Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.
A form of panniculitis characterized by recurrent episodes of fever accompanied by the eruption of single or multiple erythematous subcutaneous nodules on the lower extremities. They normally resolve, but tend to leave depressions in the skin. The condition is most often seen in women, alone or in association with other disorders.
An erythematous eruption commonly associated with drug reactions or infection and characterized by inflammatory nodules that are usually tender, multiple, and bilateral. These nodules are located predominantly on the shins with less common occurrence on the thighs and forearms. They undergo characteristic color changes ending in temporary bruise-like areas. This condition usually subsides in 3-6 weeks without scarring or atrophy.
A characteristic symptom complex.
Study of stamps or postal markings. It usually refers to the design and commemorative aspects of the stamp.
Study of coins, tokens, medals, etc. However, it usually refers to medals pertaining to the history of medicine.
Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
The artery supplying nearly all the left half of the transverse colon, the whole of the descending colon, the sigmoid colon, and the greater part of the rectum. It is smaller than the superior mesenteric artery (MESENTERIC ARTERY, SUPERIOR) and arises from the aorta above its bifurcation into the common iliac arteries.
Eponyms in medicine are terms that are named after a person, typically the physician or scientist who first described the disease, condition, or procedure, such as Alzheimer's disease or Parkinson's disease.
Skin diseases affecting or involving the cutaneous blood vessels and generally manifested as inflammation, swelling, erythema, or necrosis in the affected area.
Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.
A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*51 allele family.
Semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine.
A condition characterized by the dilated tortuous veins of the SPERMATIC CORD with a marked left-sided predominance. Adverse effect on male fertility occurs when varicocele leads to an increased scrotal (and testicular) temperature and reduced testicular volume.
A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742)
The anteriorly located rigid section of the PALATE.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Inflammation of the lymph nodes.
Inflammation of the throat (PHARYNX).
A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842)

Autoantibodies to T cell costimulatory molecules in systemic autoimmune diseases. (1/725)

To determine whether antilymphocyte Abs to T cell costimulatory molecules are generated in patients with autoimmune diseases and, if they exist, to clarify the mechanism of their production and pathological roles, we investigated the presence of autoantibodies to CTLA-4 (CD152), CD28, B7-1 (CD80), and B7-2 (CD86) in serum samples obtained from patients with various autoimmune diseases and from normal subjects using recombinant fusion proteins. In ELISAs, anti-CD28, anti-B7-1, and anti-B7-2 Abs were rarely seen, whereas anti-CTLA-4 Abs were detected in 8.2% of the patients with systemic lupus erythematosus, 18.8% of those with rheumatoid arthritis, 3.1% of those with systemic sclerosis, 31.8% of those with Behcet's disease, 13.3% of those with Sjogren's syndrome, and 0% of healthy donors. This reactivity was confirmed by immunoblotting. More importantly, the purified anti-CTLA-4 Abs reacted with CTLA-4 expressed on P815 cells by flow cytometry. In addition, we found at least three epitopes on the CTLA-4 molecule. Furthermore, among the patients with Behcet's disease, uveitis was seen significantly less frequently in the anti-CTLA-4 Ab-positive patients. Taken collectively, these data indicate that anti-CTLA-4 autoantibodies are generated in systemic autoimmune diseases by an Ag-driven mechanism and may modulate the immune response in vivo by binding to CTLA-4 on T cells.  (+info)

The critical region for Behcet disease in the human major histocompatibility complex is reduced to a 46-kb segment centromeric of HLA-B, by association analysis using refined microsatellite mapping. (2/725)

The HLA-B51 allele is known to be associated with Behcet disease. Recently, we found a higher risk for Behcet disease in the MICA gene, 46 kb centromeric of HLA-B, by investigation of GCT repetitive polymorphism within exon 5 of MICA. The pathogenic gene causing Behcet disease, however, has remained uncertain. Here, eight polymorphic microsatellite markers, distributed over a 900-kb region surrounding the HLA-B locus, were subjected to association analysis for Behcet disease. Statistical studies of associated alleles detected on each microsatellite locus showed that the pathogenic gene for Behcet disease is most likely found within a 46-kb segment between the MICA and HLA-B genes. The results of this mapping study, and the results of an earlier study of ours, suggest that MICA is a strong candidate gene for the development of Behcet disease.  (+info)

Behcet's disease sera containing antiendothelial cell antibodies promote adhesion of T lymphocytes to cultured human dermal microvascular endothelial cells. (3/725)

Antiendothelial cell antibodies (AECA) have been detected in the sera of patients of autoimmune diseases showing vasculitis. Using IgM-ELISA, we found AECA in 42 (56%) of 75 sera samples from patients with Behcet's disease in a previous study. All of the 15 AECA-positive sera of Behcet's disease patients had an increased expression of the intercellular cell adhesion molecule-1 (ICAM-1), 93.3% of the sera induced the vascular cell adhesion molecule-1 (VCAM-1), and 100% of the serum induced the E-selectin molecule on human dermal microvascular endothelial cells (HDMEC). After stimulation of HDMEC with AECA-positive sera of Behcet's disease patients, the expression of ICAM-1 and VCAM-1 on HDMEC increased significantly at 4 hours, reaching a peak at 16 hours. Expression of E-selectin was induced at 1 hour after stimulation with a peak at 4 hours and it decreased thereafter. Adherence of T lymphocytes to HDMEC increased significantly after stimulation with AECA-positive sera from Behcet's disease patients. Also, the adherence of T lymphocytes to HDMEC increased at 4 hours and returned to its normal level at 48 hours. These results show that AECA-positive sera of Behcet's disease patients are capable of activating HDMEC to promote the adherence of T lymphocytes to increase the expression of ICAM-1, VCAM-1, and E-selectin on the cell surfaces. The whole process may play an important role in the pathogenesis of vasculitis in Behcet's disease.  (+info)

Childhood Behcet's disease: clinical features and comparison with adult-onset disease. (4/725)

OBJECTIVE: To study the clinical spectrum of Behcet's disease (BD) in childhood, in comparison to adult-onset disease. METHODS: Nineteen children, who fulfilled disease criteria up to the age of 16 yr, were studied. The results were compared to those of 34 adult patients with BD. An activity index and severity score were calculated for both study groups. RESULTS: The mean age of disease onset was 6.9+/-3.9 yr, similar ages of onset were found in males and females. The clinical spectrum of childhood BD resembled that of adult disease; however, the prevalence of certain manifestations was different between children and adults. Children with BD had significantly less genital ulcers, less vascular thromboses and more non-specific gastrointestinal symptoms, as well as central nervous system involvement and arthralgia. A relatively high prevalence of uveitis was found in childhood BD. The activity index and severity score were significantly lower in children than in adults. CONCLUSION: Our results point to a similar systemic expression of BD in children and adults; however, the disease seems to run a less severe course in children.  (+info)

Anti-Sa antibody in Chinese rheumatoid arthritis. (5/725)

OBJECTIVE: To test anti-Sa antibody in different autoimmune connective tissue diseases and analyze the relationship between Sa antibody and clinical manifestations and laboratory tests in rheumatoid arthritis. METHOD: Sa antigen was extracted from human placenta. Anti-Sa antibody was tested in 40 normal people and 478 connective tissue disease (CTD) patients using Western Blotting (WB). RESULTS: Sa antigen was a protein with molecular weights of 50 kD and 55 kD. Anti-Sa antibody was positive in 31.9% (61/191) rheumatoid arthritis (RA), 3.0% (2/67) Sjogren's syndrome (SS), 4.3% (2/46) systemic lupus erythmatosus (SLE) and 0% (0/66) Behcet's disease, 0% (0/60) polymyositis/dermatomyositis (PM/DM), 0% (0/66) other CTD and 0% (0/40) normal controls. Anti-Sa antibody was different from other auto-antibodies in RA. In rheumatoid arthritis its sensitivity, specificity, positive prediction rate, negative prediction rate were 31.9%, 98.6%, 93.8% and 68.5% respectively. Anti-Sa antibody positive patients were significantly different from anti-Sa antibody negative patients in moming stiffness, ESR, ANA and X-ray grade. CONCLUSION: Anti-Sa antibody was a new auto-antibody for the diagnosis of RA. Anti-Sa antibody positive patients seem to have more serious inflammation and more advanced disease process.  (+info)

Oligoclonal T cell expansions in patients with Behcet's disease. (6/725)

Behcet's disease (BD) is a multisystem disorder with oral and genital ulcers, mucocutaneous, ocular, joint, vascular and central nervous system involvement. In this study, the peripheral T cell repertoire was analysed in patients with BD with MoAbs against T cell receptor (TCR) Vbeta gene products in CD4+ and CD8+ T cell compartments, and these were compared with rheumatoid arthritis (RA) patients and healthy controls (HC). In the CD4+ T cell compartment, oligoclonal TCR Vbeta expression was observed in 56% of BD (10/18), 71% of RA (5/7) patients and 21% (3/14) of HC. In the CD8+ T cell group 50% of BD (9/18), 57% of RA patients and 28% of HC (4/14) had an oligoclonal TCR repertoire. An increase of TCR Vbeta5.1 subset was observed in five BD patients among CD8+ T cells. Other elevations of TCR Vbeta subsets were heterogeneously distributed with one to three different Vbeta subsets. Our results suggest an antigen-driven oligoclonal increase of T cells in BD. There was no overall increase in any Vbeta group to suggest a superantigen effect. Analysis of the responsible antigens causing the increase in T cell subsets may give insights into the aetiopathogenesis of BD and immunomodulation of these T cells may lead to new treatments.  (+info)

Neuro-Behcet's disease presenting with isolated unilateral lateral rectus muscle palsy. (7/725)

The authors present the clinical findings of a 30-year-old female and a 29-year-old male who both had isolated unilateral lateral rectus muscle palsy in neuro-Behcet's disease. The clinical feature related to isolated abduscens nerve palsy was identified by CT, systemic assessment and extraocular examination. These patients' constellation of findings appear to be unique: it does not follow any previously reported pattern of ocular manifestations of neuro-Behcet's disease.  (+info)

Association of MICA gene and HLA-B*5101 with Behcet's disease in Greece. (8/725)

PURPOSE: Behcet's disease (BD) is known to be associated with HLA-B51 in many different ethnic groups. Recently MICA, a member of a novel family of the human major histocompatibility complex (MHC) class I genes termed MIC (MHC class I chain-related genes), was identified near the HLA-B gene, and a triplet repeat microsatellite polymorphism was found in the transmembrane (TM) region. Because a strong association with BD of one particular MICA-TM allele, A6, was shown in a Japanese population, the present study was conducted to investigate microsatellite polymorphism in Greek patients with BD to know whether this association is generally observed in BD occurring in other populations. METHODS: Thirty-eight Greek patients with BD and 40 ethnically matched control subjects were examined for MICA microsatellite polymorphism using polymerase chain reaction (PCR) and subsequent automated fragment detection by fluorescent-based technology. RESULTS: Similar to the Japanese patients with BD, the phenotype frequency of the MICA-TM A6 allele was significantly increased in the Greek patients with BD (50.0% in control subjects versus 86.8% in BD cases), with an odds ratio (OR) of 6.60 (P = 0.0012). The MICA-A6 allele was found in a high frequency both in males and females (weighted OR = 6.68; P = 0.0017). No association was found between the A6 allele and several disease features. A strong association exists between the MICA-TM A6 allele and the B*5101 allele in both the control subjects and patients with BD (weighted OR = 44.39; P = 0.0000023). CONCLUSIONS: This study revealed in Greek patients a strong association of BD with a particular MICA-TM allele, MICA-A6, providing insight into the molecular mechanism underlying the development of BD.  (+info)

Behçet syndrome is a rare inflammatory disease that can cause symptoms in various parts of the body. It's characterized by recurrent mouth sores (aphthous ulcers), genital sores, and inflammation of the eyes (uveitis). The condition may also cause skin lesions, joint pain and swelling, and inflammation of the digestive tract, brain, or spinal cord.

The exact cause of Behçet syndrome is not known, but it's thought to be an autoimmune disorder, in which the body's immune system mistakenly attacks its own healthy cells and tissues. The condition tends to affect men more often than women and typically develops during a person's 20s or 30s.

There is no cure for Behçet syndrome, but treatments can help manage symptoms and prevent complications. Treatment options may include medications such as corticosteroids, immunosuppressants, and biologics to reduce inflammation, as well as pain relievers and other supportive therapies.

Nodular nonsuppurative panniculitis is a rare inflammatory condition that affects the subcutaneous fat tissue. The term "nonsuppurative" indicates that it does not involve pus formation or suppuration, unlike some other forms of panniculitis.

In nodular nonsuppurative panniculitis, multiple, firm, and occasionally tender nodules develop in the subcutaneous fat layer, usually on the lower extremities but can also occur on the abdomen, arms, and trunk. These nodules may vary in size from a few millimeters to several centimeters.

The etiology of nodular nonsuppurative panniculitis is not well understood, although it has been associated with various conditions such as autoimmune disorders (e.g., lupus erythematosus, rheumatoid arthritis), infections (e.g., hepatitis C, HIV), medications (e.g., bromocriptine, interferon), and malignancies (e.g., lymphoma).

Histologically, the condition is characterized by a lobular inflammatory infiltrate predominantly composed of lymphocytes, histiocytes, and occasionally plasma cells, with sparing of septa. The overlying skin may appear normal or show mild changes such as erythema or induration.

Treatment for nodular nonsuppurative panniculitis depends on the underlying cause. If an associated condition or medication is identified, addressing it may lead to resolution of the panniculitis. In cases where no specific cause is found, various treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, immunosuppressive agents, and antimalarials have been used with varying success rates.

Erythema nodosum is a type of inflammation that occurs in the fatty layer of the skin, causing painful, red or purple bumps (nodules) to form. It is a type of panniculitis, which refers to any condition that causes inflammation of the fatty layer of tissue beneath the skin.

Erythema nodosum is often associated with a variety of underlying conditions, such as infections (e.g., streptococcus, tuberculosis), medications (e.g., sulfa drugs, oral contraceptives), inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis), and pregnancy.

The bumps associated with erythema nodosum typically appear on the shins, ankles, knees, or other areas of the legs, although they can also occur on the arms, hands, or face. The bumps may be tender to the touch, warm, and swollen, and they may cause pain or discomfort when walking or standing for prolonged periods.

In most cases, erythema nodosum resolves on its own within a few weeks to several months, although symptoms can be managed with medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. Treating the underlying condition is also important for resolving erythema nodosum and preventing recurrences.

A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.

For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.

It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.

Philately is not a medical term. It is actually a term used to describe the hobby or study of stamps, postmarks, and postal history. The word comes from the Greek "philos" meaning "lover" and "ateleia" meaning "exemption from taxes," which described the early stamps that were used to indicate payment of taxes on mail. It's a bit surprising that you asked for a medical definition of this term, as it is not related to medicine in any way.

I'm sorry for any confusion, but "numismatics" is not a term typically used in medical definitions. Numismatics is the study or collection of coins, tokens, and currency, including their history, design, and cultural significance. It is not a medical concept or diagnosis. If you have any questions related to medical terminology or health concerns, I would be happy to try to help with those instead!

Epididymitis is defined as the inflammation of the epididymis, a curved tube-like structure located at the back of the testicle that stores and transports sperm. The inflammation can result from infection, trauma, or other causes, and may cause symptoms such as pain, swelling, and tenderness in the scrotum. In some cases, epididymitis may also be associated with urinary tract infections, sexually transmitted infections, or other medical conditions. Treatment typically involves antibiotics to treat any underlying infection, as well as pain relief measures and supportive care to help reduce symptoms and promote healing.

The Inferior Mesenteric Artery (IMA) is a major artery that supplies blood to the distal portion of the large intestine, including the descending colon, sigmoid colon, and rectum. It originates from the abdominal aorta, typically at the level of the third lumbar vertebra (L3), and descends anteriorly to the left psoas major muscle before crossing the iliac crest and entering the pelvis.

Once in the pelvis, the IMA divides into several branches, including the left colic artery, which supplies the descending colon; the sigmoidal branches, which supply the sigmoid colon; and the superior rectal artery, which supplies the upper part of the rectum. The inferior mesenteric artery plays a crucial role in maintaining blood flow to the distal gut and is often evaluated during surgical procedures involving the abdomen or pelvis.

An eponym is a name derived from a person, usually the person who first described a medical condition or invention. In medicine, eponyms are often used to describe specific signs, symptoms, conditions, or diagnostic tests. For example, Alzheimer's disease is named after Alois Alzheimer, who first described the condition in 1906. Similarly, Parkinson's disease is named after James Parkinson, who first described it in 1817.

Eponyms can be helpful in medical communication because they provide a quick and easy way to refer to specific medical concepts. However, they can also be confusing or misleading, especially when the eponym's origin is not well-known or when different eponyms are used for the same concept. Therefore, it is essential to use eponyms appropriately and understand their underlying medical concepts.

Vascular skin diseases are a group of medical conditions that affect the blood vessels in the skin. These disorders can be caused by problems with the structure or function of the blood vessels, which can lead to various symptoms such as redness, discoloration, pain, itching, and ulcerations. Some examples of vascular skin diseases include:

1. Rosacea: a chronic skin condition that causes redness, flushing, and visible blood vessels in the face.
2. Eczema: a group of inflammatory skin conditions that can cause redness, itching, and dryness. Some types of eczema, such as varicose eczema, are associated with problems with the veins.
3. Psoriasis: an autoimmune condition that causes red, scaly patches on the skin. Some people with psoriasis may also develop psoriatic arthritis, which can affect the blood vessels in the skin and joints.
4. Vasculitis: a group of conditions that cause inflammation of the blood vessels. This can lead to symptoms such as redness, pain, and ulcerations.
5. Livedo reticularis: a condition that causes a net-like pattern of discoloration on the skin, usually on the legs. It is caused by abnormalities in the small blood vessels.
6. Henoch-Schönlein purpura: a rare condition that causes inflammation of the small blood vessels, leading to purple spots on the skin and joint pain.
7. Raynaud's phenomenon: a condition that affects the blood vessels in the fingers and toes, causing them to become narrow and restrict blood flow in response to cold temperatures or stress.

Treatment for vascular skin diseases depends on the specific condition and its severity. It may include medications, lifestyle changes, and in some cases, surgery.

An aneurysm is a localized, balloon-like bulge in the wall of a blood vessel. It occurs when the pressure inside the vessel causes a weakened area to swell and become enlarged. Aneurysms can develop in any blood vessel, but they are most common in arteries at the base of the brain (cerebral aneurysm) and the main artery carrying blood from the heart to the rest of the body (aortic aneurysm).

Aneurysms can be classified as saccular or fusiform, depending on their shape. A saccular aneurysm is a round or oval bulge that projects from the side of a blood vessel, while a fusiform aneurysm is a dilated segment of a blood vessel that is uniform in width and involves all three layers of the arterial wall.

The size and location of an aneurysm can affect its risk of rupture. Generally, larger aneurysms are more likely to rupture than smaller ones. Aneurysms located in areas with high blood pressure or where the vessel branches are also at higher risk of rupture.

Ruptured aneurysms can cause life-threatening bleeding and require immediate medical attention. Symptoms of a ruptured aneurysm may include sudden severe headache, neck stiffness, nausea, vomiting, blurred vision, or loss of consciousness. Unruptured aneurysms may not cause any symptoms and are often discovered during routine imaging tests for other conditions.

Treatment options for aneurysms depend on their size, location, and risk of rupture. Small, unruptured aneurysms may be monitored with regular imaging tests to check for growth or changes. Larger or symptomatic aneurysms may require surgical intervention, such as clipping or coiling, to prevent rupture and reduce the risk of complications.

HLA-B51 is a specific type of human leukocyte antigen (HLA) Class I histocompatibility antigen. Histocompatibility antigens are proteins found on the surface of cells that help the immune system recognize and distinguish between "self" and "non-self."

The HLA-B51 antigen is encoded by the HLA-B gene, which is located on chromosome 6. This particular antigen has been associated with a higher risk of developing certain autoimmune diseases, such as Behçet's disease, a rare inflammatory disorder that causes symptoms such as mouth sores, genital sores, eye inflammation, and skin lesions.

It is important to note that while the presence of HLA-B51 antigen may increase the risk of developing Behçet's disease, it does not necessarily mean that an individual will definitely develop the condition. Other genetic and environmental factors are also believed to play a role in its development.

Penicillin G Benzathine is a type of antibiotic that is used to treat various bacterial infections. According to the International Journal of Antimicrobial Agents, Penicillin G Benzathine is a "water-soluble salt of penicillin G, which has a very high degree of stability and provides prolonged low-level serum concentrations after intramuscular injection."

It is often used to treat infections caused by streptococci and treponema pallidum, the bacterium that causes syphilis. Penicillin G Benzathine works by interfering with the ability of these bacteria to form a cell wall, which is essential for their survival. Without a functional cell wall, the bacteria are unable to grow and multiply, and are eventually destroyed by the body's immune system.

Penicillin G Benzathine is typically administered via intramuscular injection, and its prolonged release allows for less frequent dosing compared to other forms of penicillin. However, it may not be suitable for all patients, particularly those with a history of allergic reactions to penicillin or other antibiotics. As with any medication, Penicillin G Benzathine should only be used under the supervision of a healthcare provider.

A varicocele is defined as an abnormal dilation and tortuosity (twisting or coiling) of the pampiniform plexus, which is a network of veins that surrounds the spermatic cord in the scrotum. This condition is most commonly found on the left side, and it's more prevalent in men of reproductive age.

The dilation of these veins can cause a decrease in the temperature around the testicle, leading to impaired sperm production, reduced sperm quality, and, in some cases, pain or discomfort. Varicoceles are often asymptomatic but may present as a scrotal mass, discomfort, or infertility issues. In severe cases or when accompanied by symptoms, treatment options include surgical ligation (tying off) or embolization of the affected veins to improve testicular function and alleviate symptoms.

Down syndrome is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is characterized by intellectual and developmental disabilities, distinctive facial features, and sometimes physical growth delays and health problems. The condition affects approximately one in every 700 babies born in the United States.

Individuals with Down syndrome have varying degrees of cognitive impairment, ranging from mild to moderate or severe. They may also have delayed development, including late walking and talking, and may require additional support and education services throughout their lives.

People with Down syndrome are at increased risk for certain health conditions, such as congenital heart defects, respiratory infections, hearing loss, vision problems, gastrointestinal issues, and thyroid disorders. However, many individuals with Down syndrome live healthy and fulfilling lives with appropriate medical care and support.

The condition is named after John Langdon Down, an English physician who first described the syndrome in 1866.

Metabolic syndrome, also known as Syndrome X, is a cluster of conditions that increase the risk of heart disease, stroke, and diabetes. It is not a single disease but a group of risk factors that often co-occur. According to the American Heart Association and the National Heart, Lung, and Blood Institute, a person has metabolic syndrome if they have any three of the following five conditions:

1. Abdominal obesity (waist circumference of 40 inches or more in men, and 35 inches or more in women)
2. Triglyceride level of 150 milligrams per deciliter of blood (mg/dL) or greater
3. HDL cholesterol level of less than 40 mg/dL in men or less than 50 mg/dL in women
4. Systolic blood pressure of 130 millimeters of mercury (mmHg) or greater, or diastolic blood pressure of 85 mmHg or greater
5. Fasting glucose level of 100 mg/dL or greater

Metabolic syndrome is thought to be caused by a combination of genetic and lifestyle factors, such as physical inactivity and a diet high in refined carbohydrates and unhealthy fats. Treatment typically involves making lifestyle changes, such as eating a healthy diet, getting regular exercise, and losing weight if necessary. In some cases, medication may also be needed to manage individual components of the syndrome, such as high blood pressure or high cholesterol.

Aphthous stomatitis, also known simply as canker sores, is a medical condition that involves the development of small, painful ulcers in the mouth. These ulcers typically appear on the inside of the lips or cheeks, under the tongue, or on the gums. They are usually round or oval with a white or yellow center and a red border.

Aphthous stomatitis is not contagious and is thought to be caused by a variety of factors, including stress, hormonal changes, nutritional deficiencies, and injury to the mouth. The ulcers typically heal on their own within one to two weeks, although larger or more severe sores may take longer to heal.

Treatment for aphthous stomatitis is generally focused on relieving symptoms, as there is no cure for the condition. This may include using over-the-counter mouth rinses or topical gels to numb the area and reduce pain, as well as avoiding spicy, acidic, or hard foods that can irritate the ulcers. In some cases, prescription medications may be necessary to help manage more severe or persistent cases of aphthous stomatitis.

The hard palate is the anterior, bony part of the roof of the mouth, forming a vertical partition between the oral and nasal cavities. It is composed of the maxilla and palatine bones, and provides attachment for the muscles of the soft palate, which functions in swallowing, speaking, and breathing. The hard palate also contains taste buds that contribute to our ability to taste food.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Lymphadenitis is a medical term that refers to the inflammation of one or more lymph nodes, which are small, bean-shaped glands that are part of the body's immune system. Lymph nodes contain white blood cells called lymphocytes, which help fight infection and disease.

Lymphadenitis can occur as a result of an infection in the area near the affected lymph node or as a result of a systemic infection that has spread through the bloodstream. The inflammation causes the lymph node to become swollen, tender, and sometimes painful to the touch.

The symptoms of lymphadenitis may include fever, fatigue, and redness or warmth in the area around the affected lymph node. In some cases, the overlying skin may also appear red and inflamed. Lymphadenitis can occur in any part of the body where there are lymph nodes, including the neck, armpits, groin, and abdomen.

The underlying cause of lymphadenitis must be diagnosed and treated promptly to prevent complications such as the spread of infection or the formation of an abscess. Treatment may include antibiotics, pain relievers, and warm compresses to help reduce swelling and discomfort.

Pharyngitis is the medical term for inflammation of the pharynx, which is the back portion of the throat. This condition is often characterized by symptoms such as sore throat, difficulty swallowing, and scratchiness in the throat. Pharyngitis can be caused by a variety of factors, including viral infections (such as the common cold), bacterial infections (such as strep throat), and irritants (such as smoke or chemical fumes). Treatment for pharyngitis depends on the underlying cause of the condition, but may include medications to relieve symptoms or antibiotics to treat a bacterial infection.

An oral ulcer is a defect or break in the continuity of the epithelium, the tissue that lines the inner surface of the mouth, leading to an inflamed, painful, and sometimes bleeding lesion. They can be classified as primary (e.g., aphthous ulcers, traumatic ulcers) or secondary (e.g., those caused by infections, underlying systemic conditions, or reactions to medications). Oral ulcers may cause discomfort, impacting speech and food consumption, and their presence might indicate an underlying medical issue that requires further evaluation.

Dalvi SR, Yildirim R, Yazici Y (December 2012). "Behcet's Syndrome". Drugs. 72 (17): 2223-41. doi:10.2165/11641370-000000000- ... MAGIC syndrome is a possible variant of Behçet's disease, and is associated with aphthous-like ulceration. The name stands for ... Synonyms for major RAS include Sutton's ulcers (named after Richard Lightburn Sutton), Sutton's disease, Sutton's syndrome and ... "mouth and genital ulcers with inflamed cartilage" (relapsing polychondritis). PFAPA syndrome is a rare condition that tends to ...
"Behcet's Syndrome: MedlinePlus". nih.gov. Archived from the original on 4 July 2016. Retrieved 19 September 2016. Piga, M; ... "Pharmacotherapy for Behcet's syndrome". Cochrane Database of Systematic Reviews. 1998 (2): CD001084. doi:10.1002/14651858. ... "A double-blind trial of colchicine in Behcet's syndrome". Arthritis Rheum. 44 (11): 2686-92. doi:10.1002/1529-0131(200111)44:11 ... "Thalidomide in the treatment of the mucocutaneous lesions of the Behcet syndrome. A randomized, double-blind, placebo- ...
Curth, Helen Ollendorff (August 1946). "Recurrent genito-oral aphthosis and uveitis with hypopyon (Behcet's syndrome)". ... Buschke-Ollendorff syndrome, Marfan's syndrome and osteogenesis imperfecta". In Hoeger, Peter H.; Kinsler, Veronica; Yan, ... Paraneoplastic syndromes in the skin". In Hertl, Michael (ed.). Autoimmune Diseases of the Skin: Pathogenesis, Diagnosis, ... She is named in two rare inherited skin diseases, the Buschke-Ollendorff syndrome and Ichthyosis Hystrix, Curth-Macklin Type. A ...
"A double-blind trial of depot corticosteroids in Behcet's syndrome". Rheumatology. 45 (3): 348-52. doi:10.1093/rheumatology/ ... A chest X-ray should be performed to rule out pulmonary diseases, in particular sarcoidosis and Löfgren syndrome. Erythema ... "A double-blind trial of colchicine in Behçet's syndrome". Arthritis & Rheumatism. 44 (11): 2686-92. doi:10.1002/1529-0131( ...
Mor, F; Weinberger, A; Cohen, IR (2002). "Identification of alpha-tropomyosin as a target self-antigen in Behcet's syndrome". ... tropomyosin antibodies have also been reported in acute rheumatic fever and the inflammatory disorder Behcet's syndrome. In ...
Behcet's syndrome commonly presents in the 30-40 age range and is more common in the Middle East and Asia. There is a familial ... Behcet's syndrome is a chronic systemic vasculitis infection that is defined by recurrent oral and genital aphthous ulcers but ... a genital ulcer may also be the result of non-infectious causes such as Behcet's syndrome, lupus, or psoriasis. Since it is ... component to Behcet's syndrome since it has associations with the HLA-B51 gene. Causes of drug induced genital ulcers take the ...
Behcet syndrome, antiphospholipid antibody syndrome or blunt trauma to the back or abdomen. Treatment of RVT mainly focuses on ... Behcet syndrome, antiphospholipid antibody syndrome or blunt trauma to the back or abdomen. Damage to the endothelial tissue of ... The incidence of RVT in people with Nephrotic syndrome ranges from 5% to 65%. Nephrotic syndrome is caused by membranous ... newly born infants with blood clotting abnormalities or dehydration and adults with nephrotic syndrome. Nephrotic syndrome, a ...
... and immune-related inflammations such as Behcet syndrome or Vogt-Koyanagi-Harada disease causes panuveitis. Infections from a ...
Behcet's Syndrome, pemphigus vulgaris, herpes simplex, histoplasmosis, and reactive arthritis. A heart attack is a blood vessel ... Arthralgia and Arthritis and Carpal Tunnel Syndrome. Arthralgia and Carpal Tunnel Syndrome both have an impact on a patients' ... A CD4 count less than 200 is a diagnosis of Acquired Immunodeficiency Syndrome (AIDS). Oral manifestations of human ... can experience burning mouth syndrome and candidal infections as well as experiencing altered taste sensation, altered tooth ...
... intestinal tuberculosis and Behcet's syndrome". The American Journal of the Medical Sciences. 346 (6): 467-72. doi:10.1097/MAJ. ... chronic fatigue syndrome, low plasma protein (due to liver or kidney disease) and congestive heart failure. Although increases ... "Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome". Blood. 132 (Suppl 1): 4874. doi:10.1182/blood ...
... intestinal tuberculosis and Behcet's syndrome". The American Journal of the Medical Sciences. 346 (6): 467-472. doi:10.1097/MAJ ... Elevated levels of CRP appear to be associated with common comorbidities including cardiovascular disease, metabolic syndrome, ...
Sjögren syndrome, myasthenia gravis, systemic vasculitis, Behcet-like syndrome, dermatomyositis, granulomatosis with ... Wiskott-Aldrich syndrome, immunodeficiency with short-limbed dwarfism, immunodeficiency with thymoma, purine nucleoside ... chronic idiopathic neutrophilia Pelger-Huët anomaly Down syndrome Leukocyte adhesion deficiency Familial cold urticaria ...
Irritable bowel syndrome, migraines, osteoarthritis, Ehlers-Danlos syndrome, Neuro-Behcet's autoimmune disease, neuropathy, ... polycystic kidney disease, and superior canal dehiscence syndrome. When recreational marijuana becomes legal in January 2020, ...
Glioblastoma multiforme Prostate cancer Melanoma Colorectal cancer Crohn's disease Rheumatoid arthritis Behcet's syndrome ... Thalidomide can cause liver damage and severe skin reactions like Stevens-Johnson syndrome. It tends to make people sleepy, ... As it kills cancer cells, it can cause tumor lysis syndrome. Thalidomide can prevent menstruation. In addition, very common ( ... Severe side effects include tumor lysis syndrome, blood clots, and peripheral neuropathy. Use of thalidomide in pregnancy can ...
Behcet's syndrome - It is an inflammatory disorder in which the presenting symptoms are recurrent aphthous ulcers, and severe ... Stevens-Johnson syndrome: Stevens-Johnson syndrome is characterized by early symptoms of malaise and fever, and shortly after ...
... unspecified 135 Sarcoidosis 136 Other and unspecified infectious and parasitic diseases 136.0 Ainhum 136.1 Behcet's syndrome ...
Becker's nevus Beemer-Ertbruggen syndrome Beemer-Langer syndrome Behcet syndrome Behr syndrome Behrens-Baumann-Dust syndrome ... syndrome Bazopoulou-Kyrkanidou syndrome B-cell lymphomas Bd syndrome Beals syndrome Beardwell syndrome Bébé-Collodion syndrome ... sclerosis Bamforth syndrome BANF acoustic neurinoma Bangstad syndrome Banki syndrome Bannayan-Zonana syndrome Banti's syndrome ... syndrome Bonneman-Meinecke-Reich syndrome Bonnemann-Meinecke syndrome Bonnevie-Ullrich-Turner syndrome Book syndrome Boomerang ...
Post kala azar dermal leishmaniasis Eruptive xanthomas A similar response occurs in pyoderma gangrenosum and Behcet's syndrome ...
... behcet syndrome MeSH C11.941.879.780.880.400 - iridocyclitis MeSH C11.941.879.780.880.448 - iritis MeSH C11.941.879.780.900 - ... horner syndrome MeSH C11.710.570 - mydriasis MeSH C11.710.800 - tonic pupil MeSH C11.710.800.180 - aide syndrome MeSH C11.744. ... Hermansky-Pudlak syndrome MeSH C11.270.060 - aniridia MeSH C11.270.060.950 - WAGR syndrome MeSH C11.270.142 - choroideremia ... dry eye syndromes MeSH C11.496.260.394 - keratoconjunctivitis sicca MeSH C11.496.260.719 - Sjögren syndrome MeSH C11.496. ...
... syndrome, Buerger's, Behcet's, and Kawasaki disease. Various imaging techniques may be used to diagnose and monitor disease ... Similar symptoms may be caused by a number of other conditions, such as Ehlers-Danlos syndrome and Marfan syndrome (both ...
... syndrome Beare-Stevenson cutis gyrata syndrome Beckwith-Wiedemann syndrome Behcet's syndrome Behr syndrome Benedikt syndrome ... syndrome Wende-Bauckus syndrome Werner syndrome Wernicke-Korsakoff syndrome West syndrome Westerhof syndrome Wet lung syndrome ... syndrome Shone's syndrome Short anagen syndrome Short bowel syndrome short limb syndrome Short man syndrome Short QT syndrome ... syndrome Radial tunnel syndrome Rage syndrome Raghib syndrome Raine syndrome Ramos-Arroyo syndrome Ramsay Hunt syndrome type 1 ...
Acute disseminated encephalomyelitis (ADEM) Antiphospholipid antibody syndrome (APS or APLS) Behcet syndrome Chronic ... disease in infants and neonates Guillain-Barré syndrome HELLP syndrome HIV-related neuropathy Hyperviscosity syndromes: ... Miller Fisher syndrome Multiple sclerosis Myasthenia gravis Neuromyelitis optica Opsoclonus myoclonus syndrome PANDAS syndrome ... such as Goodpasture's syndrome, Guillain-Barré syndrome, lupus, myasthenia gravis, and thrombotic thrombocytopenic purpura. ...
Behcet syndrome MeSH C14.907.940.110 - Churg-Strauss syndrome MeSH C14.907.940.560 - mucocutaneous lymph node syndrome MeSH ... long QT syndrome MeSH C14.280.067.565.070 - Andersen syndrome MeSH C14.280.067.565.440 - Jervell and Lange-Nielsen syndrome ... CREST syndrome MeSH C14.907.790.100 - anterior spinal artery syndrome MeSH C14.907.790.550 - spinal cord ischemia MeSH C14.907. ... leopard syndrome MeSH C14.240.400.701 - levocardia MeSH C14.240.400.725 - Marfan syndrome MeSH C14.240.400.849 - tetralogy of ...
Behcet's, other retinal vasculitides, Neoplastic: intraocular lymphoma, leukemia, metastasis. If left untreated, PORN syndrome ... The syndrome, PORN, falls under the umbrella of necrotizing herpetic retinopathy, along with Acute retinal necrosis. Although ... Progressive outer retinal necrosis (PORN) syndrome is a form of chorioretinitis, an infection in the retina, the back of the ... Austin, RB (December 2000). "Progressive outer retinal necrosis syndrome: a comprehensive review of its clinical presentation, ...
"Behcet Disease: Overview - eMedicine Dermatology". Retrieved 2009-03-28. Petruzzelli GJ, Hirsch BE (August 1991). "Bell's palsy ... Kwan ES, Wolpert SM, Hedges TR, Laucella M (February 1988). "Tolosa-Hunt syndrome revisited: not necessarily a diagnosis of ... Maltsman-Tseikhin A, Moricca P, Niv D (June 2007). "Burning mouth syndrome: will better understanding yield better management ... Other examples include: Adult-onset Still's disease Behçet's disease Bell's palsy Burning mouth syndrome Chronic recurrent ...
April 2015). "Behçet's syndrome patients exhibit specific microbiome signature". Autoimmunity Reviews. 14 (4): 269-276. doi: ... 4 August 2018). "A metagenomic study of the gut microbiome in Behcet's disease". Microbiome. 6 (1): 135. doi:10.1186/s40168-018 ... Gibson, Peter R.; Varney, Jane; Malakar, Sreepurna; Muir, Jane G. (1 May 2015). "Food components and irritable bowel syndrome ...
Sjögren's syndrome (SS) and immune-related Congenital heart block. Ben-Chetrit detected a new antigen (52 KD) component of the ... He also participated in the NIH study which discovered the association of a SNP in the gene encoding IL-10 with Behcet's ... "Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes". New England Journal of Medicine. 378 (20): 1908- ...
Increasing rates of obesity and metabolic syndrome play a key role in the increased prevalence of chronic hypertension and ... Jadaon, J.; Shushan, A.; Ezra, Y.; Sela, H. Y.; Ozcan, C.; Rojansky, N. (2005). "Behcet's disease and pregnancy". Acta ... especially primary pulmonary hypertension and Eisenmenger's syndrome Kidney disorders Mental health. Depression has been linked ... Journal of Acquired Immune Deficiency Syndromes. 23 (3): 246-254. doi:10.1097/00042560-200003010-00006. PMID 10839660. S2CID ...
doi:10.1016/b978-0-12-385157-4.00848-4. ISBN 978-0-12-385158-1. Behcet A (2014-03-25). "The Source-Synthesis- History and Use ... "A short review of drug-food interactions of medicines treating overactive bladder syndrome". International Journal of Clinical ...
Immunosuppression BK virus Behcet's Disease Discovery and development of mTOR inhibitors Treatment methods for preventing organ ... In the first few administrations this binding non-specifically activates T-cells, leading to a serious syndrome 30 to 60 ... It is used in the treatment of autoimmune diseases (for example rheumatoid arthritis or Behcet's Disease) and in ... Behcet's Disease, pemphigus, ankylosing spondylitis, and ulcerative colitis). Treat some other non-autoimmune inflammatory ...
The Behcets Syndrome International Study Group Criteria calculator is created by QxMD. ... The Behcets Syndrome International Study Group Criteria calculator is created by QxMD. ... Behcets disease is an uncommon inflammatory disease for which there are several proposed diagnostic criteria. At the time of ... Behcets disease is an uncommon inflammatory disease for which there are several proposed diagnostic criteria. At the time of ...
... be it Behcets Syndrome, Crohns, or Celiac disease. ... Behcets Syndrome. *Drug induced (Fosamax, beta-blockers, ... For instance, Behcets disease and gastrointestinal reflux disease are both linked with canker sores. So, if you get ulcers on ...
Hulusi Behcet (1889-1948) recognized and reported in 1937 symptoms of Behcets syndrome. ... Morbus Behcet or Silk Road disease is the other name for Behcet Syndrome or disease. Month of May is Behcets Awareness month ... Behcets Syndrome Diagnosis. In the absence of a single test to diagnose Behcets syndrome, doctors look out for symptoms. ... Behcets Syndrome Treatment. There is no cure for Behcets syndrome. The treatment is aimed at alleviating the symptoms, ...
Copy For Citation Hatemi G., Melikoglu M., Tunc R., Korkmaz C., Ozturk B. T., Mat C., ...More NEW ENGLAND JOURNAL OF MEDICINE, vol.372, no.16, pp.1510-1518, 2015 (SCI-Expanded) ...
Hippocrates may have described Behçet disease in the fifth century BCE; however, the first description of the syndrome was ... Clinical and Ultrasonographic Evaluation of Lower-extremity Vein Thrombosis in Behcet Syndrome: An Observational Study. ... encoded search term (Behcet Disease) and Behcet Disease What to Read Next on Medscape ... Apremilast for Behçets syndrome--a phase 2, placebo-controlled study. N Engl J Med. 2015 Apr 16. 372 (16):1510-8. [QxMD ...
Behcets syndrome. March 15, 2023. General paediatrics, Genetics, Immunologyadmin Recurrent fever and aphthous stomatitis, ...
The syndrome carries the name of the Turkish dermatologist Hulusi Behçet, who, in 1937, described a syndrome of recurrent ... Behçet syndrome is a multisystem disease of unknown etiology probably first described by Hippocrates in the 5th century. ... encoded search term (Behcet Syndrome) and Behcet Syndrome What to Read Next on Medscape ... Genetic anticipation in Behcets syndrome. Ann Rheum Dis. 1998 Jan. 57(1):45-8. [QxMD MEDLINE Link]. ...
Salah satu dari jenis penyakit Autoimun adalah Behcets Syndrome/ Behcets Disease. Seperti penyakit Autoimun lainnya, Behcet ... Umumnya, penderita Behcet akan mengalami ruam-ruam kemerahan pada kulitnya. Kadang berbentuk titik-titik, ruam seperti jerawat ... Gejala yang dirasakan masing-masing penderita Behcet sangat beragam tergantung bagian mana yang dominan diserang. Namun, ... maka Behcet menyerang sistem pembuluh darah tipis teruatama di daerah mata, kulit, dan rongga mulut.. ...
Fever is taken to be rare in Behcets syndrome (BS) and when present it is usually considered to be associated with vascular ...
Restless leg syndrome in Neuro-Behcets and Behcets disease. M. Kuzu Kumcu, S. Erdoğan, M. Sorgun, C. Yücesan (Ankara, Turkey) ... Restless leg syndrome in Neuro-Behcets and Behcets disease [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www. ... Objective: The goal of this study is the comparison of the restless leg syndrome frequency in the BD and NBD patients and also ... Background: A bunch of studies showed that restless leg syndrome (RLS) may be more frequent in the neuro-Behçets disease (NBD ...
Behçets syndrome is a multisystem disease complex, the major manifestations of which are oral and genital ulcers, arthritis, ... Proliferative Glomerulonephritis With Crescent Formation in Behcets Syndrome. Phillip J. Olsson, MD; Eoin Gaffney, MB, BCh; ... Proliferative Glomerulonephritis With Crescent Formation in Behcets Syndrome. Arch Intern Med. 1980;140(5):713-714. doi: ... Behçets syndrome is a multisystem disease complex, the major manifestations of which are oral and genital ulcers, arthritis, ...
Dalvi SR, Yildirim R, Yazici Y (December 2012). "Behcets Syndrome". Drugs. 72 (17): 2223-41. doi:10.2165/11641370-000000000- ... MAGIC syndrome is a possible variant of Behçets disease, and is associated with aphthous-like ulceration. The name stands for ... Synonyms for major RAS include Suttons ulcers (named after Richard Lightburn Sutton), Suttons disease, Suttons syndrome and ... "mouth and genital ulcers with inflamed cartilage" (relapsing polychondritis). PFAPA syndrome is a rare condition that tends to ...
Behcet Syndrome / cerebrospinal fluid * Behcet Syndrome / diagnosis* * Behcet Syndrome / pathology * Brain / pathology* ... Clinical characteristics of neuro-Behcets disease in Japan: a multicenter retrospective analysis Mod Rheumatol. 2012 Jun;22(3 ...
Behcets Syndrome * Berry Aneurysm see Brain Aneurysm * Bleeding * Bleeding Disorders * Blood * Blood Cells see Blood; Blood ... Hypereosinophilic Syndrome see Eosinophilic Disorders * Hyperlipidemia see Cholesterol; Cholesterol Levels: What You Need to ...
Behcet Syndrome (Orphan). Orphan sponsor. *AR Scientific, Inc, 1100 Orthodox Street, Philadelphia, PA 19124 ... Elranatamab causes cytokine release syndrome (CRS) that may suppress activity of CYP enzymes, resulting in increased exposure ... Talquetamab causes cytokine release syndrome (CRS) that may suppress activity of CYP enzymes, resulting in increased exposure ... Elranatamab causes cytokine release syndrome (CRS) that may suppress activity of CYP enzymes, resulting in increased exposure ...
Pharmacotherapy for Behcets syndrome. Saenz A, Ausejo M, Shea B, Wells G, Welch V, Tugwell P. Saenz A, et al. Cochrane ...
Behcets syndrome. *Scleroderma. *Help in the diagnosis of joint and muscle pain ...
This category is reserved for those conditions and diseases which are considered syndromes or otherwise attack multiple body ... Behcets Syndrome Society The Behcets Syndrome Society is a non-profit organisation which provides information on the ... Chronic Fatigue Syndrome. Cystic Fibrosis. Fibromyalgia. Kawasaki Syndrome. Leprosy. Lyme Disease. Toxic Shock Syndrome. West ... American Behcets Disease Association The American Behcets Disease Association is a non-profit organization which provides ...
For three separate autoimmune events (Behcets syndrome, Raynauds disease, and type 1 diabetes), statistically significant ... Abbreviations: FDA = Food and Drug Administration; GBS = Guillain-Barré syndrome; HPV = human papillomavirus; HPV4 = ... statistically significant increased risks were observed for any of the prespecified endpoints including Guillain-Barré syndrome ...
ClinVar Annotator: match by term: Behcet disease , ClinVar Annotator: match by term: Behcets syndrome. ClinVar. PMID:25741868 ... ClinVar Annotator: match by term: Behcet disease. ClinVar. PMID:25741868 PMID:28492532 PMID:28814775 PMID:31411330. NCBI chr10: ... ClinVar Annotator: match by term: Behcet disease. ClinVar. PMID:25741868. NCBI chr 9:42,727,416...42,760,971 Ensembl chr 9: ... ClinVar Annotator: match by term: Behcet disease. DNA:mutations:cds:p.G908R,p.R702W,p.L1007fsinsC(human). ClinVar. RGD. PMID: ...
Behcets syndrome. 2.929 reviews. Condition. Dermatitis herpetiformis. 2.67 reviews. Condition ...
Ugurlu S, Ucar D, Seyahi E, Hatemi G, Yurdakul S. Canakinumab in a patient with juvenile Behcets syndrome with refractory eye ... A controlled trial of azathioprine in Behcets syndrome. N Engl J Med. 1990;322(5):281-285. ... The Sjögrens Syndrome Damage Index - a damage index for use in clinical trials and observational studies in primary Sjögrens ... Long-term efficacy of infliximab in refractory posterior uveitis of Behcets disease: a 24-month follow-up study. Rheumatology ...
Did you get a pustule at your blood draw site? Consider Behcets Syndrome. The original description of Behçets syndrome ...
Currently Used Biologic Agents in the Management of Behcets Syndrome Journal: Current Medicinal Chemistry Volume: 22 Page: ...
Rarely, they are associated with celiac disease, Crohns disease, Behcets syndrome, or HIV. ...
Patient experience of genitourinary syndrome of menopause. Take Quiz. Symptoms of genitourinary syndrome of menopause. Take ... Behcets syndrome: Types of manifestations. Take Quiz. Pain/Pain Relief. Quiz Updated Opioid Prescribing Guidelines. Take Quiz ... Hepatopulmonary syndrome symptoms. Take Quiz. USPSTF recommendations: Screening for celiac disease in asymptomatic persons. ...
Patient experience of genitourinary syndrome of menopause. Take Quiz. Symptoms of genitourinary syndrome of menopause. Take ... Behcets syndrome: Types of manifestations. Take Quiz. Pain/Pain Relief. Quiz Updated Opioid Prescribing Guidelines. Take Quiz ... Hepatopulmonary syndrome symptoms. Take Quiz. USPSTF recommendations: Screening for celiac disease in asymptomatic persons. ...
The probable pathogenesis of erythema nodosum-like lesions in Behcets syndrome. Journal of Clinical Electron Microscopy. 1988 ...
Additional disorders include Behcet syndrome, pediatric graft-versus-host disease, Henoch-Schonlein purpura, chronic ... This can result in short bowel syndrome. Short bowel syndrome is a complex disease that occurs due to the physical loss or the ... Related Rare Diseases: Pediatric Crohns Disease, Superior Mesenteric Artery Syndrome, Ogilvie syndrome, ... ... NORD has a separate report on short bowel syndrome.. Surgery may also be indicated for severe narrowing or obstruction of the ...
  • The Behcet's Syndrome International Study Group Criteria calculator is created by QxMD. (medscape.com)
  • Turkish dermatologist, Hulusi Behcet (1889-1948) recognized and reported in 1937 symptoms of Behcet's syndrome. (targetwoman.com)
  • In the absence of a cure or a single test to definitely determine Behcet's syndrome or Behcet's disease , educate about the syndrome to seek prompt medical attention for treatment. (targetwoman.com)
  • Behcet's syndrome is rare. (targetwoman.com)
  • Though the clinical feature of auto immunity is absent, Behcet's syndrome is classified as an autoimmune disease as it has various aspects related to autoimmune disease. (targetwoman.com)
  • The most common symptom of Behcet's syndrome is the regular occurrence of ulcers in the mouth and genitals. (targetwoman.com)
  • Sudden inflammation of the eyes is a common symptom of Behcet's syndrome. (targetwoman.com)
  • For patient education information, see Behcet's Syndrome . (medscape.com)
  • Qiuthinks: Apa sih Behcet's Syndrome? (naddasalma.com)
  • Salah satu dari jenis penyakit Autoimun adalah Behcet's Syndrome/ Behcet's Disease. (naddasalma.com)
  • Fever is taken to be rare in Behcet's syndrome (BS) and when present it is usually considered to be associated with vascular disease. (istanbul.edu.tr)
  • Consider Behcet's Syndrome. (mydoctorsf.com)
  • The probable pathogenesis of erythema nodosum-like lesions in Behcet's syndrome. (go.jp)
  • Articles cover thalidomide therapy for multiple myeloma, Behcet's Syndrome, and leukemia. (handsonhealth-sc.org)
  • Eighteen patients (33%) had a flare of their autoimmune disease including 4 of 7 with rheumatoid arthritis, 3 of 6 with psoriasis, 5 of 10 with inflammatory bowel disease, 3 of 19 with thyroiditis, 1 of 1 with Sjogren's syndrome, 1 of 1 with polymyalgia and 1 of 1 with Behcet's syndrome and psoriasis. (bmj.com)
  • In addition, it has been found to successfully treat complications of leprosy, systemic lupus erythematosus (SLE), Behcet's syndrome, Langerhans cell histiocytosis, and graft vs. host disease, due to its potent anti-inflammatory properties. (emra.org)
  • Periodic Fever Syndromes (PFS) (also known as monogenic autoinflammatory syndromes) is a collective group of disorders highlighted by recurrent fever and inflammatory episodes. (preventiongenetics.com)
  • The review provided a comprehensive report on the use of scRNA-seq in understanding the following systemic AID: rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, primary Sjogren's syndrome, Kawasaki disease, systemic sclerosis, macrophage activation syndrome, multisystem inflammatory syndrome in children, and Behcet's disease. (news-medical.net)
  • It can also occur due to certain rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematosus (SLE/ lupus) or Sjogrens syndrome. (outsourcestrategies.com)
  • About 1000 patients with rheumatoid arthritis, systemic lupus erythematosus, and vasculitic syndrome, etc. are visiting us for treatment. (okayama-u.ac.jp)
  • MS and other demyelinating processes, such as transverse myelitis and optic neuritis (which may be clinically isolated cases or be part of the clinical spectrum of MS), are sometimes difficult to differentiate from CNS involvement in systemic autoimmune diseases like systemic lupus erythematosus (SLE), antiphospholipid syndrome (APS), Sjoegren's syndrome (SS), and Adamantiades-Behcet disease (BD). (bmj.com)
  • Behcet syndrome (BS) is a chronic systemic inflammatory disorder involving vessels of all sizes, characterized by episodes relative of oral and / or genital ulcers, as well as cutaneous lesions. (ifn-a.com)
  • Acute febrile neutrophilic dermatosis (Sweet syndrome) is a reactive process (a hypersensitivity reaction) that occurs in response to systemic factors, such as hematologic disease, infection, inflammation, vaccination, or drug exposure. (medscape.com)
  • Cutaneous manifestations can occur in up 75% of patients with Behcet disease and can range from acneiform lesions, to nodules and erythema nodosum. (medscape.com)
  • Retinal arterial and venous lesions are prognostic indicators for blindness, which is a major complication of Behçet syndrome. (medscape.com)
  • Background Behçet's syndrome (BS) is a multifactorial, polygenic, autoinflammatory vasculitis characterized by recurrent oral and genital ulcers, uveitis, skin lesions, and arthritis. (researchsquare.com)
  • Millard Gubler syndrome is one of the brainstem syndromes that occurs due to lesions involving the ventral part of the caudal pons. (bvsalud.org)
  • Characteristics that distinguish the lesions of Sweet syndrome from other neutrophilic dermatosis are healing of the lesions without scarring and an absence of vasculitis. (medscape.com)
  • The functional properties of neutrophils, rather than the absolute number, is thought to be significant because patients with Sweet syndrome due to G-CSF develop lesions as the neutrophil count rapidly increases, despite the absolute neutrophil count being low. (medscape.com)
  • Behçet syndrome is characterized by recurrent aphthous ulcers, genital ulcers, and uveitis or retinal vasculitis. (medscape.com)
  • In Behçet syndrome, the basic lesion is vasculitis. (medscape.com)
  • However, recent reports suggest that vasculitis should not exclude the diagnosis since it has been shown to occur in many patients with Sweet syndrome, which may represent an epiphenomenon instead of a primary immune-mediated process. (medscape.com)
  • In this retrospective study we performed a chart review of patients with a confirmed diagnosis of BS who were followed at the Behçet's syndrome outpatient clinic, Rheumatology Research Center, Shariati Hospital, Tehran, Iran, between 2015 and 2017. (researchsquare.com)
  • The diagnosis of Sweet syndrome is based on both clinical and histopathologic findings. (medscape.com)
  • In this episode, we review the high-yield topic of Behcet Syndrome from the Rheumatology section. (medbullets.com)
  • The syndrome carries the name of the Turkish dermatologist Hulusi Behçet, who, in 1937, described a syndrome of recurrent aphthous ulcers , genital ulcerations, and uveitis leading to blindness. (medscape.com)
  • The unit has extensive experience in treating patients with collagen diseases and internal organ complications (lung and heart involvement in collagen diseases, pulmonary hypertension due to collagen disease, Raynaud's syndrome, and gastrointestinal complications in autoimmune diseases). (rambam.org.il)
  • Behçet syndrome is a multisystem disease of unknown etiology probably first described by Hippocrates in the 5th century. (medscape.com)
  • Behçet's syndrome is a multisystem disease complex, the major manifestations of which are oral and genital ulcers, arthritis, uveitis, and skin eruptions. (jamanetwork.com)
  • Onset of PFS occurs during the first year of life or early childhood with only familial mediterranean fever (FMF) and tumor necrosis factor receptor-associated periodic syndrome having cases of adult onset described. (preventiongenetics.com)
  • The original description of Behçet's syndrome included recurring genital and oral ulcerations and relapsing uveitis. (mydoctorsf.com)
  • An acute isolated neurological syndrome presents the biggest diagnostic problem, since it is common in MS, but can also be the only feature or first manifestation in SLE, APS, SS, and BD. (bmj.com)
  • Acute febrile neutrophilic dermatosis, also termed Sweet syndrome, is a reactive process characterized by the abrupt onset of tender, red-to-purple papules, and nodules that coalesce to form plaques. (medscape.com)
  • Acute febrile neutrophilic dermatosis (Sweet syndrome) is uncommon but not rare. (medscape.com)
  • This category is reserved for those conditions and diseases which are considered syndromes or otherwise attack multiple body systems. (avivadirectory.com)
  • Described in 1964 by Robert Sweet, the entity currently recognized as Sweet syndrome ranges from classic Sweet disease, which occurs in young women after a mild respiratory illness, to a more aggressive neutrophilic process, which may be associated with other inflammatory diseases or malignancy. (medscape.com)
  • Neutrophilic hyperfunction is observed in patients with Behçet syndrome with neutrophilic infiltration of skin at the site of a prick with a sterile needle (the pathergy test). (medscape.com)
  • CNS: Neurologic involvement is one of the most serious manifestations of Behçet syndrome, occurring in 10-30% of patients and carrying a poor prognosis. (medscape.com)
  • Morbus Behcet or Silk Road disease is the other name for Behcet Syndrome or disease. (targetwoman.com)
  • [ 1 ] IL-6 has been shown to be elevated and IL-10 decreased in patients with Behçet syndrome compared with controls, and IL-6 is elevated in those with active disease. (medscape.com)
  • A bunch of studies showed that restless leg syndrome (RLS) may be more frequent in the neuro-Behçet's disease (NBD). (mdsabstracts.org)
  • G-CSF levels in peripheral blood are increased in patients with active Sweet syndrome, suggesting that high levels of G-CSF may one day be a useful indicator of activity level of the disease. (medscape.com)
  • AIDS-like syndrome: AIDS-like disease (illness) (syndrome) ARC AIDS-related complex Pre-AIDS AIDS-related conditions Prodromal-AIDS 3. (cdc.gov)
  • These GWASs demonstrate that the most common non-HLA association is with the interleukin (IL)-10 and IL23R loci and underline the essential role of the IL-10 and IL23/17 pathways in the pathogenesis of Behçet syndrome. (medscape.com)
  • We wanted to present a case of Millard Gubler syndrome, which developed due to Behçet's syndrome lesion in the pons ventral region in a patient who presented with limitation of outward gaze on the left, inability to close the left eye completely, inability to completely wrinkle the left side of the forehead, and loss of contralateral muscle strength. (bvsalud.org)
  • The Co-Cure website is dedicate to finding a cure for Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM). (avivadirectory.com)
  • In general, Sweet syndrome responds dramatically to oral corticosteroids and may improve or resolve with treatment of the underlying condition. (medscape.com)
  • Without treatment, the syndrome may persist for weeks or months and then improves without leaving scars. (medscape.com)
  • Classic and atypical polymyalgia rheumatica, are different syndromes? (unican.es)
  • The goal of this study is the comparison of the restless leg syndrome frequency in the BD and NBD patients and also to investigate whether depression and anxiety have any effect on the presence of RLS in both groups. (mdsabstracts.org)
  • Frequency data for Behçet syndrome should be considered suspect because of problems with case ascertainment. (medscape.com)
  • There is a wide range of phenotypic variations in Behçet syndrome, which may be due to genetic and ethnic differences. (medscape.com)
  • A report of 2 brothers who developed Sweet syndrome in the neonatal period also supports a genetic predisposition. (medscape.com)
  • We describe a patient with Behçet's syndrome who experienced diffuse proliferative glomerulonephritis with epithelial cell crescent formation in 75% of glomeruli examined. (jamanetwork.com)
  • Behçet syndrome is thought to be more common along the ancient Silk Road, extending from Asia to the Mediterranean. (medscape.com)