Basal Ganglia Cerebrovascular Disease

Basal Ganglia

Cerebrovascular Disorders

Basal Ganglia Diseases

Ganglia

List of MeSH codes (C10)

List of MeSH codes (C14)

Spasmodic torticollis

Perivascular space

Catatonia

List of women neuroscientists

HIV-associated neurocognitive disorder

Hypertension and the brain

Intracerebral hemorrhage

Glutaric aciduria type 1

Anosognosia

Amnesia

Memory disorder

Intracranial aneurysm

Cerebral palsy

Cinnarizine

Charcot-Bouchard aneurysm

Dysprosody

Aging brain

Binswanger's disease

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy

Cerebral atrophy

CADASIL

Differential diagnoses of anorexia nervosa

Intraparenchymal hemorrhage

Cholinergic neuron

Amyloid plaques

Aphasia

Glossary of medicine

Neurobiological effects of physical exercise

HEMORRHAGE1

• Moyamoya disease is an idiopathic, nonatherosclerotic, noninflammatory, chronic progressive cerebrovascular disease characterized by bilateral stenosis or occlusion of the arteries around the circle of Willis, typically the supraclinoid internal carotid arteries, followed by extensive collateralization, which are prone to thrombosis, aneurysm, and hemorrhage. (jpgmonline.com)

Disorders6

• 1 Recovery from cerebrovascular disorders in animals is probably more spectacular than in humans because animals have a less prominent pyramidal system. (vin.com)
• Mehanna R. and Jankovic J. Movement disorders in cerebrovascular diseases. (eso-stroke.org)
• Overview of Movement and Cerebellar Disorders Voluntary movement requires complex interaction of the corticospinal (pyramidal) tracts, basal ganglia, and cerebellum (the center for motor coordination) to ensure smooth, purposeful movement. (msdmanuals.com)
• Depressive disorders do not exhibit manic or hypomanic components characteristic of bipolar disease. (pharmacology2000.com)
• In classic cases, CADASIL manifests with headaches, repeated cerebrovascular disorders, and progressive cognitive decline. (annaly-nevrologii.com)
• This group includes lysosomal storage disorders, various mitochondrial diseases, other neurometabolic disorders, and several other miscellaneous disorders. (medscape.com)

Neurodegenerative diseases3

• Parkinson disease is by far the most common cause of the parkinsonian syndrome , accounting for approximately 80% of cases (the remainder being due to other neurodegenerative diseases, such as Lewy body dementia ) 1 . (radiopaedia.org)
• Multiple neuropathologic processes may underlie dementia , including both neurodegenerative diseases and vascular disease. (medscape.com)
• As with many neurodegenerative diseases, both rare autosomal-dominant forms of AD and more common sporadic forms with genetic risk factors without causative mutations exist. (medscape.com)

Brainstem4

• It has an association with cerebrovascular disease and develops when strokes affect a specific area of the brainstem called the basal ganglia, which is involved in motor coordination and muscle tone. (medicalnewstoday.com)
• A number of other regions including parts of the basal ganglia , brainstem , autonomic nervous system and cerebral cortex 3 . (radiopaedia.org)
• Cerebral magnetic resonance imaging plays an important diagnostic role as it reveals multiple lacunar infarcts in the basal ganglia, brainstem, and cerebellum, as well as focal white matter lesions and diffuse leukoaraiosis changes. (annaly-nevrologii.com)
• Neurological causes: These include cerebrovascular accidents (CVA) such as hemispheric or brainstem stroke leading to post-stroke dysphagia. (doctorable.com)

Intracranial2

• Intracranial atherosclerotic disease and severe tooth loss and in community-dwelling older adults. (gob.ec)
• Information on the association between tooth loss and intracranial atherosclerotic disease (ICAD) is limited. (gob.ec)

Lesions7

• thus, lesions involving cortico-striatal fibers may disrupt the balance of basal ganglia circuits. (eso-stroke.org)
• The significance of small cerebrovascular lesions is frequently overlooked in patients with Alzheimer's disease. (lidsen.com)
• These lesions are most commonly due to cerebral amyloid angiopathy, which is mainly associated in the end-stages of the disease. (lidsen.com)
• The most common small cerebrovascular lesions are cortical micro-bleeds, cortical micro-infarcts, white matter changes, lacunar infarcts and superficial cortical siderosis. (lidsen.com)
• These lesions can be best detected with 7.0-tesla magnetic resonance imaging in vivo and on post-mortem examination, when the diagnosis of Alzheimer's disease has to be confirmed for the family. (lidsen.com)
• Neuroimaging revealed chronic microangiopathic cerebral disease with lesions in the periventricular and deep subcortical white matter regions along with deep cerebral infarct lesions in the left centrum semiovale and basal ganglia, encompassing the bilateral thalamic and striatocapsular infarctions ( Fig. 1 , 2 ). (e-agmr.org)
• Parkinson's disease is also an important cause of dysphagia that is due to basal ganglia lesions. (doctorable.com)

Stroke13

• According to a 2019 article , if the stroke affects the basal ganglia on one side of the brain, a person will experience symptoms on the opposite side of the body. (medicalnewstoday.com)
• However, it can affect both sides of the body if the stroke affects both sides of the basal ganglia. (medicalnewstoday.com)
• 2 A 'stroke' is a suddenly developing focal neurological deficit resulting from a cerebrovascular accident. (vin.com)
• The individual approach combines a vascular risk factor modification and various therapies addressing the specific subtypes of stroke (eg, antiplatelet drugs to prevent cerebral infarction in large and small artery diseases of the brain, carotid endarterectomy or stenting for tight carotid artery stenosis, and oral anticoagulants to prevent cardiac emboli). (medscape.com)
• Management of vascular disease and dementia in a young patient with suspected uncommon causes of stroke (eg, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy [CADASIL] or angiitis) involves ruling out these conditions with the appropriate testing procedures (ie, skin biopsy, cerebral angiography). (medscape.com)
• Genetic and acquired hypercoagulable states, such as factor V Leiden deficiency, prothrombin G20210A mutation, and antiphospholipid syndrome, are associated with cerebrovascular events, including cerebral venous thrombosis and ischemic stroke. (medlink.com)
• Cerebrovascular manifestations of a hypercoagulable state are arterial ischemic stroke and cerebral venous thrombosis. (medlink.com)
• A 64-year-old retired female patient with several cerebrovascular risk factors, including a history of hypertension, dyslipidemia, diabetes, mild cognitive decline, and an ischemic stroke that had occurred more than 3 years ago with grade 4 hemiparesis on the right side and hearing loss as sequelae, was admitted to our psychiatric ward because of a psychotic episode with a two-stage progression. (e-agmr.org)
• There seems to be a predilection for the basal ganglia in ischemic stroke following cannabis abuse. (ruralneuropractice.com)
• Since MMS is a progressive disease, it is important to diagnose and initiate treatment to prevent worsening of the disease and recurrence of stroke. (jpgmonline.com)
• Although moyamoya disease (MMD) is a common cause of transient ischemic stroke in Asian children and young adults, there have been very few cases of MMS in thalassemia published in the literature. (jpgmonline.com)
• Diffusion-weighted imaging did not reveal abnormal restricted diffusion ruling out an acute basal ganglia stroke. (jpgmonline.com)
• Women who experience more hot flashes, particularly while sleeping, during the menopause transition are more likely to have brain changes reflecting a higher risk for cerebrovascular disease, such as stroke and other brain blood flow problems, according to a pilot study led by researchers at the University of Pittsburgh. (health-innovations.org)

Lacunar2

• Neuroimaging revealed basal ganglia lacunar infarctions along with chronic white matter small-vessel ischemic disease. (e-agmr.org)
• 10 enlarged basal ganglia perivascular spaces, and both lacunar and non-lacunar strokes. (gob.ec)

Dementia7

• Vascular dementia is a heterogeneous entity with a large clinicopathological spectrum that has been classically linked to cortical and subcortical ischemic changes resulting from systemic, cardiac, or local large- or small-vessel disease occlusion. (medscape.com)
• In a clinical setting, differences between the cognitive disturbances in vascular dementia and Alzheimer disease are of limited value in distinguishing the 2 conditions. (medscape.com)
• Vascular dementia may have less significant memory dysfunction than Alzheimer disease. (medscape.com)
• Dementia with Lewy Bodies and Parkinson Disease Dementia Lewy body dementia includes clinically diagnosed dementia with Lewy bodies and Parkinson disease dementia. (msdmanuals.com)
• Parkinson disease may share features of other synucleinopathies, such as autonomic dysfunction and dementia. (msdmanuals.com)
• [ 2 ] All dementia share common molecular mechanisms responsible for disease etiology and progression, such as hypoxia and oxidative stress, neuroinflammation, mitochondrial bioenergetics, neurodegeneration, and blood-brain barrier permeability. (medscape.com)
• Alzheimer disease (AD) is the most common neurodegenerative disease responsible for dementia. (medscape.com)

Pathophysiology1

• This case adds to the growing body of evidence pertaining to the relevance of cerebrovascular risk factors in the pathophysiology of VLOSLP, alongside age-specific neurobiological processes. (e-agmr.org)

Thalamus2

• The basal ganglia, thalamus, and subthalamic region were intact. (eso-stroke.org)
• In particular, anterior parietal strokes, without any evidence of involvement of the basal ganglia, thalamus or subthalamic nucleus, have been associated with contralateral hemiballism 5 . (eso-stroke.org)

20211

• He's been in the hospital in Tacloban City, Philippines due to Acute Cerebrovascular Disease Bleed in his left basal ganglia and health care associated pneumonia since July 10, 2021 and was discharged last July 24, 2021 but unfortunately we rushed him back to the hospital next day after, July 25, 2021 due to rebleeding and had an emergency surgery. (gogetfunding.com)

Neurological2

• Paroxysmal dyskinesias are a group of neurological diseases characterized by intermittent episodes of involuntary movements with different causes. (biomedcentral.com)
• Multiple sclerosis is a common, chronic demyelinating neurological disease primarily affecting young adults, with a prevalence of ~0.1% in the Caucasian population (Miller and Leary, 2007). (medscape.com)

Bilateral1

• Depicted clusters are (1) the bilateral insula, (2) the brain stem, (3) the basal ganglia, (4) the anterior cingulate cortex, and (5) the dorsal prefrontal cortex. (health-innovations.org)

Parkinson14

• Parkinson disease is a slowly progressive, degenerative disorder characterized by resting tremor, stiffness (rigidity), slow and decreased movement (bradykinesia), and eventually gait and/or postural instability. (msdmanuals.com)
• Parkinson disease is usually idiopathic. (msdmanuals.com)
• Onset between ages 21 and 40 years is sometimes called young or early-onset Parkinson disease. (msdmanuals.com)
• is brain dysfunction that is characterized by basal ganglia dopaminergic blockade and that is similar to Parkinson disease, but it is caused by something other than Parkinson disease (eg, drugs, cerebrovascular disease, trauma, postencephalitic changes). (msdmanuals.com)
• Lewy bodies appear in a temporal sequence, and many experts believe that Parkinson disease is a relatively late development in a systemic synucleinopathy. (msdmanuals.com)
• Parkinson disease (PD) , also known as idiopathic parkinsonism , is a neurodegenerative disease and movement disorder characterized by resting tremor, rigidity and hypokinesia due to progressive degeneration of dopaminergic neurons in the substantia nigra . (radiopaedia.org)
• A juvenile form of Parkinson disease is also recognized, manifesting between 20-40 years of age 1 . (radiopaedia.org)
• Parkinson disease is characterized by both motor and non-motor clinical features. (radiopaedia.org)
• The dopaminergic tract is predominantly affected in Parkinson disease, and histologically, it is characterized by nigrostriatal dopaminergic degeneration leading to neuronal loss in the substantia nigra pars compacta (SNpc), most conspicuous in the ventrolateral tier of neurons 11 . (radiopaedia.org)
• At least eleven genes have been implicated in various forms of Parkinson disease 3 . (radiopaedia.org)
• For example, juvenile Parkinson disease has been linked to mutations in the PARK2 gene, which encodes for the enzyme ubiquitin ligase-L3. (radiopaedia.org)
• In patients with juvenile Parkinson disease, its function is impaired, and the formation of Lewy bodies is impossible. (radiopaedia.org)
• Few studies have examined the relationship between cerebrovascular disease, vascular risk factors and Parkinson disease (PD), although one study found small vessel disease (SVD) to be the main subtype of cerebrovascular disease. (edu.au)
• Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. (sdsu.edu)

Occlusion1

• Neuroimaging studies of the brain revealed infarcts in basal ganglia secondary to occlusion of blood flow in the left anterior and middle cerebral arteries. (ruralneuropractice.com)

Small-vessel ischemic disease2

• Furthermore, there is a lack of investigations into how WMHs attributable to migraine might be distinguishable from those attributed to other etiologies, such as small vessel ischemic disease and demyelinating disease. (frontiersin.org)
• This study aimed to categorize WMHs in patients with migraine by their size and location, so as to allow for future differentiation of migraine-specific WMHs from those attributable to other diseases, such as small vessel ischemic disease and multiple sclerosis. (frontiersin.org)

Acute1

• CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)

Infarcts5

• CBAs were rare and predominantly seen in elderly individuals, many of whom had multiple systemic and cerebrovascular comorbidities including hypertension, myocardial and cerebral infarcts, and CAA. (nature.com)
• Two CBAs in the basal ganglia demonstrated associated microhemorrhages, while three demonstrated infarcts in the vicinity. (nature.com)
• lt;p>Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary CNS disease with autosomal dominant inheritance caused by NOTCH3 gene mutations. (annaly-nevrologii.com)
• Choi J. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: a genetic cause of cerebral small vessel disease. (annaly-nevrologii.com)
• Therefore, cannabis abuse should be considered in young adults with basal ganglia infarcts, after excluding other known etiologies. (ruralneuropractice.com)

Dopaminergic1

• These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA. (sdsu.edu)

Strokes2

• Vascular Parkinson's (VP) disease is a condition that occurs due to one or more small strokes in a specific area of the brain. (medicalnewstoday.com)
• VP happens when a reduced blood supply to the brain causes one or more strokes that damage the basal ganglia. (medicalnewstoday.com)

Thalamic1

• These areas are the cerebral cortex, the hippocampus, the amygdala, several basal and thalamic nuclei, and the cerebellar cortical Purkinje cells. (vin.com)

Periventricular3

• Both neurodegenerative 1 ) and cerebrovascular processes have been proposed, given the common neuroimaging findings of white matter hyperintensity, particularly in the periventricular regions. (e-agmr.org)
• This study assessed WMH in patients with migraine using a modified version of the Scheltens visual rating scale, a semiquantitative scale for categorizing WMH in periventricular, lobar, basal ganglia, and infratentorial regions. (frontiersin.org)
• The goal of this study was to assess WMHs in patients with migraine using a modified version of the Scheltens visual rating scale ( 13 ), a well-known semi-quantitative rating scale for assessing WMHs in the following brain regions: periventricular, lobar, basal ganglia, and infratentorial (as shown in Figure 1 ). (frontiersin.org)

MEYNERT1

• However, synuclein can accumulate in many other parts of the nervous system, including the dorsal motor nucleus of the vagus nerve, basal nucleus of Meynert, hypothalamus, neocortex, olfactory bulb, sympathetic ganglia, and myenteric plexus of the gastrointestinal tract. (msdmanuals.com)

Manifestations1

• This review highlights new information regarding the virology, clinical manifestations, and pathology of WNV disease, which will provide a new platform for further research into diagnosis, treatment, and possible prevention of WNV through vaccination. (cdc.gov)

Suspected Alzheimer's disease1

• The final message is that in patients with suspected Alzheimer's disease the vascular risk factors, such as arterial hypertension, hypercholesterolemia and diabetes, have to be treated as early as possible and smoking has to be avoided. (lidsen.com)

Alzheimer's4

• In mild-to-moderate Alzheimer's disease patients, it has been shown that hippocampal volumes are 27% smaller than in normal elderly controls [ 10 , 11 ], whereas patients with MCI show a volume reduction of 11% [ 11 ]. (hindawi.com)
• We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer's disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases. (lidsen.com)
• Also Alzheimer's disease can be mixed with arteriosclerotic small-vessel disease. (lidsen.com)
• Purpose: The influence of cerebral amyloid angiopathy (CAA) in Alzheimer's disease (AD) remains unexplored. (lidsen.com)

Vessel2

• Are neuropsychiatric symptoms a marker of small vessel disease progression in older adults? (ed.ac.uk)
• CBAs may not be a significant cause of ICH but are a manifestation of severe cerebral small vessel disease including both hypertensive arteriopathy and CAA. (nature.com)

Accidents1

• Cerebrovascular accidents (CVA) are one of the major causes of disability among human adults. (vin.com)

Biomarkers1

• The possible role of NETs and other markers of neutrophil activation as biomarkers of activity in RA and other immune-mediated diseases has also been studied.This article reviews the role of NETs in RA. (bvsalud.org)

Symptoms5

• This means the symptoms worsen over time and can appear suddenly after the cerebrovascular event or some time after. (medicalnewstoday.com)
• CADASIL can sometimes have other symptoms and be disguised as phenotypes atypical of this disease. (annaly-nevrologii.com)
• Research on the signs, symptoms, and pathogenesis of WNV disease has greatly intensified in the past 5 years. (cdc.gov)
• Unfortunately, because the symptoms of CFS are subjective and nonspecific, the disease is likely to be misdiagnosed. (ncf-net.org)
• Approximately 15% of patients follow a primary progressive or progressive relapsing course from disease onset, usually characterized by symptoms of progressive myelopathy (gait instability, spasticity, bladder symptoms) and cognitive impairment. (medscape.com)

Enfermedad2

• Enfermedad aterosclerótica intracraneal y pérdida dental severa en adultos mayores. (gob.ec)
• En el presente estudio se evaluó si la pérdida de dientes severa, utilizada como sustituto de enfermedad periodontal inflamatoria crónica, está asociada con EIAC en adultos mayores que viven en pueblos rurales. (gob.ec)

Clinical4

• OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches - including gene therapy, cell therapy, and epigenetic modulation - will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. (lidsen.com)
• With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm. (lidsen.com)
• The main principles of diagnosis of this disease characterized by clinical polymorphism are discussed. (annaly-nevrologii.com)
• At present, the diagnosis of CFS is made predominantly on clinical grounds, although serologic and immunologic correlates of the disease continue to be investigated. (ncf-net.org)

Hypertension1

• A history of vascular risk factors (hypertension, heart disease, diabetes and cigarette smoking) was obtained. (edu.au)

Systemic autoimmu1

• Research on the pathogenic mechanisms involved in systemic autoimmune diseases has largely focused on the involvement of the adaptive immune system with dysregulated responses of T and B cells. (bvsalud.org)

Brain3

• We evaluated the relationship between brain rhythmicity and both the cerebrovascular damage (CVD) and amygdalohippocampal complex (AHC) atrophy, as revealed by scalp electroencephalography (EEG) in a cohort of subjects with mild cognitive impairment (MCI). (hindawi.com)
• While previous studies have shown that hot flashes can be linked to signs of subclinical heart disease, such as changes in the blood vessels, as well as high blood pressure and elevated cholesterol levels, the current study examined the possible connection between hot flashes and brain health. (health-innovations.org)
• They also conducted MRI brain imaging on participants which detected white matter hyperintensities, these are bright spots on the scan that are thought to develop due to disease of the brain's small blood vessels. (health-innovations.org)

Chronic Disease1

• however, a variable but measurable amount of AD pathologic changes exist in most cognitively intact elderly individuals who undergo autopsy, indicating that AD is a chronic disease with latent and prodromal stages and suggesting that individuals may have varying abilities to compensate, either biologically or functionally, for the presence of AD. (medscape.com)

Secondary1

• Explanations of this concurrence includes simple coexistence at the time of the medical diagnosis, a reaction to the psychological stress of dealing with the disease, an effect resulting from the disease itself or occurring secondary to the medication used to treat the disorder. (pharmacology2000.com)

Cardiovascular4

• Cardiovascular screening and genetics in competitive athletes, disease gene discovery in cardiomyopathy and rare disease. (stanford.edu)
• Logistic regression models were fitted to assess the independent association between severe tooth loss and ICAD, after adjusting for demographics, cardiovascular risk factors and MRI evidence of cerebrovascular damage. (gob.ec)
• Se ajustaron modelos de regresión logística para evaluar la asociación independiente entre la pérdida de dientes y la EIAC, después de ajustar por variables tales como demografía, factores de riesgo cardiovascular y evidencia de MRI de daño cerebrovascular. (gob.ec)
• Introduction Diabetes increases the risk of cardiovascular disease. (docksci.com)

Progression2

• So far, from a neuropathological point of view, the progression of disease from MCI state to later stages seems to follow a linear course. (hindawi.com)
• Onset is usually in the fifth decade and disease progression occurs over several years. (uchicago.edu)

Congenital2

• Congenital Central Hypoventilation Syndrome, also known as haddad syndrome, is related to central hypoventilation syndrome, congenital, 1 and hirschsprung disease 1. (silexon.tech)
• Note: If you'd like to get a target analysis report for Congenital Central Hypoventilation Syndrome , or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Congenital Central Hypoventilation Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at [email protected] . (silexon.tech)

Supranuclear Palsy1

• Disease course and treatment patterns in progressive supranuclear palsy: A real-world study. (uchicago.edu)

Genetics1

• Illarioshkin S.N. [Genetics of cerebrovascular diseases]. (annaly-nevrologii.com)

Infectious2

• By definition, in patients with CFS there is no evidence of rheu-matologic, endocrinologic, infectious, malignant, or other chronic diseases, and no active psychiatric disease at the onset of the syndrome. (ncf-net.org)
• certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)

Involvement1

• Diagnostic criteria and classification of multiple sclerosis subtypes have evolved in recent decades, and, although successive versions have differed in emphasis, all have required dissemination of disease in space (requiring involvement of multiple areas of the CNS) and in time (requiring ongoing disease activity over time). (medscape.com)

Atrophy1

• These somewhat contradictory findings may be explained by the possibility that MCI subjects have different patterns of plastic organization during the disease and that the activation (or hypoactivation) of different cerebral areas is based on various degrees of hippocampal atrophy. (hindawi.com)