A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.
INFLAMMATION of any ARTERIES.
A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)
The type species of the genus ARTERIVIRUS and the etiologic agent of an important equine respiratory disease causing abortion, pneumonia, or other infections.
Arteries arising from the external carotid or the maxillary artery and distributing to the temporal region.
A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.
Infections caused by viruses of the genus ARTERIVIRUS.
A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.
A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*52 allele family.
Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.
Diseases of domestic and wild horses of the species Equus caballus.
Measurement of rate of settling of erythrocytes in anticoagulated blood.
Inflammation of the wall of the AORTA.
A genus of the family ARTERIVIRIDAE, in the order NIDOVIRALES. The type species is ARTERITIS VIRUS, EQUINE.
A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.
A clinically significant reduction in blood supply to the BRAIN STEM and CEREBELLUM (i.e., VERTEBROBASILAR INSUFFICIENCY) resulting from reversal of blood flow through the VERTEBRAL ARTERY from occlusion or stenosis of the proximal subclavian or brachiocephalic artery. Common symptoms include VERTIGO; SYNCOPE; and INTERMITTENT CLAUDICATION of the involved upper extremity. Subclavian steal may also occur in asymptomatic individuals. (From J Cardiovasc Surg 1994;35(1):11-4; Acta Neurol Scand 1994;90(3):174-8)
The continuation of the subclavian artery; it distributes over the upper limb, axilla, chest and shoulder.
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)
Radiography of blood vessels after injection of a contrast medium.
An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.
Infection of horses with parasitic nematodes of the superfamily STRONGYLOIDEA. Characteristics include the development of hemorrhagic nodules on the abdominal peritoneum.
The first and largest artery branching from the aortic arch. It distributes blood to the right side of the head and neck and to the right arm.
Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.
Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61)
Adrenal cortex hormones are steroid hormones produced by the outer portion of the adrenal gland, consisting of glucocorticoids, mineralocorticoids, and androgens, which play crucial roles in various physiological processes such as metabolism regulation, stress response, electrolyte balance, and sexual development and function.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Substances that reduce or suppress INFLAMMATION.
A rod-shaped bacterium isolated from milk and cheese, dairy products and dairy environments, sour dough, cow dung, silage, and human mouth, human intestinal contents and stools, and the human vagina.
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.
Acute or chronic inflammation of the arachnoid membrane of the meninges most often involving the spinal cord or base of the brain. This term generally refers to a persistent inflammatory process characterized by thickening of the ARACHNOID membrane and dural adhesions. Associated conditions include prior surgery, infections, trauma, SUBARACHNOID HEMORRHAGE, and chemical irritation. Clinical features vary with the site of inflammation, but include cranial neuropathies, radiculopathies, and myelopathies. (From Joynt, Clinical Neurology, 1997, Ch48, p25)
Inflammation of ARTERIES in the CENTRAL NERVOUS SYSTEM that occurs in patients with ACQUIRED IMMUNODEFICIENCY SYNDROME or AIDS-RELATED OPPORTUNISTIC INFECTIONS.
A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
A PREDNISOLONE derivative with similar anti-inflammatory action.
Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.
Sudden ISCHEMIA in the RETINA due to blocked blood flow through the CENTRAL RETINAL ARTERY or its branches leading to sudden complete or partial loss of vision, respectively, in the eye.
The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.
An abnormal balloon- or sac-like dilatation in the wall of AORTA.
A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)
A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
A family of RNA viruses, mainly arboviruses, consisting of two genera: ALPHAVIRUS (group A arboviruses), and RUBIVIRUS. Virions are spherical, 60-70 nm in diameter, with a lipoprotein envelope tightly applied to the icosahedral nucleocapsid.
The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
Nutrient blood vessels which supply the walls of large arteries or veins.
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Transient complete or partial monocular blindness due to retinal ischemia. This may be caused by emboli from the CAROTID ARTERY (usually in association with CAROTID STENOSIS) and other locations that enter the central RETINAL ARTERY. (From Adams et al., Principles of Neurology, 6th ed, p245)
The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
Vaccines used in conjunction with diagnostic tests to differentiate vaccinated animals from carrier animals. Marker vaccines can be either a subunit or a gene-deleted vaccine.
The main trunk of the systemic arteries.
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The vessels carrying blood away from the heart.
The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).

Adventitial delivery minimizes the proinflammatory effects of adenoviral vectors. (1/236)

PURPOSE: Adenovirus-mediated arterial gene transfer is a promising tool in the study of vascular biology and the development of vascular gene therapy. However, intraluminal delivery of adenoviral vectors causes vascular inflammation and neointimal formation. Whether these complications could be avoided and gene transfer efficiency maintained by means of delivering adenoviral vectors via the adventitia was studied. METHODS: Replication-defective adenoviral vectors encoding a beta-galactosidase (beta-gal) gene (AdRSVnLacZ) or without a recombinant gene (AdNull) were infused into the lumen or the adventitia of rabbit carotid arteries. Two days after infusion of either AdRSVnLacZ (n = 8 adventitial, n = 8 luminal) or AdNull (n = 4 luminal), recombinant gene expression was quantitated by histochemistry (performed on tissue sections) and with a beta-gal activity assay (performed on vessel extracts). Inflammation caused by adenovirus infusion was assessed 14 days after infusion of either AdNull (n = 6) or vehicle (n = 6) into the carotid adventitia. Inflammation was assessed by means of examination of histologic sections for the presence of neointimal formation and infiltrating T cells and for the expression of markers of vascular cell activation (ICAM-1 and VCAM-1). To measure the systemic immune response to adventitial infusion of adenovirus, plasma samples (n = 3) were drawn 14 days after infusion of AdNull and assayed for neutralizing antibodies. RESULTS: Two days after luminal infusion of AdRSVnLacZ, approximately 30% of luminal endothelial cells expressed beta-gal. Similarly, 2 days after infusion of AdRSVnLacZ to the adventitia, approximately 30% of adventitial cells expressed beta-gal. beta-gal expression was present in the carotid adventitia, the internal jugular vein adventitia, and the vagus nerve perineurium. Elevated beta-gal activity (50- to 80-fold more than background; P <.05) was detected in extracts made from all AdRSVnLacZ-transduced arteries. The amount of recombinant protein expression per vessel did not differ significantly between vessels transduced via the adventitia (17.1 mU/mg total protein [range, 8.1 to 71.5]) and those transduced via a luminal approach (10.0 mU/mg total protein [range, 3.9 to 42.6]). Notably, adventitial delivery of AdNull did not cause neointimal formation. In addition, vascular inflammation in arteries transduced via the adventitia (ie, T-cell infiltrates and ICAM-1 expression) was confined to the adventitia, sparing both the intima and media. Antiadenoviral neutralizing antibodies were present in all rabbits after adventitial delivery of AdNull. CONCLUSION: Infusion of adenoviral vectors into the carotid artery adventitia achieves recombinant gene expression at a level equivalent to that achieved by means of intraluminal vector infusion. Because adventitial gene transfer can be performed by means of direct application during open surgical procedures, this technically simple procedure may be more clinically applicable than intraluminal delivery. Moreover, despite the generation of a systemic immune response, adventitial infusion had no detectable pathologic effects on the vascular intima or media. For these reasons, adventitial gene delivery may be a particularly useful experimental and clinical tool.  (+info)

Expression of interleukin-10 in advanced human atherosclerotic plaques: relation to inducible nitric oxide synthase expression and cell death. (2/236)

Inflammation is a major feature of human atherosclerosis and is central to development and progression of the disease. A variety of proinflammatory cytokines are expressed in the atherosclerotic plaque and may modulate extracellular matrix remodeling, cell proliferation, and cell death. Little is known, however, about the expression and potential role of anti-inflammatory cytokines in human atherosclerosis. Interleukin-10 (IL-10) is a major anti-inflammatory cytokine whose expression and potential effects in advanced human atherosclerotic plaques have not been evaluated. We studied 21 advanced human atherosclerotic plaques. IL-10 expression was analyzed by use of reverse transcription-polymerase chain reaction and immunohistochemical techniques. Inducible nitric oxide synthase expression was assessed by using immunohistochemistry, and cell death was determined by use of the TUNEL method. Reverse transcription-polymerase chain reaction identified IL-10 mRNA in 12 of 17 atherosclerotic plaques. Immunohistochemical staining of serial sections and double staining identified immunoreactive IL-10 mainly in macrophages, as well as in smooth muscle cells. Consistent with its anti-inflammatory properties, high levels of IL-10 expression were associated with significant decrease in inducible nitric oxide synthase expression (P<0.0001) and cell death (P<0. 0001). Hence, IL-10, a potent anti-inflammatory cytokine, is expressed in a substantial number of advanced human atherosclerotic plaques and might contribute to the modulation of the local inflammatory response and protect from excessive cell death in the plaque.  (+info)

Cerebral arterial lesions resulting from inflammatory emboli. (3/236)

In order to study the effects of septic embolism on the brain, silicone rubber emboli of various types were injected into the carotid arteries of 35 dogs. Pathologic and angiographic studies were performed to assess the resultant arterial and parenchymal lesions. Pure silicone rubber emboli (14 dogs) produced occasional intra-arterial thrombosis but no arteritis. Sterile and bacterially contaminated emboli containing a lead-chromate pigment (similar to those used in previous studies of septic embolism) (11 dogs) and pure silicone rubber emboli with transversely oriented canals (10 dogs), after brief placement in a bacterial suspension, were associated with intense inflammatory arteritis. This was accompanied by focal meningitis, subarachnoid hemorrhage, thrombosis, and cerebritis of the underlying cortex. The findings resembled those found in mycotic aneurysm. Aneurysmal dilatation was observed in one postmortem angiogram. In previous models of mycotic aneurysm, the inflammation attributed to bacterial contamination was probably due to the lead-chromate pigment used.  (+info)

Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries. (4/236)

Plasma concentration of markers of inflammation are increased in patients with atherosclerosis. However, it is unclear whether the pattern and magnitude of this increase vary with the site and extent of disease. In 147 patients undergoing semiquantitative coronary angiography, we measured the acute-phase reactants C-reactive protein (CRP) or serum amyloid A (SAA); the proinflammatory cytokine interleukin 6 (IL-6); the active and total fractions of the anti-inflammatory cytokine transforming growth factor-beta (TGF-beta); the macrophage activation marker neopterin; and the infection marker procalcitonin. Compared with 62 patients without either coronary artery disease (CAD) or peripheral artery disease (PAD), 57 patients with CAD but no PAD showed greater median CRP (0. 4 versus 0.2 mg/dL, P=0.004) and IL-6 (3.8 versus 1.6 pg/mL, P=0. 007) levels and a lower level of active-TGF-beta (57 versus 100 ng/mL, P=0.038). Moreover, CRP, IL-6, and neopterin levels showed a positive and the active TGF-beta level a negative correlation with the extent of coronary atherosclerosis. Compared with these 57 patients with CAD alone, 15 patients with PAD and CAD had higher median levels of SAA (17 versus 7 mg/mL, P=0.008), IL-6 (12 versus 4 pg/mL, P=0.002), neopterin (14 versus 11 mg/dL, P=0.006), and total TGF-beta (11834 versus 6417 ng/L, P=0.001). However, these strong univariate associations of markers of inflammation and atherosclerosis were lost in multivariate analysis once age, sex, and high density lipoprotein cholesterol or fibrinogen were taken into account. Increased plasma levels of CRP, SAA, IL-6, TGF-beta, neopterin, and procalcitonin constitute an inflammatory signature of advanced atherosclerosis and are correlated with the extent of disease but do not provide discriminatory diagnostic power over and above established risk factors.  (+info)

Clinical utility of the erythrocyte sedimentation rate. (5/236)

The erythrocyte sedimentation rate (ESR) determination is a commonly performed laboratory test with a time-honored role. However, the usefulness of this test has decreased as new methods of evaluating disease have been developed. The test remains helpful in the specific diagnosis of a few conditions, including temporal arteritis, polymyalgia rheumatica and, possibly, rheumatoid arthritis. It is useful in monitoring these conditions and may predict relapse in patients with Hodgkin's disease. Use of the ESR as a screening test to identify patients who have serious disease is not supported by the literature. Some studies suggest that the test may be useful as a "sickness index" in the elderly or as a screening tool for a few specific infections in certain settings. An extreme elevation of the ESR is strongly associated with serious underlying disease, most often infection, collagen vascular disease or metastatic malignancy. When an increased rate is encountered with no obvious clinical explanation, the physician should repeat the test after an appropriate interval rather than pursue an exhaustive search for occult disease.  (+info)

Unusual complications in an inflammatory abdominal aortic aneurysm. (6/236)

An unusual case of an inflammatory abdominal aortic aneurysm (IAAA) associated with coronary aneurysms and pathological fracture of the adjacent lumbar vertebrae. The associated coronary lesions in cases of IAAA are usually occlusions. In the present case, it was concluded that a possible cause of the coronary aneurysm was coronary arteritis and the etiology of the pathological fracture of the lumbar vertebrae was occlusion of the lumbar penetrating arteries due to vasculitis resulting in aseptic necrosis. Inflammatory AAA can be associated with aneurysms in addition to occlusive disease in systemic arteries. The preoperative evaluation of systemic arterial lesions and the function of systemic organs is essential.  (+info)

Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene. (7/236)

Branch points and flexures in the high pressure arterial system have long been recognized as sites of unusually high turbulence and consequent stress in humans are foci for atherosclerotic lesions. We show that mice that are homozygous for a null mutation in the gene encoding an endogenous antiinflammatory cytokine, interleukin 1 receptor antagonist (IL-1ra), develop lethal arterial inflammation involving branch points and flexures of the aorta and its primary and secondary branches. We observe massive transmural infiltration of neutrophils, macrophages, and CD4(+) T cells. Animals appear to die from vessel wall collapse, stenosis, and organ infarction or from hemorrhage from ruptured aneurysms. Heterozygotes do not die from arteritis within a year of birth but do develop small lesions, which suggests that a reduced level of IL-1ra is insufficient to fully control inflammation in arteries. Our results demonstrate a surprisingly specific role for IL-1ra in the control of spontaneous inflammation in constitutively stressed artery walls, suggesting that expression of IL-1 is likely to have a significant role in signaling artery wall damage.  (+info)

Neointima formation in a restenosis model is suppressed in midkine-deficient mice. (8/236)

Neointima formation is a common feature of atherosclerosis and restenosis after balloon angioplasty. To find a new target to suppress neointima formation, we investigated the possible role of midkine (MK), a heparin-binding growth factor with neurotrophic and chemotactic activities, in neointima formation. MK expression increased during neointima formation caused by intraluminal balloon injury of the rat carotid artery. Neointima formation in a restenosis model was strongly suppressed in MK-deficient mice. Continuous administration of MK protein to MK-deficient mice restored neointima formation. Leukocyte recruitment to the vascular walls after injury was markedly decreased in MK-deficient mice. Soluble MK as well as that bound to the substratum induced migration of macrophages in vitro. These results indicate that MK plays a critical role in neointima formation at least in part owing to its ability to mediate leukocyte recruitment.  (+info)

Takayasu arteritis is a rare inflammatory disease that affects the large blood vessels in the body, most commonly the aorta and its main branches. It's also known as pulseless disease or aortic arch syndrome. The condition primarily affects young to middle-aged women, although it can occur in anyone at any age.

The inflammation caused by Takayasu arteritis can lead to narrowing, thickening, and weakening of the affected blood vessels' walls, which can result in reduced blood flow to various organs and tissues. This can cause a variety of symptoms depending on the severity and location of the vessel involvement.

Common symptoms include:

* Weak or absent pulses in the arms and/or legs
* High blood pressure (hypertension)
* Dizziness, lightheadedness, or fainting spells due to reduced blood flow to the brain
* Headaches
* Visual disturbances
* Fatigue
* Weight loss
* Night sweats
* Fever

Diagnosis of Takayasu arteritis typically involves a combination of medical history, physical examination, laboratory tests, and imaging studies. Treatment usually includes corticosteroids or other immunosuppressive medications to control inflammation and maintain remission. Regular follow-up with a healthcare provider is essential to monitor disease activity and adjust treatment as necessary.

Arteritis is a medical condition characterized by inflammation of the arteries. It is also known as vasculitis of the arteries. The inflammation can cause the walls of the arteries to thicken and narrow, reducing blood flow to affected organs or tissues. There are several types of arteritis, including:

1. Giant cell arteritis (GCA): Also known as temporal arteritis, it is a condition that mainly affects the large and medium-sized arteries in the head and neck. The inflammation can cause headaches, jaw pain, scalp tenderness, and vision problems.
2. Takayasu's arteritis: This type of arteritis affects the aorta and its major branches, mainly affecting young women. Symptoms include fever, weight loss, fatigue, and decreased pulse in the arms or legs.
3. Polyarteritis nodosa (PAN): PAN is a rare systemic vasculitis that can affect medium-sized arteries throughout the body. It can cause a wide range of symptoms, including fever, rash, abdominal pain, and muscle weakness.
4. Kawasaki disease: This is a type of arteritis that mainly affects children under the age of 5. It causes inflammation in the blood vessels throughout the body, leading to fever, rash, swollen lymph nodes, and red eyes.

The exact cause of arteritis is not fully understood, but it is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks its own tissues. Treatment for arteritis typically involves medications to reduce inflammation and suppress the immune system.

Giant Cell Arteritis (GCA), also known as Temporal Arteritis, is a chronic inflammatory disease affecting large and medium-sized arteries, most commonly the temporal artery. It primarily occurs in people over 50 years old. The condition is characterized by the infiltration of the artery walls with immune cells, leading to inflammation, swelling, and damage. This can restrict blood flow, causing various symptoms.

The key feature of GCA is the presence of multinucleated giant cells, which are large collections of fused immune cells, in the affected artery walls. These cells are a hallmark of this condition when viewed under a microscope.

Common symptoms include new onset of severe headaches, scalp tenderness, jaw pain while chewing (called jaw claudication), vision problems, and systemic symptoms such as fever, fatigue, and weight loss. If left untreated, GCA can lead to serious complications like blindness or stroke. Treatment typically involves high-dose corticosteroids to reduce inflammation and prevent further damage.

I'm sorry for any confusion, but there seems to be a mistake in your question. "Arteritis Virus, Equine" is not a recognized medical term or virus in humans or animals. There is a condition called "Equine Viral Arteritis (EVA)," which is a viral disease that affects horses and other equine species. However, it does not affect humans.

Equine Viral Arteritis (EVA) is caused by the Equine Arteritis Virus (EAV). This virus primarily affects the respiratory system and can cause symptoms such as fever, lethargy, loss of appetite, and a runny nose in infected horses. In some cases, it may also lead to inflammation of the lining of blood vessels (vasculitis), which can result in abortion in pregnant mares or infertility in stallions.

It's essential to maintain proper biosecurity measures when dealing with horses, especially those that have been exposed to EVA, to prevent its spread and protect the health of other equine populations.

Temporal arteries are the paired set of arteries that run along the temples on either side of the head. They are branches of the external carotid artery and play a crucial role in supplying oxygenated blood to the scalp and surrounding muscles. One of the most common conditions associated with temporal arteries is Temporal Arteritis (also known as Giant Cell Arteritis), which is an inflammation of these arteries that can lead to serious complications like vision loss if not promptly diagnosed and treated.

Polymyalgia Rheumatica (PMR) is a geriatric rheumatic disease characterized by widespread musculoskeletal pain and stiffness, particularly affecting the neck, shoulders, hips, and thighs. It is often accompanied by symptoms such as fatigue, weakness, loss of appetite, and low-grade fever. The onset of PMR can be sudden or gradual, and it tends to affect individuals over 50 years of age, more commonly women than men.

The exact cause of Polymyalgia Rheumatica remains unknown; however, it is believed to involve an autoimmune response leading to inflammation in the affected areas. Diagnosis typically involves a combination of clinical evaluation, laboratory tests (such as elevated erythrocyte sedimentation rate or C-reactive protein), and sometimes imaging studies. Treatment usually includes corticosteroids to reduce inflammation and manage symptoms, along with monitoring for potential side effects from long-term steroid use. In many cases, PMR can be successfully managed with appropriate treatment, allowing individuals to return to their normal activities.

Arterivirus infections are viral diseases caused by members of the Arteriviridae family, which includes several species that can infect a variety of animals. The most well-known arterivirus is the equine arteritis virus (EAV), which causes equine arteritis in horses. Other examples include the porcine reproductive and respiratory syndrome virus (PRRSV) in pigs, and simian hemorrhagic fever virus (SHFV) in non-human primates.

Arterivirus infections typically cause respiratory or reproductive symptoms, depending on the specific virus and host species. For example, EAV can cause respiratory disease, abortion, and infertility in horses, while PRRSV primarily affects the reproductive system of pigs, causing abortions, stillbirths, and weak piglets.

Transmission of arteriviruses typically occurs through direct contact with infected animals or their bodily fluids, such as respiratory droplets or semen. Some arteriviruses can also be transmitted vertically, from mother to offspring, during pregnancy or birth.

There are currently no specific treatments for arterivirus infections, and prevention efforts focus on biosecurity measures, such as quarantine and vaccination of susceptible animals.

Polyarteritis nodosa (PAN) is a rare, systemic necrotizing vasculitis that affects medium-sized and small muscular arteries. It is characterized by inflammation and damage to the walls of the arteries, leading to the formation of microaneurysms (small bulges in the artery wall) and subsequent narrowing or complete occlusion of the affected vessels. This can result in tissue ischemia (reduced blood flow) and infarction (tissue death), causing a wide range of clinical manifestations that vary depending on the organs involved.

The exact cause of PAN remains unclear, but it is believed to involve an autoimmune response triggered by various factors such as infections or exposure to certain drugs. The diagnosis of PAN typically requires a combination of clinical findings, laboratory tests, and imaging studies, often supported by histopathological examination of affected tissues. Treatment usually involves the use of immunosuppressive medications to control inflammation and prevent further damage to the arteries and organs.

HLA-B52 is a specific antigen of the human leukocyte antigen (HLA) system, which is located on chromosome 6 and plays an important role in the immune system. The HLA system helps the body to recognize and distinguish its own cells from foreign substances such as viruses and bacteria.

HLA-B52 is a type of HLA-B antigen, which is a group of proteins found on the surface of cells that help the immune system identify and destroy infected or damaged cells. The HLA-B52 antigen is most commonly found in individuals of Asian descent, particularly those from Japan and Korea.

It's important to note that the presence or absence of the HLA-B52 antigen does not necessarily indicate the presence or absence of a specific disease. However, certain genetic associations have been reported between HLA-B52 and some diseases such as Behçet's disease, which is a chronic inflammatory disorder that causes symptoms such as mouth sores, genital sores, eye inflammation, and skin lesions.

Aortic arch syndromes are a group of conditions that affect the aortic arch, which is the curved portion of the aorta that arises from the left ventricle of the heart and gives rise to the major branches of the arterial system. These syndromes are typically caused by congenital abnormalities or degenerative changes in the aorta and can result in various complications, such as obstruction of blood flow, aneurysm formation, and dissection.

There are several types of aortic arch syndromes, including:

1. Coarctation of the Aorta: This is a narrowing of the aorta at the point where it leaves the heart, just distal to the origin of the left subclavian artery. It can cause hypertension in the upper extremities and reduced blood flow to the lower extremities.
2. Aortic Arch Aneurysm: This is a localized dilation or bulging of the aorta in the region of the aortic arch. It can lead to dissection, rupture, or embolism.
3. Aortic Arch Dissection: This is a separation of the layers of the aortic wall, which can result from hypertension, trauma, or genetic disorders such as Marfan syndrome. It can cause severe chest pain, shortness of breath, and shock.
4. Kommerell's Diverticulum: This is an outpouching or bulge in the aorta at the origin of the ligamentum arteriosum, which is a remnant of the ductus arteriosus. It can cause compression of the airways or esophagus and increase the risk of dissection or rupture.
5. Abernethy Malformation: This is a rare congenital anomaly in which there is an abnormal connection between the portal vein and systemic venous circulation, leading to the bypass of the liver. It can cause various complications such as hepatic encephalopathy, pulmonary hypertension, and liver tumors.

The diagnosis and management of aortic arch syndromes require a multidisciplinary approach involving cardiologists, radiologists, surgeons, and other specialists. Treatment options may include medications, endovascular procedures, or surgical interventions depending on the severity and location of the lesion.

I understand you are asking for a medical definition of "Horse Diseases." However, it's important to note that there isn't a specific medical field dedicated to horse diseases as we typically categorize medical fields by human diseases and conditions. Veterinary medicine is the field responsible for studying, diagnosing, and treating diseases in animals, including horses.

Here's a general definition of 'Horse Diseases':

Horse diseases are health issues or medical conditions that affect equine species, particularly horses. These diseases can be caused by various factors such as bacterial, viral, fungal, or parasitic infections; genetic predispositions; environmental factors; and metabolic disorders. Examples of horse diseases include Strangles (Streptococcus equi), Equine Influenza, Equine Herpesvirus, West Nile Virus, Rabies, Potomac Horse Fever, Lyme Disease, and internal or external parasites like worms and ticks. Additionally, horses can suffer from musculoskeletal disorders such as arthritis, laminitis, and various injuries. Regular veterinary care, preventative measures, and proper management are crucial for maintaining horse health and preventing diseases.

Blood sedimentation, also known as erythrocyte sedimentation rate (ESR), is a medical test that measures the rate at which red blood cells settle at the bottom of a tube of unclotted blood over a specific period of time. The test is used to detect and monitor inflammation in the body.

During an acute inflammatory response, certain proteins in the blood, such as fibrinogen, increase in concentration. These proteins cause red blood cells to stick together and form rouleaux (stacks of disc-shaped cells). As a result, the red blood cells settle more quickly, leading to a higher ESR.

The ESR test is a non-specific test, meaning that it does not identify the specific cause of inflammation. However, it can be used as an indicator of underlying conditions such as infections, autoimmune diseases, and cancer. The test is also used to monitor the effectiveness of treatment for these conditions.

The ESR test is usually performed by drawing a sample of blood into a special tube and allowing it to sit undisturbed for one hour. The distance that the red blood cells have settled is then measured and recorded as the ESR. Normal values for ESR vary depending on age and gender, with higher values indicating greater inflammation.

Aortitis is a medical condition characterized by inflammation of the aorta, which is the largest artery in the body that carries oxygenated blood from the heart to the rest of the body. The inflammation can cause damage to the aortic wall, leading to weakening, bulging (aneurysm), or tearing (dissection) of the aorta. Aortitis can be caused by various conditions, including infections, autoimmune diseases, and certain medications. It is essential to diagnose and treat aortitis promptly to prevent serious complications.

Arterivirus is a type of enveloped, single-stranded, positive-sense RNA virus that belongs to the family Arteriviridae. These viruses are named after their initial discovery in arteries and have since been found to infect a wide range of mammals, including pigs, horses, cats, and primates.

Arteriviruses can cause various diseases, such as porcine reproductive and respiratory syndrome (PRRS) in pigs, equine arteritis virus (EAV) in horses, and simian hemorrhagic fever virus (SHFV) in non-human primates. In humans, Arterivirus infection is rare, but some cases of human infection with porcine reproductive and respiratory syndrome virus have been reported.

Arteriviruses are characterized by their unique viral structure, including a distinctive "coronavirus-like" appearance due to the presence of club-shaped projections on their surface called peplomers. However, they differ from coronaviruses in several ways, such as genome organization and replication strategy.

Overall, Arterivirus is an important group of viruses that can cause significant economic losses in the livestock industry and pose a potential threat to human health.

Prednisolone is a synthetic glucocorticoid drug, which is a class of steroid hormones. It is commonly used in the treatment of various inflammatory and autoimmune conditions due to its potent anti-inflammatory and immunosuppressive effects. Prednisolone works by binding to specific receptors in cells, leading to changes in gene expression that reduce the production of substances involved in inflammation, such as cytokines and prostaglandins.

Prednisolone is available in various forms, including tablets, syrups, and injectable solutions. It can be used to treat a wide range of medical conditions, including asthma, rheumatoid arthritis, inflammatory bowel disease, allergies, skin conditions, and certain types of cancer.

Like other steroid medications, prednisolone can have significant side effects if used in high doses or for long periods of time. These may include weight gain, mood changes, increased risk of infections, osteoporosis, diabetes, and adrenal suppression. As a result, the use of prednisolone should be closely monitored by a healthcare professional to ensure that its benefits outweigh its risks.

The subclavian artery is a major blood vessel that supplies the upper limb and important structures in the neck and head. It arises from the brachiocephalic trunk (in the case of the right subclavian artery) or directly from the aortic arch (in the case of the left subclavian artery).

The subclavian artery has several branches, including:

1. The vertebral artery, which supplies blood to the brainstem and cerebellum.
2. The internal thoracic artery (also known as the mammary artery), which supplies blood to the chest wall, breast, and anterior mediastinum.
3. The thyrocervical trunk, which gives rise to several branches that supply the neck, including the inferior thyroid artery, the suprascapular artery, and the transverse cervical artery.
4. The costocervical trunk, which supplies blood to the neck and upper back, including the posterior chest wall and the lower neck muscles.

The subclavian artery is a critical vessel in maintaining adequate blood flow to the upper limb, and any blockage or damage to this vessel can lead to significant morbidity, including arm pain, numbness, weakness, or even loss of function.

I'm sorry for any confusion, but "horses" is not a medical term. It is the common name given to the species *Equus ferus caballus*, which are large domesticated mammals used for transportation, work, and recreation. If you have any questions about horses or a related topic that you would like a medical perspective on, please let me know and I'd be happy to help!

Subclavian Steal Syndrome is a medical condition that occurs when there is a narrowing or blockage (stenosis) in the subclavian artery, usually at or near its origin from the aorta. This stenosis causes reduced blood flow to the ipsilateral upper extremity. The decreased blood supply to the arm leads to reversal of flow in the vertebral artery, which normally supplies blood to the brain and neck structures. As a result, the brain may receive insufficient blood flow, causing symptoms such as dizziness, lightheadedness, syncope (fainting), or transient ischemic attacks (TIAs or "mini-strokes").

The syndrome is called 'subclavian steal' because the vertebral artery essentially "steals" blood from the circle of Willis (the network of arteries at the base of the brain) to compensate for the reduced flow in the subclavian artery. The condition most commonly affects the left subclavian artery, but it can also occur on the right side or both sides.

Subclavian Steal Syndrome is typically diagnosed through a combination of physical examination, medical history, and imaging tests such as Doppler ultrasound, CT angiography (CTA), or magnetic resonance angiography (MRA). Treatment options include surgical bypass, endovascular stenting, or medication to manage symptoms and reduce the risk of stroke.

The axillary artery is a major blood vessel in the upper limb. It is the continuation of the subclavian artery and begins at the lateral border of the first rib, where it becomes the brachial artery. The axillary artery supplies oxygenated blood to the upper extremity, chest wall, and breast.

The axillary artery is divided into three parts based on the surrounding structures:

1. First part: From its origin at the lateral border of the first rib to the medial border of the pectoralis minor muscle. It lies deep to the clavicle and is covered by the scalene muscles, the anterior and middle scalene being the most important. The branches arising from this portion are the superior thoracic artery and the thyrocervical trunk.
2. Second part: Behind the pectoralis minor muscle. The branches arising from this portion are the lateral thoracic artery and the subscapular artery.
3. Third part: After leaving the lower border of the pectoralis minor muscle, it becomes the brachial artery. The branches arising from this portion are the anterior circumflex humeral artery and the posterior circumflex humeral artery.

The axillary artery is a common site for surgical interventions such as angioplasty and stenting to treat peripheral arterial disease, as well as for bypass grafting in cases of severe atherosclerosis or occlusion.

A biopsy is a medical procedure in which a small sample of tissue is taken from the body to be examined under a microscope for the presence of disease. This can help doctors diagnose and monitor various medical conditions, such as cancer, infections, or autoimmune disorders. The type of biopsy performed will depend on the location and nature of the suspected condition. Some common types of biopsies include:

1. Incisional biopsy: In this procedure, a surgeon removes a piece of tissue from an abnormal area using a scalpel or other surgical instrument. This type of biopsy is often used when the lesion is too large to be removed entirely during the initial biopsy.

2. Excisional biopsy: An excisional biopsy involves removing the entire abnormal area, along with a margin of healthy tissue surrounding it. This technique is typically employed for smaller lesions or when cancer is suspected.

3. Needle biopsy: A needle biopsy uses a thin, hollow needle to extract cells or fluid from the body. There are two main types of needle biopsies: fine-needle aspiration (FNA) and core needle biopsy. FNA extracts loose cells, while a core needle biopsy removes a small piece of tissue.

4. Punch biopsy: In a punch biopsy, a round, sharp tool is used to remove a small cylindrical sample of skin tissue. This type of biopsy is often used for evaluating rashes or other skin abnormalities.

5. Shave biopsy: During a shave biopsy, a thin slice of tissue is removed from the surface of the skin using a sharp razor-like instrument. This technique is typically used for superficial lesions or growths on the skin.

After the biopsy sample has been collected, it is sent to a laboratory where a pathologist will examine the tissue under a microscope and provide a diagnosis based on their findings. The results of the biopsy can help guide further treatment decisions and determine the best course of action for managing the patient's condition.

Ischemic optic neuropathy (ION) is a medical condition that refers to the damage or death of the optic nerve due to insufficient blood supply. The optic nerve is responsible for transmitting visual information from the eye to the brain.

In ION, the blood vessels that supply the optic nerve become blocked or narrowed, leading to decreased blood flow and oxygen delivery to the nerve fibers. This results in inflammation, swelling, and ultimately, damage to the optic nerve. The damage can cause sudden, painless vision loss, often noticed upon waking up in the morning.

There are two types of ION: anterior ischemic optic neuropathy (AION) and posterior ischemic optic neuropathy (PION). AION affects the front part of the optic nerve, while PION affects the back part of the nerve. AION is further classified into arteritic and non-arteritic types, depending on whether it is caused by giant cell arteritis or not.

Risk factors for ION include age (most commonly occurring in people over 50), hypertension, diabetes, smoking, sleep apnea, and other cardiovascular diseases. Treatment options depend on the type and cause of ION and may include controlling underlying medical conditions, administering corticosteroids, or undergoing surgical procedures to improve blood flow.

Angiography is a medical procedure in which an x-ray image is taken to visualize the internal structure of blood vessels, arteries, or veins. This is done by injecting a radiopaque contrast agent (dye) into the blood vessel using a thin, flexible catheter. The dye makes the blood vessels visible on an x-ray image, allowing doctors to diagnose and treat various medical conditions such as blockages, narrowing, or malformations of the blood vessels.

There are several types of angiography, including:

* Cardiac angiography (also called coronary angiography) - used to examine the blood vessels of the heart
* Cerebral angiography - used to examine the blood vessels of the brain
* Peripheral angiography - used to examine the blood vessels in the limbs or other parts of the body.

Angiography is typically performed by a radiologist, cardiologist, or vascular surgeon in a hospital setting. It can help diagnose conditions such as coronary artery disease, aneurysms, and peripheral arterial disease, among others.

Mucocutaneous Lymph Node Syndrome is also known as Kawasaki Disease. It is a type of vasculitis that primarily affects young children, usually those under the age of 5. The disease is named after Dr. Tomisaku Kawasaki, who first described it in Japan in 1967.

The condition is characterized by inflammation of the mucous membranes (mucosa), skin (cutaneous), and lymph nodes. The symptoms typically include fever, rash, red eyes, swollen lips and tongue, strawberry tongue, and swollen lymph nodes in the neck. In addition, children with Kawasaki disease may also experience joint pain, diarrhea, vomiting, and abdominal pain.

In severe cases, Kawasaki disease can lead to complications such as coronary artery aneurysms, which can increase the risk of heart attacks and other cardiovascular problems. The exact cause of Kawasaki disease is unknown, but it is thought to be triggered by an infection or other environmental factor in genetically susceptible children. Treatment typically involves administering high doses of intravenous immunoglobulin (IVIG) and aspirin to reduce inflammation and prevent complications.

Equine strongyle infections refer to parasitic diseases caused by various species of Strongylus spp. and other related nematode (roundworm) parasites that infect horses. The term "strongyles" is used to describe large and small strongyles, which have different clinical significance and life cycles.

1. Large Strongyles (Strongylus vulgaris, S. edentatus, and S. equinus): These parasites have a significant clinical impact on horses. They have a complex life cycle involving migratory larval stages that travel through the horse's circulatory system and cause damage to blood vessels, heart, liver, and lungs. The adult strongyles reside in the large intestine and lay eggs, which are passed in the feces and further infect the horse upon ingestion of contaminated pasture.
2. Small Strongyles (Cyathostominae subfamily): These parasites have a simpler life cycle and are less clinically significant compared to large strongyles. The larvae encyst within the intestinal wall, where they can remain dormant for extended periods. When environmental conditions become favorable, these larvae emerge from their cysts and mature into adults in the large intestine, causing damage and potentially leading to clinical signs of disease.

Clinical signs of strongyle infections may include diarrhea, colic, weight loss, anemia, and decreased performance. Diagnosis is typically made by identifying parasite eggs in fecal samples using microscopic examination or coprological techniques. Treatment involves the use of anthelmintics (dewormers) specifically labeled for strongyle infections in horses. Preventative measures include pasture management, strategic deworming programs, and regular fecal egg count monitoring to assess parasite burden and treatment efficacy.

The brachiocephalic trunk, also known as the brachiocephalic artery or innominate artery, is a large vessel that branches off the aorta and divides into the right common carotid artery and the right subclavian artery. It supplies blood to the head, neck, and arms on the right side of the body.

Vasculitis is a group of disorders characterized by inflammation of the blood vessels, which can cause changes in the vessel walls including thickening, narrowing, or weakening. These changes can restrict blood flow, leading to organ and tissue damage. The specific symptoms and severity of vasculitis depend on the size and location of the affected blood vessels and the extent of inflammation. Vasculitis can affect any organ system in the body, and its causes can vary, including infections, autoimmune disorders, or exposure to certain medications or chemicals.

Vasculitis, Central Nervous System (CNS), refers to a group of disorders characterized by inflammation of blood vessels within the brain and/or spinal cord. This inflammation can cause damage to the blood vessel walls, leading to narrowing, blocking or weakening of the vessels, and in some cases, formation of aneurysms or rupture of the vessels.

The causes of CNS vasculitis are varied and can include infections, autoimmune diseases, medications, and unknown factors. The symptoms of CNS vasculitis depend on the severity and location of the inflammation, and may include headache, seizures, stroke-like symptoms (such as weakness or numbness in the face, arms, or legs), cognitive changes, and in severe cases, coma.

Diagnosis of CNS vasculitis typically involves a combination of clinical evaluation, imaging studies (such as MRI or angiography), and laboratory tests (including blood tests and analysis of cerebrospinal fluid). Treatment may involve corticosteroids, immunosuppressive medications, and/or other therapies aimed at reducing inflammation and preventing further damage to the blood vessels.

The adrenal cortex hormones are a group of steroid hormones produced and released by the outer portion (cortex) of the adrenal glands, which are located on top of each kidney. These hormones play crucial roles in regulating various physiological processes, including:

1. Glucose metabolism: Cortisol helps control blood sugar levels by increasing glucose production in the liver and reducing its uptake in peripheral tissues.
2. Protein and fat metabolism: Cortisol promotes protein breakdown and fatty acid mobilization, providing essential building blocks for energy production during stressful situations.
3. Immune response regulation: Cortisol suppresses immune function to prevent overactivation and potential damage to the body during stress.
4. Cardiovascular function: Aldosterone regulates electrolyte balance and blood pressure by promoting sodium reabsorption and potassium excretion in the kidneys.
5. Sex hormone production: The adrenal cortex produces small amounts of sex hormones, such as androgens and estrogens, which contribute to sexual development and function.
6. Growth and development: Cortisol plays a role in normal growth and development by influencing the activity of growth-promoting hormones like insulin-like growth factor 1 (IGF-1).

The main adrenal cortex hormones include:

1. Glucocorticoids: Cortisol is the primary glucocorticoid, responsible for regulating metabolism and stress response.
2. Mineralocorticoids: Aldosterone is the primary mineralocorticoid, involved in electrolyte balance and blood pressure regulation.
3. Androgens: Dehydroepiandrosterone (DHEA) and its sulfate derivative (DHEAS) are the most abundant adrenal androgens, contributing to sexual development and function.
4. Estrogens: Small amounts of estrogens are produced by the adrenal cortex, mainly in women.

Disorders related to impaired adrenal cortex hormone production or regulation can lead to various clinical manifestations, such as Addison's disease (adrenal insufficiency), Cushing's syndrome (hypercortisolism), and congenital adrenal hyperplasia (CAH).

Magnetic Resonance Angiography (MRA) is a non-invasive medical imaging technique that uses magnetic fields and radio waves to create detailed images of the blood vessels or arteries within the body. It is a type of Magnetic Resonance Imaging (MRI) that focuses specifically on the circulatory system.

MRA can be used to diagnose and evaluate various conditions related to the blood vessels, such as aneurysms, stenosis (narrowing of the vessel), or the presence of plaques or tumors. It can also be used to plan for surgeries or other treatments related to the vascular system. The procedure does not use radiation and is generally considered safe, although people with certain implants like pacemakers may not be able to have an MRA due to safety concerns.

Aortography is a medical procedure that involves taking X-ray images of the aorta, which is the largest blood vessel in the body. The procedure is usually performed to diagnose or assess various conditions related to the aorta, such as aneurysms, dissections, or blockages.

To perform an aortography, a contrast dye is injected into the aorta through a catheter that is inserted into an artery, typically in the leg or arm. The contrast dye makes the aorta visible on X-ray images, allowing doctors to see its structure and any abnormalities that may be present.

The procedure is usually performed in a hospital or outpatient setting and may require sedation or anesthesia. While aortography can provide valuable diagnostic information, it also carries some risks, such as allergic reactions to the contrast dye, damage to blood vessels, or infection. Therefore, it is typically reserved for situations where other diagnostic tests have been inconclusive or where more invasive treatment may be required.

Anti-inflammatory agents are a class of drugs or substances that reduce inflammation in the body. They work by inhibiting the production of inflammatory mediators, such as prostaglandins and leukotrienes, which are released during an immune response and contribute to symptoms like pain, swelling, redness, and warmth.

There are two main types of anti-inflammatory agents: steroidal and nonsteroidal. Steroidal anti-inflammatory drugs (SAIDs) include corticosteroids, which mimic the effects of hormones produced by the adrenal gland. Nonsteroidal anti-inflammatory drugs (NSAIDs) are a larger group that includes both prescription and over-the-counter medications, such as aspirin, ibuprofen, naproxen, and celecoxib.

While both types of anti-inflammatory agents can be effective in reducing inflammation and relieving symptoms, they differ in their mechanisms of action, side effects, and potential risks. Long-term use of NSAIDs, for example, can increase the risk of gastrointestinal bleeding, kidney damage, and cardiovascular events. Corticosteroids can have significant side effects as well, particularly with long-term use, including weight gain, mood changes, and increased susceptibility to infections.

It's important to use anti-inflammatory agents only as directed by a healthcare provider, and to be aware of potential risks and interactions with other medications or health conditions.

Lactobacillus casei is a species of Gram-positive, rod-shaped bacteria that belongs to the genus Lactobacillus. These bacteria are commonly found in various environments, including the human gastrointestinal tract, and are often used in food production, such as in the fermentation of dairy products like cheese and yogurt.

Lactobacillus casei is known for its ability to produce lactic acid, which gives it the name "lactic acid bacterium." This characteristic makes it an important player in maintaining a healthy gut microbiome, as it helps to lower the pH of the gut and inhibit the growth of harmful bacteria.

In addition to its role in food production and gut health, Lactobacillus casei has been studied for its potential probiotic benefits. Probiotics are live bacteria and yeasts that are beneficial to human health, particularly the digestive system. Some research suggests that Lactobacillus casei may help support the immune system, improve digestion, and alleviate symptoms of certain gastrointestinal disorders like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). However, more research is needed to fully understand its potential health benefits and applications.

Glucocorticoids are a class of steroid hormones that are naturally produced in the adrenal gland, or can be synthetically manufactured. They play an essential role in the metabolism of carbohydrates, proteins, and fats, and have significant anti-inflammatory effects. Glucocorticoids suppress immune responses and inflammation by inhibiting the release of inflammatory mediators from various cells, such as mast cells, eosinophils, and lymphocytes. They are frequently used in medical treatment for a wide range of conditions, including allergies, asthma, rheumatoid arthritis, dermatological disorders, and certain cancers. Prolonged use or high doses of glucocorticoids can lead to several side effects, such as weight gain, mood changes, osteoporosis, and increased susceptibility to infections.

An aneurysm is a localized, balloon-like bulge in the wall of a blood vessel. It occurs when the pressure inside the vessel causes a weakened area to swell and become enlarged. Aneurysms can develop in any blood vessel, but they are most common in arteries at the base of the brain (cerebral aneurysm) and the main artery carrying blood from the heart to the rest of the body (aortic aneurysm).

Aneurysms can be classified as saccular or fusiform, depending on their shape. A saccular aneurysm is a round or oval bulge that projects from the side of a blood vessel, while a fusiform aneurysm is a dilated segment of a blood vessel that is uniform in width and involves all three layers of the arterial wall.

The size and location of an aneurysm can affect its risk of rupture. Generally, larger aneurysms are more likely to rupture than smaller ones. Aneurysms located in areas with high blood pressure or where the vessel branches are also at higher risk of rupture.

Ruptured aneurysms can cause life-threatening bleeding and require immediate medical attention. Symptoms of a ruptured aneurysm may include sudden severe headache, neck stiffness, nausea, vomiting, blurred vision, or loss of consciousness. Unruptured aneurysms may not cause any symptoms and are often discovered during routine imaging tests for other conditions.

Treatment options for aneurysms depend on their size, location, and risk of rupture. Small, unruptured aneurysms may be monitored with regular imaging tests to check for growth or changes. Larger or symptomatic aneurysms may require surgical intervention, such as clipping or coiling, to prevent rupture and reduce the risk of complications.

Arachnoiditis is a medical condition that affects the arachnoid, one of the membranes that surround and protect the nerves of the central nervous system (the brain and spinal cord). The arachnoid becomes inflamed, often as a result of infection, direct injury, or complications from spinal surgery or chronic exposure to irritants such as steroids or contrast dyes.

The inflammation can cause the formation of scar tissue, which can lead to a variety of symptoms including:

1. Chronic pain in the back, legs, or arms
2. Numbness, tingling, or weakness in the limbs
3. Muscle cramps and spasms
4. Bladder and bowel dysfunction
5. Sexual dysfunction

In severe cases, arachnoiditis can cause permanent nerve damage and disability. Treatment typically focuses on managing symptoms and improving quality of life, as there is no cure for the condition.

"AIDS arteritis, central nervous system" is not a widely recognized or formally defined medical term. However, it appears to be a variant of "AIDS dementia complex (ADC)" or "HIV-associated dementia," which refers to a group of neurological disorders that can occur in people with advanced HIV/AIDS.

The term "arteritis" generally refers to inflammation of the arteries, but in the context of ADC, it may refer to the involvement of blood vessels in the brain as part of the disease process. The inflammation and damage to the brain's white matter can lead to cognitive impairment, motor dysfunction, and other neurological symptoms.

It is important to note that HIV/AIDS can affect many different parts of the body and cause a wide range of symptoms. ADC is just one possible complication of advanced HIV/AIDS, and there are many other potential complications as well. If you have any concerns about HIV/AIDS or its potential effects on your health, it is important to speak with a qualified healthcare professional for accurate information and guidance.

Prednisone is a synthetic glucocorticoid, which is a type of corticosteroid hormone. It is primarily used to reduce inflammation in various conditions such as asthma, allergies, arthritis, and autoimmune disorders. Prednisone works by mimicking the effects of natural hormones produced by the adrenal glands, suppressing the immune system's response and reducing the release of substances that cause inflammation.

It is available in oral tablet form and is typically prescribed to be taken at specific times during the day, depending on the condition being treated. Common side effects of prednisone include increased appetite, weight gain, mood changes, insomnia, and easy bruising. Long-term use or high doses can lead to more serious side effects such as osteoporosis, diabetes, cataracts, and increased susceptibility to infections.

Healthcare providers closely monitor patients taking prednisone for extended periods to minimize the risk of adverse effects. It is essential to follow the prescribed dosage regimen and not discontinue the medication abruptly without medical supervision, as this can lead to withdrawal symptoms or a rebound of the underlying condition.

Methylprednisolone is a synthetic glucocorticoid drug, which is a class of hormones that naturally occur in the body and are produced by the adrenal gland. It is often used to treat various medical conditions such as inflammation, allergies, and autoimmune disorders. Methylprednisolone works by reducing the activity of the immune system, which helps to reduce symptoms such as swelling, pain, and redness.

Methylprednisolone is available in several forms, including tablets, oral suspension, and injectable solutions. It may be used for short-term or long-term treatment, depending on the condition being treated. Common side effects of methylprednisolone include increased appetite, weight gain, insomnia, mood changes, and increased susceptibility to infections. Long-term use of methylprednisolone can lead to more serious side effects such as osteoporosis, cataracts, and adrenal suppression.

It is important to note that methylprednisolone should be used under the close supervision of a healthcare provider, as it can cause serious side effects if not used properly. The dosage and duration of treatment will depend on various factors such as the patient's age, weight, medical history, and the condition being treated.

Infarction is the term used in medicine to describe the death of tissue (also known as an "area of necrosis") due to the lack of blood supply. This can occur when a blood vessel that supplies oxygen and nutrients to a particular area of the body becomes blocked or obstructed, leading to the deprivation of oxygen and nutrients necessary for the survival of cells in that region.

The blockage in the blood vessel is usually caused by a clot (thrombus) or an embolus, which is a small particle that travels through the bloodstream and lodges in a smaller vessel. The severity and extent of infarction depend on several factors, including the size and location of the affected blood vessel, the duration of the obstruction, and the presence of collateral circulation (alternative blood vessels that can compensate for the blocked one).

Common examples of infarctions include myocardial infarction (heart attack), cerebral infarction (stroke), and pulmonary infarction (lung tissue death due to obstruction in the lung's blood vessels). Infarctions can lead to various symptoms, depending on the affected organ or tissue, and may require medical intervention to manage complications and prevent further damage.

Retinal artery occlusion (RAO) is a medical condition characterized by the blockage or obstruction of the retinal artery, which supplies oxygenated blood to the retina. This blockage typically occurs due to embolism (a small clot or debris that travels to the retinal artery), thrombosis (blood clot formation in the artery), or vasculitis (inflammation of the blood vessels).

There are two types of retinal artery occlusions:

1. Central Retinal Artery Occlusion (CRAO): This type occurs when the main retinal artery is obstructed, affecting the entire inner layer of the retina. It can lead to severe and sudden vision loss in the affected eye.
2. Branch Retinal Artery Occlusion (BRAO): This type affects a branch of the retinal artery, causing visual field loss in the corresponding area. Although it is less severe than CRAO, it can still result in noticeable vision impairment.

Immediate medical attention is crucial for both types of RAO to improve the chances of recovery and minimize potential damage to the eye and vision. Treatment options may include medications, laser therapy, or surgery, depending on the underlying cause and the severity of the condition.

Blindness is a condition of complete or near-complete vision loss. It can be caused by various factors such as eye diseases, injuries, or birth defects. Total blindness means that a person cannot see anything at all, while near-complete blindness refers to having only light perception or the ability to perceive the direction of light, but not able to discern shapes or forms. Legal blindness is a term used to define a certain level of visual impairment that qualifies an individual for government assistance and benefits; it usually means best corrected visual acuity of 20/200 or worse in the better eye, or a visual field no greater than 20 degrees in diameter.

An aortic aneurysm is a medical condition characterized by the abnormal widening or bulging of the wall of the aorta, which is the largest artery in the body. The aorta carries oxygenated blood from the heart to the rest of the body. When the aortic wall weakens, it can stretch and balloon out, forming an aneurysm.

Aortic aneurysms can occur anywhere along the aorta but are most commonly found in the abdominal section (abdominal aortic aneurysm) or the chest area (thoracic aortic aneurysm). The size and location of the aneurysm, as well as the patient's overall health, determine the risk of rupture and associated complications.

Aneurysms often do not cause symptoms until they become large or rupture. Symptoms may include:

* Pain in the chest, back, or abdomen
* Pulsating sensation in the abdomen
* Difficulty breathing
* Hoarseness
* Coughing or vomiting

Risk factors for aortic aneurysms include age, smoking, high blood pressure, family history, and certain genetic conditions. Treatment options depend on the size and location of the aneurysm and may include monitoring, medication, or surgical repair.

Adie syndrome, also known as Adie's pupil or tonic pupil, is a neurological disorder that affects the autonomic nervous system and the eye. It is characterized by a pupil that is dilated and unresponsive to light, but slowly constricts when focusing on nearby objects (a phenomenon called "light-near dissociation"). This occurs due to damage to the ciliary ganglion or the short ciliary nerves, which control the size of the pupil.

Additional symptoms of Adie syndrome may include decreased deep tendon reflexes, especially in the ankles, and abnormal sweating patterns. The condition is usually not painful and does not typically affect vision, although some people with Adie syndrome may experience difficulty with reading due to the slow pupillary response.

The exact cause of Adie syndrome is unknown, but it is thought to be related to a viral infection or an autoimmune disorder. It is more common in women than men and typically occurs between the ages of 20 and 40. While there is no cure for Adie syndrome, treatment may include the use of glasses with bifocal lenses or reading glasses, as well as physical therapy to improve muscle tone and reflexes.

The renal artery is a pair of blood vessels that originate from the abdominal aorta and supply oxygenated blood to each kidney. These arteries branch into several smaller vessels that provide blood to the various parts of the kidneys, including the renal cortex and medulla. The renal arteries also carry nutrients and other essential components needed for the normal functioning of the kidneys. Any damage or blockage to the renal artery can lead to serious consequences, such as reduced kidney function or even kidney failure.

Togaviridae is a family of enveloped, single-stranded, positive-sense RNA viruses. It includes two genera: Alphavirus and Rubivirus. Alphaviruses are associated with arthritis and encephalitis in humans and animals, while Rubivirus contains only one species, the rubella virus, which is the causative agent of rubella (German measles). These viruses are usually transmitted through insect vectors such as mosquitoes.

The abdominal aorta is the portion of the aorta, which is the largest artery in the body, that runs through the abdomen. It originates from the thoracic aorta at the level of the diaphragm and descends through the abdomen, where it branches off into several smaller arteries that supply blood to the pelvis, legs, and various abdominal organs. The abdominal aorta is typically divided into four segments: the suprarenal, infrarenal, visceral, and parietal portions. Disorders of the abdominal aorta can include aneurysms, atherosclerosis, and dissections, which can have serious consequences if left untreated.

The vasa vasorum are small blood vessels that supply larger blood vessels, such as the arteries and veins, with oxygen and nutrients. They are located in the outer layers (the adventitia and media) of these larger vessels and form a network of vessels that surround and penetrate the walls of the larger vessels. The vasa vasorum are particularly important in supplying blood to the thicker walls of larger arteries, such as the aorta, where diffusion from the lumen may not be sufficient to meet the metabolic needs of the vessel wall.

Ultrasonography, Doppler, color is a type of diagnostic ultrasound technique that uses the Doppler effect to produce visual images of blood flow in vessels and the heart. The Doppler effect is the change in frequency or wavelength of a wave in relation to an observer who is moving relative to the source of the wave. In this context, it refers to the change in frequency of the ultrasound waves as they reflect off moving red blood cells.

In color Doppler ultrasonography, different colors are used to represent the direction and speed of blood flow. Red typically represents blood flowing toward the transducer (the device that sends and receives sound waves), while blue represents blood flowing away from the transducer. The intensity or brightness of the color is proportional to the velocity of blood flow.

Color Doppler ultrasonography is often used in conjunction with grayscale ultrasound imaging, which provides information about the structure and composition of tissues. Together, these techniques can help diagnose a wide range of conditions, including heart disease, blood clots, and abnormalities in blood flow.

Arterial occlusive diseases are medical conditions characterized by the blockage or narrowing of the arteries, which can lead to a reduction in blood flow to various parts of the body. This reduction in blood flow can cause tissue damage and may result in serious complications such as tissue death (gangrene), organ dysfunction, or even death.

The most common cause of arterial occlusive diseases is atherosclerosis, which is the buildup of plaque made up of fat, cholesterol, calcium, and other substances in the inner lining of the artery walls. Over time, this plaque can harden and narrow the arteries, restricting blood flow. Other causes of arterial occlusive diseases include blood clots, emboli (tiny particles that travel through the bloodstream and lodge in smaller vessels), inflammation, trauma, and certain inherited conditions.

Symptoms of arterial occlusive diseases depend on the location and severity of the blockage. Common symptoms include:

* Pain, cramping, or fatigue in the affected limb, often triggered by exercise and relieved by rest (claudication)
* Numbness, tingling, or weakness in the affected limb
* Coldness or discoloration of the skin in the affected area
* Slow-healing sores or wounds on the toes, feet, or legs
* Erectile dysfunction in men

Treatment for arterial occlusive diseases may include lifestyle changes such as quitting smoking, exercising regularly, and eating a healthy diet. Medications to lower cholesterol, control blood pressure, prevent blood clots, or manage pain may also be prescribed. In severe cases, surgical procedures such as angioplasty, stenting, or bypass surgery may be necessary to restore blood flow.

X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.

The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.

CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.

In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.

CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.

In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.

Amaurosis fugax is a medical term that describes a temporary loss of vision in one eye, which is often described as a "shade or curtain falling over the field of vision." It's usually caused by a temporary interruption of blood flow to the retina or optic nerve. This condition is often associated with conditions such as giant cell arteritis, carotid artery stenosis, and cardiovascular disease.

It's important to note that Amaurosis fugax can be a warning sign for a more serious medical event, such as a stroke, so it's essential to seek medical attention promptly if you experience any symptoms of this condition.

The vertebral artery is a major blood vessel that supplies oxygenated blood to the brain and upper spinal cord. It arises from the subclavian artery, then ascends through the transverse processes of several cervical vertebrae before entering the skull through the foramen magnum. Inside the skull, it joins with the opposite vertebral artery to form the basilar artery, which supplies blood to the brainstem and cerebellum. The vertebral artery also gives off several important branches that supply blood to various regions of the brainstem and upper spinal cord.

Aortic valve insufficiency, also known as aortic regurgitation or aortic incompetence, is a cardiac condition in which the aortic valve does not close properly during the contraction phase of the heart cycle. This allows blood to flow back into the left ventricle from the aorta, instead of being pumped out to the rest of the body. As a result, the left ventricle must work harder to maintain adequate cardiac output, which can lead to left ventricular enlargement and heart failure over time if left untreated.

The aortic valve is a trileaflet valve that lies between the left ventricle and the aorta. During systole (the contraction phase of the heart cycle), the aortic valve opens to allow blood to be pumped out of the left ventricle into the aorta and then distributed to the rest of the body. During diastole (the relaxation phase of the heart cycle), the aortic valve closes to prevent blood from flowing back into the left ventricle.

Aortic valve insufficiency can be caused by various conditions, including congenital heart defects, infective endocarditis, rheumatic heart disease, Marfan syndrome, and trauma. Symptoms of aortic valve insufficiency may include shortness of breath, fatigue, chest pain, palpitations, and edema (swelling). Diagnosis is typically made through physical examination, echocardiography, and other imaging studies. Treatment options depend on the severity of the condition and may include medication, surgery to repair or replace the aortic valve, or a combination of both.

A marker vaccine, also known as a "test vaccine" or "immunization tag," is a type of vaccine that not only provides immunity against a particular disease but also contains an antigen that can be detected in bodily fluids (such as blood) after vaccination. This allows for the confirmation of a successful vaccination and the development of immune response in an individual.

Marker vaccines are particularly useful in situations where it is essential to confirm whether a person has been vaccinated or not, such as in disease eradication programs, public health monitoring, or in cases where vaccine-induced immunity needs to be distinguished from natural immunity (due to previous infection). The marker component of the vaccine can be detected through various methods like serological assays or molecular techniques.

An example of a marker vaccine is the oral poliovirus vaccine (OPV), which contains live attenuated polioviruses. After vaccination, the shedding of the weakened viruses in the stool can be detected and used to monitor the effectiveness of immunization campaigns aimed at eradicating polio globally.

The aorta is the largest artery in the human body, which originates from the left ventricle of the heart and carries oxygenated blood to the rest of the body. It can be divided into several parts, including the ascending aorta, aortic arch, and descending aorta. The ascending aorta gives rise to the coronary arteries that supply blood to the heart muscle. The aortic arch gives rise to the brachiocephalic, left common carotid, and left subclavian arteries, which supply blood to the head, neck, and upper extremities. The descending aorta travels through the thorax and abdomen, giving rise to various intercostal, visceral, and renal arteries that supply blood to the chest wall, organs, and kidneys.

The thoracic aorta is the segment of the largest artery in the human body (the aorta) that runs through the chest region (thorax). The thoracic aorta begins at the aortic arch, where it branches off from the ascending aorta, and extends down to the diaphragm, where it becomes the abdominal aorta.

The thoracic aorta is divided into three parts: the ascending aorta, the aortic arch, and the descending aorta. The ascending aorta rises from the left ventricle of the heart and is about 2 inches (5 centimeters) long. The aortic arch curves backward and to the left, giving rise to the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery. The descending thoracic aorta runs downward through the chest, passing through the diaphragm to become the abdominal aorta.

The thoracic aorta supplies oxygenated blood to the upper body, including the head, neck, arms, and chest. It plays a critical role in maintaining blood flow and pressure throughout the body.

Retrospective studies, also known as retrospective research or looking back studies, are a type of observational study that examines data from the past to draw conclusions about possible causal relationships between risk factors and outcomes. In these studies, researchers analyze existing records, medical charts, or previously collected data to test a hypothesis or answer a specific research question.

Retrospective studies can be useful for generating hypotheses and identifying trends, but they have limitations compared to prospective studies, which follow participants forward in time from exposure to outcome. Retrospective studies are subject to biases such as recall bias, selection bias, and information bias, which can affect the validity of the results. Therefore, retrospective studies should be interpreted with caution and used primarily to generate hypotheses for further testing in prospective studies.

Arteries are blood vessels that carry oxygenated blood away from the heart to the rest of the body. They have thick, muscular walls that can withstand the high pressure of blood being pumped out of the heart. Arteries branch off into smaller vessels called arterioles, which further divide into a vast network of tiny capillaries where the exchange of oxygen, nutrients, and waste occurs between the blood and the body's cells. After passing through the capillary network, deoxygenated blood collects in venules, then merges into veins, which return the blood back to the heart.

The scalp is the anatomical region located at the upper part of the human head, covering the skull except for the face and the ears. It is made up of several layers: the skin, the connective tissue, the galea aponeurotica (a strong, flat, tendinous sheet), loose areolar tissue, and the periosteum (the highly vascularized innermost layer that attaches directly to the skull bones). The scalp has a rich blood supply and is home to numerous sensory receptors, including those for touch, pain, and temperature. It also contains hair follicles, sebaceous glands, and sweat glands.

This type of arteritis is most common in females, with a median age of 25 years. Takayasu arteritis is more common in women of ... Arteritis may be primary or secondary to some other disease process. The primary types are: An example of a secondary arteritis ... Arteritis is the inflammation of the walls of arteries, usually as a result of infection or autoimmune response. Arteritis, a ... A complication of arteritis is thrombosis, which can be fatal. Arteritis and phlebitis are forms of vasculitis. Symptoms of ...
Giant cell arteritis causes inflammation and narrowing of the arteries in the head. It often occurs with the disease ... Giant Cell Arteritis (American College of Rheumatology) * Polymyalgia Rheumatica and Giant Cell Arteritis (National Institute ... Giant cell arteritis is a disorder that causes inflammation of your arteries, usually in the scalp, neck, and arms. It narrows ... Giant Cell Arteritis (Genetic and Rare Diseases Information Center) Also in Spanish ...
Arteritis refers to inflammation in your arteries that damages your blood vessels and reduces blood flow to your organs. Learn ... Giant Cell Arteritis (GCA). Giant cell arteritis (GCA), or temporal arteritis, is an inflammation of your superficial temporal ... Takeyasus Arteritis Takeyasus arteritis, also known as aortic arch syndrome or nonspecific aortoarteritis, predominately ... If youve experienced arteritis in the past, you may be at higher risk of experiencing it again. Be on the lookout for ...
... also known as giant-cell arteritis and cranial arteritis, is a systemic vasculitis of medium-sized and large-sized arteries. It ... Temporal arteritis, also known as giant cell arteritis and cranial arteritis, is a systemic vasculitis of medium-sized and ... Temporal Arteritis Pathology. Temporal arteritis: large gap in internal elastic lamina, best seen with elastic stain (Movat ... Temporal Arteritis Pathology. Temporal arteritis: large gap in internal elastic lamina, best seen with elastic stain (Movat ...
Takayasus arteritis can be difficult to treat because the disease may remain active even if your symptoms improve. Its also ... If your primary care doctor suspects that you have Takayasus arteritis, he or she may refer you to one or more specialists ... Treatment of Takayasus arteritis focuses on controlling inflammation with medications and preventing further damage to your ... Understand your condition. Learn everything you can about Takayasus arteritis and its treatment. Know the possible side ...
Takayasus arteritis (pulseless disease) answers are found in the Diagnosaurus powered by Unbound Medicine. Available for ... Takayasus Arteritis (pulseless Disease) [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2023 December 07]. ... Zeiger, Roni F.. "Takayasus Arteritis (pulseless Disease)." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. The Washington ... TY - ELEC T1 - Takayasus arteritis (pulseless disease) ID - 114126 A1 - Zeiger,Roni F, Y1 - 2014/12/01/ BT - Diagnosaurus UR ...
Giant cell arteritis (GCA) is characterized by intimal hyperplasia and luminal obstruction leading to ischemic manifestations ... Pathogenesis of giant cell arteritis: More than just an inflammatory condition? Autoimmun Rev. 2010 Aug;9(10):635-45. doi: ... Giant cell arteritis (GCA) is characterized by intimal hyperplasia and luminal obstruction leading to ischemic manifestations ...
Vivek Patel shares tips on mitigating vision loss in patients with giant cell arteritis. ... Vivek Patel shares tips on mitigating vision loss in patients with giant cell arteritis (GCA). He advises that patients should ...
Retrieved from "https://www.wikidoc.org/index.php?title=Arteritis&oldid=1225705" ...
An increased risk of malignancy was observed in patients with Takayasus arteritis compared to that in the general population ... All newly diagnosed patients with Takayasus arteritis were identified between January 2009 and December 2019. They were ... We identified 1449 newly diagnosed patients with Takayasus arteritis during the observational period (9196 person-years). A ... This study aimed to evaluate the relative risk of malignancy in patients with Takayasus arteritis compared to that in the ...
The US regulator is to quickly review Roche/Genentechs Actemra for the autoimmune disorder, giant cell arteritis (GCA). ...
The American College of Reumatology criteria for the classification of giant cell arteritis. Arteritis Rheum. 1990. 33. 1122. ... Giant cell arteritis. Curr. Opin. Rheumatol. 2002. 14. 3. 10. *4. Martínez-Valle. F. Solans-Laqué. R. Bosch-Gil. J. et al. ... Polymyalgia rheumatica and giant-cell arteritis, Lancet 2008. 372. 234. 245. *18. Lopez-Diaz. M. J. Llorca. J. Gonzalez- ... Giant Cell Arteritis and Arteritic Anterior Ischemic Optic Neuropathies. Written By. Dragos Catalin Jianu and Silviana Nina ...
... Clin Exp ... Objectives: Two main different clinical phenotypes of giant cell arteritis (GCA) have been described, the classic cranial ...
In this case, giant cell arteritis may be indistinguishable from Takayasu arteritis; however, initial treatment for both is ... Takayasu arteritis in Child. Print Images (5) Contributors: Michael Horwich MD, PhD, Nikki Levin MD, Susan Burgin MD, Paritosh ... Takayasu arteritis, also referred to as pulseless disease and aortic arch syndrome, is a rare chronic inflammatory vasculitis ... Giant cell arteritis - typically seen in older patients (mean age 76), rarely causes hypertension, claudication, or bruits; ...
... and best treatments for giant cell arteritis, a major cause of vision loss and other health problems. ... ABSTRACT: Giant cell arteritis (GCA) is a major cause of vision loss and other health problems. Classic histopathological ... Giant cell arteritis (GCA) is the most common form of primary systemic vasculitis. The disease preferentially affects the ... Giant cell arteritis with low erythrocyte sedimentation rate: frequency of occurrence in a population-based study. Arthritis ...
Building upon the collective strength of the vasculitis community, the Foundation supports, inspires and empowers individuals with vasculitis and their families through a wide range of education, research, clinical, and awareness initiatives.. The Vasculitis Foundation is a registered 501 (c) (3) non-profit organization. All contributions are 100% tax-deductible.. ...
ABSTRACT Giant cell arteritis (GCA) is a systemic immune-mediated vasculitis affecting the medium and large arteries. Typical ... Giant cell arteritis (GCA) is a systemic immune-mediated vasculitis affecting the medium and large arteries. Typical symptoms ... This article provides a systematic approach to the diagnosis and management of giant cell arteritis. ...
... ... Clinical Updates in the Treatment of Giant Cell Arteritis: Highlights From Washington, DC. *. ...
Alison Clifford on An approach to giant cell arteritis (GCA), part of a collection of multimedia lectures. ... An approach to giant cell arteritis (GCA). *Dr. Alison Clifford - University of Alberta, Canada ... Clifford, A. (2018, March 29). An approach to giant cell arteritis (GCA) [Video file]. In The Biomedical & Life Sciences ... An approach to giant cell arteritis (GCA). Embed in course/own notes ...
Kawasaki diseaseCoronary artery aneurysmArteritisChildhoodInnate immune responseAcquired immune response ... These results provide new insights into the pathogenesis of KD arteritis that can guide selection of new immunomodulatory ... Abstract Background Kawasaki Disease (KD) can cause potentially life-threatening coronary arteritis in young children, and has ... Transcripts from known infectious agents were not specifically associated with KD coronary arteritis. Conclusions The immune ...
Takayasu Arteritis - Learn about the causes, symptoms, diagnosis & treatment from the Merck Manuals - Medical Consumer Version. ... Symptoms of Takayasu Arteritis Takayasu arteritis is a chronic disorder with symptoms that fluctuate in severity. ... Takayasu Arteritis (Pulseless Disease; Occlusive Thromboaortopathy; Aortic Arch Syndrome; Takayasus Arteritis). By ... Prognosis for Takayasu Arteritis For 20% of people, the disorder occurs once and does not return. For the rest, the disorder ...
Longterm Outcomes of Renal Artery Involvement in Takayasu Arteritis. Seokchan Hong, Byeongzu Ghang, Yong-Gil Kim, Chang-Keun ... Longterm Outcomes of Renal Artery Involvement in Takayasu Arteritis. Seokchan Hong, Byeongzu Ghang, Yong-Gil Kim, Chang-Keun ... A followup study of balloon angioplasty and de-novo stenting in Takayasu arteritis. Int J Cardiol 2000;75 Suppl 1:S147-52. ... Takayasus arteritis and its role in causing renal artery stenosis. Am J Med Sci 2013;346:314-8. ...
The clinical and laboratory course of polymyalgia rheumatica/giant cell arteritis after the first two months of treatment. ... The clinical and laboratory course of polymyalgia rheumatica/giant cell arteritis after the first two months of treatment. ... OBJECTIVES--To examine the clinical course of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) in a prospective ...
This case illustrates that facial swelling may be an under-recognised presenting feature of temporal arteritis, and that a ... Temporal arteritis presenting with facial swelling and a negative temporal artery biopsy ... He was immediately treated for temporal arteritis by commencing systemic corticosteroids. A temporal artery biopsy showed no ... Temporal arteritis presenting with facial swelling and a negative temporal artery biopsy ...
Does preoperative steroid treatment affect the histology in giant cell (cranial) arteritis? ... Does preoperative steroid treatment affect the histology in giant cell (cranial) arteritis? ...
Steroid Responsive Meningitis Arteritis (Call for DNA). By Laura Liscum. Call for PBGVs diagnosed with SRMA for their DNA. ... Steroid responsive meningitis arteritis, also known as neck pain or aseptic meningitis, is an inflammatory disease of the ...
... or temporal arteritis, is an inflammatory disease that affects large blood vessels in the head. Learn about CGA symptoms & ... What Is Giant Cell Arteritis?. Giant cell arteritis - also called temporal arteritis or cranial arteritis - is a disorder in ... Giant cell arteritis (GCA), or temporal arteritis, is not a well-known disease. But its more common than you might think: GCA ... How Giant Cell Arteritis Is Diagnosed. You doctor will start by asking you to describe your symptoms, and will listen for red ...
Lower Frequency of Comorbidities Prior to Onset of Giant Cell Arteritis: A Population-Based Study. Mohanad Elfishawi, Jigisha ... Objective To assess the frequency of comorbidities and metabolic risk factors at and prior to giant cell arteritis (GCA) ... Lower Frequency of Comorbidities Prior to Onset of Giant Cell Arteritis: A Population-Based Study ... Lower Frequency of Comorbidities Prior to Onset of Giant Cell Arteritis: A Population-Based Study ...
Investigational Drugs with Clinical Trials for: Giant Cell Arteritis. ⮩ Send this page by email. ✉ Email this page to a ...
Equine Arteritis Virus (rtPCR). Detection of equine arteritis virus, the causative agent of equine viral arteritis (EVA), by ...
  • Angiography is commonly used in the diagnosis of Takayasu arteritis, especially in the advanced stages of the disease, when arterial stenosis, occlusion, and aneurysms may be observed. (wikipedia.org)
  • However, angiography is a relatively invasive investigation, exposing patients to large doses of radiation, so is not recommended for routine, long-term monitoring of disease progression in patients with Takayasu arteritis. (wikipedia.org)
  • Magnetic resonance angiography is used to diagnose Takayasu arteritis in the early stages, showing changes such as the thickening of the vessel wall. (wikipedia.org)
  • It is also used for long-term monitoring of disease progression in Takayasu arteritis. (wikipedia.org)
  • It includes two types, temporal arteritis and Takayasu arteritis. (wikipedia.org)
  • Takayasu arteritis is more common in women of Asian descent who are in their reproductive years. (wikipedia.org)
  • Takayasu arteritis is an inflammatory disease that mainly affects the larger vessels such as the aorta and its surrounding branches. (wikipedia.org)
  • Research focused on Takayasu arteritis in the western parts of the world remains limited. (wikipedia.org)
  • Background Takayasu arteritis (TAK) is a large vessel vasculitis that rarely affects children. (medscape.com)
  • Takayasu arteritis is an inflammation of large arteries such as the aorta and its major branches . (medlineplus.gov)
  • The cause of Takayasu arteritis is not known. (medlineplus.gov)
  • Takayasu arteritis appears to be an autoimmune condition. (medlineplus.gov)
  • Treatment of Takayasu arteritis is difficult. (medlineplus.gov)
  • Alomari I, Patel PM. Takayasu arteritis. (medlineplus.gov)
  • Takayasu arteritis is rare and difficult to diagnose. (medscape.com)
  • Case reports describe patients who meet the diagnostic criteria for both Takayasu arteritis and giant cell (temporal) arteritis, although subtle differences exist in the distribution of arterial involvement in the two diseases. (medscape.com)
  • Takayasu arteritis: advanced understanding is leading to new horizons. (medscape.com)
  • Trinidad B, Surmachevska N, Lala V. Takayasu Arteritis. (medscape.com)
  • Hata A, Noda M, Moriwaki R, Numano F. Angiographic findings of Takayasu arteritis: new classification. (medscape.com)
  • Numano F, Kobayashi Y. Takayasu arteritis--beyond pulselessness. (medscape.com)
  • Espinoza JL, Ai S, Matsumura I. New Insights on the Pathogenesis of Takayasu Arteritis: Revisiting the Microbial Theory. (medscape.com)
  • The genetics of Takayasu arteritis. (medscape.com)
  • Identification of multiple genetic susceptibility loci in Takayasu arteritis. (medscape.com)
  • Yagi K, Kobayashi J, Yasue S, Yamaguchi M, Shiobara S, Mabuchi H. Four unrelated cases with Takayasu arteritis and CD36 deficiency: possible link between these disorders. (medscape.com)
  • Onen F, Akkoc N. Epidemiology of Takayasu arteritis. (medscape.com)
  • Current status of Takayasu arteritis in India. (medscape.com)
  • Takayasu arteritis (TA) is an immune-mediated disease with an unknown etiology. (nih.gov)
  • Her main areas of interest at present are severe ischemic events in Takayasu arteritis and Behçet's syndrome. (vasculitisfoundation.org)
  • Takayasu arteritis, also known as Takayasu's disease or Takayasu's syndrome, is a rare autoimmune disorder that causes inflammation of the aorta and its major branches. (lavascular.com)
  • Symptoms of Takayasu arteritis typically appear in young women, most commonly between the ages of 20 and 40. (lavascular.com)
  • In some cases, Takayasu arteritis can lead to the development of aneurysms, or bulges, in the aorta or its major branches. (lavascular.com)
  • The cause of Takayasu arteritis is not fully understood, but it is thought to be an autoimmune disorder, in which the body's immune system mistakenly attacks healthy tissue. (lavascular.com)
  • Diagnosis of Takayasu arteritis is typically made based on a combination of clinical symptoms, imaging tests such as CT scans or MRIs, and blood tests. (lavascular.com)
  • While there is no cure for Takayasu arteritis, early diagnosis and treatment can help prevent serious complications , such as aneurysm formation or complete obstruction of the blood vessels. (lavascular.com)
  • It is important for individuals who are at risk for Takayasu arteritis to be monitored by a healthcare provider and receive regular check-ups to ensure the disease is properly managed. (lavascular.com)
  • 2022 American College of Rheumatology/EULAR classification criteria for Takayasu arteritis. (ox.ac.uk)
  • ObjectiveTo develop and validate new classification criteria for Takayasu arteritis (TAK).MethodsPatients with vasculitis or comparator diseases were recruited into an international cohort. (ox.ac.uk)
  • Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial. (nih.gov)
  • Giant cell arteritis contains two different types of arteritides that are almost indistinguishable from one another. (wikipedia.org)
  • Temporal arteritis, the second type of giant cell arteritis, is also a chronic, inflammatory disease involving mid- to large-sized arteries. (wikipedia.org)
  • This condition has many features that are similar to giant cell arteritis or temporal arteritis in older people. (medlineplus.gov)
  • Giant cell arteritis, polymyalgia rheumatica, and takayasu's arteritis. (medlineplus.gov)
  • A rare collaboration of physicists and medical researchers finds a correlation between rheumatoid arthritis and giant cell arteritis and solar cycles. (sciencedaily.com)
  • The results, published in May in BMJ (formerly British Medical Journal ) Open , show a "highly significant" correlation between periodic solar storms and incidence of rheumatoid arthritis (RA) and giant cell arteritis (GCA), two potentially debilitating autoimmune diseases. (sciencedaily.com)
  • What is the maximum recommended delay for obtaining a temporal artery biopsy after initiation of corticosteroids in patients with suspected giant cell arteritis? (aafp.org)
  • Corticosteroid therapy in patients with suspected giant cell arteritis should not degrade the accuracy of temporal artery biopsy if the biopsy is performed within four weeks of corticosteroid initiation. (aafp.org)
  • A 2002 prospective randomized controlled trial enrolled patients with at least three of the four American College of Rheumatology clinical criteria for giant cell arteritis who had not started corticosteroid therapy. (aafp.org)
  • 2 Data from 535 consecutive patients who underwent biopsy for suspected giant cell arteritis were reexamined by experienced pathologists blinded to clinical data, previous corticosteroid therapy, and original pathologic diagnosis. (aafp.org)
  • 3 Giant cell arteritis was diagnosed by positive biopsy or the presence of all four clinical criteria. (aafp.org)
  • A retrospective case-control study in 2012 evaluated 335 patients with suspected giant cell arteritis, 81 of whom had a positive temporal artery biopsy. (aafp.org)
  • 5 Neither the American College of Rheumatology nor the American Academy of Ophthalmology has endorsed practice recommendations for the diagnosis of giant cell arteritis. (aafp.org)
  • Giant cell arteritis affects the blood supply to the scalp, jaw muscles or the back of the eye. (rheumatology.org.uk)
  • Silent versus cranial giant cell arteritis. (nih.gov)
  • BACKGROUND: The objective of the present study was to compare the silent form of giant cell arteritis (GCA) to the classic cephalic form of the disease. (nih.gov)
  • Tolosa-Hunt syndrome mimicking giant cell arteritis. (jrheum.org)
  • Necrotizing arteritis with giant cells, involving the aorta, pulmonary and coronary arteries, and coronary, splenic, and renal arterioles was found at necropsy in a 74-year-old male who had died with severe haemolytic anaemia associated with cold haemagglutinins. (bmj.com)
  • The clinical and pathological features of this case are shared by well-recognized forms of necrotizing angiitis, in particular giant cell arteritis, but do not conform satisfactorily with any of these disorders. (bmj.com)
  • This resource contains general information about polymyalgia rheumatica and giant cell arteritis. (nih.gov)
  • It describes symptoms and causes, as well as information about diagnosis, treatment, and other strategies for living with polymyalgia rheumatica and giant cell arteritis. (nih.gov)
  • Cranial (temporal or giant-cell) arteritis is a debilitating condition commonest in those aged over 70 years and therefore likely to become more widespread as this population increases. (bmj.com)
  • Background Giant cell arteritis (GCA), if untreated, can lead to blindness and stroke. (whiterose.ac.uk)
  • Deflazacort versus prednisone in patients with giant cell arteritis: effects on bone mass loss. (jrheum.org)
  • OBJECTIVE: To compare bone mass loss due to deflazacort versus prednisone in longterm treatment of patients with giant cell arteritis (GCA) in a randomized double blind comparative trial. (jrheum.org)
  • What are the symptoms of giant cell arteritis? (msdmanuals.com)
  • Symptoms of giant cell arteritis may start suddenly or come on slowly over several weeks. (msdmanuals.com)
  • Rarely, giant cell arteritis affects your aorta, the main artery coming out of your heart. (msdmanuals.com)
  • How can doctors tell if I have giant cell arteritis? (msdmanuals.com)
  • How do doctors treat giant cell arteritis? (msdmanuals.com)
  • Cranial ischaemic events constitute a significant component in the clinical spectrum of giant cell arteritis (GCA). (clinexprheumatol.org)
  • Importance Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are related inflammatory disorders occurring in persons aged 50 years and older. (jamanetwork.com)
  • Giant cell arteritis is the most common primary systemic vasculitis in adults aged ≥50 years and peaks in the eighth decade of life. (nervegarden.com)
  • Giant cell arteritis (GCA) is the most common of all the vas-culitides. (nervegarden.com)
  • 1. Giant cell arteritis, also called temporal arteritis, is a disease that causes your arteries -- blood vessels that carry oxygen from your heart to the rest of your body -- to become inflamed. (nervegarden.com)
  • Giant cell arteritis is also known as temporal arteritis. (nervegarden.com)
  • Giant cell arteritis is vasculitis of unknown cause that affects the elderly and is characterized by panarteritis of medium- to large-sized arteries, especially in the extracranial branches of the carotid artery. (nervegarden.com)
  • Efficacy of unilateral versus bilateral temporal artery biopsies for the diagnosis of giant cell arteritis. (nervegarden.com)
  • Giant cell arteritis also can affect extracranial and intracranial blood vessels and produce homonymous loss of the visual field (i.e. (nervegarden.com)
  • PURPOSE: To determine the utility of unilateral versus bilateral temporal artery biopsies in detecting the pathologic changes of giant cell arteritis. (nervegarden.com)
  • Bilateral simultaneous PION does not exclusively occur in a post surgical setting, emphasizing the importance of decreasing the threshold of suspicion of similar cases to avoid further neurological complica … Simultaneous bilateral posterior ischemic optic neuropathy secondary to giant cell arteritis: a case presentation and review of the literature BMC Ophthalmol. (nervegarden.com)
  • Giant cell arteritis (GCA), or temporal arteritis, is a systemic inflammatory vasculitis of unknown etiology that occurs in older persons and can result in a wide variety of systemic, neurologic, and ophthalmologic complications. (nervegarden.com)
  • Giant Cell (Temporal) Arteritis with Persistent Bilateral Sensorineural Hearing Loss - A Likely Consequence of Delayed Institution of Glucocorticoid Therapy. (nervegarden.com)
  • Case Report: A 62-year-old female patient presented with bilateral progressive vision loss was diagnosed with bilateral posterior scleritis.According to clinical signs and symptoms and laboratory testing, Giant cell arteritis was also diagnosed. (nervegarden.com)
  • Patients with extracranial giant cell arteritis present with occlusive arterial lesions that may be detected with several imaging modalities: angiography, CT scanning or magnetic resonance angiography (MRA). (nervegarden.com)
  • Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that affects adults above 50 years of age. (rug.nl)
  • Giant Cell Arteritis (GCA), also known as Temporal Arteritis, is an autoimmune condition that causes inflammation in both large and medium sized blood vessels, a process called vasculitis. (albertarheumatology.com)
  • GCA typically occurs in people 50 years of age or … Criteria for the classification of giant cell (tem- poral) arteritis were developed by comparing 214 pa- tients who had this disease with 593 patients with other forms of vasculitis. (ourdigitalheroes.org)
  • all entry criteria, the diagnosis of Giant cell arteritis can be establis hed. (ourdigitalheroes.org)
  • The American College of Rheumatology criteria for the classification of giant cell arteritis may assist in the diagnosis. (ourdigitalheroes.org)
  • Temporal arteritis (giant cell arteritis) is where the arteries, particularly those at the side of the head (the temples), become inflamed. (ourdigitalheroes.org)
  • Giant cell arteritis can be difficult to diagnose because its early symptoms resemble those of other common conditions. (ourdigitalheroes.org)
  • For the traditional format classifica- tion, 5 criteria were selected: age 150 years at disease onset, new … The American College of Rheumatology criteria for the classification of giant cell arteritis may assist in the diagnosis. (ourdigitalheroes.org)
  • PURPOSE: To ascertain the validity, reliability, sensitivity, and specificity of various signs and symptoms of and diagnostic tests for early diagno sis of giant cell arteritis. (ourdigitalheroes.org)
  • Giant cell arteritis is a chronic inflammatory disease characterized by the progressive inflammation of many arteries of the body (panarteritis). (ourdigitalheroes.org)
  • For purposes of classification, a patient shall be said to have giant cell (temporal) arteritis if at least 3 of these 5 criteria are present. (ourdigitalheroes.org)
  • Giant cell arteritis (GCA) also known as temporal arteritis is a sight- and life-threatening, granulomatous large-vessel condition. (lu.se)
  • Giant cell arteritis is a large vessel vasculitis of the arteries in the head and neck. (medscape.com)
  • Therefore, when tocilizumab was approved for up to 1 year for cases of relapsing or refractory giant cell arteritis by the National Institute of Health and Care Excellence (NICE) in April 2018, this offered an opportunity to benefit from new funding and to reduce steroid burden. (medscape.com)
  • This case series describes the impact of the establishment of a new hub and spoke referral pathway for the use of tocilizumab in refractory or relapsing giant cell arteritis, with case examples from consecutive patients who accessed the funding between August 2018 and April 2021. (medscape.com)
  • Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) is inflammation of the arteries in the arms, upper body, neck, hips,… What are giant cell arteritis (GCA) and polymyalgia rheumatic (PMR)? (familydoctor.org)
  • Giant cell arteritis is a form of vasculitis involving the medium- and large-sized arteries that chiefly affects older people. (medihelp.life)
  • Giant cell arteritis (GCA) is primarily a disease of cell-mediated immunity, which is thought to arise as a maladaptive response to endothelial injury. (medscape.com)
  • Giant cell arteritis affects the aorta, which brings blood to every branch of the body, including the arms, legs, and head. (nih.gov)
  • Giant cell arteritis typically occurs in people age 50 years and older. (nih.gov)
  • The purpose of this study is to find out if advanced ultrasound studies can be used to make a diagnosis of giant cell arteritis. (mayoclinic.org)
  • Ultimately, we hope to be able to offer non-invasive diagnostic options as an alternative to biopsy to future patients who are being evaluated for giant cell arteritis. (mayoclinic.org)
  • A 76-year old African American female with a history of arteritic ischemic optic neuropathy (AION) secondary to biopsy-proven giant cell arteritis (GCA) presented with unilateral vision loss in her contralateral eye despite high-dose oral steroid treatment. (springeropen.com)
  • A 76-year-old woman with a history of hypertension, non-insulin dependent type 2 diabetes, stroke, and arteritic ischemic optic neuropathy (AION) of the left eye due to biopsy-proven giant cell arteritis (GCA) presented with painless, diffuse vision loss in the right eye for the past 10 days despite current high-dose oral steroid treatment (0.75 mg/kg/day prednisone). (springeropen.com)
  • Arteritis is the inflammation of the walls of arteries, usually as a result of infection or autoimmune response. (wikipedia.org)
  • Arteritis is inflammation of your arteries. (msdmanuals.com)
  • The symptoms of temporal arteritis depend on which arteries are affected. (ourdigitalheroes.org)
  • Additionally, Takayasu's arteritis or other forms of large-vessel vasculitis must be considered either in patients incidentally found to have findings suspicious for vasculitis on imaging obtained for other clinical indications or when vasculitis is found on histologic examination of surgically removed segments of arteries. (lavascular.com)
  • I think GCA is a better name than Temperal Arteritis, as it affects more than just head arteries. (mayoclinic.org)
  • [ 3 ] but typically also involves medium and small arteries, particularly the superficial temporal arteries-hence the term temporal arteritis. (medscape.com)
  • Arteries in the head and neck become inflamed with temporal arteritis . (medicalnewstoday.com)
  • Fluorescein angiography showed slowed arteriolar filling with late staining of small peripheral arteries, consistent with small vessel arteritis. (springeropen.com)
  • Symptoms of general arteritis may include: Inflammation Fever Increased production of red blood cells (erythrocytes) Limping Reduced pulse Diagnosis of arteritis is based on unusual medical symptoms. (wikipedia.org)
  • Ultrasonography is an ideal method of diagnosing patients in early stages of arteritis when inflammation in the vessel walls occurs. (wikipedia.org)
  • Aggarwal A, Chag M, Sinha N, Naik S. Takayasu's arteritis: role of Mycobacterium tuberculosis and its 65 kDa heat shock protein. (medscape.com)
  • Kumar Chauhan S, Kumar Tripathy N, Sinha N, Singh M, Nityanand S. Cellular and humoral immune responses to mycobacterial heat shock protein-65 and its human homologue in Takayasu's arteritis. (medscape.com)
  • Takayasu's arteritis is an uncommon chronic vasculitis of unknown etiology, which primarily affects the aorta and its primary branches. (lavascular.com)
  • The pathogenesis of Takayasu's arteritis is poorly understood. (lavascular.com)
  • The onset of symptoms in Takayasu's arteritis tends to be subacute, which often leads to a delay in diagnosis that can range from months to years, during which time vascular disease may start and progress. (lavascular.com)
  • The physical examination of a patients with Takayasu's arteritis should particularly focus on accurate measurements of blood pressure , palpation of pulses, identification of bruits, and careful cardiac auscultation. (lavascular.com)
  • The diagnosis of Takayasu's arteritis should be suspected in a patient who has constitutional symptoms, hypertension , diminished or absent pulses, and/or arterial bruits. (lavascular.com)
  • We sought to distinguish a silent form, defined by a prolonged inflammatory syndrome or fever of unknown origin with the absence of cephalic signs, polymyalgia rheumatica, or large artery involvement, from an overt "classic" cranial temporal arteritis. (nih.gov)
  • It's sometimes called temporal arteritis because it very often affects an artery on your temple (the side of your head). (msdmanuals.com)
  • Equine viral arteritis is a contagious, viral disease that affects members of the horse family. (msdvetmanual.com)
  • Symptoms of temporal arteritis are classified as specific and nonspecific. (wikipedia.org)
  • Nonspecific symptoms: Headache Low grade fever Sweating Anorexia (loss of appetite) Weight loss General malaise Specific symptoms: Claudication of the jaw Engorged, tender vessels Specific symptoms usually develop in the advanced stages of temporal arteritis. (wikipedia.org)
  • Arteritis may be distinguished by its different types, based on the organ systems affected by the disease. (wikipedia.org)
  • Arteritis may be primary or secondary to some other disease process. (wikipedia.org)
  • Blau arteritis resembling Takayasu disease with a novel NOD2 mutation. (jefferson.edu)
  • The disease is caused by the equine arteritis virus and is of short duration. (msdvetmanual.com)
  • Other names for GCA include arteritis cranialis, Horton disease, granulomatous arteritis, and arteritis of the aged. (medscape.com)
  • Computed tomography angiography can determine the size of the aorta and its surrounding branches, and can identify vessel wall lesions in middle to late stages of arteritis. (wikipedia.org)
  • Equine viral arteritis (EVA) is a cause of concern for horse owners and breeders, but luckily it is a manageable issue. (aqha.com)
  • Depression in a horse with equine viral arteritis. (merckvetmanual.com)
  • Transmission of the virus is not always associated with the appearance of the signs characteristic of equine viral arteritis. (msdvetmanual.com)
  • Electroencephalograph (EEG) demonstrated examination showed chronic granulomatous meningitis intermittent irregular slow delta waves in the right frontal and arteritis. (cdc.gov)
  • Coronary arteritis in Wegener's granulomatosis causing fatal myocardial infarction. (ox.ac.uk)
  • Superficial temporal artery biopsy (TAB) is the criterion standard for diagnosing temporal arteritis. (medscape.com)
  • Longitudinal section of a temporal artery biopsy that is negative (GCA-) and positive (GCA+) för arteritis. (lu.se)
  • The primary types are: An example of a secondary arteritis is arteritis caused by infection with the fungal pathogen Candida albicans. (wikipedia.org)
  • Temporal arteritis is not uncommon in North America. (wikipedia.org)
  • A logistic regression model controlling for clinical features suggestive of arteritis showed no difference in the rate of positive biopsies based on treatment delay. (aafp.org)
  • Arteritis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (jefferson.edu)
  • It is often associated with aneurysms and Hepatitis B. The first-line treatment for arteritis is oral glucocorticoid (steroid) medication, such as prednisone, taken daily for a period of three months. (wikipedia.org)

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