Tabes Dorsalis
'Oblongata' crises in tabes dorsalis. (1/19)
A patient in the pre-ataxic stage of tabes dorsalis suffered from gastric crises, but in addition had numerous episodes of apnoea and coma which in the older literature have been described as 'oblongata crises'--the presumption being that the crises are due to a brain stem disturbance. (+info)Flaccid paraplegia: a feature of spinal cord lesions in Holmes-Adie syndrome and tabes dorsalis. (2/19)
In a patient with Holmes-Adie syndrome, and in another with tabes dorsalis, a transverse cord lesion resulted in a severe, but flaccid paraplegia with absent tendon reflexes. Flexor spasms were severe in both patients, but spasticity was absent. The significance of these observations is discussed in relation to the functional and anatomical disorder in these two syndromes. (+info)Rapidly progressive tabes dorsalis associated with selective IgA deficiency. (3/19)
Tabes dorsalis is uncommon and progresses slowly from infection to clinical manifestation. We report a rare case of rapidly progressive tabes dorsalis associated with selective IgA deficiency (sIgAD). A 28-year-old man was hospitalized with lightning back pain, nausea, and bladder bowel dysfunction. Serum and cerebrospinal fluid (CSF) revealed high titers of Treponema pallidum antibody, and the serum IgA level was less than 5 mg/dl. Thl-dominant cytokine expression was observed, as is usually seen in neurosyphilis. He was treated with Ceftriaxone and CSF pleocytosis disappeared. We postulate sIgAD influenced the atypical rapid clinical course of tabes dorsalis in this patient. (+info)Tabes dorsalis with sudden onset of paraplegia. (4/19)
A case is presented of tabes dorsalis with spinal gumma producing collapse of the L5 vertebra followed by paraplegia. (+info)Neurosyphilis manifesting as spinal transverse myelitis. (5/19)
Spinal myelitis caused by neurosyphilis is an extremely rare disease, and there are only few visual examples of magnetic resonance imaging scans. We present a clinical case of neurosyphilis, which is of great importance concerning diagnostic, differential diagnosis, and tactics of management. A patient complaining of progressive legs weakness, numbness, and shooting-like pain in the legs as well as pelvic dysfunction was admitted to the hospital. Neurological examination revealed spinal cord lesion symptoms: legs weakness, impairment of superficial and deep sensation together with pathological symptoms in the legs. Hernia of intervertebral disc or tumor was suspected, and myelography with computed tomography of the spine was performed. No pathological findings were observed. More precise examination of the patient (a small scar in the genitals and condylomata lata in anal region were noticed) pointed to possible syphilis-induced spinal cord lesion. Serologic syphilis diagnostic tests (Treponema pallidum hemagglutination assay, reagin plasma response, serum enzyme-linked immunosorbent assay) and cerebrospinal fluid tests (general cerebrospinal fluid test and Venereal Disease Research Laboratory test) confirmed the diagnosis of neurosyphilis. Spinal cord lesion determined by magnetic resonance imaging was evaluated as spinal syphilis or syphilis-induced myelitis. Conventional treatment showed a partial effect. (+info)Case report: Neuropathic arthropathy of the hip as a sequela of undiagnosed tertiary syphilis. (6/19)
(+info)Meningovascular neurosyphilis: a report of stroke in a young adult. (7/19)
A young adult patient with meningovascular neurosyphilis in the form of acute ischemic stroke with right hemiparesis and speech disturbance is reported. CT scan showed features of ischemic infarct and extensive laboratory studies were made before the diagnosis ultimately was revealed. Such cases could result in confusion for the clinician, and high index of clinical suspicion of this condition is required since syphilis is not routinely tested, as routine screening is seen to be of low diagnostic yield. As clinical practice indicates, it remains a difficult problem approaching diagnosis of neurosyphilis, and this is achieved through exclusion of neurosyphilis as a clinical possibility. (+info)Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. (8/19)
(+info)Tabes dorsalis is a late-stage complication of untreated neurosyphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. It is characterized by degeneration of the posterior columns and dorsal roots of the spinal cord, leading to various neurological symptoms.
The medical definition of Tabes Dorsalis is:
A chronic progressive degenerative disease of the spinal cord, specifically affecting the dorsal root ganglia and posterior columns, caused by the tertiary stage of syphilis. The condition is characterized by a combination of motor, sensory, and autonomic disturbances, including ataxia, Romberg's sign, lightning pains, hypo- or areflexia, impaired proprioception, dissociated sensations, and Argyll Robertson pupils. If left untreated, Tabes Dorsalis can lead to significant disability and even death.
Tabes dorsalis
Abadie's sign of tabes dorsalis
Posterior spinal artery syndrome
Syphilis
Max Westenhöfer
Lumleian Lectures
Abadie's sign of exophthalmic goiter
Neurosyphilis
Joseph Abadie
Jean Nageotte
Albert Pitres
Rezső Bálint (physician)
Anton Ludwig Ernst Horn
Heinrich Lissauer
Demyelinating disease
Meningeal syphilis
Ira Van Gieson
General paresis of the insane
Alfred Fuchs
Joseph Babinski
Wilhelm Heinrich Erb
Jean Alexandre Barré
Locomotor ataxia
André Léri
Ernst Viktor von Leyden
James Pilling
Adolf Strümpell
Hermann Oppenheim
Stomping gait
Dmitry Dashkov
Tabes dorsalis - Wikipedia
The Medical Kipling-Syphilis, Tabes Dorsalis, and Romberg's Test - Volume 10, Number 6-June 2004 - Emerging Infectious Diseases...
Tabes dorsalis progressing to general paresis after 20 years despite routine penicillin therapy. | Sexually Transmitted...
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Neurosyphilis2
- Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). (wikipedia.org)
- The last 3 and most severe forms of neurosyphilis is general paresis (GPI), meniningovascular syphilis, and tabes dorsalis. (bartleby.com)
Syphilis6
- citation needed] Tabes dorsalis is caused by demyelination by advanced syphilis infection (tertiary syphilis) when the primary infection by the causative spirochete bacterium, Treponema pallidum, is left untreated for an extended period of time (past the point of blood infection by the organism). (wikipedia.org)
- Poet Charles Baudelaire contracted syphilis in 1839 and resorted to opium to help alleviate the pain of tabes dorsalis ascending his spine. (wikipedia.org)
- Painter Édouard Manet died of syphilis complications, including tabes dorsalis, in 1883, aged 51. (wikipedia.org)
- A man with a history of treatment for early syphilis presented with tabes dorsalis. (bmj.com)
- Title : The Medical Kipling-Syphilis, Tabes Dorsalis, and Romberg's Test Personal Author(s) : Vora, Setu K.;Lyons, Robert W. (cdc.gov)
- Tertiary syphilis can present with cardiac involvement, gummatous lesions, tabes dorsalis, and general paresis. (cdc.gov)
Completed his doctorate2
- Sir Arthur Conan Doyle, author of the Sherlock Holmes stories, completed his doctorate on tabes dorsalis in 1885. (wikipedia.org)
- He completed his doctorate on the subject of tabes dorsalis in 1885. (goodreads.com)
Peripheral1
- If there are glove and stocking hypoesthesia and hypoactive reflexes, one should consider peripheral neuropathy or tabes dorsalis. (checkorphan.org)
Lesions1
- Flaccid paraplegia: a feature of spinal cord lesions in Holmes-Adie syndrome and tabes dorsalis. (bmj.com)
Penicillin1
- Tabes dorsalis progressing to general paresis after 20 years despite routine penicillin therapy. (bmj.com)
Infection1
- The incidence of tabes dorsalis is rising, in part due to co-associated HIV infection. (wikipedia.org)
Physical2
- Those with tabes dorsalis may also require physical therapy and occupational therapy to deal with muscle wasting and weakness. (wikipedia.org)
- A B., a man, aged 54, married, was sent to me in the summer of 1925 with definite physical signs of beginning tabes dorsalis. (jamanetwork.com)
Pain2
- A complication of tabes dorsalis can be transient neuralgic paroxysmal pain affecting the eyes and the ophthalmic areas, previously called "Pel's crises" after Dutch physician P.K. Pel. (wikipedia.org)
- Tabes dorsalgia" is a related lancinating back pain. (wikipedia.org)