Thoracic neoplasms are a broad category of abnormal growths or tumors that originate within the thorax, encompassing malignant (cancerous) and benign (non-cancerous) forms, which can affect structures such as the lungs, pleura, mediastinum, and chest wall.
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Neoplasms containing cyst-like formations or producing mucin or serum.
Tumors or cancer of the SKIN.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Tumors or cancers of the KIDNEY.
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)
Tumors or cancer of the THYROID GLAND.
Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.

A large intrathoracic parathyroid adenoma. (1/341)

A case is described in which an unusually large parathyroid adenoma was visible on the plain chest radiograph taken during the investigation of hypercalcaemia. This was diagnosed preoperatively and a scheme is suggested whereby such a disgnosis can now readily be made. The differential diagnosis is discussed ant the literature is reviewed.  (+info)

Prenatal sonographic features of embryonal rhabdomyosarcoma. (2/341)

We describe a case of fetal rhabdomyosarcoma detected during the third trimester of pregnancy by prenatal sonography. At 33 weeks' gestation, sonography performed because of suspected polyhydramnios showed a solid mass of 120 x 54 mm arising from the anterior wall of the fetal thoracic cage. Another mass within the left maxillary area which originated from the left orbital floor was also detected. In the abdomen, there were multiple round masses in and around the liver. As the previous scan at 28 weeks had appeared normal, the multiple masses which became visible and enlarged rapidly in different locations led us to believe that there was fetal cancer. The most likely diagnosis was rhabdomyosarcoma (which was later confirmed), because it is the most prevalent soft-tissue tumor in children and may develop within or outside muscle anywhere in the body and at any age. Two other reported cases which were detected by prenatal ultrasound examination are also discussed.  (+info)

Sternal splitting approach to upper thoracic lesions located anterior to the spinal cord. (3/341)

The sternal splitting approach for upper thoracic lesions located anterior to the spinal cord is described. The sternal splitting approach can be effectively applied to lesions from the T-1 to T-3 levels. The aortic arch prevents procedures below this level. The approach is straight toward the T1-3 vertebral bodies and provides good surgical orientation. The sternal splitting approach was applied to five patients with metastatic spinal tumors at the C7-T3 levels and three patients with ossification of the posterior longitudinal ligament at the T1-3 levels. No postoperative neurological deterioration occurred. Two patients had postoperative hoarseness. The sternal splitting approach to the upper thoracic spine is recommended for hard lesions, extensive lesions requiring radical resection, and lesions requiring postoperative stabilization with spinal instrumentation.  (+info)

Comparison of dual-head coincidence PET versus ring PET in tumor patients. (4/341)

This study compared the multiring detector (Ring-PET) and the dual-head coincidence imaging system (DH-PET) for staging/ restaging neoplastic patients before or after surgery or radiochemotherapy. METHODS: Seventy patients with suspected tumor recurrence or metastatic dissemination received an intravenous dose of 18F-fluorodeoxyglucose (FDG) under overnight fasting and were studied in sequence with a dedicated positron emission tomograph with Ring-PET and a DH-PET. Ring-PET studies were performed 45-75 min postinjection and were followed by a DH-PET scan approximately 3 h postinjection. Number and location of the hypermetabolic lesions detected on DH-PET and Ring-PET reconstructed images were blindly assessed by three independent observers. RESULTS: DH-PET identified all 14 head lesions detected by Ring-PET, 53 of 63 thoracic lesions and 36 of 45 abdominal lesions. Of the 19 lesions not identified by DH-PET, 6 were smaller than 10 mm, 8 were between 10 and 15 mm and 1 was 18 mm; dimensions of 4 bone lesions were not available. A concordant restaging, based on location and number of lesions detected, was found in all 14 patients with head tumors, in 28 of 30 patients with thoracic tumors and in 24 of 26 patients with abdominal tumors. CONCLUSION: We found a good agreement between Ring-PET and DH-PET assessment of oncologic patients in detecting hypermetabolic lesions > or = 10-15 mm.  (+info)

Moderate dose-escalation of combination chemotherapy with concomitant thoracic radiotherapy in limited-disease small-cell lung cancer: prolonged intrathoracic tumor control and high central nervous system relapse rate. Groupe d'Oncologie-Pneumologie Clinique de l'Universite Catholique de Louvain, Brussels and Liege, Belgium. (5/341)

BACKGROUND: The role of chemotherapy dose-intensification in small-cell lung cancer (SCLC) remains unclear. This phase I-II study evaluates feasibility and outcome of combination chemotherapy at moderately elevated doses with concomitant thoracic radiotherapy in limited-disease SCLC. PATIENTS AND METHODS: Moderately elevated doses of ifosfamide-epirubicin (cycles 1 and 3) and of carboplatin-etoposide (cycles 2 and 4) were given with G-CSF and peripheral blood stem-cell (PBSC) support. Thoracic radiotherapy (40 Gy) was given once daily during the first five days of each cycle. RESULTS: Overall toxicity was acceptable; most common side-effects were myelosuppression and asthenia. All 35 eligible patients responded (23 CR, 12 PR). Median time to progression was 15 months: median overall survival was 24.6 months. Only 6 of 25 relapsing patients (24%) presented with a locoregional recurrence while 12 of 25 (48%) relapsed in the central nervous system (CNS). CONCLUSIONS: This regimen is a feasible dose-intensification with an acceptable toxicity profile. Its efficacy was demonstrated by a 100% response rate, an excellent local tumor control rate and a median survival of 24.6 months. In the absence of PCI, CNS relapse is a major problem if adequate local control is achieved.  (+info)

How do general practitioners respond to reports of abnormal chest X-rays? (6/341)

General practitioners (GPs) in the UK have long had direct access to hospital radiological services, which in theory shortens investigation time and improves the quality of service. Chest X-rays (CXRs) account for a substantial proportion of requests, and we investigated what happened when an abnormality was detected. In one year, 204 GPs in the Nottingham area requested CXRs in 605 patients. 362 were reported normal, 165 abnormal but hospital follow-up not indicated and 71 abnormal with radiological follow-up or hospital referral indicated (mass lesion suspicious of tumours 27, infective shadowing 35, other 9). 64 of the 71 were seen in hospital within three months, and in those with suspected cancer the median time to follow-up was 20 days. These results show that GPs do act on the results of abnormal CXRs, but only 37% of those with a mass suspicious of cancer were seen in hospital within two weeks as recommended by the British Thoracic Society. Time might be saved if GPs agreed to direct referral from the radiology department to respiratory physicians.  (+info)

Extramedullary myeloid cell tumour: presentation as anterior chest wall mass during AML relapse. (7/341)

Acute myeloid leukaemia is an uncommon but an important cause of soft tissue swellings. Such extrameningeal, extramedullary leukaemic infiltrates are called extramedullary myeloid cell tumours. Despite their large size they may respond well to chemotherapy and local radiotherapy, as is demonstrated in this case.  (+info)

LMCE3 treatment strategy: results in 99 consecutively diagnosed stage 4 neuroblastomas in children older than 1 year at diagnosis. (8/341)

PURPOSE: To tailor postinduction therapy for stage 4 neuroblastoma in children who are older than 1 year at diagnosis according to status after induction. PATIENTS AND METHODS: From March 1987 to December 1992, 99 patients who were consecutively admitted were included in the Lyon-Marseille-Curie East of France (LMCE)3 strategy. After induction with the French Society of Pediatric Oncology NB87 regimen and surgery, patients who were in complete remission immediately proceeded to consolidation therapy with vincristine, melphalan, and fractionated total-body irradiation (VMT). All other patients underwent a postinduction strategy before VMT, either an additional megatherapy regimen or further chemotherapy with etoposide/carboplatin. RESULTS: The progression-free survival (PFS) is 29% at 7 years from diagnosis, which compares favorably with that of a similar cohort of 72 patients previously reported by our group (LMCE1; PFS of 20% at 5 years and 8% at 14 years, P =.004). In the multivariate analysis, only age younger than 3 years at diagnosis (P =.0085) and achievement of complete or very good partial remission after NB87 and surgery (P =.00024) remained significant. The PFS of the 87 patients who were included in the postinduction strategy was significantly better than that of the comparable 62 patients on the LMCE1 study (32% v 11% at 7 years; P =.005). CONCLUSION: The progressive improvements in the LMCE results over the last 10 years suggest that improvements in supportive care measures and increases in each component of this strategy (induction, postinduction, consolidation) may all contribute to increased survival rates.  (+info)

Thoracic neoplasms refer to abnormal growths or tumors that develop in the thorax, which is the area of the body that includes the chest and lungs. These neoplasms can be benign (non-cancerous) or malignant (cancerous). Malignant thoracic neoplasms are often referred to as lung cancer, but they can also include other types of cancer such as mesothelioma, thymoma, and esophageal cancer.

Thoracic neoplasms can cause various symptoms depending on their location and size. Common symptoms include coughing, chest pain, shortness of breath, hoarseness, and difficulty swallowing. Treatment options for thoracic neoplasms depend on the type, stage, and location of the tumor, as well as the patient's overall health. Treatment may include surgery, radiation therapy, chemotherapy, targeted therapy, or a combination of these approaches.

Pancreatic neoplasms refer to abnormal growths in the pancreas that can be benign or malignant. The pancreas is a gland located behind the stomach that produces hormones and digestive enzymes. Pancreatic neoplasms can interfere with the normal functioning of the pancreas, leading to various health complications.

Benign pancreatic neoplasms are non-cancerous growths that do not spread to other parts of the body. They are usually removed through surgery to prevent any potential complications, such as blocking the bile duct or causing pain.

Malignant pancreatic neoplasms, also known as pancreatic cancer, are cancerous growths that can invade and destroy surrounding tissues and organs. They can also spread (metastasize) to other parts of the body, such as the liver, lungs, or bones. Pancreatic cancer is often aggressive and difficult to treat, with a poor prognosis.

There are several types of pancreatic neoplasms, including adenocarcinomas, neuroendocrine tumors, solid pseudopapillary neoplasms, and cystic neoplasms. The specific type of neoplasm is determined through various diagnostic tests, such as imaging studies, biopsies, and blood tests. Treatment options depend on the type, stage, and location of the neoplasm, as well as the patient's overall health and preferences.

Neoplasms are abnormal growths of cells or tissues in the body that serve no physiological function. They can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow growing and do not spread to other parts of the body, while malignant neoplasms are aggressive, invasive, and can metastasize to distant sites.

Neoplasms occur when there is a dysregulation in the normal process of cell division and differentiation, leading to uncontrolled growth and accumulation of cells. This can result from genetic mutations or other factors such as viral infections, environmental exposures, or hormonal imbalances.

Neoplasms can develop in any organ or tissue of the body and can cause various symptoms depending on their size, location, and type. Treatment options for neoplasms include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, among others.

Neoplasms: Neoplasms refer to abnormal growths of tissue that can be benign (non-cancerous) or malignant (cancerous). They occur when the normal control mechanisms that regulate cell growth and division are disrupted, leading to uncontrolled cell proliferation.

Cystic Neoplasms: Cystic neoplasms are tumors that contain fluid-filled sacs or cysts. These tumors can be benign or malignant and can occur in various organs of the body, including the pancreas, ovary, and liver.

Mucinous Neoplasms: Mucinous neoplasms are a type of cystic neoplasm that is characterized by the production of mucin, a gel-like substance produced by certain types of cells. These tumors can occur in various organs, including the ovary, pancreas, and colon. Mucinous neoplasms can be benign or malignant, and malignant forms are often aggressive and have a poor prognosis.

Serous Neoplasms: Serous neoplasms are another type of cystic neoplasm that is characterized by the production of serous fluid, which is a thin, watery fluid. These tumors commonly occur in the ovary and can be benign or malignant. Malignant serous neoplasms are often aggressive and have a poor prognosis.

In summary, neoplasms refer to abnormal tissue growths that can be benign or malignant. Cystic neoplasms contain fluid-filled sacs and can occur in various organs of the body. Mucinous neoplasms produce a gel-like substance called mucin and can also occur in various organs, while serous neoplasms produce thin, watery fluid and commonly occur in the ovary. Both mucinous and serous neoplasms can be benign or malignant, with malignant forms often being aggressive and having a poor prognosis.

Skin neoplasms refer to abnormal growths or tumors in the skin that can be benign (non-cancerous) or malignant (cancerous). They result from uncontrolled multiplication of skin cells, which can form various types of lesions. These growths may appear as lumps, bumps, sores, patches, or discolored areas on the skin.

Benign skin neoplasms include conditions such as moles, warts, and seborrheic keratoses, while malignant skin neoplasms are primarily classified into melanoma, squamous cell carcinoma, and basal cell carcinoma. These three types of cancerous skin growths are collectively known as non-melanoma skin cancers (NMSCs). Melanoma is the most aggressive and dangerous form of skin cancer, while NMSCs tend to be less invasive but more common.

It's essential to monitor any changes in existing skin lesions or the appearance of new growths and consult a healthcare professional for proper evaluation and treatment if needed.

Multiple primary neoplasms refer to the occurrence of more than one primary malignant tumor in an individual, where each tumor is unrelated to the other and originates from separate cells or organs. This differs from metastatic cancer, where a single malignancy spreads to multiple sites in the body. Multiple primary neoplasms can be synchronous (occurring at the same time) or metachronous (occurring at different times). The risk of developing multiple primary neoplasms increases with age and is associated with certain genetic predispositions, environmental factors, and lifestyle choices such as smoking and alcohol consumption.

Kidney neoplasms refer to abnormal growths or tumors in the kidney tissues that can be benign (non-cancerous) or malignant (cancerous). These growths can originate from various types of kidney cells, including the renal tubules, glomeruli, and the renal pelvis.

Malignant kidney neoplasms are also known as kidney cancers, with renal cell carcinoma being the most common type. Benign kidney neoplasms include renal adenomas, oncocytomas, and angiomyolipomas. While benign neoplasms are generally not life-threatening, they can still cause problems if they grow large enough to compromise kidney function or if they undergo malignant transformation.

Early detection and appropriate management of kidney neoplasms are crucial for improving patient outcomes and overall prognosis. Regular medical check-ups, imaging studies, and urinalysis can help in the early identification of these growths, allowing for timely intervention and treatment.

A "second primary neoplasm" is a distinct, new cancer or malignancy that develops in a person who has already had a previous cancer. It is not a recurrence or metastasis of the original tumor, but rather an independent cancer that arises in a different location or organ system. The development of second primary neoplasms can be influenced by various factors such as genetic predisposition, environmental exposures, and previous treatments like chemotherapy or radiation therapy.

It is important to note that the definition of "second primary neoplasm" may vary slightly depending on the specific source or context. In general medical usage, it refers to a new, separate cancer; however, in some research or clinical settings, there might be more precise criteria for defining and diagnosing second primary neoplasms.

Adenocarcinoma, mucinous is a type of cancer that begins in the glandular cells that line certain organs and produce mucin, a substance that lubricates and protects tissues. This type of cancer is characterized by the presence of abundant pools of mucin within the tumor. It typically develops in organs such as the colon, rectum, lungs, pancreas, and ovaries.

Mucinous adenocarcinomas tend to have a distinct appearance under the microscope, with large pools of mucin pushing aside the cancer cells. They may also have a different clinical behavior compared to other types of adenocarcinomas, such as being more aggressive or having a worse prognosis in some cases.

It is important to note that while a diagnosis of adenocarcinoma, mucinous can be serious, the prognosis and treatment options may vary depending on several factors, including the location of the cancer, the stage at which it was diagnosed, and the individual's overall health.

Thyroid neoplasms refer to abnormal growths or tumors in the thyroid gland, which can be benign (non-cancerous) or malignant (cancerous). These growths can vary in size and may cause a noticeable lump or nodule in the neck. Thyroid neoplasms can also affect the function of the thyroid gland, leading to hormonal imbalances and related symptoms. The exact causes of thyroid neoplasms are not fully understood, but risk factors include radiation exposure, family history, and certain genetic conditions. It is important to note that most thyroid nodules are benign, but a proper medical evaluation is necessary to determine the nature of the growth and develop an appropriate treatment plan.

Myeloproliferative disorders (MPDs) are a group of rare, chronic blood cancers that originate from the abnormal proliferation or growth of one or more types of blood-forming cells in the bone marrow. These disorders result in an overproduction of mature but dysfunctional blood cells, which can lead to serious complications such as blood clots, bleeding, and organ damage.

There are several subtypes of MPDs, including:

1. Chronic Myeloid Leukemia (CML): A disorder characterized by the overproduction of mature granulocytes (a type of white blood cell) in the bone marrow, leading to an increased number of these cells in the blood. CML is caused by a genetic mutation that results in the formation of the BCR-ABL fusion protein, which drives uncontrolled cell growth and division.
2. Polycythemia Vera (PV): A disorder characterized by the overproduction of all three types of blood cells - red blood cells, white blood cells, and platelets - in the bone marrow. This can lead to an increased risk of blood clots, bleeding, and enlargement of the spleen.
3. Essential Thrombocythemia (ET): A disorder characterized by the overproduction of platelets in the bone marrow, leading to an increased risk of blood clots and bleeding.
4. Primary Myelofibrosis (PMF): A disorder characterized by the replacement of normal bone marrow tissue with scar tissue, leading to impaired blood cell production and anemia, enlargement of the spleen, and increased risk of infections and bleeding.
5. Chronic Neutrophilic Leukemia (CNL): A rare disorder characterized by the overproduction of neutrophils (a type of white blood cell) in the bone marrow, leading to an increased number of these cells in the blood. CNL can lead to an increased risk of infections and organ damage.

MPDs are typically treated with a combination of therapies, including chemotherapy, targeted therapy, immunotherapy, and stem cell transplantation. The choice of treatment depends on several factors, including the subtype of MPD, the patient's age and overall health, and the presence of any comorbidities.

Chatzopoulos K, Boland JM (January 2021). "Update on genetically defined lung neoplasms: NUT carcinoma and thoracic SMARCA4- ... of the neoplasms associated with the BRD4-NUTM1 fusion gene. These questions also apply to a wide range of neoplasms that have ... It is generally accepted that the BRD4-NUT protein promotes these neoplasms by maintaining their neoplastic cells in a ... Luo W, Stevens TM, Stafford P, Miettinen M, Gatalica Z, Vranic S (November 2021). "NUTM1-Rearranged Neoplasms-A Heterogeneous ...
2016-01-01), "Approach to Tracheobronchial Neoplasms", Specialty Imaging: Thoracic Neoplasms, Specialty Imaging, Philadelphia: ...
Open 2015, 2, 2329048X14567531 Psarros TG, Swift D, Mulne AF et al (2005) Neurocytoma-like neoplasm of the thoracic spine in a ... and described as diffuse oligodendroglial-like leptomeningeal tumor of children in the 2016 classification of CNS neoplasms by ... rate of concurrent BRAF-KIAA1549 gene fusion and 1p deletion in disseminated oligodendroglioma-like leptomeningeal neoplasms ( ...
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In 2007 he dedicated his efforts to further his interests in Brain and Thoracic Tumor Clinical Trials interests, as well as ... He has run numerous multimodality clinical trials at the national level for both adult and pediatric CNS neoplasms. Current ... Combined modality treatment of tumors of the CNS and thorax, as well as pediatric neoplasms: integrating systemic chemotherapy ... and thoracic oncology started in 1988 and was marked by a zealous focus on evidence-based medicine through clinical and ...
Diseases of the skin include skin infections and skin neoplasms (including skin cancer). Dermatology is the branch of medicine ... There are seven cervical, twelve thoracic, five lumbar, and five sacral. Certain diseases like shingles, caused by varicella- ...
Neoplasms benign, malignant and unspecified (incl cysts and polyps); Nervous system disorders; Pregnancy, puerperium and ... thoracic and mediastinal disorders; Skin and subcutaneous tissue disorders; Social circumstances; Surgical and medical ...
He served as director of the American Board of Thoracic Surgery from 1977 to 1983, and was named the Stuart Harrington (S. W. ... Kaiser LR: Surgical treatment of thymic epithelial neoplasms. Hematol Oncol Clin North Am 2008; 22: 475-488. Skeie GO, Romi F: ... He went on to pursue subspecialty fellowship training in thoracic surgery, a field that was developing rapidly in the 1950s. ... Philip Eugene Bernatz (April 18, 1921 - October 6, 2010) was an eminent American physician and thoracic surgeon at the Mayo ...
See: "C16 - Malignant neoplasm of the stomach". ICD-10 Version: 2015. World Health Organization. Archived from the original on ... The thoracoabdominal approach opens the abdominal and thoracic cavities together, the two-stage Ivor Lewis (also called Lewis- ... Shields TW, LoCicero JW, Reed CE, Feins RH (2009). General Thoracic Surgery. Lippincott Williams & Wilkins. pp. 2047-. ISBN 978 ... Journal of Thoracic Disease. 6 (Suppl 3): S289-S297. doi:10.3978/j.issn.2072-1439.2014.03.11. PMC 4037413. PMID 24876933. ...
Oncology-related conditions, namely neoplasms and myelomatous pleural effusion have been associated with chest pain. Chest pain ... thoracic disk herniation, and rib fracture. Rheumatologic conditions such as fibromyalgia, SAPHO syndrome, ankylosing ... Polish Journal of Cardio-Thoracic Surgery (in English and Polish). 15 (3): 180-2. doi:10.5114/kitp.2018.78443. PMC 6180027. ...
Young, Robert H. (2004). "Pseudomyxoma peritonei and selected other aspects of the spread of appendiceal neoplasms". Seminars ... European Journal of Cardio-Thoracic Surgery. 21 (3): 508-513. doi:10.1016/S1010-7940(01)01166-6. ISSN 1010-7940. PMID 11888772 ...
Although most neoplasms can present with fever, malignant lymphoma is by far the most common diagnosis of FUO among the ... ADEM (acute disseminated encephalomyelitis) Adrenal insufficiency Aneurysm Anomalous thoracic duct Aortic dissection Aortic- ... neoplasms. In some cases the fever even precedes lymphadenopathy detectable by physical examination. ...
In the 2000s, scientific research conducted by the institution focused on various domains: neoplasm, injury and their ... Anatomy Department of Anesthesiology and Intensive Care Department of Medical Biology and Biochemistry Department of Thoracic ... Neoplasms and Tuberculosis Department of Infectious Diseases and Hepatology Department of Dermatology and Venereology ...
August 2016). "Rare airway tumors: an update on current diagnostic and management strategies". Journal of Thoracic Disease. 8 ( ... Benign neoplasms, Respiratory system neoplasia). ...
... cervical or thoracic spinal stenosis Subglottic stenosis (SGS) Tracheal stenosis Obstructive jaundice (biliary tract stenosis) ... alcohol atherosclerosis birth defects calcification diabetes headbanging iatrogenic infection inflammation ischemia neoplasm ...
Journal of Thoracic Disease 5:E17-20 Tsao MS, Fraser RS (1991) Primary pulmonary adenocarcinoma with enteric differentiation. ... Neoplasm stubs). ... Journal of Thoracic Disease. 5 (1): E17-20. doi:10.3978/j.issn. ...
Cardio-thoracic surgeon established the college's department of cardio-thoracic surgery in 1964. M. R. Rajagopal, a palliative ... Research areas include iron-deficiency Anemia, neoplasms of blood and infectious diseases. One among the expert committee which ... A recipient of the Padma Bhushan and the Indian National Science Academy's Shree Dhanwantari Prize, the cardio-thoracic surgeon ...
EWSR1-SMAD3-positive fibroblastic tumor: These tumors, which are a recently characterized neoplasm with distinct ... Thoracic Cancer. 12 (3): 314-323. doi:10.1111/1759-7714.13727. PMC 7862796. PMID 33314685. Sloan EA, Chiang J, Villanueva-Meyer ... a wide range of soft tissue neoplasms derived from mesencyhmal tissue cells. Detection of a FET gene-containing fusion gene is ... "EWSR1/FUS-CREB fusions define a distinctive malignant epithelioid neoplasm with predilection for mesothelial-lined cavities". ...
"Results of a multicenter, prospective trial of thoracic endovascular aortic repair for blunt thoracic aortic injury (RESCUE ... Simons JP, Ng SC, Shah SA, McDade TP, Whalen GF, Tseng JF (2009). "Malignant Intraductal Papillary Mucinous Neoplasm: Are We ... American Society of Thoracic Surgery (ASTS) database National Trauma Data Bank (NTDB) Scientific Registry of Transplant ... April 2007). "The midterm results of stent graft treatment of thoracic aortic injuries". J. Surg. Res. 138 (2): 181-8. doi: ...
A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an ... The Annals of Thoracic Surgery. 86 (6): 1769-1772. doi:10.1016/j.athoracsur.2008.08.033. PMID 19021972. Meghana Deshmukh, ... When seen on upper gastrointestinal series, a pancreatic rest may appear to be a submucosal mass or gastric neoplasm. Most are ... Case report: ectopic pancreatic rest in the proximal stomach mimicking gastric neoplasms. Clin Radiol. 2007 Jun;62(6):600-2. ...
"Types and mechanisms of pulmonary atelectasis." Journal of thoracic imaging 11.2 (1996): 92-108. White, Gary C. (2002). Basic ... "Lung folding simulating peripheral pulmonary neoplasm (Blesovsky's syndrome)". Thorax. 35 (12): 936-940. doi:10.1136/thx.35.12. ... Risk factors associated with increased likelihood of the development of atelectasis include: type of surgery (thoracic, ...
While many general surgeons are actively involved in treating patients with malignant neoplasms, the designation of "surgical ... Most often, surgical oncologist refers to a general surgical oncologist (a subspecialty of general surgery), but thoracic ...
They account for less than 1% of all breast neoplasms. They were previously termed cystosarcoma phyllodes, coined by Johannes ... Journal of Thoracic Disease. 8 (11): 3361-3368. doi:10.21037/jtd.2016.11.03. PMC 5179374. PMID 28066617. Komenaka IK, El-Tamer ... Phyllodes tumors account for approximately 1% of all breast neoplasms. They primarily occur in adult women, with very few ...
... syndrome Thong-Douglas-Ferrante syndrome Thoracic celosomia Thoracic dysplasia-hydrocephalus syndrome Thoracic outlet syndrome ... Temtamy-Shalash syndrome TEN Ter Haar-Hamel-Hendricks syndrome Ter Haar syndrome Teratocarcinosarcoma Teratoma Testes neoplasm ... mental retardation Thymic carcinoma Thymic epithelial tumor Thymic renal anal lung dysplasia Thymoma Thymus neoplasm ... syndrome Tolosa-Hunt syndrome Toluene antenatal infection Tomaculous neuropathy Tome-Brune-Fardeau syndrome Tongue neoplasm ...
Two prominent examples are pediatric neoplasms (such as medulloblastoma) and prostate cancer. Irreversible long-term side ... hence a reduction of acute thoracic, gastrointestinal and bladder side effects. Proton therapy for eye tumors is a special case ...
Approximately 99% of lung cancers are carcinoma, a term that indicates that the malignant neoplasm is composed of, or descended ... The current generally accepted standard of care for all forms of SCLC is concurrent chemotherapy (CT) and thoracic radiation ... April 2008). "Genetic alterations in combined neuroendocrine neoplasms of the lung". Mod. Pathol. 21 (4): 414-22. doi:10.1038/ ... Glenn's thoracic and cardiovascular surgery (6th ed.). Norwalk CT: Appleton & Lange. pp. 357-389. Brambilla E, Moro D, Gazzeri ...
The Journal of Thoracic and Cardiovascular Surgery. 91 (3): 389-396. doi:10.1016/s0022-5223(19)36054-4. PMID 3951243. Reynen, K ... Melanocytic nevi and neoplasms, Syndromes affecting the skin, Syndromes affecting the heart, Syndromes with tumors). ... "Pancreatic ductal and acinar cell neoplasms in Carney complex: a possible new association". J Clin Endocrinol Metab. 96 (11): ... Epithelioid blue nevus List of cutaneous neoplasms associated with systemic syndromes Carney Syndrome at eMedicine Carney, J.; ...
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... Thoracic Cancer. 11 (10): 3011-3014. doi:10.1111/1759-7714.13613. PMC 7529570. PMID 32815307. Sbaraglia M, Bellan E, Dei Tos AP ... thoracic cavity, abdominal cavity, peritoneum, heart, brain, and spinal cord. Microscopic histopathological analyses of ...
Thoracic Surgical Anatomy and Procedures", Medical Management of the Thoracic Surgery Patient, Philadelphia: W.B. Saunders, pp ... hemiazygos system displayed by chest or abdominal X-ray films can be misdiagnosed as a mediastinal or retroperitoneal neoplasm ... It continues ascending on the left side of the vertebral column, and around the level of the ninth thoracic vertebra, it passes ... The hemiazygos vein (vena azygos minor inferior) is a vein running superiorly in the lower thoracic region, just to the left ...
Thorax Thoracic. Thorax Thoracic ICD-10-CM Neoplasms Index The ICD-10-CM Neoplasms Index is designed to allow medical coders to ... There are 2 terms under the parent term Thorax Thoracic in the ICD-10-CM Neoplasms Index. ... Source: http://icd.codes/icd10cm/neoplasms-index/thorax-thoracic ... ICD-10-CM Neoplasms Index. *Terms Beginning With T Neoplasms ...
Do you qualify for these Thoracic Neoplasms studies? Were researching treatments for 2023. ... Thoracic Neoplasms clinical trials at UCSD 1 research study open to eligible people ...
Many Faces of Thoracic Neoplasms Case 4. Many Faces of Thoracic Neoplasms Case 4. ...
Thoracic Neoplasms / surgery * Urethral Obstruction / surgery ...
Chatzopoulos K, Boland JM (January 2021). "Update on genetically defined lung neoplasms: NUT carcinoma and thoracic SMARCA4- ... of the neoplasms associated with the BRD4-NUTM1 fusion gene. These questions also apply to a wide range of neoplasms that have ... It is generally accepted that the BRD4-NUT protein promotes these neoplasms by maintaining their neoplastic cells in a ... Luo W, Stevens TM, Stafford P, Miettinen M, Gatalica Z, Vranic S (November 2021). "NUTM1-Rearranged Neoplasms-A Heterogeneous ...
Categories: Thoracic Neoplasms Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted ...
Digestive System Neoplasms. Carcinoma, Neuroendocrine. Endocrine Gland Neoplasms. Neoplasms, Thoracic. Gastrointestinal ... Lymphedema Melanoma Merkel Cell Carcinoma Mesothelioma Multiple Myeloma Myelodysplastic Syndrome Myeloproliferative Neoplasms ...
Thoracic Neoplasms in Children. Matthew A.Zapala, Victor M.Ho-Fung, Edward Y.Lee ... Reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones. J Bone Joint Surg Am 2007;89(10 ... Common Skeletal Neoplasms and Nonneoplastic Lesions at 18F-FDG PET/CT. RadioGraphics2021 ... Hyaline cartilage-origin bone and soft-tissue neoplasms: MR appearance and histologic correlation. Radiology 1988;167(2):477- ...
Breast Neoplasms, Central Nervous System Neoplasms, Medical Oncology Board Review: XVI Curso de Revisão em Hematologia e ... Medical Oncology, Thoracic Neoplasms V Congreso en Oncologia y Radioterapia. Lima - Peru ... Pediatrics, Surgical Oncology, Medical Oncology, Breast Neoplasms XIV Board Review in Medical Oncology: Atualização, Discussão ...
Weakness of intrinsic muscles of the hand is due to other pathology (e.g: thoracic outlet pressure, neoplasm of lung, and ulnar ... In regards to T1 and T2 myotomes/muscle weakness: Disc lesions at upper two thoracic levels do not appear to give rise to root ... The explanation for the correct answer is that disc lesions at the upper two thoracic levels do not cause root weakness. ... In this case, the abdomen and lumbar region are innervated by the thoracic spinal nerves T8-T12. Paresthesias, which are ...
The prevalence of neoplasia within the study population was 3.2%. The most commonly diagnosed neoplasms were squamous cell ... Within the group of goats diagnosed with thoracic neoplasia, the most common neoplasm was a thymoma. The majority (3/4 [75%]) ... Thoracic neoplasia. Thoracic masses were diagnosed in 13 of 46 (28%) goats. Breeds in this group included Pygmy (n = 4), Nubian ... Four of the uterine neoplasms were leiomyosarcoma (4/6 [67%]) with the remaining neoplasms identified as leiomyofibroma (1/6 [ ...
Breast Neoplasms, Prostatic Neoplasms, Thoracic Neoplasms, Neoplasia gastrointestinales, Atención Integral, Medicina ... Colorectal Neoplasms, Hereditary Nonpolyposis, Epidemiology, Colonoscopy, Genetics, Colorectal Neoplasms, Gastroenterology ... Head and Neck Neoplasms, Diagnosis, Medical Oncology, Otolaryngology, Factores pronóstico IV Jornada Paulista de Mastologia ...
Lung Neoplasms. Carcinoma, Non-Small-Cell Lung. Respiratory Tract Neoplasms. Thoracic Neoplasms. Neoplasms by Site. Neoplasms. ... Bronchial Neoplasms. Bevacizumab. Atezolizumab. Carboplatin. Gemcitabine. Docetaxel. Pemetrexed. Vemurafenib. Entrectinib. ...
... thoracic neoplasms/ or exp *bone neoplasms/ or exp *endocrine gland neoplasms/ or exp *eye neoplasms/ or exp *"head and neck ... hematologic neoplasms/ or exp *nervous system neoplasms/ or exp *skin neoplasms/ or exp *splenic neoplasms/ or exp *thoracic ... cecal neoplasms/ or exp *duodenal neoplasms/ or exp *ileal neoplasms/ or exp *jejunal neoplasms/ or exp *stomach neoplasms/ or ... cecal neoplasms/ or exp *duodenal neoplasms/ or exp *ileal neoplasms/ or exp *jejunal neoplasms/ or exp *stomach neoplasms/ or ...
Neuroendocrine neoplasms (NENs). *Practical recommendations for the management of patients with gastroenteropancreatic and ... thoracic (carcinoid) neuroendocrine neoplasms in the COVID-19 era - ScienceDirect - co-authored by top NET experts from around ...
... thoracic neoplasms, foreign bodies, radiofrequency ablation for atrial fibrillation or esophageal surgery. An aortoesophageal ... esophageal SEMS insertion for a benign disease has rarely been reported and only in cases where there was a thoracic neoplasm, ... thoracic aortic aneurism, endovascular stent repair, foreign body or esophageal surgery. To our knowledge, this is the first ... is a rarely reported complication of esophageal SEMS and the majority of reported cases are secondary to thoracic aortic ...
Most frequently, metastatic seeding involves the thoracic spine (accounting for about 70% of cases), with the lumbar spine ... encoded search term (Spinal Cord Neoplasms) and Spinal Cord Neoplasms What to Read Next on Medscape ... Spinal Cord Neoplasms. Updated: Jul 17, 2019 * Author: Jesse Borke, MD, FACEP, FAAEM; Chief Editor: Barry E Brenner, MD, PhD, ... Anatomically, neoplasms of the spinal cord may be classified according to the compartment of origin, either intramedullary ( ...
PRIMARY PULMONARY NEOPLASMS OF CHILDHOOD - A REVIEW ANNALS OF THORACIC SURGERY Hartman, G. E., Shochat, S. J. 1983; 36 (1): 108 ... One hundred fifty-one tumors in these reports were classified as malignant lesions and 79 as benign neoplasms. Bronchial " ... Despite the rarity of primary pulmonary neoplasms in children, this diagnosis should be considered in young patients with ...
Neoplasms of the thin serous membrane that envelopes the lungs and lines the thoracic cavity. Pleural neoplasms are exceedingly ... "Pleural Neoplasms" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Pleural Neoplasms" by people in this website by year, and ... Below are the most recent publications written about "Pleural Neoplasms" by people in Profiles. ...
Thoracic Neoplasms +. 1465. Urogenital Neoplasms +. 2192. anal gland neoplasm. 0. organ system benign neoplasm +. 1289. ... A collective term for precoordinated organ/neoplasm headings locating neoplasms by organ, as BRAIN NEOPLASMS; DUODENAL ... NEOPLASMS; LIVER NEOPLASMS; etc.. Synonyms:. exact_synonym: Neoplasm Site; Neoplasm Sites; Neoplasms by Sites. ...
NeoplasmsHead and Neck NeoplasmsMandibular NeoplasmsCystadenocarcinomaMuscle NeoplasmsProstatic NeoplasmsThoracic Neoplasms ... Pancreatic NeoplasmsNeoplasmsLymphatic MetastasisSkin NeoplasmsNeoplasms, Cystic, Mucinous, and SerousLung NeoplasmsNeoplasms, ... Cord NeoplasmsVaginal NeoplasmsAdrenal Gland NeoplasmsNervous System NeoplasmsPenile NeoplasmsNeoplasm SeedingGenital Neoplasms ... Uterine NeoplasmsBreast NeoplasmsColonic NeoplasmsBone Marrow NeoplasmsEndocrine Gland NeoplasmsIntestinal NeoplasmsNeoplasms, ...
Thoracic Neoplasms; Stomach Neoplasms; Neoplasms; Carcinoma, Transitional Cell; Small Cell Lung Carcinoma; Esophageal ... Biliary Tract Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Colorectal Neoplasms; Melanoma. Details Tecaginlimab. BNT-312 ... Ovarian Neoplasms; Head and Neck Neoplasms; Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Papillomavirus Infections; ... Prostatic Neoplasms; Breast Neoplasms; Solid tumours; Triple Negative Breast Neoplasms; Neoplasms; Lymphoma, Large B-Cell, ...
Thoracic Neoplasms. Specialty. Medical Oncology. Notes. Preceded by: The IASLC multidisciplinary approach to thoracic oncology ... Neoplasms - diagnosis. Neoplasms - pathology. Subjects (LCSH). Cytology. Oncology. Pathology. Format. e-Book. Location. Online ... The IASLC multidisciplinary approach to thoracic oncology. Place of Publication. Philadelphia, PA. Publisher. Elsevier. Date of ... International association for the study of lung cancer - thoracic oncology. Former Title. ...
Professor of Pathology; Co-Leader, Cancer Signaling Networks, Yale Cancer Center; Scientific Director, Center for Thoracic ... Associate Professor of Therapeutic Radiology; Vice Chair for Clinical Research, Therapeutic Radiology; Chief, Thoracic ... Center for Thoracic Cancers, Yale Cancer Center and Smilow Cancer Hospital; Program Director, Master of Health Science - ...
Specialty Imaging: Thoracic Neoplasms. ISBN: 978-0-323-37706-5. Thanks in advance! ...
Neoplasms [C04]. *Neoplasms by Site [C04.588]. *Thoracic Neoplasms [C04.588.894]. *Respiratory Tract Neoplasms [C04.588.894.797 ...
  • BRD4 protein recognizes acetylated lysine residues on proteins and by doing so participates in the regulation of DNA replication, DNA transcription, and thereby key cellular processes involved in the development of neoplasms (i.e. malignant or benign tissue growths). (wikipedia.org)
  • Malignant neoplasms are sometimes associated with a variety of paraneoplastic rheumatic syndromes. (ogu.edu.tr)
  • Chondrosarcoma is the third most common bone tumor after myeloma and osteosarcoma, and the second most common malignant spinal tumor (i.e., represents 12% of all spinal neoplasms). (surgicalneurologyint.com)
  • In this study the authors investigated the surgical outcomes of cordotomy in patients with thoracic malignant astrocytomas to determine the effectiveness of this procedure. (elsevierpure.com)
  • Time is evenly split among the Surgical Oncology, Endocrine Surgery, and Thoracic Surgery services. (nih.gov)
  • The Endocrine Surgery service treatment for patients with thyroid, parathyroid, and adrenal gland neoplasms as well as neuroendocrine tumors. (nih.gov)
  • The Thoracic Surgery service treats patients with primary or metastatic disease of the lung in addition to mediastinal pathology. (nih.gov)
  • Thoracic splenosis is a rare, benign condition involving autotransplantation of splenic tissue into the pleural cavity via trauma or surgery. (biomedcentral.com)
  • Although the diagnosis of intrathoracic splenosis was established, the patient was referred to the thoracic surgery service because of symptoms refractory to pain control with analgesia as well as the interval growth of the mass. (biomedcentral.com)
  • Dr. Subrato Deb, MD is a Thoracic Surgery Specialist in Jacksonville, FL. (healthline.com)
  • They specialize in Thoracic Surgery, has 31 years of experience, and is board certified in General Surgery. (healthline.com)
  • Annals of Thoracic Surgery , 34 (6), 664-673. (usuhs.edu)
  • Minimally invasive surgery has continued to grow as an alternative approach to traditional open methods of treating cervical and thoracic spine pathologies, with similar efficacy, shorter hospitalizations and decreased tissue destruction. (jmisst.org)
  • This manuscript presents a review of the literature and summarizes complications seen in cervical and thoracic spine surgery, focusing on different types of minimally invasive procedures. (jmisst.org)
  • Open thoracic spinal surgery is also traditionally associated with a variety of complications. (jmisst.org)
  • Despite the known complications of open surgery involving the cervical and thoracic spine, complications associated with minimally invasive surgery (MIS) techniques remain unanswered. (jmisst.org)
  • The present review seeks to identify potential complications associated with cervical and thoracic spine surgery using the tubular, endoscopic tubular assisted, uniportal endoscopic, and biportal endoscopic surgical approaches. (jmisst.org)
  • Additionally, a search of the phrase "minimally-invasive cervical and thoracic spine surgery complications" was performed. (jmisst.org)
  • The titles and abstracts of the identified articles were then systematically assessed for any mention of minimally invasive tubular, endoscopic tubular-assisted, uniportal endoscopic, or biportal endoscopic surgery to the cervical or thoracic spine. (jmisst.org)
  • Adherence to Lung Cancer Screening by Low-dose Thoracic CT in Haut-Rhin Department, France. (ichgcp.net)
  • Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105. (wakehealth.edu)
  • The International Association for the Study of Lung Cancer and the Journal of Thoracic Oncology publish this annual update to help readers keep pace with these important developments. (elsevierpure.com)
  • 4. MR imaging of thoracic tumors in pediatric patients. (nih.gov)
  • 20. [MRT and ultrasound in diagnosis of cervico-thoracic lymphangioma: a radio-histologic comparison]. (nih.gov)
  • Neuroendocrine neoplasms exhibit variable symptomatology, such as tumor mass effects or the biologic consequences of the bioactive amine secretion, frequently delaying diagnosis. (snmjournals.org)
  • Since 2012, he has worked at the Medical Oncology Unit of Policlinico Paolo Giaccone in Palermo, Italy, focusing on the diagnosis, treatment, and study of solid neoplasms, in particular in the thoracic, gastrointestinal, and hepato-bilio-pancreatic areas. (upmc.it)
  • Fellows will spend eighteen months most frequently in one of several laboratories within the Surgical Oncology Program- or the Thoracic Surgical Oncology Branch. (nih.gov)
  • Journal of Thoracic Oncology , 12 (8), 1183-1209. (elsevierpure.com)
  • Dr. de Groot is sub-specialty trained and practices thoracic radiology with emphasis on oncology and infection in immunocompromised patients. (mdanderson.org)
  • Lateral Corpectomy for Spinal Neoplasms (Philip Louie, Matthew Colman). (dokumen.pub)
  • In humans, the nerves of the plexus usually originate from the lower cervical and the first thoracic spinal cord segments (C5-C8 and T1), but variations are not uncommon. (lookformedical.com)
  • a Kaposi's sarcoma of extremity, an infiltrative ductal carcinoma of breast and four different types of lung neoplasms. (tgcd.org.tr)
  • ligature around the thoracic duct and Pecquet's duct. (nih.gov)
  • From an anterior approach, injury to the great vessels is possible leading to hemorrhage as is damage to the thoracic duct leading to chylothorax [ 7 ]. (jmisst.org)
  • Standard therapy includes en-bloc resection, with accompanying radiation therapy (RT) and chemotherapy if complete resection is not possible. (medscape.com)
  • In patients with thoracic GBM, even if paralysis is incomplete, cordotomy should be performed before the tumor disseminates through the CSF. (elsevierpure.com)
  • Minimally Invasive Approaches to Thoracic and Lumbar Metastatic Spine Disease (Eric Vess, Bowen Qui, Addisu Mesfin). (dokumen.pub)
  • Diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the BRACHIAL PLEXUS. (chemwatch.net)
  • Inactivating mutations of the SMARCA4 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 4) gene and/or loss of the BRG1 (brahma-related gene 1) protein defines SMARCA4-deficient thoracic sarcoma (SMARCA4-dTS), an aggressive neoplasm with a usually fatal outcome. (nih.gov)
  • Somatostatin receptor (SSR) imaging offers an opportunity to identify receptor-expressing neuroendocrine neoplasms (NENs) ( 2 , 3 ). (snmjournals.org)
  • Thoracic magnetic resonance imaging (MRI) showed a mass between T7 and T9 that was isointense on T1W1 and markedly enhanced with gadolinium [ Figure 1 ]. (surgicalneurologyint.com)
  • Dorsal plane reconstruction thoracic CT image in the soft tissue window of the cat in Figures 1 and 2 . (avma.org)
  • Hypertrophic osteoarthropathy is one of these syndromes and the vast majority of cases are associated with intra thoracic neoplasms mainly broncogenic cancer. (ogu.edu.tr)
  • Thoracic splenosis is a rare entity resulting from splenic and diaphragmatic injury. (biomedcentral.com)
  • It has been suggested that removal of thoracic splenic tissue in patients without functional abdominal splenic tissue may render the patient asplenic, increasing the risk of infection [ 2 ], although this concept is still controversial. (biomedcentral.com)
  • One hundred ten patients with primary chest wall neoplasms were analyzed for long-term results. (usuhs.edu)
  • One-stage cordotomy should be indicated for patients with thoracic GBM or AA presenting with complete paraplegia preoperatively. (elsevierpure.com)
  • Första besöket till kliniken gjordes mellan 2010 och 2019, uppföljningsbesök har ännu inte pÃ¥börjats men förhoppningen är att en sÃ¥dan runda kan pÃ¥börjas under 2022. (gu.se)
  • Journal of Thoracic Disease , 12 (11), 6952-6953. (elsevierpure.com)
  • 2. Thoracic disease in children with AIDS. (nih.gov)
  • This article provides a guide to the performance and interpretation of 68 Ga-DOTATATE PET/CT and describes its role in the diagnostic algorithm of neuroendocrine neoplasms and its overall utility in their management. (snmjournals.org)
  • The cardiovascular admission category includes admissions related to cardiovascular failure or insufficiency from hypertensive crisis, rhythm disturbances, acute decompensation of heart failure, hemorrhagic/hypovolemic shock, sepsis and dissecting thoracic/abdominal aneurysm. (medscape.com)
  • Bone is one of the most common anatomic sites for metastases, along with the lungs and liver, and metastases are the most commonly diagnosed neoplasms encountered in the skeleton. (basicmedicalkey.com)
  • Same images as in Figure 1 (A and B) plus colli-mated right lateral (C) and ventrodorsal (D) thoracic radio-graphic images of the same bat. (avma.org)
  • It is generally accepted that the BRD4-NUT protein promotes these neoplasms by maintaining their neoplastic cells in a perpetually undifferentiated, proliferative state. (wikipedia.org)
  • Further studies are needed to confirm and expand these views and to determine if any of the overexpressed gene products of the BRD4-NUT protein contribute to the development and/or progression, or can serve as targets for the treatment, of the neoplasms associated with the BRD4-NUTM1 fusion gene. (wikipedia.org)