White Muscle Disease

Muscular Diseases

Nutritional muscular dystrophy

Cerebral palsy

Muscle-eye-brain disease

Selenium deficiency

Danon disease

Lyme disease

Association of Internes and Medical Students

Ophthalmoparesis

Tuberculosis in China

Freshwater prawn farming

Batten disease

List of MeSH codes (C22)

Silver-Russell syndrome

Lesser kudu

Muscular system of the horse

Loeffler endocarditis

Lumpy skin disease

Nervous system disease

HSPB6

Kawasaki disease

Equine protozoal myeloencephalitis

Chronic obstructive pulmonary disease

Polyneuropathy in dogs and cats

Binswanger's disease

Pelizaeus-Merzbacher disease

Booboo Stewart

Glycogen storage disease type II

Double-muscled cattle

Scleroderma

Hematodinium

Weakness20

• Methotrexate administration may be started at the outset of severe disease (eg, moderate to severe weakness, manifestations of vasculopathy) or started if patients fail to respond to high-dose corticosteroids within 6 weeks. (medscape.com)
• While deterioration of skeletal muscles results in stiffness, weakness, and recumbency. (wikipedia.org)
• Idiopathic inflammatory myopathy is a term applied to a group of relatively rare diseases that present with the gradual onset of weakness of shoulder and pelvic girdle muscles. (hcplive.com)
• Although many complaints of weakness are purely subjective, the finding of objective muscle weakness indicates an underlying myopathic or neuropathic process. (hcplive.com)
• Muscle weakness is the chief complaint in patients with any of the idiopathic inflammatory myopathies. (hcplive.com)
• However, muscle weakness is a common symptom in many patients with other conditions, and the differential diagnosis for the complaint is extensive ( Table 2 ). (hcplive.com)
• Other diseases that may cause the insidious onset of muscle weakness include the muscular dystrophies, metabolic myopathies (glycogen and lipid storage diseases), and endocrine myopathies. (hcplive.com)
• Neuropathic diseases, such as amyotrophic lateral sclerosis and myasthenia gravis, also may result in the gradual onset of weakness. (hcplive.com)
• The acute onset of muscle weakness suggests a neuropathic or myopathic cause other than the idiopathic inflammatory myopathies. (hcplive.com)
• As a rule, myopathic weakness is symmetrical and occurs mostly in the proximal muscle groups of the pelvis, thighs, shoulders, and neck. (hcplive.com)
• Patients with inclusion body myositis provide an exception to the rule in that they may present with distal or asymmetrical muscle weakness. (hcplive.com)
• Both genetic and infectious diseases can result in skeletal muscle degeneration, inflammation, pain, and/or weakness. (nih.gov)
• The absence of correlation with age and the presence, in some patients, of severe respiratory insufficiency without severe limb girdle muscle weakness indicate that respiratory function should be monitored independently from the degree of peripheral muscle weakness. (ersjournals.com)
• The spectrum of this disease is wide and varies from a rapidly progressive infantile disease with cardiorespiratory insufficiency, which is usually fatal before 1 yr of age 1 , to a slowly progressive adult-onset disease with muscle weakness, respiratory insufficiency 1 , 2 and sleep-disordered breathing 3 . (ersjournals.com)
• These characteristics, and the likelihood that new treatments recently tested in infantile and juvenile Pompe's disease 7 - 10 will require evaluation in adult-onset disease, indicate a need for investigations into the relationships between respiratory muscle weakness and weakness in other muscles. (ersjournals.com)
• The Muscle Disease Section focuses its research on myositis, a rare family of autoimmune diseases in which the body's immune system attacks healthy muscle tissue, causing inflammation, weakness, fatigue, and pain in skeletal muscles. (nih.gov)
• When skeletal muscle is primarily affected, signs of muscle weakness, stiffness, and difficulty rising are seen. (merckvetmanual.com)
• Weakness, ataxia, and neurologic signs may be misinterpreted as lameness in diseases such as scrapie, listeriosis, and maedi visna. (merckvetmanual.com)
• Yellowing hair can also be an indication of certain diseases or disorders , such as inflammatory diseases that lead to skin rash and muscle weakness. (lovetoknow.com)
• Cystatin C is clearly superior to creatinine because it overcomes the major weakness of creatinine's inaccuracy in people with reduced muscle or limited activity. (va.gov)

Skeletal muscles1

• Symptoms in skeletal muscles range from moderate rigidity to visible discomfort when walking or failure to stand. (systemagility.com)

Infectious diseases4

• Thus, the zebrafish is a powerful system with which to ask questions about the etiology and mechanisms of muscle damage due to genetic and/or infectious diseases. (nih.gov)
• It can be difficult to clinically distinguish Ebola diseases symptoms from other infectious diseases such as malaria, typhoid fever and meningitis. (who.int)
• In support of improving patient care, this activity has been planned and implemented by Medscape, LLC and Emerging Infectious Diseases. (cdc.gov)
• NIAID supports basic and applied research to prevent, diagnose and treat infectious diseases such as HIV/AIDS and other sexually transmitted infections, influenza, tuberculosis, malaria and illness from potential agents of bioterrorism. (scienceblog.com)

Affects10

• a congenital form that affects the heart muscle and a delayed form that is associated with the muscle of the heart or the skeleton. (systemagility.com)
• Inclusion body myositis, which typically affects the muscles of older adults. (nih.gov)
• Ebola diseases (EBOD) are rare, but severe and often fatal viral diseases that affects humans and other primates. (who.int)
• Wolff-Parkinson-White syndrome affects 1 to 3 in 1,000 people worldwide. (nih.gov)
• Adult-onset Still's disease (AOSD) is an inflammatory condition that affects multiple organs. (nih.gov)
• Fur- without diabetes, heart disease in diabetic individuals ther studies are needed to determine the role of insu- appears earlier in life, affects women almost as often lin in the risk of cardiovascular disease. (nih.gov)
• Scientists discovered how a mislocated protein implicated in several neurodegenerative diseases affects another protein that's needed for normal nerve cell functioning. (nih.gov)
• Akoya oyster disease affects oysters more than one year old, including juvenile, adult and seeded oysters. (thefishsite.com)
• HGA is considered an emerging infectious disease, and Dr. Borjesson is working to understand how it affects blood cells - and neutrophils in particular. (scienceblog.com)
• The parents and others who joined the protest wore white t-shirts and badges with 'Save Our Sons' written on them, as the disease mainly affects boys. (glamsham.com)

Autoimmune diseases18

• Autoimmune diseases. (clevelandclinic.org)
• Simply put, autoimmune diseases are conditions where the body's immune system attacks its own tissues rather than a foreign molecule like bacteria, and they are a huge problem both in this country and worldwide. (drhyman.com)
• But there are many more autoimmune diseases that affect the nervous system, joints and muscles, skin, endocrine gland, and heart. (drhyman.com)
• If you collectively take all the autoimmune diseases together, combined, it's more people than have cancer, heart disease, or diabetes combined. (drhyman.com)
• In a post on her website, Carrie Ann Conversations , Inaba talked about how she lives with several autoimmune diseases, including Sjogren's syndrome, lupus, fibromyalgia , rheumatoid arthritis, "and I have the markers for antiphospholipid syndrome, which can lead to blood clots. (medpagetoday.com)
• Autoimmune diseases can affect almost any part of the body. (medpagetoday.com)
• Some of the more common autoimmune diseases include type 1 diabetes, rheumatoid arthritis , systemic lupus erythematosus, multiple sclerosis , and inflammatory bowel disease . (medpagetoday.com)
• Overall, autoimmune diseases are common, affecting more than 23.5 million Americans. (medpagetoday.com)
• Some autoimmune diseases are rare, while others, such as Hashimoto's disease, affect many people. (medpagetoday.com)
• Women of childbearing age -- More women than men have autoimmune diseases, which often start during their childbearing years. (medpagetoday.com)
• People with a family history -- Some autoimmune diseases run in families, such as lupus and multiple sclerosis. (medpagetoday.com)
• It is also common for different types of autoimmune diseases to affect different members of a single family. (medpagetoday.com)
• People who are around certain things in the environment -- Certain events or environmental exposures may cause some autoimmune diseases or make them worse. (medpagetoday.com)
• Sunlight, chemicals such as solvents, and viral and bacterial infections are linked to many autoimmune diseases. (medpagetoday.com)
• People of certain races or ethnic backgrounds -- Some autoimmune diseases are more common or affect certain groups of people more severely. (medpagetoday.com)
• Most autoimmune diseases cause inflammation. (medpagetoday.com)
• Many autoimmune diseases affect more than one part of the body. (medpagetoday.com)
• Many autoimmune diseases cause generalized symptoms as well, such as fatigue, dizziness, weight loss or gain, or low-grade fever. (medpagetoday.com)

Severe7

• For refractory or severe disease, pulse therapy with intravenous methylprednisolone is used at a dose of 30 mg/kg, with a maximum dose of 1 g daily for 3 days with efficacy. (medscape.com)
• Chronic kidney disease (CKD)-or chronic renal failure (CRF), as it was historically termed-is a term that encompasses all degrees of decreased kidney function, from damaged-at risk through mild, moderate, and severe chronic kidney failure. (medscape.com)
• IRD has some residual perixisome function, resulting in less severe disease than in Zellweger syndrome. (nih.gov)
• InLighta Biosciences, which Dr. Yang founded in 2014 in Atlanta, Georgia, began by focusing on diagnosing liver disease, which causes severe fibrosis or scarring of the tissue. (nih.gov)
• This test is used to study the muscles (severe muscle pain and heart disease). (showfranckmuller.com)
• For instance, type 1 diabetes is more common in white people, while lupus is most severe for Black and Hispanic people. (medpagetoday.com)
• Weight loss, muscle loss, and anorexia are common in patients with severe and very severe COPD. (bmj.com)

Coronary artery2

• In 927 biologically unrelated Caucasian patients with coronary artery disease it was investigated whether the NcoI restriction fragment length polymorphism of the muscle-specific creatine kinase (CKMM) gene is associated with aerobic power and with the response to physical training. (nih.gov)
• The CAREGENE study: polymorphisms of the beta1-adrenoceptor gene and aerobic power in coronary artery disease. (nih.gov)

Selenium12

• The prime cause of White Muscle Disease (WMD) is a deficiency of selenium and/or Vitamin E. (systemagility.com)
• White muscle disease-affected cattle obtained a vaccine for sterile emulsion with sodium selenite and vitamin E. SC or IM, 1 mg selenium and 50 mg (68 IU) of vitamin E per 18 kg (40 lbs) of body weight can be administered. (systemagility.com)
• Cows are given 15 mg of selenium, usually sodium selenite, four weeks before calving to avoid white muscle disease within four weeks after their birth. (systemagility.com)
• Nutritional Muscular Dystrophy (Nutritional Myopathy or White Muscle Disease) is a disease caused by a deficiency of selenium and vitamin E in dietary intake. (wikipedia.org)
• 1993. White Muscle Disease and Other Selenium-Responsive Diseases of Livestock. (wikipedia.org)
• Nutritional myodegeneration (NMD) is an acute, degenerative disease of cardiac and skeletal muscle caused by a dietary deficiency of selenium or vitamin E in young, rapidly growing calves, lambs, and kids. (merckvetmanual.com)
• DESCRIPTION BO-SE (selenium, vitamin E) is an emulsion of selenium-tocopherol for the prevention and treatment of white muscle disease (Selenium-Tocopherol Deficiency) syndrome in calves, lambs, and ewes, and as an aid in the prevention and treatment of Selenium-Tocopherol Deficiency in sows and weanling pigs. (nih.gov)
• In sows and weanling pigs, as an aid in the prevention and treatment of diseases associated with Selenium-Toco pherol deficiency, such as hepatic necrosis, mulberry heart disease, and white muscle disease. (nih.gov)
• Even in selenium deficient areas there are other disease conditions which produce similar clinical signs. (nih.gov)
• For example, too much selenium causes alkali disease, or seleniosis, while too little may cause muscle problems or white muscle disease. (americanfarriers.com)
• Vitamin E & Selenium supplements are commonly given to horses that tie up, have post workout issues or to pregnant mares to prevent white muscle disease in their foals. (marystack.com)
• White muscle disease in foals: Focus on selenium soil content. (wur.nl)

Horse's2

• AST and CK The horse's muscle enzymes are some of the most important performance-related chemistries to evaluate, he said. (thehorse.com)
• The Quarter Horse's well-muscled hindquarters add to their impressive stature. (holistapet.com)

Deficiency4

• Pompe's disease, also named acid maltase deficiency or glycogen storage disease type II, is an autosomal recessive disorder characterised by a deficiency in the lysosomal enzyme acid α-glucosidase (GAA). (ersjournals.com)
• If you have something known as `glucose-6-phosphate dehydrogenase deficiency' (a rare hereditary disease). (who.int)
• A deficiency causes white muscle disease (muscular dystrophy), poor growth in lambs, calves and fawns, low fertility in ewes, and poor milk production in cattle. (teara.govt.nz)
• The researchers point out that African Americans have a much higher incidence of fatal heart disease (37 per cent higher among men and 63 per cent higher among women) than do whites and speculate that this could be due, at least in part, to a vitamin E deficiency. (yourhealthbase.com)

20211

• The government has identified hundreds of rare diseases under the National Policy for Rare Diseases 2021 (NPRD). (glamsham.com)

Muscular7

• Muscular strength training increases muscle mass (4,5) and improves the physical function (6,7) of adults throughout the lifespan and may decrease the likelihood of developing sarcopenia (the loss of skeletal muscle mass and function). (cdc.gov)
• A detailed family history may suggest the presence of an inherited muscle disorder, such as a muscular dystrophy or metabolic myopathy. (hcplive.com)
• Duchenne muscular dystrophy (DMD) is the most common congenital muscle disease. (nih.gov)
• Muscle power of the quadriceps femoris, hip flexors and gluteus medius on both sides of the body was graded using the Modified Medical Research Council (MMRC) scale, which has been used in muscle diseases, such as Duchenne muscular dystrophy 14 . (ersjournals.com)
• This image depicts a skeletal muscle tissue specimen, which had been harvested from a person with a fatal case of Duchenne muscular dystrophy (DMD), also known as pseudohypertrophic muscular dystrophy. (cdc.gov)
• These supplements may also benefit people with muscular diseases and those recovering from knee surgery. (consumerlab.com)
• New Delhi, March 24 (IANS) The parents of children suffering from Duchenne Muscular Dystrophy (DMD), a fatal genetic disease, gathered at the Jantar Mantar on Friday to raise awareness about the disease and register their dissent against the government's apathy. (glamsham.com)

Liver6

• Laboratory findings include low white blood cell and platelet counts and elevated liver enzymes. (who.int)
• Business Technology Transfer Research (STTR) program, is seeking to change that, starting with patients with liver disease. (nih.gov)
• We can detect changes at stage 2 not stage 4 for fibrosis in liver disease," says Yang. (nih.gov)
• According to the Centers for Disease Control and Prevention, approximately 4.5 million U.S. adults have been diagnosed with liver disease. (nih.gov)
• Heavy alcohol use is a risk factor for developing liver disease. (nih.gov)
• They also point out that vitamin E deficiencies have been linked to diabetes, immune disorders, AIDS, muscle damage in exercise, Parkinson's disease, eye diseases, and lung and liver diseases. (yourhealthbase.com)

Clinical12

• Because of the rarity of the disease, patients with JDM should be transferred to a tertiary care center for experienced clinical care in the initial course of the disease and for periodic follow-up. (medscape.com)
• Understanding the epidemiology, clinical presentation, diagnostic techniques, and treatment options is important to reduce the significant morbidities related to these disease processes. (hcplive.com)
• The diagnosis of an idiopathic inflammatory myopathy is made by finding a combination of a typical clinical presentation in association with elevated levels of enzymes of muscle origin, myopathic changes on electromyography, edema in muscle on MRI, and characteristic muscle histopathology. (hcplive.com)
• The objective of the present study was to prospectively evaluate relationships linking age, respiratory function and locomotor function in 29 outpatients with late-onset Pompe's disease and to retrospectively determine clinical outcomes. (ersjournals.com)
• The objectives of the present study were to evaluate relationships linking age, respiratory function and locomotor function, and to assess clinical outcomes in the adult form of Pompe's disease. (ersjournals.com)
• This study of inflammatory muscle diseases-polymyositis and dermatomyositis and related disorders-will examine what causes these diseases and describe the clinical features (signs and symptoms) associated with them. (nih.gov)
• Clinical research uses human volunteers to help researchers learn more about a disorder and perhaps find better ways to safely detect, treat, or prevent disease. (nih.gov)
• Olujohungbe A, Howard J. The clinical care of adult patients with sickle cell disease. (medscape.com)
• The goal of the program is to advance understanding of the expression of heart disease in this population through exploitation of modern methods and approaches to molecular biology, cellular and organ physiology, and clinical practice. (nih.gov)
• IMACS recommends these core set measures be included in all myositis therapeutic trials and clinical studies that assess disease activity in patients with myositis. (nih.gov)
• If you have high muscle enzymes in the chemistry report and the clinical signs (stiffness, shortened stride, and painful muscles after racing) to go with it, then you can be fairly certain a myopathy is causing the poor performance on that day," Divers said. (thehorse.com)
• Existing intra-operative techniques based on white light cystoscopy (WLC) lacks the ability to provide histopathologic information, which is essential for early detection, diagnosis and prognosis, while other developments such as blue light photodynamic diagnosis have lacked the specificity/sensitivity for widespread clinical adoption. (imperial.ac.uk)

Genetic4

• Infantile Refsum disease (IRD) is a medical condition within the Zellweger spectrum of perixisome biogenesis disorders (PBDs), which are inherited genetic disorders that damage the white matter of the brain and affect motor movements. (nih.gov)
• ALS and FTD patients have long participated in genetic studies looking for changes in genes that might contribute to risk for disease," explains Dr. Thomas Cheever, program director at NINDS. (nih.gov)
• Marked increases in AST and CK activity in racehorses are most commonly due to recurrent exertional rhabdomyolysis (RER), a genetic muscle disorder found in 5-10% of Thoroughbreds and Standardbreds. (thehorse.com)
• however, studies indicate that these diseases likely result from interactions between genetic and environmental factors. (medpagetoday.com)

Inflammation2

• Alternatively, Alzheimer's disease and sarcopenia may share an underlying mechanism, such as inflammation or changes in the process of building tissue. (sciencedaily.com)
• It is used to treat a wide range of bacterial infections in goats, including pneumonia, enteritis (inflammation of the intestines) caused by coccidia and salmonella bacteria, respiratory disease caused by Pasteurella bacteria, rhinitis (inflammation of the nose), udder edema (swelling of the udder), mastitis (inflammation of the mammary glands) and metritis (infection in the uterus). (justagric.com)

Environmental exposures2

• Understand how environmental exposures, including medications such as statins and cancer immunotherapies, can trigger autoimmune muscle disease. (nih.gov)
• NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)

Myopathy3

• Nutritional myopathy of calves is also known as white muscle disease. (systemagility.com)
• Individual diseases included under the term "idiopathic inflammatory myopathy" are polymyositis and dermatomyositis, as well as myositis associated with neoplastic disease, myositis associated with collagen-vascular disease, and inclusion body myositis. (hcplive.com)
• myopathy associated with collagen-vascular disease occurs at the age that is associated with the particular collagen-vascular disease that is present. (hcplive.com)

Lambs2

• In lambs, the disease typically occurs between 3 and 8 weeks of age, but may occur in older lambs as well. (wikipedia.org)
• White Muscle Disease in Lambs: What Is It and How to Prevent It? (morningchores.com)

Calves3

• The calves which suffer from these diseases are expected to die within a week. (systemagility.com)
• In dairy breeds, the disease may occur in calves between birth and 4 months of age. (wikipedia.org)
• In calves, muscles in upper portion of the front legs and the hind legs are degraded, causing the animal to have a stiff gait and it may have difficulty standing. (wikipedia.org)

Symptoms12

• Unintended weight loss often occurs among individuals with Alzheimer's disease and frequently begins prior to memory loss or other cognitive symptoms, according to background information in the article. (sciencedaily.com)
• Ebola diseases symptoms can be sudden. (who.int)
• A person infected with an Ebolavirus cannot spread the disease until they develop symptoms. (who.int)
• When Do Symptoms of Adult-onset Still disease Begin? (nih.gov)
• Symptoms of this disease may start to appear as an Adult and as an Older Adult. (nih.gov)
• The age symptoms may begin to appear differs between diseases. (nih.gov)
• The symptoms from some diseases may begin at any age. (nih.gov)
• The types of symptoms experienced, and their intensity, may vary among people with this disease. (nih.gov)
• HGA typically causes mild symptoms that include fever, muscle aches and nausea. (scienceblog.com)
• Keep up with your dosages until symptoms subside and then begin using smaller amounts on a regular basis as a preventative measure against coccidiosis or other intestinal diseases that may invade the goat's system while they are stressed through illness or pregnancy - which often includes giving birth. (justagric.com)
• Making a diagnosis of a specific autoimmune disease can be difficult, as many symptoms are the same for other types of health problems. (medpagetoday.com)
• The Centers for Disease Control (CDC) describes ME/CFS as a distinct disorder with specific symptoms and physical signs. (medlineplus.gov)

Heart26

• Recommendations for physical activity from both the American College of Sports Medicine/American Heart Association (1) and the US Department of Health and Human Services (DHHS) (2) emphasize regular participation in muscle strengthening activities for adults. (cdc.gov)
• The heart will show white, chalky sub-endochondral plaques that are most visible in the left ventricle upon inspection after death. (systemagility.com)
• The condition can affect the skeletal as well as the heart muscles. (systemagility.com)
• Since there are no specific blood tests for myocarditis, these markers can be a sign of injury to the heart muscle. (nih.gov)
• These antibodies can attack your heart muscle. (nih.gov)
• Wolff-Parkinson-White syndrome is a condition characterized by abnormal electrical pathways in the heart that cause a disruption of the heart's normal rhythm (arrhythmia). (nih.gov)
• People with Wolff-Parkinson-White syndrome are born with an extra connection in the heart, called an accessory pathway, that allows electrical signals to bypass the atrioventricular node and move from the atria to the ventricles faster than usual. (nih.gov)
• Complications of Wolff-Parkinson-White syndrome can occur at any age, although some individuals born with an accessory pathway in the heart never experience any health problems associated with the condition. (nih.gov)
• Wolff-Parkinson-White syndrome often occurs with other structural abnormalities of the heart or underlying heart disease. (nih.gov)
• Wolff-Parkinson-White syndrome is the most frequent cause of this abnormal heart rhythm in the Chinese population, where it is responsible for more than 70 percent of cases. (nih.gov)
• Some people with these variants also have features of hypertrophic cardiomyopathy, a form of heart disease that enlarges and weakens the heart (cardiac) muscle. (nih.gov)
• Researchers are uncertain how PRKAG2 gene variants lead to the development of Wolff-Parkinson-White syndrome and related heart abnormalities. (nih.gov)
• Based on the 1989 U.S. National Health Inter- ter 7, adults with diabetes are more likely than those view Survey (NHIS), 3% of men and women without diabetes to have hypert en sion and age 18-44 years who reported having diabetes dyslipidemia (low levels of high-density lipoprotein, also reported having ischemic heart disease. (nih.gov)
• The most common cause creased risk of heart disease associated with diabetes of death in adults with diabetes is coronary heart appears to be independent of these factors. (nih.gov)
• Since hospitals may be there because they have another then, publications on the relation between diabetes condition in addition to clinically recognized diabe- and heart disease have improved in both quantity and tes). (nih.gov)
• Unfortunately the criteria for ischemic (also called of the population for both heart disease and diabetes, coronary) heart disease have been less well stand- prevalence studies are also subject to ascertainment ardized and still vary from study to study. (nih.gov)
• Further, the bias because diabetes may be more often sought in most definitive diagnostic methods, such as coronary persons with heart disease and vice versa. (nih.gov)
• Applicants should select one of three themes, Sudden Cardiac Death, Microvascular Disease, or Diabetic Heart Disease as the focusof their applications. (nih.gov)
• The goal of this initiative is to foster an interdisciplinary study of issues surrounding the expression of heart disease in Blacks. (nih.gov)
• This RFA, Specialized Centers of Research in Ischemic Heart Disease in Blacks, is related to the priority areas of heart disease and stroke, and diabetes and chronic disabling diseases. (nih.gov)
• Upon initiation of the program, the Division of Heart and Vascular Diseases will sponsor periodic meetings to encourage exchange of information among investigators who participate in this program, and to stimulate collaboration. (nih.gov)
• Growing rapidly, soon it engulfs every muscle of the body, including the heart and lungs. (glamsham.com)
• Shlipak and his team found that elevated blood levels of cystatin C accurately predict higher risks of heart disease, stroke, and death among elderly people with no known kidney problems. (va.gov)
• however, the response of skeletal muscle, as opposed to the heart, has been attenuated. (duke.edu)
• Exogenous gene delivery to alter the function of the heart is a potential novel therapeutic strategy for treatment of cardiovascular diseases such as heart failure (HF). (duke.edu)
• Physical examination may demonstrate hypoxia, use of accessory muscles, paradoxical rib movements, distant heart sounds, lower-extremity edema and hepatomegaly secondary to cor pulmonale, and asterixis secondary to hypercapnia. (bmj.com)

20231

• Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: 2023 report [internet publication]. (bmj.com)

Disorder1

• To compare prevalences of self-reported comorbid headache, neck, back, and joint pains in respondents with temporomandibular joint and muscle disorder (TMJMD)-type pain in the 2000-2005 US National Health Interview Survey (NHIS), and to analyze these self-reported pains by gender and age for Non-Hispanic (NH) Whites (Caucasians), Hispanics, and NH Blacks (African Americans). (nih.gov)

Abnormal3

• a disease that causes episodes of depression, episodes of mania, and other abnormal moods). (nih.gov)
• The magnetism of the dye enhances the images taken by the MRI, revealing the differences between healthy and abnormal tissues through black and white images. (nih.gov)
• But in certain neurodegenerative diseases, TDP-43 forms abnormal clumps outside of the nucleus. (nih.gov)

Occur5

• Although respiratory muscle involvement is rarely inaugural 5 , 6 , it may occur early in the course of the disease and may cause death. (ersjournals.com)
• Graft-versus-host disease (GVHD) is a life-threatening complication that can occur after certain stem cell or bone marrow transplants . (medlineplus.gov)
• We observed a direct correlation between whole-brain volume (an estimate of brain atrophy) and lean mass, suggesting that brain atrophy and loss of muscle mass may co-occur," the authors write. (sciencedaily.com)
• When deficiencies occur, this results in a condition called white muscle disease . (hobbyfarms.com)
• More than 80 diseases occur as a result of the immune system attacking the body's own organs, tissues, and cells. (medpagetoday.com)

Rare diseases4

• With an estimated incidence of only 5 cases per million adults, 1 the idiopathic inflammatory myopathies are rare diseases. (hcplive.com)
• Questions about rare diseases? (nih.gov)
• Many rare diseases have limited information. (nih.gov)
• The parents demanded that within the rare diseases category, a separate category should be made for 'life-threatening diseases' to prioritise help and support for them. (glamsham.com)

Respiratory6

• Cyclophosphamide at a dose of 0.5-1 g/m 2 may be given with bladder protection on a monthly basis and adjusted for leukopenia for patients with significant morbidity such as skin or GI ulcerations, respiratory disease, or both. (medscape.com)
• If the cardiac muscles are impaired the animal may exhibit signs of respiratory distress. (wikipedia.org)
• The disease may also present in the form of respiratory distress. (wikipedia.org)
• When cardiac muscle is primarily affected, animals may be found in respiratory distress, have cardiac arrhythmias, or be found dead. (merckvetmanual.com)
• If the respiratory muscles are affected, the animal may show respiratory distress and evidence of increased abdominal effort when breathing. (merckvetmanual.com)
• An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease. (bmj.com)

Prevention6

• Centers for Disease Control and Prevention. (cdc.gov)
• The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
• HEALTHY PEOPLE 2000 The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2000," a PHS-led national activity for setting priority areas. (nih.gov)
• This product is a must before breeding and before lambing to aid in prevention of white muscle disease and to boost reproduction. (premier1supplies.com)
• Researchers at the Centers for Disease Control and Prevention have just released the results of a study aimed at determining vitamin E status among Americans. (yourhealthbase.com)
• Some 362 U.S. cases were reported to the Centers for Disease Control and Prevention in 2003. (scienceblog.com)

Chronic7

• Horses may also develop a more chronic delayed form of the disease called Neuroaxonal Dystrophy (NAD) or Equine Degenerative Myeloencephalopathy (EDM). (wikipedia.org)
• The evaluation consisted of an interview regarding occupational activities, ability to swallow without difficulty, ability to control urination and presence of chronic pain ( e.g. in the back, neck or muscles). (ersjournals.com)
• She reports a chronic morning cough productive of white sputum, which has increased over the past 2 days. (bmj.com)
• [1] Global Initiative for Chronic Obstructive Lung Disease (GOLD). (bmj.com)
• Chronic obstructive pulmonary disease in over 16s: diagnosis and management. (bmj.com)
• Can moderate chronic obstructive pulmonary disease be diagnosed by historical and physical findings alone? (bmj.com)
• Chronic obstructive pulmonary disease and the risk of 12 cardiovascular diseases: a population-based study using UK primary care data. (bmj.com)

Diagnosis2

• Radiology, or imaging as it's often called, by definition is the science of high-energy radiation for the diagnosis and treatment of disease. (postindependent.com)
• X-rays are commonly used to diagnosis fractures and some lung disease. (postindependent.com)

Typically3

• Skeletal muscle lesions associated with white muscle disease delay are typically bilateral symmetric and can affect one or more muscle growth. (systemagility.com)
• However, while younger patients with CKD typically experience progressive loss of kidney function, 30% of patients over 65 years of age with CKD have stable disease. (medscape.com)
• Sarcopenia -- the loss of muscle mass typically associated with aging -- is most strongly associated with reductions in physical activity, the authors note. (sciencedaily.com)

Patients16

• Patients should be followed on a regular basis, with monitoring of muscle enzymes and muscle strength every 3-6 months. (medscape.com)
• In total, 29 patients with late-onset Pompe's disease were investigated prospectively as part of routine follow-up. (ersjournals.com)
• Lean mass -- the weight of an individual's bones, muscles and organs without body fat -- appears to decline among patients with Alzheimer's disease, according to a new report. (sciencedaily.com)
• Lean mass -- the weight of an individual's bones, muscles and organs without body fat -- appears to decline among patients with Alzheimer's disease, according to a report in the April issue of Archives of Neurology , one of the JAMA/Archives journals. (sciencedaily.com)
• After controlling for sex, lean mass was reduced among patients with Alzheimer's disease compared with healthy controls. (sciencedaily.com)
• During the 2018-2020 Ebola virus disease (EVD) outbreak caused by Zaire ebolavirus in the Democratic Republic of the Congo, the first-ever multi-drug randomized control trial was conducted to evaluate the effectiveness and safety of drugs used in the treatment of EVD patients under an ethical framework developed in consultation with experts in the field and the DRC. (who.int)
• Acetaminophen is the drug of choice for pain in patients with documented hypersensitivity to aspirin or NSAIDs, with upper GI disease, or who are taking oral anticoagulants. (medscape.com)
• The National Institutes of Health advises that optimal care for patients with sickle cell disease (SCD), including preventive care, is best achieved through treatment in clinics that specialize in the care of SCD. (medscape.com)
• If patients with SCD crisis are being transported by emergency medical services (EMS), they should receive supplemental oxygen and intravenous hydration en route to the hospital. (medscape.com)
• Normally, MRI contrast dyes are made of small, heavy magnetic metal and is not well-tolerated by all patients, especially those with kidney disease. (nih.gov)
• She adds that with the new technology, it is possible to not only visualize and diagnose fibrotic tissue, but to monitor and treat disease progression in patients over time. (nih.gov)
• Patients with lower extremity peripheral artery disease (PAD) have decreased mobility, which is not fully explained by impaired blood supply to the lower limb. (uky.edu)
• Bladder cancer patients with superficial tumours are associated with a significantly higher risk of developing local recurrence and disease progression (70%), necessitating regular endoscopic surveillance, as well as a risk of superficial disease (30%) progressing into the more significant muscle-invasive state. (imperial.ac.uk)
• Elaborating on this life-threatening diseases, Sheffali Gulati, head of pediatric neurology at AIIMS Delhi, said, "The government can provide financial support to these patients in procuring and importing these newer medications. (glamsham.com)
• We think patients need the cystatin C test for everyday decision-making, and using it may lead to earlier detection of kidney disease and fewer adverse events from kidney disease. (va.gov)
• Some patients report chest tightness, which often follows exertion and may arise from intercostal muscle contraction. (bmj.com)

Kidney8

• Kidney disease is the ninth leading cause of death in the United States. (medscape.com)
• The Kidney Disease Outcomes Quality Initiative (KDOQI) of the National Kidney Foundation (NKF) established a definition and classification of CKD in 2002. (medscape.com)
• [ 2 ] The KDOQI and the international guideline group Kidney Disease Improving Global Outcomes (KDIGO) subsequently updated these guidelines. (medscape.com)
• [ 3 ] More specifically, the guidelines recommended the inclusion of estimated GFR and albuminuria levels when evaluating risks for overall mortality, cardiovascular disease, end-stage kidney failure, acute kidney injury, and the progression of CKD. (medscape.com)
• Drs. Michelle Estrella and Michael Shlipak of the San Francisco VA believe the cystatin C test is much more accurate in detecting kidney disease than the one that has long been used in standard medical practice, the creatinine test. (va.gov)
• More than 15 years ago, Dr. Michael Shlipak began studying a test he believed to be much more accurate in detecting kidney disease than the one in standard practice for decades. (va.gov)
• Fast forward to today, and the creatinine test is still the predominant choice among nephrologists, who treat kidney disease. (va.gov)
• They have also spoken to VA decision-makers about the test, including Dr. Michael Icardi, VA's national director of pathology and laboratory medicine services, and Dr. Susan Crowley, VA's national program director for kidney disease and analysis. (va.gov)

Viral diseases1

• Foot-and-Mouth Disease in Animals Foot-and-mouth disease is one of the world's most economically important viral diseases of livestock. (merckvetmanual.com)

Risk of cardiovascular disease1

• CKD is associated with an increased risk of cardiovascular disease and end-stage renal disease (ESRD). (medscape.com)

Necrosis1

• On necropsy, muscles are pale with areas of necrosis and edema evidenced as white streaks. (wikipedia.org)

Systemic1

• The condition can also be called systemic exertional intolerance disease (SEID). (medlineplus.gov)

Bacterial1

• New research on a bacterium that can survive encounters with specific immune system cells has strengthened scientists' belief that these plentiful white blood cells, known as neutrophils, dictate whether our immune system will permit or prevent bacterial infections. (scienceblog.com)

Polymyositis1

• These diseases include polymyositis and dermatomyositis, as well as myositis associated with neoplastic disease, myositis associated with underlying collagen-vascular disease, and inclusion body myositis. (hcplive.com)

Fatal1

• IRD is a fatal disease, but some children will survive into their teens and twenties, and possibly even beyond. (nih.gov)

Glycogen1

• Studies indicate that changes in AMP-activated protein kinase activity allow a complex sugar called glycogen to build up abnormally within cardiac muscle cells. (nih.gov)

Black and Hispanic1

• Low back pain was higher in Black and Hispanic females across the age span, and higher among non-White males after age 60. (nih.gov)

Cardiac muscle cells1

• Damage to cardiac muscle cells and Purkinje fibers is the result of this disease. (systemagility.com)

Immune system2

• These data suggest that the immune system may contribute to muscle pathology. (nih.gov)
• Neutrophils, which make up about 60 percent of all white blood cells, are the largest cellular component of the human immune system - billions exist inside each human. (scienceblog.com)

Pompe3

• Adjunctive β2-agonists reverse neuromuscular involvement in murine Pompe disease. (duke.edu)
• Pompe disease has resisted enzyme replacement therapy with acid α-glucosidase (GAA), which has been attributed to inefficient cation-independent mannose-6-phosphate receptor (CI-MPR) mediated uptake. (duke.edu)
• Enhanced efficacy of enzyme replacement therapy in Pompe disease through mannose-6-phosphate receptor expression in skeletal muscle. (duke.edu)

Causes White Muscle Disease1

• What Causes White Muscle Disease? (systemagility.com)

Complications3

• Influenza A and B viruses are frequently associated with muscle complications, especially in children. (nih.gov)
• However, roles of the immune response in DMD and Influenza muscle complications are not well understood. (nih.gov)
• The goals of treatment are symptom control and management of disease complications. (medscape.com)

Disorders1

• Although adult Refsum disease and IRD have similar names, they are separate disorders caused by different gene defects. (nih.gov)

Cattle1

• Young, rapidly growing animals usually are affected, although the disease has also been reported in yearling and adult cattle. (merckvetmanual.com)

Adult1

• Mechanical ventilation and tracheostomy may improve vital capacity and should, therefore, be taken into account when evaluating treatments for the adult form of Pompe's disease. (ersjournals.com)