Infections with bacteria of the species YERSINIA PSEUDOTUBERCULOSIS.
A human and animal pathogen causing mesenteric lymphadenitis, diarrhea, and bacteremia.
Infections with bacteria of the genus YERSINIA.
A species of gram-positive, asporogenous bacteria that was originally isolated from necrotic areas in the kidney of a sheep. It may cause ulcerative lymphangitis, abscesses, and other chronic purulent infections in sheep, horses, and other warm-blooded animals. Human disease may form from contact with infected animals.
Infections with bacteria of the genus CORYNEBACTERIUM.
A species of the genus YERSINIA, isolated from both man and animal. It is a frequent cause of bacterial gastroenteritis in children.
A genus of gram-negative, facultatively anaerobic rod- to coccobacillus-shaped bacteria that occurs in a broad spectrum of habitats.
The etiologic agent of PLAGUE in man, rats, ground squirrels, and other rodents.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
An acute infectious disease caused by YERSINIA PESTIS that affects humans, wild rodents, and their ectoparasites. This condition persists due to its firm entrenchment in sylvatic rodent-flea ecosystems throughout the world. Bubonic plague is the most common form.
Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.

Seroepidemiologic study on the occurrence of antibodies against Yersinia enterocolitica and Yersinia pseudotuberculosis in urban and rural population of the Lublin region (eastern Poland). (1/129)

The aim of this study was to assess the seroprevalence of antibodies against Yersinia in the rural and urban population and to determine the frequency of particular serotypes of Yersinia enterocolitica and Yersinia pseudotuberculosis. 472 sera were examined, 257 of rural inhabitants and 215 of urban inhabitants. The survey was carried out by passive hemagglutination test with the antigens of Yersinia serotypes considered pathogenic for humans: Y. enterocolitica 03, 05, 06, 08, 09 and Y. pseudotuberculosis I and III. In the examined rural population positive reactions to Yersinia antigens were significantly more frequent than in the examined urban population (42% versus 20%, p<0.0001). The most frequent reactions were against Y. enterocolitica serotypes 05 and 08.  (+info)

Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH. (2/129)

The acquired immune responses are crucial to the survival of Yersinia-infected animals. Mice lacking T cells are sensitive to Yersinia infection, and a humoral response to Yersinia can be protective. Diverse mechanisms for Yersinia to impair and evade the host innate immune defense have been suggested, but the effects of Yersinia on lymphocytes are not known. Here, we demonstrate that after a transient exposure to Y. pseudotuberculosis, T and B cells are impaired in their ability to be activated through their antigen receptors. T cells are inhibited in their ability to produce cytokines, and B cells are unable to upregulate surface expression of the costimulatory molecule, B7.2, in response to antigenic stimulation. The block of lymphocyte activation results from the inhibition of early phosphorylation events of the antigen receptor signaling complex. Through the use of Y. pseudotuberculosis mutants, we show that the inhibitory effect in both T cells and B cells is dependent on the production of Yersinia outermembrane protein (Yop) H, a tyrosine phosphatase. Our results suggest a mechanism by which the pathogenic bacteria may modulate a wide range of T and B cell-mediated immune responses.  (+info)

Superantigen YPMa exacerbates the virulence of Yersinia pseudotuberculosis in mice. (3/129)

Yersinia pseudotuberculosis, a gram-negative bacterium responsible for enteric and systemic infection in humans, produces a superantigenic toxin designated YPMa (Y. pseudotuberculosis-derived mitogen). To assess the role of YPMa in the pathogenesis of Y. pseudotuberculosis, we constructed a superantigen-deficient mutant and compared its virulence in a mouse model of infection to the virulence of the wild-type strain. Determination of the survival rate after intravenous (i.v.) bacterial inoculation of OF1 mice clearly showed that inactivation of ypmA, encoding YPMa, reduced the virulence of Y. pseudotuberculosis. Mice infected i.v. with 10(4) and 10(5) wild-type bacteria died within 9 days, whereas mice infected with the ypmA mutant survived 12 and 3 days longer, respectively. This decreased virulence of the ypmA mutant strain was not due to an impaired colonization of the spleen, liver, or lungs. In contrast to i.v. challenge, bacterial inoculation by the intragastric (i.g.) route did not reveal any difference in virulence between wild-type Y. pseudotuberculosis and the ypmA mutant since the 50% lethal doses were identical for both strains. Moreover, inactivation of ypmA gene did not affect the bacterial growth of Y. pseudotuberculosis in Peyer's patches, mesenteric lymph nodes (MLNs), and spleen after oral infection. Histological studies of spleen, liver, lungs, heart, Peyer's patches, and MLNs after i.v. or i.g. challenge with the wild type or the ypmA mutant did not reveal any feature that can be specifically related to YPMa. Our data show that the superantigenic toxin YPMa contributes to the virulence of Y. pseudotuberculosis in systemic infection in mice.  (+info)

Infection of human enterocyte-like cells with rotavirus enhances invasiveness of Yersinia enterocolitica and Y. pseudotuberculosis. (4/129)

Mixed infection with rotavirus and either Yersinia enterocolitica or Y. pseudotuberculosis was analysed in Caco-2 cells, an enterocyte-like cell line highly susceptible to these pathogens. Results showed an increase of bacterial adhesion and internalisation in rotavirus-infected cells. Increased internalisation was also seen with Escherichia coli strain HB101 (pRI203), harbouring the inv gene from Y. pseudotuberculosis, which is involved in the invasion process of host cells. In contrast, the superinfection with bacteria of Caco-2 cells pre-infected with rotavirus resulted in decreased viral antigen synthesis. Transmission electron microscopy confirmed the dual infection of enterocytes. These data suggest that rotavirus infection enhances the early interaction between host cell surfaces and enteroinvasive Yersinia spp.  (+info)

Attributes of gammadelta intraepithelial lymphocytes as suggested by their transcriptional profile. (5/129)

gammadelta T lymphocytes in the intestinal intraepithelial layer (gammadelta IELs) are thought to contribute to immune competence, but their actual function remains poorly understood. Here we used DNA microarrays to study the gene expression profile of gammadelta IELs in a Yersinia infection system to better define their roles. To validate this approach, mesenteric lymph node CD8(+) alphabeta T cells were similarly analyzed. The transcription profiles show that, whereas lymph node CD8(+) alphabeta T cells must be activated to become cytotoxic effectors, gammadelta IELs are constitutively activated and appear to use different signaling cascades. Our data suggest that gammadelta IELs may respond efficiently to a broad range of pathological situations irrespective of their diverse T cell antigen receptor repertoire. gammadelta IELs may modulate local immune responses and participate in intestinal lipid metabolism, cholesterol homeostasis, and physiology. This study provides a strong basis for further investigations of the roles of these cells as well as mucosal immune defense in general.  (+info)

Geographical heterogeneity between Far Eastern and Western countries in prevalence of the virulence plasmid, the superantigen Yersinia pseudotuberculosis-derived mitogen, and the high-pathogenicity island among Yersinia pseudotuberculosis strains. (6/129)

Yersinia pseudotuberculosis produces novel superantigenic toxins designated YPMa (Y. pseudotuberculosis-derived mitogen), YPMb, and YPMc and has a pathogenicity island termed HPI (high-pathogenicity island) and R-HPI (the right-hand part of the HPI with truncation in its left-hand part) on the chromosome. Analysis of the distribution of these virulence factors allowed for differentiation of species Y. pseudotuberculosis into six subgroups, thus reflecting the geographical spread of two main clones: the YPMa(+) HPI(-) Far Eastern systemic pathogenic type belonging to serotypes O1b, -2a, -2b, -2c, -3, -4a, -4b, -5a, -5b, -6, -10, and UT (untypeable) and the YPMs(-) HPI(+) European gastroenteric pathogenic type belonging to serotypes O1a and -1b. The YPMa(+) HPI(+) pathogenic type belonging to serotypes O1b, -3, -5a, -5b, and UT and the YPMb(+) HPI(-) nonpathogenic type belonging to non-melibiose-fermenting serotypes O1b, -5a, -5b, -6, -7, -9, -10, -11, and -12 were prevalent in the Far East. The YPMc(+) R-HPI(+) European low-pathogenicity type belonging to non-melibiose-fermenting serotype O3 and the YPMs(-) HPI(-) pathogenic type belonging to 15 serotypes were found to be prevalent all over the world. This new information is useful for a better understanding of the evolution and spread of Y. pseudotuberculosis.  (+info)

DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae. (7/129)

Salmonella strains that lack or overproduce DNA adenine methylase (Dam) elicit a protective immune response to different Salmonella species. To generate vaccines against other bacterial pathogens, the dam genes of Yersinia pseudotuberculosis and Vibrio cholerae were disrupted but found to be essential for viability. Overproduction of Dam significantly attenuated the virulence of these two pathogens, leading to, in Yersinia, the ectopic secretion of virulence proteins (Yersinia outer proteins) and a fully protective immune response in vaccinated hosts. Dysregulation of Dam activity may provide a means for the development of vaccines against varied bacterial pathogens.  (+info)

Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes. (8/129)

Yersinia pestis, the causative agent of plague, and the enteropathogen Yersinia pseudotuberculosis have nearly identical nucleotide similarity yet cause markedly different diseases. To investigate this conundrum and to study Yersinia pathogenicity, we developed a high-density oligonucleotide array-based modification of signature-tagged mutagenesis (STM). Y. pseudotuberculosis YPIII mutants constructed with the tagged transposons were evaluated in the murine yersiniosis infection model. The DNA tags were amplified using biotinylated primers and hybridized to high-density oligonucleotide arrays containing DNA complementary to the tags. Comparison of the hybridization signals from input pools and output pools identified a mutant whose relative abundance was significantly reduced in the output pool. Sequence data from 31 transposon insertion regions was compared to the complete Y. pestis CO92 genome sequence. The 26 genes present in both species were found to be almost identical, but five Y. pseudotuberculosis genes identified through STM did not have counterparts in the Y. pestis genome and may contribute to the different tropisms in these closely related pathogens. Potential virulence genes identified include those involved in lipopolysaccharide biosynthesis, adhesion, phospholipase activity, iron assimilation, and gene regulation. The phospholipase A (PldA) mutant exhibited reduced phospholipase activity compared to the wild-type strain and in vivo attenuation of the mutant was confirmed. The combination of optimized double tag sequences and high-density array hybridization technology offers improved performance, efficiency, and reliability over classical STM and permits quantitative analysis of data.  (+info)

"Yersinia pseudotuberculosis" infections refer to illnesses caused by the bacterium Yersinia pseudotuberculosis. This gram-negative, rod-shaped bacterium is found in the environment, particularly in soil and water contaminated with animal feces. It can cause gastrointestinal infection in humans, leading to symptoms such as diarrhea, abdominal pain, fever, and vomiting. In severe cases, it can spread beyond the intestines and cause complications like skin lesions, joint inflammation, and spread to the bloodstream (septicemia). The incubation period for Yersinia pseudotuberculosis infections is typically 5-10 days. Diagnosis is usually made through culture of the bacterium from stool or other bodily fluids, and treatment typically involves antibiotics. Prevention measures include good hygiene practices, such as proper handwashing and avoiding consumption of contaminated food and water.

"Yersinia pseudotuberculosis" is a gram-negative, rod-shaped bacterium that is facultatively anaerobic, meaning it can grow in the presence or absence of oxygen. It is a causative agent of gastrointestinal illness in humans and animals, known as yersiniosis. The infection can cause symptoms such as diarrhea, abdominal pain, fever, and vomiting.

The bacterium is commonly found in the environment, particularly in soil and water, and can be transmitted to humans through contaminated food or water. It can also be spread through contact with infected animals, including birds and mammals.

Yersinia pseudotuberculosis is closely related to Yersinia pestis, the bacterium that causes plague, but it is generally less virulent in humans. However, in rare cases, it can cause severe illness, particularly in individuals with weakened immune systems.

Yersinia infections are caused by bacteria of the genus Yersinia, with Y. pestis (causing plague), Y. enterocolitica, and Y. pseudotuberculosis being the most common species associated with human illness. These bacteria can cause a range of symptoms depending on the site of infection.

Y. enterocolitica and Y. pseudotuberculosis primarily infect the gastrointestinal tract, causing yersiniosis. Symptoms may include diarrhea (often containing blood), abdominal pain, fever, vomiting, and inflammation of the lymph nodes in the abdomen. In severe cases, these bacteria can spread to other parts of the body, leading to more serious complications such as sepsis or meningitis.

Y. pestis is infamous for causing plague, which can manifest as bubonic, septicemic, or pneumonic forms. Bubonic plague results from the bite of an infected flea and causes swollen, painful lymph nodes (buboes) in the groin, armpits, or neck. Septicemic plague occurs when Y. pestis spreads through the bloodstream, causing fever, chills, extreme weakness, and potential organ failure. Pneumonic plague is a severe respiratory infection caused by inhaling infectious droplets from an infected person or animal; it can lead to rapidly progressing pneumonia, sepsis, and respiratory failure if left untreated.

Proper diagnosis of Yersinia infections typically involves laboratory testing of bodily fluids (e.g., blood, stool) or tissue samples to identify the bacteria through culture, PCR, or serological methods. Treatment usually consists of antibiotics such as doxycycline, fluoroquinolones, or aminoglycosides, depending on the severity and type of infection. Preventive measures include good hygiene practices, prompt treatment of infected individuals, and vector control to reduce the risk of transmission.

'Corynebacterium pseudotuberculosis' is a gram-positive, facultatively anaerobic, diphtheroid bacterium that is the causative agent of caseous lymphadenitis (CLA) in sheep and goats. It can also cause chronic, granulomatous infections in other animals, including horses, cattle, and humans. The bacteria are typically transmitted through contact with infected animals or contaminated environmental sources, such as soil or water. Infection can lead to the formation of abscesses in the lymph nodes, particularly in the head and neck region, as well as other organs.

In humans, 'Corynebacterium pseudotuberculosis' infection is rare but can cause a variety of clinical manifestations, including chronic lymphadenitis, osteomyelitis, pneumonia, and septicemia. The disease is often referred to as "pseudotuberculosis" or "pigeon breast" in humans, due to the characteristic swelling of the chest that can occur with infection.

Diagnosis of 'Corynebacterium pseudotuberculosis' infection typically involves the isolation and identification of the bacteria from clinical samples, such as pus or tissue biopsies. Treatment may involve surgical drainage of abscesses, along with antibiotic therapy. The choice of antibiotics depends on the severity and location of the infection, as well as the susceptibility of the bacterial strain.

Corynebacterium infections are caused by bacteria belonging to the genus Corynebacterium, which are gram-positive, rod-shaped organisms that commonly inhabit the skin and mucous membranes of humans and animals. While many species of Corynebacterium are harmless commensals, some can cause a range of infections, particularly in individuals with compromised immune systems or underlying medical conditions.

The most common Corynebacterium species that causes infection is C. diphtheriae, which is responsible for diphtheria, a potentially life-threatening respiratory illness characterized by the formation of a thick, grayish membrane in the throat and upper airways. Other Corynebacterium species, such as C. jeikeium, C. urealyticum, and C. striatum, can cause various types of healthcare-associated infections, including bacteremia, endocarditis, pneumonia, and skin and soft tissue infections.

Corynebacterium infections are typically treated with antibiotics, such as penicillin, erythromycin, or vancomycin, depending on the species of bacteria involved and the patient's medical history. In some cases, surgical intervention may be necessary to drain abscesses or remove infected tissue. Preventive measures, such as vaccination against C. diphtheriae and good hygiene practices, can help reduce the risk of Corynebacterium infections.

"Yersinia enterocolitica" is a gram-negative, facultatively anaerobic, rod-shaped bacterium that is capable of causing gastrointestinal infections in humans. It is commonly found in the environment, particularly in water and soil, as well as in animals such as pigs, cattle, and birds.

Infection with Yersinia enterocolitica can cause a range of symptoms, including diarrhea, abdominal pain, fever, and vomiting. The infection is typically transmitted through the consumption of contaminated food or water, although it can also be spread through person-to-person contact.

Yersinia enterocolitica infections are more common in young children and older adults, and they tend to occur more frequently during colder months of the year. The bacterium is able to survive at low temperatures, which may contribute to its prevalence in cooler climates.

Diagnosis of Yersinia enterocolitica infection typically involves the detection of the bacterium in stool samples or other clinical specimens. Treatment usually involves antibiotics and supportive care to manage symptoms. Prevention measures include good hygiene practices, such as washing hands thoroughly after using the bathroom and before handling food, as well as cooking meats thoroughly and avoiding consumption of raw or undercooked foods.

"Yersinia" is a genus of gram-negative bacteria that includes several species capable of causing human diseases. The most notable species are:

1. Yersinia pestis: This is the causative agent of plague, a severe and potentially fatal infectious disease. Plague can manifest in different forms, such as bubonic, septicemic, or pneumonic plague, depending on the route of infection. Historically, it has been associated with major pandemics like the Justinian Plague and the Black Death.

2. Yersinia pseudotuberculosis: This species is responsible for causing a gastrointestinal illness known as pseudoappendicitis or mesenteric adenitis, which can mimic appendicitis symptoms. Infection often results from consuming contaminated food or water.

3. Yersinia enterocolitica: Similar to Y. pseudotuberculosis, this species causes gastrointestinal infections, typically presenting as enterocolitis or terminal ileitis. Symptoms may include diarrhea, abdominal pain, and fever. In rare cases, it can lead to severe complications like sepsis or extraintestinal infections.

These bacteria are primarily transmitted through the fecal-oral route, either by consuming contaminated food or water or coming into contact with infected animals or their excrement. Proper hygiene practices and adequate cooking of food can help prevent Yersinia infections.

"Yersinia pestis" is a bacterial species that is the etiological agent (cause) of plague. Plague is a severe and often fatal infectious disease that can take various forms, including bubonic, septicemic, and pneumonic plagues. The bacteria are typically transmitted to humans through the bites of infected fleas, but they can also be spread by direct contact with infected animals or by breathing in droplets from an infected person's cough.

The bacterium is named after Alexandre Yersin, a Swiss-French bacteriologist who discovered it in 1894 during an epidemic of bubonic plague in Hong Kong. The disease has had a significant impact on human history, causing widespread pandemics such as the Justinian Plague in the 6th century and the Black Death in the 14th century, which resulted in millions of deaths across Europe and Asia.

Yersinia pestis is a gram-negative, non-motile, coccobacillus that can survive in various environments, including soil and water. It has several virulence factors that contribute to its ability to cause disease, such as the production of antiphagocytic capsules, the secretion of proteases, and the ability to resist phagocytosis by host immune cells.

Modern antibiotic therapy can effectively treat plague if diagnosed early, but without treatment, the disease can progress rapidly and lead to severe complications or death. Preventive measures include avoiding contact with infected animals, using insect repellent and protective clothing in areas where plague is endemic, and seeking prompt medical attention for any symptoms of infection.

Virulence, in the context of medicine and microbiology, refers to the degree or severity of damage or harm that a pathogen (like a bacterium, virus, fungus, or parasite) can cause to its host. It is often associated with the ability of the pathogen to invade and damage host tissues, evade or suppress the host's immune response, replicate within the host, and spread between hosts.

Virulence factors are the specific components or mechanisms that contribute to a pathogen's virulence, such as toxins, enzymes, adhesins, and capsules. These factors enable the pathogen to establish an infection, cause tissue damage, and facilitate its transmission between hosts. The overall virulence of a pathogen can be influenced by various factors, including host susceptibility, environmental conditions, and the specific strain or species of the pathogen.

Medical Definition:

Plague is a severe and potentially fatal infectious disease caused by the bacterium Yersinia pestis. It is primarily a disease of animals but can occasionally be transmitted to humans through flea bites, direct contact with infected animals, or inhalation of respiratory droplets from an infected person or animal.

There are three main clinical manifestations of plague: bubonic, septicemic, and pneumonic. Bubonic plague is characterized by painful, swollen lymph nodes (buboes) in the groin, armpits, or neck. Septicemic plague occurs when the bacteria spread throughout the bloodstream, causing severe sepsis and potentially leading to organ failure. Pneumonic plague is the most contagious form of the disease, involving infection of the lungs and transmission through respiratory droplets.

Plague is a zoonotic disease, meaning it primarily affects animals but can be transmitted to humans under certain conditions. The bacteria are typically found in small mammals, such as rodents, and their fleas. Plague is most commonly found in Africa, Asia, and South America, with the majority of human cases reported in Africa.

Early diagnosis and appropriate antibiotic treatment can significantly improve outcomes for plague patients. Public health measures, including surveillance, vector control, and vaccination, are essential for preventing and controlling outbreaks.

Bacterial adhesins are proteins or structures on the surface of bacterial cells that allow them to attach to other cells or surfaces. This ability to adhere to host tissues is an important first step in the process of bacterial infection and colonization. Adhesins can recognize and bind to specific receptors on host cells, such as proteins or sugars, enabling the bacteria to establish a close relationship with the host and evade immune responses.

There are several types of bacterial adhesins, including fimbriae, pili, and non-fimbrial adhesins. Fimbriae and pili are thin, hair-like structures that extend from the bacterial surface and can bind to a variety of host cell receptors. Non-fimbrial adhesins are proteins that are directly embedded in the bacterial cell wall and can also mediate attachment to host cells.

Bacterial adhesins play a crucial role in the pathogenesis of many bacterial infections, including urinary tract infections, respiratory tract infections, and gastrointestinal infections. Understanding the mechanisms of bacterial adhesion is important for developing new strategies to prevent and treat bacterial infections.

... pseudotuberculosis, and Y. pestis: the ignored species". Microbes and Infection. 2 (5): 497-513. doi:10.1016/s1286-4579(00) ... Yersinia aldovae is a species of bacteria that was originally described as Group X2 Yersinia enterocolitica. Its type strain is ... ISBN 0-683-00603-7. LSPN lpsn.dsmz.de "Yersinia aldovae" at the Encyclopedia of Life Type strain of Yersinia aldovae at BacDive ... Bercovier, H.; Steigerwalt, A. G.; Guiyoule, A.; Huntley-Carter, G.; Brenner, D. J. (1984). "Yersinia aldovae (Formerly ...
... pseudotuberculosis, and Y. pestis: the ignored species". Microbes and Infection. 2 (5): 497-513. doi:10.1016/s1286-4579(00) ... and Yersinia bercovieri sp. nov., formerly called Yersinia enterocolitica Biogroups 3A and 3B". International Journal of ... LSPN lpsn.dsmz.de "Yersinia mollaretii" at the Encyclopedia of Life Type strain of Yersinia mollaretii at BacDive - the ... Yersinia mollaretii is a Gram-negative species of bacteria. The species is named after Henri Mollaret, the former head of the ...
"Comparison of YopE and YopT activities in counteracting host signalling responses to Yersinia pseudotuberculosis infection". ... Similarly, YopE, YopP, and YopJ (in Yersinia enterocolitica, Yersinia pestis, and Yersinia pseudotuberculosis respectively) ... Yersinia inhibits phagocytosis through the concerted actions of several effector proteins, including YopE which acts as a ... NleC has been shown to cleave the NF-kB p65 subunit (RelA), blocking the production of IL-8 following infection. NleH1, but not ...
... lack of biofilm formation characterize Yersinia pseudotuberculosis infection of the Xenopsylla cheopis flea vector of Yersinia ... Among them was Yersinia-specific (also present in Y. pseudotuberculosis and Y. enterocolitica) Ysr141 (Yersinia small RNA 141 ... Its closest relatives are the gastrointestinal pathogen Yersinia pseudotuberculosis, and, more distantly, Yersinia ... "Yersinia pestis , the cause of plague, is a recently emerged clone of Yersinia pseudotuberculosis". Proceedings of the National ...
Yersinia pseudotuberculosis infection in children, resembling Izumi fever and Kawasaki syndrome. Pediatr Infect Dis 2: 123-126 ... The cause of this disease is Yersinia pseudotuberculosis serotype O1. 95% are subtype O1b.[citation needed] Yersinia ... the superantigen Yersinia pseudotuberculosis-derived mitogen, and the high-pathogenicity island among Yersinia ... Far East scarlet-like fever is an infectious disease caused by the gram negative bacillus Yersinia pseudotuberculosis. In Japan ...
However, in organisms like Vibrio cholerae and Yersinia pseudotuberculosis, the dam gene is essential for viability. A knockout ... Infection and Immunity. 69 (12): 7610-5. doi:10.1128/iai.69.12.7610-7615.2001. PMC 98854. PMID 11705940. Malone T, Blumenthal ... "DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio ...
... including O1 and non-O1 Vibrio parahaemolyticus Vibrio vulnificus Yersinia enterocolitica and Yersinia pseudotuberculosis Less ... its S. typhimurium infection is caused by consumption of eggs or poultry that are not adequately cooked or by other interactive ... Zearalenone Zearalenols Viral infections make up perhaps one third of cases of food poisoning in developed countries. In the US ... Toxins from bacterial infections are delayed because the bacteria need time to multiply. As a result, symptoms associated with ...
Yersinia pseudotuberculosis, and E. coli O157:H7 rely on a functioning Tat pathway for full virulence in infection models. In ...
... syndrome Yersinia pestis infection Yersiniosis Yersinia entercolitica infection Yersinia pseudotuberculosis infection Yim-Ebbin ... C D E F G H I J K L M N O P Q R S T U V W X Y Z See also Health Exercise Nutrition Y chromosome deletions Yaws Yeast infection ...
However, cases of zoo-sapronoses involving Listeria, Erysipelothrix, Yersinia pseudotuberculosis, Burkholderia pseudomallei, ... and capillaria infections were found in gorillas that maintained more frequent contact with humans than those that did not. ... Yersinia pseudotuberculosis, legionellosis, Pontiac fever, and nontuberculous mycobacterioses. Other sapronotic agents are ... The animal reservoir of the virus maintains a suitable virus level in the blood to allow the infection of a vector mosquito. A ...
Y. pseudotuberculosis infections can mimic appendicitis, especially in children and younger adults, and, in rare cases, the ... Yersinia pseudotuberculosis genome "Yersinia pseudotuberculosis". NCBI Taxonomy Browser. 632. Type strain of Yersinia ... Certain strains of Yersinia pseudotuberculosis express a superantigenic exotoxin, YPM, or the Y. pseudotuberculosis-derived ... "Impact of the Yersinia pseudotuberculosis -Derived Mitogen (YPM) on the Murine Immune System". The Genus Yersinia. Advances in ...
Experiments involving Yersinia pseudotuberculosis have been used to change the virulence phenotype of non-pathogenic bacteria ... Immunoglobulins are antibodies expressed and secreted by hosts in response to an infection. These immunoglobulins play a major ... YopT (Yersinia outer protein T) from Yersinia is an example of modification of the host. It modifies the proteolytic cleavage ... Examples for Yersinia pestis are an altered form of lipopolysaccharide, type three secretion system, and YopE and YopJ ...
Its closest relatives are Yersinia pseudotuberculosis and Yersinia enterocolitica, which are environmental species.[citation ... Therefore, for that infections that have caused the death of the host in the acute phase, the preferred sampling material is ... "Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis". Proceedings ... "Role of Yersinia murine toxin in survival of Yersinia pestis in the midgut of the flea vector". Science. 296 (5568): 733-735. ...
... yersinia infections MeSH C01.252.400.310.980.745 - plague MeSH C01.252.400.310.980.780 - yersinia pseudotuberculosis infections ... bacteroides infections MeSH C01.252.400.126 - bartonellaceae infections MeSH C01.252.400.126.100 - bartonella infections MeSH ... moraxellaceae infections MeSH C01.252.400.560.022 - acinetobacter infections MeSH C01.252.400.610 - mycoplasmatales infections ... salmonella infections, animal MeSH C01.252.400.310.821.873 - typhoid fever MeSH C01.252.400.310.850 - serratia infections MeSH ...
Yersinia pestis is in effect a strain of Yersinia pseudotuberculosis, but with a pathogenicity island that confers a ... Lan, R; Reeves, PR (2002). "Escherichia coli in disguise: molecular origins of Shigella". Microbes and Infection / Institut ... is a recently emerged clone of Yersinia pseudotuberculosis". Proceedings of the National Academy of Sciences of the United ... Achtman, M.; Zurth, K.; Morelli, G.; Torrea, G.; Guiyoule, A.; Carniel, E. (1999). "Yersinia pestis, the cause of plague, ...
Hansen P, Wenzel B, Brix T, Hegedüs L (2006). "Yersinia enterocolitica infection does not confer an increased risk of thyroid ... pseudotuberculosis, Y. rohdei, Y. ruckeri, Y. similis, and Y. wautersii. Among them, only Y. pestis, Y. pseudotuberculosis, and ... Yersinia enterocolitica genomes and related information at PATRIC, a Bioinformatics Resource Center funded by NIAID Yersinia ... Wikispecies has information related to Yersinia enterocolitica. Scholia has a topic profile for Yersinia enterocolitica. ...
Yersinia pseudotuberculosis, legionellosis, Pontiac fever, and nontuberculous mycobacterioses. Other sapronotic agents are ... Almost all fungal infections are sapronoses, but there are no known sapronotic viruses. Occupation often plays a role in ... 2018). "Distribution of Pathogens and Outbreak Fungi in the Fungal Kingdom". Emerging and Epizootic Fungal Infections in ...
Yersinia pestis, and Yersinia pseudotuberculosis. YadA stands for Yersinia adhesin protein A. This protein domain is an example ... The process of infection is complicated. The invasive bacterium must overcome many barriers in order to infect its host, ... The bacterium must enter the host's body and, in the case of Yersinia sp., invade the host intestinal mucosa. Then the Trimeric ... TAAs are just one of many methods bacteria use to infect their hosts, infection resulting in diseases such as pneumonia, sepsis ...
Dersch P, Isberg RR (March 1999). "A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated ... To reach the site of infection, phagocytes leave the bloodstream and enter the affected tissues. Signals from the infection ... If a bacterial infection spreads to the blood, TNF-α is released into vital organs, which can cause vasodilation and a decrease ... When an infection occurs, a chemical "SOS" signal is given off to attract phagocytes to the site. These chemical signals may ...
A/E lesion forming pathogens have high homology with each other and to invasin from Yersinia pseudotuberculosis and Yersinia ... "Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection". The Journal of Clinical Investigation. 92 ( ...
In the Falkow Lab, he worked on the conserved virulence plasmids in Yersinia enterocolitica, Yersinia pseudotuberculosis, and ... "Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis". Infection and ... Portnoy, D A; Falkow, S (1981-12-01). "Virulence-associated plasmids from Yersinia enterocolitica and Yersinia pestis". Journal ... Infection and Immunity. 79 (2): 688-694. doi:10.1128/IAI.00999-10. ISSN 0019-9567. PMC 3028833. PMID 21098106. "Eli Lilly and ...
In 2005, she was a summer intern at Stony Brook University in Gloria Viboud's lab where she studied Yersinia pseudotuberculosis ... Corbett, Kizzmekia Shanta (August 2014). Characterization of Human Antibody Responses to Dengue Virus Infections in a Sri ... "Pre-existing Neutralizing Antibody Responses Distinguish Clinically Inapparent and Apparent Dengue Virus Infections in a Sri ... "Preexisting Neutralizing Antibody Responses Distinguish Clinically Inapparent and Apparent Dengue Virus Infections in a Sri ...
... (Ybt) is a siderophore found in the pathogenic bacteria Yersinia pestis, Yersinia pseudotuberculosis, and ... Carniel, E. (2001). "The Yersinia high-pathogenicity island: An iron-uptake island". Microbes and Infection. 3 (7): 561-569. ... Perry, R. D.; Shah, J.; Bearden, S. W.; Thompson, J. M.; Fetherston, J. D. (2003). "Yersinia pestis TonB: Role in Iron, Heme, ... Sebbane, F.; Jarrett, C.; Gardner, D.; Long, D.; Hinnebusch, B. J. (2010). Ii, Roy Martin Roop (ed.). "Role of the Yersinia ...
... a plasmid only found in Yersinia pestis and not the related environmental agent Yersinia pseudotuberculosis, revealing that ... These types of infection probably both played a significant part in the Black Death, while a third strain was more rare. This ... "A Draft Genome of Yersinia pestis from Victims of the Black Death", Nature. Bos, Kirsten. "Eighteenth Century Yersinia pestis ... When the plague broke out in her household she was moved to a small village nearby, but she could not avoid infection, and died ...
2004). "Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis". Proc ... 2005). "Whole-genome analyses of speciation events in pathogenic Brucellae". Infection and Immunity. 73 (12): 8353-61. doi: ... 2006). "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging ... 2004). "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans". DNA Res. 11 (3): 179-97. doi ...
Y pseudotuberculosis primarily causes zoonotic infection in various hosts, including domestic and sylvatic animals and birds, ... but has been associated with food-borne infection in humans. ... common of the 3 main Yersinia species that cause infections in ... Pseudotuberculosis (Yersinia pseudotuberculosis Infection) * Sections Pseudotuberculosis (Yersinia pseudotuberculosis Infection ... Yersinia pseudotuberculosis Infection)) and Pseudotuberculosis (Yersinia pseudotuberculosis Infection) What to Read Next on ...
... describes two rare infections, Yersinia enterocolitica and Yersinia pseudotuberculosis. ... Yersinia enterocolitica and Yersinia pseudotuberculosis are bacterial infections that are uncommon, but can cause problems when ... In most children, the infection will go away on its own. In some cases, Yersinia infections need to be treated with antibiotics ... Healthy Children > Health Issues > Conditions > Abdominal > Rare Infections: Yersinia Enterocolitica and Yersinia ...
Tertti R, Granfors K, Lehtonen OP, Mertsola J, Makela AL, Valimaki I, An outbreak of Yersinia pseudotuberculosis infection. J ... Jalava K, Hallanvuo S, Nakari UM, Ruutu P, Kela E, Heinasmaki T, Multiple outbreaks of Yersinia pseudotuberculosis infections ... pseudotuberculosis infections are underrecognized in the United States. Diagnosis of Yersinia infections is difficult without ... Human and nonhuman infections caused by Yersinia pseudotuberculosis in Canada from 1962 to 1985. J Clin Microbiol. 1986;24:465- ...
Yersinia pseudotuberculosis a causal organism was detected in 16 patients (serotype 5A). The latent period of the infection was ... Three outbreaks of Yersinia pseudotuberculosis infection during 1982 to 1984 in Okayama Prefecture, Japan are described. In ... Epidemiological study of Yersinia enterocolitica and Yersinia pseudotuberculosis infections in Shimane Prefecture, Japan. ... Three outbreaks of yersinia pseudotuberculosis infection M Inoue 1 , H Nakashima, T Ishida, M Tsubokura ...
Haematological changes were followed in a field model of infection with Yersinia pseudotuberculosis using female weaver red ... Yersinia pseudotuberculosis. The haematology of acute bacterial infection in farmed red deer Cervus elaphus: Yersinia... Cross ... The haematology of acute bacterial infection in farmed red deer Cervus elaphus: Yersinia pseudotuberculosis Cross, J.; ... Haematological changes were followed in a field model of infection with Yersinia pseudotuberculosis using female weaver red ...
Tertti R, Granfors K, Lehtonen OP, Mertsola J, Makela AL, Valimaki I, An outbreak of Yersinia pseudotuberculosis infection. J ... Jalava K, Hallanvuo S, Nakari UM, Ruutu P, Kela E, Heinasmaki T, Multiple outbreaks of Yersinia pseudotuberculosis infections ... pseudotuberculosis infections are underrecognized in the United States. Diagnosis of Yersinia infections is difficult without ... Human and nonhuman infections caused by Yersinia pseudotuberculosis in Canada from 1962 to 1985. J Clin Microbiol. 1986;24:465- ...
Erythema nodosum, painful nodules on shins: Granulomatous fungal infections, histoplasmosis, coccidioidomycosis, Yersinia ... Yersinia enterocolitica/ Yersinia pseudotuberculosis: Mesenteric adenitis, pseudoappendicitis, with or without diarrhea ... Acute Parvovirus B19 infection can manifest with fever, arthralgias, rash, fatigue with fever being one of the most common ... Acute Epstein-Barr virus (EBV) infection is easily spread, and a small percentage of adults are not immune; fever for several ...
... and Yersinia pseudotuberculosis) our laboratory currently further explores. *Function of the microbiota in the control of ... Yasmine Belkaid obtained her Ph.D. in 1996 from the Pasteur Institute in France on innate responses to Leishmania infection. ... Role of the microbiota in immunity to infection. *Role of dietary metabolites in promoting immune regulation and immune ... Her dissertation work focused on understanding how host sensing of the gut microbiota influences viral infection. She is ...
... pseudotuberculosis, and Y. pestis: the ignored species". Microbes and Infection. 2 (5): 497-513. doi:10.1016/s1286-4579(00) ... Yersinia aldovae is a species of bacteria that was originally described as Group X2 Yersinia enterocolitica. Its type strain is ... ISBN 0-683-00603-7. LSPN lpsn.dsmz.de "Yersinia aldovae" at the Encyclopedia of Life Type strain of Yersinia aldovae at BacDive ... Bercovier, H.; Steigerwalt, A. G.; Guiyoule, A.; Huntley-Carter, G.; Brenner, D. J. (1984). "Yersinia aldovae (Formerly ...
Categories: Yersinia pseudotuberculosis Infections Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
The researchers examined the microbes of mice whod been infected with Yersinia pseudotuberculosis, a food-borne pathogen. ... References: Infection trains the host for microbiota-enhanced resistance to pathogens. Stacy A, Andrade-Oliveira V, McCulloch ... In fact, many protect you from harmful infections.. Bacteria live in colonies. This lets them work together to form defenses ... The team found that taurine given to mice as a supplement in drinking water also helped the microbiota to prevent infection. ...
Iron overload increases susceptibility of patients to Yersinia enterocolitica and Yersinia pseudotuberculosis infections. In ... Infections with Yersinia and Mucormycosis have been reported in association with deferoxamine mesylate use (see PRECAUTIONS). ... In such cases, deferoxamine mesylate treatment should be discontinued until the infection is resolved. ... some rare cases, treatment with deferoxamine mesylate has enhanced this susceptibility, resulting in generalized infections by ...
We study the closely related Gram-negative bacteria Yersinia pseudotuberculosis (YPTB) and Yersinia pestis (YP). These bacteria ... YP is transmitted by a flea vector and causes an acute lymphatic infection known as plague. We are investigating the ... Third, we are interested in uncovering mechanisms of host resistance to infection that rely on sensing the components of the ... provide a framework for the development of novel antimicrobial agents that can be used to treat or prevent bacterial infections ...
Yersinia infection can cause plague or yersiniosis, both of which are notifiable conditions. Plague may be naturally occurring ... Yersinia pestis causes plague and Yersinia enterocolitica causes yersiniosis. Infection with Yersinia pseudotuberculosis is ... Yersinia infection can cause plague or yersiniosis, both of which are notifiable conditions. Plague may be naturally occurring ... Infection is characterized by the sudden onset of systemic symptoms such as fever and painful swelling of lymph nodes (buboes) ...
How maternal infection experienced at distinct developmental stages shapes the offspring immune system remains poorly ... Here, we show that during pregnancy, maternally restricted infection can have permanent and tissue-specif … ... Yersinia pseudotuberculosis supports Th17 differentiation and limits de novo regulatory T cell induction by directly ... Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring Ai Ing Lim 1 , Taryn McFadden 1 , ...
... principally because few colonies of bats are available for experimental infections, a lack of reagents, methods and expertise ... Herpesviruses, Pasteurella spp., Salmonella spp., Yersinia pseudotuberculosis, Burkholderia spp., Cedecea davisae and ... Moreover, the data suggested that abortive infection did not provide durable immunity in bats and that repeated infections ... the fever response that occurs during infection is part of the immunological cascade initiated by infection or inflammation, in ...
Pore Formation and Signaling by the Yersinia pseudotuberculosis YopB protein" Infection and Immunity 73, 2433-2443. ... cell sterol composition upon internalization of Yersinia pseudotuberculosis and clustered beta-1 integrin" J. Biol. Chem. 293, ...
Global discovery of small RNAs in Yersinia pseudotuberculosis identifies Yersinia-specific small, noncoding RNAs required for ... which can cause a mild intestinal infection, and to about 12 other species of Yersinia. Why is one strain so much more ... However, Y. pestis is very closely related to the common gut and soil bacteria Yersinia pseudotuberculosis, ... Could a loss of important sRNAs in an ancient population of Y. pseudotuberculosis have led to Y. pestis and the plague? If so, ...
... bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in ... Yersinia enterocolitica and Y. pseudotuberculosis) and protozoal (Toxoplasma gondii) infections was similar for patients who ... Methods: Neurotropic infections that might predispose to ICI-induced neurological irAEs were analyzed in 61 melanoma patients ... Conclusion: Previous viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of ...
Plague and Other Yersinia Infections - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical ... Other Yersinia Infections Other Yersinia species, such as Yersinia enterocolitica and Yersinia pseudotuberculosis, infect ... than plague Plague and Other Yersinia Infections Plague is a severe infection caused by the gram-negative bacteria Yersinia ... Treatment of other Yersinia infections is focused on relieving the diarrhea. These infections usually resolve on their own. ...
Isolation of Yersinia spp. from cases of diarrhoea in Iraqi infants and children ... Intraperitoneal infection of rabbits was done by culturing Y. enterocolitica and Y. pseudotuberculosis in nutrient broth for 24 ... Role of Yersinia enterocolitica Yst toxin in experimental infection of young rabbits. Infection and immunity, 1992, 60(10):4269 ... Anti-Yersinia antibody production. The specificity of the raised anti-Yersinia antibodies was tested using Yersinia and other ...
Epidemiology and infection 2017 Jan 1-9 * Genomic insights into a sustained national outbreak of Yersinia pseudotuberculosis. ... Epidemiology and infection 2017 Feb (3) 503-514 * Social and Genetic Networks of HIV-1 Transmission in New York City. Wertheim ... Effect of a host-protein based assay on the differentiation of bacterial and viral infections in pre-school children. Esposito ... Multiple HPV infections in female sex workers in Western Kenya: implications for prophylactic vaccines within this sub ...
Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis. Proc Natl Acad ... Butler T. Yersinia infections: centennial of the discovery of the plague bacillus. Clin Infect Dis. 1994 Oct. 19(4):655-61; ... Three studies have shown that this bacterium emerged from the gut pathogen Yersinia pseudotuberculosis shortly after the first ... Humoral and cellular immune responses to Yersinia pestis infection in long-term recovered plague patients. Clin Vaccine Immunol ...
Yersinia. pseudotuberculosis.Journal: Acta Crystallographica Section D: Biological Crystallography Volume: 67 Issue: Pt 2, S- ... HANNOVERTWINCORE - Centre for Experimental and Clinical Infection ResearchHZI Study CentreCentre for Individualised Infection ... Helmholtz Centre for Infection Research. Inhoffenstraße 7. 38124 Braunschweig. +49 531 6181-0. Write E-Mail ... a structural view.Journal: Microbes and Infection Volume: 6, S-Page: 101- E-Page: 112 ...
YERSINIA 1977-86 & PSEUDOTUBERCULOSIS INFECTIONS, YERSINIA 1987-93; use YERSINIA PSEUDOTUBERCULOSIS INFECTIONS to search ... Infections with bacteria of the species YERSINIA PSEUDOTUBERCULOSIS.. Terms. Yersinia pseudotuberculosis Infections Preferred ... YERSINIA was see YERSINIA PSEUDOTUBERCULOSIS INFECTIONS 1987-93. Online Note. use YERSINIA PSEUDOTUBERCPLOSIS INFECTIONS to ... PSEUDOTUBERCULOSIS INFECTIONS, YERSINIA was see YERSINIA PSEUDOTUBERCULOSIS INFECTIONS 1987-93. Date Established. 1991/01/01. ...
YERSINIA 1977-86 & PSEUDOTUBERCULOSIS INFECTIONS, YERSINIA 1987-93; use YERSINIA PSEUDOTUBERCULOSIS INFECTIONS to search ... Infections with bacteria of the species YERSINIA PSEUDOTUBERCULOSIS.. Terms. Yersinia pseudotuberculosis Infections Preferred ... YERSINIA was see YERSINIA PSEUDOTUBERCULOSIS INFECTIONS 1987-93. Online Note. use YERSINIA PSEUDOTUBERCPLOSIS INFECTIONS to ... PSEUDOTUBERCULOSIS INFECTIONS, YERSINIA was see YERSINIA PSEUDOTUBERCULOSIS INFECTIONS 1987-93. Date Established. 1991/01/01. ...
Yersinia infection. Mucormycosis (in dialysis patients). Convulsions. Aggravation of hyperparathyroidism. Hepatic impairment. ... Yersinia enterocolitica or Y. pseudotuberculosis ). Discontinue if patient develops fever with pharyngitis, diffuse abdominal ... Yersinia infection. Mucormycosis (in dialysis patients). Convulsions. Aggravation of hyperparathyroidism. Hepatic impairment. ... Patients suffering from iron overload may be more susceptible to infections (e.g. Yersinia enterocolitica or Y. ...
Yersinia pestis infection. *Yersiniosis *Yersinia entercolitica infection. *Yersinia pseudotuberculosis infection. *Yim-Ebbin ...
  • We report that larvae of the wax moth ( Galleria mellonella ) are susceptible to infection with the human enteropathogen Yersinia pseudotuberculosis at 37 °C. Confocal microscopy demonstrated that in the initial stages of infection the bacteria were taken up into haemocytes. (microbiologyresearch.org)
  • Infections with bacteria of the species YERSINIA PSEUDOTUBERCULOSIS. (ucdenver.edu)
  • Yersinia aldovae is a species of bacteria that was originally described as Group X2 Yersinia enterocolitica. (wikipedia.org)
  • Yersinia is named in honor of Alexander Yersin, who successfully isolated the bacteria in 1894 during the pandemic that began in China in the 1860s. (medscape.com)
  • Pseudotuberculosis is an infection caused by the bacteria Yersinia pseudotuberculosis , which is transmitted through contact with food, bedding, and other material that is contaminated with feces of wild birds or rodents. (hamstercaretip.com)
  • Hamsters are exposed to the Yersinia pseudotuberculosis bacteria, which is responsible for pseudotuberculosis, when the feces of infected wild birds or rodents get into their food or drinking water. (hamstercaretip.com)
  • The bacteria is Yersinia Pseudotuberculosis - the "young" brother of Y. Pestis (causative agent of the plague). (scienceforums.net)
  • We recently found a family of adhesins, called MAMs, and many different bacteria use these sticky proteins to make contact with host tissues during an infection. (ukri.org)
  • MAMs aid the attachment of bacteria to host tissue, thus facilitating infection by a wide range of pathogens. (ukri.org)
  • We will test if MAMs from commensal and pathogenic bacteria differ in their lipid binding specificity and how these differences impact on the composition of mixed bacterial populations and the outcome of infection (Aim3). (ukri.org)
  • Recent research now suggests an adaptation to bacteria of the genus Yersinia . (blogspot.com)
  • To compensate for this underproduction of pyrin, there seems to have been selection for mutations that cause overproduction of pyrin, hence the high incidence of familial Mediterranean fever in populations that have coexisted with Yersinia bacteria (Loeven et al. (blogspot.com)
  • Yersinia is a genus of bacteria in the family Yersiniaceae. (arminlabs.com)
  • Yersiniosis is a disease caused by bacteria called Yersinia. (diseasesdic.com)
  • Yersinia are hardy bacteria that can survive in adverse conditions like refrigeration and environments low in oxygen. (diseasesdic.com)
  • Moreover, these infections the survival of Yersinia and other bacteria show a modest predilection for males, with in cold enrichment. (who.int)
  • The disease is caused by the plague bacillus, rod-shaped bacteria referred to as Yersinia pestis . (medscape.com)
  • Yersinia pseudotuberculosis is a cold-tolerant bacterial species in the family Enterobacteriaceae that most commonly causes foodborne illness, typically enterocolitis or mesenteric lymphadenitis (pseudoappendicitis) in children. (medscape.com)
  • We describe the Y. pseudotuberculosis infections reported through FoodNet surveillance sites and compare these infections with those caused by the more commonly identified Yersinia species, Y. enterocolitica . (cdc.gov)
  • The pathogenic Yersinia species possess a wide range of chromosomal and plasmid-derived virulence factors, which allow entry, adherence, invasion, dissemination, and release from the host. (medscape.com)
  • The phages exhibited relatively wide host ranges among Yersinia pseudotuberculosis and related species. (mdpi.com)
  • Prior to this study, three species of the enterobacterial genus Yersinia that cause invasive human diseases ( Yersinia pestis , Yersinia pseudotuberculosis , and Yersinia enterocolitica ) had been sequenced. (biomedcentral.com)
  • However, there were no genomic data on the Yersinia species with more limited virulence potential, frequently found in soil and water environments. (biomedcentral.com)
  • The most common species of Campylobacter associated with human illness are C. jejuni and C. coli , but other species can also cause human infections. (certest.es)
  • Yersinia species are further found in soil and waters. (arminlabs.com)
  • Although many species of Yersinia are found worldwide, most human illnesses are caused by Yersinia enterocolitica . (diseasesdic.com)
  • Other species of Yersinia affecting humans are Y. pseudotuberculosis , which causes an illness similar to Y. enterocolitica , and Y. pestis which causes plague. (diseasesdic.com)
  • Even adjusting for underreporting and difficulty in microbiological isolation, Y pseudotuberculosis appears to be a relatively rare pathogen in humans. (medscape.com)
  • Yersinia pseudotuberculosis , a gram-negative zoonotic bacterial pathogen, causes acute gastroenteritis and mesenteric lymphadenitis, which are often accompanied by fever and abdominal pain. (cdc.gov)
  • Three studies have shown that this bacterium emerged from the gut pathogen Yersinia pseudotuberculosis shortly after the first epidemic. (medscape.com)
  • Streptococcus suis type 2 (SS2), a major emerging/re-emerging zoonotic pathogen found in humans and pigs, can cause severe clinical infections, and pose public health issues. (qxmd.com)
  • Y enterocolitica and the related pathogen Y pseudotuberculosis produce at least 3 invasion proteins, Ail, YadA, and the aforementioned invasin, which could potentially promote adherence to and invasion of M cells. (diseasesdic.com)
  • First isolated in 1883 , Y pseudotuberculosis is a gram-negative bacterium that belongs to the genus Yersinia in the Enterobacteriaceae family. (medscape.com)
  • Rapid high-quality draft sequencing was used successfully to compare pathogenic and non-pathogenic members of the Yersinia genus. (biomedcentral.com)
  • Here we describe the deployment of new sequencing technology to extensively sample eight genomes from the Yersinia genus of the family Enterobacteriaceae. (biomedcentral.com)
  • As with other members of the genus Yersinia, Y enterocolitica is an invasive organism that appears to cause disease by tissue destruction. (diseasesdic.com)
  • Because of its 97% DNA homology with the agent that causes plague , Yersinia pestis, Y pseudotuberculosis is believed to have been the progenitor of the plague bacillus and is considered a model of bacterial evolution. (medscape.com)
  • [ 9 ] More optimistically, a specific strain of Y pseudotuberculosis, IP32953, has been modified into a potentially promising vaccine against bubonic and pneumonic plague. (medscape.com)
  • Yersinia infection can cause plague or yersiniosis, both of which are notifiable conditions. (bmj.com)
  • In humans, Yersinia pestis causes plague and Yersinia enterocolitica causes yersiniosis. (bmj.com)
  • We have also demonstrated that these receptors are recognizing Yersinia pestis , which is the plague bacterium. (livescience.com)
  • Plague is a natural infection of rodents and their ectoparasites and occurs in many parts of the world, including the western United States. (cdc.gov)
  • Routine bacteriologic precautions, including the use of a biological safety cabinet to isolate procedures that may produce aerosols, are sufficient to prevent accidental infection with plague among clinical laboratory workers. (cdc.gov)
  • Persons exposed to plague patients who have pneumonia or to Yersinia pestis *** aerosols in the laboratory should be given a 7- to 10-day course of antimicrobic therapy regardless of vaccination history. (cdc.gov)
  • In the eastern Mediterranean, people were likelier to survive bubonic plague if they had stronger inflammatory responses to infection in their lungs, gut, and other tissues. (blogspot.com)
  • Y. pestis causes bubonic plague, whereas Y. pseudotuberculosis and Y. enterocolitica cause gastroenteritis. (blogspot.com)
  • However, ground squirrels and prairie dogs have been known to be highly susceptible to plague, whereas others have been known to be either moderately susceptible or absolutely resistant to infection. (medscape.com)
  • It can harbor fleas infected with Yersinia pestis, the plague bacillus. (medscape.com)
  • Hjv (-∕-) and Hfe (C282Y∕C282Y) transgenic mice displayed enhanced colonization of deep tissues by Y. pseudotuberculosis following oral inoculation, recapitulating enhanced susceptibility of humans with HH to disseminated infection with enteropathogenic Yersinia. (escholarship.org)
  • Notably, CARD19 deficiency results in increased susceptibility tooral infection by Y. pseudotuberculosis further supporting the role of cell death in response to Yersinia infectionas a key host immune protective mechanism. (usda.gov)
  • Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion. (ox.ac.uk)
  • In this study, susceptibility to Yersinia enterocolitica and Yersinia pseudotuberculosis invasion was found to be increased upon overexpression of the deubiquitinating enzyme otubain 1 (OTUB1), a member of the ovarian tumour domain-containing protein family. (ox.ac.uk)
  • Infection with Yersinia pseudotuberculosis is uncommon and causes similar symptoms to yersiniosis. (bmj.com)
  • Yersiniosis is a rare disease in Muslim of Yersinia from the stool samples only to countries due to the scarcity of pork con- determine the highest possible number of sumption. (who.int)
  • There were seven outbreaks of Salmonella Typhimurium infection and five outbreaks of norovirus infection, two outbreaks of ciguatera poisoning and one outbreak each of campylobacteriosis and scombroid poisoning. (health.gov.au)
  • While seeming healthy and clean, Hedgehogs can transmit Salmonella infections in their droppings. (petnudge.com)
  • Infection with Salmonella can move from your intestines to the circulation and other body parts. (petnudge.com)
  • In Finland Yersinia is one of the main causes of bacterial diarrhea in addition of Salmonella and Campylobacter. (9pdf.co)
  • A review of human salmonellosis: III Magnitude of Salmonella infection in the United States. (docksci.com)
  • Update: Salmonella enteritidis infections and grade A shell eggs: United States, 1989. (docksci.com)
  • The emergence of grade A eggs as a major source of Salmonella enteritidis infections: new implications for the control of salmonellosis. (docksci.com)
  • VIASURE Salmonella , Campylobacter & Y. enterocolitica Real Time PCR Detection Kit is designed for specific detection and differentiation of Salmonella , Campylobacter and Yersinia enterocolitica in human stool samples from patients with signs and symptoms of gastrointestinal infection. (certest.es)
  • This test is intended for use as an aid in the diagnosis of the Salmonella , Campylobacter and/or Yersinia enterocolitica in combination with clinical and epidemiological risk factors. (certest.es)
  • DNA is extracted from stool specimens, multiplied using Real Time amplification and detected using specific primers and a fluorescent reporter dye probe for Salmonella , Campylobacter and/or Yersinia enterocolitica . (certest.es)
  • Target genes most frequently employed for rapid detection and identification of Salmonella , Campylobacter and Yersinia enterocolitica using Real Time PCR assays are the virulence invA gene (Salmonella invasion protein gene), 16S rRNA gene and ail (attachment-invasion locus) gene, respectively. (certest.es)
  • Y. pseudotuberculosis et Salmonella typhi ou S. paratyphi B, et entre Y. enterocolitica et Brucella a été détectée sérologiquement. (who.int)
  • We report a case of reactive polyarthritis in which serological evidence of Yersinia pseudotuberculosis infection was found in the absence of the other common precipitating organisms, such as Chlamydia spp, Klebsiella spp, Shigella spp, Campylobacter spp, or Yersinia enterocolitica. (bmj.com)
  • Enteropathogenic Escherichia coli infection (EPEC), Enterotoxigenic Escherichia coli infection (ETEC), Enteroinvasive Escherichia coli infection (EIEC), Enterohemorrhagic Escherichia coli infection (EHEC), Campylobacter enteritis, Enteritis due to Yersinia enterocolitica, and Enterocolitis due to Clostridium difficile. (codingahead.com)
  • Black R. E. , Levine M. M. , Clements M. L. , Hughes T. P. , Blaser M. J. Experimental Campylobacter jejuni infection in humans. (microbiologyresearch.org)
  • Infection with Campylobacter causes gastroenteritis characterised by fever, vomiting, headaches, and abdominal pain with watery or bloody diarrhea, for a median duration of 6 days. (certest.es)
  • Like Y. pestis , the enteropathogenic Yersiniae can escape macrophages and multiply outside host cells, but unlike their more virulent cogener, they only usually cause self-limiting inflammatory diseases. (biomedcentral.com)
  • It can be associated with postinfectious complications such as erythema nodosum and reactive arthritis , and strains of Y pseudotuberculosis found in Asia appear to produce a superantigen-associated toxic erythema illness suggestive of scarlet fever. (medscape.com)
  • A special form of Y pseudotuberculosis infection called Far East scarlet-like fever (FESLF) has been described in association with specific strains[7] of Y pseudotuberculosis in Russia and Japan that demonstrate mitogen A, which acts as a superantigen. (medscape.com)
  • First I want to thank Mikael Skurnik, who kindly offered me clinical Yersinia strains and gave valuable information about Yersinia, and my colleagues and instructor from Orion Diagnostica, who helped me during this study. (9pdf.co)
  • Y. pseudotuberculosis strains. (9pdf.co)
  • The iron overload disorder hereditary hemochromatosis (HH) predisposes humans to serious disseminated infection with pathogenic Yersinia as well as several other pathogens. (escholarship.org)
  • Some members of Yersinia are pathogenic in humans, such as Yersinia enterocolitica, Yersinia pseudotuberculosis and Yersinia pestis. (arminlabs.com)
  • The disease is caused by a coccobacillus-shaped, gram negative bacterium referred to as Yersinia pestis . (medscape.com)
  • In fact, because pseudotuberculosis is highly contagious and can spread to humans, your veterinarian may recommend euthanizing an infected hamster. (hamstercaretip.com)
  • Contagious infections can spread between hedgehogs and humans in a variety of ways. (petnudge.com)
  • Although zoonoses related to Dogs and Cats are just a small part of all the zoonoses, they are of increasing interest, as the number of companion animals and the number of humans with compromised immune system increases, and apart from the usual zoonoses some opportunistic till now infections have become more and more dangerous for the Public Health. (vin.com)
  • The most common source of Y. enterocolitica infection in humans is pork (raw or undercooked) and pigs are considered the main carrier. (diseasesdic.com)
  • These data suggest that Yersinia may rely on distinct virulence factors to cause disease in healthy vs. HH hosts. (escholarship.org)
  • Results: In 2021, 1354 patients were admitted with RSV infection. (bvsalud.org)
  • Many Y pseudotuberculosis outbreaks have occurred in zoos, animal-holding areas, and laboratory facilities. (medscape.com)
  • During the fourth quarter of 2003, OzFoodNet sites reported 174 outbreaks of gastrointestinal infections (Figure). (health.gov.au)
  • Outbreaks of gastroenteritis not transmitted by food have often not been reported to health agencies or the reports have been delayed, meaning that these figures significantly under represent the true burden of these infections. (health.gov.au)
  • The most common clinical Y pseudotuberculosis syndromes are self-limited enterocolitis and mesenteric lymphadenitis (pseudoappendicitis), but septicemia may occur in immunocompromised hosts, resulting in metastatic infection. (medscape.com)
  • Patients are often referred to the genitourinary clinic for screening for urethral infections after a clinical diagnosis of Reiter's syndrome or reactive arthritis. (bmj.com)
  • Consistent with previous reports using monocytes from HH vs. healthy donors, macrophages isolated from Hfe (C282Y∕C282Y) mice were defective in Yersinia uptake compared to wildtype macrophages, indicating that the anti-phagocytic property of the Yersinia T3SS plays a less important role in HH animals. (escholarship.org)
  • 111 females (44.4%), with mean age 13.9 colitica infection in children, including [standard deviation (SD) 15.2] months, enterocolitis, pseudoappendicitis syndrome, range 12 days to 12 years. (who.int)
  • To evaluate the utility of this model for screening Y. pseudotuberculosis mutants we constructed and tested a superoxide dismutase C ( sodC ) mutant. (microbiologyresearch.org)
  • Although Y. pseudotuberculosis infections are distributed worldwide, little is known about their incidence and epidemiology in the United States. (cdc.gov)
  • Y. pseudotuberculosis rarely is a reported cause of gastroenteritis and pseudoappendicitis in the United States, but recent epidemiological studies suggest that it may be an underdiagnosed cause of this illness. (medscape.com)
  • Physicians should maintain awareness of Y. pseudotuberculosis as a potential cause of gastroenteritis and pseudoappendicitis and know which diagnostic tests to order. (medscape.com)
  • Infections can be asymptomatic and cause self-limited gastroenteritis, but can also be associated with several infections and immunological complications. (9pdf.co)
  • Y. pseudotuberculosis and Y. enterocolitica (primarily biotype 1B) are enteropathogens that cause gastroenteritis following ingestion and translocation of the Peyer's patches. (biomedcentral.com)
  • Invasin, the principle invasion factor of Y enterocolitica and Y pseudotuberculosis , binds to ß 1 -chain integrin receptors with high affinity, promoting internalization. (diseasesdic.com)
  • On the basis of the source of specimen collection, infections were categorized as invasive (isolated from cerebrospinal fluid, blood, or another normally sterile site) or noninvasive (isolated from urine, stool, or other site). (cdc.gov)
  • Most of the Y. pseudotuberculosis infections reported in FoodNet sites appeared to be severe and invasive. (cdc.gov)
  • however, antibiotics may be required in invasive infection. (bmj.com)
  • Yersinia pseudotuberculosis (Yp)blocks NF-?B and MAPK signaling and interferes with inflammatory gene expression but also inducesapoptosis in innate immune cells. (usda.gov)
  • Microbial pathogens exploit the ubiquitin system to facilitate infection and manipulate the immune responses of the host. (ox.ac.uk)
  • Our research programme is based on our recent finding that early-life colonization by microbiota results in an epigenetic imprinting of unique functional properties within the gastrointestinal immune system and that neonatal infections can interfere with this process. (resist-cluster.de)
  • The rat fleas may then bite people and transmit infection. (msdmanuals.com)
  • Yersinia pseudotuberculosis Infections" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • Included are genes for a phage integrase, a tRNA Phe , several orthologues of genes of YAPI, a PAI of Yersinia pseudotuberculosis, and several putative virulence genes with HrpL-dependent promoter motifs. (elsevierpure.com)
  • From 1 July 2023, Prof Josef Penninger takes over the Scientific Management of the Helmholtz Centre for Infection Research (HZI). (helmholtz-hzi.de)
  • Overview of Pneumonia Pneumonia is an infection of the small air sacs of the lungs (alveoli) and the tissues around them. (msdmanuals.com)
  • Comparison of sputum microbiome of legionellosis-associated patients and other pneumonia patients: indications for polybacterial infections. (cdc.gov)
  • Y pseudotuberculosis appears to be cold tolerant, allowing transmission via contaminated cold-stored foods, handling of infected animal tissues, and cross-contamination during food preparation. (medscape.com)
  • Familial Mediterranean fever is due to mutations that increase the body's production of pyrin, a protein that assists inflammatory responses to infection of the lungs, gut, and other tissues. (blogspot.com)
  • Rodents are the natural reservoirs of Yersinia, less frequently, other mammals serve as hosts. (arminlabs.com)
  • Persons with Y. enterocolitica infection were significantly younger than those with Y. pseudotuberculosis infection (median age 6 years, p = 0.0002), and unlike Y. pseudotuberculosis infections, Y. enterocolitica infections were evenly distributed among male and female patients and among whites and blacks. (cdc.gov)
  • Compared with those with Y. enterocolitica infection, persons with Y. pseudotuberculosis infection were more likely to be hospitalized (p = 0.0003), have longer hospital stays (p = 0.0118), die (p = 0. (cdc.gov)
  • To investigate how host iron overload influences Y. pseudotuberculosis virulence and the requirement for the Ysc type III secretion system (T3SS), we utilized two distinct murine models of HH: hemojuvelin knockout mice that mimic severe, early-onset HH as well as mice with the Hfe (C282Y∕C282Y) mutation carried by 10% of people of Northern European descent, associated with adult-onset HH. (escholarship.org)
  • The generally accepted pathway for the evolution of these more severe disease-causing Yersiniae is memorably encapsulated by the recipe, 'add DNA, stir, reduce' [ 17 ]. (biomedcentral.com)
  • Chronic implant-related bone infections are a severe complication in orthopaedic surgery. (qxmd.com)
  • The median age of persons with Y. pseudotuberculosis infection was 47 years (range 16-86 years), and 67% were male ( Table ). (cdc.gov)
  • Infection may occur either through blood (in the case of Y. pestis) or in an alimentary fashion, occasionally via consumption of food products (especially vegetables, milk-derived products, and meat) contaminated with infected urine or feces. (arminlabs.com)
  • Below we cover seven types of Bacterial Gastrointestinal Infections. (codingahead.com)
  • Serious Infections: Cases of mucormycosis and Yersinia infections, some fatal, have occurred. (nih.gov)
  • In addition to extreme weight loss with persistent diarrhea and swollen lymph nodes in the neck or shoulder, the pseudotuberculosis infection may eventually spread to hamster's the bloodstream, which is fatal. (hamstercaretip.com)
  • You're a professional senior scientist with a PhD in some flavor of chemistry or biology and you stopped off on your way to the doctor to ask on an online forum whether Yersinia Pseudotuberculosis could be fatal if swallowed? (scienceforums.net)
  • Typhoid fever ( S. Typhi and S. Paratyphi infections) reportable. (cdc.gov)
  • Infections and parasitic diseases. (docksci.com)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
  • Y pseudotuberculosis is associated with postinfectious complications such as erythema nodosum, reactive arthritis, iritis , and glomerulonephritis. (medscape.com)
  • Yersinia pseudotuberculosis infection as a cause of reactive arthritis as seen in a genitourinary clinic: case report. (bmj.com)
  • Isolation of Yersinia spp. (who.int)
  • A direct lymphatic link between the Peyer patches and mesenteric lymph nodes may result in bacterial dissemination to these sites, resulting in mesenteric lymphadenitis or systemic infection. (diseasesdic.com)
  • Recently, the areas of the most intensive epidemic and epizootic infection have been some countries in Africa, Asia, and South America. (cdc.gov)
  • Conversely, OTUB1 knockdown interfered with Yersinia invasion in HEK293T cells as well as in primary monocytes. (ox.ac.uk)
  • Developed singleplex and duplex Yersinia assays were also shortly optimized by adjusting one parameter at the time. (9pdf.co)
  • Y pseudotuberculosis infection occurs worldwide but appears to be most common as sporadic disease in northern Europe and Asia, primarily as a zoonotic infection of rabbits and other mammals and birds. (medscape.com)
  • Galleria mellonella as a model host to study infection by the Francisella tularensis live vaccine strain. (microbiologyresearch.org)
  • How CARD19-induced cell death is coupled to inflammatoryresponses and host defense against bacterial infection is not known. (usda.gov)
  • Bacterial toxins damage the host at the site of bacterial infection or distant from the site. (springer.com)
  • We have also observed that, if many MAMs are brought together on the host cell surface, this changes signaling processes within the host so that it becomes more prone to infection. (ukri.org)
  • 2016). The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome. (blogspot.com)
  • This effect is modulated by post-translational modifications of OTUB1, suggesting a new entry point for manipulating Yersinia interactions with the host. (ox.ac.uk)
  • Examples frequently encountered in developed countries include colon cancer, Crohn's disease, and, less commonly, infection due to Yersinia enterocolitica and Y. pseudotuberculosis (see related topic reviews). (medilib.ir)