Pancreatic Neoplasms
Neoplasms
Neoplasms, Cystic, Mucinous, and Serous
Neoplasms, Multiple Primary
Neoplasms, Second Primary
Cystic lymph node metastases of squamous cell carcinoma of Waldeyer's ring origin. (1/140)
We analysed in a retrospective study the frequency of cystic lymph node (LN) metastases in neck dissection specimens of 123 patients with primary squamous cell carcinoma (SCC) arising in the palatine tonsils (62 M/14 F), the base of the tongue (38 M/5 F) and the nasopharynx (2 M/2 F). Eighty-two per cent of patients had metastases (64 tonsillar SCC, 33 base of tongue SCC and all four nasopharynx SCC) in 368 LN of a total 2298 sampled LN. Thirty-nine per cent of patients had exclusively solid metastases and 37% of patients had exclusively cystic metastases. A total of 62 patients had some signs of cyst formation in one or more metastatically affected LN (27 with only histological evidence of cyst formation with luminal diameters < 5 mm, 35 with clinically detectable cyst with luminal diameter > 5 mm). Cystic metastases were more common in patients with SCC of the base of the tongue (P = 0.005), while solitary clinically evident cystic metastasis with lumina > 5 mm were found exclusively in tonsillar carcinoma (P = 0.024). In comparison with solid metastases, cyst formation was associated with N-categories (N2b and N3, P = 0.005) in SCC of the base of the tongue origin. No such association was observed for tonsillar SCC (P = 0.65). The primary mechanism of cyst formation was cystic degeneration. (+info)Giant fibrovascular polyp of the oropharynx. (2/140)
We describe a case of a giant fibrovascular polyp arising from the oropharynx and causing vague clinical symptoms. To our knowledge, this is the first description of an oropharyngeal fibrovascular polyp reported in the medical literature. The diagnosis was based on MR imaging findings, which showed the size and configuration of the polyp as well as the site of attachment. The patient underwent surgery, and the diagnosis was confirmed histologically. (+info)Clinical management of six cases of low-risk primary tonsillar non-Hodgkin's lymphoma. (3/140)
CONTEXT: There have been many reports that favor aggressive systemic treatment with chemotherapy and radiotherapy, even for well-localized lymphomas, avoiding the need for tonsillectomy of the normal tonsil. CASE REPORT: We report six cases of primary tonsillar lymphoma with a median patient age of 42 years. There were two lymphoma cases with diffuse large cells, two cases with mixed small and large cells, one with small cells and one indeterminate. They were treated with six cycles of chemotherapy and cervical radiotherapy. All patients achieved durable complete remission. Our data agree with previous reports that suggested that primary tonsillar high-grade B-cell NHL has a good prognosis if aggressively treated. (+info)Radiation therapy for squamous cell carcinoma of the tonsillar region: a preferred alternative to surgery? (4/140)
PURPOSE: There are no definitive randomized studies that compare radiotherapy (RT) with surgery for tonsillar cancer. The purpose of this study was to evaluate the results of RT alone and RT combined with a planned neck dissection for carcinoma of the tonsillar area and to compare these data with the results of treatment with primary surgery. PATIENTS AND METHODS: Four hundred patients were treated between October 1964 and December 1997 and observed for at least 2 years. One hundred forty-one patients underwent planned neck dissection, and 18 patients received induction (17 patients) or concomitant (one patient) chemotherapy. RESULTS: Five-year local control rates, by tumor stage, were as follows: T1, 83%; T2, 81%; T3, 74%; and T4, 60%. Multivariate analysis revealed that local control was significantly influenced by tumor stage (P =.0001), fractionation schedule (P =.0038), and external beam dose (P =.0227). Local control after RT for early-stage cancers was higher for tonsillar fossa/posterior pillar cancers than for those arising from the anterior tonsillar pillar. Five-year cause-specific survival rates, by disease stage, were as follows: I, 100%; II, 86%; III, 82%; IVa, 63%; and IVb, 22%. Multivariate analysis revealed that cause-specific survival was significantly influenced by overall stage (P =.0001), planned neck dissection (P =.0074), and histologic differentiation (P =.0307). The incidence of severe late complications after treatment was 5%. CONCLUSION: RT alone or combined with a planned neck dissection provides cure rates that are as good as those after surgery and is associated with a lower rate of severe complications. (+info)Tonsillar lymphangiomatous polyps: a clinicopathologic series of 26 cases. (5/140)
BACKGROUND: Lymphangiomatous polyps are uncommon benign tumors of the tonsils. METHODS: Twenty-six cases of lymphangiomatous polyps diagnosed between 1980 and 1999 were retrieved from the files of the Otorhinolaryngic-Head and Neck Tumor Registry of the Armed Forces Institute of Pathology. Hematoxylin and eosin-stained slides were reviewed to characterize the histologic features of these tumors. Immunohistochemical stains were performed on 15 cases. Clinical follow-up data were obtained. RESULTS: The patients included 13 males and 13 females, ages 3 to 63 years (mean, 25.2 years). Patients experienced dysphagia, sore throat, and the sensation of a mass in the throat. Symptoms were present from a few weeks to years. The tonsillar masses were unilateral in all cases. Clinically, the lesions were frequently mistaken for a neoplasm (n = 18 patients). Grossly, all of the lesions were polypoid and measured 0.5 to 3.8 cm (mean, 1.6 cm). Histologically, the polyps were covered by squamous epithelium showing variable epithelial hyperplasia, dyskeratosis, and lymphocytic epitheliotropism. The masses showed a characteristic submucosal proliferation of small to medium-sized, endothelial-lined, lymph-vascular channels lacking features of malignancy. Collagen, smooth muscle, and adipose tissue were present in the stroma. Intravascular proteinaceous fluid and lymphocytes were noted. Immunohistochemical findings confirmed the endothelial origin of the vascular proliferation and a mixed lymphoid population. The differential diagnosis included fibroepithelial polyp, lymphangioma, juvenile angiofibroma, and squamous papilloma. In all patients with follow-up, complete surgical excision was curative (mean follow-up, 5.4 years; range, 1 mo to 14 years). CONCLUSIONS: We detail the clinical and pathologic features of tonsillar lymphangiomatous polyps. These tumors are uncommon and may clinically be mistaken for a malignant neoplasm. The characteristic histologic features should allow for its correct diagnosis and differentiation from similar appearing tonsillar lesions. (+info)Autoamputation of the tongue. (6/140)
Autoamputation is an uncommon phenomenon that has been reported for the fingers, toes, appendix, ovary, spleen, etc. Autoamputation of the tongue has never been reported. An elderly man with carcinoma of lateral pharyngeal wall and tonsil presented with an autoamputated tongue that was attached to the oral cavity with a thin band. The patient required detachment of the tongue and tracheostomy followed by radiotherapy for the primary tumour. (+info)Lymphangiectatic fibrolipomatous polyp of the palatine tonsil. (7/140)
A rare benign polypoid tumor of the right palatine tonsil is described in a 23 year old male. It contained dilated lymphatic channels surrounded by fibrous tissue and foci of mature fat. The features of this lesion add support to the hypothesis that benign tumors of tonsil may be hamartomas of tonsil rather than true neoplasms. The differential diagnosis of polypoid lesions of the tonsil is discussed. (+info)Bilateral carotid aneurysms secondary to radiation therapy. (8/140)
A patient was seen with symptomatic, rapidly expanding aneurysms that developed in both carotid arteries 4 years after bilateral radiation to the neck, left combined mandibular resection, and radical neck dissection. The presenting symptoms were pain and transient ischemic attacks of cerebrovascular insufficiency. The aneurysms were treated uneventfully be resection and vein-graft replacement at 15-day intervals. Microscopy demonstrated typical radiation changes. Effects of radiation on arteries are reviewed. (+info)Tonsillar neoplasms refer to abnormal growths or tumors that develop in the tonsils, which are two masses of lymphoid tissue located on either side of the back of the throat (oropharynx). These growths can be benign or malignant (cancerous), and their symptoms may include difficulty swallowing, sore throat, ear pain, and swollen lymph nodes in the neck.
Tonsillar neoplasms are relatively rare, but they can occur at any age. The most common type of malignant tonsillar neoplasm is squamous cell carcinoma, which accounts for about 90% of all cases. Other types of malignant tonsillar neoplasms include lymphomas and sarcomas.
The diagnosis of tonsillar neoplasms typically involves a physical examination, imaging studies such as CT or MRI scans, and sometimes a biopsy to confirm the type of tumor. Treatment options depend on the stage and location of the tumor, as well as the patient's overall health. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up care is essential to monitor for recurrence and manage any long-term effects of treatment.
Pancreatic neoplasms refer to abnormal growths in the pancreas that can be benign or malignant. The pancreas is a gland located behind the stomach that produces hormones and digestive enzymes. Pancreatic neoplasms can interfere with the normal functioning of the pancreas, leading to various health complications.
Benign pancreatic neoplasms are non-cancerous growths that do not spread to other parts of the body. They are usually removed through surgery to prevent any potential complications, such as blocking the bile duct or causing pain.
Malignant pancreatic neoplasms, also known as pancreatic cancer, are cancerous growths that can invade and destroy surrounding tissues and organs. They can also spread (metastasize) to other parts of the body, such as the liver, lungs, or bones. Pancreatic cancer is often aggressive and difficult to treat, with a poor prognosis.
There are several types of pancreatic neoplasms, including adenocarcinomas, neuroendocrine tumors, solid pseudopapillary neoplasms, and cystic neoplasms. The specific type of neoplasm is determined through various diagnostic tests, such as imaging studies, biopsies, and blood tests. Treatment options depend on the type, stage, and location of the neoplasm, as well as the patient's overall health and preferences.
Neoplasms are abnormal growths of cells or tissues in the body that serve no physiological function. They can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow growing and do not spread to other parts of the body, while malignant neoplasms are aggressive, invasive, and can metastasize to distant sites.
Neoplasms occur when there is a dysregulation in the normal process of cell division and differentiation, leading to uncontrolled growth and accumulation of cells. This can result from genetic mutations or other factors such as viral infections, environmental exposures, or hormonal imbalances.
Neoplasms can develop in any organ or tissue of the body and can cause various symptoms depending on their size, location, and type. Treatment options for neoplasms include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, among others.
Neoplasms: Neoplasms refer to abnormal growths of tissue that can be benign (non-cancerous) or malignant (cancerous). They occur when the normal control mechanisms that regulate cell growth and division are disrupted, leading to uncontrolled cell proliferation.
Cystic Neoplasms: Cystic neoplasms are tumors that contain fluid-filled sacs or cysts. These tumors can be benign or malignant and can occur in various organs of the body, including the pancreas, ovary, and liver.
Mucinous Neoplasms: Mucinous neoplasms are a type of cystic neoplasm that is characterized by the production of mucin, a gel-like substance produced by certain types of cells. These tumors can occur in various organs, including the ovary, pancreas, and colon. Mucinous neoplasms can be benign or malignant, and malignant forms are often aggressive and have a poor prognosis.
Serous Neoplasms: Serous neoplasms are another type of cystic neoplasm that is characterized by the production of serous fluid, which is a thin, watery fluid. These tumors commonly occur in the ovary and can be benign or malignant. Malignant serous neoplasms are often aggressive and have a poor prognosis.
In summary, neoplasms refer to abnormal tissue growths that can be benign or malignant. Cystic neoplasms contain fluid-filled sacs and can occur in various organs of the body. Mucinous neoplasms produce a gel-like substance called mucin and can also occur in various organs, while serous neoplasms produce thin, watery fluid and commonly occur in the ovary. Both mucinous and serous neoplasms can be benign or malignant, with malignant forms often being aggressive and having a poor prognosis.
Skin neoplasms refer to abnormal growths or tumors in the skin that can be benign (non-cancerous) or malignant (cancerous). They result from uncontrolled multiplication of skin cells, which can form various types of lesions. These growths may appear as lumps, bumps, sores, patches, or discolored areas on the skin.
Benign skin neoplasms include conditions such as moles, warts, and seborrheic keratoses, while malignant skin neoplasms are primarily classified into melanoma, squamous cell carcinoma, and basal cell carcinoma. These three types of cancerous skin growths are collectively known as non-melanoma skin cancers (NMSCs). Melanoma is the most aggressive and dangerous form of skin cancer, while NMSCs tend to be less invasive but more common.
It's essential to monitor any changes in existing skin lesions or the appearance of new growths and consult a healthcare professional for proper evaluation and treatment if needed.
Multiple primary neoplasms refer to the occurrence of more than one primary malignant tumor in an individual, where each tumor is unrelated to the other and originates from separate cells or organs. This differs from metastatic cancer, where a single malignancy spreads to multiple sites in the body. Multiple primary neoplasms can be synchronous (occurring at the same time) or metachronous (occurring at different times). The risk of developing multiple primary neoplasms increases with age and is associated with certain genetic predispositions, environmental factors, and lifestyle choices such as smoking and alcohol consumption.
Kidney neoplasms refer to abnormal growths or tumors in the kidney tissues that can be benign (non-cancerous) or malignant (cancerous). These growths can originate from various types of kidney cells, including the renal tubules, glomeruli, and the renal pelvis.
Malignant kidney neoplasms are also known as kidney cancers, with renal cell carcinoma being the most common type. Benign kidney neoplasms include renal adenomas, oncocytomas, and angiomyolipomas. While benign neoplasms are generally not life-threatening, they can still cause problems if they grow large enough to compromise kidney function or if they undergo malignant transformation.
Early detection and appropriate management of kidney neoplasms are crucial for improving patient outcomes and overall prognosis. Regular medical check-ups, imaging studies, and urinalysis can help in the early identification of these growths, allowing for timely intervention and treatment.
A "second primary neoplasm" is a distinct, new cancer or malignancy that develops in a person who has already had a previous cancer. It is not a recurrence or metastasis of the original tumor, but rather an independent cancer that arises in a different location or organ system. The development of second primary neoplasms can be influenced by various factors such as genetic predisposition, environmental exposures, and previous treatments like chemotherapy or radiation therapy.
It is important to note that the definition of "second primary neoplasm" may vary slightly depending on the specific source or context. In general medical usage, it refers to a new, separate cancer; however, in some research or clinical settings, there might be more precise criteria for defining and diagnosing second primary neoplasms.
Lingual tonsils
List of MeSH codes (C09)
List of MeSH codes (C07)
Fordyce spots
HPV-positive oropharyngeal cancer
Marginal zone B-cell lymphoma
Glossary of medicine
Anaerobic infection
Diffuse large B-cell lymphoma
Birt-Hogg-Dubé syndrome
List of MeSH codes (C04)
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Salivary Gland Neoplasms3
- Salivary gland neoplasms are rare and can pose complex diagnostic questions and management challenges to the Histopathologist and Surgeon respectively. (atpjournal.org)
- Salivary gland neoplasms constituted 2.1% of all neoplastic lesions seen in the study period. (atpjournal.org)
- Salivary gland neoplasms are rare with males being more likely to have malignant salivary gland tumors as compared to females. (atpjournal.org)
Tonsil2
- An ectopic tonsil is tonsillar tissue that develops in areas outside of these regions. (9lib.co)
- C090 Tonsillar fossa C091 Tonsillar pillar C098 Overlapping lesion of tonsil C099 Tonsil, NOS (excluding lingual tonsil C02.4) C100 Vallecula C102 Lateral wall of oropharynx C103 Posterior wall of oropharynx C104 Branchial cleft (site of neoplasm) C108 Overlapping lesion of oropharynx C109 Oropharynx, NOS **Note 1:** This schema is based on the UICC chapter *Malignant Melanoma of Upper Aerodigestive Tract,* pages 51-53. (cancer.gov)
Hypertrophy3
- Tonsillectomy is a treatment option for recurrent and chronic tonsillitis, especially in patients with tonsillar hypertrophy that causes obstructive sleep-disordered breathing . (amboss.com)
- Lymphoid Tissue Hypertrophy (tonsillar/adenoidal hypertrophy): Patients should have periodic examinations to rule out potential complications and receive appropriate treatment if necessary. (nih.gov)
- Common INCRELEX-related adverse reactions in clinical trials include: hypoglycemia, local and systemic hypersensitivity, tonsillar hypertrophy ( 6.1 ). (nih.gov)
Metastasis1
- 5. [Ultrasonography of cervical lymphatic metastasis in patients with laryngeal neoplasms]. (nih.gov)
Carcinoma7
- Human papillomavirus (HPV) in tonsillar carcinoma is correlated with favourable clinical outcome. (nih.gov)
- Here, p16(INK4A), in situ HPV DNA hybridisation (ISH) and HPVL1 capsid detection were evaluated in tonsillar carcinoma to predict the response to radiotherapy (RT) and prognosis. (nih.gov)
- P16(INK4a) overexpression was correlated to HPV in tonsillar carcinoma and is useful for predicting RT response and prognosis in tonsillar carcinoma patients. (nih.gov)
- The biomarkers of human papillomavirus infection in tonsillar squamous cell carcinoma-molecular basis and predicting favorable outcome. (nih.gov)
- Squamous cell carcinoma is a type of neoplasm that can affect lingual tonsils. (wikipedia.org)
- particularly HPV-16) in tonsillar squamous cell carcinoma has grown. (medscape.com)
- Case reports reported concurrent HPV-related oropharyngeal, tonsillar, unspecified HNSCC, laryngeal and nasopharyngeal carcinoma among couples. (biomedcentral.com)
Pillar1
- Lesions were detected in the tongue 4 and tonsillar pillar 2 . (bvsalud.org)
Human papillomavirus1
- Myeloid Cells Are Enriched in Tonsillar Crypts, Providing Insight into the Viral Tropism of Human Papillomavirus. (harvard.edu)
Malignant3
- A malignant neoplasm arising from the vascular tissue. (nih.gov)
- [ 8 ] When tonsillectomy is performed for asymptomatic tonsillar asymmetry, only 5% of patients will have malignant findings on pathology results. (medscape.com)
- The incidence of multiple primary malignant neoplasms increases with age and they are encountered more frequently nowadays than before owing to better diagnostic approaches. (biomedcentral.com)
Cancer3
- Fifty-one pre-treatment paraffin-embedded tonsillar cancer biopsies were analysed. (nih.gov)
- OSCC constitutes the 8th most frequent neoplasm in humans according to the worldwide cancer incidence ranking, and has been primarily associated with smoking and alcohol consumption [ 1 ]. (biomedcentral.com)
- There has also been suggested in the literature, that infection with the Human Pappilomavirus (HPV) is associated with oral cancer, especially with occurrences in the back of the mouth (oropharynx, base of tongue, tonsillar pillars and crypt, as well as the tonsils themselves) [ 2 ]. (biomedcentral.com)
Oropharynx2
- In all, 44,160 cases of potentially HPV-associated cancers of the oropharynx and oral cavity were identified, including 19,239 (43.6%) tonsillar, 16,964 (38.4%) base of tongue, and 7957 (18.0%) other oropharyngeal cancers. (elsevierpure.com)
- Major structures within the oropharynx include the tonsillar (faucial) arches, tonsils, vallecula, base of the tongue, soft palate, uvula, and posterior and lateral pharyngeal wall (within the confines of the axial planes outlined above). (medscape.com)
Laryngeal2
Tonsils2
- Lingual tonsils are located on posterior aspect of tongue which is supplied through: Lingual artery, branch of external carotid artery Tonsillar branch of facial artery Ascending and descending palatine arteries Ascending pharyngeal branch of external carotid artery Lingual tonsils are innervated by tonsillar nerves from the tonsilar plexus, formed by the glossopharyngeal and vagus nerves. (wikipedia.org)
- Asymmetry of the tonsils has traditionally been considered an indication for tonsillectomy in order to pathologically evaluate for potential neoplasm as the source of the asymmetry. (medscape.com)
Tongue2
- Here we report a rare case of bilateral symmetric ectopic oral tonsillar tissue observed on the ventral surface of the tongue and two other solitary cases arising from floor of the mouth along with a review of the literature. (9lib.co)
- Patients with head and neck primary cancers have increased propensity of having second cancers especially in patients with tongue, pyriform sinus, larynx, oral cavity and tonsillar cancers. (biomedcentral.com)
Lesions1
- Biopsy samples of tonsillar lesions may be best obtained through formal tonsillectomy, particularly if neoplasm is the concern. (medscape.com)
Cervical1
- Patients may also have tender, swollen cervical lymph nodes and tonsillar exudates . (amboss.com)
Primary1
- From the archives of the AFIP: primary vascular neoplasms of the spleen: radiologic-pathologic correlation. (nih.gov)
Chronic1
- Innate adaptive immune cell dynamics in tonsillar tissues during chronic SIV infection. (harvard.edu)
Tissue1
- These findings were suggestive of ectopic tonsillar tissue. (9lib.co)
Lung1
- Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA. (uchicago.edu)
Head2
- OSCC constitutes the major neoplasm of the head and neck region, exhibiting a quite aggressive nature, often leading to unfavorable prognosis. (biomedcentral.com)
- Extranodal hematopoietic neoplasms and mimics in the head and neck: an update[J]. Hum Pathol, 2015, 46(8):1079-1100. (sdu.edu.cn)
Structures1
- The neoplasm can also invade adjacent brainstem structures, including the cardiorespiratory centers of the fourth ventricular floor. (medscape.com)