Ailanthus
Plant growth regulatory effect and insecticidal activity of the extracts of the Tree of Heaven (Ailanthus altissima L.). (1/8)
BACKGROUND: There is an urgent need to explore and utilize naturally occurring products for combating harmful agricultural and public health pests. Secondary metabolites in the leaves of the Tree of Heaven, Ailanthus altissima L. have been reported to be herbicidal and insecticidal. The mode of action, however, of the active compounds in A. altissima are not understood. In this paper, we report the chemical characteristics of the herbicidal and insecticidal components in this tree, and will discuss the effect of light on the bioactivity of the active components. RESULTS: Extracts from the fresh leaves of A. altissima showed a strong plant germination/growth inhibitory effect in laboratory bioassays against alfalfa (Medicago sativa). The effect was dose-dependent. The growth inhibitory components were in the methylene chloride soluble fraction of the extract. The effect was greater in the light than in the dark. Other fractions had plant growth enhancing effect at lower concentrations. The extract was slightly insecticidal against yellow fever mosquito larvae (Aedes aegypti). CONCLUSIONS: The extract or its semi-purified fractions of A. altissima were strong plant growth inhibitors, therefore good candidates as potential environmentally safe and effective agricultural pest management agents. The finding that light affects the activity will be useful in the application of such natural products. (+info)Three new quassinoids, ailantinol E, F, and G, from Ailanthus altissima. (2/8)
Three new quassinoids, ailantinol E (1), ailantinol F (2), and ailantinol G (3), and related compounds were isolated from Ailanthus altissima grown in Taiwan. Their structures were elucidated from spectral evidence. Each new quassinoid was evaluated for its antitumor promoting effects against Epstein-Barr virus early antigen activation introduced by 12-O-tetradecanoylphorbol-13-acetate in Raji cells. The new quassinoids were found to show potent activity without showing any cytotoxicity. The screening for inhibitors against nitric oxide donor action was also conducted using the new quassinoids and some standard samples. (+info)1-Methoxy-canthin-6-one induces c-Jun NH2-terminal kinase-dependent apoptosis and synergizes with tumor necrosis factor-related apoptosis-inducing ligand activity in human neoplastic cells of hematopoietic or endodermal origin. (3/8)
We investigated the effects of 1-methoxy-canthin-6-one, isolated from the medicinal plant Ailanthus altissima Swingle, on apoptosis in human leukemia (Jurkat), thyroid carcinoma (ARO and NPA), and hepatocellular carcinoma (HuH7) cell lines. Cultures incubated with the compound showed >50% of sub-G1 (hypodiploid) elements in flow cytometry analysis; the apoptosis-inducing activity was evident at <10 micromol/L and half-maximal at about 40 micromol/L 1-methoxy-canthin-6-one. The appearance of hypodiploid elements was preceded by mitochondrial membrane depolarization, mitochondrial release of cytochrome c, and Smac/DIABLO and procaspase-3 cleavage. We subsequently investigated the effect of 1-methoxy-canthin-6-one in combination with human recombinant tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in the four cell lines. Suboptimal concentrations (10 micromol/L 1-methoxy-canthin-6-one and 0.25 ng/mL TRAIL, respectively) of the two agents, unable to elicit apoptosis when used alone, induced mitochondrial depolarization, activation of caspase-3, and 45% to 85% of sub-G1 elements when added together to the cells. The synergism seemed to rely partly on the enhanced expression of TRAIL receptor 1 (TRAIL-R1; DR4), analyzed by immunofluorescence, by 1-methoxy-canthin-6-one. Cell incubation with 1-methoxy-canthin-6-one resulted in activating c-Jun NH2-terminal kinase (JNK), as revealed by Western blotting; induction of apoptosis and TRAIL-R1 up-regulation by 1-methoxy-canthin-6-one were >80% prevented by the addition of the JNK inhibitor (JNKI) SP600125JNKI, indicating that both effects were almost completely mediated by JNK activity. On the other hand, synergism with TRAIL was reduced by about 50%, suggesting that besides up-regulating TRAIL-R1, 1-methoxy-canthin-6-one could influence other factor(s) that participated in TRAIL-induced apoptosis. These findings indicate that 1-methoxy-canthin-6-one can represent a candidate for in vivo studies of monotherapies or combined antineoplastic therapies. (+info)Anti-inflammatory activity of Ailanthus altissima in ovalbumin-induced lung inflammation. (4/8)
As part of an ongoing investigation to find bioactive medicinal herbs exerting anti-inflammation activity, the effect of an ethanol extract from the parts of Ailanthus altissima (Simaroubaceae) was evaluated in both in vitro and in in vivo system. The ethanol extract of A. altissima (EAa) inhibited generation of the cyclooxygenase-2 (COX-2) dependent phases of prostaglandin D2 in bone marrow-derived mast cells (BMMC) in a concentration-dependent manner with an IC50 value of 214.6 microg/ml. However, this compound did not inhibit COX-2 protein expression up to a concentration of 400 microg/ml in the BMMC, indicating that EAa directly inhibits COX-2 activity. In addition, EAa inhibited leukotriene C4 production with an IC50 value of 25.7 microg/ml. Furthermore, this compound inhibited degranulation reaction in a dose dependent manner, with an IC50 value of 27.3 microg/ml. Ovalbumin (OVA)-sensitized mice were orally pretreated with EAa before aerosol challenges. EAa reduced the eosinophil infiltration into the airway and the eotaxin, IL-4, and IL-13 mRNA expression levels. These results suggest that the anti-inflammation activity of A. altissima in OVA-induced lung inflammation may occur in part via the down regulation of T(H)2 cytokines and eotaxin transcripts as well as the inhibition of inflammatory mediators. (+info)Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition. (5/8)
(+info)A novel triterpenoid isolated from the root bark of Ailanthus excelsa Roxb (Tree of Heaven), AECHL-1 as a potential anti-cancer agent. (6/8)
(+info)Antiasthmatic activity of luteolin-7-O-glucoside from Ailanthus altissima through the downregulation of T helper 2 cytokine expression and inhibition of prostaglandin E2 production in an ovalbumin-induced asthma model. (7/8)
Previously, we reported that an ethanol extract of Ailanthus altissima has antiinflammatory activity in an ovalbumin (OVA)-sensitized murine asthmatic model. To determine the biological compounds from this plant, luteolin-7-O-glucoside (L7G) was isolated and its antiasthmatic activity was evaluated in an in vivo murine asthmatic model. L7G (10 to 100 mg/kg, per os (p.o.)) reduced the amount of eosinophil infiltration in bronchoalveolar lavage (BAL) fluid in a dose-dependent manner. In comparison, dexamethasone (5 mg/kg, p.o.), which was used as a positive control, also strongly inhibited the number of infiltrating eosinophils. L7G inhibited both the prostaglandin E(2) (PGE(2)) and serum immunoglobulin E level in BAL fluid in a dose-dependent manner. In addition, L7G inhibited the transcript profiles of interleukin (IL)-4, IL-5, and IL-13 mRNA expression levels in the murine asthma model, as determined using reverse transcription-polymerase chain reaction (RT-PCR). These results suggest that the antiasthmatic activity of L7G in OVA-induced lung inflammation may occur in part via the downregulation of T helper 2 cytokine transcripts as well as the inhibition of PGE(2) production. (+info)Human-mediated dispersal of seeds by the airflow of vehicles. (8/8)
(+info)'Ailanthus' is a genus name that refers to a type of tree commonly known as the "tree of heaven." The scientific name for this tree is *Ailanthus altissima*. It is native to China and has been introduced in various parts of the world, including North America. While it is often used as an ornamental tree, it can be invasive in some areas due to its prolific seed production and ability to grow in a variety of conditions.
It's worth noting that 'Ailanthus' is not a medical term and does not have a direct connection to human health or medicine. However, like many plants, parts of the tree of heaven have been used in traditional medicine in some cultures. For example, the bark and roots have been used in Chinese medicine for various purposes, such as treating skin conditions, digestive issues, and menstrual discomfort. However, it's important to note that these uses have not been widely studied or proven in modern clinical trials, so their effectiveness and safety are not established.
If you have any specific medical concerns or questions, I would recommend consulting with a qualified healthcare professional for accurate information and guidance.
Quassinoids are a group of naturally occurring compounds that are found in various plants, including the bark of Quassia amara, a tree native to South America. Quassins, one type of quassinoid, have been studied for their potential medicinal properties, particularly as antimalarial and anticancer agents. They are known to interact with cell membranes and can affect the growth and multiplication of certain types of cells. However, more research is needed to fully understand their mechanisms of action and potential therapeutic uses. It's important to note that quassins can also be toxic in high concentrations, so further studies are necessary to determine safe and effective dosages for medical use.
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Altissima15
- Species include: Ailanthus altissima (Mill. (wikipedia.org)
- But when people introduced Asian tree-of-heaven ( Ailanthus altissima ) to North America - and those trees spread invasively - this moth soon had a suitable host plant occurring far north of where it had been able to live before. (mo.gov)
- collected from Ailanthus altissima are described and illustrated from Hungary. (mtak.hu)
- 网页臭椿(Ailanthus altissima(Mill. (kyoweb.eu)
- Chunpi, Cortex Ailanthi, is the dry root bark or stem bark of Ailanthus altissima (Mill. (kyoweb.eu)
- 网页2021-7-15 Ethnopharmacological relevance: The dried bark of Ailanthus altissima (Mill. (kyoweb.eu)
- 网页摘要:本文对椿皮Ailanthus altissima (Mill. (kyoweb.eu)
- 网页2007-7-27 Ailanthus altissima (tree of heaven), Simaroubaceae, is an early successional tree, native to China and North Vietnam, which has become invasive in Europe and on all other continents except Antarctica. (kyoweb.eu)
- 网页Being so invasive and mass spread all over the country Ailanthus altissima could be regarded as a rich and cheap resource to utilize and a potential background for a possible approach to restrict its populations. (kyoweb.eu)
- Ailanthus (Ailanthus altissima) also known as tree of heaven occurs in several parts of Caumsett State Park along woodland edges and forest openings. (caumsettprojects.org)
- Home » Species » Plantae » Magnoliophyta » Rosopsida » Sapindales » Simaroubaceae » Ailanthus » Ailanthus altissima - (P. Mill. (myspecies.info)
- Ailanthus altissima is extremely fast growing tree and commonly known as tree of heaven. (wordinn.com)
- Verticillium albo-atrum causes unprecedented wilt and mortality of the invasive tree-of-heaven (Ailanthus altissima) within forests of south-central Pennsylvania. (psu.edu)
- Those are seedlings of tree of heaven (Ailanthus altissima), according to Clair Ryan, coordinator of the Midwest Invasive Plant Network ( MIPN.org ), based at The Morton Arboretum in Lisle. (chicagotribune.com)
- 4. Antiproliferative effects of tree-of-heaven (Ailanthus altissima Swingle). (nih.gov)
Simaroubaceae1
- Ailanthus excelsa Roxb is a tree, indigenous to central and southern India, belongs to family Simaroubaceae is widely used in Ayurveda and evidence based phytotherapy. (faithangelgroup.in)
Desf1
- Spotted lanternfly Ailanthus Desf. (wikipedia.org)
Moth2
Species3
- Ailanthus , also known as " Tree of Heaven", is a unique species that has its origins in Eastern Asia. (shopsweetestbeginnings.com)
- NonAilanthus tree species growing adjacent to dead and dying Ailanthus trees in the field were asymptomatic. (psu.edu)
- Although the species was deliberately imported from China in the 18th century as a street tree, hardly any of the ailanthus trees that have sprouted since then across Europe and the United States were planted on purpose. (chicagotribune.com)
Excelsa2
- Ailanthus excelsa Roxb. (wikipedia.org)
- Our product range includes a wide range of royal ailanthus excelsa tree seed. (faithangelgroup.in)
Genus1
- any of several deciduous Asian trees of the genus Ailanthus. (wordinn.com)
Invasive3
- But elsewhere in North America, the caterpillars eat the introduced, invasive tree-of-heaven or ailanthus tree, which is in the same family. (mo.gov)
- ABOVE AND TO THE RIGHT: The group removed a 2″ strip of bark from the trunks of 75 invasive male and female Ailanthus trees. (caumsettprojects.org)
- Pending further studies, V. albo-atrum should be considered as a potential biocontrol agent for invasive Ailanthus. (psu.edu)
Webworm1
- Ailanthus webworm moths cannot survive cold winters, so when it freezes, northern populations are wiped out. (mo.gov)
Vilmoriniana1
- Ailanthus vilmoriniana KR 265 had reached 19 m at the Valley Gardens, Windsor Great Park, UK, by July 2021. (treesandshrubsonline.org)
Bark1
- Able to grow under adverse conditions Ailanthus also produces a poisonous "ailanthene" in bark and leaves that helps limit competition posing a threat to Caumsett's forest communities. (caumsettprojects.org)
Seedlings1
- Stem, inoculation of potted Ailanthus seedlings in the greenhouse and canopy Ailanthus trees in the field with V. albo-atrum resulted in 100% mortality. (psu.edu)
Tree3
- As a fast-growing tree and a prolific seeder, Ailanthus can take over relatively sunny sites, replacing native plants. (caumsettprojects.org)
- This female Ailanthus tree located in an open sunny area within the test site continued to live during the 2015 summer despite being girdled twice. (caumsettprojects.org)
- According to the 2020 Chicago Region Tree Census conducted by the Arboretum, 5% of all trees in the city are ailanthus. (chicagotribune.com)
Trees5
- They live communally in webs in ailanthus trees. (mo.gov)
- Downed native trees resulting from Super Storm Sandy produced open areas within Caumsett's forest thereby creating potential sites for Ailanthus to establish itself. (caumsettprojects.org)
- Above Ailanthus trees were girdled for a second time during the summer of 2014. (caumsettprojects.org)
- Dead Ailanthus trees along woodland edge in test site. (caumsettprojects.org)
- Among pinnate-leaved trees of similar character, the ailanthus is easily recognised by the glandular teeth near the base of the leaflets. (treesandshrubsonline.org)
Stem1
- The only way to really put an end to a mature ailanthus or a grove of suckers is by stem injection with a systemic herbicide that will kill off the roots," Ryan said. (chicagotribune.com)
Leaves1
- A very Rare Sterling Silver Fish Fork by Tiffany & Co. "Ailanthus Pattern" Unusual and exotic leaves on the front and back make up the design and shape of Handle detail of Tiffany & Co circa 1900. (sarasotaantiquebuyers.com)
Similar1
- Similar to Ailanthus Ailanth . (abchomeopathy.com)
Usage1
- Below are the main rubriks (i.e strongest indications or symptoms) of Ailanthus in traditional homeopathic usage , not approved by the FDA. (abchomeopathy.com)
Project1
- On March 22, 2014 eight volunteers met at Caumsett State Park Preserve to participate in the Park's pilot project to eradicate Ailanthus. (caumsettprojects.org)
China1
- China Ailanthus integrifolia Lam. (wikipedia.org)