The sudden sensation of being cold. It may be accompanied by SHIVERING.
An absence of warmth or heat or a temperature notably below an accustomed norm.
Botanically, a type of single-seeded fruit in which the pericarp enclosing the seed is a hard woody shell. In common usage the term is used loosely for any hard, oil-rich kernel. Of those commonly eaten, only hazel, filbert, and chestnut are strictly nuts. Walnuts, pecans, almonds, and coconuts are really drupes. Brazil nuts, pistachios, macadamias, and cashews are really seeds with a hard shell derived from the testa rather than the pericarp.
A climate characterized by COLD TEMPERATURE for a majority of the time during the year.
An abnormal elevation of body temperature, usually as a result of a pathologic process.
A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)
A species of migratory Old World locusts, in the family ACRIDIDAE, that are important pests in Africa and Asia.
Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals.
Woody, usually tall, perennial higher plants (Angiosperms, Gymnosperms, and some Pterophyta) having usually a main stem and numerous branches.
Adaptation to a new environment or to a change in the old.
I'm sorry for any confusion, but "Utah" is a proper noun and refers to a state in the United States, it does not have a medical definition. If you have any medical questions or need information on specific medical conditions or terms, I would be happy to help!
Single or multiple areas of PUS due to bacterial infection within the hepatic parenchyma. It can be caused by a variety of BACTERIA, local or disseminated from infections elsewhere such as in APPENDICITIS; CHOLECYSTITIS; PERITONITIS; and after LIVER TRANSPLANTATION.
Any aspect of the operations in the preparation, processing, transport, storage, packaging, wrapping, exposure for sale, service, or delivery of food.
The longterm manifestations of WEATHER. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.
Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.
Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.
The edible portions of any animal used for food including domestic mammals (the major ones being cattle, swine, and sheep) along with poultry, fish, shellfish, and game.

A randomized, double-blind comparative trial evaluating the safety of liposomal amphotericin B versus amphotericin B lipid complex in the empirical treatment of febrile neutropenia. L Amph/ABLC Collaborative Study Group. (1/19)

In this double-blind study to compare safety of 2 lipid formulations of amphotericin B, neutropenic patients with unresolved fever after 3 days of antibacterial therapy were randomized (1:1:1) to receive amphotericin B lipid complex (ABLC) at a dose of 5 mg/kg/d (n=78), liposomal amphotericin B (L Amph) at a dose of 3 mg/kg/d (n=85), or L Amph at a dose of 5 mg/kg/d (n=81). L Amph (3 mg/kg/d and 5 mg/kg/d) had lower rates of fever (23.5% and 19.8% vs. 57.7% on day 1; P<.001), chills/rigors (18.8% and 23.5% vs. 79.5% on day 1; P<.001), nephrotoxicity (14.1% and 14.8% vs. 42.3%; P<.01), and toxicity-related discontinuations of therapy (12.9% and 12.3% vs. 32.1%; P=.004). After day 1, infusional reactions were less frequent with ABLC, but chills/rigors were still higher (21.0% and 24.3% vs. 50.7%; P<.001). Therapeutic success was similar in all 3 groups.  (+info)

Rituximab dose-escalation trial in chronic lymphocytic leukemia. (2/19)

PURPOSE: To conduct a dose-escalation trial of rituximab in patients with chronic lymphocytic leukemia (CLL) to define the maximum-tolerated dose (MTD), to evaluate first-dose reactions in patients with high circulating lymphocyte counts, and to assess the efficacy at higher versus lower doses. PATIENTS AND METHODS: Fifty patients with CLL (n = 40) or other mature B-cell lymphoid leukemias (n = 10) were treated with four weekly infusions of rituximab. The first dose was 375 mg/m(2) for all patients; dose- escalation began with dose 2 but was held constant for each patient. Escalated doses were from 500 to 2,250 mg/m(2). RESULTS: Toxicity with the first dose (375 mg/m(2)) was noted in 94% of patients but was grade 1 or 2 in most, predominantly fever and chills. Six patients (12%) experienced severe toxicity with the first dose, including fever, chills, dyspnea, and hypoxia in all six patients, hypotension in five, and hypertension in one. Toxicity on subsequent doses was minimal until a dose of 2,250 mg/m(2) was achieved. Eight (67%) of 12 patients had grade 2 toxicity, including fever, chills, nausea, and malaise, although no patient had grade 3 or 4 toxicity. Severe toxicity with the first dose was significantly more common in patients with other B-cell leukemias, occurring in five (50%) of 10 patients versus one (2%) of 40 patients with CLL (P <.001). The overall response rate was 40%; all responses in patients with CLL were partial remissions. Response rates were 36% in CLL and 60% in other B-cell lymphoid leukemias. Response was correlated with dose: 22% for patients treated at 500 to 825 mg/m(2), 43% for those treated at 1,000 to 1,500 mg/m(2), and 75% for those treated at the highest dose of 2,250 mg/m(2) (P =.007). The median time to disease progression was 8 months. Myelosuppression and infections were uncommon. CONCLUSION: Rituximab has significant activity in patients with CLL at the higher dose levels. Severe first-dose reactions were uncommon in patients with CLL, even with high circulating lymphocyte counts, but were frequent in patients with other mature B-cell leukemias in which CD20 surface expression is increased. Efficacy of rituximab was also significant in this group of patients.  (+info)

Dacarbazine and interferon alpha with or without interleukin 2 in metastatic melanoma: a randomized phase III multicentre trial of the Dermatologic Cooperative Oncology Group (DeCOG). (3/19)

In several phase II-trials encouraging tumour responses rates in advanced metastatic melanoma (stage IV; AJCC-classification) have been reported for the application of biochemotherapy containing interleukin 2. This study was designed to compare the efficacy of therapy with dacarbazine (DTIC) and interferon alpha (IFN-alpha) only to that of therapy with DTIC and IFN-alpha with the addition of interleukin 2 (IL-2) in terms of the overall survival time and rate of objective remissions and to provide an elaborated toxicity profile for both types of therapy. 290 patients were randomized to receive either DTIC (850 mg/m(2)every 28 days) plus IFN-alpha2a/b (3 MIU/m(2), twice on day 1, once daily from days 2 to 5; 5 MIU/m(2)3 times a week from week 2 to 4) with or without IL-2 (4.5 MIU/m(2)for 3 hours i.v. on day 3; 9.0 MIU/m(2) i.v. day 3/4; 4.5 MIU/m(2) s.c. days 4 to 7). The treatment plan required at least 2 treatment cycles (8 weeks of therapy) for every patient. Of 290 randomized patients 281 were eligible for an intention-to-treat analysis. There was no difference in terms of survival time from treatment onset between the two arms (median 11.0 months each). In 273 patients treated according to protocol tumour response was assessable. The response rates did not differ between both arms (P = 0.87) with 18.0% objective responses (9.7% PR; 8.3% CR) for DTIC plus IFN-alpha as compared to 16.1% (8.8% PR; 7.3% CR) for DTIC, IFN-alpha and IL-2. Treatment cessation due to adverse reactions was significantly more common in patients receiving IL-2 (13.9%) than in patients receiving DTIC/IFN-alpha only (5.6%). In conclusion, there was neither a difference in survival time nor in tumour response rates when IL-2, applied according to the combined intravenous and subcutaneous schedule used for this study, was added to DTIC and IFN-alpha. However, toxicity was increased in melanoma patients treated with IL-2. Further phase III trials with continuous infusion and higher dosages must be performed before any final conclusions can be drawn on the potential usefulness of IL-2 in biochemotherapy of advanced melanoma.  (+info)

Therapeutic use of cytokines to modulate phagocyte function for the treatment of infectious diseases: current status of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and interferon-gamma. (4/19)

The innate immune system represents the initial arm of host defense against pathogenic bacteria, fungi, and parasites. Neutrophils, monocytes, and tissue-based macrophages are major cellular components of this system. The potential ability to augment activity of the innate immune system has increased dramatically during the past 2 decades, with the discovery and development of cytokines. Four cytokines, namely granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF), and interferon (IFN)-gamma, have received increasing attention as potential adjunctive agents for the treatment of infectious diseases. In various animal models of infection, therapeutic administration of each of the 4 cytokines has been shown to enhance pathogen eradication and to decrease morbidity and/or mortality. However, variable therapeutic efficacy has been reported in clinical trials conducted to date. This review summarizes the current status of the use of G-CSF, GM-CSF, M-CSF, and IFN-gamma in the treatment of infectious diseases.  (+info)

Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia. (5/19)

This multicenter phase 2 trial investigated safety and efficacy of a new immunochemotherapeutic regimen combining rituximab (R) and fludarabine (F) in patients with fludarabine- and anthracycline-naive chronic lymphocytic leukemia (CLL). The rationale for using R + F includes single-agent efficacy of both drugs, in vitro synergism of R and F, and no apparent overlapping toxicity. Of 31 eligible patients with B-CLL enrolled, 20 were previously untreated and 11 relapsed. Treatment consisted of fludarabine administered at standard doses (25 mg/m(2)/d; days 1-5, 29-33, 57-61, and 85-89) and rituximab (375 mg/m(2)/d) given on days 57, 85, 113, and 151. Side effects such as fever, chills, and exanthema were generally mild (National Cancer Institute Common Toxicity Criteria [NCI-CTC] grade 1/2 in 48% and grade 3 and/or 4 in 3% of patients). Fever and chills were mainly associated with the first rituximab infusion. Hematologic toxicity included neutropenia (grade 1 and/or 2 in 26%, grade 3 and/or 4 in 42%) and thrombocytopenia (grade 1 and/or 2 in 19%, grade 3 and/or 4 in 9%). One patient died of cerebral bleeding during prolonged thrombocytopenia after the second cycle of fludarabine. There were a total of 32 infections in 16 patients, none of which was fatal. The overall response rate (complete remission [CR] and partial remission [PR]) was 87% (27 of 31 evaluable patients). In 20 previously untreated patients, 17 (85%) responded. Ten of 31 patients achieved CR (5 of 20 untreated; 5 of 11 pretreated; 9 of 21 Binet stage B, 1 of 10 Binet stage C). The median duration of response was 75 weeks. We conclude that the combination of rituximab and fludarabine is feasible and effective in patients with B-CLL.  (+info)

An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab. (6/19)

The chimeric anti-CD20 monoclonal antibody rituximab has become part of the standard therapy for patients with non-Hodgkin's lymphoma (NHL). To date, more than 300 000 patients have been treated with rituximab worldwide, including patients with indolent and aggressive NHL, Hodgkin's disease and other B-cell malignancies. Combination of rituximab with cytotoxic agents or cytokines has been explored in a number of different studies. Rituximab is now also approved for patients with diffuse large B-cell lymphoma when combined with standard CHOP chemotherapy (cyclophosphamide, doxorubicin, vincristine and prednisone). The monoclonal antibody is generally well tolerated. Most adverse events are infusion-associated, including chills, fever and rigor related to the release of cytokines.  (+info)

A major outbreak of severe acute respiratory syndrome in Hong Kong. (7/19)

BACKGROUND: There has been an outbreak of the severe acute respiratory syndrome (SARS) worldwide. We report the clinical, laboratory, and radiologic features of 138 cases of suspected SARS during a hospital outbreak in Hong Kong. METHODS: From March 11 to 25, 2003, all patients with suspected SARS after exposure to an index patient or ward were admitted to the isolation wards of the Prince of Wales Hospital. Their demographic, clinical, laboratory, and radiologic characteristics were analyzed. Clinical end points included the need for intensive care and death. Univariate and multivariate analyses were performed. RESULTS: There were 66 male patients and 72 female patients in this cohort, 69 of whom were health care workers. The most common symptoms included fever (in 100 percent of the patients); chills, rigors, or both (73.2 percent); and myalgia (60.9 percent). Cough and headache were also reported in more than 50 percent of the patients. Other common findings were lymphopenia (in 69.6 percent), thrombocytopenia (44.8 percent), and elevated lactate dehydrogenase and creatine kinase levels (71.0 percent and 32.1 percent, respectively). Peripheral air-space consolidation was commonly observed on thoracic computed tomographic scanning. A total of 32 patients (23.2 percent) were admitted to the intensive care unit; 5 patients died, all of whom had coexisting conditions. In a multivariate analysis, the independent predictors of an adverse outcome were advanced age (odds ratio per decade of life, 1.80; 95 percent confidence interval, 1.16 to 2.81; P=0.009), a high peak lactate dehydrogenase level (odds ratio per 100 U per liter, 2.09; 95 percent confidence interval, 1.28 to 3.42; P=0.003), and an absolute neutrophil count that exceeded the upper limit of the normal range on presentation (odds ratio, 1.60; 95 percent confidence interval, 1.03 to 2.50; P=0.04). CONCLUSIONS: SARS is a serious respiratory illness that led to significant morbidity and mortality in our cohort.  (+info)

Risk of transmission of leptospirosis from infected cattle to dairy workers in southern Israel. (8/19)

BACKGROUND: Leptospirosis is a zoonotic disease that occurs worldwide, found predominantly in agricultural workers, port workers and dairy workers. OBJECTIVE: To investigate the risk of disease transmission to dairy workers following an outbreak in 1999 of Leptospirosis hardjo in the dairy herds of two kibbutzim in southern Israel. METHODS: A seroepidemiologic survey of all the dairy workers from these two kibbutzim was conducted, including individual interview and examination. Data were collected on the presence of clinical symptoms of leptospirosis during the previous month. One month later the medical personnel on the two kibbutzim were contacted in order to determine if any worker had subsequently developed clinical signs or symptoms of leptospirosis. All dairy workers had blood drawn for serology. Those workers whose initial serology had been borderline for leptospirosis had a repeated serology test between 2 and 4 weeks later. Doxycycline was given prophylactically to all dairy workers on one kibbutz only. RESULTS: Either with or without chemoprophylaxis, no dairy workers exposed to herds infected with Leptospira hardjo showed evidence of seroconversion or disease. This indicated a low risk of transmission of this serovar from cows to dairy workers. CONCLUSION: Since human illness with leptospirae can cause illness associated with significant morbidity, we recommend that physicians make an informed decision regarding doxycycline prophylaxsis for dairy workers exposed to cattle herds infected with Leptospira hardjo.  (+info)

"Chills" is a medical term that refers to the sensation of shivering or feeling cold despite being in a warm environment. It is often accompanied by goosebumps on the skin and can be a symptom of various medical conditions, such as infections, hypothermia, or certain medications. During chills, the muscles involuntarily contract and relax rapidly to produce heat, causing the body temperature to rise in an attempt to fight off infection or illness. It is important to seek medical attention if experiencing persistent or severe chills, especially when accompanied by other symptoms such as fever, cough, or chest pain.

"Cold temperature" is a relative term and its definition can vary depending on the context. In general, it refers to temperatures that are lower than those normally experienced or preferred by humans and other warm-blooded animals. In a medical context, cold temperature is often defined as an environmental temperature that is below 16°C (60.8°F).

Exposure to cold temperatures can have various physiological effects on the human body, such as vasoconstriction of blood vessels near the skin surface, increased heart rate and metabolic rate, and shivering, which helps to generate heat and maintain body temperature. Prolonged exposure to extreme cold temperatures can lead to hypothermia, a potentially life-threatening condition characterized by a drop in core body temperature below 35°C (95°F).

It's worth noting that some people may have different sensitivities to cold temperatures due to factors such as age, health status, and certain medical conditions. For example, older adults, young children, and individuals with circulatory or neurological disorders may be more susceptible to the effects of cold temperatures.

In a medical context, "nuts" are typically referred to as a type of food that comes from dry fruits with one seed in them. They are often high in healthy fats, fiber, protein, and various essential nutrients. Examples include almonds, walnuts, hazelnuts, cashews, pistachios, and pecans. However, it's important to note that some people may have allergies to certain types of nuts, which can cause serious health problems.

A "cold climate" is not a medical term, but rather a geographical and environmental term. However, it is often used in the context of discussing health and medical issues, as cold climates can have various effects on human health.

In general, a cold climate is defined as a region where the average temperature remains below 15°C (59°F) throughout the year or where winter temperatures are consistently below freezing. These climates can be found in high latitudes, such as in the Arctic and Antarctic regions, as well as in mountainous areas at higher altitudes.

Exposure to cold temperatures can have both positive and negative effects on human health. On the one hand, cold weather can help to reduce inflammation and may have some benefits for people with certain medical conditions, such as multiple sclerosis. However, exposure to extreme cold can also increase the risk of hypothermia, frostbite, and other cold-related injuries.

Additionally, cold climates can exacerbate respiratory problems, such as asthma and bronchitis, and may increase the risk of developing respiratory infections like the common cold or flu. People with heart conditions may also be at greater risk in cold weather, as their blood vessels constrict to conserve heat, which can increase blood pressure and put additional strain on the heart.

Overall, while cold climates are not inherently "medical" in nature, they can have significant impacts on human health and well-being, particularly for vulnerable populations such as the elderly, young children, and people with chronic medical conditions.

Fever, also known as pyrexia or febrile response, is a common medical sign characterized by an elevation in core body temperature above the normal range of 36.5-37.5°C (97.7-99.5°F) due to a dysregulation of the body's thermoregulatory system. It is often a response to an infection, inflammation, or other underlying medical conditions, and it serves as a part of the immune system's effort to combat the invading pathogens or to repair damaged tissues.

Fevers can be classified based on their magnitude:

* Low-grade fever: 37.5-38°C (99.5-100.4°F)
* Moderate fever: 38-39°C (100.4-102.2°F)
* High-grade or severe fever: above 39°C (102.2°F)

It is important to note that a single elevated temperature reading does not necessarily indicate the presence of a fever, as body temperature can fluctuate throughout the day and can be influenced by various factors such as physical activity, environmental conditions, and the menstrual cycle in females. The diagnosis of fever typically requires the confirmation of an elevated core body temperature on at least two occasions or a consistently high temperature over a period of time.

While fevers are generally considered beneficial in fighting off infections and promoting recovery, extremely high temperatures or prolonged febrile states may necessitate medical intervention to prevent potential complications such as dehydration, seizures, or damage to vital organs.

Betaine, also known as trimethylglycine, is a naturally occurring compound that can be found in various foods such as beets, spinach, and whole grains. In the body, betaine functions as an osmolyte, helping to regulate water balance in cells, and as a methyl donor, contributing to various metabolic processes including the conversion of homocysteine to methionine.

In medical terms, betaine is also used as a dietary supplement and medication. Betaine hydrochloride is a form of betaine that is sometimes used as a supplement to help with digestion by providing additional stomach acid. Betaine anhydrous, on the other hand, is often used as a supplement for improving athletic performance and promoting liver health.

Betaine has also been studied for its potential role in protecting against various diseases, including cardiovascular disease, diabetes, and neurological disorders. However, more research is needed to fully understand its mechanisms of action and therapeutic potential.

"Locusta migratoria" is the scientific name for the migratory locust, which is a species of short-horned grasshopper. While it is not a medical term, I can provide some general information about this insect.

Migratory locusts are known for their ability to form large swarms that can travel long distances, consuming vast amounts of vegetation and causing significant damage to crops and pastures. They are native to Africa, Asia, and Europe but have been introduced to other parts of the world as well. The migratory locust is a agricultural pest and can pose a serious threat to food security in areas where they occur in large numbers.

From a medical perspective, some species of grasshoppers, including the migratory locust, can carry various pathogens that may affect humans and animals if ingested or come into contact with mucous membranes. However, there are no specific medical concerns associated with "Locusta migratoria" itself.

"Drug evaluation" is a medical term that refers to the systematic process of assessing the pharmacological, therapeutic, and safety profile of a drug or medication. This process typically involves several stages, including preclinical testing in the laboratory, clinical trials in human subjects, and post-marketing surveillance.

The goal of drug evaluation is to determine the efficacy, safety, and optimal dosage range of a drug, as well as any potential interactions with other medications or medical conditions. The evaluation process also includes an assessment of the drug's pharmacokinetics, or how it is absorbed, distributed, metabolized, and eliminated by the body.

The findings from drug evaluations are used to inform regulatory decisions about whether a drug should be approved for use in clinical practice, as well as to provide guidance to healthcare providers about how to use the drug safely and effectively.

I'm sorry for any confusion, but "trees" is not a medical term. It is a common term used in various fields, including biology, ecology, and dendrology, to refer to a woody perennial plant with a single stem or trunk that supports branches and leaves in most species.

If you have any questions related to medical terminology or health-related topics, please provide more context so I can offer an accurate and helpful response.

Acclimatization is the process by which an individual organism adjusts to a change in its environment, enabling it to maintain its normal physiological functions and thus survive and reproduce. In the context of medicine, acclimatization often refers to the body's adaptation to changes in temperature, altitude, or other environmental factors that can affect health.

For example, when a person moves from a low-altitude area to a high-altitude area, their body may undergo several physiological changes to adapt to the reduced availability of oxygen at higher altitudes. These changes may include increased breathing rate and depth, increased heart rate, and altered blood chemistry, among others. This process of acclimatization can take several days or even weeks, depending on the individual and the degree of environmental change.

Similarly, when a person moves from a cold climate to a hot climate, their body may adjust by increasing its sweat production and reducing its heat production, in order to maintain a stable body temperature. This process of acclimatization can help prevent heat-related illnesses such as heat exhaustion and heat stroke.

Overall, acclimatization is an important physiological process that allows organisms to adapt to changing environments and maintain their health and well-being.

I'm sorry for any confusion, but "Utah" is not a medical term or concept. It is a geographical location, being the 45th state admitted to the United States of America. If you have any questions related to medical topics, I would be happy to try and help answer those for you!

A pyogenic liver abscess is a localized collection of pus within the liver parenchyma caused by an infectious process. It's typically characterized by the presence of a purulent material, which can be composed of white blood cells (neutrophils), necrotic debris, and microorganisms. The infection usually spreads to the liver through the hepatic blood vessels from a primary focus of infection elsewhere in the body, such as the gastrointestinal tract, lungs, or dental sources.

The most common causative organisms are Escherichia coli, Klebsiella pneumoniae, and Streptococcus species; however, anaerobes and fungi can also be responsible in certain populations. The clinical presentation of pyogenic liver abscess may include fever, chills, right upper quadrant abdominal pain, nausea, vomiting, and signs of systemic infection. Diagnosis is usually confirmed with imaging techniques such as ultrasound or CT scan, followed by aspiration and culture of the pus for identification of the causative organism(s) and antibiogram-guided antimicrobial therapy. Drainage of the abscess, either percutaneously or surgically, might be required in specific cases to ensure resolution and prevent recurrence.

"Food handling" is not a term that has a specific medical definition. However, in the context of public health and food safety, it generally refers to the activities involved in the storage, preparation, and serving of food in a way that minimizes the risk of contamination and foodborne illnesses. This includes proper hygiene practices, such as handwashing and wearing gloves, separating raw and cooked foods, cooking food to the correct temperature, and refrigerating or freezing food promptly. Proper food handling is essential for ensuring the safety and quality of food in various settings, including restaurants, hospitals, schools, and homes.

Climate, in the context of environmental science and medicine, refers to the long-term average of weather conditions (such as temperature, humidity, atmospheric pressure, wind, rainfall, and other meteorological elements) in a given region over a period of years to decades. It is the statistical description of the weather patterns that occur in a particular location over long periods of time.

In medical terms, climate can have significant impacts on human health, both physical and mental. For example, extreme temperatures, air pollution, and ultraviolet radiation levels associated with certain climates can increase the risk of respiratory and cardiovascular diseases, heat-related illnesses, and skin cancer. Similarly, changes in climate patterns can affect the distribution and prevalence of infectious diseases, such as malaria and Lyme disease.

Climate change, which refers to significant long-term changes in the statistical distribution of weather patterns over periods ranging from decades to millions of years, can have even more profound impacts on human health, including increased rates of heat-related illnesses and deaths, worsening air quality, and altered transmission patterns of infectious diseases.

Climate change, as defined medically, refers to the long-term alterations in the statistical distribution of weather patterns caused by changes in the Earth's climate system. These changes can have significant impacts on human health and wellbeing.

Medical professionals are increasingly recognizing the importance of addressing climate change as a public health issue. The World Health Organization (WHO) has identified climate change as one of the greatest threats to global health in the 21st century, with potential impacts including increased heat-related mortality, more frequent and severe natural disasters, changes in the distribution of infectious diseases, and decreased food security.

Climate change can also exacerbate existing health disparities, as vulnerable populations such as children, the elderly, low-income communities, and those with chronic medical conditions are often disproportionately affected by its impacts. As a result, addressing climate change is an important public health priority, and medical professionals have a critical role to play in advocating for policies and practices that reduce greenhouse gas emissions and promote adaptation to the changing climate.

I'm sorry for any confusion, but "seasons" is not a term that has a medical definition. Seasons refer to the four divisions of the year (spring, summer, autumn or fall, and winter) based on the position of the earth in its orbit around the sun. If you have any questions related to health or medicine, I'd be happy to try to help answer those!

Intravenous (IV) infusion is a medical procedure in which liquids, such as medications, nutrients, or fluids, are delivered directly into a patient's vein through a needle or a catheter. This route of administration allows for rapid absorption and distribution of the infused substance throughout the body. IV infusions can be used for various purposes, including resuscitation, hydration, nutrition support, medication delivery, and blood product transfusion. The rate and volume of the infusion are carefully controlled to ensure patient safety and efficacy of treatment.

Amphotericin B is an antifungal medication used to treat serious and often life-threatening fungal infections. It works by binding to the ergosterol in the fungal cell membrane, creating pores that lead to the loss of essential cell components and ultimately cell death.

The medical definition of Amphotericin B is:

A polyene antifungal agent derived from Streptomyces nodosus, with a broad spectrum of activity against various fungi, including Candida, Aspergillus, Cryptococcus, and Histoplasma capsulatum. Amphotericin B is used to treat systemic fungal infections, such as histoplasmosis, cryptococcosis, candidiasis, and aspergillosis, among others. It may be administered intravenously or topically, depending on the formulation and the site of infection.

Adverse effects associated with Amphotericin B include infusion-related reactions (such as fever, chills, and hypotension), nephrotoxicity, electrolyte imbalances, and anemia. These side effects are often dose-dependent and may be managed through careful monitoring and adjustment of the dosing regimen.

In a medical context, "meat" generally refers to the flesh of animals that is consumed as food. This includes muscle tissue, as well as fat and other tissues that are often found in meat products. However, it's worth noting that some people may have dietary restrictions or medical conditions that prevent them from consuming meat, so it's always important to consider individual preferences and needs when discussing food options.

It's also worth noting that the consumption of meat can have both positive and negative health effects. On the one hand, meat is a good source of protein, iron, vitamin B12, and other essential nutrients. On the other hand, consuming large amounts of red and processed meats has been linked to an increased risk of heart disease, stroke, and certain types of cancer. Therefore, it's generally recommended to consume meat in moderation as part of a balanced diet.

When it does not accompany a high fever, it is normally a light chill. Sometimes a chill of medium power and short duration may ... Severe chills with violent shivering are called rigors. Chills are commonly caused by inflammatory diseases, such as influenza ... Chills is a feeling of coldness occurring during a high fever, but sometimes is also a common symptom which occurs alone in ... Cold chill Goose bumps Night sweats Huether, Sue E. (2014). Pathophysiology: The Biologic Basis for Disease in Adults and ...
... resource reduction competition and its Chill Out video competition. ... Chill Out 2011 Past Sponsors and Partners The National Wildlife Federations Campus Ecology team would like to thank the ... Chill Out: Campus Solutions to Global Warming seeks to advance and celebrate the innovators of global warming solutions on ... Playing in Traffic is a proud music partner of Chill Out. Partners: Americas Greenest Campus is the largest nationwide contest ...
Black Knight, Inc. Out of focus since 1908.. That night, Jack is down in the basement when he finds a dungeon map laid out on the table that resembles the floor plan of his house, and a black knight figure stands on the board. As Jack makes a mad dash to Jacksons room, incredibly tense music begins to play in order to distract the audience from the fact that Jack is running around like an idiot for basically no reason. Its amazing. With that music going, it almost feels like Jack isnt massively overreacting! Jackson is unfortunately fine. Laura steps outside and finds a red rose on the doorstep. Meanwhile, Hanee and his father argue about the ins and outs of selling Christmas trees. As you can imagine, its absolutely titillating. Hanee goes off into the woods to chop down a few more trees, only to find a red rose on the ground. Moment after he picks it up, a black knight on a horse rides up and stabs him to death. That ought to teach him to throw snowballs! We cut to Russell, who is working ...
Midway through the equally graphic "Dopeman," the fight broke out and a chill of tension swept the hall. Ice Cube, one of the ...
Chills™ collection is dedicated to pet supplies that help your pet get into the Halloween spirit. ... Thrills & Chills™ Halloween X-Large Plush Trick or Treat Bone Dog Toy - Squeaker. ... At PetSmart, our Thrills & Chills™ collection is dedicated to pet supplies that help your pet get into the Halloween spirit. ... From toys and treats to clothes and costumes, PetSmarts Thrills & Chills collection has something for every pet in your life. ...
... I never knew what the intense physical sensations certain songs gave me were until I heard ... so researchers thought at first that they got chills more often simply because they tended to listen to more chill-inducing ... But none of the non-musical ASMR trigger videos give me the chills. Yet I couldnt help but feel that some of the pushback ... If you build it, the chills will come.. That means musicians can make music that does this on purpose. And for real, man, they ...
On the fifth anniversary this month, CNN.com will be streaming footage all day of the networks televised coverage from Sept. 11th, 2001, enabling viewers to relive it as events unfolded. What do you think?
Turkey: Journalists Arrests Chills Free Speech. Some Had Done Critical Reporting About the Criminal Justice System ... will have a chilling effect on free speech, Human Rights Watch said. The nine were accused of links to the alleged "Ergenekon" ... which Human Rights Watch considers a form of harassment and which can have a chilling effect on the legitimate right to free ...
The A6 Avant wagon has been a staple of the Audi lineup for years, so its no surprise that an all-new model is on the way to compliment the recently debuted sedan.
Learn more about our range of Chilled Pancakes ... Get quality Chilled Pancakes at Tesco. Shop in store or online ...
chill out (third-person singular simple present chills out, present participle chilling out, simple past and past participle ... Since Im between projects, I think Ill just chill out.. I wish I could chill out about the neighbors barking dog, but it ... Synonyms: chill, hang out. Hey, we should chill out together this weekend. ... Ed: Chill out. Everyones all right. / Shaun: Stop telling me to chill out! ...
... David Cameron felt it necessary to don trousers when he stepped out for a jog in ...
This is the digital download of the first Sycamore Drive 7 record, Chills / Mortimers Melody. These songs were the first to ...
Hopefully, you will never have to face any of these terrifying war machines - but here are ten that give us chills. ... What makes Orlan give us chills is that its operators are using it to target civilians and civilian infrastructure. They are ...
Your choice of tea - freshly brewed and chilled - by the gallon: Sweetened Black, Unsweetened Black, Unsweetened Exotic ...
Listen to Chill here on TuneIn! Listen anytime, anywhere! ... Spurious his Chill Out Now podcast is full of tunes with ... Tune in to The Session for the best in electronica, acid jazz, chill, lounge and downtempo. Every weekday night we take you on ... Discover a world of great new indie-dance, deep house, and chill-out music by tuning into The Dream House - the official ... KU DE TA Radio is a sublime music experience, featuring chill out, down tempo, lounge through to stylish sunset house grooves. ...
The updated 2001 version of the wind chill formula. National Weather Service. Why should I care about wind chill?. Wind chill ... What is wind chill?. "Its how it feels when youre out in cold weather with wind blowing," says Bob Oravec, a lead forecaster ... Wind chill isnt what you think it is. The math may be unreliable, but the frostbite is real. ... Researchers at the NWS use a mathematical formula to calculate wind chill. In that formula, the wind speed in miles per hour (v ...
View Photos From Chill with Schill 2023. Activities. Check back for updates. All food, activities, and giveaways are free and ... Chill with Schill. Take a break with President Schill and Max. Tuesday, May 30, 2023. 11:30 a.m. to 2 p.m.. Norris University ... Chill with Schill Schedule. Activity. Time. Location. Activity Tables with Campus Resources: Northwestern Dietician, Health ...
Reason for the interruption: Install 30-inch in diameter automated valves in the Chilled Water Plant as part of the ongoing ... What does this affect: Cooling to buildings and equipment that uses chilled water for cooling. ...
pretty_chill_girl. New Scratcher Joined 2 years, 8 months ago United States ...
Sticky: Chiller/ac unit Started by Pimpsho, 11-20-2003 06:23 PM 29 Pages •. 1 2 3 4 5 ... 29 ... Sticky: Water_Chiller gallery Started by water_cooler 20, 03-04-2004 04:48 PM 11 Pages •. 1 2 3 4 5 ... 11 ... Massive Water Chiller Started by Stewie007, 04-12-2013 04:43 PM 10 Pages •. 1 2 3 4 5 ... 10 ... Water Chiller lost performance. Help getting it back to performing at top temps -21c Started by chispy, 12-06-2018 09:28 AM ...
The Chill Vibes Sunglasses are 92% cupronickel, 8% polycarbonate wire-frame sunglasses with 100% polycarbonate sunset lens. ...
If you put chilled meat right into the oven, your oven will have to raise its temperature by 90 degrees (40+90=130). If the ... Burning questions: Why not cook chilled chops?. By ERICA [email protected]. June 15, 2010. ...
Now that trailer seems to have made its way online for all to see, and it will give you chills. Check it out in the video below ... The whole thing gives you chills and is immaculately put together. The way the music crescendos with the images onscreen is ...
Discover whats missing in your discography and shop for Chill Tribe Records releases. ... Explore releases from the Chill Tribe Records label. ...
Read about Oceanic Softness from All Night Chill Makerss All Night Chill Waves and see the artwork, lyrics and similar artists ...
Once I finish chilling I refill the containers with the chiller water and put them in the garage to return to room temperature ... Chill 12 gallons of wort from boiling to 65F with as few gallons of water possible. Method Using a recirc through my IC and a ... Or you could chill your recirc water in the fridge first.. You also may need to think about the heat generated by your ... 1) Chill to 80F then transfer to the fermenter.. 2) Place fermenter in a tub of ice water and let sit (stir occasionally) until ...
Take a chill pill and relax as we are here to guide you along the steps t… Read More ...
Expect strong language and adult humour as we follow the lives of the Bad Boy Chiller Crew on and off stage. Turn on Parental ...
  • Chills is a feeling of coldness occurring during a high fever, but sometimes is also a common symptom which occurs alone in specific people. (wikipedia.org)
  • When it does not accompany a high fever, it is normally a light chill. (wikipedia.org)
  • Title : Malaria "chills and fever" Corporate Authors(s) : United States. (cdc.gov)
  • If you experience any of the following symptoms during or for 24 hours after your infusion, tell your doctor immediately: fever, chills, hives, difficulty breathing or swallowing, slowed breathing, fast heartbeat, tightening of the throat, or chest pain. (medlineplus.gov)
  • better source needed] Malaria is one of the common reasons for chills and rigors. (wikipedia.org)
  • In malaria, the parasites enter the liver, grow there and then attack the red blood cells which causes rupture of these cells and release of a toxic substance hemozoin which causes chills recurring every 3 to 4 days. (wikipedia.org)
  • At PetSmart, our Thrills & Chills™ collection is dedicated to pet supplies that help your pet get into the Halloween spirit. (petsmart.com)
  • From toys and treats to clothes and costumes, PetSmart's Thrills & Chills collection has something for every pet in your life. (petsmart.com)
  • What is wind chill temperature? (popsci.com)
  • Instead, they're using a somewhat mysterious calculation to determine what's known as wind chill. (popsci.com)
  • With some regions of the US experiencing the coldest air of the season right now, it's necessary to understand what wind chill is and why it's an important metric. (popsci.com)
  • What is wind chill? (popsci.com)
  • You're producing a wind chill for that hotter surface," Oravec says. (popsci.com)
  • Researchers at the NWS use a mathematical formula to calculate wind chill. (popsci.com)
  • In 1945, scientists Paul Siple and Charles Passel created the original wind chill index, aptly named the Siple and Passel Index, by experimenting in Antarctica with how long water took to freeze in different wind speeds, according to the NWS . (popsci.com)
  • It's important to note that wind chill has its limitations . (popsci.com)
  • However, Oravec says wind chill is useful as a quick gauge for how to bundle up. (popsci.com)
  • The updated 2001 version of the wind chill formula. (popsci.com)
  • Why should I care about wind chill? (popsci.com)
  • Wind chill doesn't just make it uncomfortable to be outdoors-it can also make it unsafe. (popsci.com)
  • The table above shows the wind chill at different temperatures and wind speeds, and also how long it would take for exposed skin to get frostbitten in different wind chill temperatures. (popsci.com)
  • But there are ways to protect yourself against wind chill and frostbite. (popsci.com)
  • The average temperature within the Arctic Circle in October is about -10 C, but last year runners attempting the same feat faced a blistering wind chill of -36C. (oxfordmail.co.uk)
  • Equinox Sounds has released Future Chill: MIDI , a collection that features the melodic content from their popular 'Future Chill' collection in MIDI format. (kvraudio.com)
  • Chilling injury index, weight loss , electrolyte leakage and malondialdehyde (MDA) content of control fruit increased during storage. (bvsalud.org)
  • Chilling injury improved phenylalanine ammonia-lyase (PAL), polyphenol oxidase (PPO), and peroxidase (POD) activities, which are correlated with the increase of total phenolic content and pulp browning of eggplant fruit . (bvsalud.org)
  • Try this Chilled Raspberry Cheesecake recipe, or contribute your own. (bigoven.com)
  • ASMR is different from frisson , the kind of chill most people get from music. (buzzfeed.com)
  • If you put chilled meat right into the oven, your oven will have to raise its temperature by 90 degrees (40+90=130). (newsday.com)
  • What does this affect: Cooling to buildings and equipment that uses chilled water for cooling. (k-state.edu)
  • Reason for the interruption: Install 30-inch in diameter automated valves in the Chilled Water Plant as part of the ongoing construction to upgrade the Manhattan campus' chilled water system. (k-state.edu)
  • Water Chiller lost performance. (xtremesystems.org)
  • Chilled Water Cooling Using Peltier/TEC Assembly Now 17 Months in Operation. (xtremesystems.org)
  • Chill 12 gallons of wort from boiling to 65F with as few gallons of water possible. (homebrewersassociation.org)
  • Once I finish chilling I refill the containers with the chiller water and put them in the garage to return to room temperature (or colder this time of year) before going back into the freeze for the next batch. (homebrewersassociation.org)
  • Please note that water can be used as coolant, but will result in reduced performance, and alcohol-based coolants cannot be used with this chiller. (thorlabs.com)
  • These allow chilled water packs to be cooled in the same refrigerators in which the vaccines are stored, this creates an entirely freeze-free cold chain solution from clinic to outreach. (who.int)
  • The approach is tested on a physics-based model of a water-cooled screw chiller. (lu.se)
  • Istanbul) - The arrest of nine journalists and writers on March 3, 2011, in the absence of clear reasonable cause, will have a chilling effect on free speech, Human Rights Watch said. (hrw.org)
  • We successfully captured 204 chills-eliciting videos of three categories: music, film, and speech. (mit.edu)
  • Beginning in 2006, we held the annual Chill Out competition to recognize the projects and people making a difference. (nwf.org)
  • The only way to get better is to surround yourself with chill people who are smarter than you, but listen to what you have to say. (lu.se)
  • This is why we need to surround ourselves with chill people who are smarter than you, but who listen to what you have to say - it's the only way to improve and it's what excites me most about working at Cubbit. (lu.se)
  • Chilling Time! (xtremesystems.org)
  • Does this participant have any allergies, dietary restrictions, current health concerns, and/or behavioral, mental, or psychological conditions that may impact their time at Chill? (tfaforms.com)
  • Hopefully, you will never have to face any of these terrifying war machines - but here are ten that give us chills. (slashgear.com)
  • Now that trailer seems to have made its way online for all to see, and it will give you chills. (cinemablend.com)
  • Playing in Traffic is a proud music partner of Chill Out. (nwf.org)
  • Petition · "Bring back the show zero chill! (change.org)
  • The image to the right shows the connectors with tubing attached to the coolant in and out ports on the back panel of the LK220 chiller. (thorlabs.com)
  • Researchers say this acts as a chilling effect, when users choose not to do something that is legally permitted for fear of getting into trouble. (sciencedaily.com)
  • Effect of 24-epibrassinolide treatment on the metabolism of eggplant fruits in relation to development of pulp browning under chilling stress. (bvsalud.org)
  • This study aims to investigate the effect of 24-epibrassinolide (EBR) on the metabolism in relation to development of chilling injury -induced pulp browning of eggplant fruit . (bvsalud.org)
  • These results suggest that EBR may inhibit chilling injury and pulp browning in eggplant fruit during cold storage. (bvsalud.org)
  • I hereby irrevocably release, consent and allow The Chill Foundation and its Sponsors to use my/my dependent's photographs/likeness/voice, as it pertains to participation with The Chill Foundation programs, in any manner for promotional efforts without expectation of any reimbursement in connection with its use. (tfaforms.com)
  • We still have to wait until October 3 for Gone Girl's theatrical release, but this chilling new trailer for the flick, based on the best-selling book of the same name, is helping to tide us over. (okmagazine.com)
  • Keep your beverages as cool as your adventures with our range of ChillBak™ Soft Coolers, made for the ultimate chill. (camelbak.com)
  • We then tested the top 50 videos in the database on 600+ participants and validated a gold standard of 10 stimuli with a. 9 probability of generating chills. (mit.edu)
  • The National Wildlife Federation's Campus Ecology team would like to thank the following who have been great partners and sponsors of Chill Out in the past. (nwf.org)
  • The increased set point causes the body temperature to rise (pyrexia), but also makes the patient feel cold or chills until the new set point is reached. (wikipedia.org)
  • Cold chill Goose bumps Night sweats Huether, Sue E. (2014). (wikipedia.org)
  • Centrifugal Chiller achieved high efficiency through Two-stage Compressor. (lg.com)
  • Based on thermoelectric cooler elements (TECs), this chiller can operate at low noise levels while also achieving high temperature accuracies of 0.01 °C. For more information about the cooling capacity and flow performance, please see the Graphs tab. (thorlabs.com)
  • In 2011 the National Wildlife Federation's Campus Ecology Program became a lead partner on the Campus Conservation Nationals (CCN) resource reduction competition and are keeping the Chill Out spirit alive by hosting a video component for the competition. (nwf.org)
  • Students are encouraged to plan events surrounding the Chill Out broadcast to engage even more students in climate action on campus. (nwf.org)
  • Kendeda Fund is a proud sponsor of National Wildlife Federation's Chill Out: Campus Solutions to Global Warming program. (nwf.org)
  • Burning questions: Why not cook chilled chops? (newsday.com)
  • The LK220 liquid chiller can be controlled locally through the front panel, where the knob is used to make setting adjustments. (thorlabs.com)
  • Shivering also occurs along with chills because the patient's body produces heat during muscle contraction in a physiological attempt to increase body temperature to the new set point. (wikipedia.org)
  • With optimized Two-stage compressing cycle, energy efficiency has been improved and operation costs has been reduced as opposed to the previous One-stage Centrifugal Chiller. (lg.com)
  • For easy tube connection, the LK220 chiller features two valved CPC ® thumb latch quick-disconnect to ferruleless compression fittings, which accept semi-rigid plastic tubing with a 0.17" (4.3 mm) inner diameter (ID) and a 1/4" (6.4 mm) outer diameter (OD). (thorlabs.com)
  • It is okay to put small portions of hot food in the refrigerator since they will chill faster. (cdc.gov)
  • Chill Out seeks to provide hope and solutions amidst the problems and consequences of global warming. (nwf.org)
  • Since I'm between projects, I think I'll just chill out . (wiktionary.org)
  • Inspired by Be More Chill, this snug, form-fitting beanie is perfect for fans of the musical. (etsy.com)
  • Newly reissued by Fire Records, these iconic early albums from The Chills catalogue have been remastered for a super sweet moment of ear candy, perfect for rediscovery. (firerecords.com)
  • The winter chill of Geneva is warmed in the last week of January every year by the meeting of the WHO Executive Board, which gathers to follow up on decisions of the World Health Assembly and provide guidance and direction to the WHO Secretariat. (who.int)

No images available that match "chills"