinson's disease and Alzheimer's disease. Loss of smell can significantly impact a person's quality of life, including their ability to taste food, detect dangers such as smoke or gas leaks, and experience emotions associated with certain smells.

Citric acid is a weak organic acid that is widely found in nature, particularly in citrus fruits such as lemons and oranges. Its chemical formula is C6H8O7, and it exists in a form known as a tribasic acid, which means it can donate three protons in chemical reactions.

In the context of medical definitions, citric acid may be mentioned in relation to various physiological processes, such as its role in the Krebs cycle (also known as the citric acid cycle), which is a key metabolic pathway involved in energy production within cells. Additionally, citric acid may be used in certain medical treatments or therapies, such as in the form of citrate salts to help prevent the formation of kidney stones. It may also be used as a flavoring agent or preservative in various pharmaceutical preparations.

Vagus nerve injuries refer to damages or traumas affecting the vagus nerve, which is the tenth cranial nerve (CN X) in the human body. This nerve plays a crucial role in the autonomic nervous system, regulating essential functions such as heart rate, respiratory rate, and digestion.

Vagus nerve injuries can occur due to various reasons, including trauma during surgical procedures, neck or head injuries, inflammation, compression, or tumors affecting the nerve. Symptoms of vagus nerve injuries may include:

1. Hoarseness or voice changes
2. Difficulty swallowing (dysphagia)
3. Pain in the throat or ear
4. Changes in heart rate and blood pressure
5. Nausea, vomiting, or abdominal pain
6. Shortness of breath or difficulty breathing

The severity and nature of symptoms can vary depending on the location and extent of the injury to the vagus nerve. Treatment for vagus nerve injuries typically involves addressing the underlying cause, such as surgical intervention, physical therapy, or medication to manage pain and inflammation. In some cases, recovery may be incomplete, leading to long-term complications or disabilities.

Sense organs are specialized structures in living organisms that are responsible for receiving and processing various external or internal stimuli, such as light, sound, taste, smell, temperature, and touch. They convert these stimuli into electrical signals that can be interpreted by the nervous system, allowing the organism to interact with and respond to its environment. Examples of sense organs include the eyes, ears, nose, tongue, and skin.

I'm sorry for any confusion, but the "Pleasure-Pain Principle" is not a recognized medical term or concept in the field of medicine or psychology. It may be a misunderstanding or misinterpretation of the "Pleasure Principle," which is a psychological concept introduced by Sigmund Freud. The Pleasure Principle posits that individuals are motivated to seek pleasure and avoid pain, in order to maintain a state of homeostasis or equilibrium. However, it's important to note that this concept is not without its criticisms and controversies within the field of psychology.

Hydrochloric acid, also known as muriatic acid, is not a substance that is typically found within the human body. It is a strong mineral acid with the chemical formula HCl. In a medical context, it might be mentioned in relation to gastric acid, which helps digest food in the stomach. Gastric acid is composed of hydrochloric acid, potassium chloride and sodium chloride dissolved in water. The pH of hydrochloric acid is very low (1-2) due to its high concentration of H+ ions, making it a strong acid. However, it's important to note that the term 'hydrochloric acid' does not directly refer to a component of human bodily fluids or tissues.

Feeding behavior refers to the various actions and mechanisms involved in the intake of food and nutrition for the purpose of sustaining life, growth, and health. This complex process encompasses a coordinated series of activities, including:

1. Food selection: The identification, pursuit, and acquisition of appropriate food sources based on sensory cues (smell, taste, appearance) and individual preferences.
2. Preparation: The manipulation and processing of food to make it suitable for consumption, such as chewing, grinding, or chopping.
3. Ingestion: The act of transferring food from the oral cavity into the digestive system through swallowing.
4. Digestion: The mechanical and chemical breakdown of food within the gastrointestinal tract to facilitate nutrient absorption and eliminate waste products.
5. Assimilation: The uptake and utilization of absorbed nutrients by cells and tissues for energy production, growth, repair, and maintenance.
6. Elimination: The removal of undigested material and waste products from the body through defecation.

Feeding behavior is regulated by a complex interplay between neural, hormonal, and psychological factors that help maintain energy balance and ensure adequate nutrient intake. Disruptions in feeding behavior can lead to various medical conditions, such as malnutrition, obesity, eating disorders, and gastrointestinal motility disorders.

The pons is a part of the brainstem that lies between the medulla oblongata and the midbrain. Its name comes from the Latin word "ponte" which means "bridge," as it serves to connect these two regions of the brainstem. The pons contains several important structures, including nerve fibers that carry signals between the cerebellum (the part of the brain responsible for coordinating muscle movements) and the rest of the nervous system. It also contains nuclei (clusters of neurons) that help regulate various functions such as respiration, sleep, and facial movements.

Olfactory perception refers to the ability to perceive and recognize odors or smells, which is mediated by olfactory receptor neurons located in the nasal cavity. These neurons detect and transmit information about chemical compounds present in the inhaled air to the brain, specifically to the primary olfactory cortex, where the perception of smell is processed and integrated with other sensory inputs. Olfactory perception plays a crucial role in various aspects of human behavior, including food selection, safety, and emotional responses.

Ageusia is a medical term that refers to the complete loss of taste. It can affect a person's ability to detect sweet, salty, sour, bitter, and savory flavors. Ageusia can be caused by various factors such as damage to the nerves responsible for transmitting taste signals to the brain, exposure to certain chemicals or radiation therapy, and some medical conditions like diabetes, hypertension, and upper respiratory infections. In some cases, ageusia may be temporary, while in others, it can be permanent. It is important to consult a healthcare professional if experiencing a loss of taste, as it could be a sign of an underlying health issue.

Sensory receptor cells are specialized structures that convert physical stimuli from our environment into electrical signals, which are then transmitted to the brain for interpretation. These receptors can be found in various tissues throughout the body and are responsible for detecting sensations such as touch, pressure, temperature, taste, and smell. They can be classified into two main types: exteroceptors, which respond to stimuli from the external environment, and interoceptors, which react to internal conditions within the body. Examples of sensory receptor cells include hair cells in the inner ear, photoreceptors in the eye, and taste buds on the tongue.

Afferent pathways, also known as sensory pathways, refer to the neural connections that transmit sensory information from the peripheral nervous system to the central nervous system (CNS), specifically to the brain and spinal cord. These pathways are responsible for carrying various types of sensory information, such as touch, temperature, pain, pressure, vibration, hearing, vision, and taste, to the CNS for processing and interpretation.

The afferent pathways begin with sensory receptors located throughout the body, which detect changes in the environment and convert them into electrical signals. These signals are then transmitted via afferent neurons, also known as sensory neurons, to the spinal cord or brainstem. Within the CNS, the information is further processed and integrated with other neural inputs before being relayed to higher cognitive centers for conscious awareness and response.

Understanding the anatomy and physiology of afferent pathways is essential for diagnosing and treating various neurological conditions that affect sensory function, such as neuropathies, spinal cord injuries, and brain disorders.

Avoidance learning is a type of conditioning in which an individual learns to act in a certain way to avoid experiencing an unpleasant or aversive stimulus. It is a form of learning that occurs when an organism changes its behavior to avoid a negative outcome or situation. This can be seen in both animals and humans, and it is often studied in the field of psychology and neuroscience.

In avoidance learning, the individual learns to associate a particular cue or stimulus with the unpleasant experience. Over time, they learn to perform an action to escape or avoid the cue, thereby preventing the negative outcome from occurring. For example, if a rat receives an electric shock every time it hears a certain tone, it may eventually learn to press a lever to turn off the tone and avoid the shock.

Avoidance learning can be adaptive in some situations, as it allows individuals to avoid dangerous or harmful stimuli. However, it can also become maladaptive if it leads to excessive fear or anxiety, or if it interferes with an individual's ability to function in daily life. For example, a person who has been attacked may develop a phobia of public places and avoid them altogether, even though this limits their ability to engage in social activities and live a normal life.

In summary, avoidance learning is a type of conditioning in which an individual learns to act in a certain way to avoid experiencing an unpleasant or aversive stimulus. It can be adaptive in some situations but can also become maladaptive if it leads to excessive fear or anxiety or interferes with daily functioning.

Afferent neurons, also known as sensory neurons, are a type of nerve cell that conducts impulses or signals from peripheral receptors towards the central nervous system (CNS), which includes the brain and spinal cord. These neurons are responsible for transmitting sensory information such as touch, temperature, pain, sound, and light to the CNS for processing and interpretation. Afferent neurons have specialized receptor endings that detect changes in the environment and convert them into electrical signals, which are then transmitted to the CNS via synapses with other neurons. Once the signals reach the CNS, they are processed and integrated with other information to produce a response or reaction to the stimulus.

To the best of my knowledge, there is no medical definition for "courtship" as it is a term that is more commonly used in social and cultural contexts rather than in the field of medicine. Courtship generally refers to the period of time during which two people engage in various social activities to get to know each other and determine whether they are compatible before deciding to start a romantic relationship or get married.

However, it's worth noting that some aspects of courtship, such as dating and forming intimate relationships, can have implications for mental and physical health. For example, having positive and satisfying relationships is associated with better mental and physical health outcomes, while being in abusive or unhealthy relationships can negatively impact one's well-being.

The lingual nerve is a branch of the mandibular division of the trigeminal nerve (cranial nerve V). It provides general sensory innervation to the anterior two-thirds of the tongue, including taste sensation from the same region. It also supplies sensory innervation to the floor of the mouth and the lingual gingiva (gum tissue). The lingual nerve is closely associated with the submandibular and sublingual salivary glands and their ducts.

'Drosophila proteins' refer to the proteins that are expressed in the fruit fly, Drosophila melanogaster. This organism is a widely used model system in genetics, developmental biology, and molecular biology research. The study of Drosophila proteins has contributed significantly to our understanding of various biological processes, including gene regulation, cell signaling, development, and aging.

Some examples of well-studied Drosophila proteins include:

1. HSP70 (Heat Shock Protein 70): A chaperone protein involved in protein folding and protection from stress conditions.
2. TUBULIN: A structural protein that forms microtubules, important for cell division and intracellular transport.
3. ACTIN: A cytoskeletal protein involved in muscle contraction, cell motility, and maintenance of cell shape.
4. BETA-GALACTOSIDASE (LACZ): A reporter protein often used to monitor gene expression patterns in transgenic flies.
5. ENDOGLIN: A protein involved in the development of blood vessels during embryogenesis.
6. P53: A tumor suppressor protein that plays a crucial role in preventing cancer by regulating cell growth and division.
7. JUN-KINASE (JNK): A signaling protein involved in stress response, apoptosis, and developmental processes.
8. DECAPENTAPLEGIC (DPP): A member of the TGF-β (Transforming Growth Factor Beta) superfamily, playing essential roles in embryonic development and tissue homeostasis.

These proteins are often studied using various techniques such as biochemistry, genetics, molecular biology, and structural biology to understand their functions, interactions, and regulation within the cell.

Neurons, also known as nerve cells or neurocytes, are specialized cells that constitute the basic unit of the nervous system. They are responsible for receiving, processing, and transmitting information and signals within the body. Neurons have three main parts: the dendrites, the cell body (soma), and the axon. The dendrites receive signals from other neurons or sensory receptors, while the axon transmits these signals to other neurons, muscles, or glands. The junction between two neurons is called a synapse, where neurotransmitters are released to transmit the signal across the gap (synaptic cleft) to the next neuron. Neurons vary in size, shape, and structure depending on their function and location within the nervous system.

Lithium Chloride (LiCl) is not typically defined in a medical context as it is not a medication or a clinical condition. However, it can be defined chemically as an inorganic compound consisting of lithium and chlorine. Its chemical formula is LiCl, and it is commonly used in laboratory settings for various purposes such as a drying agent or a component in certain chemical reactions.

It's worth noting that while lithium salts like lithium carbonate (Li2CO3) are used medically to treat bipolar disorder, lithium chloride is not used for this purpose due to its higher toxicity compared to other lithium salts.

Sensory ganglia are clusters of nerve cell bodies located outside the central nervous system (the brain and spinal cord). They are primarily associated with sensory neurons, which are responsible for transmitting sensory information from various parts of the body to the central nervous system.

In humans, there are two main types of sensory ganglia: dorsal root ganglia and cranial nerve ganglia. Dorsal root ganglia are located along the spinal cord and contain the cell bodies of sensory neurons that innervate the skin, muscles, joints, and other tissues of the body. These neurons transmit information about touch, temperature, pain, and proprioception (the sense of the position and movement of the body).

Cranial nerve ganglia are associated with the cranial nerves, which are responsible for transmitting sensory information from the head and neck to the brain. For example, the trigeminal ganglion is a cranial nerve ganglion that contains the cell bodies of neurons that transmit sensory information from the face, mouth, and other structures of the head.

Overall, sensory ganglia play a critical role in our ability to perceive and interact with the world around us by transmitting important sensory information to the brain for processing.

Odorant receptors are a type of G protein-coupled receptor (GPCR) that are primarily found in the cilia of olfactory sensory neurons in the nose. These receptors are responsible for detecting and transmitting information about odorants, or volatile molecules that we perceive as smells.

Each odorant receptor can bind to a specific set of odorant molecules, and when an odorant binds to its corresponding receptor, it triggers a signaling cascade that ultimately leads to the generation of an electrical signal in the olfactory sensory neuron. This signal is then transmitted to the brain, where it is processed and interpreted as a particular smell.

There are thought to be around 400 different types of odorant receptors in humans, each with its own unique binding profile. The combinatorial coding of these receptors allows for the detection and discrimination of a vast array of different smells, from sweet to sour, floral to fruity, and everything in between.

Overall, the ability to detect and respond to odorants is critical for many important functions, including the identification of food, mates, and potential dangers in the environment.

'Animal behavior' refers to the actions or responses of animals to various stimuli, including their interactions with the environment and other individuals. It is the study of the actions of animals, whether they are instinctual, learned, or a combination of both. Animal behavior includes communication, mating, foraging, predator avoidance, and social organization, among other things. The scientific study of animal behavior is called ethology. This field seeks to understand the evolutionary basis for behaviors as well as their physiological and psychological mechanisms.

Olfaction disorders, also known as smell disorders, refer to conditions that affect the ability to detect or interpret odors. These disorders can be categorized into two main types:

1. Anosmia: This is a complete loss of the sense of smell. It can be caused by various factors such as nasal polyps, sinus infections, head injuries, and degenerative diseases like Alzheimer's and Parkinson's.
2. Hyposmia: This is a reduced ability to detect odors. Like anosmia, it can also be caused by similar factors including aging and exposure to certain chemicals.

Other olfaction disorders include parosmia, which is a distortion of smell where individuals may perceive a smell as being different from its original scent, and phantosmia, which is the perception of a smell that isn't actually present.

I'm sorry for any confusion, but "Ulex" is not a medical term. It is actually the name of a genus of spiny shrubs commonly known as gorse or furze, which are native to western Europe. The misconception might arise from the fact that some plants, like Ulex, contain certain chemical compounds that can have medicinal properties and thus might be mentioned in medical contexts. However, "Ulex" itself is not a medical term.

Cell surface receptors, also known as membrane receptors, are proteins located on the cell membrane that bind to specific molecules outside the cell, known as ligands. These receptors play a crucial role in signal transduction, which is the process of converting an extracellular signal into an intracellular response.

Cell surface receptors can be classified into several categories based on their structure and mechanism of action, including:

1. Ion channel receptors: These receptors contain a pore that opens to allow ions to flow across the cell membrane when they bind to their ligands. This ion flux can directly activate or inhibit various cellular processes.
2. G protein-coupled receptors (GPCRs): These receptors consist of seven transmembrane domains and are associated with heterotrimeric G proteins that modulate intracellular signaling pathways upon ligand binding.
3. Enzyme-linked receptors: These receptors possess an intrinsic enzymatic activity or are linked to an enzyme, which becomes activated when the receptor binds to its ligand. This activation can lead to the initiation of various signaling cascades within the cell.
4. Receptor tyrosine kinases (RTKs): These receptors contain intracellular tyrosine kinase domains that become activated upon ligand binding, leading to the phosphorylation and activation of downstream signaling molecules.
5. Integrins: These receptors are transmembrane proteins that mediate cell-cell or cell-matrix interactions by binding to extracellular matrix proteins or counter-receptors on adjacent cells. They play essential roles in cell adhesion, migration, and survival.

Cell surface receptors are involved in various physiological processes, including neurotransmission, hormone signaling, immune response, and cell growth and differentiation. Dysregulation of these receptors can contribute to the development of numerous diseases, such as cancer, diabetes, and neurological disorders.

'Drosophila melanogaster' is the scientific name for a species of fruit fly that is commonly used as a model organism in various fields of biological research, including genetics, developmental biology, and evolutionary biology. Its small size, short generation time, large number of offspring, and ease of cultivation make it an ideal subject for laboratory studies. The fruit fly's genome has been fully sequenced, and many of its genes have counterparts in the human genome, which facilitates the understanding of genetic mechanisms and their role in human health and disease.

Here is a brief medical definition:

Drosophila melanogaster (droh-suh-fih-luh meh-lon-guh-ster): A species of fruit fly used extensively as a model organism in genetic, developmental, and evolutionary research. Its genome has been sequenced, revealing many genes with human counterparts, making it valuable for understanding genetic mechanisms and their role in human health and disease.

The cerebral cortex is the outermost layer of the brain, characterized by its intricate folded structure and wrinkled appearance. It is a region of great importance as it plays a key role in higher cognitive functions such as perception, consciousness, thought, memory, language, and attention. The cerebral cortex is divided into two hemispheres, each containing four lobes: the frontal, parietal, temporal, and occipital lobes. These areas are responsible for different functions, with some regions specializing in sensory processing while others are involved in motor control or associative functions. The cerebral cortex is composed of gray matter, which contains neuronal cell bodies, and is covered by a layer of white matter that consists mainly of myelinated nerve fibers.

In medical terms, "hunger" is not specifically defined as a clinical condition. However, it generally refers to the physiological need or desire for food and calories, driven by mechanisms in the brain and body that regulate energy balance. This sensation often arises when the body's energy stores are depleted, or when there has been a prolonged period without food intake.

Hunger is primarily mediated by hormones such as ghrelin, which stimulates appetite, and leptin, which signals satiety. The hypothalamus in the brain plays a crucial role in integrating these hormonal signals to regulate hunger and energy balance. Additionally, other factors like sleep deprivation, stress, and certain medical conditions can also influence feelings of hunger.

The facial nerve, also known as the seventh cranial nerve (CN VII), is a mixed nerve that carries both sensory and motor fibers. Its functions include controlling the muscles involved in facial expressions, taste sensation from the anterior two-thirds of the tongue, and secretomotor function to the lacrimal and salivary glands.

The facial nerve originates from the brainstem and exits the skull through the internal acoustic meatus. It then passes through the facial canal in the temporal bone before branching out to innervate various structures of the face. The main branches of the facial nerve include:

1. Temporal branch: Innervates the frontalis, corrugator supercilii, and orbicularis oculi muscles responsible for eyebrow movements and eyelid closure.
2. Zygomatic branch: Supplies the muscles that elevate the upper lip and wrinkle the nose.
3. Buccal branch: Innervates the muscles of the cheek and lips, allowing for facial expressions such as smiling and puckering.
4. Mandibular branch: Controls the muscles responsible for lower lip movement and depressing the angle of the mouth.
5. Cervical branch: Innervates the platysma muscle in the neck, which helps to depress the lower jaw and wrinkle the skin of the neck.

Damage to the facial nerve can result in various symptoms, such as facial weakness or paralysis, loss of taste sensation, and dry eyes or mouth due to impaired secretion.

Drinking behavior refers to the patterns and habits related to alcohol consumption. This can include the frequency, quantity, and context in which an individual chooses to drink alcohol. Drinking behaviors can vary widely among individuals and can be influenced by a variety of factors, including cultural norms, personal beliefs, mental health status, and genetic predisposition.

Problematic drinking behaviors can include heavy drinking, binge drinking, and alcohol use disorder (AUD), which is characterized by a pattern of alcohol use that involves problems controlling intake, being preoccupied with alcohol, continuing to use alcohol even when it causes problems, having to drink more to get the same effect, or having withdrawal symptoms when rapidly decreasing or stopping alcohol.

It's important to note that drinking behaviors can have significant impacts on an individual's health and well-being, as well as their relationships, work, and other aspects of their life. If you are concerned about your own drinking behavior or that of someone else, it is recommended to seek professional help from a healthcare provider or addiction specialist.

"Rana catesbeiana" is the scientific name for the American bullfrog, which is not a medical term or concept. It belongs to the animal kingdom, specifically in the order Anura and family Ranidae. The American bullfrog is native to North America and is known for its large size and distinctive loud call.

However, if you are looking for a medical definition, I apologize for any confusion. Please provide more context or specify the term you would like me to define.

Sodium acetate is an ionic compound with the formula NaC2H3O2. It is formed by the combination of sodium ions (Na+) and acetate ions (C2H3O2-). Sodium acetate is a white, crystalline solid that is highly soluble in water. It is commonly used as a buffer in laboratory settings to help maintain a stable pH level in solutions.

In the body, sodium acetate can be produced as a byproduct of metabolism and is also found in some foods and medications. It is quickly converted to bicarbonate in the body, which helps to regulate the acid-base balance and maintain a normal pH level in the blood. Sodium acetate is sometimes used as a source of sodium and acetate ions in intravenous (IV) fluids to help treat dehydration or metabolic acidosis, a condition in which the body has too much acid.

It's important to note that while sodium acetate is generally considered safe when used as directed, it can cause side effects if taken in large amounts or in combination with certain medications. It is always best to consult with a healthcare provider before using any new medication or supplement.

Electrophysiology is a branch of medicine that deals with the electrical activities of the body, particularly the heart. In a medical context, electrophysiology studies (EPS) are performed to assess abnormal heart rhythms (arrhythmias) and to evaluate the effectiveness of certain treatments, such as medication or pacemakers.

During an EPS, electrode catheters are inserted into the heart through blood vessels in the groin or neck. These catheters can record the electrical activity of the heart and stimulate it to help identify the source of the arrhythmia. The information gathered during the study can help doctors determine the best course of treatment for each patient.

In addition to cardiac electrophysiology, there are also other subspecialties within electrophysiology, such as neuromuscular electrophysiology, which deals with the electrical activity of the nervous system and muscles.

The palate is the roof of the mouth in humans and other mammals, separating the oral cavity from the nasal cavity. It consists of two portions: the anterior hard palate, which is composed of bone, and the posterior soft palate, which is composed of muscle and connective tissue. The palate plays a crucial role in speech, swallowing, and breathing, as it helps to direct food and air to their appropriate locations during these activities.

The soft palate, also known as the velum, is the rear portion of the roof of the mouth that is made up of muscle and mucous membrane. It extends from the hard palate (the bony front part of the roof of the mouth) to the uvula, which is the small piece of tissue that hangs down at the back of the throat.

The soft palate plays a crucial role in speech, swallowing, and breathing. During swallowing, it moves upward and backward to block off the nasal cavity, preventing food and liquids from entering the nose. In speech, it helps to direct the flow of air from the mouth into the nose, which is necessary for producing certain sounds.

Anatomically, the soft palate consists of several muscles that allow it to change shape and move. These muscles include the tensor veli palatini, levator veli palatini, musculus uvulae, palatopharyngeus, and palatoglossus. The soft palate also contains a rich supply of blood vessels and nerves that provide sensation and help regulate its function.

Sprague-Dawley rats are a strain of albino laboratory rats that are widely used in scientific research. They were first developed by researchers H.H. Sprague and R.C. Dawley in the early 20th century, and have since become one of the most commonly used rat strains in biomedical research due to their relatively large size, ease of handling, and consistent genetic background.

Sprague-Dawley rats are outbred, which means that they are genetically diverse and do not suffer from the same limitations as inbred strains, which can have reduced fertility and increased susceptibility to certain diseases. They are also characterized by their docile nature and low levels of aggression, making them easier to handle and study than some other rat strains.

These rats are used in a wide variety of research areas, including toxicology, pharmacology, nutrition, cancer, and behavioral studies. Because they are genetically diverse, Sprague-Dawley rats can be used to model a range of human diseases and conditions, making them an important tool in the development of new drugs and therapies.

Transducin is a G protein found in the rod cells of the retina and plays a crucial role in the visual signal transduction pathway. It is responsible for converting the light-induced isomerization of rhodopsin into a biochemical signal, which ultimately leads to the activation of downstream effectors and the generation of a neural response.

Transducin has three subunits: alpha (Tα), beta (Tβ), and gamma (Tγ). When light activates rhodopsin, it interacts with the Tα subunit, causing it to exchange GDP for GTP and dissociate from the Tβγ complex. The activated Tα then interacts with a downstream effector called phosphodiesterase (PDE), which leads to the hydrolysis of cGMP and the closure of cGMP-gated ion channels in the plasma membrane. This results in the hyperpolarization of the rod cell, which is the initial step in the visual signal transduction pathway.

Overall, transducin is a key player in the conversion of light energy into neural signals, allowing us to see and perceive our visual world.

Nerve fibers are specialized structures that constitute the long, slender processes (axons) of neurons (nerve cells). They are responsible for conducting electrical impulses, known as action potentials, away from the cell body and transmitting them to other neurons or effector organs such as muscles and glands. Nerve fibers are often surrounded by supportive cells called glial cells and are grouped together to form nerve bundles or nerves. These fibers can be myelinated (covered with a fatty insulating sheath called myelin) or unmyelinated, which influences the speed of impulse transmission.

An action potential is a brief electrical signal that travels along the membrane of a nerve cell (neuron) or muscle cell. It is initiated by a rapid, localized change in the permeability of the cell membrane to specific ions, such as sodium and potassium, resulting in a rapid influx of sodium ions and a subsequent efflux of potassium ions. This ion movement causes a brief reversal of the electrical potential across the membrane, which is known as depolarization. The action potential then propagates along the cell membrane as a wave, allowing the electrical signal to be transmitted over long distances within the body. Action potentials play a crucial role in the communication and functioning of the nervous system and muscle tissue.

The brainstem is the lower part of the brain that connects to the spinal cord. It consists of the midbrain, pons, and medulla oblongata. The brainstem controls many vital functions such as heart rate, breathing, and blood pressure. It also serves as a relay center for sensory and motor information between the cerebral cortex and the rest of the body. Additionally, several cranial nerves originate from the brainstem, including those that control eye movements, facial movements, and hearing.

The amygdala is an almond-shaped group of nuclei located deep within the temporal lobe of the brain, specifically in the anterior portion of the temporal lobes and near the hippocampus. It forms a key component of the limbic system and plays a crucial role in processing emotions, particularly fear and anxiety. The amygdala is involved in the integration of sensory information with emotional responses, memory formation, and decision-making processes.

In response to emotionally charged stimuli, the amygdala can modulate various physiological functions, such as heart rate, blood pressure, and stress hormone release, via its connections to the hypothalamus and brainstem. Additionally, it contributes to social behaviors, including recognizing emotional facial expressions and responding appropriately to social cues. Dysfunctions in amygdala function have been implicated in several psychiatric and neurological conditions, such as anxiety disorders, depression, post-traumatic stress disorder (PTSD), and autism spectrum disorder (ASD).

In the context of medicine, particularly in behavioral neuroscience and psychology, "reward" is not typically used as a definitive medical term. However, it generally refers to a positive outcome or incentive that reinforces certain behaviors, making them more likely to be repeated in the future. This can involve various stimuli such as food, water, sexual activity, social interaction, or drug use, among others.

In the brain, rewards are associated with the activation of the reward system, primarily the mesolimbic dopamine pathway, which includes the ventral tegmental area (VTA) and the nucleus accumbens (NAcc). The release of dopamine in these areas is thought to reinforce and motivate behavior linked to rewards.

It's important to note that while "reward" has a specific meaning in this context, it is not a formal medical diagnosis or condition. Instead, it is a concept used to understand the neural and psychological mechanisms underlying motivation, learning, and addiction.

Genetically modified animals (GMAs) are those whose genetic makeup has been altered using biotechnological techniques. This is typically done by introducing one or more genes from another species into the animal's genome, resulting in a new trait or characteristic that does not naturally occur in that species. The introduced gene is often referred to as a transgene.

The process of creating GMAs involves several steps:

1. Isolation: The desired gene is isolated from the DNA of another organism.
2. Transfer: The isolated gene is transferred into the target animal's cells, usually using a vector such as a virus or bacterium.
3. Integration: The transgene integrates into the animal's chromosome, becoming a permanent part of its genetic makeup.
4. Selection: The modified cells are allowed to multiply, and those that contain the transgene are selected for further growth and development.
5. Breeding: The genetically modified individuals are bred to produce offspring that carry the desired trait.

GMAs have various applications in research, agriculture, and medicine. In research, they can serve as models for studying human diseases or testing new therapies. In agriculture, GMAs can be developed to exhibit enhanced growth rates, improved disease resistance, or increased nutritional value. In medicine, GMAs may be used to produce pharmaceuticals or other therapeutic agents within their bodies.

Examples of genetically modified animals include mice with added genes for specific proteins that make them useful models for studying human diseases, goats that produce a human protein in their milk to treat hemophilia, and pigs with enhanced resistance to certain viruses that could potentially be used as organ donors for humans.

It is important to note that the use of genetically modified animals raises ethical concerns related to animal welfare, environmental impact, and potential risks to human health. These issues must be carefully considered and addressed when developing and implementing GMA technologies.

Amiloride is a medication that belongs to a class of drugs called potassium-sparing diuretics. It works by preventing the reabsorption of salt and water in the kidneys, which helps to increase urine output and decrease fluid buildup in the body. At the same time, amiloride also helps to preserve the level of potassium in the body, which is why it is known as a potassium-sparing diuretic.

Amiloride is commonly used to treat high blood pressure, heart failure, and edema (fluid buildup) in the body. It is available in tablet form and is typically taken once or twice a day, with or without food. Common side effects of amiloride include headache, dizziness, and stomach upset.

It's important to note that amiloride can interact with other medications, including some over-the-counter products, so it's essential to inform your healthcare provider of all the medications you are taking before starting amiloride therapy. Additionally, regular monitoring of blood pressure, kidney function, and electrolyte levels is necessary while taking this medication.

G-protein-coupled receptors (GPCRs) are a family of membrane receptors that play an essential role in cellular signaling and communication. These receptors possess seven transmembrane domains, forming a structure that spans the lipid bilayer of the cell membrane. They are called "G-protein-coupled" because they interact with heterotrimeric G proteins upon activation, which in turn modulate various downstream signaling pathways.

When an extracellular ligand binds to a GPCR, it causes a conformational change in the receptor's structure, leading to the exchange of guanosine diphosphate (GDP) for guanosine triphosphate (GTP) on the associated G protein's α subunit. This exchange triggers the dissociation of the G protein into its α and βγ subunits, which then interact with various effector proteins to elicit cellular responses.

There are four main families of GPCRs, classified based on their sequence similarities and downstream signaling pathways:

1. Gq-coupled receptors: These receptors activate phospholipase C (PLC), which leads to the production of inositol trisphosphate (IP3) and diacylglycerol (DAG). IP3 induces calcium release from intracellular stores, while DAG activates protein kinase C (PKC).
2. Gs-coupled receptors: These receptors activate adenylyl cyclase, which increases the production of cyclic adenosine monophosphate (cAMP) and subsequently activates protein kinase A (PKA).
3. Gi/o-coupled receptors: These receptors inhibit adenylyl cyclase, reducing cAMP levels and modulating PKA activity. Additionally, they can activate ion channels or regulate other signaling pathways through the βγ subunits.
4. G12/13-coupled receptors: These receptors primarily activate RhoGEFs, which in turn activate RhoA and modulate cytoskeletal organization and cellular motility.

GPCRs are involved in various physiological processes, including neurotransmission, hormone signaling, immune response, and sensory perception. Dysregulation of GPCR function has been implicated in numerous diseases, making them attractive targets for drug development.

The somatosensory cortex is a part of the brain located in the postcentral gyrus of the parietal lobe, which is responsible for processing sensory information from the body. It receives and integrates tactile, proprioceptive, and thermoception inputs from the skin, muscles, joints, and internal organs, allowing us to perceive and interpret touch, pressure, pain, temperature, vibration, position, and movement of our body parts. The somatosensory cortex is organized in a map-like manner, known as the sensory homunculus, where each body part is represented according to its relative sensitivity and density of innervation. This organization allows for precise localization and discrimination of tactile stimuli across the body surface.

I believe you are asking for a medical explanation or definition of "candy," which is not a term typically used in the medical field. However, I can provide some context regarding how it may be discussed in a medical setting.

Candy, also known as sweets or confectionery, generally refers to sugary snacks and treats. In a medical context, excessive consumption of candy can contribute to dental caries (cavities), obesity, type 2 diabetes, and other health issues related to poor nutrition and high sugar intake.

Healthcare professionals may advise patients, particularly children, to limit their candy consumption due to these potential health risks. Additionally, candies that contain ingredients like nuts or allergens can pose a risk for individuals with specific food allergies.

Pheromones are chemical signals that one organism releases into the environment that can affect the behavior or physiology of other organisms of the same species. They are primarily used for communication in animals, including insects and mammals. In humans, the existence and role of pheromones are still a subject of ongoing research and debate.

In a medical context, pheromones may be discussed in relation to certain medical conditions or treatments that involve olfactory (smell) stimuli, such as some forms of aromatherapy. However, it's important to note that the use of pheromones as a medical treatment is not widely accepted and more research is needed to establish their effectiveness and safety.

I'm sorry for any confusion, but "Goldfish" is not a term used in medical definitions. Goldfish are small domesticated fish that are often kept as pets. They belong to the family Cyprinidae and the genus Carassius. The most common species of goldfish is Carassius auratus. If you have any questions about goldfish or their care, I might be able to help with some general information, but for specific medical concerns, it would be best to consult a veterinarian.

Neural pathways, also known as nerve tracts or fasciculi, refer to the highly organized and specialized routes through which nerve impulses travel within the nervous system. These pathways are formed by groups of neurons (nerve cells) that are connected in a series, creating a continuous communication network for electrical signals to transmit information between different regions of the brain, spinal cord, and peripheral nerves.

Neural pathways can be classified into two main types: sensory (afferent) and motor (efferent). Sensory neural pathways carry sensory information from various receptors in the body (such as those for touch, temperature, pain, and vision) to the brain for processing. Motor neural pathways, on the other hand, transmit signals from the brain to the muscles and glands, controlling movements and other effector functions.

The formation of these neural pathways is crucial for normal nervous system function, as it enables efficient communication between different parts of the body and allows for complex behaviors, cognitive processes, and adaptive responses to internal and external stimuli.

Denervation is a medical term that refers to the loss or removal of nerve supply to an organ or body part. This can occur as a result of surgical intervention, injury, or disease processes that damage the nerves leading to the affected area. The consequences of denervation depend on the specific organ or tissue involved, but generally, it can lead to changes in function, sensation, and muscle tone. For example, denervation of a skeletal muscle can cause weakness, atrophy, and altered reflexes. Similarly, denervation of an organ such as the heart can lead to abnormalities in heart rate and rhythm. In some cases, denervation may be intentional, such as during surgical procedures aimed at treating chronic pain or spasticity.

Appetite is the desire to eat or drink something, which is often driven by feelings of hunger or thirst. It is a complex process that involves both physiological and psychological factors. Physiologically, appetite is influenced by the body's need for energy and nutrients, as well as various hormones and neurotransmitters that regulate hunger and satiety signals in the brain. Psychologically, appetite can be affected by emotions, mood, stress levels, and social factors such as the sight or smell of food.

In medical terms, a loss of appetite is often referred to as anorexia, which can be caused by various factors such as illness, medication, infection, or psychological conditions like depression. On the other hand, an excessive or abnormal appetite is known as polyphagia and can be a symptom of certain medical conditions such as diabetes or hyperthyroidism.

It's important to note that while "anorexia" is a medical term used to describe loss of appetite, it should not be confused with the eating disorder anorexia nervosa, which is a serious mental health condition characterized by restrictive eating, distorted body image, and fear of gaining weight.

Visceral afferents are specialized nerve fibers that carry sensory information from the internal organs (viscera) to the central nervous system. These afferent neurons detect and transmit information about various visceral stimuli, such as pain, temperature, touch, pressure, chemical changes, and the state of organ distension or fullness. The information they relay helps regulate physiological functions, including digestion, respiration, and cardiovascular activity, and contributes to the perception of bodily sensations and visceral pain. Visceral afferents are an essential component of the autonomic nervous system and have their cell bodies located in the dorsal root ganglia or nodose ganglia.

Dietary sucrose is a type of sugar that is commonly found in the human diet. It is a disaccharide, meaning it is composed of two monosaccharides: glucose and fructose. Sucrose is naturally occurring in many fruits and vegetables, but it is also added to a wide variety of processed foods and beverages as a sweetener.

In the body, sucrose is broken down into its component monosaccharides during digestion, which are then absorbed into the bloodstream and used for energy. While small amounts of sucrose can be part of a healthy diet, consuming large amounts of added sugars, including sucrose, has been linked to a variety of negative health outcomes, such as obesity, type 2 diabetes, and heart disease. Therefore, it is recommended that people limit their intake of added sugars and focus on getting their sugars from whole foods, such as fruits and vegetables.

A larva is a distinct stage in the life cycle of various insects, mites, and other arthropods during which they undergo significant metamorphosis before becoming adults. In a medical context, larvae are known for their role in certain parasitic infections. Specifically, some helminth (parasitic worm) species use larval forms to infect human hosts. These invasions may lead to conditions such as cutaneous larva migrans, visceral larva migrans, or gnathostomiasis, depending on the specific parasite involved and the location of the infection within the body.

The larval stage is characterized by its markedly different morphology and behavior compared to the adult form. Larvae often have a distinct appearance, featuring unsegmented bodies, simple sense organs, and undeveloped digestive systems. They are typically adapted for a specific mode of life, such as free-living or parasitic existence, and rely on external sources of nutrition for their development.

In the context of helminth infections, larvae may be transmitted to humans through various routes, including ingestion of contaminated food or water, direct skin contact with infective stages, or transmission via an intermediate host (such as a vector). Once inside the human body, these parasitic larvae can cause tissue damage and provoke immune responses, leading to the clinical manifestations of disease.

It is essential to distinguish between the medical definition of 'larva' and its broader usage in biology and zoology. In those fields, 'larva' refers to any juvenile form that undergoes metamorphosis before reaching adulthood, regardless of whether it is parasitic or not.

Arthropod antennae are the primary sensory organs found in arthropods, which include insects, crustaceans, arachnids, and myriapods. These paired appendages are usually located on the head or nearest segment to the head and are responsible for detecting various stimuli from the environment such as touch, taste, smell, temperature, humidity, vibration, and air motion.

The structure of arthropod antennae varies among different groups but generally consists of one or more segments called flagellum or funicle that may be further divided into subsegments called annuli. The number and arrangement of these segments are often used to classify and identify specific taxa.

Insect antennae, for example, typically have a distinct shape and can be thread-like, feathery, or clubbed depending on the species. They contain various sensory receptors such as olfactory neurons that detect odor molecules, mechanoreceptors that respond to touch or movement, and thermoreceptors that sense temperature changes.

Overall, arthropod antennae play a crucial role in enabling these organisms to navigate their environment, find food, avoid predators, and communicate with conspecifics.

Lobeline is not a medical term per se, but it is a pharmacological substance with some potential medical applications. Lobeline is an alkaloid compound that can be found in certain plants, including the Indian tobacco plant (Lobelia inflata). It has been used in some over-the-counter and prescription medications as a smoking cessation aid due to its ability to stimulate nicotinic acetylcholine receptors in the brain, which may help reduce cravings for nicotine.

However, it's important to note that the effectiveness of lobeline as a smoking cessation aid is still a matter of debate and further research is needed to fully understand its potential benefits and risks.

"Long-Evans" is a strain of laboratory rats commonly used in scientific research. They are named after their developers, the scientists Long and Evans. This strain is albino, with a brownish-black hood over their eyes and ears, and they have an agouti (salt-and-pepper) color on their backs. They are often used as a model organism due to their size, ease of handling, and genetic similarity to humans. However, I couldn't find any specific medical definition related to "Long-Evans rats" as they are not a medical condition or disease.

Ambystoma mexicanum is the scientific name for the axolotl, a type of salamander that is native to Mexico. The axolotl is also known as the Mexican walking fish, although it is not actually a fish but an amphibian. It is unique because it exhibits neoteny, which means it can remain in its larval form throughout its entire life and never undergo complete metamorphosis into a terrestrial form.

The axolotl is a popular organism in scientific research due to its ability to regenerate lost body parts, including limbs, spinal cord, heart, and other organs. This has made it an important model organism for studying the mechanisms of regeneration and repair in mammals, including humans.

"Drosophila" is a genus of small flies, also known as fruit flies. The most common species used in scientific research is "Drosophila melanogaster," which has been a valuable model organism for many areas of biological and medical research, including genetics, developmental biology, neurobiology, and aging.

The use of Drosophila as a model organism has led to numerous important discoveries in genetics and molecular biology, such as the identification of genes that are associated with human diseases like cancer, Parkinson's disease, and obesity. The short reproductive cycle, large number of offspring, and ease of genetic manipulation make Drosophila a powerful tool for studying complex biological processes.

Efferent pathways refer to the neural connections that carry signals from the central nervous system (CNS), which includes the brain and spinal cord, to the peripheral effectors such as muscles and glands. These pathways are responsible for the initiation and control of motor responses, as well as regulating various autonomic functions.

Efferent pathways can be divided into two main types:

1. Somatic efferent pathways: These pathways carry signals from the CNS to the skeletal muscles, enabling voluntary movements and postural control. The final common pathway for somatic motor innervation is the alpha-motor neuron, which synapses directly onto skeletal muscle fibers.
2. Autonomic efferent pathways: These pathways regulate the function of internal organs, smooth muscles, and glands. They are further divided into two subtypes: sympathetic and parasympathetic. The sympathetic system is responsible for the 'fight or flight' response, while the parasympathetic system promotes rest and digestion. Both systems use a two-neuron chain to transmit signals from the CNS to the effector organs. The preganglionic neuron has its cell body in the CNS and synapses with the postganglionic neuron in an autonomic ganglion located near the effector organ. The postganglionic neuron then innervates the target organ or tissue.

In summary, efferent pathways are the neural connections that carry signals from the CNS to peripheral effectors, enabling motor responses and regulating various autonomic functions. They can be divided into somatic and autonomic efferent pathways, with further subdivisions within the autonomic system.

"Bees" are not a medical term, as they refer to various flying insects belonging to the Apidae family in the Apoidea superfamily. They are known for their role in pollination and honey production. If you're looking for medical definitions or information, please provide relevant terms.

"Pharmaceutical solutions" is a term that refers to medications or drugs that are formulated in a liquid state, as opposed to solid forms like tablets or capsules. These solutions are typically created by dissolving the active pharmaceutical ingredient (API) in a solvent, such as water or ethanol, along with other excipients that help stabilize and preserve the solution.

Pharmaceutical solutions can be administered to patients through various routes, including oral, intravenous, subcutaneous, or intramuscular injection, depending on the desired site of action and the specific properties of the drug. Some examples of pharmaceutical solutions include antibiotic infusions, pain medications, and electrolyte replacement drinks.

It's important to note that the term "pharmaceutical solutions" can also refer more broadly to the process of developing and manufacturing drugs, as well as to the industry as a whole. However, in a medical context, it most commonly refers to liquid medications.

Satiety response is a term used in the field of nutrition and physiology to describe the feeling of fullness or satisfaction that follows food consumption. It is a complex process regulated by several factors, including the mechanical and chemical signals generated during digestion, hormonal responses, and psychological factors. The satiety response helps control food intake and energy balance by inhibiting further eating until the body has had enough time to metabolize and absorb the nutrients from the meal.

The satiety response can be influenced by various factors such as the type, volume, and texture of food consumed, as well as individual differences in appetite regulation and metabolism. Understanding the mechanisms underlying the satiety response is important for developing strategies to promote healthy eating behaviors and prevent overeating, which can contribute to obesity and other health problems.

Brain-Derived Neurotrophic Factor (BDNF) is a type of protein called a neurotrophin, which is involved in the growth and maintenance of neurons (nerve cells) in the brain. BDNFA is encoded by the BDNF gene and is widely expressed throughout the central nervous system. It plays an essential role in supporting the survival of existing neurons, encouraging the growth and differentiation of new neurons and synapses, and contributing to neuroplasticity - the ability of the brain to change and adapt as a result of experience. Low levels of BDNF have been associated with several neurological disorders, including depression, Alzheimer's disease, and Huntington's disease.

"Primed In Situ Labeling" (PRINS) is not a widely recognized medical term, but it is a technique used in molecular biology and pathology. Here's a definition of the PRINS technique:

Primed In Situ Labeling (PRINS) is a cytogenetic method that allows for the detection and visualization of specific DNA sequences within chromosomes or interphase nuclei through fluorescence in situ hybridization (FISH). The technique involves denaturing double-stranded DNA in fixed cells, followed by annealing a primer to a specific target sequence. A DNA polymerase then extends the primer, incorporating labeled nucleotides that can be visualized under a fluorescence microscope.

The PRINS technique offers several advantages over traditional FISH methods, including higher sensitivity and specificity, lower background signal, and the ability to analyze multiple targets simultaneously using different colored probes. It is commonly used in the diagnosis and monitoring of various genetic disorders, cancer, and infectious diseases.

I'm sorry for any confusion, but "Insect Proteins" is not a recognized medical term. However, I can provide some information about insect protein from a nutritional and food science perspective.

Insect proteins refer to the proteins that are obtained from insects. Insects are a rich source of protein, and their protein content varies by species. For example, mealworms and crickets have been found to contain approximately 47-63% and 60-72% protein by dry weight, respectively.

In recent years, insect proteins have gained attention as a potential sustainable source of nutrition due to their high protein content, low environmental impact, and the ability to convert feed into protein more efficiently compared to traditional livestock. Insect proteins can be used in various applications such as food and feed additives, nutritional supplements, and even cosmetics.

However, it's important to note that the use of insect proteins in human food is not widely accepted in many Western countries due to cultural and regulatory barriers. Nonetheless, research and development efforts continue to explore the potential benefits and applications of insect proteins in the global food system.

The olfactory pathways refer to the neural connections and structures involved in the sense of smell. The process begins with odor molecules that are inhaled through the nostrils, where they bind to specialized receptor cells located in the upper part of the nasal cavity, known as the olfactory epithelium.

These receptor cells then transmit signals via the olfactory nerve (cranial nerve I) to the olfactory bulb, a structure at the base of the brain. Within the olfactory bulb, the signals are processed and relayed through several additional structures, including the olfactory tract, lateral olfactory striae, and the primary olfactory cortex (located within the piriform cortex).

From there, information about odors is further integrated with other sensory systems and cognitive functions in higher-order brain regions, such as the limbic system, thalamus, and hippocampus. This complex network of olfactory pathways allows us to perceive and recognize various scents and plays a role in emotional responses, memory formation, and feeding behaviors.

In medical terms, the mouth is officially referred to as the oral cavity. It is the first part of the digestive tract and includes several structures: the lips, vestibule (the space enclosed by the lips and teeth), teeth, gingiva (gums), hard and soft palate, tongue, floor of the mouth, and salivary glands. The mouth is responsible for several functions including speaking, swallowing, breathing, and eating, as it is the initial point of ingestion where food is broken down through mechanical and chemical processes, beginning the digestive process.

Brain mapping is a broad term that refers to the techniques used to understand the structure and function of the brain. It involves creating maps of the various cognitive, emotional, and behavioral processes in the brain by correlating these processes with physical locations or activities within the nervous system. Brain mapping can be accomplished through a variety of methods, including functional magnetic resonance imaging (fMRI), positron emission tomography (PET) scans, electroencephalography (EEG), and others. These techniques allow researchers to observe which areas of the brain are active during different tasks or thoughts, helping to shed light on how the brain processes information and contributes to our experiences and behaviors. Brain mapping is an important area of research in neuroscience, with potential applications in the diagnosis and treatment of neurological and psychiatric disorders.

In the context of medicine, "odors" refer to smells or scents that are produced by certain medical conditions, substances, or bodily functions. These odors can sometimes provide clues about underlying health issues. For example, sweet-smelling urine could indicate diabetes, while foul-smelling breath might suggest a dental problem or gastrointestinal issue. However, it's important to note that while odors can sometimes be indicative of certain medical conditions, they are not always reliable diagnostic tools and should be considered in conjunction with other symptoms and medical tests.

Purinergic P2X3 receptors are a type of ligand-gated ion channel that are activated by the binding of adenosine triphosphate (ATP) and related nucleotides. These receptors are primarily expressed on sensory neurons, including nociceptive neurons that detect and transmit pain signals.

P2X3 receptors are homomeric or heteromeric complexes composed of P2X3 subunits, which form a functional ion channel upon activation by ATP. These receptors play an important role in the transmission of nociceptive information from the periphery to the central nervous system.

Activation of P2X3 receptors leads to the opening of the ion channel and the influx of cations, such as calcium and sodium ions, into the neuron. This depolarizes the membrane and can trigger action potentials that transmit pain signals to the brain.

P2X3 receptors have been implicated in various pain conditions, including inflammatory pain, neuropathic pain, and cancer-related pain. As a result, P2X3 receptor antagonists are being investigated as potential therapeutic agents for the treatment of chronic pain.

Phospholipase C beta (PLCβ) is an enzyme that plays a crucial role in intracellular signaling transduction pathways. It is a subtype of Phospholipase C, which is responsible for cleaving phospholipids into secondary messengers, thereby mediating various cellular responses.

PLCβ is activated by G protein-coupled receptors (GPCRs) and can be found in various tissues throughout the body. Once activated, PLCβ hydrolyzes a specific phospholipid, PIP2 (Phosphatidylinositol 4,5-bisphosphate), into two secondary messengers: IP3 (Inositol 1,4,5-trisphosphate) and DAG (Diacylglycerol). These second messengers then trigger a series of downstream events, such as calcium mobilization and protein kinase C activation, which ultimately lead to changes in cell functions, including gene expression, cell growth, differentiation, and secretion.

There are four isoforms of PLCβ (PLCβ1, PLCβ2, PLCβ3, and PLCβ4) that differ in their tissue distribution, regulation, and substrate specificity. Mutations or dysregulation of PLCβ have been implicated in several diseases, including cancer, cardiovascular disease, and neurological disorders.

The term "drinking" is commonly used to refer to the consumption of beverages, but in a medical context, it usually refers to the consumption of alcoholic drinks. According to the Merriam-Webster Medical Dictionary, "drinking" is defined as:

1. The act or habit of swallowing liquid (such as water, juice, or alcohol)
2. The ingestion of alcoholic beverages

It's important to note that while moderate drinking may not pose significant health risks for some individuals, excessive or binge drinking can lead to a range of negative health consequences, including addiction, liver disease, heart disease, and increased risk of injury or violence.

Cranial nerves are a set of twelve pairs of nerves that originate from the brainstem and skull, rather than the spinal cord. These nerves are responsible for transmitting sensory information (such as sight, smell, hearing, and taste) to the brain, as well as controlling various muscles in the head and neck (including those involved in chewing, swallowing, and eye movement). Each cranial nerve has a specific function and is named accordingly. For example, the optic nerve (cranial nerve II) transmits visual information from the eyes to the brain, while the vagus nerve (cranial nerve X) controls parasympathetic functions in the body such as heart rate and digestion.

Appetitive behavior is a term used in the field of psychology and neuroscience to refer to actions or behaviors that are performed in order to obtain a reward or positive reinforcement. These behaviors are often driven by basic biological needs, such as hunger, thirst, or the need for social interaction. They can also be influenced by learned associations and past experiences.

In the context of medical terminology, appetitive behavior may be used to describe a patient's level of interest in food or their desire to eat. For example, a patient with a good appetite may have a strong desire to eat and may seek out food regularly, while a patient with a poor appetite may have little interest in food and may need to be encouraged to eat.

Appetitive behavior is regulated by a complex interplay of hormonal, neural, and psychological factors. Disruptions in these systems can lead to changes in appetitive behavior, such as increased or decreased hunger and eating. Appetitive behavior is an important area of study in the field of obesity research, as it is thought that understanding the underlying mechanisms that drive appetitive behavior may help to develop more effective treatments for weight management.

Ionotropic glutamate receptors (iGluRs) are a type of neurotransmitter receptor for the excitatory neurotransmitter glutamate. They are ligand-gated ion channels, meaning that upon binding of glutamate, they undergo a conformational change that opens a pore, allowing ions to flow through the membrane. This ion flux can lead to depolarization or hyperpolarization of the postsynaptic neuron and is critical for excitatory neurotransmission in the central nervous system.

iGluRs are divided into three main subfamilies based on their pharmacological and structural properties: AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors, kainate receptors, and NMDA (N-methyl-D-aspartate) receptors. Each subfamily has distinct properties and plays specific roles in synaptic transmission and plasticity.

AMPA receptors are permeable to sodium and potassium ions and mediate fast excitatory neurotransmission. Kainate receptors are also permeable to sodium and potassium ions, but they can also allow calcium ions to flow in under certain conditions, contributing to slower excitatory transmission and synaptic plasticity. NMDA receptors are unique among iGluRs because they are highly permeable to calcium ions, which play a critical role in synaptic plasticity and learning and memory processes.

Abnormalities in iGluR function have been implicated in various neurological disorders, including epilepsy, neurodegenerative diseases, and psychiatric conditions. Therefore, iGluRs are an important target for drug development and therapeutic intervention.

The lateral hypothalamic area (LHA) is a region in the hypothalamus, which is a part of the brain that plays a crucial role in regulating various autonomic functions and maintaining homeostasis. The LHA is located laterally to the third ventricle and contains several neuronal populations that are involved in diverse physiological processes such as feeding behavior, energy balance, sleep-wake regulation, and neuroendocrine function.

Some of the key neurons found in the LHA include orexin/hypocretin neurons, melanin-concentrating hormone (MCH) neurons, and agouti-related protein (AGRP) neurons. These neurons release neurotransmitters and neuropeptides that modulate various physiological functions, including appetite regulation, energy expenditure, and arousal. Dysfunction in the LHA has been implicated in several neurological and psychiatric disorders, such as narcolepsy, obesity, and depression.

Inosine monophosphate (IMP) is a nucleotide that plays a crucial role in the metabolic pathways of energy production and purine synthesis in cells. It is an ester of the nucleoside inosine and phosphoric acid. IMP is an important intermediate in the conversion of adenosine monophosphate (AMP) to guanosine monophosphate (GMP) in the purine nucleotide cycle, which is critical for maintaining the balance of purine nucleotides in the body. Additionally, IMP can be converted back to AMP through the action of the enzyme adenylosuccinate lyase. IMP has been studied for its potential therapeutic benefits in various medical conditions, including neurodegenerative disorders and ischemia-reperfusion injury.

Wheat germ agglutinins (WGA) are proteins found in wheat germ that have the ability to bind to specific carbohydrate structures, such as N-acetylglucosamine and sialic acid, which are present on the surface of many cells in the human body. WGA is a type of lectin, a group of proteins that can agglutinate, or clump together, red blood cells and bind to specific sugars on cell membranes.

WGA has been studied for its potential effects on various biological processes, including inflammation, immune response, and gut barrier function. Some research suggests that WGA may interact with the gut epithelium and affect intestinal permeability, potentially contributing to the development of gastrointestinal symptoms in some individuals. However, more research is needed to fully understand the clinical significance of these findings.

It's worth noting that while WGA has been studied for its potential biological effects, it is not currently recognized as a major allergen or toxic component of wheat. However, some people may still choose to avoid foods containing WGA due to personal dietary preferences or sensitivities.

Electric stimulation, also known as electrical nerve stimulation or neuromuscular electrical stimulation, is a therapeutic treatment that uses low-voltage electrical currents to stimulate nerves and muscles. It is often used to help manage pain, promote healing, and improve muscle strength and mobility. The electrical impulses can be delivered through electrodes placed on the skin or directly implanted into the body.

In a medical context, electric stimulation may be used for various purposes such as:

1. Pain management: Electric stimulation can help to block pain signals from reaching the brain and promote the release of endorphins, which are natural painkillers produced by the body.
2. Muscle rehabilitation: Electric stimulation can help to strengthen muscles that have become weak due to injury, illness, or surgery. It can also help to prevent muscle atrophy and improve range of motion.
3. Wound healing: Electric stimulation can promote tissue growth and help to speed up the healing process in wounds, ulcers, and other types of injuries.
4. Urinary incontinence: Electric stimulation can be used to strengthen the muscles that control urination and reduce symptoms of urinary incontinence.
5. Migraine prevention: Electric stimulation can be used as a preventive treatment for migraines by applying electrical impulses to specific nerves in the head and neck.

It is important to note that electric stimulation should only be administered under the guidance of a qualified healthcare professional, as improper use can cause harm or discomfort.

Genes in insects refer to the hereditary units of DNA that are passed down from parents to offspring and contain the instructions for the development, function, and reproduction of an organism. These genetic materials are located within the chromosomes in the nucleus of insect cells. They play a crucial role in determining various traits such as physical characteristics, behavior, and susceptibility to diseases.

Insect genes, like those of other organisms, consist of exons (coding regions) that contain information for protein synthesis and introns (non-coding regions) that are removed during the process of gene expression. The expression of insect genes is regulated by various factors such as transcription factors, enhancers, and silencers, which bind to specific DNA sequences to activate or repress gene transcription.

Understanding the genetic makeup of insects has important implications for various fields, including agriculture, public health, and evolutionary biology. For example, genes associated with insect pests' resistance to pesticides can be identified and targeted to develop more effective control strategies. Similarly, genes involved in disease transmission by insect vectors such as mosquitoes can be studied to develop novel interventions for preventing the spread of infectious diseases.

The medical definition of "eating" refers to the process of consuming and ingesting food or nutrients into the body. This process typically involves several steps, including:

1. Food preparation: This may involve cleaning, chopping, cooking, or combining ingredients to make them ready for consumption.
2. Ingestion: The act of taking food or nutrients into the mouth and swallowing it.
3. Digestion: Once food is ingested, it travels down the esophagus and enters the stomach, where it is broken down by enzymes and acids to facilitate absorption of nutrients.
4. Absorption: Nutrients are absorbed through the walls of the small intestine and transported to cells throughout the body for use as energy or building blocks for growth and repair.
5. Elimination: Undigested food and waste products are eliminated from the body through the large intestine (colon) and rectum.

Eating is an essential function that provides the body with the nutrients it needs to maintain health, grow, and repair itself. Disorders of eating, such as anorexia nervosa or bulimia nervosa, can have serious consequences for physical and mental health.

A sodium-restricted diet is a meal plan designed to limit the amount of sodium (salt) intake. The recommended daily sodium intake for adults is less than 2,300 milligrams (mg), but for those with certain medical conditions such as high blood pressure, heart failure, or chronic kidney disease, a lower daily sodium limit of 1,500 to 2,000 mg may be recommended.

A sodium-restricted diet typically involves avoiding processed and packaged foods, which are often high in sodium, and limiting the use of salt when cooking or at the table. Fresh fruits, vegetables, lean proteins, and whole grains are encouraged as they are naturally low in sodium. It is important to read food labels carefully, as some foods may contain hidden sources of sodium.

Adhering to a sodium-restricted diet can help manage blood pressure, reduce fluid retention, and decrease the risk of heart disease and stroke. However, it is important to consult with a healthcare provider or a registered dietitian before starting any new diet plan to ensure that it meets individual nutritional needs and medical conditions.

Scanning electron microscopy (SEM) is a type of electron microscopy that uses a focused beam of electrons to scan the surface of a sample and produce a high-resolution image. In SEM, a beam of electrons is scanned across the surface of a specimen, and secondary electrons are emitted from the sample due to interactions between the electrons and the atoms in the sample. These secondary electrons are then detected by a detector and used to create an image of the sample's surface topography. SEM can provide detailed images of the surface of a wide range of materials, including metals, polymers, ceramics, and biological samples. It is commonly used in materials science, biology, and electronics for the examination and analysis of surfaces at the micro- and nanoscale.

'Caenorhabditis elegans' is a species of free-living, transparent nematode (roundworm) that is widely used as a model organism in scientific research, particularly in the fields of biology and genetics. It has a simple anatomy, short lifespan, and fully sequenced genome, making it an ideal subject for studying various biological processes and diseases.

Some notable features of C. elegans include:

* Small size: Adult hermaphrodites are about 1 mm in length.
* Short lifespan: The average lifespan of C. elegans is around 2-3 weeks, although some strains can live up to 4 weeks under laboratory conditions.
* Development: C. elegans has a well-characterized developmental process, with adults developing from eggs in just 3 days at 20°C.
* Transparency: The transparent body of C. elegans allows researchers to observe its internal structures and processes easily.
* Genetics: C. elegans has a fully sequenced genome, which contains approximately 20,000 genes. Many of these genes have human homologs, making it an excellent model for studying human diseases.
* Neurobiology: C. elegans has a simple nervous system, with only 302 neurons in the hermaphrodite and 383 in the male. This simplicity makes it an ideal organism for studying neural development, function, and behavior.

Research using C. elegans has contributed significantly to our understanding of various biological processes, including cell division, apoptosis, aging, learning, and memory. Additionally, studies on C. elegans have led to the discovery of many genes associated with human diseases such as cancer, neurodegenerative disorders, and metabolic conditions.

A gastric fistula is an abnormal connection or passage between the stomach and another organ or the skin surface. This condition can occur as a result of complications from surgery, injury, infection, or certain diseases such as cancer. Symptoms may include persistent drainage from the site of the fistula, pain, malnutrition, and infection. Treatment typically involves surgical repair of the fistula and management of any underlying conditions.

Potassium chloride is an essential electrolyte that is often used in medical settings as a medication. It's a white, crystalline salt that is highly soluble in water and has a salty taste. In the body, potassium chloride plays a crucial role in maintaining fluid and electrolyte balance, nerve function, and muscle contraction.

Medically, potassium chloride is commonly used to treat or prevent low potassium levels (hypokalemia) in the blood. Hypokalemia can occur due to various reasons such as certain medications, kidney diseases, vomiting, diarrhea, or excessive sweating. Potassium chloride is available in various forms, including tablets, capsules, and liquids, and it's usually taken by mouth.

It's important to note that potassium chloride should be used with caution and under the supervision of a healthcare provider, as high levels of potassium (hyperkalemia) can be harmful and even life-threatening. Hyperkalemia can cause symptoms such as muscle weakness, irregular heartbeat, and cardiac arrest.

Association learning, also known as associative learning, is a type of learning in which an individual learns to associate two stimuli or a response with a particular outcome. This can occur through classical conditioning or operant conditioning.

In classical conditioning, first described by Ivan Pavlov, an initially neutral stimulus (the conditioned stimulus) is repeatedly paired with a biologically significant stimulus (the unconditioned stimulus), until the conditioned stimulus elicits a response (the conditioned response) similar to that of the unconditioned stimulus. For example, a dog may learn to salivate at the sound of a bell if the bell is repeatedly rung just before it is fed.

In operant conditioning, described by B.F. Skinner, behavior is modified by its consequences, with desired behaviors being reinforced and undesired behaviors being punished. For example, a child may learn to put their toys away if they are given a reward for doing so.

Association learning is an important mechanism in the acquisition of many types of knowledge and skills, and it plays a key role in the development and modification of behavior.

Oviposition is a medical/biological term that refers to the process of laying or depositing eggs by female organisms, including birds, reptiles, insects, and fish. In humans and other mammals, the term is not applicable since they give birth to live young rather than laying eggs.

'Nervous system physiological phenomena' refer to the functions, activities, and processes that occur within the nervous system in a healthy or normal state. This includes:

1. Neuronal Activity: The transmission of electrical signals (action potentials) along neurons, which allows for communication between different cells and parts of the nervous system.

2. Neurotransmission: The release and binding of neurotransmitters to receptors on neighboring cells, enabling the transfer of information across the synapse or junction between two neurons.

3. Sensory Processing: The conversion of external stimuli into electrical signals by sensory receptors, followed by the transmission and interpretation of these signals within the central nervous system (brain and spinal cord).

4. Motor Function: The generation and execution of motor commands, allowing for voluntary movement and control of muscles and glands.

5. Autonomic Function: The regulation of internal organs and glands through the sympathetic and parasympathetic divisions of the autonomic nervous system, maintaining homeostasis within the body.

6. Cognitive Processes: Higher brain functions such as perception, attention, memory, language, learning, and emotion, which are supported by complex neural networks and interactions.

7. Sleep-Wake Cycle: The regulation of sleep and wakefulness through interactions between the brainstem, thalamus, hypothalamus, and basal forebrain, ensuring proper rest and recovery.

8. Development and Plasticity: The growth, maturation, and adaptation of the nervous system throughout life, including processes such as neuronal migration, synaptogenesis, and neural plasticity.

9. Endocrine Regulation: The interaction between the nervous system and endocrine system, with the hypothalamus playing a key role in controlling hormone release and maintaining homeostasis.

10. Immune Function: The communication between the nervous system and immune system, allowing for the coordination of responses to infection, injury, or stress.

Trehalose is a type of disaccharide, which is a sugar made up of two monosaccharides. It consists of two glucose molecules joined together in a way that makes it more stable and resistant to breakdown by enzymes and heat. This property allows trehalose to be used as a protectant for biological materials during freeze-drying and storage, as well as a food additive as a sweetener and preservative.

Trehalose is found naturally in some plants, fungi, insects, and microorganisms, where it serves as a source of energy and protection against environmental stresses such as drought, heat, and cold. In recent years, there has been interest in the potential therapeutic uses of trehalose for various medical conditions, including neurodegenerative diseases, diabetes, and cancer.

Medically speaking, trehalose may be used in some pharmaceutical formulations as an excipient or stabilizer, and it is also being investigated as a potential therapeutic agent for various diseases. However, its use as a medical treatment is still not widely established, and further research is needed to determine its safety and efficacy.

'Caenorhabditis elegans' (C. elegans) is a type of free-living, transparent nematode (roundworm) that is often used as a model organism in scientific research. C. elegans proteins refer to the various types of protein molecules that are produced by the organism's genes and play crucial roles in maintaining its biological functions.

Proteins are complex molecules made up of long chains of amino acids, and they are involved in virtually every cellular process, including metabolism, DNA replication, signal transduction, and transportation of molecules within the cell. In C. elegans, proteins are encoded by genes, which are transcribed into messenger RNA (mRNA) molecules that are then translated into protein sequences by ribosomes.

Studying C. elegans proteins is important for understanding the basic biology of this organism and can provide insights into more complex biological systems, including humans. Because C. elegans has a relatively simple nervous system and a short lifespan, it is often used to study neurobiology, aging, and development. Additionally, because many of the genes and proteins in C. elegans have counterparts in other organisms, including humans, studying them can provide insights into human disease processes and potential therapeutic targets.

Physical stimulation, in a medical context, refers to the application of external forces or agents to the body or its tissues to elicit a response. This can include various forms of touch, pressure, temperature, vibration, or electrical currents. The purpose of physical stimulation may be therapeutic, as in the case of massage or physical therapy, or diagnostic, as in the use of reflex tests. It is also used in research settings to study physiological responses and mechanisms.

In a broader sense, physical stimulation can also refer to the body's exposure to physical activity or exercise, which can have numerous health benefits, including improving cardiovascular function, increasing muscle strength and flexibility, and reducing the risk of chronic diseases.

In the context of medicine, "salts" often refers to ionic compounds that are formed when an acid and a base react together. The resulting product of this neutralization reaction is composed of cations (positively charged ions) and anions (negatively charged ions), which combine to form a salt.

Salts can also be formed from the reaction between a weak acid and a strong base, or between a strong acid and a weak base. The resulting salt will have properties that are different from those of the reactants, including its solubility in water, pH, and taste. In some cases, salts can be used for therapeutic purposes, such as potassium chloride (KCl) or sodium bicarbonate (NaHCO3), while others may be harmful and pose a risk to human health.

It's important to note that the term "salts" can also refer to organic compounds that contain a functional group consisting of a single bond between a carbon atom and a halogen atom, such as sodium chloride (NaCl) or potassium iodide (KI). These types of salts are not formed from acid-base reactions but rather through ionic bonding between a metal and a nonmetal.

Transient Receptor Potential Melastatin (TRPM) cation channels are a subfamily of the transient receptor potential (TRP) channel superfamily, which are non-selective cation channels that play important roles in various cellular processes such as sensory perception, cell proliferation, and migration.

The TRPM subfamily consists of eight members (TRPM1-8), each with distinct functional properties and expression patterns. These channels are permeable to both monovalent and divalent cations, including calcium (Ca^2+^) and magnesium (Mg^2+^).

TRPM channels can be activated by a variety of stimuli, such as changes in temperature, voltage, osmolarity, and chemical ligands. For example, TRPM8 is known to be activated by cold temperatures and menthol, while TRPV1 is activated by heat and capsaicin.

Dysregulation of TRPM channels has been implicated in various pathological conditions, including pain, neurodegenerative diseases, and cancer. Therefore, understanding the structure and function of these channels may provide insights into potential therapeutic targets for these conditions.

Analysis of Variance (ANOVA) is a statistical technique used to compare the means of two or more groups and determine whether there are any significant differences between them. It is a way to analyze the variance in a dataset to determine whether the variability between groups is greater than the variability within groups, which can indicate that the groups are significantly different from one another.

ANOVA is based on the concept of partitioning the total variance in a dataset into two components: variance due to differences between group means (also known as "between-group variance") and variance due to differences within each group (also known as "within-group variance"). By comparing these two sources of variance, ANOVA can help researchers determine whether any observed differences between groups are statistically significant, or whether they could have occurred by chance.

ANOVA is a widely used technique in many areas of research, including biology, psychology, engineering, and business. It is often used to compare the means of two or more experimental groups, such as a treatment group and a control group, to determine whether the treatment had a significant effect. ANOVA can also be used to compare the means of different populations or subgroups within a population, to identify any differences that may exist between them.

Cholesteatoma, middle ear is a medical condition characterized by the abnormal growth of skin cells (keratinizing squamous epithelium) within the middle ear space. This skin cells accumulation forms a pearly, white, or gray mass that can erode and destroy surrounding structures such as the ossicles (the tiny bones in the middle ear), the mastoid process (a bony prominence behind the ear), and even the inner ear or brain.

Cholesteatomas can be congenital (present at birth) or acquired (develop later in life). Acquired cholesteatomas are more common and usually result from repeated middle ear infections that cause a retraction pocket of the eardrum, which then traps skin cells leading to their abnormal growth. Symptoms of cholesteatoma may include hearing loss, ear drainage, ear pain, vertigo, or facial weakness. Treatment typically involves surgical removal of the cholesteatoma and restoration of any damaged structures.

"Catfishes" is a term that refers to a group of ray-finned fish belonging to the order Siluriformes. However, in a medical or clinical context, "catfishing" has taken on a different meaning. It is a term used to describe the phenomenon of creating a false online identity to deceive someone, particularly in social media or dating websites. The person who creates the fake identity is called a "catfish." This behavior can have serious emotional and psychological consequences for those who are being deceived.

Medical definitions of water generally describe it as a colorless, odorless, tasteless liquid that is essential for all forms of life. It is a universal solvent, making it an excellent medium for transporting nutrients and waste products within the body. Water constitutes about 50-70% of an individual's body weight, depending on factors such as age, sex, and muscle mass.

In medical terms, water has several important functions in the human body:

1. Regulation of body temperature through perspiration and respiration.
2. Acting as a lubricant for joints and tissues.
3. Facilitating digestion by helping to break down food particles.
4. Transporting nutrients, oxygen, and waste products throughout the body.
5. Helping to maintain healthy skin and mucous membranes.
6. Assisting in the regulation of various bodily functions, such as blood pressure and heart rate.

Dehydration can occur when an individual does not consume enough water or loses too much fluid due to illness, exercise, or other factors. This can lead to a variety of symptoms, including dry mouth, fatigue, dizziness, and confusion. Severe dehydration can be life-threatening if left untreated.

In the context of medicine, "cues" generally refer to specific pieces of information or signals that can help healthcare professionals recognize and respond to a particular situation or condition. These cues can come in various forms, such as:

1. Physical examination findings: For example, a patient's abnormal heart rate or blood pressure reading during a physical exam may serve as a cue for the healthcare professional to investigate further.
2. Patient symptoms: A patient reporting chest pain, shortness of breath, or other concerning symptoms can act as a cue for a healthcare provider to consider potential diagnoses and develop an appropriate treatment plan.
3. Laboratory test results: Abnormal findings on laboratory tests, such as elevated blood glucose levels or abnormal liver function tests, may serve as cues for further evaluation and diagnosis.
4. Medical history information: A patient's medical history can provide valuable cues for healthcare professionals when assessing their current health status. For example, a history of smoking may increase the suspicion for chronic obstructive pulmonary disease (COPD) in a patient presenting with respiratory symptoms.
5. Behavioral or environmental cues: In some cases, behavioral or environmental factors can serve as cues for healthcare professionals to consider potential health risks. For instance, exposure to secondhand smoke or living in an area with high air pollution levels may increase the risk of developing respiratory conditions.

Overall, "cues" in a medical context are essential pieces of information that help healthcare professionals make informed decisions about patient care and treatment.

Immunohistochemistry (IHC) is a technique used in pathology and laboratory medicine to identify specific proteins or antigens in tissue sections. It combines the principles of immunology and histology to detect the presence and location of these target molecules within cells and tissues. This technique utilizes antibodies that are specific to the protein or antigen of interest, which are then tagged with a detection system such as a chromogen or fluorophore. The stained tissue sections can be examined under a microscope, allowing for the visualization and analysis of the distribution and expression patterns of the target molecule in the context of the tissue architecture. Immunohistochemistry is widely used in diagnostic pathology to help identify various diseases, including cancer, infectious diseases, and immune-mediated disorders.

Salivation is the process of producing and secreting saliva by the salivary glands in the mouth. It is primarily a reflex response to various stimuli such as thinking about or tasting food, chewing, and speaking. Saliva plays a crucial role in digestion by moistening food and helping to create a food bolus that can be swallowed easily. Additionally, saliva contains enzymes like amylase which begin the process of digesting carbohydrates even before food enters the stomach. Excessive salivation is known as hypersalivation or ptyalism, while reduced salivation is called xerostomia.

Epithelium is the tissue that covers the outer surface of the body, lines the internal cavities and organs, and forms various glands. It is composed of one or more layers of tightly packed cells that have a uniform shape and size, and rest on a basement membrane. Epithelial tissues are avascular, meaning they do not contain blood vessels, and are supplied with nutrients by diffusion from the underlying connective tissue.

Epithelial cells perform a variety of functions, including protection, secretion, absorption, excretion, and sensation. They can be classified based on their shape and the number of cell layers they contain. The main types of epithelium are:

1. Squamous epithelium: composed of flat, scalelike cells that fit together like tiles on a roof. It forms the lining of blood vessels, air sacs in the lungs, and the outermost layer of the skin.
2. Cuboidal epithelium: composed of cube-shaped cells with equal height and width. It is found in glands, tubules, and ducts.
3. Columnar epithelium: composed of tall, rectangular cells that are taller than they are wide. It lines the respiratory, digestive, and reproductive tracts.
4. Pseudostratified epithelium: appears stratified or layered but is actually made up of a single layer of cells that vary in height. The nuclei of these cells appear at different levels, giving the tissue a stratified appearance. It lines the respiratory and reproductive tracts.
5. Transitional epithelium: composed of several layers of cells that can stretch and change shape to accommodate changes in volume. It is found in the urinary bladder and ureters.

Epithelial tissue provides a barrier between the internal and external environments, protecting the body from physical, chemical, and biological damage. It also plays a crucial role in maintaining homeostasis by regulating the exchange of substances between the body and its environment.

I believe there may be some confusion in your question. "Moths" are not a medical term, but rather they are a group of insects closely related to butterflies. They belong to the order Lepidoptera and are characterized by their scales covering their wings and body. If you have any questions about moths or if you meant to ask something else, please let me know!

Evoked potentials (EPs) are medical tests that measure the electrical activity in the brain or spinal cord in response to specific sensory stimuli, such as sight, sound, or touch. These tests are often used to help diagnose and monitor conditions that affect the nervous system, such as multiple sclerosis, brainstem tumors, and spinal cord injuries.

There are several types of EPs, including:

1. Visual Evoked Potentials (VEPs): These are used to assess the function of the visual pathway from the eyes to the back of the brain. A patient is typically asked to look at a patterned image or flashing light while electrodes placed on the scalp record the electrical responses.
2. Brainstem Auditory Evoked Potentials (BAEPs): These are used to evaluate the function of the auditory nerve and brainstem. Clicking sounds are presented to one or both ears, and electrodes placed on the scalp measure the response.
3. Somatosensory Evoked Potentials (SSEPs): These are used to assess the function of the peripheral nerves and spinal cord. Small electrical shocks are applied to a nerve at the wrist or ankle, and electrodes placed on the scalp record the response as it travels up the spinal cord to the brain.
4. Motor Evoked Potentials (MEPs): These are used to assess the function of the motor pathways in the brain and spinal cord. A magnetic or electrical stimulus is applied to the brain or spinal cord, and electrodes placed on a muscle measure the response as it travels down the motor pathway.

EPs can help identify abnormalities in the nervous system that may not be apparent through other diagnostic tests, such as imaging studies or clinical examinations. They are generally safe, non-invasive procedures with few risks or side effects.

Carbohydrates are a major nutrient class consisting of organic compounds that primarily contain carbon, hydrogen, and oxygen atoms. They are classified as saccharides, which include monosaccharides (simple sugars), disaccharides (double sugars), oligosaccharides (short-chain sugars), and polysaccharides (complex carbohydrates).

Monosaccharides, such as glucose, fructose, and galactose, are the simplest form of carbohydrates. They consist of a single sugar molecule that cannot be broken down further by hydrolysis. Disaccharides, like sucrose (table sugar), lactose (milk sugar), and maltose (malt sugar), are formed from two monosaccharide units joined together.

Oligosaccharides contain a small number of monosaccharide units, typically less than 20, while polysaccharides consist of long chains of hundreds to thousands of monosaccharide units. Polysaccharides can be further classified into starch (found in plants), glycogen (found in animals), and non-starchy polysaccharides like cellulose, chitin, and pectin.

Carbohydrates play a crucial role in providing energy to the body, with glucose being the primary source of energy for most cells. They also serve as structural components in plants (cellulose) and animals (chitin), participate in various metabolic processes, and contribute to the taste, texture, and preservation of foods.

In the context of medicine and psychology, perception refers to the neurophysiological processes, cognitive abilities, and psychological experiences that enable an individual to interpret and make sense of sensory information from their environment. It involves the integration of various stimuli such as sight, sound, touch, taste, and smell to form a coherent understanding of one's surroundings, objects, events, or ideas.

Perception is a complex and active process that includes attention, pattern recognition, interpretation, and organization of sensory information. It can be influenced by various factors, including prior experiences, expectations, cultural background, emotional states, and cognitive biases. Alterations in perception may occur due to neurological disorders, psychiatric conditions, sensory deprivation or overload, drugs, or other external factors.

In a clinical setting, healthcare professionals often assess patients' perceptions of their symptoms, illnesses, or treatments to develop individualized care plans and improve communication and adherence to treatment recommendations.

Nerve regeneration is the process of regrowth and restoration of functional nerve connections following damage or injury to the nervous system. This complex process involves various cellular and molecular events, such as the activation of support cells called glia, the sprouting of surviving nerve fibers (axons), and the reformation of neural circuits. The goal of nerve regeneration is to enable the restoration of normal sensory, motor, and autonomic functions impaired due to nerve damage or injury.

The brain is the central organ of the nervous system, responsible for receiving and processing sensory information, regulating vital functions, and controlling behavior, movement, and cognition. It is divided into several distinct regions, each with specific functions:

1. Cerebrum: The largest part of the brain, responsible for higher cognitive functions such as thinking, learning, memory, language, and perception. It is divided into two hemispheres, each controlling the opposite side of the body.
2. Cerebellum: Located at the back of the brain, it is responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
3. Brainstem: Connects the cerebrum and cerebellum to the spinal cord, controlling vital functions such as breathing, heart rate, and blood pressure. It also serves as a relay center for sensory information and motor commands between the brain and the rest of the body.
4. Diencephalon: A region that includes the thalamus (a major sensory relay station) and hypothalamus (regulates hormones, temperature, hunger, thirst, and sleep).
5. Limbic system: A group of structures involved in emotional processing, memory formation, and motivation, including the hippocampus, amygdala, and cingulate gyrus.

The brain is composed of billions of interconnected neurons that communicate through electrical and chemical signals. It is protected by the skull and surrounded by three layers of membranes called meninges, as well as cerebrospinal fluid that provides cushioning and nutrients.

A dose-response relationship in the context of drugs refers to the changes in the effects or symptoms that occur as the dose of a drug is increased or decreased. Generally, as the dose of a drug is increased, the severity or intensity of its effects also increases. Conversely, as the dose is decreased, the effects of the drug become less severe or may disappear altogether.

The dose-response relationship is an important concept in pharmacology and toxicology because it helps to establish the safe and effective dosage range for a drug. By understanding how changes in the dose of a drug affect its therapeutic and adverse effects, healthcare providers can optimize treatment plans for their patients while minimizing the risk of harm.

The dose-response relationship is typically depicted as a curve that shows the relationship between the dose of a drug and its effect. The shape of the curve may vary depending on the drug and the specific effect being measured. Some drugs may have a steep dose-response curve, meaning that small changes in the dose can result in large differences in the effect. Other drugs may have a more gradual dose-response curve, where larger changes in the dose are needed to produce significant effects.

In addition to helping establish safe and effective dosages, the dose-response relationship is also used to evaluate the potential therapeutic benefits and risks of new drugs during clinical trials. By systematically testing different doses of a drug in controlled studies, researchers can identify the optimal dosage range for the drug and assess its safety and efficacy.

Operant conditioning is a type of learning in which behavior is modified by its consequences, either reinforcing or punishing the behavior. It was first described by B.F. Skinner and involves an association between a response (behavior) and a consequence (either reward or punishment). There are two types of operant conditioning: positive reinforcement, in which a desirable consequence follows a desired behavior, increasing the likelihood that the behavior will occur again; and negative reinforcement, in which a undesirable consequence is removed following a desired behavior, also increasing the likelihood that the behavior will occur again.

For example, if a child cleans their room (response) and their parent gives them praise or a treat (positive reinforcement), the child is more likely to clean their room again in the future. If a child is buckling their seatbelt in the car (response) and the annoying buzzer stops (negative reinforcement), the child is more likely to buckle their seatbelt in the future.

It's important to note that operant conditioning is a form of learning, not motivation. The behavior is modified by its consequences, regardless of the individual's internal state or intentions.

The septal nuclei are a collection of gray matter structures located in the basal forebrain, specifically in the septum pellucidum. They consist of several interconnected subnuclei that play important roles in various functions such as reward and reinforcement, emotional processing, learning, and memory.

The septal nuclei are primarily composed of GABAergic neurons (neurons that release the neurotransmitter gamma-aminobutyric acid or GABA) and receive inputs from several brain regions, including the hippocampus, amygdala, hypothalamus, and prefrontal cortex. They also send projections to various areas, including the thalamus, hypothalamus, and other limbic structures.

Stimulation of the septal nuclei has been associated with feelings of pleasure and reward, while damage or lesions can lead to changes in emotional behavior and cognitive functions. The septal nuclei are also involved in neuroendocrine regulation, particularly in relation to the hypothalamic-pituitary-adrenal (HPA) axis and the release of stress hormones.

Sexual behavior in animals refers to a variety of behaviors related to reproduction and mating that occur between members of the same species. These behaviors can include courtship displays, mating rituals, and various physical acts. The specific forms of sexual behavior displayed by a given species are influenced by a combination of genetic, hormonal, and environmental factors.

In some animals, sexual behavior is closely tied to reproductive cycles and may only occur during certain times of the year or under specific conditions. In other species, sexual behavior may be more frequent and less closely tied to reproduction, serving instead as a means of social bonding or communication.

It's important to note that while humans are animals, the term "sexual behavior" is often used in a more specific sense to refer to sexual activities between human beings. The study of sexual behavior in animals is an important area of research within the field of animal behavior and can provide insights into the evolutionary origins of human sexual behavior as well as the underlying mechanisms that drive it.

Sympathectomy is a surgical procedure that involves interrupting the sympathetic nerve pathways. These nerves are part of the autonomic nervous system, which controls involuntary bodily functions such as heart rate, blood pressure, sweating, and digestion. The goal of sympathectomy is to manage conditions like hyperhidrosis (excessive sweating), Raynaud's phenomenon, and certain types of chronic pain.

There are different types of sympathectomy, including thoracic sympathectomy (which targets the sympathetic nerves in the chest), lumbar sympathectomy (which targets the sympathetic nerves in the lower back), and cervical sympathectomy (which targets the sympathetic nerves in the neck). The specific type of procedure depends on the location of the affected nerves and the condition being treated.

Sympathectomy is usually performed using minimally invasive techniques, such as endoscopic surgery, which involves making small incisions and using specialized instruments to access the nerves. While sympathectomy can be effective in managing certain conditions, it carries risks such as nerve damage, bleeding, infection, and chronic pain.

Satiation is a term used in the field of nutrition and physiology, which refers to the feeling of fullness or satisfaction that one experiences after eating food. It is the point at which further consumption of food no longer adds to the sensation of hunger or the desire to eat. This response is influenced by various factors such as the type and amount of food consumed, nutrient composition, energy density, individual appetite regulatory hormones, and gastric distension.

Satiation plays a crucial role in regulating food intake and maintaining energy balance. Understanding the mechanisms underlying satiation can help individuals make healthier food choices and prevent overeating, thereby reducing the risk of obesity and other related health issues.

"Bombyx" is a genus name that refers to a group of insects in the family Bombycidae, which are known as silk moths. The most well-known species in this genus is "Bombyx mori," which is the domesticated silkworm used for commercial silk production.

The term "Bombyx" itself does not have a specific medical definition, but it is sometimes used in medical or scientific contexts to refer to this group of insects or their characteristics. For example, researchers might study the effects of Bombyx mori silk on wound healing or tissue regeneration.

It's worth noting that while some species of moths and butterflies can be harmful to human health in certain circumstances (such as by acting as vectors for diseases), the Bombyx genus is not typically considered a medical concern.

"Mesocricetus" is a genus of rodents, more commonly known as hamsters. It includes several species of hamsters that are native to various parts of Europe and Asia. The best-known member of this genus is the Syrian hamster, also known as the golden hamster or Mesocricetus auratus, which is a popular pet due to its small size and relatively easy care. These hamsters are burrowing animals and are typically solitary in the wild.

Linoleic acid is an essential polyunsaturated fatty acid, specifically an omega-6 fatty acid. It is called "essential" because our bodies cannot produce it; therefore, it must be obtained through our diet. Linoleic acid is a crucial component of cell membranes and is involved in the production of prostaglandins, which are hormone-like substances that regulate various bodily functions such as inflammation, blood pressure, and muscle contraction.

Foods rich in linoleic acid include vegetable oils (such as soybean, corn, and sunflower oil), nuts, seeds, and some fruits and vegetables. It is important to maintain a balance between omega-6 and omega-3 fatty acids in the diet, as excessive consumption of omega-6 fatty acids can contribute to inflammation and other health issues.

The reticular formation is not a single structure but rather a complex network of interconnected neurons located in the brainstem, extending from the medulla oblongata through the pons and mesencephalon (midbrain) up to the diencephalon (thalamus and hypothalamus). It forms part of the reticular activating system, which is involved in regulating arousal, awareness, and sleep-wake cycles.

The reticular formation plays a crucial role in various functions such as:

1. Modulation of sensory input: The neurons in the reticular formation receive inputs from all senses (visual, auditory, tactile, etc.) and help filter and prioritize this information before it reaches higher cognitive areas.

2. Control of motor function: The reticular formation contributes to the regulation of muscle tone, posture, and locomotion by modulating the activity of motor neurons in the spinal cord.

3. Regulation of autonomic functions: The reticular formation is involved in controlling heart rate, blood pressure, respiration, and other visceral functions through its connections with the autonomic nervous system.

4. Consciousness and arousal: The ascending reticular activating system (ARAS) originates from the reticular formation and projects to the thalamus and cerebral cortex, where it helps maintain wakefulness and arousal. Damage to the ARAS can lead to coma or other states of altered consciousness.

5. Sleep-wake cycle regulation: The reticular formation contains cells that release neurotransmitters like histamine, serotonin, and orexin/hypocretin, which are essential for sleep-wake regulation. Dysfunction in these circuits has been implicated in various sleep disorders, such as narcolepsy and insomnia.

The medulla oblongata is a part of the brainstem that is located in the posterior portion of the brainstem and continues with the spinal cord. It plays a vital role in controlling several critical bodily functions, such as breathing, heart rate, and blood pressure. The medulla oblongata also contains nerve pathways that transmit sensory information from the body to the brain and motor commands from the brain to the muscles. Additionally, it is responsible for reflexes such as vomiting, swallowing, coughing, and sneezing.

G-Protein-Coupled Receptor Kinase 2 (GRK2) is a serine/threonine protein kinase that plays a crucial role in the regulation of G-protein-coupled receptors (GPCRs). GRK2 phosphorylates activated GPCRs, which promotes the binding of arrestin proteins and leads to the desensitization and internalization of the receptor. This process helps to fine-tune the signaling responses mediated by GPCRs and is important for maintaining normal cellular function.

GRK2 is widely expressed in various tissues, including the heart, brain, and lungs, and has been implicated in several physiological processes, such as cardiac contractility, neurotransmission, and inflammation. Dysregulation of GRK2 activity has been associated with several diseases, including heart failure, cancer, and neurological disorders. Therefore, GRK2 is an important target for the development of therapeutic strategies aimed at modulating GPCR signaling in various disease contexts.

The prosencephalon is a term used in the field of neuroembryology, which refers to the developmental stage of the forebrain in the embryonic nervous system. It is one of the three primary vesicles that form during the initial stages of neurulation, along with the mesencephalon (midbrain) and rhombencephalon (hindbrain).

The prosencephalon further differentiates into two secondary vesicles: the telencephalon and diencephalon. The telencephalon gives rise to structures such as the cerebral cortex, basal ganglia, and olfactory bulbs, while the diencephalon develops into structures like the thalamus, hypothalamus, and epithalamus.

It is important to note that 'prosencephalon' itself is not used as a medical term in adult neuroanatomy, but it is crucial for understanding the development of the human brain during embryogenesis.

"Butterflies" is not a medical term, but rather a colloquial or informal term that is often used to describe a feeling of nervousness or excitement in the stomach. It is thought to be due to the release of adrenaline and the increased heart rate and breathing that can occur when someone is anxious or excited. The sensation may be caused by the contraction of the muscles in the stomach, which can feel like fluttering or flips. This feeling is not a medical condition and does not typically require treatment, but if it is severe or persistent, it may be helpful to speak with a healthcare provider to address any underlying anxiety or stress.

A microelectrode is a small electrode with dimensions ranging from several micrometers to a few tens of micrometers in diameter. They are used in various biomedical applications, such as neurophysiological studies, neuromodulation, and brain-computer interfaces. In these applications, microelectrodes serve to record electrical activity from individual or small groups of neurons or deliver electrical stimuli to specific neural structures with high spatial resolution.

Microelectrodes can be fabricated using various materials, including metals (e.g., tungsten, stainless steel, platinum), metal alloys, carbon fibers, and semiconductor materials like silicon. The design of microelectrodes may vary depending on the specific application, with some common types being sharpened metal wires, glass-insulated metal microwires, and silicon-based probes with multiple recording sites.

The development and use of microelectrodes have significantly contributed to our understanding of neural function in health and disease, enabling researchers and clinicians to investigate the underlying mechanisms of neurological disorders and develop novel therapies for conditions such as Parkinson's disease, epilepsy, and hearing loss.

The thalamus is a large, paired structure in the brain that serves as a relay station for sensory and motor signals to the cerebral cortex. It is located in the dorsal part of the diencephalon and is made up of two symmetrical halves, each connected to the corresponding cerebral hemisphere.

The thalamus receives inputs from almost all senses, except for the olfactory system, and processes them before sending them to specific areas in the cortex. It also plays a role in regulating consciousness, sleep, and alertness. Additionally, the thalamus is involved in motor control by relaying information between the cerebellum and the motor cortex.

The thalamus is divided into several nuclei, each with distinct connections and functions. Some of these nuclei are involved in sensory processing, while others are involved in motor function or regulation of emotions and cognition. Overall, the thalamus plays a critical role in integrating information from various brain regions and modulating cognitive and emotional processes.

The limbic system is a complex set of structures in the brain that includes the hippocampus, amygdala, fornix, cingulate gyrus, and other nearby areas. It's associated with emotional responses, instinctual behaviors, motivation, long-term memory formation, and olfaction (smell). The limbic system is also involved in the modulation of visceral functions and drives, such as hunger, thirst, and sexual drive.

The structures within the limbic system communicate with each other and with other parts of the brain, particularly the hypothalamus and the cortex, to regulate various physiological and psychological processes. Dysfunctions in the limbic system can lead to a range of neurological and psychiatric conditions, including depression, anxiety disorders, post-traumatic stress disorder (PTSD), and certain types of memory impairment.

"Macaca fascicularis" is the scientific name for the crab-eating macaque, also known as the long-tailed macaque. It's a species of monkey that is native to Southeast Asia. They are called "crab-eating" macaques because they are known to eat crabs and other crustaceans. These monkeys are omnivorous and their diet also includes fruits, seeds, insects, and occasionally smaller vertebrates.

Crab-eating macaques are highly adaptable and can be found in a wide range of habitats, including forests, grasslands, and wetlands. They are also known to live in close proximity to human settlements and are often considered pests due to their tendency to raid crops and steal food from humans.

These monkeys are social animals and live in large groups called troops. They have a complex social structure with a clear hierarchy and dominant males. Crab-eating macaques are also known for their intelligence and problem-solving abilities.

In medical research, crab-eating macaques are often used as animal models due to their close genetic relationship to humans. They are used in studies related to infectious diseases, neuroscience, and reproductive biology, among others.

Choice behavior refers to the selection or decision-making process in which an individual consciously or unconsciously chooses one option over others based on their preferences, values, experiences, and motivations. In a medical context, choice behavior may relate to patients' decisions about their healthcare, such as selecting a treatment option, choosing a healthcare provider, or adhering to a prescribed medication regimen. Understanding choice behavior is essential in shaping health policies, developing patient-centered care models, and improving overall health outcomes.

In medical terms, sensation refers to the ability to perceive and interpret various stimuli from our environment through specialized receptor cells located throughout the body. These receptors convert physical stimuli such as light, sound, temperature, pressure, and chemicals into electrical signals that are transmitted to the brain via nerves. The brain then interprets these signals, allowing us to experience sensations like sight, hearing, touch, taste, and smell.

There are two main types of sensations: exteroceptive and interoceptive. Exteroceptive sensations involve stimuli from outside the body, such as light, sound, and touch. Interoceptive sensations, on the other hand, refer to the perception of internal bodily sensations, such as hunger, thirst, heartbeat, or emotions.

Disorders in sensation can result from damage to the nervous system, including peripheral nerves, spinal cord, or brain. Examples include numbness, tingling, pain, or loss of sensation in specific body parts, which can significantly impact a person's quality of life and ability to perform daily activities.

Developmental gene expression regulation refers to the processes that control the activation or repression of specific genes during embryonic and fetal development. These regulatory mechanisms ensure that genes are expressed at the right time, in the right cells, and at appropriate levels to guide proper growth, differentiation, and morphogenesis of an organism.

Developmental gene expression regulation is a complex and dynamic process involving various molecular players, such as transcription factors, chromatin modifiers, non-coding RNAs, and signaling molecules. These regulators can interact with cis-regulatory elements, like enhancers and promoters, to fine-tune the spatiotemporal patterns of gene expression during development.

Dysregulation of developmental gene expression can lead to various congenital disorders and developmental abnormalities. Therefore, understanding the principles and mechanisms governing developmental gene expression regulation is crucial for uncovering the etiology of developmental diseases and devising potential therapeutic strategies.

Caffeine is a central nervous system stimulant that occurs naturally in the leaves, seeds, or fruits of some plants. It can also be produced artificially and added to various products, such as food, drinks, and medications. Caffeine has a number of effects on the body, including increasing alertness, improving mood, and boosting energy levels.

In small doses, caffeine is generally considered safe for most people. However, consuming large amounts of caffeine can lead to negative side effects, such as restlessness, insomnia, rapid heart rate, and increased blood pressure. It is also possible to become dependent on caffeine, and withdrawal symptoms can occur if consumption is suddenly stopped.

Caffeine is found in a variety of products, including coffee, tea, chocolate, energy drinks, and some medications. The amount of caffeine in these products can vary widely, so it is important to pay attention to serving sizes and labels to avoid consuming too much.

Acetic acid is an organic compound with the chemical formula CH3COOH. It is a colorless liquid with a pungent, vinegar-like smell and is the main component of vinegar. In medical terms, acetic acid is used as a topical antiseptic and antibacterial agent, particularly for the treatment of ear infections, external genital warts, and nail fungus. It can also be used as a preservative and solvent in some pharmaceutical preparations.

Sodium chloride, commonly known as salt, is an essential electrolyte in dietary intake. It is a chemical compound made up of sodium (Na+) and chloride (Cl-) ions. In a medical context, particularly in nutrition and dietetics, "sodium chloride, dietary" refers to the consumption of this compound in food sources.

Sodium plays a crucial role in various bodily functions such as maintaining fluid balance, assisting nerve impulse transmission, and contributing to muscle contraction. The Dietary Guidelines for Americans recommend limiting sodium intake to less than 2,300 milligrams (mg) per day and further suggest an ideal limit of no more than 1,500 mg per day for most adults, especially those with high blood pressure. However, the average American consumes more than twice the recommended amount, primarily from processed and prepared foods. Excessive sodium intake can lead to high blood pressure and increase the risk of heart disease and stroke.

Phylogeny is the evolutionary history and relationship among biological entities, such as species or genes, based on their shared characteristics. In other words, it refers to the branching pattern of evolution that shows how various organisms have descended from a common ancestor over time. Phylogenetic analysis involves constructing a tree-like diagram called a phylogenetic tree, which depicts the inferred evolutionary relationships among organisms or genes based on molecular sequence data or other types of characters. This information is crucial for understanding the diversity and distribution of life on Earth, as well as for studying the emergence and spread of diseases.

Proto-oncogene proteins, such as c-Fos, are normal cellular proteins that play crucial roles in various biological processes including cell growth, differentiation, and survival. They can be activated or overexpressed due to genetic alterations, leading to the formation of cancerous cells. The c-Fos protein is a nuclear phosphoprotein involved in signal transduction pathways and forms a heterodimer with c-Jun to create the activator protein-1 (AP-1) transcription factor complex. This complex binds to specific DNA sequences, thereby regulating the expression of target genes that contribute to various cellular responses, including proliferation, differentiation, and apoptosis. Dysregulation of c-Fos can result in uncontrolled cell growth and malignant transformation, contributing to tumor development and progression.

A medical definition of 'food' would be:

"Substances consumed by living organisms, usually in the form of meals, which contain necessary nutrients such as carbohydrates, proteins, fats, vitamins, minerals, and water. These substances are broken down during digestion to provide energy, build and repair tissues, and regulate bodily functions."

It's important to note that while this is a medical definition, it also aligns with common understanding of what food is.

Reaction time, in the context of medicine and physiology, refers to the time period between the presentation of a stimulus and the subsequent initiation of a response. This complex process involves the central nervous system, particularly the brain, which perceives the stimulus, processes it, and then sends signals to the appropriate muscles or glands to react.

There are different types of reaction times, including simple reaction time (responding to a single, expected stimulus) and choice reaction time (choosing an appropriate response from multiple possibilities). These measures can be used in clinical settings to assess various aspects of neurological function, such as cognitive processing speed, motor control, and alertness.

However, it is important to note that reaction times can be influenced by several factors, including age, fatigue, attention, and the use of certain medications or substances.

Magnetoencephalography (MEG) is a non-invasive functional neuroimaging technique used to measure the magnetic fields produced by electrical activity in the brain. These magnetic fields are detected by very sensitive devices called superconducting quantum interference devices (SQUIDs), which are cooled to extremely low temperatures to enhance their sensitivity. MEG provides direct and real-time measurement of neural electrical activity with high temporal resolution, typically on the order of milliseconds, allowing for the investigation of brain function during various cognitive, sensory, and motor tasks. It is often used in conjunction with other neuroimaging techniques, such as fMRI, to provide complementary information about brain structure and function.

A multigene family is a group of genetically related genes that share a common ancestry and have similar sequences or structures. These genes are arranged in clusters on a chromosome and often encode proteins with similar functions. They can arise through various mechanisms, including gene duplication, recombination, and transposition. Multigene families play crucial roles in many biological processes, such as development, immunity, and metabolism. Examples of multigene families include the globin genes involved in oxygen transport, the immune system's major histocompatibility complex (MHC) genes, and the cytochrome P450 genes associated with drug metabolism.

Biological metamorphosis is a complex process of transformation that certain organisms undergo during their development from embryo to adult. This process involves profound changes in form, function, and structure of the organism, often including modifications of various body parts, reorganization of internal organs, and changes in physiology.

In metamorphosis, a larval or juvenile form of an animal is significantly different from its adult form, both morphologically and behaviorally. This phenomenon is particularly common in insects, amphibians, and some fish and crustaceans. The most well-known examples include the transformation of a caterpillar into a butterfly or a tadpole into a frog.

The mechanisms that drive metamorphosis are regulated by hormonal signals and genetic programs. In many cases, metamorphosis is triggered by environmental factors such as temperature, moisture, or food availability, which interact with the organism's internal developmental cues to initiate the transformation. The process of metamorphosis allows these organisms to exploit different ecological niches at different stages of their lives and contributes to their evolutionary success.

Implanted electrodes are medical devices that are surgically placed inside the body to interface directly with nerves, neurons, or other electrically excitable tissue for various therapeutic purposes. These electrodes can be used to stimulate or record electrical activity from specific areas of the body, depending on their design and application.

There are several types of implanted electrodes, including:

1. Deep Brain Stimulation (DBS) electrodes: These are placed deep within the brain to treat movement disorders such as Parkinson's disease, essential tremor, and dystonia. DBS electrodes deliver electrical impulses that modulate abnormal neural activity in targeted brain regions.
2. Spinal Cord Stimulation (SCS) electrodes: These are implanted along the spinal cord to treat chronic pain syndromes. SCS electrodes emit low-level electrical pulses that interfere with pain signals traveling to the brain, providing relief for patients.
3. Cochlear Implant electrodes: These are surgically inserted into the cochlea of the inner ear to restore hearing in individuals with severe to profound hearing loss. The electrodes stimulate the auditory nerve directly, bypassing damaged hair cells within the cochlea.
4. Retinal Implant electrodes: These are implanted in the retina to treat certain forms of blindness caused by degenerative eye diseases like retinitis pigmentosa. The electrodes convert visual information from a camera into electrical signals, which stimulate remaining retinal cells and transmit the information to the brain via the optic nerve.
5. Sacral Nerve Stimulation (SNS) electrodes: These are placed near the sacral nerves in the lower back to treat urinary or fecal incontinence and overactive bladder syndrome. SNS electrodes deliver electrical impulses that regulate the function of the affected muscles and nerves.
6. Vagus Nerve Stimulation (VNS) electrodes: These are wrapped around the vagus nerve in the neck to treat epilepsy and depression. VNS electrodes provide intermittent electrical stimulation to the vagus nerve, which has connections to various regions of the brain involved in these conditions.

Overall, implanted electrodes serve as a crucial component in many neuromodulation therapies, offering an effective treatment option for numerous neurological and sensory disorders.

Olfactory receptor neurons (ORNs) are specialized sensory nerve cells located in the olfactory epithelium, a patch of tissue inside the nasal cavity. These neurons are responsible for detecting and transmitting information about odors to the brain. Each ORN expresses only one type of olfactory receptor protein, which is specific to certain types of odor molecules. When an odor molecule binds to its corresponding receptor, it triggers a signal transduction pathway that generates an electrical impulse in the neuron. This impulse is then transmitted to the brain via the olfactory nerve, where it is processed and interpreted as a specific smell. ORNs are continuously replaced throughout an individual's lifetime due to their exposure to environmental toxins and other damaging agents.

The gastrointestinal (GI) tract, also known as the digestive tract, is a continuous tube that starts at the mouth and ends at the anus. It is responsible for ingesting, digesting, absorbing, and excreting food and waste materials. The GI tract includes the mouth, esophagus, stomach, small intestine (duodenum, jejunum, ileum), large intestine (cecum, colon, rectum, anus), and accessory organs such as the liver, gallbladder, and pancreas. The primary function of this system is to process and extract nutrients from food while also protecting the body from harmful substances, pathogens, and toxins.

C57BL/6 (C57 Black 6) is an inbred strain of laboratory mouse that is widely used in biomedical research. The term "inbred" refers to a strain of animals where matings have been carried out between siblings or other closely related individuals for many generations, resulting in a population that is highly homozygous at most genetic loci.

The C57BL/6 strain was established in 1920 by crossing a female mouse from the dilute brown (DBA) strain with a male mouse from the black strain. The resulting offspring were then interbred for many generations to create the inbred C57BL/6 strain.

C57BL/6 mice are known for their robust health, longevity, and ease of handling, making them a popular choice for researchers. They have been used in a wide range of biomedical research areas, including studies of cancer, immunology, neuroscience, cardiovascular disease, and metabolism.

One of the most notable features of the C57BL/6 strain is its sensitivity to certain genetic modifications, such as the introduction of mutations that lead to obesity or impaired glucose tolerance. This has made it a valuable tool for studying the genetic basis of complex diseases and traits.

Overall, the C57BL/6 inbred mouse strain is an important model organism in biomedical research, providing a valuable resource for understanding the genetic and molecular mechanisms underlying human health and disease.

Discrimination learning is a type of learning in which an individual learns to distinguish between two or more stimuli and respond differently to each. It involves the ability to recognize the differences between similar stimuli and to respond appropriately based on the specific characteristics of each stimulus. This type of learning is important for many aspects of cognition, including perception, language, and problem-solving.

In discrimination learning, an individual may be presented with two or more stimuli and reinforced for responding differently to each. For example, a person might be trained to press a button in response to the color red and to do nothing in response to the color green. Through this process of differential reinforcement, the individual learns to discriminate between the two colors and to respond appropriately to each.

Discrimination learning is often studied in animals as well as humans, and it is thought to involve a range of cognitive processes, including attention, memory, and perception. It is an important aspect of many forms of learning and plays a role in a wide variety of behaviors.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

Excitatory amino acid agonists are substances that bind to and activate excitatory amino acid receptors, leading to an increase in the excitation or activation of neurons. The most common excitatory amino acids in the central nervous system are glutamate and aspartate.

Agonists of excitatory amino acid receptors can be divided into two main categories: ionotropic and metabotropic. Ionotropic receptors, such as N-methyl-D-aspartate (NMDA), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), and kainite receptors, are ligand-gated ion channels that directly mediate fast excitatory synaptic transmission. Metabotropic receptors, on the other hand, are G protein-coupled receptors that modulate synaptic activity through second messenger systems.

Excitatory amino acid agonists have been implicated in various physiological and pathophysiological processes, including learning and memory, neurodevelopment, and neurodegenerative disorders such as stroke, epilepsy, and Alzheimer's disease. They are also used in research to study the functions of excitatory amino acid receptors and their roles in neuronal signaling. However, due to their potential neurotoxic effects, the therapeutic use of excitatory amino acid agonists is limited.

A nerve net, also known as a neural net or neuronal network, is not a medical term per se, but rather a concept in neuroscience and artificial intelligence (AI). It refers to a complex network of interconnected neurons that process and transmit information. In the context of the human body, the nervous system can be thought of as a type of nerve net, with the brain and spinal cord serving as the central processing unit and peripheral nerves carrying signals to and from various parts of the body.

In the field of AI, artificial neural networks are computational models inspired by the structure and function of biological nerve nets. These models consist of interconnected nodes or "neurons" that process information and learn patterns through a process of training and adaptation. They have been used in a variety of applications, including image recognition, natural language processing, and machine learning.

Signal transduction is the process by which a cell converts an extracellular signal, such as a hormone or neurotransmitter, into an intracellular response. This involves a series of molecular events that transmit the signal from the cell surface to the interior of the cell, ultimately resulting in changes in gene expression, protein activity, or metabolism.

The process typically begins with the binding of the extracellular signal to a receptor located on the cell membrane. This binding event activates the receptor, which then triggers a cascade of intracellular signaling molecules, such as second messengers, protein kinases, and ion channels. These molecules amplify and propagate the signal, ultimately leading to the activation or inhibition of specific cellular responses.

Signal transduction pathways are highly regulated and can be modulated by various factors, including other signaling molecules, post-translational modifications, and feedback mechanisms. Dysregulation of these pathways has been implicated in a variety of diseases, including cancer, diabetes, and neurological disorders.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Fructose is a simple monosaccharide, also known as "fruit sugar." It is a naturally occurring carbohydrate that is found in fruits, vegetables, and honey. Fructose has the chemical formula C6H12O6 and is a hexose, or six-carbon sugar.

Fructose is absorbed directly into the bloodstream during digestion and is metabolized primarily in the liver. It is sweeter than other sugars such as glucose and sucrose (table sugar), which makes it a popular sweetener in many processed foods and beverages. However, consuming large amounts of fructose can have negative health effects, including increasing the risk of obesity, diabetes, and heart disease.

Confocal microscopy is a powerful imaging technique used in medical and biological research to obtain high-resolution, contrast-rich images of thick samples. This super-resolution technology provides detailed visualization of cellular structures and processes at various depths within a specimen.

In confocal microscopy, a laser beam focused through a pinhole illuminates a small spot within the sample. The emitted fluorescence or reflected light from this spot is then collected by a detector, passing through a second pinhole that ensures only light from the focal plane reaches the detector. This process eliminates out-of-focus light, resulting in sharp images with improved contrast compared to conventional widefield microscopy.

By scanning the laser beam across the sample in a raster pattern and collecting fluorescence at each point, confocal microscopy generates optical sections of the specimen. These sections can be combined to create three-dimensional reconstructions, allowing researchers to study cellular architecture and interactions within complex tissues.

Confocal microscopy has numerous applications in medical research, including studying protein localization, tracking intracellular dynamics, analyzing cell morphology, and investigating disease mechanisms at the cellular level. Additionally, it is widely used in clinical settings for diagnostic purposes, such as analyzing skin lesions or detecting pathogens in patient samples.

Sensory thresholds are the minimum levels of stimulation that are required to produce a sensation in an individual, as determined through psychophysical testing. These tests measure the point at which a person can just barely detect the presence of a stimulus, such as a sound, light, touch, or smell.

There are two types of sensory thresholds: absolute and difference. Absolute threshold is the minimum level of intensity required to detect a stimulus 50% of the time. Difference threshold, also known as just noticeable difference (JND), is the smallest change in intensity that can be detected between two stimuli.

Sensory thresholds can vary between individuals and are influenced by factors such as age, attention, motivation, and expectations. They are often used in clinical settings to assess sensory function and diagnose conditions such as hearing or vision loss.

Quaternary ammonium compounds (QACs) are a group of disinfectants and antiseptics that contain a nitrogen atom surrounded by four organic groups, resulting in a charged "quat" structure. They are widely used in healthcare settings due to their broad-spectrum activity against bacteria, viruses, fungi, and spores. QACs work by disrupting the cell membrane of microorganisms, leading to their death. Common examples include benzalkonium chloride and cetyltrimethylammonium bromide. It is important to note that some microorganisms have developed resistance to QACs, and they may not be effective against all types of pathogens.

Neuronal plasticity, also known as neuroplasticity or neural plasticity, refers to the ability of the brain and nervous system to change and adapt as a result of experience, learning, injury, or disease. This can involve changes in the structure, organization, and function of neurons (nerve cells) and their connections (synapses) in the central and peripheral nervous systems.

Neuronal plasticity can take many forms, including:

* Synaptic plasticity: Changes in the strength or efficiency of synaptic connections between neurons. This can involve the formation, elimination, or modification of synapses.
* Neural circuit plasticity: Changes in the organization and connectivity of neural circuits, which are networks of interconnected neurons that process information.
* Structural plasticity: Changes in the physical structure of neurons, such as the growth or retraction of dendrites (branches that receive input from other neurons) or axons (projections that transmit signals to other neurons).
* Functional plasticity: Changes in the physiological properties of neurons, such as their excitability, responsiveness, or sensitivity to stimuli.

Neuronal plasticity is a fundamental property of the nervous system and plays a crucial role in many aspects of brain function, including learning, memory, perception, and cognition. It also contributes to the brain's ability to recover from injury or disease, such as stroke or traumatic brain injury.

Classical conditioning is a type of learning process that occurs when two stimuli are repeatedly paired together, leading to an association between them. This concept was first introduced by Ivan Pavlov, a Russian physiologist, in his studies on classical conditioning in the late 19th and early 20th centuries.

In classical conditioning, there are typically two types of stimuli involved: the unconditioned stimulus (US) and the neutral stimulus (NS). The US is a stimulus that naturally triggers a response, known as the unconditioned response (UR), in an organism. For example, food is an US that triggers salivation, which is the UR, in dogs.

The NS, on the other hand, is a stimulus that does not initially trigger any response in the organism. However, when the NS is repeatedly paired with the US, it becomes a conditioned stimulus (CS) and begins to elicit a conditioned response (CR). The CR is similar to the UR but is triggered by the CS instead of the US.

For example, if Pavlov repeatedly rang a bell (NS) just before presenting food (US) to a dog, the dog would eventually start salivating (CR) in response to the bell (CS) even when food was not presented. This is an example of classical conditioning.

Classical conditioning has been widely studied and is believed to play a role in various physiological processes, such as learning, memory, and emotion regulation. It has also been used in various applications, including behavioral therapy and advertising.

Chemotaxis is a term used in biology and medicine to describe the movement of an organism or cell towards or away from a chemical stimulus. This process plays a crucial role in various biological phenomena, including immune responses, wound healing, and the development and progression of diseases such as cancer.

In chemotaxis, cells can detect and respond to changes in the concentration of specific chemicals, known as chemoattractants or chemorepellents, in their environment. These chemicals bind to receptors on the cell surface, triggering a series of intracellular signaling events that ultimately lead to changes in the cytoskeleton and directed movement of the cell towards or away from the chemical gradient.

For example, during an immune response, white blood cells called neutrophils use chemotaxis to migrate towards sites of infection or inflammation, where they can attack and destroy invading pathogens. Similarly, cancer cells can use chemotaxis to migrate towards blood vessels and metastasize to other parts of the body.

Understanding chemotaxis is important for developing new therapies and treatments for a variety of diseases, including cancer, infectious diseases, and inflammatory disorders.

Neurotransmitter agents are substances that affect the synthesis, storage, release, uptake, degradation, or reuptake of neurotransmitters, which are chemical messengers that transmit signals across a chemical synapse from one neuron to another. These agents can be either agonists, which mimic the action of a neurotransmitter and bind to its receptor, or antagonists, which block the action of a neurotransmitter by binding to its receptor without activating it. They are used in medicine to treat various neurological and psychiatric disorders, such as depression, anxiety, and Parkinson's disease.

Nerve tissue proteins are specialized proteins found in the nervous system that provide structural and functional support to nerve cells, also known as neurons. These proteins include:

1. Neurofilaments: These are type IV intermediate filaments that provide structural support to neurons and help maintain their shape and size. They are composed of three subunits - NFL (light), NFM (medium), and NFH (heavy).

2. Neuronal Cytoskeletal Proteins: These include tubulins, actins, and spectrins that provide structural support to the neuronal cytoskeleton and help maintain its integrity.

3. Neurotransmitter Receptors: These are specialized proteins located on the postsynaptic membrane of neurons that bind neurotransmitters released by presynaptic neurons, triggering a response in the target cell.

4. Ion Channels: These are transmembrane proteins that regulate the flow of ions across the neuronal membrane and play a crucial role in generating and transmitting electrical signals in neurons.

5. Signaling Proteins: These include enzymes, receptors, and adaptor proteins that mediate intracellular signaling pathways involved in neuronal development, differentiation, survival, and death.

6. Adhesion Proteins: These are cell surface proteins that mediate cell-cell and cell-matrix interactions, playing a crucial role in the formation and maintenance of neural circuits.

7. Extracellular Matrix Proteins: These include proteoglycans, laminins, and collagens that provide structural support to nerve tissue and regulate neuronal migration, differentiation, and survival.

A "knockout" mouse is a genetically engineered mouse in which one or more genes have been deleted or "knocked out" using molecular biology techniques. This allows researchers to study the function of specific genes and their role in various biological processes, as well as potential associations with human diseases. The mice are generated by introducing targeted DNA modifications into embryonic stem cells, which are then used to create a live animal. Knockout mice have been widely used in biomedical research to investigate gene function, disease mechanisms, and potential therapeutic targets.

Molecular sequence data refers to the specific arrangement of molecules, most commonly nucleotides in DNA or RNA, or amino acids in proteins, that make up a biological macromolecule. This data is generated through laboratory techniques such as sequencing, and provides information about the exact order of the constituent molecules. This data is crucial in various fields of biology, including genetics, evolution, and molecular biology, allowing for comparisons between different organisms, identification of genetic variations, and studies of gene function and regulation.

Cricetinae is a subfamily of rodents that includes hamsters, gerbils, and relatives. These small mammals are characterized by having short limbs, compact bodies, and cheek pouches for storing food. They are native to various parts of the world, particularly in Europe, Asia, and Africa. Some species are popular pets due to their small size, easy care, and friendly nature. In a medical context, understanding the biology and behavior of Cricetinae species can be important for individuals who keep them as pets or for researchers studying their physiology.

Nestin is a type of class VI intermediate filament protein that is primarily expressed in various types of undifferentiated or progenitor cells in the nervous system, including neural stem cells and progenitor cells. It is often used as a marker for these cells due to its expression during stages of active cell division and migration. Nestin is also expressed in some other tissues undergoing regeneration or injury.

Ion channels are specialized transmembrane proteins that form hydrophilic pores or gaps in the lipid bilayer of cell membranes. They regulate the movement of ions (such as sodium, potassium, calcium, and chloride) across the cell membrane by allowing these charged particles to pass through selectively in response to various stimuli, including voltage changes, ligand binding, mechanical stress, or temperature changes. This ion movement is essential for many physiological processes, including electrical signaling, neurotransmission, muscle contraction, and maintenance of resting membrane potential. Ion channels can be categorized based on their activation mechanisms, ion selectivity, and structural features. Dysfunction of ion channels can lead to various diseases, making them important targets for drug development.

Functional laterality, in a medical context, refers to the preferential use or performance of one side of the body over the other for specific functions. This is often demonstrated in hand dominance, where an individual may be right-handed or left-handed, meaning they primarily use their right or left hand for tasks such as writing, eating, or throwing.

However, functional laterality can also apply to other bodily functions and structures, including the eyes (ocular dominance), ears (auditory dominance), or legs. It's important to note that functional laterality is not a strict binary concept; some individuals may exhibit mixed dominance or no strong preference for one side over the other.

In clinical settings, assessing functional laterality can be useful in diagnosing and treating various neurological conditions, such as stroke or traumatic brain injury, where understanding any resulting lateralized impairments can inform rehabilitation strategies.

A mutation is a permanent change in the DNA sequence of an organism's genome. Mutations can occur spontaneously or be caused by environmental factors such as exposure to radiation, chemicals, or viruses. They may have various effects on the organism, ranging from benign to harmful, depending on where they occur and whether they alter the function of essential proteins. In some cases, mutations can increase an individual's susceptibility to certain diseases or disorders, while in others, they may confer a survival advantage. Mutations are the driving force behind evolution, as they introduce new genetic variability into populations, which can then be acted upon by natural selection.

Membrane potential is the electrical potential difference across a cell membrane, typically for excitable cells such as nerve and muscle cells. It is the difference in electric charge between the inside and outside of a cell, created by the selective permeability of the cell membrane to different ions. The resting membrane potential of a typical animal cell is around -70 mV, with the interior being negative relative to the exterior. This potential is generated and maintained by the active transport of ions across the membrane, primarily through the action of the sodium-potassium pump. Membrane potentials play a crucial role in many physiological processes, including the transmission of nerve impulses and the contraction of muscle cells.

Calcium is an essential mineral that is vital for various physiological processes in the human body. The medical definition of calcium is as follows:

Calcium (Ca2+) is a crucial cation and the most abundant mineral in the human body, with approximately 99% of it found in bones and teeth. It plays a vital role in maintaining structural integrity, nerve impulse transmission, muscle contraction, hormonal secretion, blood coagulation, and enzyme activation.

Calcium homeostasis is tightly regulated through the interplay of several hormones, including parathyroid hormone (PTH), calcitonin, and vitamin D. Dietary calcium intake, absorption, and excretion are also critical factors in maintaining optimal calcium levels in the body.

Hypocalcemia refers to low serum calcium levels, while hypercalcemia indicates high serum calcium levels. Both conditions can have detrimental effects on various organ systems and require medical intervention to correct.

Synaptic transmission is the process by which a neuron communicates with another cell, such as another neuron or a muscle cell, across a junction called a synapse. It involves the release of neurotransmitters from the presynaptic terminal of the neuron, which then cross the synaptic cleft and bind to receptors on the postsynaptic cell, leading to changes in the electrical or chemical properties of the target cell. This process is critical for the transmission of signals within the nervous system and for controlling various physiological functions in the body.

Capsaicin is defined in medical terms as the active component of chili peppers (genus Capsicum) that produces a burning sensation when it comes into contact with mucous membranes or skin. It is a potent irritant and is used topically as a counterirritant in some creams and patches to relieve pain. Capsaicin works by depleting substance P, a neurotransmitter that relays pain signals to the brain, from nerve endings.

Here is the medical definition of capsaicin from the Merriam-Webster's Medical Dictionary:

caпсаісіn : an alkaloid (C18H27NO3) that is the active principle of red peppers and is used in topical preparations as a counterirritant and analgesic.

Inositol is not considered a true "vitamin" because it can be created by the body from glucose. However, it is an important nutrient and is sometimes referred to as vitamin B8. It is a type of sugar alcohol that is found in both animals and plants. Inositol is involved in various biological processes, including:

1. Signal transduction: Inositol phospholipids are key components of cell membranes and play a crucial role in intracellular signaling pathways. They act as secondary messengers in response to hormones, neurotransmitters, and growth factors.
2. Insulin sensitivity: Inositol and its derivatives, such as myo-inositol and D-chiro-inositol, are involved in insulin signal transduction. Abnormalities in inositol metabolism have been linked to insulin resistance and conditions like polycystic ovary syndrome (PCOS).
3. Cerebral and ocular functions: Inositol is essential for the proper functioning of neurons and has been implicated in various neurological and psychiatric disorders, such as depression, anxiety, and bipolar disorder. It also plays a role in maintaining eye health.
4. Lipid metabolism: Inositol participates in the breakdown and transport of fats within the body.
5. Gene expression: Inositol and its derivatives are involved in regulating gene expression through epigenetic modifications.

Inositol can be found in various foods, including fruits, beans, grains, nuts, and vegetables. It is also available as a dietary supplement for those who wish to increase their intake.

Calcium signaling is the process by which cells regulate various functions through changes in intracellular calcium ion concentrations. Calcium ions (Ca^2+^) are crucial second messengers that play a critical role in many cellular processes, including muscle contraction, neurotransmitter release, gene expression, and programmed cell death (apoptosis).

Intracellular calcium levels are tightly regulated by a complex network of channels, pumps, and exchangers located on the plasma membrane and intracellular organelles such as the endoplasmic reticulum (ER) and mitochondria. These proteins control the influx, efflux, and storage of calcium ions within the cell.

Calcium signaling is initiated when an external signal, such as a hormone or neurotransmitter, binds to a specific receptor on the plasma membrane. This interaction triggers the opening of ion channels, allowing extracellular Ca^2+^ to flow into the cytoplasm. In some cases, this influx of calcium ions is sufficient to activate downstream targets directly. However, in most instances, the increase in intracellular Ca^2+^ serves as a trigger for the release of additional calcium from internal stores, such as the ER.

The release of calcium from the ER is mediated by ryanodine receptors (RyRs) and inositol trisphosphate receptors (IP3Rs), which are activated by specific second messengers generated in response to the initial external signal. The activation of these channels leads to a rapid increase in cytoplasmic Ca^2+^, creating a transient intracellular calcium signal known as a "calcium spark" or "calcium puff."

These localized increases in calcium concentration can then propagate throughout the cell as waves of elevated calcium, allowing for the spatial and temporal coordination of various cellular responses. The duration and amplitude of these calcium signals are finely tuned by the interplay between calcium-binding proteins, pumps, and exchangers, ensuring that appropriate responses are elicited in a controlled manner.

Dysregulation of intracellular calcium signaling has been implicated in numerous pathological conditions, including neurodegenerative diseases, cardiovascular disorders, and cancer. Therefore, understanding the molecular mechanisms governing calcium homeostasis and signaling is crucial for the development of novel therapeutic strategies targeting these diseases.

"Wistar rats" are a strain of albino rats that are widely used in laboratory research. They were developed at the Wistar Institute in Philadelphia, USA, and were first introduced in 1906. Wistar rats are outbred, which means that they are genetically diverse and do not have a fixed set of genetic characteristics like inbred strains.

Wistar rats are commonly used as animal models in biomedical research because of their size, ease of handling, and relatively low cost. They are used in a wide range of research areas, including toxicology, pharmacology, nutrition, cancer, cardiovascular disease, and behavioral studies. Wistar rats are also used in safety testing of drugs, medical devices, and other products.

Wistar rats are typically larger than many other rat strains, with males weighing between 500-700 grams and females weighing between 250-350 grams. They have a lifespan of approximately 2-3 years. Wistar rats are also known for their docile and friendly nature, making them easy to handle and work with in the laboratory setting.

The frontal lobe is the largest lobes of the human brain, located at the front part of each cerebral hemisphere and situated in front of the parietal and temporal lobes. It plays a crucial role in higher cognitive functions such as decision making, problem solving, planning, parts of social behavior, emotional expressions, physical reactions, and motor function. The frontal lobe is also responsible for what's known as "executive functions," which include the ability to focus attention, understand rules, switch focus, plan actions, and inhibit inappropriate behaviors. It is divided into five areas, each with its own specific functions: the primary motor cortex, premotor cortex, Broca's area, prefrontal cortex, and orbitofrontal cortex. Damage to the frontal lobe can result in a wide range of impairments, depending on the location and extent of the injury.

Wakefulness is a state of consciousness in which an individual is alert and aware of their surroundings. It is characterized by the ability to perceive, process, and respond to stimuli in a purposeful manner. In a medical context, wakefulness is often assessed using measures such as the electroencephalogram (EEG) to evaluate brain activity patterns associated with consciousness.

Wakefulness is regulated by several interconnected neural networks that promote arousal and attention. These networks include the ascending reticular activating system (ARAS), which consists of a group of neurons located in the brainstem that project to the thalamus and cerebral cortex, as well as other regions involved in regulating arousal and attention, such as the basal forebrain and hypothalamus.

Disorders of wakefulness can result from various underlying conditions, including neurological disorders, sleep disorders, medication side effects, or other medical conditions that affect brain function. Examples of such disorders include narcolepsy, insomnia, hypersomnia, and various forms of encephalopathy or brain injury.

Carbohydrate metabolism is the process by which the body breaks down carbohydrates into glucose, which is then used for energy or stored in the liver and muscles as glycogen. This process involves several enzymes and chemical reactions that convert carbohydrates from food into glucose, fructose, or galactose, which are then absorbed into the bloodstream and transported to cells throughout the body.

The hormones insulin and glucagon regulate carbohydrate metabolism by controlling the uptake and storage of glucose in cells. Insulin is released from the pancreas when blood sugar levels are high, such as after a meal, and promotes the uptake and storage of glucose in cells. Glucagon, on the other hand, is released when blood sugar levels are low and signals the liver to convert stored glycogen back into glucose and release it into the bloodstream.

Disorders of carbohydrate metabolism can result from genetic defects or acquired conditions that affect the enzymes or hormones involved in this process. Examples include diabetes, hypoglycemia, and galactosemia. Proper management of these disorders typically involves dietary modifications, medication, and regular monitoring of blood sugar levels.

In the context of medicine and healthcare, learning is often discussed in relation to learning abilities or disabilities that may impact an individual's capacity to acquire, process, retain, and apply new information or skills. Learning can be defined as the process of acquiring knowledge, understanding, behaviors, and skills through experience, instruction, or observation.

Learning disorders, also known as learning disabilities, are a type of neurodevelopmental disorder that affects an individual's ability to learn and process information in one or more areas, such as reading, writing, mathematics, or reasoning. These disorders are not related to intelligence or motivation but rather result from differences in the way the brain processes information.

It is important to note that learning can also be influenced by various factors, including age, cognitive abilities, physical and mental health status, cultural background, and educational experiences. Therefore, a comprehensive assessment of an individual's learning abilities and needs should take into account these various factors to provide appropriate support and interventions.

A transgene is a segment of DNA that has been artificially transferred from one organism to another, typically between different species, to introduce a new trait or characteristic. The term "transgene" specifically refers to the genetic material that has been transferred and has become integrated into the host organism's genome. This technology is often used in genetic engineering and biomedical research, including the development of genetically modified organisms (GMOs) for agricultural purposes or the creation of animal models for studying human diseases.

Transgenes can be created using various techniques, such as molecular cloning, where a desired gene is isolated, manipulated, and then inserted into a vector (a small DNA molecule, such as a plasmid) that can efficiently enter the host organism's cells. Once inside the cell, the transgene can integrate into the host genome, allowing for the expression of the new trait in the resulting transgenic organism.

It is important to note that while transgenes can provide valuable insights and benefits in research and agriculture, their use and release into the environment are subjects of ongoing debate due to concerns about potential ecological impacts and human health risks.

Species specificity is a term used in the field of biology, including medicine, to refer to the characteristic of a biological entity (such as a virus, bacterium, or other microorganism) that allows it to interact exclusively or preferentially with a particular species. This means that the biological entity has a strong affinity for, or is only able to infect, a specific host species.

For example, HIV is specifically adapted to infect human cells and does not typically infect other animal species. Similarly, some bacterial toxins are species-specific and can only affect certain types of animals or humans. This concept is important in understanding the transmission dynamics and host range of various pathogens, as well as in developing targeted therapies and vaccines.

Neural inhibition is a process in the nervous system that decreases or prevents the activity of neurons (nerve cells) in order to regulate and control communication within the nervous system. It is a fundamental mechanism that allows for the balance of excitation and inhibition necessary for normal neural function. Inhibitory neurotransmitters, such as GABA (gamma-aminobutyric acid) and glycine, are released from the presynaptic neuron and bind to receptors on the postsynaptic neuron, reducing its likelihood of firing an action potential. This results in a decrease in neural activity and can have various effects depending on the specific neurons and brain regions involved. Neural inhibition is crucial for many functions including motor control, sensory processing, attention, memory, and emotional regulation.

"Newborn animals" refers to the very young offspring of animals that have recently been born. In medical terminology, newborns are often referred to as "neonates," and they are classified as such from birth until about 28 days of age. During this time period, newborn animals are particularly vulnerable and require close monitoring and care to ensure their survival and healthy development.

The specific needs of newborn animals can vary widely depending on the species, but generally, they require warmth, nutrition, hydration, and protection from harm. In many cases, newborns are unable to regulate their own body temperature or feed themselves, so they rely heavily on their mothers for care and support.

In medical settings, newborn animals may be examined and treated by veterinarians to ensure that they are healthy and receiving the care they need. This can include providing medical interventions such as feeding tubes, antibiotics, or other treatments as needed to address any health issues that arise. Overall, the care and support of newborn animals is an important aspect of animal medicine and conservation efforts.

In the context of medical and clinical neuroscience, memory is defined as the brain's ability to encode, store, retain, and recall information or experiences. Memory is a complex cognitive process that involves several interconnected regions of the brain and can be categorized into different types based on various factors such as duration and the nature of the information being remembered.

The major types of memory include:

1. Sensory memory: The shortest form of memory, responsible for holding incoming sensory information for a brief period (less than a second to several seconds) before it is either transferred to short-term memory or discarded.
2. Short-term memory (also called working memory): A temporary storage system that allows the brain to hold and manipulate information for approximately 20-30 seconds, although this duration can be extended through rehearsal strategies. Short-term memory has a limited capacity, typically thought to be around 7±2 items.
3. Long-term memory: The memory system responsible for storing large amounts of information over extended periods, ranging from minutes to a lifetime. Long-term memory has a much larger capacity compared to short-term memory and is divided into two main categories: explicit (declarative) memory and implicit (non-declarative) memory.

Explicit (declarative) memory can be further divided into episodic memory, which involves the recollection of specific events or episodes, including their temporal and spatial contexts, and semantic memory, which refers to the storage and retrieval of general knowledge, facts, concepts, and vocabulary, independent of personal experience or context.

Implicit (non-declarative) memory encompasses various forms of learning that do not require conscious awareness or intention, such as procedural memory (skills and habits), priming (facilitated processing of related stimuli), classical conditioning (associative learning), and habituation (reduced responsiveness to repeated stimuli).

Memory is a crucial aspect of human cognition and plays a significant role in various aspects of daily life, including learning, problem-solving, decision-making, social interactions, and personal identity. Memory dysfunction can result from various neurological and psychiatric conditions, such as dementia, Alzheimer's disease, stroke, traumatic brain injury, and depression.

Interneurons are a type of neuron that is located entirely within the central nervous system (CNS), including the brain and spinal cord. They are called "inter" neurons because they connect and communicate with other nearby neurons, forming complex networks within the CNS. Interneurons receive input from sensory neurons and/or other interneurons and then send output signals to motor neurons or other interneurons.

Interneurons are responsible for processing information and modulating neural circuits in the CNS. They can have either excitatory or inhibitory effects on their target neurons, depending on the type of neurotransmitters they release. Excitatory interneurons release neurotransmitters such as glutamate that increase the likelihood of an action potential in the postsynaptic neuron, while inhibitory interneurons release neurotransmitters such as GABA (gamma-aminobutyric acid) or glycine that decrease the likelihood of an action potential.

Interneurons are diverse and can be classified based on various criteria, including their morphology, electrophysiological properties, neurochemical characteristics, and connectivity patterns. They play crucial roles in many aspects of CNS function, such as sensory processing, motor control, cognition, and emotion regulation. Dysfunction or damage to interneurons has been implicated in various neurological and psychiatric disorders, including epilepsy, Parkinson's disease, schizophrenia, and autism spectrum disorder.

In the context of healthcare and medical psychology, motivation refers to the driving force behind an individual's goal-oriented behavior. It is the internal or external stimuli that initiate, direct, and sustain a person's actions towards achieving their desired outcomes. Motivation can be influenced by various factors such as biological needs, personal values, emotional states, and social contexts.

In clinical settings, healthcare professionals often assess patients' motivation to engage in treatment plans, adhere to medical recommendations, or make lifestyle changes necessary for improving their health status. Enhancing a patient's motivation can significantly impact their ability to manage chronic conditions, recover from illnesses, and maintain overall well-being. Various motivational interviewing techniques and interventions are employed by healthcare providers to foster intrinsic motivation and support patients in achieving their health goals.

Embryonic and fetal development is the process of growth and development that occurs from fertilization of the egg (conception) to birth. The terms "embryo" and "fetus" are used to describe different stages of this development:

* Embryonic development: This stage begins at fertilization and continues until the end of the 8th week of pregnancy. During this time, the fertilized egg (zygote) divides and forms a blastocyst, which implants in the uterus and begins to develop into a complex structure called an embryo. The embryo consists of three layers of cells that will eventually form all of the organs and tissues of the body. During this stage, the basic structures of the body, including the nervous system, heart, and gastrointestinal tract, begin to form.
* Fetal development: This stage begins at the end of the 8th week of pregnancy and continues until birth. During this time, the embryo is called a fetus, and it grows and develops rapidly. The organs and tissues that were formed during the embryonic stage continue to mature and become more complex. The fetus also begins to move and kick, and it can hear and respond to sounds from outside the womb.

Overall, embryonic and fetal development is a complex and highly regulated process that involves the coordinated growth and differentiation of cells and tissues. It is a critical period of development that lays the foundation for the health and well-being of the individual throughout their life.

A reflex is an automatic, involuntary and rapid response to a stimulus that occurs without conscious intention. In the context of physiology and neurology, it's a basic mechanism that involves the transmission of nerve impulses between neurons, resulting in a muscle contraction or glandular secretion.

Reflexes are important for maintaining homeostasis, protecting the body from harm, and coordinating movements. They can be tested clinically to assess the integrity of the nervous system, such as the knee-j jerk reflex, which tests the function of the L3-L4 spinal nerve roots and the sensitivity of the stretch reflex arc.

Physiological adaptation refers to the changes or modifications that occur in an organism's biological functions or structures as a result of environmental pressures or changes. These adaptations enable the organism to survive and reproduce more successfully in its environment. They can be short-term, such as the constriction of blood vessels in response to cold temperatures, or long-term, such as the evolution of longer limbs in animals that live in open environments.

In the context of human physiology, examples of physiological adaptation include:

1. Acclimatization: The process by which the body adjusts to changes in environmental conditions, such as altitude or temperature. For example, when a person moves to a high-altitude location, their body may produce more red blood cells to compensate for the lower oxygen levels, leading to improved oxygen delivery to tissues.

2. Exercise adaptation: Regular physical activity can lead to various physiological adaptations, such as increased muscle strength and endurance, enhanced cardiovascular function, and improved insulin sensitivity.

3. Hormonal adaptation: The body can adjust hormone levels in response to changes in the environment or internal conditions. For instance, during prolonged fasting, the body releases stress hormones like cortisol and adrenaline to help maintain energy levels and prevent muscle wasting.

4. Sensory adaptation: Our senses can adapt to different stimuli over time. For example, when we enter a dark room after being in bright sunlight, it takes some time for our eyes to adjust to the new light level. This process is known as dark adaptation.

5. Aging-related adaptations: As we age, various physiological changes occur that help us adapt to the changing environment and maintain homeostasis. These include changes in body composition, immune function, and cognitive abilities.

Green Fluorescent Protein (GFP) is not a medical term per se, but a scientific term used in the field of molecular biology. GFP is a protein that exhibits bright green fluorescence when exposed to light, particularly blue or ultraviolet light. It was originally discovered in the jellyfish Aequorea victoria.

In medical and biological research, scientists often use recombinant DNA technology to introduce the gene for GFP into other organisms, including bacteria, plants, and animals, including humans. This allows them to track the expression and localization of specific genes or proteins of interest in living cells, tissues, or even whole organisms.

The ability to visualize specific cellular structures or processes in real-time has proven invaluable for a wide range of research areas, from studying the development and function of organs and organ systems to understanding the mechanisms of diseases and the effects of therapeutic interventions.

The vagus nerve, also known as the 10th cranial nerve (CN X), is the longest of the cranial nerves and extends from the brainstem to the abdomen. It has both sensory and motor functions and plays a crucial role in regulating various bodily functions such as heart rate, digestion, respiratory rate, speech, and sweating, among others.

The vagus nerve is responsible for carrying sensory information from the internal organs to the brain, and it also sends motor signals from the brain to the muscles of the throat and voice box, as well as to the heart, lungs, and digestive tract. The vagus nerve helps regulate the body's involuntary responses, such as controlling heart rate and blood pressure, promoting relaxation, and reducing inflammation.

Dysfunction in the vagus nerve can lead to various medical conditions, including gastroparesis, chronic pain, and autonomic nervous system disorders. Vagus nerve stimulation (VNS) is a therapeutic intervention that involves delivering electrical impulses to the vagus nerve to treat conditions such as epilepsy, depression, and migraine headaches.

Organ specificity, in the context of immunology and toxicology, refers to the phenomenon where a substance (such as a drug or toxin) or an immune response primarily affects certain organs or tissues in the body. This can occur due to various reasons such as:

1. The presence of specific targets (like antigens in the case of an immune response or receptors in the case of drugs) that are more abundant in these organs.
2. The unique properties of certain cells or tissues that make them more susceptible to damage.
3. The way a substance is metabolized or cleared from the body, which can concentrate it in specific organs.

For example, in autoimmune diseases, organ specificity describes immune responses that are directed against antigens found only in certain organs, such as the thyroid gland in Hashimoto's disease. Similarly, some toxins or drugs may have a particular affinity for liver cells, leading to liver damage or specific drug interactions.

Patch-clamp techniques are a group of electrophysiological methods used to study ion channels and other electrical properties of cells. These techniques were developed by Erwin Neher and Bert Sakmann, who were awarded the Nobel Prize in Physiology or Medicine in 1991 for their work. The basic principle of patch-clamp techniques involves creating a high resistance seal between a glass micropipette and the cell membrane, allowing for the measurement of current flowing through individual ion channels or groups of channels.

There are several different configurations of patch-clamp techniques, including:

1. Cell-attached configuration: In this configuration, the micropipette is attached to the outer surface of the cell membrane, and the current flowing across a single ion channel can be measured. This configuration allows for the study of the properties of individual channels in their native environment.
2. Whole-cell configuration: Here, the micropipette breaks through the cell membrane, creating a low resistance electrical connection between the pipette and the inside of the cell. This configuration allows for the measurement of the total current flowing across all ion channels in the cell membrane.
3. Inside-out configuration: In this configuration, the micropipette is pulled away from the cell after establishing a seal, resulting in the exposure of the inner surface of the cell membrane to the solution in the pipette. This configuration allows for the study of the properties of ion channels in isolation from other cellular components.
4. Outside-out configuration: Here, the micropipette is pulled away from the cell after establishing a seal, resulting in the exposure of the outer surface of the cell membrane to the solution in the pipette. This configuration allows for the study of the properties of ion channels in their native environment, but with the ability to control the composition of the extracellular solution.

Patch-clamp techniques have been instrumental in advancing our understanding of ion channel function and have contributed to numerous breakthroughs in neuroscience, pharmacology, and physiology.

Molecular evolution is the process of change in the DNA sequence or protein structure over time, driven by mechanisms such as mutation, genetic drift, gene flow, and natural selection. It refers to the evolutionary study of changes in DNA, RNA, and proteins, and how these changes accumulate and lead to new species and diversity of life. Molecular evolution can be used to understand the history and relationships among different organisms, as well as the functional consequences of genetic changes.

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors are ligand-gated ion channels found in the postsynaptic membrane of excitatory synapses in the central nervous system. They play a crucial role in fast synaptic transmission and are responsible for the majority of the fast excitatory postsynaptic currents (EPSCs) in the brain.

AMPA receptors are tetramers composed of four subunits, which can be any combination of GluA1-4 (previously known as GluR1-4). When the neurotransmitter glutamate binds to the AMPA receptor, it causes a conformational change that opens the ion channel, allowing the flow of sodium and potassium ions. This leads to depolarization of the postsynaptic membrane and the generation of an action potential if the depolarization is sufficient.

In addition to their role in synaptic transmission, AMPA receptors are also involved in synaptic plasticity, which is the ability of synapses to strengthen or weaken over time in response to changes in activity. This process is thought to underlie learning and memory.

In situ hybridization (ISH) is a molecular biology technique used to detect and localize specific nucleic acid sequences, such as DNA or RNA, within cells or tissues. This technique involves the use of a labeled probe that is complementary to the target nucleic acid sequence. The probe can be labeled with various types of markers, including radioisotopes, fluorescent dyes, or enzymes.

During the ISH procedure, the labeled probe is hybridized to the target nucleic acid sequence in situ, meaning that the hybridization occurs within the intact cells or tissues. After washing away unbound probe, the location of the labeled probe can be visualized using various methods depending on the type of label used.

In situ hybridization has a wide range of applications in both research and diagnostic settings, including the detection of gene expression patterns, identification of viral infections, and diagnosis of genetic disorders.

Guanylate cyclase is an enzyme that catalyzes the conversion of guanosine triphosphate (GTP) to cyclic guanosine monophosphate (cGMP), which acts as a second messenger in various cellular signaling pathways. There are two main types of guanylate cyclases: soluble and membrane-bound. Soluble guanylate cyclase is activated by nitric oxide, while membrane-bound guanylate cyclase can be activated by natriuretic peptides. The increased levels of cGMP produced by guanylate cyclase can lead to a variety of cellular responses, including smooth muscle relaxation, neurotransmitter release, and regulation of ion channels. Dysregulation of guanylate cyclase activity has been implicated in several diseases, such as hypertension, heart failure, and cancer.

Cyclic guanosine monophosphate (cGMP) is a important second messenger molecule that plays a crucial role in various biological processes within the human body. It is synthesized from guanosine triphosphate (GTP) by the enzyme guanylyl cyclase.

Cyclic GMP is involved in regulating diverse physiological functions, such as smooth muscle relaxation, cardiovascular function, and neurotransmission. It also plays a role in modulating immune responses and cellular growth and differentiation.

In the medical field, changes in cGMP levels or dysregulation of cGMP-dependent pathways have been implicated in various disease states, including pulmonary hypertension, heart failure, erectile dysfunction, and glaucoma. Therefore, pharmacological agents that target cGMP signaling are being developed as potential therapeutic options for these conditions.

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter that is found primarily in the gastrointestinal (GI) tract, blood platelets, and the central nervous system (CNS) of humans and other animals. It is produced by the conversion of the amino acid tryptophan to 5-hydroxytryptophan (5-HTP), and then to serotonin.

In the CNS, serotonin plays a role in regulating mood, appetite, sleep, memory, learning, and behavior, among other functions. It also acts as a vasoconstrictor, helping to regulate blood flow and blood pressure. In the GI tract, it is involved in peristalsis, the contraction and relaxation of muscles that moves food through the digestive system.

Serotonin is synthesized and stored in serotonergic neurons, which are nerve cells that use serotonin as their primary neurotransmitter. These neurons are found throughout the brain and spinal cord, and they communicate with other neurons by releasing serotonin into the synapse, the small gap between two neurons.

Abnormal levels of serotonin have been linked to a variety of disorders, including depression, anxiety, schizophrenia, and migraines. Medications that affect serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs), are commonly used to treat these conditions.

In a medical context, "hot temperature" is not a standard medical term with a specific definition. However, it is often used in relation to fever, which is a common symptom of illness. A fever is typically defined as a body temperature that is higher than normal, usually above 38°C (100.4°F) for adults and above 37.5-38°C (99.5-101.3°F) for children, depending on the source.

Therefore, when a medical professional talks about "hot temperature," they may be referring to a body temperature that is higher than normal due to fever or other causes. It's important to note that a high environmental temperature can also contribute to an elevated body temperature, so it's essential to consider both the body temperature and the environmental temperature when assessing a patient's condition.

Molecular biology is a branch of biology that deals with the structure, function, and organization of molecules involved in biological processes, especially informational molecules such as DNA, RNA, and proteins. It includes the study of molecular mechanisms of genetic inheritance, gene expression, protein synthesis, and cellular regulation. Molecular biology also involves the use of various experimental techniques to investigate and manipulate these molecules, including recombinant DNA technology, genomic sequencing, protein crystallography, and bioinformatics. The ultimate goal of molecular biology is to understand how biological systems work at a fundamental level and to apply this knowledge to improve human health and the environment.

"Sex characteristics" refer to the anatomical, chromosomal, and genetic features that define males and females. These include both primary sex characteristics (such as reproductive organs like ovaries or testes) and secondary sex characteristics (such as breasts or facial hair) that typically develop during puberty. Sex characteristics are primarily determined by the presence of either X or Y chromosomes, with XX individuals usually developing as females and XY individuals usually developing as males, although variations and exceptions to this rule do occur.

Glutamic acid is an alpha-amino acid, which is one of the 20 standard amino acids in the genetic code. The systematic name for this amino acid is (2S)-2-Aminopentanedioic acid. Its chemical formula is HO2CCH(NH2)CH2CH2CO2H.

Glutamic acid is a crucial excitatory neurotransmitter in the human brain, and it plays an essential role in learning and memory. It's also involved in the metabolism of sugars and amino acids, the synthesis of proteins, and the removal of waste nitrogen from the body.

Glutamic acid can be found in various foods such as meat, fish, beans, eggs, dairy products, and vegetables. In the human body, glutamic acid can be converted into gamma-aminobutyric acid (GABA), another important neurotransmitter that has a calming effect on the nervous system.

The hypothalamus is a small, vital region of the brain that lies just below the thalamus and forms part of the limbic system. It plays a crucial role in many important functions including:

1. Regulation of body temperature, hunger, thirst, fatigue, sleep, and circadian rhythms.
2. Production and regulation of hormones through its connection with the pituitary gland (the hypophysis). It controls the release of various hormones by producing releasing and inhibiting factors that regulate the anterior pituitary's function.
3. Emotional responses, behavior, and memory formation through its connections with the limbic system structures like the amygdala and hippocampus.
4. Autonomic nervous system regulation, which controls involuntary physiological functions such as heart rate, blood pressure, and digestion.
5. Regulation of the immune system by interacting with the autonomic nervous system.

Damage to the hypothalamus can lead to various disorders like diabetes insipidus, growth hormone deficiency, altered temperature regulation, sleep disturbances, and emotional or behavioral changes.

Gene expression is the process by which the information encoded in a gene is used to synthesize a functional gene product, such as a protein or RNA molecule. This process involves several steps: transcription, RNA processing, and translation. During transcription, the genetic information in DNA is copied into a complementary RNA molecule, known as messenger RNA (mRNA). The mRNA then undergoes RNA processing, which includes adding a cap and tail to the mRNA and splicing out non-coding regions called introns. The resulting mature mRNA is then translated into a protein on ribosomes in the cytoplasm through the process of translation.

The regulation of gene expression is a complex and highly controlled process that allows cells to respond to changes in their environment, such as growth factors, hormones, and stress signals. This regulation can occur at various stages of gene expression, including transcriptional activation or repression, RNA processing, mRNA stability, and translation. Dysregulation of gene expression has been implicated in many diseases, including cancer, genetic disorders, and neurological conditions.

Computer-assisted image processing is a medical term that refers to the use of computer systems and specialized software to improve, analyze, and interpret medical images obtained through various imaging techniques such as X-ray, CT (computed tomography), MRI (magnetic resonance imaging), ultrasound, and others.

The process typically involves several steps, including image acquisition, enhancement, segmentation, restoration, and analysis. Image processing algorithms can be used to enhance the quality of medical images by adjusting contrast, brightness, and sharpness, as well as removing noise and artifacts that may interfere with accurate diagnosis. Segmentation techniques can be used to isolate specific regions or structures of interest within an image, allowing for more detailed analysis.

Computer-assisted image processing has numerous applications in medical imaging, including detection and characterization of lesions, tumors, and other abnormalities; assessment of organ function and morphology; and guidance of interventional procedures such as biopsies and surgeries. By automating and standardizing image analysis tasks, computer-assisted image processing can help to improve diagnostic accuracy, efficiency, and consistency, while reducing the potential for human error.

Nerve Growth Factors (NGFs) are a family of proteins that play an essential role in the growth, maintenance, and survival of certain neurons (nerve cells). They were first discovered by Rita Levi-Montalcini and Stanley Cohen in 1956. NGF is particularly crucial for the development and function of the peripheral nervous system, which connects the central nervous system to various organs and tissues throughout the body.

NGF supports the differentiation and survival of sympathetic and sensory neurons during embryonic development. In adults, NGF continues to regulate the maintenance and repair of these neurons, contributing to neuroplasticity – the brain's ability to adapt and change over time. Additionally, NGF has been implicated in pain transmission and modulation, as well as inflammatory responses.

Abnormal levels or dysfunctional NGF signaling have been associated with various medical conditions, including neurodegenerative diseases (e.g., Alzheimer's and Parkinson's), chronic pain disorders, and certain cancers (e.g., small cell lung cancer). Therefore, understanding the role of NGF in physiological and pathological processes may provide valuable insights into developing novel therapeutic strategies for these conditions.

Transgenic mice are genetically modified rodents that have incorporated foreign DNA (exogenous DNA) into their own genome. This is typically done through the use of recombinant DNA technology, where a specific gene or genetic sequence of interest is isolated and then introduced into the mouse embryo. The resulting transgenic mice can then express the protein encoded by the foreign gene, allowing researchers to study its function in a living organism.

The process of creating transgenic mice usually involves microinjecting the exogenous DNA into the pronucleus of a fertilized egg, which is then implanted into a surrogate mother. The offspring that result from this procedure are screened for the presence of the foreign DNA, and those that carry the desired genetic modification are used to establish a transgenic mouse line.

Transgenic mice have been widely used in biomedical research to model human diseases, study gene function, and test new therapies. They provide a valuable tool for understanding complex biological processes and developing new treatments for a variety of medical conditions.

The prefrontal cortex is the anterior (frontal) part of the frontal lobe in the brain, involved in higher-order cognitive processes such as planning complex cognitive behavior, personality expression, decision making, and moderating social behavior. It also plays a significant role in working memory and executive functions. The prefrontal cortex is divided into several subregions, each associated with specific cognitive and emotional functions. Damage to the prefrontal cortex can result in various impairments, including difficulties with planning, decision making, and social behavior regulation.

An axon is a long, slender extension of a neuron (a type of nerve cell) that conducts electrical impulses (nerve impulses) away from the cell body to target cells, such as other neurons or muscle cells. Axons can vary in length from a few micrometers to over a meter long and are typically surrounded by a myelin sheath, which helps to insulate and protect the axon and allows for faster transmission of nerve impulses.

Axons play a critical role in the functioning of the nervous system, as they provide the means by which neurons communicate with one another and with other cells in the body. Damage to axons can result in serious neurological problems, such as those seen in spinal cord injuries or neurodegenerative diseases like multiple sclerosis.

Sodium channels are specialized protein structures that are embedded in the membranes of excitable cells, such as nerve and muscle cells. They play a crucial role in the generation and transmission of electrical signals in these cells. Sodium channels are responsible for the rapid influx of sodium ions into the cell during the initial phase of an action potential, which is the electrical signal that travels along the membrane of a neuron or muscle fiber. This sudden influx of sodium ions causes the membrane potential to rapidly reverse, leading to the depolarization of the cell. After the action potential, the sodium channels close and become inactivated, preventing further entry of sodium ions and helping to restore the resting membrane potential.

Sodium channels are composed of a large alpha subunit and one or two smaller beta subunits. The alpha subunit forms the ion-conducting pore, while the beta subunits play a role in modulating the function and stability of the channel. Mutations in sodium channel genes have been associated with various inherited diseases, including certain forms of epilepsy, cardiac arrhythmias, and muscle disorders.

Dietary fats, also known as fatty acids, are a major nutrient that the body needs for energy and various functions. They are an essential component of cell membranes and hormones, and they help the body absorb certain vitamins. There are several types of dietary fats:

1. Saturated fats: These are typically solid at room temperature and are found in animal products such as meat, butter, and cheese, as well as tropical oils like coconut and palm oil. Consuming a high amount of saturated fats can raise levels of unhealthy LDL cholesterol and increase the risk of heart disease.
2. Unsaturated fats: These are typically liquid at room temperature and can be further divided into monounsaturated and polyunsaturated fats. Monounsaturated fats, found in foods such as olive oil, avocados, and nuts, can help lower levels of unhealthy LDL cholesterol while maintaining levels of healthy HDL cholesterol. Polyunsaturated fats, found in foods such as fatty fish, flaxseeds, and walnuts, have similar effects on cholesterol levels and also provide essential omega-3 and omega-6 fatty acids that the body cannot produce on its own.
3. Trans fats: These are unsaturated fats that have been chemically modified to be solid at room temperature. They are often found in processed foods such as baked goods, fried foods, and snack foods. Consuming trans fats can raise levels of unhealthy LDL cholesterol and lower levels of healthy HDL cholesterol, increasing the risk of heart disease.

It is recommended to limit intake of saturated and trans fats and to consume more unsaturated fats as part of a healthy diet.

Messenger RNA (mRNA) is a type of RNA (ribonucleic acid) that carries genetic information copied from DNA in the form of a series of three-base code "words," each of which specifies a particular amino acid. This information is used by the cell's machinery to construct proteins, a process known as translation. After being transcribed from DNA, mRNA travels out of the nucleus to the ribosomes in the cytoplasm where protein synthesis occurs. Once the protein has been synthesized, the mRNA may be degraded and recycled. Post-transcriptional modifications can also occur to mRNA, such as alternative splicing and addition of a 5' cap and a poly(A) tail, which can affect its stability, localization, and translation efficiency.

... is excessive sweating classified under focal hyperhidrosis, that is, it is restricted to certain ... This type of sweating is known as Frey's syndrome. Gustatory hyperhidrosis has been observed in diabetics with autonomic ... Excessive sweating, hyperhidrosis causes". patient.info. Retrieved 30 January 2021. v t e (Articles with short description, ...
Gustatory sweating refers to thermal sweating induced by the ingestion of food. The increase in metabolism caused by ingestion ... Normally, only a certain number of sweat glands are actively producing sweat. When stimuli call for more sweating, more sweat ... Generally, sweat glands consist of a secretory unit that produces sweat, and a duct that carries the sweat away. The secretory ... The clear secretion produced by eccrine sweat glands is termed sweat or sensible perspiration. Sweat is mostly water, but it ...
Gustatory sweating or Frey's syndrome is another presentation of autonomic neuropathy. Gustatory sweating is brought on while ... Aberrant gustatory sweating follows up to 73% of surgical sympathectomies and is particularly common after bilateral procedures ... The sweating is induced to reduce body heat. Excessive sweating due to nervousness, anger, previous trauma or fear is called ... Phantom sweating is a sensation that one is sweating, while the skin remains dry. Affected people can not distinguish whether ...
Salivation leads to perspiration and flushing of the pre-auricular region and is called 'gustatory sweating'. Plan of the ... which innervate the parotid gland and sweat glands of the face respectively, form abnormal connections. ...
Understanding gustatory sweating. What have we learned from Lucja Frey and her predecessors?. Clinical autonomic research : ... All these observations lack a wide view of the anatomy, pathology and exact mechanism of gustatory sweating. Łucja Frey's ... Clinical cases V: a case of localized sweating. Transactions: Clinical Society of London 31: 277-280 (1897) As cited in Dunbar ...
He investigated the function of the sympathetic nervous system in the sweating conditions hyperhidrosis and gustatory ... suturing and investigated the function of the sympathetic nervous system in the sweating conditions hyperhidrosis and gustatory ...
Gustatory rhinitis - spicy and pungent food may in some people produce rhinorrhea, nasal stuffiness, lacrimation, sweating and ... Raphael G, Raphael MH, Kaliner M (January 1989). "Gustatory rhinitis: a syndrome of food-induced rhinorrhea". The Journal of ...
... "gustatory sweating" or sweating in the anticipation of eating, instead of the normal salivary response. It is often seen with ... Observing sweating in the region after eating a lemon wedge may be diagnostic. Signs and symptoms include erythema (redness or ... flushing) and sweating in the cutaneous distribution of the auriculotemporal nerve, usually in response to gustatory stimuli. ... The symptoms of Frey's syndrome are redness and sweating on the cheek area adjacent to the ear (see focal hyperhidrosis). They ...
His ability, often activated when stressed or angry, produces a mix of chemical "sweat" through his skin to convert into a ... See: visual, auditory, tactile, olfaction, gustatory, vestibular, and proprioception). She can view things at a microscopic ... She also appears to have the ability to detect when people are lying, by judging microexpressions, increased sweat, pupil ...
... at which point there can be gustatory sweating and tears from the eyes. Some tasters note the strong, fruity Fatalii flavour, ...
Skin glands Sweat gland Sebaceous gland Nail Lunule Breast Nipple Mammary gland Lactiferous duct Lactiferous sinus Areola ... duct Endolymphatic duct Cochlear labyrinth Cochlear duct Spiral organ Spiral ganglion Vessels of inner ear Gustatory organ ...
... and gustatory sweating are more frequently identified in mortalities. Medicine portal Dopamine beta hydroxylase deficiency ... This may affect the functioning of the heart, bladder, intestines, sweat glands, pupils, and blood vessels. Dysautonomia has ... QSART or thermoregulatory sweat test). Additional tests and examinations to determine a diagnosis of dysautonomia include: ... Testing for orthostatic intolerance Thermoregulatory sweat test Tilt table test Valsalva maneuver Tests to elucidate the cause ...
... gustatory sweating (also known as Frey's syndrome). Other long-term adverse effects include: Ultrastructural changes in the ... leading to excessive sweating regardless of environmental temperature through olfactory or gustatory stimulation. In addition, ... A lumbar sympathectomy was also developed and used to treat excessive sweating of the feet and other ailments, and typically ... The rates of severe compensatory sweating vary widely between studies, ranging from as high as 92% of patients. Of those ...
... sweating, gustatory MeSH C17.800.946.370 - hypohidrosis MeSH C17.800.946.492 - miliaria MeSH C17.800.946.492.285 - Fox-Fordyce ... sweat gland neoplasms MeSH C17.800.893.592 - leg ulcer MeSH C17.800.893.592.450 - foot ulcer MeSH C17.800.893.592.450.200 - ... disease MeSH C17.800.946.743 - sweat gland neoplasms The list continues at List of MeSH codes (C18). (Wikipedia articles in ...
... symptomatic sweating of only the hands or feet) or gustatory hyperhidrosis (sweating of the face or chest a few moments after ... Additionally, anxiety caused by self-consciousness to the sweating may aggravate the sweating. Excessive sweating of the feet ... such as sweat gland suction, retrodermal curettage, and axillary liposuction, Vaser, or Laser Sweat Ablation. Sweat gland ... Other possible side-effects include Horner's Syndrome (about 1%), gustatory sweating (less than 25%) and excessive dryness of ...
... fetid sweat, malodorous sweating, osmidrosis) Bubble hair deformity Central centrifugal cicatricial alopecia (follicular ... Generalized hyperhidrosis Graham-Little syndrome Granulosis rubra nasi Green nails Gustatory hyperhidrosis Hair casts ( ... sclerosing sweat duct carcinoma) Micronodular basal cell carcinoma Milia en plaque Milium Mixed tumor (chondroid syringoma) ... degeneration syndrome, pseudopelade of the central scalp) Chevron nail (herringbone nail) Chromhidrosis (colored sweat) Chronic ...
"FDA OKs first drug made to reduce excessive sweating". AP News. Archived from the original on 2018-07-02. Retrieved 2018-07-02 ... It has been used topically and orally to treat hyperhidrosis, in particular, gustatory hyperhidrosis. In inhalable form it is ... In June 2018, glycopyrronium was approved by the US Food and Drug Administration (FDA) to treat excessive underarm sweating, ... Kim WO, Kil HK, Yoon DM, Cho MJ (August 2003). "Treatment of compensatory gustatory hyperhidrosis with topical glycopyrrolate ...
The gustatory cortex is responsible for the perception of taste. Teeth - Temple - Temporal arteries, deep - Temporal artery, ... It also provides the under-arm sweat gland. Axillary artery - is a large blood vessel that conveys oxygenated blood to the ... p. 1. ISBN 978-0-9565668-3-6. Trivedi, Bijal P. (2012). "Gustatory system: The finer points of taste". Nature. 486 (7403): S2- ... The gustatory system or sense of taste is the sensory system that is partially responsible for the perception of taste (flavor ...
... sweating (e.g. sweat lodge), fasting, thirsting, and the consumption of psychotropic drugs such as cannabis. Sensory modality ... Gustatory: driving through the sense of taste and indigestion; including: starvation, herbs, hallucinogens and drugs. As the ...
... s do not have sweat glands and release heat through their mouths. They often sleep with their mouths open and may pant ... Underwater food detection is presumably gustatory and tactile. Crocodiles can hear well; their tympanic membranes are concealed ...
Parabrachial checks if the pain is being received in normal temperatures and if the gustatory system is active; if both are so ... Nociception can also cause generalized autonomic responses before or without reaching consciousness to cause pallor, sweating, ...
These include hair, sweat glands, sebaceous glands, and sensory nerves. The skin is made up of three microscopic layers: ... developing gustatory sense (taste) and swallowing. The tongue contains two sets of muscles, the intrinsic- involved with shape ...
Excessive sweating Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort ... gustatory, or olfactory, or delusions, that is, irrational beliefs. Hallucinations are generally stereotyped and without ...
Information is then passed from here through the thalamus into the gustatory cortex. Autonomic functions of the brain include ... sweating, and other homeostatic mechanisms. The hypothalamus also plays a role in thermal regulation, and when stimulated by ...
A condition called gustatory rhinitis can cause some individuals to sneeze after eating, particularly after the consumption of ... He hypothesized that the sun's heat caused sweating inside the nose, which triggered a sneeze in order to remove the moisture. ... Raphael G, Raphael MH, Kaliner M (1989). "Gustatory rhinitis: a syndrome of food-induced rhinorrhea". J. Allergy Clin. Immunol ...
The most common symptoms are general discomfort, headache, stomach awareness, nausea, vomiting, pallor, sweating, fatigue, ... Hyperreality Mixed reality Virtual body Virtual globe Virtual machining Virtual reality in Nursing Metaverse Gustatory ...
... sweating and elevated heart rate in the case of the grizzly bear) as the emotion fear. Their theory was devised as a result of ... olfactory and gustatory stimuli, and in memory for emotional information. The amygdala receives information from both the ... begin to sweat, experience an elevated heart rate, and attempt to run. All of these things would happen at the same time. ...
A unique reported symptom of the Omicron variant is night sweats, particularly with the BA.5 subvariant. Also, loss of taste ... As of July 2020, the ECDC reported a prevalence rate of ~54% for gustatory dysfunction. Other neurological symptoms appear to ... Quann J (7 July 2022). "Luke O'Neill: Night sweats now a sign of BA.5 COVID variant". Newstalk. Retrieved 10 July 2022. " ... A June 2020 systematic review found a 24-54% prevalence of gustatory dysfunction for people with COVID-19. Another June 2020 ...
Olfactory and gustatory communication happens chemically through smells and tastes. There are large differences between species ... Non-verbal communication often happens unintentionally and unconsciously, like sweating or blushing but there are also ... Animal communication can take a variety of forms, including visual, auditory, tactile, olfactory, and gustatory communication. ...
... petrosal nerve greater superficial petrosal nerve Greater trochanter greater wing of sphenoid groin gubernaculum gums gustatory ... supraorbital foramen supraorbital nerve suprapatellar bursa sural nerve suspensory ligament sustentaculum tali suture sweat ...
Some foods can make you sweat. Find out why and when it might be a good idea to talk to your doctor about it. ... The Journal of Physiology: "Physiological Gustatory Sweating in a Warm Climate.". Journal of Medical Case Reports: "Post- ... Sweating is one sign of that. Other foods, like garlic and onion, may not make you sweat, but they can make your sweat smell ... Doctors call excessive sweating hyperhidrosis. When it happens after you eat, thats known as gustatory hyperhidrosis, or ...
This is quite different than when your face burns because you are already sweating. Most people experience sweating as a result ... is defined as sweating and flushing of the facial region that occurs when a person is eating, or even thinking about food.[5] ... Causes of Gustatory Sweating. There are several things that can cause gustatory sweating. The most common cause, by far, is ... Treatment for Gustatory Sweating. There are limited treatment options for those with gustatory sweating, however, the ...
Gustatory hyperhidrosis is excessive sweating classified under focal hyperhidrosis, that is, it is restricted to certain ... This type of sweating is known as Freys syndrome. Gustatory hyperhidrosis has been observed in diabetics with autonomic ... Excessive sweating, hyperhidrosis causes". patient.info. Retrieved 30 January 2021. v t e (Articles with short description, ...
Gustatory sweating. Surgical treatment may be considered as follows:. * Aggressive debridement or amputation for recalcitrant ... Autonomic - Neuropathy that may involve the cardiovascular, gastrointestinal, and genitourinary systems and the sweat glands ... or those with abnormal sweating may become easily overheated in hot conditions. In most cases, consultation with the patients ...
Sweating is the release of liquid from the bodys sweat glands. This liquid contains salt. This process is also called ... Sweating is the release of liquid from the bodys sweat glands. This liquid contains salt. This process is also called ... Spicy foods (known as "gustatory sweating"). *Warm temperatures. *Withdrawal from alcohol, sedatives, or narcotic painkillers ... Sweating helps your body stay cool. Sweat is commonly found under the arms, on the feet, and on the palms of the hands. ...
Improvement of diabetic autonomic gustatory sweating by botulinum toxin type A. Neurology. 2002; 59(12):1971-1973. ...
3. Gustatory hyperhidrosis There are occasional cases where sweating in the lip may also be triggered by intake of certain food ... This is called gustatory sweating, typically happening on the face or neck when you eat spicy food or consume hot drinks. ... And similar to secondary hyperhidrosis, gustatory sweating can also be a side effect of other existing illnesses that a person ... Treatments for Excessive Sweating There are times when excessive sweating can be a sign of a serious medical condition, and a ...
She presents with mild right-sided ptosis, the constricted pupil (miosis), and decreased sweating on the right side of her face ... The patients symptoms of mild right-sided ptosis, constricted pupil (miosis), and decreased sweating on the right side of her ... lack of sweating) on the affected side. These signs are not mentioned in the given options, but they are commonly associated ...
Article: As soon as you taste it - evidence for sequential and parallel processing of gustatory information. Corresponding ... Dont Sweat the Sweet Stuff. Oct 15, 2018. Sweet and bitter flavors are identified as soon as they are tasted, according to ... This behavior requires detecting, identifying, and deciding to act on gustatory information.. Kathrin Ohla and Raphael Wallroth ...
Here are 8 things you probably didnt know about sweat. ... This type of sweating is called gustatory sweating.. Sweating ... The No-Sweat Facts. Sweating while exercising comes with benefits Sweating while exercising has many benefits such as ... Sweat or odors may impact health. If you feel like youre sweating more or less than normal, notice that your sweat is smelling ... Body odor does not come with sweating. Sweat is mostly water so it doesnt smell, but when sweat produced in the apocrine ...
... gustatory, and trigeminal chemosensory disorders: Definitions, mechanisms, and potential treatments ... They include pheromones or hormone metabolites as sweat, urine, seminal fluid, and vaginal secretion; and (3) the trigeminal ... Endogenous neurogenesis processes of olfactory and gustatory cells. The olfactory and gustatory neurons in the human body are ... Figure 4 Distributional mapping of the five basic taste sensations on the tongue, the gustatory pathways, and the taste bud and ...
Hyperhidrosis is a disorder characterised by the increased production of sweat disproportionate to the amount required to ... Gustatory sweating (sweating after eating or seeing food that produces strong salivation. Chewing can also stimulate sweating) ... While bacterial metabolism of apocrine sweat usually causes the malodour, eccrine sweating can also become offensive after ... focal sweating that ceases during sleep.. If there is no obvious underlying cause on history and examination, and the ...
Kujtan finds that patients often have sweat problems confined to their armpits or hands. ... Some types of sweat are normal. Gustatory sweating is a good example. I love hot and sour soup, but to consume it I have to put ... Whats Sweat? from KidsHealth. ● Sweat from MedlinePlus. ● Sweating and Body Odor from Mayo Clinic. ● Hyperhidrosis, ... "When we are hot, the sweat glands are stimulated and release a watery substance which forms the basis of sweat. The sweat is ...
Laskawi R, Drobik C, Schönebeck C. Up-to-date report of botulinum toxin type A treatment in patients with gustatory sweating ( ...
Certain foods, even when not hot, may cause sweating during consumption or after eating ... Gustatory sweating is sweating that occurs on the forehead, and neck while eating, or thinking about food. This can happen on ... Gustatory sweating most commonly happens because of an injury or surgery affecting the salivary gland below ones ear (parotid ... When I go out with my friends, I tend to sweat all through the meal yet none of my friends is sweating. Why? Erinest ...
... gustatory sweating (sweating on cheek area when eats or smells or thinks of food) ... 1) after parotidectomy if injury of (2)auriculotemporal nerve-, cross-innervates with sympathetic fibers to sweat glands of ... sweating, palpitations4) IgG Ab to TSH receptor (long-acting thyroid stimulator=LATS or thyroid-stimulating immunoglobuli5) ...
... this happens through a process called gustatory facial sweating. Essentially, eating fiery food causes your face to sweat, and ... You know the drill: running nose, burning mouth, breaking a sweat. Whether youre digging into homemade chili, habanero fajitas ... when your sweat evaporates, you feel cooler.. Your immune system will get a boost.. Shutterstock. Apparently, a hot pepper a ...
... sparing the superficial lobe as it gives better cosmetic results and also there is less likelihood of gustatory sweating ...
Gustatory Sweating. Gustatory sweating, also known as Freys Syndrome is a distressing condition caused by nerve damage which ... However, for people suffering from Gustatory Sweating, the nerve signals go to sweat glands instead, so that sweat is produced ... The cause of Gustatory Sweating is usually nerve damage, which in turn is usually caused by diabetes mellitus, facial injuries ... We mentioned earlier on in this article that diabetes can cause nerve damage which leads to Gustatory Sweating, but the disease ...
Med. 78, 576 (1951). Clinical evaluation in treatment of gustatory sweating: O. Laccourreye et al., Laryngoscope 100, 1651 ( ...
... is used as a treatment for excessive sweating or extreme facial flushing. Read more or make a donation online ... Sometimes people will notice sweating when eating spicy or hot foods (this is called gustatory sweating). ... Excessive sweating Sweating is one of the ways we regulate our body temperature, it also helps to keep our skin moist. Sweat is ... An ETS involves cutting these sympathetic nerves which switches off the sweating. The sympathetic nerves that control the sweat ...
Freys Syndrome - Gustatory Sweating. Freys Syndrome - Gustatory Sweating. 3 MINUTES. The Parotid Gland. ...
Freys Syndrome: Gustatory Sweating *Post author:Dr. Jason Hamilton. What is Freys Syndrome? Question: I recently saw my ... Freys Syndrome - Facial sweating and flushing *Post author:Dr. Jason Hamilton. Is Freys Syndrome an avoidable surgical ... doctor because I began to have episodes of facial sweating and flushing that would occur during eating or sometimes after… ...
Frey syndrome or gustatory sweating. This is the most common long-term complication of parotid surgery. It occurs as a result ... The patient experiences facial sweating and flushing with meals. This complication is not commonly problematic. For significant ... of inappropriate autonomic reinnervation of sweat glands in the skin from parotid parasympathetics. ...
O Gustatory lacrimation,O Gustatory sweating,O Gynecomastia,O H-type rectovestibular fistula,O Hair follicle neoplasm,O Hair ... O Abnormal sweat electrolytes,O Abnormal sweat gland morphology,O Abnormal sweat homeostasis,O Abnormal synaptic transmission,O ... O Cold-induced sweating,O Cold-sensitive myotonia,O Colitis,O Collectionism,O Colliers sign,O Coloboma,O Colon cancer,O Colon ... O Aplasia of the sweat glands,O Aplasia of the tarsal bones,O Aplasia of the thymus,O Aplasia of the ulna,O Aplasia of the ...
Gustatory Sweating 45% * Recurrence 24% * Mucoepidermoid Carcinoma 19% * Frozen Sections 15% 14 Scopus citations ...
Freys Syndrome, also known as Gustatory Sweating Syndrome, is a disorder that occurs due to a facial nerve injury, after a ... Freys Syndrome, also known as Gustatory Sweating Syndrome, is a disorder that occurs due to a facial nerve injury, after a ... Scully, C., Langdon, J., & Evans, J. (2009). Marathon of eponyms: 6 Frey syndrome (Gustatory sweating). Oral diseases, 15(8), ... The disorder induces mild to intense sweating, when any sensation pertaining to food (such as smell, taste, sound, sight, ...
... gustatory sweating, anal fissures, familial benign pemphigus, dyshidrotic eczema, and surgical wound closures.1 ... The use of BoNTA in inverse psoriasis might act at the neuroglandular junction level to reduce local sweating and prevent the ... Thus, the hypothesized effects of BoNTA in reducing local sweating and reduced liberation of neuropeptides and proalgogenic ... After intradermal injection, efferent cholinergic innervation of sweat glands is completely blocked, making it a viable ...
The skin has mainly two types of sweat glands. ... Sweating is a natural mechanism of the body of cooling down its ... Here are some myths and facts about sweating. 1. Is it Bad To Sweat. Sweating is natural and its normal and safe to sweat, ... Is Sweating Bad or Good For Our Health. Abstract. Sweat is a salty, clear liquid produced by our gland in the skin. Sweating is ... Why Does Sweat Produce Bad Odor. As mentioned above, sweat is mostly made up of salt and water. Sweat also produces bad odor ...
  • Gustatory sweating / hyperhidrosis. (cancer.org)
  • Gustatory hyperhidrosis is excessive sweating classified under focal hyperhidrosis, that is, it is restricted to certain regions of the body. (wikipedia.org)
  • Gustatory hyperhidrosis has been observed in diabetics with autonomic neuropathy, and a variant of this disorder has been reported following surgical sympathectomy. (wikipedia.org)
  • Excessive sweating of any kind is called hyperhidrosis. (bydewey.com)
  • Primary hyperhidrosis is the most common cause of excessive sweating, but its cause isn't known. (ro.co)
  • Secondary hyperhidrosis, on the other hand, is excessive sweating due to some underlying cause. (ro.co)
  • Gustatory hyperhidrosis is simply when it happens after you eat. (ro.co)
  • Hyperhidrosis is excessive sweating, which can be focal or diffuse and has multiple causes. (msdmanuals.com)
  • Although such sweating is a normal response, patients with hyperhidrosis sweat excessively and under conditions that do not cause sweating in most people. (msdmanuals.com)
  • Hyperhidrosis may be defined as excessive sweating, beyond a level required to maintain normal body temperature in response to heat exposure or exercise. (arkansasbluecross.com)
  • Gustatory hyperhidrosis is an unusual iatrogenic cause of facial hyperhidrosis in response to hot or spicy foods, resulting from surgery to the parotid gland and subsequent aberrant regenerating parasympathetic fibers. (arkansasbluecross.com)
  • Botulinum toxin has also been investigated as a treatment of secondary gustatory hyperhidrosis. (arkansasbluecross.com)
  • In 2004 the FDA approved botulinum toxin type A (Botox) to treat primary axillary hyperhidrosis (severe underarm sweating) that cannot be managed by topical agents. (arkansasbluecross.com)
  • Excessive sweating or Hyperhidrosis can be a problem for men. (healthyvox.com)
  • Whether you'd like to read everything that's ever been published about Botox for excessive sweating, or you'd like to learn more about the long history of iontophoresis, or you're wondering if a research question you're interested in has already been studied, or not, the Know Sweat hyperhidrosis library is the perfect place to start. (sweathelp.org)
  • In some cases, excessive sweating could be the result of an underlying medical condition known as hyperhidrosis . (sweatshieldundershirt.com)
  • People who go through hyperhidrosis usually experience sweating so excessive that they can even have moisture dripping from their hands. (sweatshieldundershirt.com)
  • Different forms of hyperhidrosis are assigned specific T indicators (facial sweating may be a T2 or T3, for example). (myexcessivesweating.com)
  • Patients are willing to trade a more severe hyperhidrosis or extensive facial blushing for the effects of compensatory sweating. (myexcessivesweating.com)
  • While antiperspirants or iontophoresis are usually recommended as first line treatments for primary palmar hyperhidrosis, there is a possible exception if the patient's excessive sweating symptoms occur during, or are exacerbated by, known anxiety-provoking situations such as presentations at work, dramatic performances, etc. (sweathelp.org)
  • Hyperhidrosis is a disorder of excessive sweating due to the overstimulation of cholinergic receptors on eccrine glands. (dmchealth.care)
  • Excessive sweating or HYPERHIDROSIS which can be localized or generalized, predominantly noted in the axilla, groin, or palms of hands and soles of feet. (dmchealth.care)
  • Hyperhidrosis (excessive sweating) of the hands and feet: The young man, Mr. Simmons, suffered from an immoderate amount of perspiration on his digital extremities, so he asked his doctor who told him that it was a condition of acrohyperhidrosis . (wordinfo.info)
  • Hyperhidrosis is excessive sweating that affects the individual's quality of life, resulting in social and work impairment and emotional distress. (bcbsnd.com)
  • Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other underlying conditions. (bcbsnd.com)
  • Sweating is the release of liquid from the body's sweat glands. (medlineplus.gov)
  • The amount you sweat depends on how many sweat glands you have. (medlineplus.gov)
  • A person is born with about 2 to 4 million sweat glands, which begin to become fully active during puberty. (medlineplus.gov)
  • Men's sweat glands tend to be more active. (medlineplus.gov)
  • Our bodies have two to four million sweat glands. (baptisthealthsystem.com)
  • Sweat is mostly water so it doesn't smell, but when sweat produced in the apocrine glands is mixed with bacteria or hormone secretions, that's when sweat will start to develop an odor. (baptisthealthsystem.com)
  • The number of sweat glands varies from person to person and has a genetic basis. (bydewey.com)
  • Hormones can interact with sweat glands to make them active especially in adolescents. (bydewey.com)
  • Sweat glands have also been implicated in being able to secrete other substances such as sex pheromones. (bydewey.com)
  • Antiperspirants such as Aluminium Chlorohydrate are chemicals which irritate the sweat glands' openings making them narrower and less able to produce sweat. (bydewey.com)
  • It involves severing the nerves controlling the hyperactive sweat glands. (bydewey.com)
  • When we are hot, the sweat glands are stimulated and release a watery substance which forms the basis of sweat. (bydewey.com)
  • It sort of makes sense, even without science, that downing 50 hot dogs in five minutes would activate someone's sweat glands. (ro.co)
  • Introduction to Sweating Disorders There are two types of sweat glands: apocrine and eccrine. (msdmanuals.com)
  • Frey syndrome disrupts the auriculotemporal nerve, with subsequent inappropriate regeneration of parotid parasympathetic fibers into sympathetic fibers innervating local sweat glands in skin where the injury took place. (msdmanuals.com)
  • This is a microwave device designed to heat tissue at the dermal-hypodermal interface, the location of the sweat glands. (arkansasbluecross.com)
  • After all, men have over 2 million sweat glands. (healthyvox.com)
  • Both are caused by bacteria in special sweat glands which are found mainly in the armpits and groin. (healthyvox.com)
  • When your body temperature gets too high, the sweat glands secrete water to cool it down again. (healthyvox.com)
  • Antiperspirants work by blocking sweat glands. (healthyvox.com)
  • Caffeine stimulates your sweat glands and alcohol widens the blood vessels in your skin, which can also cause excessive sweating. (shield.co.za)
  • Nerves that cause us to salivate get confused with nerves in our sweat glands, so we sweat instead of producing saliva. (shield.co.za)
  • The sweat glands? (sweathelp.org)
  • Some people are born with excessive sweat glands situated in their hands, feet, and armpits. (sweatshieldundershirt.com)
  • Others could be affected by overactive nerves, which in turn overstimulate their sweat glands. (sweatshieldundershirt.com)
  • Generally speaking, both men and women have the same number of sweat glands-a seemingly innocuous two million of them. (sweatshieldundershirt.com)
  • Men and women have both types of glands, but studies have found that men not only sweat more "efficiently," but they also sweat slightly more than their female counterparts. (sweatshieldundershirt.com)
  • This condition causes profuse and even spontaneous sweating because the sweat glands fail to shut off. (sweatshieldundershirt.com)
  • DAN is damage to the nerves that control involuntary bodily functions and your internal organs, such as your stomach, bladder, heart, blood vessels and sweat glands. (promedclinic.com.au)
  • Endoscopic Transthoracic Sympathectomy (ETS) and surgical excision of axillary sweat glands, if conservative treatment (i.e., aluminum chloride or botulinum toxin, individually, and in combination) has failed. (bcbsnd.com)
  • Many patients I see often have sweat problems confined to their armpits or hands. (bydewey.com)
  • But the main triggers are outlined below and may cause facial sweating or excessive sweating in the armpits. (ro.co)
  • Sweat is commonly found under the arms, on the feet, and on the palms of the hands. (medlineplus.gov)
  • sweating that tends to affect the palms and fingers, though it can occur all over the hands. (medicalnewstoday.com)
  • During the first decade of life, children with CISS/CS develop profuse sweating of the face, arms, and chest with ambient temperatures below 18º to 22º C, and with other stimuli including nervousness or ingestion of sweets. (nih.gov)
  • Sage tea is a herbal remedy used for profuse sweating because of its astringent properties. (healthyvox.com)
  • Spicy food and hot drinks before bed can cause excessive sweating and/or night sweats. (shield.co.za)
  • You experience night sweats for no apparent reason. (dmchealth.care)
  • I love hot and sour soup, but to consume it I have to put up with the resulting excessive facial sweating, and jokes about how I eat on the run. (bydewey.com)
  • The auriculotemporal syndrome features facial flushing or sweating limited to the distribution of the auriculotemporal nerve and may develop after trauma to the parotid gland, in association with PAROTID NEOPLASMS , or following their surgical removal. (nih.gov)
  • Treatment options include applying antiperspirant to the facial skin, injecting botulinum toxin (Botox) in that region of the skin (which blocks the neurotransmitter that causes sweating), surgery to place a barrier just under skin or extensive middle ear surgery to cut the nerve that causes all of these problems near its origin. (reillyfps.com)
  • Scientists call the phenomenon "gustatory facial sweating," because indeed you usually start sweating in the face first. (lakeside.com)
  • Compensatory sweating is intense sweating after sympathectomy. (msdmanuals.com)
  • Compensatory sweating is unpredictable and cannot be precisely identified before surgery. (myexcessivesweating.com)
  • In spite of sympathectomy surgery side effects, most patients agree that they would rather experience compensatory sweating than the condition they had before surgery. (myexcessivesweating.com)
  • In the cases where compensatory sweating is exceeding the expected levels, the titanium clamp may be removed. (myexcessivesweating.com)
  • When the denervation area affected by the surgical procedure of sympathectomy is extended, the side effect of compensatory sweating also increase in intensity. (myexcessivesweating.com)
  • Modern methods greatly reduce the levels of compensatory sweating. (myexcessivesweating.com)
  • By targeting the exact section of the sympathetic nerves, the surgeon doesn't allow compensatory sweating to aggravate. (myexcessivesweating.com)
  • Successful treatment of compensatory sweating can also be achieved by the use of medication. (myexcessivesweating.com)
  • Sweating is the body's natural way of regulating temperature. (medlineplus.gov)
  • Some people with sudomotor dysfunction can experience excessive sweating, as the body's way to compensate. (promedclinic.com.au)
  • Drinking caffeinated beverages can cause you to sweat excessively. (healthyvox.com)
  • Where do you sweat excessively? (sweathelp.org)
  • However, there are cases of people who sweat excessively during relatively mild weather or in the absence of sickness. (sweatshieldundershirt.com)
  • Because the same neurotransmitter that stimulates salivary release also stimulates sweating, whenever that nerve is activated, it causes sweating instead of salivary release. (reillyfps.com)
  • Lower room temperature a little bit to prevent more sweating. (medlineplus.gov)
  • Warm temperature is the most common trigger for sweating, but there are more sweating factors than we know. (baptisthealthsystem.com)
  • This could explain why you're suddenly sweating in a restaurant that was a comfortable temperature for you just moments ago. (ro.co)
  • For example, sweating around the lips and mouth can occur when ingesting foods and beverages that are spicy or hot in temperature. (msdmanuals.com)
  • Alcohol causes our body temperature to rise by increasing our blood flow and sugar level, so we sweat more to compensate. (shield.co.za)
  • Sweating abnormalities, such as excessive or decreased sweating, which affects the ability to regulate body temperature. (tudiabetes.org)
  • This disorder is characterized by sweating beyond what the body uses for homeostatic temperature regulation. (dmchealth.care)
  • SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. (uchicago.edu)
  • 22. Mechanisms of physiological gustatory sweating and flushing in the face. (nih.gov)
  • Sweating is a physiological mechanism used to control body heat. (bydewey.com)
  • Heat, anxiety , and certain foods and drinks can trigger sweating . (medicalnewstoday.com)
  • As a result, the misplaced parasympathetic fibers (which normally cause salivation as a gustatory response) now instead trigger sympathetic fibers that cause (inappropriate) redness and sweating of the preauricular cheek. (msdmanuals.com)
  • Loss of sweating over the affected site due to loss of autonomic function occurs in leprosy. (bvsalud.org)
  • Sweat occurs in cases of fever to help the body regain equilibrium. (sweatshieldundershirt.com)
  • Excessive sweating occurs when the sympathetic nerves become over active. (myexcessivesweating.com)
  • Gustatory sweating is an abnormal production of sweat that occurs soon after eating food. (promedclinic.com.au)
  • Many sympathectomy patients only experience very little moisture and sweating and hot weather seems to favor this phenomenon. (myexcessivesweating.com)
  • Also, Diabetic Autonomic Neuropathy can cause Sudomotor Dysfunction which means that the thermos-regulatory sweating, the way your body keeps cool, is damaged. (promedclinic.com.au)
  • Various factors , including obesity and menopause , can change how much or how often the body sweats. (medicalnewstoday.com)
  • An autonomic disorder characterized by excessive sweating of the forehead, upper lip, perioral region, or sternum subsequent to gustatory stimuli. (nih.gov)
  • The sweating begins on the forehead and then spreads to the face, scalp and neck. (promedclinic.com.au)
  • This type of sweating is known as Frey's syndrome. (wikipedia.org)
  • Many experts also consider tap water iontophoresis to be a first line treatment for palmar sweating. (sweathelp.org)
  • Herbs are a natural remedy that soothes the nerve fibers that cause you to produce excessive sweat. (healthyvox.com)
  • and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS ). (bvsalud.org)
  • Eventually it results in "global anhidrosis", the inability to sweat at all. (promedclinic.com.au)
  • Topical antiperspirants can be very effective, but are limited by irritation that is caused by the formation of hydrochloric acid in a chemical reaction between the aluminum chloride and sweat present on the skin surface. (sweathelp.org)
  • Generally, it's recommended that prescription antiperspirants containing aluminum chloride be applied before sleep (when sweating is at its most minimal) and washed off 6 to 8 hours later. (sweathelp.org)
  • Your blood circulation increases, you start sweating and once your moisture has evaporated, you've cooled off. (lakeside.com)
  • Sweating helps your body stay cool. (medlineplus.gov)
  • Wash your face and body if the salt from sweat has dried on your skin. (medlineplus.gov)
  • Sweating is the natural cooling reaction of the body to prevent it from overheating. (baptisthealthsystem.com)
  • Excessive sweating means sweating even when there is no overheating of the body to be cooled down. (baptisthealthsystem.com)
  • The sweat is released onto the skin and then evaporates, cooling down the body. (bydewey.com)
  • Sweating and Body Odor from Mayo Clinic. (bydewey.com)
  • Sweating is a vital function, it helps the body cool down. (medicalnewstoday.com)
  • If the body sweats when it does not need to cool, doctors consider the sweating to be excessive. (medicalnewstoday.com)
  • Spicy foods, especially from capsaicin-containing peppers, warm your body, which in turn makes you sweat,' explains Dana Hunnes, Ph.D., RD, MPH, senior dietitian at Ronald Reagan UCLA Medical Center and an adjunct assistant professor at the UCLA Fielding School of Public Health. (ro.co)
  • If sugar is making you sweat, it's likely because your body is producing too much insulin in response to what you ate. (ro.co)
  • Generalized sweating involves most of the body. (msdmanuals.com)
  • Body odor and sweat stains are not desirable. (healthyvox.com)
  • The water prevents your body from overheating and preventing the need to sweat. (healthyvox.com)
  • Whether you're a trainer in a gym, a regular bike rider or a man who generally has sweat issues in the groin area, you need a men's body powder that is specifically designed for your crotch area. (healthyvox.com)
  • Overconsumption of alcohol can also make your sweat smell, causing more pronounced body odour. (shield.co.za)
  • The body also views alcohol as a toxin, so it works harder to get rid of it via our liver, but also through urine and sweat. (shield.co.za)
  • Much like a refined AC, your body automatically produces sweat to cool you down when temperatures get a little hot. (sweatshieldundershirt.com)
  • In the absence of heat, sweat could be an indication that your body is fighting something off. (sweatshieldundershirt.com)
  • Sometimes, an overweight person may sweat more because their body biologically needs to exert more energy to accomplish daily functions. (sweatshieldundershirt.com)
  • The research revealed that sweat rates heavily depend on heat production, which is based on dynamics such as environment and body size rather than overall cardiac fitness. (sweatshieldundershirt.com)
  • Some foods have greater thermogenic effects than others and will, therefore, make the body sweat more during or soon after a meal. (sweatshieldundershirt.com)
  • This is even more dangerous, as when you don't sweat your body can't cool itself, which can lead to overheating and potentially heatstroke. (promedclinic.com.au)
  • Excessive sweating on one side of the body. (wordinfo.info)
  • The sweating can sometimes cause emotional and psychological distress and interfere with daily activities. (medicalnewstoday.com)
  • The key to control sweat and unpleasant odors starts with regular bathing with an unscented soap. (bydewey.com)
  • These can range from damage to the autonomic nerves controlling the sweat pores to various hormonal disorders and obesity. (bydewey.com)
  • Sorry, we can't do anything about sweating on that dinner date if it's about nerves. (ro.co)
  • In some cases, sweating after eating is related to your nerves and not to the food on the menu. (ro.co)
  • Does/did anyone else experience unusual sweating like this, in the absence of diabetes or some other condition? (cancer.org)
  • Simpler measures such as blow drying sweat prone areas after bathing will help reduce bacterial counts. (bydewey.com)
  • Toronto Doctors: Botox Treatment for Excessive Sweating, from No Sweat Clinic. (bydewey.com)
  • Drink plenty of fluids (water, or fluids containing electrolytes such as sports drinks) to replace sweat. (medlineplus.gov)
  • Excessive sweating in the groin that results in itchy/scratchy nuts and fungal infections. (healthyvox.com)
  • Constant sweat in the groin region increases your risk of developing fungal infections. (healthyvox.com)
  • Not sweating or sweating less can be dangerous and may lead to heat stroke, which is a life-threatening condition. (baptisthealthsystem.com)
  • Eating large amounts of food or food with high levels of pepper or spice can cause sweat due to the heat and spice they contain. (shield.co.za)
  • One quirky symptom of GP is that I experience something know as "gustatory sweating. (tudiabetes.org)
  • If you feel like you're sweating more or less than normal, notice that your sweat is smelling different than normal or impacts your professional and personal life, please consult a doctor for proper diagnosis and treatment. (baptisthealthsystem.com)
  • Is it normal to sweat a lot while eating? (shield.co.za)
  • 1. Due to its blocking effects on the release of acetylcholine it is very useful in the managment of cervical dystonia, spasmodic dysphonia, oro mandibular dystonia and Gustatory sweating. (drtbalu.co)
  • Does food & drink sweat smell? (shield.co.za)
  • Onions, garlic, spicy foods and dairy products can all cause your sweat to smell. (shield.co.za)
  • Options for the treatment of cold-induced sweating include clonidine alone, clonidine plus amitryptyline, or moxonidine alone. (nih.gov)
  • But it's worth noting that a food that triggers you alone may not cause sweating if eaten along with a source of quality fat or fiber to slow digestion. (ro.co)
  • However, very little scientific evidence indicates that these treatments stop excessive sweating. (medicalnewstoday.com)
  • Pharmacologic treatments for cold-induced sweating should be discontinued during pregnancy, as teratogenic effects on the fetus have not been well studied and remain a possibility. (nih.gov)
  • Why do I sweat when I drink alcohol? (shield.co.za)
  • Excessive sweating at night can be caused by increased alcohol consumption. (shield.co.za)
  • How can I stop alcohol sweats or sweating when eating? (shield.co.za)
  • Can certain foods make you sweat? (ro.co)
  • Although the science is still torn on whether the meat sweats are real, experts agree certain foods can get the juices flowing. (ro.co)
  • There are a couple of categories of foods that are the main culprits if you find yourself sweating after eating: spicy foods and (possibly) sugary foods. (ro.co)
  • Acidic foods, like those that contain vinegar, may increase the likelihood of sweating as well as foods served hot, like soup. (ro.co)
  • To be clear right off the bat, we're not saying sugary foods will always cause sweating after eating for some people. (ro.co)
  • Sweating after eating can be a problem for some people - all foods or just thinking about food can make them sweat. (shield.co.za)
  • Yet other substances in sweat can react with the bacteria normally found in the armpit. (bydewey.com)
  • He doesn't really sweat at night, but these episodes (which can happen immediately or up to an hour later, and occasionally randomly during the day) could be considered "drenching," perhaps. (cancer.org)

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