Diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the BRACHIAL PLEXUS. Clinical manifestations include regional pain, PARESTHESIA; MUSCLE WEAKNESS, and decreased sensation (HYPESTHESIA) in the upper extremity. These disorders may be associated with trauma (including BIRTH INJURIES); THORACIC OUTLET SYNDROME; NEOPLASMS; NEURITIS; RADIOTHERAPY; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp1351-2)
A syndrome associated with inflammation of the BRACHIAL PLEXUS. Clinical features include severe pain in the shoulder region which may be accompanied by MUSCLE WEAKNESS and loss of sensation in the upper extremity. This condition may be associated with VIRUS DISEASES; IMMUNIZATION; SURGERY; heroin use (see HEROIN DEPENDENCE); and other conditions. The term brachial neuralgia generally refers to pain associated with brachial plexus injury. (From Adams et al., Principles of Neurology, 6th ed, pp1355-6)
The large network of nerve fibers which distributes the innervation of the upper extremity. The brachial plexus extends from the neck into the axilla. In humans, the nerves of the plexus usually originate from the lower cervical and the first thoracic spinal cord segments (C5-C8 and T1), but variations are not uncommon.
Ulnar neuropathies caused by mechanical compression of the nerve at any location from its origin at the BRACHIAL PLEXUS to its terminations in the hand. Common sites of compression include the retroepicondylar groove, cubital tunnel at the elbow (CUBITAL TUNNEL SYNDROME), and Guyon's canal at the wrist. Clinical features depend on the site of injury, but may include weakness or paralysis of wrist flexion, finger flexion, and ulnar innervated intrinsic hand muscles, and impaired sensation over the ulnar aspect of the hand, fifth finger, and ulnar half of the ring finger. (Joynt, Clinical Neurology, 1995, Ch51, p43)
Mechanical or anoxic trauma incurred by the infant during labor or delivery.
A villous structure of tangled masses of BLOOD VESSELS contained within the third, lateral, and fourth ventricles of the BRAIN. It regulates part of the production and composition of CEREBROSPINAL FLUID.
Paralysis of an infant resulting from injury received at birth. (From Dorland, 27th ed)
Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain.
A major nerve of the upper extremity. The fibers of the musculocutaneous nerve originate in the lower cervical spinal cord (usually C5 to C7), travel via the lateral cord of the brachial plexus, and supply sensory and motor innervation to the upper arm, elbow, and forearm.
Surgical reinnervation of a denervated peripheral target using a healthy donor nerve and/or its proximal stump. The direct connection is usually made to a healthy postlesional distal portion of a non-functioning nerve or implanted directly into denervated muscle or insensitive skin. Nerve sprouts will grow from the transferred nerve into the denervated elements and establish contact between them and the neurons that formerly controlled another area.
Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
A network of nerve fibers originating in the upper four CERVICAL SPINAL CORD segments. The cervical plexus distributes cutaneous nerves to parts of the neck, shoulders, and back of the head. It also distributes motor fibers to muscles of the cervical SPINAL COLUMN, infrahyoid muscles, and the DIAPHRAGM.
A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)
The ventral rami of the thoracic nerves from segments T1 through T11. The intercostal nerves supply motor and sensory innervation to the thorax and abdomen. The skin and muscles supplied by a given pair are called, respectively, a dermatome and a myotome.
A neurovascular syndrome associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the superior thoracic outlet. This may result from a variety of anomalies such as a CERVICAL RIB, anomalous fascial bands, and abnormalities of the origin or insertion of the anterior or medial scalene muscles. Clinical features may include pain in the shoulder and neck region which radiates into the arm, PARESIS or PARALYSIS of brachial plexus innervated muscles, PARESTHESIA, loss of sensation, reduction of arterial pulses in the affected extremity, ISCHEMIA, and EDEMA. (Adams et al., Principles of Neurology, 6th ed, pp214-5).
The articulation between the head of the HUMERUS and the glenoid cavity of the SCAPULA.

The exacerbating effect of insulin-induced hypoglycemia on spontaneous peripheral neuropathy in aged B6C3F1 mice. (1/102)

The effect of insulin-induced hypoglycemia on spontaneous peripheral neuropathy in aged mice was examined. Ninety-five-week-old female B6C3F1 mice were infused subcutaneously for 2 weeks with 40 or 80 IU/kg/day of insulin with a micro osmotic pump. Blood glucose level was decreased during the infusion (4.3-6.8 mmol/L in mice receiving 40 IU/kg/day of insulin or 2.4-5.4 mmol/L in mice receiving 80 IU/kg/day of insulin versus 6.5-7.6 mmol/L in control mice). In histopathological examination, axonal degeneration and/or remyelination were observed in a small number of nerve fibers of control mice. Similar nerve fiber lesions were observed in mice receiving 40 IU/kg/day of insulin, whereas severer lesions with an increase in segmental axonal degeneration of nerve fibers were observed in 4/7 mice receiving 80 IU/kg/day of insulin. These findings suggest that spontaneous peripheral neuropathy in aged mice is exacerbated by sustained hypoglycemia induced by insulin treatment.  (+info)

Scapulothoracic stabilisation for winging of the scapula using strips of autogenous fascia lata. (2/102)

We have used a modified technique in five patients to correct winging of the scapula caused by injury to the brachial plexus or the long thoracic nerve during transaxillary resection of the first rib. The procedure stabilises the scapulothoracic articulation by using strips of autogenous fascia lata wrapped around the 4th, 6th and 7th ribs at least two, and preferably three, times. The mean age of the patients at the time of operation was 38 years (26 to 47) and the mean follow-up six years and four months (three years and three months to 11 years). Satisfactory stability was achieved in all patients with considerable improvement in shoulder function. There were no complications.  (+info)

Function of the upper limb after surgery for obstetric brachial plexus palsy. (3/102)

We reviewed a consecutive series of 33 infants who underwent surgery for obstetric brachial plexus palsy at a mean age of 4.7 months. Of these, 13 with an upper palsy and 20 with a total palsy were treated by nerve reconstruction. Ten were treated by muscle transfer to the shoulder or elbow, and 16 by tendon transfer to the hand. The mean postoperative follow-up was 4 years 8 months. Ten of the 13 children (70%) with an upper palsy regained useful shoulder function and 11 (75%) useful elbow function. Of the 20 children with a total palsy, four (20%) regained useful shoulder function and seven (35%) useful elbow function. Most patients with a total palsy had satisfactory sensation of the hand, but only those with some preoperative hand movement regained satisfactory grasp. The ability to incorporate the palsied arm and hand into a co-ordinated movement pattern correlated with the sensation and prehension of the hand, but not with shoulder and elbow function.  (+info)

Restoration of sensory function and lack of long-term chronic pain syndromes after brachial plexus injury in human neonates. (4/102)

Obstetric complications are a common cause of brachial plexus injuries in neonates. Failure to restore sensation leads to trophic injuries and poor limb function. It is not known whether the infant suffers chronic neuropathic or spinal cord root avulsion pain; in adults, chronic pain is usual after spinal root avulsion injuries, and this is often intractable. The plexus is repaired surgically in severe neonatal injures; if no spontaneous recovery has occurred by 3 months, and if neurophysiological investigations point to poor prognosis, then nerve trunk injures are grafted, while spinal cord root avulsion injuries are treated by transferring an intact neighbouring nerve (e.g. intercostal) to the distal stump of the damaged nerve, in an attempt to restore sensorimotor function. Using a range of non-invasive quantitative measures validated in adults, including mechanical, thermal and vibration perception thresholds, we have assessed for the first time sensory and cholinergic sympathetic function in 24 patients aged between 3 and 23 years, who had suffered severe brachial plexus injury at birth. While recovery of function after spinal root avulsion was related demonstrably to surgery, there were remarkable differences from adults, including excellent restoration of sensory function (to normal limits in all dermatomes for at least one modality in 16 out of 20 operated cases), and evidence of exquisite CNS plasticity, i.e. perfect localization of restored sensation in avulsed spinal root dermatomes, now presumably routed via nerves that had been transferred from a distant spinal region. Sensory recovery exceeded motor or cholinergic sympathetic recovery. There was no evidence of chronic pain behaviour or neuropathic syndromes, although pain was reported normally to external stimuli in unaffected regions. We propose that differences in neonates are related to later maturation of injured fibres, and that CNS plasticity may account for their lack of long-term chronic pain after spinal root avulsion injury.  (+info)

Ultrasound diagnosis of shoulder congruity in chronic obstetric brachial plexus palsy. (5/102)

Ultrasound (US) was used to determine the congruity of the shoulder in 22 children with a deformity of the shoulder secondary to chronic obstetric brachial plexus palsy. There were 11 boys and 11 girls with a mean age of 4.75 years (0.83 to 13.92). The shoulder was scanned in the axial plane using a posterior approach with the arm internally rotated. The humeral head was classified as being either congruent or incongruent. The US appearance was compared with that on clinical examination and related to the intraoperative findings. All 17 shoulders diagnosed as incongruent on US were found to be incongruent at operation, whereas three diagnosed as congruent by US were found to be incongruent at operation. The diagnostic accuracy of US for the identification of shoulder incongruity was 82% when compared with the findings at surgery. US is a valuable, but not infallible tool, for the detection of incongruity of the shoulder.  (+info)

A case of multiple schwannomas of the trigeminal nerves, acoustic nerves, lower cranial nerves, brachial plexuses and spinal canal: schwannomatosis or neurofibromatosis? (6/102)

In most cases, while schwannoma is sporadically manifested as a single benign neoplasm, the presence of multiple schwannomas in one patient is usually indicative of neurofibromatosis 2. However, several recent reports have suggested that schwannomatosis itself may also be a distinct clinical entity. This study examines an extremely rare case of probable schwannomatosis associated with intracranial, intraspinal and peripheral involvements. A 63-year-old woman presented with a seven-year history of palpable lumps on both sides of the supraclavicular area and hearing impairment in both ears. On physical examination, no skin manifestations were evident. Facial sensory change, deafness in the left ear and decreased gag reflex were revealed by neurological examination. Magnetic resonance imaging revealed multiple lesions of the trigeminal nerves, acoustic nerves, lower cranial nerves, spinal accessory nerve, brachial plexuses, and spinal nerves. Pathological examination of tumors from the bilateral brachial plexuses, the spinal nerve in the T8 spinal position and the neck mass revealed benign schwannomas. Following is this patient case report of multiple schwannomas presenting with no skin manifestations of neurofibromatosis.  (+info)

Cervico thoracic junction spinal tuberculosis presenting as radiculopathy. (7/102)

A case of cervico thoracic junctional area spinal tuberculosis presenting as painful radiculitis of the upper extremity is reported. The predominant symptom of radicular pain and muscle weakness in the hand, along with a claw deformity, led to considerable delay in diagnosis. The presence of advanced bone destruction with severe instability was demonstrated on the MRI scan done later. Surgical management by radical anterior debridement and fusion, along with chemotherapy, led to resolution of the upper extremity symptoms. The brachial plexus radiculopathy secondary to tuberculosis has not been reported. The absence of myelopathic signs even in the presence of advanced bone destruction, thecal compression and instability is uncommon in adults.  (+info)

Retroversion of the humeral head in children with an obstetric brachial plexus lesion. (8/102)

We undertook a prospective MRI study to measure the retroversion of the humeral head in 33 consecutive infants with a mean age of 1 year 10 months (3 months to 7 years 4 months) who had an obstetric brachial plexus lesion (OBPL). According to a standardised MRI protocol both shoulders and humeral condyles were examined and the shape of the glenoid and humeral retroversion determined. The mean humeral retroversion of the affected shoulder was significantly increased compared with the normal contralateral side (-28.4 +/- 12.5 degrees v -21.5 +/- 15.1 degrees, p = 0.02). This increase was found only in the children over the age of 12 months. In this group humeral retroversion was -29.9 +/- 12.9 degrees compared with -19.6 +/- 15.6 degrees in the normal shoulder (p = 0.009), giving a mean difference of 10.3 degrees (95% confidence interval 3.3 to 17.3). This finding is of importance when considering the operative treatment for subluxation of the shoulder in children with an OBPL.  (+info)

Brachial plexus neuropathies refer to a group of conditions that affect the brachial plexus, which is a network of nerves that originates from the spinal cord in the neck and travels down the arm. These nerves are responsible for providing motor and sensory function to the shoulder, arm, and hand.

Brachial plexus neuropathies can occur due to various reasons, including trauma, compression, inflammation, or tumors. The condition can cause symptoms such as pain, numbness, weakness, or paralysis in the affected arm and hand.

The specific medical definition of brachial plexus neuropathies is:

"A group of conditions that affect the brachial plexus, characterized by damage to the nerves that results in motor and/or sensory impairment of the upper limb. The condition can be congenital or acquired, with causes including trauma, compression, inflammation, or tumors."

Brachial plexus neuritis, also known as Parsonage-Turner syndrome or neuralgic amyotrophy, is a medical condition characterized by inflammation and damage to the brachial plexus. The brachial plexus is a network of nerves that originates from the spinal cord in the neck and travels down the arm, controlling movement and sensation in the shoulder, arm, and hand.

In Brachial plexus neuritis, the insulating covering of the nerves (myelin sheath) is damaged or destroyed, leading to impaired nerve function. The exact cause of this condition is not fully understood, but it can be associated with viral infections, trauma, surgery, or immunological disorders.

Symptoms of Brachial plexus neuritis may include sudden onset of severe pain in the shoulder and arm, followed by weakness or paralysis of the affected muscles. There may also be numbness, tingling, or loss of sensation in the affected areas. In some cases, recovery can occur spontaneously within a few months, while others may experience persistent weakness or disability. Treatment typically involves pain management, physical therapy, and in some cases, corticosteroids or other medications to reduce inflammation.

The brachial plexus is a network of nerves that originates from the spinal cord in the neck region and supplies motor and sensory innervation to the upper limb. It is formed by the ventral rami (branches) of the lower four cervical nerves (C5-C8) and the first thoracic nerve (T1). In some cases, contributions from C4 and T2 may also be included.

The brachial plexus nerves exit the intervertebral foramen, pass through the neck, and travel down the upper chest before branching out to form major peripheral nerves of the upper limb. These include the axillary, radial, musculocutaneous, median, and ulnar nerves, which further innervate specific muscles and sensory areas in the arm, forearm, and hand.

Damage to the brachial plexus can result in various neurological deficits, such as weakness or paralysis of the upper limb, numbness, or loss of sensation in the affected area, depending on the severity and location of the injury.

Ulnar nerve compression syndromes refer to a group of conditions characterized by the entrapment or compression of the ulnar nerve, leading to various symptoms. The ulnar nerve provides motor function to the hand muscles and sensation to the little finger and half of the ring finger.

There are several sites along the course of the ulnar nerve where it can become compressed, resulting in different types of ulnar nerve compression syndromes:

1. Cubital Tunnel Syndrome: This occurs when the ulnar nerve is compressed at the elbow, within the cubital tunnel - a narrow passage located on the inner side of the elbow. Symptoms may include numbness and tingling in the little finger and half of the ring finger, weakness in gripping or pinching, and pain or discomfort in the elbow.

2. Guyon's Canal Syndrome: This type of ulnar nerve compression syndrome happens when the nerve is compressed at the wrist, within the Guyon's canal. Causes can include ganglion cysts, bone fractures, or repetitive motion injuries. Symptoms may include numbness and tingling in the little finger and half of the ring finger, weakness or paralysis in the hand muscles, and muscle wasting in severe cases.

Treatment for ulnar nerve compression syndromes depends on the severity and location of the compression. Conservative treatments such as physical therapy, bracing, or anti-inflammatory medications may be recommended for milder cases. Severe or persistent symptoms may require surgical intervention to relieve the pressure on the ulnar nerve.

Birth injuries refer to damages or injuries that a baby suffers during the birthing process. These injuries can result from various factors, such as mechanical forces during delivery, medical negligence, or complications during pregnancy or labor. Some common examples of birth injuries include:

1. Brachial plexus injuries: Damage to the nerves that control movement and feeling in the arms and hands, often caused by excessive pulling or stretching during delivery.
2. Cephalohematoma: A collection of blood between the skull and the periosteum (the membrane covering the bone), usually caused by trauma during delivery.
3. Caput succedaneum: Swelling of the soft tissues of the baby's scalp, often resulting from pressure on the head during labor and delivery.
4. Fractures: Broken bones, such as a clavicle or skull fracture, can occur due to mechanical forces during delivery.
5. Intracranial hemorrhage: Bleeding in or around the brain, which can result from trauma during delivery or complications like high blood pressure in the mother.
6. Perinatal asphyxia: A lack of oxygen supply to the baby before, during, or immediately after birth, which can lead to brain damage and other health issues.
7. Subconjunctival hemorrhage: Bleeding under the conjunctiva (the clear membrane covering the eye), often caused by pressure on the head during delivery.
8. Spinal cord injuries: Damage to the spinal cord, which can result in paralysis or other neurological issues, may occur due to excessive force during delivery or medical negligence.

It's important to note that some birth injuries are unavoidable and may not be a result of medical malpractice. However, if a healthcare provider fails to provide the standard of care expected during pregnancy, labor, or delivery, they may be held liable for any resulting injuries.

The choroid plexus is a network of blood vessels and tissue located within each ventricle (fluid-filled space) of the brain. It plays a crucial role in the production of cerebrospinal fluid (CSF), which provides protection and nourishment to the brain and spinal cord.

The choroid plexus consists of modified ependymal cells, called plexus epithelial cells, that line the ventricular walls. These cells have finger-like projections called villi, which increase their surface area for efficient CSF production. The blood vessels within the choroid plexus transport nutrients, ions, and water to these epithelial cells, where they are actively secreted into the ventricles to form CSF.

In addition to its role in CSF production, the choroid plexus also acts as a barrier between the blood and the central nervous system (CNS), regulating the exchange of substances between them. This barrier function is primarily attributed to tight junctions present between the epithelial cells, which limit the paracellular movement of molecules.

Abnormalities in the choroid plexus can lead to various neurological conditions, such as hydrocephalus (excessive accumulation of CSF) or certain types of brain tumors.

Obstetric paralysis is a specific type of paralysis that can occur as a result of complications during childbirth. It is also known as "birth paralysis" or "puerperal paralysis."

The condition is typically caused by nerve damage or trauma to the brachial plexus, which is a network of nerves that runs from the spinal cord in the neck and provides movement and sensation to the shoulders, arms, and hands. Obstetric paralysis can occur when the brachial plexus is stretched or compressed during childbirth, particularly in difficult deliveries where forceps or vacuum extraction may be used.

There are several types of obstetric paralysis, including:

* Erb's palsy: This type of obstetric paralysis affects the upper brachial plexus and can cause weakness or paralysis in the arm, particularly the shoulder and elbow.
* Klumpke's palsy: This type of obstetric paralysis affects the lower brachial plexus and can cause weakness or paralysis in the hand and forearm.
* Total brachial plexus injury: This is a rare but severe form of obstetric paralysis that involves injury to all of the nerves in the brachial plexus, resulting in complete paralysis of the arm.

The severity of obstetric paralysis can vary widely, from mild weakness to complete paralysis. In some cases, the condition may resolve on its own within a few months, while in other cases, surgery or physical therapy may be necessary to help restore function.

Diabetic neuropathies refer to a group of nerve disorders that are caused by diabetes. High blood sugar levels can injure nerves throughout the body, but diabetic neuropathies most commonly affect the nerves in the legs and feet.

There are four main types of diabetic neuropathies:

1. Peripheral neuropathy: This is the most common type of diabetic neuropathy. It affects the nerves in the legs and feet, causing symptoms such as numbness, tingling, burning, or shooting pain.
2. Autonomic neuropathy: This type of neuropathy affects the autonomic nerves, which control involuntary functions such as heart rate, blood pressure, digestion, and bladder function. Symptoms may include dizziness, fainting, digestive problems, sexual dysfunction, and difficulty regulating body temperature.
3. Proximal neuropathy: Also known as diabetic amyotrophy, this type of neuropathy affects the nerves in the hips, thighs, or buttocks, causing weakness, pain, and difficulty walking.
4. Focal neuropathy: This type of neuropathy affects a single nerve or group of nerves, causing symptoms such as weakness, numbness, or pain in the affected area. Focal neuropathies can occur anywhere in the body, but they are most common in the head, torso, and legs.

The risk of developing diabetic neuropathies increases with the duration of diabetes and poor blood sugar control. Other factors that may contribute to the development of diabetic neuropathies include genetics, age, smoking, and alcohol consumption.

A nerve block is a medical procedure in which an anesthetic or neurolytic agent is injected near a specific nerve or bundle of nerves to block the transmission of pain signals from that area to the brain. This technique can be used for both diagnostic and therapeutic purposes, such as identifying the source of pain, providing temporary or prolonged relief, or facilitating surgical procedures in the affected region.

The injection typically contains a local anesthetic like lidocaine or bupivacaine, which numbs the nerve, preventing it from transmitting pain signals. In some cases, steroids may also be added to reduce inflammation and provide longer-lasting relief. Depending on the type of nerve block and its intended use, the injection might be administered close to the spine (neuraxial blocks), at peripheral nerves (peripheral nerve blocks), or around the sympathetic nervous system (sympathetic nerve blocks).

While nerve blocks are generally safe, they can have side effects such as infection, bleeding, nerve damage, or in rare cases, systemic toxicity from the anesthetic agent. It is essential to consult with a qualified medical professional before undergoing this procedure to ensure proper evaluation, technique, and post-procedure care.

The musculocutaneous nerve is a peripheral nerve that originates from the lateral cord of the brachial plexus, composed of contributions from the ventral rami of spinal nerves C5-C7. It provides motor innervation to the muscles in the anterior compartment of the upper arm: the coracobrachialis, biceps brachii, and brachialis. Additionally, it gives rise to the lateral antebrachial cutaneous nerve, which supplies sensory innervation to the skin on the lateral aspect of the forearm.

A nerve transfer is a surgical procedure where a functioning nerve is connected to an injured nerve to restore movement, sensation or function. The functioning nerve, called the donor nerve, usually comes from another less critical location in the body and has spare nerve fibers that can be used to reinnervate the injured nerve, called the recipient nerve.

During the procedure, a small section of the donor nerve is carefully dissected and prepared for transfer. The recipient nerve is also prepared by removing any damaged or non-functioning portions. The two ends are then connected using microsurgical techniques under a microscope. Over time, the nerve fibers from the donor nerve grow along the recipient nerve and reinnervate the muscles or sensory structures that were previously innervated by the injured nerve.

Nerve transfers can be used to treat various types of nerve injuries, including brachial plexus injuries, facial nerve palsy, and peripheral nerve injuries. The goal of the procedure is to restore function as quickly and efficiently as possible, allowing for a faster recovery and improved quality of life for the patient.

Peripheral Nervous System (PNS) diseases, also known as Peripheral Neuropathies, refer to conditions that affect the functioning of the peripheral nervous system, which includes all the nerves outside the brain and spinal cord. These nerves transmit signals between the central nervous system (CNS) and the rest of the body, controlling sensations, movements, and automatic functions such as heart rate and digestion.

PNS diseases can be caused by various factors, including genetics, infections, toxins, metabolic disorders, trauma, or autoimmune conditions. The symptoms of PNS diseases depend on the type and extent of nerve damage but often include:

1. Numbness, tingling, or pain in the hands and feet
2. Muscle weakness or cramps
3. Loss of reflexes
4. Decreased sensation to touch, temperature, or vibration
5. Coordination problems and difficulty with balance
6. Sexual dysfunction
7. Digestive issues, such as constipation or diarrhea
8. Dizziness or fainting due to changes in blood pressure

Examples of PNS diseases include Guillain-Barre syndrome, Charcot-Marie-Tooth disease, diabetic neuropathy, and peripheral nerve injuries. Treatment for these conditions varies depending on the underlying cause but may involve medications, physical therapy, lifestyle changes, or surgery.

The cervical plexus is a network of nerves that arises from the ventral rami (anterior divisions) of the first four cervical spinal nerves (C1-C4) and a portion of C5. These nerves form a series of loops and anastomoses (connections) that give rise to several major and minor branches.

The main functions of the cervical plexus include providing sensory innervation to the skin on the neck, shoulder, and back of the head, as well as supplying motor innervation to some of the muscles in the neck and shoulders, such as the sternocleidomastoid and trapezius.

Some of the major branches of the cervical plexus include:

* The lesser occipital nerve (C2), which provides sensory innervation to the skin over the back of the head and neck.
* The great auricular nerve (C2-C3), which provides sensory innervation to the skin over the ear and lower part of the face.
* The transverse cervical nerve (C2-C3), which provides sensory innervation to the skin over the anterior and lateral neck.
* The supraclavicular nerves (C3-C4), which provide sensory innervation to the skin over the shoulder and upper chest.
* The phrenic nerve (C3-C5), which supplies motor innervation to the diaphragm, the major muscle of respiration.

Overall, the cervical plexus plays a crucial role in providing sensory and motor innervation to the neck, head, and shoulders, allowing for normal movement and sensation in these areas.

Paralysis is a loss of muscle function in part or all of your body. It can be localized, affecting only one specific area, or generalized, impacting multiple areas or even the entire body. Paralysis often occurs when something goes wrong with the way messages pass between your brain and muscles. In most cases, paralysis is caused by damage to the nervous system, especially the spinal cord. Other causes include stroke, trauma, infections, and various neurological disorders.

It's important to note that paralysis doesn't always mean a total loss of movement or feeling. Sometimes, it may just cause weakness or numbness in the affected area. The severity and extent of paralysis depend on the underlying cause and the location of the damage in the nervous system.

The myenteric plexus, also known as Auerbach's plexus, is a component of the enteric nervous system located in the wall of the gastrointestinal tract. It is a network of nerve cells (neurons) and supporting cells (neuroglia) that lies between the inner circular layer and outer longitudinal muscle layers of the digestive system's muscularis externa.

The myenteric plexus plays a crucial role in controlling gastrointestinal motility, secretion, and blood flow, primarily through its intrinsic nerve circuits called reflex arcs. These reflex arcs regulate peristalsis (the coordinated muscle contractions that move food through the digestive tract) and segmentation (localized contractions that mix and churn the contents within a specific region of the gut).

Additionally, the myenteric plexus receives input from both the sympathetic and parasympathetic divisions of the autonomic nervous system, allowing for central nervous system regulation of gastrointestinal functions. Dysfunction in the myenteric plexus has been implicated in various gastrointestinal disorders, such as irritable bowel syndrome, achalasia, and intestinal pseudo-obstruction.

Intercostal nerves are the bundles of nerve fibers that originate from the thoracic spinal cord (T1 to T11) and provide sensory and motor innervation to the thorax, abdomen, and walls of the chest. They run between the ribs (intercostal spaces), hence the name intercostal nerves.

Each intercostal nerve has two components:

1. The lateral cutaneous branch: This branch provides sensory innervation to the skin on the side of the chest wall and abdomen.
2. The anterior cutaneous branch: This branch provides sensory innervation to the skin on the front of the chest and abdomen.

Additionally, each intercostal nerve also gives off a muscular branch that supplies motor innervation to the intercostal muscles (the muscles between the ribs) and the upper abdominal wall muscles. The lowest intercostal nerve (T11) also provides sensory innervation to a small area of skin over the buttock.

Intercostal nerves are important in clinical practice, as they can be affected by various conditions such as herpes zoster (shingles), rib fractures, or thoracic outlet syndrome, leading to pain and sensory changes in the chest wall.

Thoracic outlet syndrome (TOS) is a group of disorders that occur when the blood vessels or nerves in the thoracic outlet, the space between the collarbone (clavicle) and the first rib, become compressed. This compression can cause pain, numbness, and weakness in the neck, shoulder, arm, and hand.

There are three types of TOS:

1. Neurogenic TOS: This is the most common type and occurs when the nerves (brachial plexus) that pass through the thoracic outlet become compressed, causing symptoms such as pain, numbness, tingling, and weakness in the arm and hand.
2. Venous TOS: This type occurs when the veins that pass through the thoracic outlet become compressed, leading to swelling, pain, and discoloration of the arm.
3. Arterial TOS: This is the least common type and occurs when the arteries that pass through the thoracic outlet become compressed, causing decreased blood flow to the arm, which can result in pain, numbness, and coldness in the arm and hand.

TOS can be caused by a variety of factors, including an extra rib (cervical rib), muscle tightness or spasm, poor posture, repetitive motions, trauma, or tumors. Treatment for TOS may include physical therapy, pain management, and in some cases, surgery.

The shoulder joint, also known as the glenohumeral joint, is the most mobile joint in the human body. It is a ball and socket synovial joint that connects the head of the humerus (upper arm bone) to the glenoid cavity of the scapula (shoulder blade). The shoulder joint allows for a wide range of movements including flexion, extension, abduction, adduction, internal rotation, and external rotation. It is surrounded by a group of muscles and tendons known as the rotator cuff that provide stability and enable smooth movement of the joint.

Raikin S, Froimson MI (1997). "Bilateral brachial plexus compressive neuropathy (crutch palsy)". J Orthop Trauma. 11 (2): 136- ... Neuropathy in the hands and/or arms in patients with rheumatoid arthritis may in rare cases cause wrist drop. "When a joint ... to the chest at or below the clavicle-The radial nerve is the terminal branch of the posterior cord of the brachial plexus. A ... Radial neuropathy Dedeken P, Louw V, Vandooren AK, Verstegen G, Goossens W, Dubois B (June 2006). "Plumbism or lead ...
Raikin, Steven; Froimson, Mark I. (February 1997). "Bilateral Brachial Plexus Compressive Neuropathy (Crutch Palsy)". Journal ... Brachial plexus injury Unnava, Partha (2017-08-24). "Why it's important for crutches not to touch your armpits". Medium. ... Crutch paralysis is a form of paralysis which can occur when either the radial nerve or part of the brachial plexus, containing ...
"Kiloh-Nevin syndrome: a compression neuropathy or brachial plexus neuritis?." Acta Orthopaedica Belgica 73, no. 3 (June 2007): ... In brachial plexus neuritis, conservative management may be more appropriate. Spontaneous recovery has been reported, but is ... such as brachial plexus neuritis.⁠ Anterior interosseous nerve entrapment or compression injury remains a difficult clinical ... "Sonography of entrapment neuropathies in the upper limb (wrist excluded)." Journal of Clinical Ultrasound: JCU 32, no. 9: 438- ...
Beghi E, Kurland LT, Mulder DW, Nicolosi A (1985). "Brachial plexus neuropathy in the population of Rochester, Minnesota, 1970- ... "NINDS Brachial Plexus Injuries: Information Page". National Institute of Neurological Disorders and Stroke. September 29, 2008 ... Parsonage-Turner syndrome, also known as acute brachial neuropathy, neuralgic amyotrophy and abbreviated PTS, is a syndrome of ... For instance, a six-year-old could have brachial neuritis for only around six months, but a person in their early 50s could ...
In 2009, Hansen was diagnosed with brachial plexus neuropathy, a rare condition causing pain, weakness, and numbness in the ...
Brachial Plexus Lesions", Peripheral Neuropathy (Fourth Edition), Philadelphia: W.B. Saunders, pp. 1339-1373, doi:10.1016/b978- ... A brachial plexus nerve block can be achieved by injecting anaesthetic into this area. This article incorporates text in the ... The axillary sheath is a fibrous sheath that encloses the axillary artery and the three cords of the brachial plexus to form ...
... brachial neuritis Hereditary neuropathy with liability to pressure palsy Neonatal brachial plexus paralysis Neuropathy ... syringomyelia and tumors of the cervical cord or brachial plexus may be the cause. The onset of brachial plexus paralysis is ... Fever is often the first symptom of lumbar plexus paralysis, followed by pain in one or both legs. The pain has an abrupt onset ... Monoplegia of the upper limb is sometimes referred to as brachial monoplegia, and that of the lower limb is called crural ...
It could also be due to brachial plexus compression. The mechanism of radial neuropathy is such that it can cause focal ... Radial neuropathy is a type of mononeuropathy which results from acute trauma to the radial nerve that extends the length of ... Crutch paralysis Peripheral neuropathy Han, Bo Ram; Cho, Yong Jun; Yang, Jin Seo; Kang, Suk Hyung; Choi, Hyuk Jai (1 March 2014 ... Symptoms of radial neuropathy vary depending on the severity of the trauma; however, common symptoms may include wrist drop, ...
... amyloid neuropathies, familial MeSH C10.668.829.100 - brachial plexus neuropathies MeSH C10.668.829.100.500 - brachial plexus ... peroneal neuropathies MeSH C10.668.829.500.650 - radial neuropathy MeSH C10.668.829.500.675 - sciatic neuropathy MeSH C10.668. ... brachial plexus neuritis MeSH C10.668.829.650.500 - neuritis, autoimmune, experimental MeSH C10.668.829.675 - neurofibromatosis ... femoral neuropathy MeSH C10.668.829.500.500 - median neuropathy MeSH C10.668.829.500.500.200 - carpal tunnel syndrome MeSH ...
Of all brachial plexus injuries, axillary nerve palsy represents only .3% to 6% of them. Axillary nerve palsy patients present ... Since this is a problem with just one nerve, it is a type of Peripheral neuropathy called mononeuropathy. ... The axillary nerve comes from the posterior cord of the brachial plexus at the coracoid process and provides the motor function ...
Studies on RIBP have observed the brachial plexus' radiosensitivity. Injury was observed after dosages of 40 Gy in 20 fractions ... As of 1977 lumbosacral neuropathy arising from radiation therapy had been rarely reported. One of the earliest cases was in ... The lumbosacral plexus area is radiosensitive and radiation plexopathy can occur after exposure to mean or maximum radiation ... One method to reduce the lumbosacral plexus' dosing is to include it with other at-risk organs that get spared from radiation. ...
Brachial plexus Brachial plexus with courses of spinal nerves shown Long thoracic nerve at the Duke University Health System's ... Proximal Neuropathies of the Shoulder and Arm", Electromyography and Neuromuscular Disorders (Third Edition), London: W.B. ... It is posterior to the brachial plexus, and the axillary artery and vein. This takes it deep to the clavicle. It rests on the ... 487-500, doi:10.1016/b978-1-4557-2672-1.00031-3, ISBN 978-1-4557-2672-1, retrieved October 25, 2020 The right brachial plexus ( ...
Dejerine-Klumpke paralysis: Lower brachial plexus paralysis occurring during birth, particularly with breech deliveries; this ... A slowly progressive hereditary form of hypertrophic neuropathy characterised by motor and sensory disturbance in the limbs ...
Back pain Behçet's disease Bell's palsy Bipolar disorder Blindsight Blindness Blurred vision Brain damage Brachial plexus ... Diabetic neuropathy Disc herniation Diffuse sclerosis Diplopia Disorders of consciousness Distal hereditary motor neuropathy ... see Amyotrophic lateral sclerosis Motor skills disorder Moyamoya disease Mucopolysaccharidoses Multifocal motor neuropathy ... Coffin-Lowry syndrome Coma Complex post-traumatic stress disorder Complex regional pain syndrome Compression neuropathy ...
In the PNS, injury to the plexus nerves presents as radiation-induced brachial plexopathy or radiation-induced lumbosacral ... Depending upon the irradiated zone, late effect neuropathy may occur in either the central nervous system (CNS) or the ... Delanian S, Lefaix JL, Pradat PF (December 2012). "Radiation-induced neuropathy in cancer survivors". Radiotherapy and Oncology ...
It is increasingly important for brachial plexus imaging and for the diagnosis of thoracic outlet syndrome. Research and ... "MR imaging of entrapment neuropathies of the lower extremity: Part1. The pelvis and hip". RadioGraphics. 30 (4): 983-1000. doi: ... Zhou L, Yousem DM, Chaudhry V (September 2004). "Role of magnetic resonance neurography in brachial plexus lesions". Muscle ... the brachial plexus nerves (e.g. thoracic outlet syndrome), the pudendal nerve, or virtually any named nerve in the body. A ...
Practical Management of Pediatric and Adult Brachial Plexus Palsies, Philadelphia: W.B. Saunders, pp. 173-197, doi:10.1016/b978 ... Entrapment neuropathies and compartment syndromes", Rheumatology (Sixth Edition), Philadelphia: Content Repository Only!, pp. ...
... and deafferentation and somatic pain such as in phantom limb or brachial plexus injury (Boccard et al. 2013). The use of ... PNS is most effective in the treatment of neuropathic pain (e.g., posttraumatic neuropathy, diabetic neuropathy) when the nerve ... HWT has not been shown effective in reducing pain in cases other than diabetic neuropathy, nor has it been shown effective in ... It has been used in the treatment of pain related to diabetic neuropathy, muscle sprains, temporomandibular joint disorders, ...
One complication of shoulder dystocia is damage to the upper brachial plexus nerves. These supply the sensory and motor ... Perineal lacerations that extend into the anal sphincter Pubic symphysis separation Neuropathy of lateral femoral cutaneous ... Complications for the baby may include brachial plexus injury, or clavicle fracture. Complications for the mother may include ...
From the brachial plexus, it travels behind the third part of the axillary artery (part of the axillary artery distal to the ... Dorsal antibrachial cutaneous nerve Superficial branch of the radial nerve Deep branch of the radial nerve Radial neuropathy ... It originates from the brachial plexus, carrying fibers from the posterior roots of spinal nerves C5, C6, C7, C8 and T1. The ... The radial nerve originates as a terminal branch of the posterior cord of the brachial plexus. It goes through the arm, first ...
It is formed in the axilla by a branch from the medial and lateral chords of the brachial plexus, which are on either side of ... It may also occur from blunt force trauma or neuropathy. Median nerve palsy can be separated into 2 subsections-high and low ... AINS is considered as an extremely rare condition because it accounts for less than 1% of neuropathies in the upper limb. ... Hartz, CR; Linscheid, RL; Gramse, RR; Daube, JR (1981). "The pronator teres syndrome: compressive neuropathy of the median ...
Chung JH, Jeong SH, Dhong ES, Han SK (2014). "Surgical removal of intraneural perineurioma arising in the brachial plexus using ... focal hypertrophic neuropathy of youth". Brain. 132 (Pt 8): 2265-2276. doi:10.1093/brain/awp169. PMC 2724918. PMID 19567701. ...
... nerve palsies 352.9 Unspecified 353 Nerve root and plexus disorders 353.0 Brachial plexus lesions 353.1 Lumbosacral plexus ... neuropathy 356.0 Hereditary peripheral neuropathy 356.1 Peroneal muscular atrophy 356.2 Hereditary sensory neuropathy 356.3 ... Peripheral autonomic neuropathy in disorders classified elsewhere 337.9 Unspecified 340 Multiple sclerosis 341 Other ... diseases of spinal cord 337 Disorders of the autonomic nervous system 337.0 Idiopathic peripheral autonomic neuropathy 337.1* ...
... of the brachial plexus) Plan of the cervical plexus. The nerves of the scalp, face, and side of neck. The right sympathetic ... "Neuropathies, Iatrogenic", in Aminoff, Michael J.; Daroff, Robert B. (eds.), Encyclopedia of the Neurological Sciences (Second ... The cervical plexus is a nerve plexus of the anterior rami of the first (i.e. upper-most) four cervical spinal nerves C1-C4. ... The cervical plexus provides motor innervation to some muscles of the neck, and the diaphragm; it provides sensory innervation ...
Nerves Brachial plexus (shoulder), ulnar nerve (elbow/hand), peroneal nerve (ankle/foot), cranial nerves I-XII(head) Bones ... Electrodiagnosis also helps differentiate between myopathy and neuropathy. Using the RICE method can somewhat be controversial ...
... Brachial plexus with characteristic M, ulnar nerve labeled. Ulnar nerve Ulnar nerve Ulnar nerve Brachial plexus. ... Entrapment Neuropathies", Essentials of Pain Medicine and Regional Anesthesia (Second Edition), Philadelphia: Churchill ... which then form part of the medial cord of the brachial plexus, and descends medial to the brachial artery, up until the ... Brachial plexus with courses of spinal nerves shown Cross-section through the middle of upper arm. Cross-section through the ...
These three nerves branch off the posterior cord of the brachial plexus. The nerves that innervate teres major consist of ... Compression and entrapment neuropathies", Handbook of Clinical Neurology, Peripheral Nerve Disorders, Elsevier, 115: 311-366, ...
... brachial plexopathy - brachial plexus - brachytherapy - brain metastasis - brainstem glioma - brain stem tumor - brain tumor - ... chemotherapy-induced peripheral neuropathy - chest x-ray - chiasma - child-life worker - chitin - chlorambucil - chlorine - ... choroid plexus tumor - CHPP - chronic granulocytic leukemia - chronic idiopathic myelofibrosis - chronic leukemia - chronic ... peripheral neuropathy - peripheral primitive neuroectodermal tumor - peripheral stem cell - peripheral stem cell support - ...
A claw hand can result of injuries to the inferior brachial plexus (C8-T1). The condition may arise from the limb being ... It is linked to palsy, which is a result of peripheral neuropathy. There is a range of ways that damage to the nerve can occur ...
... compression by pectoralis minor muscles Brachial plexus abnormalities Elbow: fractures, growth plate injuries, cubital tunnel ... Symptoms of ulnar neuropathy may be motor, sensory, or both depending on the location of injury. Motor symptoms consistent of ... Symptoms of ulnar neuropathy or neuritis do not necessarily indicate an actual physical impingement of the nerve; any injury to ... In general, ulnar neuropathy will result in symptoms in a specific anatomic distribution, affecting the little finger, the ...

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