A diffuse, non-pitting induration of the skin of unknown etiology that occurs most commonly in association with diabetes mellitus, predominantly in females. It typically begins on the face or head and spreads to other areas of the body, sometimes involving noncutaneous tissues. Often it is preceded by any of various infections, notably staphylococcal infections. The condition resolves spontaneously, usually within two years of onset. (From Dorland, 27th ed)
A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
The total amount (cell number, weight, size or volume) of tumor cells or tissue in the body.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
A cell line derived from cultured tumor cells.
A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.
Sexually transmitted form of anogenital warty growth caused by the human papillomaviruses.
Pathological processes of the VULVA.
Benign epidermal proliferations or tumors; some are viral in origin.
A plant genus of the family NYSSACEAE (sometimes classified in the CORNACEAE family). It is a source of CAMPTOTHECIN.
A family of small, non-enveloped DNA viruses infecting birds and most mammals, especially humans. They are grouped into multiple genera, but the viruses are highly host-species specific and tissue-restricted. They are commonly divided into hundreds of papillomavirus "types", each with specific gene function and gene control regions, despite sequence homology. Human papillomaviruses are found in the genera ALPHAPAPILLOMAVIRUS; BETAPAPILLOMAVIRUS; GAMMAPAPILLOMAVIRUS; and MUPAPILLOMAVIRUS.
A plant genus of the family Musaceae, order Zingiberales, subclass Zingiberidae, class Liliopsida.
'Anus diseases' refer to various medical conditions affecting the anus, including structural abnormalities, inflammatory disorders, infections, and neoplasms, which can cause symptoms such as pain, bleeding, itching, or changes in bowel habits.

Buschke -Loewenstein tumor: identification of HPV type 6 and 11. (1/4)

 (+info)

Comprehensive analysis of human papillomavirus prevalence and the potential role of low-risk types in verrucous carcinoma. (2/4)

 (+info)

Buschke-Lowenstein Tumor. (3/4)

INTRODUCTION: Giant condyloma acuminatum belongs to a spectrum of diseases with malignant degeneration. Clinically, it presents as exophytic, fungating masses, sometimes with a cauliflower-like morphology. CASE PRESENTATION: We present a case of a 32-year-old female patient with a 180x95x80mm exophytic mass of the vulvar region suggestive of Buschke-Lowenstein Tumour. Treatment included wide local excision with electrosurgery and CO2 vaporization of recurrent focal lesions. Histopathological analysis confirmed the expected diagnosis. Surgery went without complications and the patient is lesion-free at the 12th month of follow-up. CONCLUSION: There is a lack of consistent trials regarding optimal treatment of BLT. Surgery, when feasible, remains the mainstay of treatment. It allows quick lesion size reduction, with fewer side effects and more rapid return to daily living activities, when compared to other treatment options.  (+info)

Buschke-Lowenstein tumor with squamous cell carcinoma treated with chemo-radiation therapy and local surgical excision: report of three cases. (4/4)

 (+info)

Scleredema Adultorum is a rare and chronic connective tissue disorder, primarily characterized by thickening and hardening (induration) of the skin. The term "adultorum" refers to its occurrence in adults, although similar conditions can affect children.

The key features of Scleredema Adultorum include:

1. Skin induration: Thickening and hardening of the skin, often starting on the neck and upper back, before spreading to other areas such as the chest, abdomen, and extremities. The overlying skin may appear normal or have a woody texture.
2. Progression: The condition typically progresses in three stages - early, intermediate, and late. In the early stage, symptoms are usually limited to the skin. As the disease advances, it can affect deeper tissues, including muscles and nerves.
3. Associations: Scleredema Adultorum is often associated with certain medical conditions, such as diabetes mellitus, monoclonal gammopathy (abnormal proliferation of a single clone of plasma cells), and following infections like streptococcus.

The exact cause of Scleredema Adultorum remains unclear; however, it is believed to involve abnormalities in collagen metabolism and excessive deposition of extracellular matrix components, such as glycosaminoglycans, in the skin and underlying tissues. Treatment options are limited, and the prognosis varies depending on the severity and progression of the disease.

'Mycobacterium tuberculosis' is a species of slow-growing, aerobic, gram-positive bacteria that demonstrates acid-fastness. It is the primary causative agent of tuberculosis (TB) in humans. This bacterium has a complex cell wall rich in lipids, including mycolic acids, which provides a hydrophobic barrier and makes it resistant to many conventional antibiotics. The ability of M. tuberculosis to survive within host macrophages and resist the immune response contributes to its pathogenicity and the difficulty in treating TB infections.

M. tuberculosis is typically transmitted through inhalation of infectious droplets containing the bacteria, which primarily targets the lungs but can spread to other parts of the body (extrapulmonary TB). The infection may result in a spectrum of clinical manifestations, ranging from latent TB infection (LTBI) to active disease. LTBI represents a dormant state where individuals are infected with M. tuberculosis but do not show symptoms and cannot transmit the bacteria. However, they remain at risk of developing active TB throughout their lifetime, especially if their immune system becomes compromised.

Effective prevention and control strategies for TB rely on early detection, treatment, and public health interventions to limit transmission. The current first-line treatments for drug-susceptible TB include a combination of isoniazid, rifampin, ethambutol, and pyrazinamide for at least six months. Multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of M. tuberculosis present significant challenges in TB control and require more complex treatment regimens.

Tumor markers are substances that can be found in the body and their presence can indicate the presence of certain types of cancer or other conditions. Biological tumor markers refer to those substances that are produced by cancer cells or by other cells in response to cancer or certain benign (non-cancerous) conditions. These markers can be found in various bodily fluids such as blood, urine, or tissue samples.

Examples of biological tumor markers include:

1. Proteins: Some tumor markers are proteins that are produced by cancer cells or by other cells in response to the presence of cancer. For example, prostate-specific antigen (PSA) is a protein produced by normal prostate cells and in higher amounts by prostate cancer cells.
2. Genetic material: Tumor markers can also include genetic material such as DNA, RNA, or microRNA that are shed by cancer cells into bodily fluids. For example, circulating tumor DNA (ctDNA) is genetic material from cancer cells that can be found in the bloodstream.
3. Metabolites: Tumor markers can also include metabolic products produced by cancer cells or by other cells in response to cancer. For example, lactate dehydrogenase (LDH) is an enzyme that is released into the bloodstream when cancer cells break down glucose for energy.

It's important to note that tumor markers are not specific to cancer and can be elevated in non-cancerous conditions as well. Therefore, they should not be used alone to diagnose cancer but rather as a tool in conjunction with other diagnostic tests and clinical evaluations.

Tumor burden is a term used to describe the total amount of cancer in the body. It can refer to the number of tumors, the size of the tumors, or the amount of cancer cells in the body. In research and clinical trials, tumor burden is often measured to assess the effectiveness of treatments or to monitor disease progression. High tumor burden can cause various symptoms and complications, depending on the type and location of the cancer. It can also affect a person's prognosis and treatment options.

Tumor Necrosis Factor-alpha (TNF-α) is a cytokine, a type of small signaling protein involved in immune response and inflammation. It is primarily produced by activated macrophages, although other cell types such as T-cells, natural killer cells, and mast cells can also produce it.

TNF-α plays a crucial role in the body's defense against infection and tissue injury by mediating inflammatory responses, activating immune cells, and inducing apoptosis (programmed cell death) in certain types of cells. It does this by binding to its receptors, TNFR1 and TNFR2, which are found on the surface of many cell types.

In addition to its role in the immune response, TNF-α has been implicated in the pathogenesis of several diseases, including autoimmune disorders such as rheumatoid arthritis, inflammatory bowel disease, and psoriasis, as well as cancer, where it can promote tumor growth and metastasis.

Therapeutic agents that target TNF-α, such as infliximab, adalimumab, and etanercept, have been developed to treat these conditions. However, these drugs can also increase the risk of infections and other side effects, so their use must be carefully monitored.

A cell line that is derived from tumor cells and has been adapted to grow in culture. These cell lines are often used in research to study the characteristics of cancer cells, including their growth patterns, genetic changes, and responses to various treatments. They can be established from many different types of tumors, such as carcinomas, sarcomas, and leukemias. Once established, these cell lines can be grown and maintained indefinitely in the laboratory, allowing researchers to conduct experiments and studies that would not be feasible using primary tumor cells. It is important to note that tumor cell lines may not always accurately represent the behavior of the original tumor, as they can undergo genetic changes during their time in culture.

Wilms tumor, also known as nephroblastoma, is a type of kidney cancer that primarily affects children. It occurs in the cells of the developing kidneys and is named after Dr. Max Wilms, who first described this type of tumor in 1899. Wilms tumor typically develops before the age of 5, with most cases occurring in children under the age of 3.

The medical definition of Wilms tumor is:

A malignant, embryonal kidney tumor originating from the metanephric blastema, which is a mass of undifferentiated cells in the developing kidney. Wilms tumor is characterized by its rapid growth and potential for spread (metastasis) to other parts of the body, particularly the lungs and liver. The tumor usually presents as a large, firm, and irregular mass in the abdomen, and it may be associated with various symptoms such as abdominal pain, swelling, or blood in the urine.

Wilms tumor is typically treated with a combination of surgery, chemotherapy, and radiation therapy. The prognosis for children with Wilms tumor has improved significantly over the past few decades due to advances in treatment methods and early detection.

'Condylomata Acuminata' is the medical term for genital warts, which are growths or bumps that appear on the genital area. They are caused by certain types of the human papillomavirus (HPV). Genital warts can vary in appearance, and they may be small, flat, and difficult to see or large, cauliflower-like, and easily visible.

The warts can appear on the vulva, vagina, cervix, rectum, anus, penis, or scrotum. They are usually painless but can cause discomfort during sexual intercourse. In some cases, genital warts can lead to serious health problems, such as cervical cancer in women.

It is important to note that not all people with HPV will develop genital warts, and many people with HPV are asymptomatic and unaware they have the virus. The Centers for Disease Control and Prevention (CDC) recommends routine HPV vaccination for both boys and girls aged 11-12 years to prevent HPV infection and related diseases, including genital warts.

Vulvar diseases refer to a range of medical conditions that affect the vulva, which is the external female genital area including the mons pubis, labia majora and minora, clitoris, and the vaginal opening. These conditions can cause various symptoms such as itching, burning, pain, soreness, irritation, or abnormal growths or lesions. Some common vulvar diseases include:

1. Vulvitis: inflammation of the vulva that can be caused by infection, allergies, or irritants.
2. Lichen sclerosus: a chronic skin condition that causes thin, white patches on the vulva.
3. Lichen planus: an inflammatory condition that affects the skin and mucous membranes, including the vulva.
4. Vulvar cancer: a rare type of cancer that develops in the tissues of the vulva.
5. Genital warts: caused by human papillomavirus (HPV) infection, these are small growths or bumps on the vulva.
6. Pudendal neuralgia: a nerve condition that causes pain in the vulvar area.
7. Vestibulodynia: pain or discomfort in the vestibule, the area surrounding the vaginal opening.

It is important to consult a healthcare professional if experiencing any symptoms related to vulvar diseases for proper diagnosis and treatment.

Warts are small, rough growths on the skin or mucous membranes caused by one of several types of human papillomavirus (HPV). They can appear anywhere on the body but most often occur on the hands, fingers, and feet. Warts are benign, non-cancerous growths, but they can be unsightly, uncomfortable, or painful, depending on their location and size.

Warts are caused by HPV infecting the top layer of skin, usually through a small cut or scratch. The virus triggers an overproduction of keratin, a protein in the skin, leading to the formation of a hard, rough growth. Warts can vary in appearance depending on their location and type, but they are generally round or irregularly shaped, with a rough surface that may be flat or slightly raised. They may also contain small black dots, which are actually tiny blood vessels that have clotted.

Warts are contagious and can spread from person to person through direct skin-to-skin contact or by sharing personal items such as towels or razors. They can also be spread by touching a wart and then touching another part of the body. Warts may take several months to develop after exposure to HPV, so it may not always be clear when or how they were contracted.

There are several types of warts, including common warts, plantar warts (which occur on the soles of the feet), flat warts (which are smaller and smoother than other types of warts), and genital warts (which are sexually transmitted). While most warts are harmless and will eventually go away on their own, some may require medical treatment if they are causing discomfort or are unsightly. Treatment options for warts include topical medications, cryotherapy (freezing the wart with liquid nitrogen), and surgical removal.

Camptotheca is a genus of trees in the family Nyssaceae, native to China and Tibet. It is also known as "camptotheca acuminata" or "the Chinese happy tree." The bark and leaves of this tree contain camptothecin, a compound that has been studied for its potential anti-cancer properties. Camptothecin and its derivatives are used in the treatment of various types of cancer, including colon, ovarian, and small cell lung cancer.

Papillomaviridae is a family of small, non-enveloped DNA viruses that primarily infect the epithelial cells of mammals, birds, and reptiles. The name "papillomavirus" comes from the Latin word "papilla," which means nipple or small projection, reflecting the characteristic wart-like growths (papillomas) that these viruses can cause in infected host tissues.

The family Papillomaviridae includes more than 200 distinct papillomavirus types, with each type being defined by its specific DNA sequence. Human papillomaviruses (HPVs), which are the most well-studied members of this family, are associated with a range of diseases, from benign warts and lesions to malignant cancers such as cervical, anal, penile, vulvar, and oropharyngeal cancers.

Papillomaviruses have a circular, double-stranded DNA genome that is approximately 8 kbp in size. The viral genome encodes several early (E) proteins involved in viral replication and oncogenesis, as well as late (L) proteins that form the viral capsid. The life cycle of papillomaviruses is tightly linked to the differentiation program of their host epithelial cells, with productive infection occurring primarily in the differentiated layers of the epithelium.

In summary, Papillomaviridae is a family of DNA viruses that infect epithelial cells and can cause a variety of benign and malignant diseases. Human papillomaviruses are a significant public health concern due to their association with several cancer types.

"Musa" is the genus name for bananas and plantains in the botanical classification system. It belongs to the family Musaceae and includes over 70 species of tropical herbaceous plants that are native to Southeast Asia. The fruit produced by these plants is also commonly referred to as "bananas" or "plantains," depending on the specific variety and its culinary use.

However, I believe you may have been looking for a medical term, and I apologize for any confusion. In that case, I should note that "Musa" is not a recognized medical term in English. If you have any further questions or need clarification on a different medical term, please let me know!

The anus is the opening at the end of the digestive tract where feces are eliminated from the body. There are several diseases and conditions that can affect the anus, including:

1. Anal fissure: A small tear in the lining of the anus, which can cause pain and bleeding during bowel movements.
2. Hemorrhoids: Swollen veins in the rectum or anus that can cause discomfort, itching, and bleeding.
3. Perianal abscess: A collection of pus in the tissue surrounding the anus, which can cause pain, swelling, and redness.
4. Anal fistula: An abnormal connection between the anal canal and the skin around the anus, often resulting from a perianal abscess that did not heal properly.
5. Anal cancer: A rare form of cancer that develops in the cells lining the anus, usually affecting people over the age of 50.
6. Inflammatory bowel disease (IBD): A group of chronic inflammatory conditions of the intestine, including Crohn's disease and ulcerative colitis, which can affect the anus and cause symptoms such as pain, bleeding, and diarrhea.
7. Sexually transmitted infections (STIs): Certain STIs, such as herpes simplex virus, chlamydia, gonorrhea, and syphilis, can affect the anus and cause symptoms such as pain, discharge, and sores.
8. Fecal incontinence: The involuntary loss of bowel control, which can be caused by nerve damage, muscle weakness, or other medical conditions affecting the anus.

Safi F, Bekdache O, Al-Salam S, Alashari M, Mazen T. Giant condyloma acuminatum of Buschke-Lowenstein tumour: disease ... Buschke-Löwensteoin tumors are frequently associated with HPV subtypes 6 and 11. Treatment involves surgical resection and ... Due to their size, these tumors can be locally invasive and destructive. Owing to their impressive growth patterns, Buschke- ... PMID 29644039 Venter F, Heidari A, Viehweg M, Rivera M, Natarajan P, Cobos E. Giant condylomata acuminata of Buschke-Lowenstein ...
... and Ludwig Lowenstein: Giant Condyloma (Buschke-Loewenstein)". The American Journal of Dermatopathology. 28 (6 ... Buschke-Löwenstein tumor: Also known as giant condyloma acuminatum; a variety of venereal wart characterized by its large, ... Abraham Buschke (27 September 1868 - 25 February 1943) was a Jewish German dermatologist who was a native of Nakel in the ... Abraham Buschke specialized in research of venereal disease. In 1926 with Martin Gumpert (1897-1955) he published a treatise on ...
... the giant condyloma of Buschke and Löwenstein (GCBL) is a slow-growing, locally destructive verrucous plaque that typically ... Buschke-Lowenstein tumor successful treatment by surgical excision alone: a case report. Surg Innov. 2006 Mar. 13(1):69-72. [ ... Giant Condylomata Acuminata of Buschke and Lowenstein) and Giant Condylomata Acuminata of Buschke and Lowenstein What to Read ... Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions. Analysis of 42 cases. Dis Colon ...
Buschke-Lowenstein tumor in a woman living with HIV/AIDS Images In Infectious Diseases. Araújo, Paulo Sérgio Ramos de; Padilha ... This report describes a case of HL in a 14-year-old Brazilian boy, who presented with multiple nodular and tumor-like lesions, ... using the proportion method with Lowenstein-Jensen medium or the BACTEC MGIT 960 system. RESULTS: The detection accuracy for ...
Giant condyloma acuminatum (Buschke-Lowenstein tumor). Beltrán Pérez, Ibis; Reyes Argudín, Miguel A; Navarro Garvey, Yoel; ... Mortality from malignant brain tumors within the first 30 days after surgery. Solomon Cardona, María Teresa; Roig Fabre, ...
Safi F, Bekdache O, Al-Salam S, Alashari M, Mazen T. Giant condyloma acuminatum of Buschke-Lowenstein tumour: disease ... Buschke-Löwensteoin tumors are frequently associated with HPV subtypes 6 and 11. Treatment involves surgical resection and ... Due to their size, these tumors can be locally invasive and destructive. Owing to their impressive growth patterns, Buschke- ... PMID 29644039 Venter F, Heidari A, Viehweg M, Rivera M, Natarajan P, Cobos E. Giant condylomata acuminata of Buschke-Lowenstein ...
... the giant condyloma of Buschke and Löwenstein (GCBL) is a slow-growing, locally destructive verrucous plaque that typically ... Buschke-Lowenstein tumor successful treatment by surgical excision alone: a case report. Surg Innov. 2006 Mar. 13(1):69-72. [ ... Giant Condylomata Acuminata of Buschke and Lowenstein) and Giant Condylomata Acuminata of Buschke and Lowenstein What to Read ... Crespo R, Puig F, Lanzon A, Borell A. Buschke-Lowenstein tumor and pregnancy: a case report. Eur J Gynaecol Oncol. 2007. 28(4): ...
Also called Buschke-Löwenstein tumor *Also called verrucous carcinoma by some authors but most authors consider them to be ... Giant Condylomata Acuminata of Buschke and Lowenstein [Accessed 2 April 2018]) ... Verrucous carcinoma: no koilocytosis, no prominent papillae with fibrovascular cores; pushing tumor base *Warty carcinoma: ... 5 - 10 cm cauliflower-like verruciform tumor with cobblestone surface *Cut surface shows papillomatous growth with sharp ...
The Buschke-Lowenstein tumor (BLT) is a slow-growing, locally destructive verrucous plaque that typically appears on the penis ... Successful Surgical Management of Giant Condyloma Acuminatum (Buschke Lowenstein Tumor) in the Urethra of a Female Patient: A ... It was first described by Buschke and Löwenstein in 1925, and is also known as giant condyloma acuminatum (GCA). Regardless of ...
Verrucous carcinoma of the anus or Buschke-Lowenstein tumor of the anus: staging and treatment. Report of 3 cases] 2005 ... Verrucous carcinoma of the anus or Buschke-Lowenstein tumor of the anus: staging and treatment. Report of 3 cases]. ... A collection of primary tissue cultures of tumors from vacuum packed and cooled surgical specimens: a feasibility study 2013 ... AR/ER Ratio Correlates with Expression of Proliferation Markers and with Distinct Subset of Breast Tumors 2020 Rangel N.; ...
Buschke-Loewenstein tumor: verrucous carcinoma of the penis. J Am Acad Dermatol. 1990 Oct. 23(4 Pt 1):723-7. [QxMD MEDLINE Link ... Buschke A, Lowenstein L. Uber Carcinomahnliche Condylomata Acuminata des Penis. Klin Wochenschr. 1925. 4:1726-1728. ... Buschke-Löwenstein tumor: verrucous carcinoma of the anogenitalia. Cutis. 1991 Apr. 47(4):263-6. [QxMD MEDLINE Link]. ... Giant condyloma acuminatum of Buschke and Lowenstein. Demis DJ. Clinical Dermatology. 18th. Philadelphia, Pa: JB Lippincott; ...
Giant Condyloma of Buschke-Lowenstein: An Atypical Case An uncommonly aggressive case of giant condyloma of Buschke-Lowenstein ... When Brunner Glands Are Not So Innocent Two cases of Brunner gland tumors are reported in which both patients present with ... Challenges in Diagnosing Biliary Stricture Diagnosis and staging of biliary tumors is difficult despite advances in imaging ...
Buschke Lowenstein Tumor Whats New Last Posted: Jan 01, 2011 * Buschke Lowenstein tumor From NCATS Genetic and Rare Diseases ...
Buschke-Lowenstein tumor. Laboratory. Serologic test for syphilis - negative. Drugs that may alter lab results: N/A ...
J Am Acad e Dermatol ; Human Buschke-Lowenstein tumour of glans penis. Papillomavirus-Associated Cancers - united States, - ...
Buschke Lowenstein Tumor Symptoms, Causes, Radiology, Treatment. April 15, 2022. Plexiform Fibrohistiocytic Tumor Symptoms, ... is particularly indicated for patients whose tumors express a BRAF V600E mutation, the protein that helps melanoma tumors grow ...
Buschke-Lowenstein tumor: Use of dermal matrix for reconstruction of genital area.. Dermatol Ther. 2020 Jun 18:e13874. doi: ... Understanding tumor-stroma interplays for targeted therapies by armed mesenchymal stromal progenitors: the Mesenkillers.. Am J ...
Buschke-Lowenstein tumor more than other genital warts, located in the perianal area, tend to degenerate into malignant tumors ... Sometimes genital warts fuse together and grow to gigantic proportions (Buschke-Lowenstein tumor). The peculiarity of these ... confirmed diagnosis of warts and abnormal cells are detected characteristic of malignant tumors. If necessary, the PCR ...
... are associated with precancerous lesions like giant pointed condylomas or Buschke-Lowenstein tumors. These conditions have a ... These conditions are characterized by the appearance of papulo-tumor-like growths on the skin and mucous membranes. Here, we ...
Introducción: El tumor de Buschke - Lowenstein (TBL) es enfermedad de transmisión sexual causada por el virus del papiloma ... Tumor de Buschke - Löwenstein: Presentación de un Caso y Revisión Bibliográfica / Buschke - Löwenstein Tumor: A Case Report and ... Introduction: Buschke-Lowenstein tumor (BLT) is a sexually transmitted disease caused by the human papillomavirus (HPV), ... Humanos , Adulto , Condiloma Acuminado , Tumor de Buschke-Lowenstein , Radioterapia , Vacinas Combinadas , Papillomavirus ...
Buschke-Lowenstein tumour). Histopathology. 2017;70:938-945.. *Pitra T, Pivovar kov K, Sedl kov H, Hes O, Hora M, Daum O. Lynch ... Ferda J, Ferdova E, Zahlava J, Walter J, Mukensnabl P, Daum O, Kreuzberg B. 18F-FDG-PET/CT of orofacial tumors, a value of ... Familial gastrointestinal stromal tumor with germ line mutation of the juxtamembrane domain of the KIT gene observed in ... Daum O, Hes O, Vanecek T, Benes Z, Sima R, Zamecnik M, Mukensnabl P, Hadravska S, Curik R, Michal M. Vaneks tumor ( ...
Buschke-Lowenstein tumor, squamous cell carcinoma, and verrucous carcinoma 2 , 7 . For an accurate diagnosis, a deep biopsy ... described four stages of the evolution of PKMB; i) initial plaque stage, ii) late tumor stage, iii) verrucous carcinoma, and iv ...
Buschke-Loewenstein tumor: verrucous carcinoma of the penis. J Am Acad Dermatol. 1990 Oct. 23(4 Pt 1):723-7. [QxMD MEDLINE Link ... Buschke A, Lowenstein L. Uber Carcinomahnliche Condylomata Acuminata des Penis. Klin Wochenschr. 1925. 4:1726-1728. ... Buschke-Löwenstein tumor: verrucous carcinoma of the anogenitalia. Cutis. 1991 Apr. 47(4):263-6. [QxMD MEDLINE Link]. ... Giant condyloma acuminatum of Buschke and Lowenstein. Demis DJ. Clinical Dermatology. 18th. Philadelphia, Pa: JB Lippincott; ...
Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Linear IgA Bullous Dermatosis. Dermatose ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. C03 - Parasitic Diseases. ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Cystadenofibroma. Cistoadenofibroma. ...
Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Linear IgA Bullous Dermatosis. Dermatose ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. C03 - Parasitic Diseases. ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Cystadenofibroma. Cistoadenofibroma. ...
Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Linear IgA Bullous Dermatosis. Dermatose ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. C03 - Parasitic Diseases. ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Cystadenofibroma. Cistoadenofibroma. ...
Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Linear IgA Bullous Dermatosis. Dermatose ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. C03 - Parasitic Diseases. ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Cystadenofibroma. Cistoadenofibroma. ...
Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Linear IgA Bullous Dermatosis. Dermatose ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. C03 - Parasitic Diseases. ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Cystadenofibroma. Cistoadenofibroma. ...
Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Linear IgA Bullous Dermatosis. Dermatose ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. C03 - Parasitic Diseases. ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Cystadenofibroma. Cistoadenofibroma. ...
Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Linear IgA Bullous Dermatosis. Dermatose ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. C03 - Parasitic Diseases. ... Buschke-Lowenstein Tumor. Tumor de Buschke-Lowenstein. Tumor de Buschke-Lowenstein. Cystadenofibroma. Cistoadenofibroma. ...
... giant condyloma of Buschke and Lowenstein); when verrucous carcinoma involves the plantar surface of the foot, it is named ... Surgical intervention is the treatment of choice for CC, with a 5-mm tumor-free margin so that early detection may result in a ... giant condyloma of Buschke and Lowenstein); when verrucous carcinoma involves the plantar surface of the foot, it is named ... Surgical intervention is the treatment of choice for CC, with a 5-mm tumor-free margin so that early detection may result in a ...
  • Giant condyloma acuminatum (also known as a Buschke-Löwenstein tumor) is a rare cutaneous condition characterized by an aggressive, wart-like growth that is a verrucous carcinoma. (wikipedia.org)
  • Safi F, Bekdache O, Al-Salam S, Alashari M, Mazen T. Giant condyloma acuminatum of Buschke-Lowenstein tumour: disease development between 2000 and 2010. (wikipedia.org)
  • Giant anorectal condyloma acuminatum of Buschke-Löwenstein presents difficult management decisions. (wikipedia.org)
  • First described by Buschke and Löwenstein in 1925, the giant condyloma of Buschke and Löwenstein (GCBL) is a slow-growing, locally destructive verrucous plaque that typically appears on the penis but may occur elsewhere in the anogenital region. (medscape.com)
  • Verrucous carcinoma of the anus or Buschke-Lowenstein tumor of the anus: staging and treatment. (unito.it)
  • Oral, laryngeal, pharyngeal, and esophageal lesions of this type are generally known as a verrucous carcinoma or an Ackerman tumor. (medscape.com)
  • Although the term verrucous carcinoma followed by its anatomical site would be the most comprehensive name, the historical name justifiably favors honoring 2 eminent physicians, Abraham Buschke (1868-1943) of Berlin and Ackerman (1905-1993). (medscape.com)
  • Buschke was a legendary professor of dermatology, and Ackerman, the renowned professor of pathology, developed the concept of verrucous carcinoma. (medscape.com)
  • Verrucous carcinoma of both the skin and the mucosa is an uncommon low-grade squamous cell carcinoma that is clinically evident as a slowly but relentlessly enlarging warty tumor, histologically characterized by local invasion with minimal dysplasia, if any, and biologically characterized by a low incidence of metastases. (medscape.com)
  • Daum O, Grossmann P, Vanecek T, Sima R, Mukensnabl P, Michal M. Diagnostic morphological features of PDGFRA-mutated gastrointestinal stromal tumors: molecular genetic and histologic analysis of 60 cases of gastric gastrointestinal stromal tumors. (patologie.cz)
  • Daum O, Vanecek T, Benes Z, Michal M. Progress in molecular diagnostics of gastrointestinal stromal tumors. (patologie.cz)
  • C-Kit (CD117), Gastrointestinal Stromal Tumors (GISTs). (booksdo.com)
  • PMID 29644039 Venter F, Heidari A, Viehweg M, Rivera M, Natarajan P, Cobos E. Giant condylomata acuminata of Buschke-Lowenstein associated with paraneoplastic hypercalcemia. (wikipedia.org)
  • Wiedemann A, Diekmann WP, Holtmann G, Kracht H. Report of a case with giant condyloma (Buschke-Lowenstein tumor) localized in the bladder. (medscape.com)
  • Giant Condyloma of Buschke-Lowenstein: An Atypical Case An uncommonly aggressive case of giant condyloma of Buschke-Lowenstein is found in an atypical patient. (medscape.com)
  • Yes, low-risk HPV variants, particularly types 6 and 11, are associated with precancerous lesions like giant pointed condylomas or Buschke-Lowenstein tumors. (trustedtablets.online)
  • Daum O, Ferdova E, Kural T, Grossmann P, Nemcova J, Mukensnabl P, Michal M. Pancreatic undifferentiated carcinoma with osteoclast-like giant cells masquerading as (extra)gastrointestinal stromal tumor: potential diagnostic pitfall. (patologie.cz)
  • Results: Conjunctival papilloma is a benign squamous cell tumor of the conjunctiva with a minimal tendency to malignancy. (bvsalud.org)
  • When Brunner Glands Are Not So Innocent Two cases of Brunner gland tumors are reported in which both patients present with melena and anemia, but one case is benign and the other is malignant. (medscape.com)
  • Glansectomy: an alternative surgical treatment for Buschke-Lowenstein tumors of the penis. (nature.com)
  • Tumors of the penis. (wikipedia.org)
  • Fewer than 50 cases of perianal tumors and only 20-30 cases of vulvar or bladder GCBL have been reported. (medscape.com)
  • [ 6 ] The dependency of Buschke-Löwenstein tumor growth to a state of decreased immune responsiveness is exemplified by the development of new penile and perianal lesions in a male with chronic lymphocytic leukemia at the time he received chemotherapy. (medscape.com)
  • CT can show early, typical signs of an aggressive tumor, as radiolucent lesions with ill-defined margins and resorption of the adjacent cortical bone. (units.it)
  • The histopathological diagnosis was CC. Surgical intervention is the treatment of choice for CC, with a 5-mm tumor-free margin so that early detection may result in a smaller surgical defect. (units.it)
  • In other words, it delineates the depth of involvement of tumor but does not influence the final choice of surgical procedure in an early stage of invasion. (units.it)
  • Due to their size, these tumors can be locally invasive and destructive. (wikipedia.org)
  • Accuracy of tumour size assessment in the preoperative staging of breast cancer: comparison of digital mammography, tomosynthesis, ultrasound and MRI. (unito.it)
  • Owing to their impressive growth patterns, Buschke-Löwenstein tumors displace and destroy adjacent structures from compression. (wikipedia.org)
  • Zelboraf (Vemurafenib) is particularly indicated for patients whose tumors express a BRAF V600E mutation, the protein that helps melanoma tumors grow. (cancerworld.info)
  • Daum O, Klecka J, Ferda J, Treska V, Vanecek T, Sima R, Mukensnabl P, Michal M. Gastrointestinal stromal tumor of the pancreas: case report with documentation of KIT gene mutation. (patologie.cz)
  • Daum O, Zalud R, Grossmann P, Mukensnabl P, Michal M. A case of imatinib-naive ileal fibrous stromal tumor with unusual morphology and double PDGFRA mutation. (patologie.cz)
  • Există mai mult de de tipuri de virusuri papiloma umane dintre care peste 30 au fost descrise ca infectând zona genitală Centers for Disease Control and Prevention, papiloma en ano. (adventube.ro)
  • The E6 protein of HPV-6 and HPV-11 binds p53 tumor suppressor protein less efficiently than that of HPV-16 and HPV-18 but, theoretically, could lead to accelerated degradation of the p53 protein. (medscape.com)
  • In the subcutaneous adipose tissue, near the lesion, there were several hyperdense strands [Figure 1c and d arrowhead], which were not infiltrative aspects of the tumor, but rather vascular structures. (units.it)
  • 2] If the tumor causes deep bone invasion, amputation might be warranted. (units.it)
  • Challenges in Diagnosing Biliary Stricture Diagnosis and staging of biliary tumors is difficult despite advances in imaging modalities. (medscape.com)
  • Braga JC, Nadal SR, Stiepcich M, Framil VM, Muller H. Buschke -Loewenstein tumor: identification of HPV type 6 and 11. (medscape.com)
  • These conditions are characterized by the appearance of papulo-tumor-like growths on the skin and mucous membranes. (trustedtablets.online)
  • [ 1 ] Even when the tumor is large, when it has been present for many years, and when it penetrates the bone, distant metastases are rare. (medscape.com)
  • Primary rectal adenocarcinoma has been reported to mimic giant condyloma of Buschke and Löwenstein (GCBL). (medscape.com)
  • Wiedemann A, Diekmann WP, Holtmann G, Kracht H. Report of a case with giant condyloma (Buschke-Lowenstein tumor) localized in the bladder. (medscape.com)
  • Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions. (medscape.com)
  • Perianal giant condyloma acuminatum (Buschke-Löwenstein tumor). (medscape.com)
  • Long CA, Lewis JM, Orucevic A. Primary rectal adenocarcinoma presenting as a giant perianal mass mimicking giant condyloma of Buschke-Lowenstein. (medscape.com)
  • Giant Condyloma of Buschke-Lowenstein: An Atypical Case - Medscape - Jan 05, 2012. (medscape.com)
  • Buschke-Lowenstein tumor or giant condyloma acuminatum is a rare cutaneous condition. (cancerworld.info)
  • The signs and symptoms of Buschke-Lowenstein tumor or giant condyloma acuminatum involve the development of a cauliflower-shaped mass around the region of the external genitals and abscess or fistula around the growing mass. (cancerworld.info)
  • Buschke-Lowenstein tumor or Giant condyloma acuminatum is a rare variety of venereal warts characterized by a locally invasive and large-sized tumor. (cancerworld.info)
  • The treatment of choice for Buschke-Lowenstein or the giant condyloma acuminatum includes a wide surgical excision to eradicate the tumor and surrounding tissue around the affected body region. (cancerworld.info)
  • 1. Giant condyloma acuminatum (Buschke-Lowenstein tumor): Combined treatment with surgery and chemotherapy. (nih.gov)
  • 3. Perianal giant condyloma acuminatum of Buschke-Loewenstein: a carcinoma-like condyloma or a condyloma-like carcinoma? (nih.gov)
  • 8. [Squamous cell carcinoma arising in a giant condyloma acuminatum - Buschke-Löwenstein tumour]. (nih.gov)
  • 13. Squamous Cell Carcinoma Arising from Perianal Buschke-Lowenstein Tumor (Giant Condyloma Acuminatum): Comprehensive Literature Review. (nih.gov)
  • 14. Giant condyloma acuminata of Buschke-Lowenstein: successful treatment mainly by an innovative surgical method. (nih.gov)
  • 18. Giant condyloma acuminatum - Buschke-Lowenstein disease - a literature review. (nih.gov)
  • Giant condyloma acuminatum (also known as a Buschke-Löwenstein tumor) is a rare cutaneous condition characterized by an aggressive, wart-like growth that is a verrucous carcinoma. (wikipedia.org)
  • Safi F, Bekdache O, Al-Salam S, Alashari M, Mazen T. Giant condyloma acuminatum of Buschke-Lowenstein tumour: disease development between 2000 and 2010. (wikipedia.org)
  • Frega A et al (2002) Giant condyloma acuminatum or buschke-Lowenstein tumor: review of the literature and report of three cases treated by CO 2 laser surgery. (springer.com)
  • A rare giant condyloma acuminatum, associated with HPV types 6 and 11, may cause a low-grade invasive squamous cell carcinoma, known as the Buschke- Lowenstein tumor. (iacdworld.org)
  • Buschke-Lowenstein tumor (giant condyloma) is a fungating, locally invasive, low-grade cancer attributed to HPV. (medscape.com)
  • 6. Giant Perineal Condyloma Acuminatum (Buschke-Lowenstein Tumour): A Case Report. (nih.gov)
  • Giant anorectal condyloma acuminatum of Buschke-Löwenstein presents difficult management decisions. (wikipedia.org)
  • Buschke-Lowenstein tumors usually displace and destroy adjacent structures as a result of compression. (cancerworld.info)
  • Owing to their impressive growth patterns, Buschke-Löwenstein tumors displace and destroy adjacent structures from compression. (wikipedia.org)
  • Buschke-Lowenstein tumor successful treatment by surgical excision alone: a case report. (medscape.com)
  • The CT scan of two patients with anorectal giant condylomata revealed the invasive nature of the lesion and the extent of the tumor. (cancerworld.info)
  • Exophytic tumor of the anogenital region associated with HPV infections. (nih.gov)
  • Chemotherapy may also be used to remove this tumor depending upon the size and spread of this tumor. (cancerworld.info)
  • When squamous carcinoma is present in the genital region of the body, it is known as the Buschke-Lowenstein tumor. (cancerworld.info)
  • Although it is known about Bushcke-Lowenstein tumors that these are slow-growing, these pain-causing tumors can easily invade the surrounding tissues of the genital region and cause damage as a result. (cancerworld.info)
  • For example, bowenoid papulosis , seborrheic keratoses, and Buschke-Lowenstein tumors -previously parts of the differential diagnosis of genital warts-all have been linked to HPV infections. (medscape.com)
  • It depends on the size of the Buschke-Lowenstein tumor, long-term outcome for patients, and response to treatment. (cancerworld.info)
  • A few factors that need consideration while opting for the treatment for Buschke-Lowenstein tumors. (cancerworld.info)
  • 12. Successful combined treatment of Buschke-Lowenstein tumor in anal canal with electroresection, photodynamic therapy and topical 5% imiquimod. (nih.gov)
  • In general, masses of Buschke-Lowenstein tumors are benign but there is a high potential for its transformation into a malignant form from a benign one in the long term, as does the rare risk for metastasis. (cancerworld.info)
  • Subsequently, the term "neoformans" was included to indicate "cancer or tumor-causing" in light of an association between the isolation of the organism and cancers. (medlink.com)
  • HPV proteins may also cause proteolytic degradation of the tumor suppressor gene p53. (medscape.com)
  • 20. Buschke-Löwenstein tumor in a human immunodeficiency virus-positive patient: a case report and short literature review. (nih.gov)
  • Auger and internal conversion (IC) electron emitters appropriately targeted to the DNA of tumors cells may, therefore, represent a new radiotherapeutic approach. (bvsalud.org)
  • However, not all the affected individuals with the human papillomavirus will develop a Buschke-Lowenstein tumor. (cancerworld.info)
  • The radiological findings enable the specialists in diagnosing the presence of this tumor in the human body. (cancerworld.info)
  • 17. Rapidly Invasive Buschke-Löwenstein Tumor Associated With Human Papillomavirus Types 6 and 52. (nih.gov)
  • However, these tumors usually do not spread to other parts of the body. (cancerworld.info)
  • Some other factors responsible for the Buschke-Lowenstein tumor may include alcoholism, diabetes, and a weak immune system. (cancerworld.info)
  • Crespo R, Puig F, Lanzon A, Borell A. Buschke-Lowenstein tumor and pregnancy: a case report. (medscape.com)
  • Buschke-Löwenstein tumor in childhood: a case report. (medscape.com)