'Frozen foods' in a medical context typically refers to prepared or raw food items that have been rapidly cooled then stored at freezing temperatures, typically below -18 degrees Celsius, to minimize microbial growth and enzymatic reactions, thereby extending their shelf life.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).

Erdheim-Chester disease: pulmonary infiltration responding to cyclophosphamide and prednisolone. (1/34)

Erdheim-Chester disease is a rare multisystem histiocytic disorder in which death most commonly results from pulmonary or cardiac involvement. We report the case history of a 55 year old man with this condition with extensive and progressive pulmonary disease. He had no response to prednisolone alone, but treatment with prednisolone plus cyclophosphamide was associated with a rapid improvement in symptoms, lung function, and the chest radiographic appearance. He subsequently showed a symptomatic, functional, and radiological deterioration, followed by a marked slowing in the rate of decline. He currently remains stable 41 months after treatment was initiated. This is the first report of pulmonary Erdheim-Chester disease showing improvement in both lung function and symptoms with any form of treatment.  (+info)

Erdheim-chester disease mimicking multiple meningiomas syndrome. (2/34)

We describe a rare case of non-Langerhans histiocytosis, consistent with Erdheim-Chester disease (ECD), which presented with lesions resembling multiple meningiomas. The patient was initially evaluated for migraine headaches. Initial MR imaging demonstrated a parasellar mass and a second mass near the torcula considered to represent meningiomas. Within 1 year, he developed bilateral orbital lesions surrounding both optic nerves, which were also considered meningiomas. Biopsy of one orbital mass revealed a non-Langerhans histiocytosis. Subsequently, soft tissue masses, a pericardial effusion, and bone lesions consistent with ECD were identified.  (+info)

Erdheim-Chester disease: MR imaging, anatomic, and histopathologic correlation of orbital involvement. (3/34)

Erdheim-Chester disease (ECD) is a rare form of histiocytosis of unknown origin characterized by tissue infiltration by lipid-laden histiocytes. Typically, the diaphyseal and metaphyseal portions of the tubular bones are affected, leading to a characteristic radiographic pattern of bone sclerosis. Orbital involvement is not infrequent and is manifested by exophthalmos and periorbital xanthomatous lesions, with associated visual problems. This case report documents imaging and pathologic findings in a patient with ECD with extensive orbital involvement.  (+info)

Erdheim-Chester disease: case report with multisystemic manifestations including testes, thyroid, and lymph nodes, and a review of literature. (4/34)

Erdheim-Chester disease is a rare non-Langerhans' cell histiocytosis with characteristic radiological and histological features. This entity is defined by a mononuclear infiltrate consisting of lipid laden, foamy histiocytes that stain positively for CD68. About half of those affected have extraskeletal manifestations, including involvement of the hypothalamus-pituitary axis, lung, heart, retroperitoneum, skin, liver, kidneys, spleen, and orbit. This report describes the case of a 50 year old white man who presented with hypogonadism and diabetes insipidus. At necropsy, extensive organ involvement was found, including the testes, thyroid, and lymph nodes. This is the first report of thyroid and lymph node infiltration in this disease. Because of the endocrinological symptoms, neurosarcoidosis and hypophysitis are important diseases in the differential diagnosis. This report also includes a review of the literature concerning rare organ manifestations and patients presenting primarily with similar symptoms.  (+info)

Intradural spinal vein enlargement in craniospinal hypotension. (5/34)

We present a case of craniospinal hypotension in a 45-year-old woman with an associated epidural pseudomeningocele extending the entire length of the spine. The epidural pseudomeningocele was caused by a CSF leak at the T8 level. In addition to typical low-pressure symptoms, the epidural pseudomeningocele caused atypical symptoms characterized by positional thoracic radiculopathy. Craniospinal hypotension was associated with massive cervical epidural venous engorgement, as well as enlargement of the posterior spinal cord vein, which was reminiscent of a dural arteriovenous fistula at CT myelography. Enlargement of the posterior spinal vein is explained by the Monro-Kellie hypothesis, and the spinal analog to enlarged cerebral veins known to be associated with intracranial hypotension.  (+info)

Successful treatment of Erdheim-Chester disease, a non-Langerhans-cell histiocytosis, with interferon-alpha. (6/34)

Erdheim-Chester disease is a rare non-Langerhans histiocytosis with multisystem involvement. To date, there is no standard treatment for this disorder, and more than half of the patients succumb within 3 years. Because interferon-alpha promotes the terminal differentiation of histiocytes and dendritic cells, we hypothesized that this molecule would be a useful therapy for Erdheim-Chester disease. We therefore treated 3 patients with advanced disease with interferon-alpha at a starting dose of 3 to 6 x 10(6) units, which was later reduced, during maintenance, to 1 x 10(6) units subcutaneous 3 times per week. Marked improvement was noted in all patients, with substantial retro-orbital disease regression within 1 month. Improvement in bone lesions, pain, diabetes insipidus, and other manifestations was gradual over many months. Responses were durable (3+ to 4.5+ years). Our observations suggest that this well-tolerated therapy has a significant effect on the course and outcome of Erdheim-Chester disease.  (+info)

Diagnostic value of blind synovial biopsy in clinical practice. (7/34)

OBJECTIVE: To assess the diagnostic value of blindly performed synovial biopsies in carefully selected patients with unclassified arthritis. METHODS: Synovial tissue was obtained blindly under local anaesthesia. The Arthroforce III take-apart 3.5 mm needle and 1.5 mm grasping forceps were used for this purpose. RESULTS: Four patients with unclassified arthritis could be diagnosed properly based upon examination of synovial tissue of the knee obtained by an easy-to-perform blind biopsy. The arthritis of the four patients was diagnosed as being part of Erdheim-Chester disease, sarcoidosis, multicentric reticulohistiocytosis and arthritis caused by foreign-body material, respectively. CONCLUSIONS: Analysis of synovial tissue obtained during a blind biopsy procedure has diagnostic potential in carefully selected patients with unclassified arthritis. The common denominator in all the cases presented was a differential diagnosis consisting of a rheumatological disease with characteristic histological features.  (+info)

Pleural thickening in a construction worker: it is not always mesothelioma. (8/34)

We describe the case of a 45-year-old man presenting with chest pain and pleural effusions. These symptoms were progressive over a period of three years, with pericardial involvement and respiratory insufficiency finally resulting in death. Despite repeated diagnostic procedures, a final diagnosis could only be made at autopsy. Multisystem foamy histiocyte infiltration suggested the diagnosis of Erdheim-Chester disease.  (+info)

I'm sorry for any confusion, but "frozen foods" is not a term that has a specific medical definition. It generally refers to food that has been frozen and preserved at low temperatures. While there may be some medical concerns related to the consumption of certain types of frozen foods (such as those high in sodium or fat), it's not a term that would be used within a medical context. If you have any questions about the safety or nutritional content of specific frozen foods, I'd recommend consulting with a healthcare provider or a nutritionist.

"Swine" is a common term used to refer to even-toed ungulates of the family Suidae, including domestic pigs and wild boars. However, in a medical context, "swine" often appears in the phrase "swine flu," which is a strain of influenza virus that typically infects pigs but can also cause illness in humans. The 2009 H1N1 pandemic was caused by a new strain of swine-origin influenza A virus, which was commonly referred to as "swine flu." It's important to note that this virus is not transmitted through eating cooked pork products; it spreads from person to person, mainly through respiratory droplets produced when an infected person coughs or sneezes.

"Erdheim-Chester Disease". ECD Global Alliance. Retrieved 2009-05-08. "Erdheim Chester disease". NORD (National Organization for ... "Erdheim-Chester Disease Declared a Histiocytic Neoplasm" (PDF). 18 May 2016. Retrieved 2018-07-18 - via erdheim-chester.org. " ... Erdheim-Chester disease (ECD) is an extremely rare disease characterized by the abnormal multiplication of a specific type of ... "Erdheim-Chester disease". Current Rheumatology Reports. 16 (4): 412. doi:10.1007/s11926-014-0412-0. PMID 24532298. Chester W ( ...
See Erdheim-Chester disease Walker, Christopher et al. "Tumorlike conditions of the pleura." RadioGraphics 32 (2012): 971-985. ... diffuse pulmonary lymphangiomatosis and Erdheim-Chester disease. Exposure to asbestos fibers reach the pleura of the lungs ... cirrhosis or chronic kidney disease. On radiological studies, a pleural pseudotumor is visualized as a biconcave or lenticular ...
Attwooll died of Erdheim-Chester disease in 2016. He was survived by his wife of 37 years, Trish Cowan Attwooll, and their ... Deaths from skeletal disease, 20th-century English businesspeople). ...
"Erdheim-Chester disease: a comprehensive review of the literature". Orphanet Journal of Rare Diseases. 8: 137. doi:10.1186/1750 ... In Erdheim-Chester disease, cells of the immune system called histiocytes proliferate at an abnormal rate causing a plethora of ... The hypophyseal portal system also plays an important role in several diseases involving the pituitary and central nervous ...
Jakob Erdheim (1874-1937), Austrian pathologist (see Erdheim-Chester disease). James Ewing (1866-1943), American surgical ... William Boog Leishman (1865-1926), English authority on the pathology of human parasitic diseases (see leishmaniasis) George ... Franz Best (1878-1920), German pathologist (see Best's disease). Xavier Bichat (1771-1802), French anatomist and physiologist, ... Adolf Weil (1848-1916), German physician and pathologist (see Weil's disease). Ronald S. Weinstein (1938-2021), American ...
Erdheim-Chester disease. Shamim Ara, 78, Pakistani actress and director. Alan Bates, 71, American physician and politician, ... Ricci Martin Dies: Entertainer & Youngest Son Of Dean Martin Was 62 Shakira was never slave to her disease. Robert Rosencrans, ... Shakira Martin, 30, American-born Jamaican model and beauty queen, Miss Jamaica Universe (2011), sickle-cell disease. Robert ... Thomas Steinbeck, 72, American writer and war photographer, chronic obstructive pulmonary disease. Sir Ian Turbott, 94, New ...
He is credited with the characterization (or partial characterization) of Erdheim-Chester disease and cystic medial necrosis. ... Erdheim disease: a synonym for cystic medial necrosis. Erdheim tumor: a synonym for craniopharyngioma. He used the term " ... Paget's disease and pituitary gland abnormalities. His name is associated with "Erdheim's syndrome", a condition that is also ... Der wissenschaftliche Werdegang von Professor Jakob Erdheim Jakob Erdheim @ Who Named It The Orthopaedic Journal Our debt to ...
"FDA approves first treatment for certain patients with Erdheim-Chester disease, a rare blood cancer". U.S. Food and Drug ... approved vemurafenib for the treatment of people with Erdheim-Chester disease (ECD), a rare type of histiocytic neoplasm. A ... "Vemurafenib for BRAF V600-Mutant Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Analysis of Data From the Histology ...
Multicentric reticulohistiocytosis Rosai-Dorfman disease Xanthoma disseminatum Kikuchi disease Erdheim-Chester disease. "Non- ... a variant form of Erdheim-Chester disease". Arch. Pathol. Lab. Med. 129 (2): e39-43. doi:10.5858/2005-129-e39-FMNCHP. PMID ... The Genetic and Rare Diseases Information Center (GARD). Retrieved 19 March 2019. Weitzman S, Jaffe R (September 2005). " ...
Dacryoadenitis Erdheim-Chester disease Mucormycosis Orbital pseudotumor - presents with acute, usually unilateral proptosis ... Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor ... In the case of Graves' disease, the displacement of the eye results from abnormal connective tissue deposition in the orbit and ... Gelatt, Kirk (2002). Treatment of Orbital Diseases in Small Animals. Proceedings of the 27th World Congress of the World Small ...
House then orders his team to perform the final test on the first disease suggested: Erdheim-Chester disease. In dismay, the ... House first suspects it is Erdheim-Chester disease and orders a colonoscopy, but tests are negative. House, knowing the next ... He realizes that the disease also remained a secret until the end because they biopsied the colon before the disease had ... Wilson suggests Kawasaki disease, but before the team begins tests, they discover a mass in his heart. Postulating that Ian, ...
... including Erdheim-Chester disease and Langerhans cell histiocytosis. Following EMA approval of cladribine tablets for the ... to include relapsing-remitting disease and active secondary progressive disease, in adult patients who have had an inadequate ... A meta-analysis of data from clinical trials comparing the risk of cancer and other disease-modifying therapies showed that ... No pharmaceutical companies were interested in selling the drug because hairy cell leukemia was an orphan disease, so Beutler's ...
... geneticist Jakob Erdheim, pathologist (Erdheim-Chester disease). Eric Kandel, neuroscientist, winner of 2000 Nobel Prize in ... "Jakob Erdheim". www.1133.at. Archived from the original on 2017-11-14. Retrieved 2017-11-14. "Dr Koller, discoverer of cocaine ...
... pituitary diseases, granulomatous disorders, cerebral Erdheim-Chester disease, lymphomas, metastasis, hemangiopericytomas, ...
... mucinous histiocytosis Reticulohistiocytosis Indeterminate cell histiocytosis Sea-blue histiocytosis Erdheim-Chester disease X- ... 2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6. v t e (Articles with ...
Erdheim-Chester disease (a non-Langerhans-cell histiocytosis) and ameloblastoma. The mechanism of the mutation is that the ...
... dendritic cell sarcoma Fibroblastic reticular cell tumour Disseminated juvenile xanthogranuloma Erdheim-Chester disease ... of undetermined significance Heavy chain diseases Mu heavy chain disease Gamma heavy chain disease Alpha heavy chain disease ... In general, a bone marrow biopsy is part of the "work up" for the analysis of these diseases. All specimens are examined ... Infectious respiratory disease in non-HIV immunocompromised patients. Jose RJ1, Dickey BF, Brown JS. PMID: 25488531 doi: ...
Erdheim-Chester disease Extrinsic allergic alveolitis Factitious disease Fire-eater's lung Fraudulent fever Gaucher's disease ... Thromboembolic disease (i.e. pulmonary embolism, deep venous thrombosis) occasionally shows fever. Although infrequent, its ... Rheumatoid arthritis or adult-onset Still's disease have mixed features and are common causes of FUO. Although most neoplasms ... and amyloidosis Fabry disease Familial cold urticaria Familial Mediterranean fever Hyperimmunoglobulinemia D and periodic fever ...
Epidermal nevus syndrome Epilepsy syndromes Episodic dyscontrol syndrome Epizootic ulcerative syndrome Erdheim-Chester disease ... Town Lawrence-Seip syndrome Lazarus syndrome Leaky gut syndrome Legg-Calvé-Perthes disease Legius syndrome Leiner's disease ... VIP syndrome VIPoma Visual looming syndrome Vitreous touch syndrome Vogt-Koyanagi-Harada disease Von Hippel-Lindau disease ... disease MEDNIK syndrome Megavitamin-B6 syndrome Meige's syndrome Meigs' syndrome MELAS syndrome Melkersson-Rosenthal syndrome ...
Epstein barr virus mononucleosis Epstein syndrome Equinophobia Erb-Duchenne palsy Erdheim disease Erdheim-Chester disease ... This is a list of diseases starting with the letter "E". Diseases Alphabetical list 0-9 A B C D E F G H I J K L M N O P Q R S T ... U V W X Y Z See also Health Exercise Nutrition Ebola virus disease Echovirus infection Ectodermal dysplasia absent ... fibroelastosis Endomyocardial fibrosis Enetophobia Eng-Strom syndrome Engelhard-Yatziv syndrome Englemann disease Enolase ...
... members of the Ptolemaic dynasty likely suffered from a multi-organ fibrotic condition such as Erdheim-Chester disease or a ... Familial Graves' disease could explain the swollen necks and eye prominence (exophthalmos), although this is unlikely to occur ...
9.1.2.4 T-cell and NK/T-cell lymphomas 9.2 Histiocytic tumors 9.2.1 Erdheim-Chester disease 9.2.2 Rosai-Dorfman disease 9.2.3 ... Lhermitte-Duclos disease) 1.5.12 Central neurocytoma 1.5.13 Extraventricular neurocytoma 1.5.14 Cerebellar liponeurocytoma 1.6 ...
Erdheim-Chester disease, lipoid proteinosis (Urbach-Wiethe disease), and the syndrome of adult-onset asthma and periocular ...
... tumors including glioblastoma and pleomorphic xanthoastrocytoma as well as inflammatory diseases like Erdheim-Chester disease. ... Mutations in the BRAF gene can cause disease in two ways. First, mutations can be inherited and cause birth defects. Second, ... Inherited mutations in this gene cause cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental ...
... erdheim-chester disease MeSH C15.604.667.400.410.450 - histiocytosis, sinus MeSH C15.604.667.400.410.575 - lymphohistiocytosis ... hemoglobin sc disease MeSH C15.378.420.155.668 - sickle cell trait MeSH C15.378.420.463 - hemoglobin c disease MeSH C15.378. ... hemorrhagic disease of newborn MeSH C15.378.463.920 - von willebrand disease MeSH C15.378.463.950 - waterhouse-friderichsen ... heavy chain disease MeSH C15.378.147.780.490.512 - immunoproliferative small intestinal disease MeSH C15.378.147.780.650 - ...
Paget's disease of bone, myelofibrosis (primary disorder or secondary to intoxication or malignancy), Erdheim-Chester disease, ... Osteopetrosis, literally "stone bone", also known as marble bone disease or Albers-Schönberg disease, is an extremely rare ... Laurel Burch Lil Bub "Marble Bone Disease: A Review of Osteopetrosis and Its Oral Health Implications for Dentists". Cda-adc.ca ... Lam DK, Sándor GK, Holmes HI, Carmichael RP, Clokie CM (2007). "Marble bone disease: a review of osteopetrosis and its oral ...
... a type of social dance Equine Cushing's disease Erdheim-Chester disease Expanded criteria donor, a class of organ donors ...
Guillaume-Benjamin-Amand Duchenne de Boulogne Erdheim-Chester disease - Jakob Erdheim, William Chester Evans syndrome - R. S. ... Begbie disease, Flajan disease, Flajani-Basedow syndrome, Graves disease, Graves-Basedow disease, Marsh disease, Morbus Basedow ... Disease naming structures which reference place names (such as Bornholm disease, Lyme disease, and Ebola virus disease) are ... examples being Lou Gehrig disease, Hartnup disease, and Mortimer disease. In one instance, Machado-Joseph disease, the eponym ...
"Erdheim-Chester Disease". ECD Global Alliance. Retrieved 2009-05-08. "Erdheim Chester disease". NORD (National Organization for ... "Erdheim-Chester Disease Declared a Histiocytic Neoplasm" (PDF). 18 May 2016. Retrieved 2018-07-18 - via erdheim-chester.org. " ... Erdheim-Chester disease (ECD) is an extremely rare disease characterized by the abnormal multiplication of a specific type of ... "Erdheim-Chester disease". Current Rheumatology Reports. 16 (4): 412. doi:10.1007/s11926-014-0412-0. PMID 24532298. Chester W ( ...
Erdheim-Chester Disease. J.C. Benson, R. Vaubel, B.A. Ebne, I.T. Mark, M. Peris Celda, C.C. Hook, W.O. Tobin and C. Giannini ... Erdheim-Chester disease: misdiagnosed as multiple sclerosis. Jason Yang, Louise Imlay-Gillespie, Judith Gerarda Dierkes, Tien ... Progressive Changes in Cerebral Apparent Diffusion Values in Fabry Disease: A 5-Year Follow-up MRI Study ... Erdheim-Chester Disease. J.C. Benson, R. Vaubel, B.A. Ebne, I.T. Mark, M. Peris Celda, C.C. Hook, W.O. Tobin, C. Giannini ...
Neuroendocrine manifestations are common in Erdheim-Chester disease (ECD) patients. ECD is a rare non-Langerhans form of ...
... confirming the diagnosis of Erdheim-Chester disease (ECD).. The patients clinical management involved several treatments and ...
Hand-ShĂĽller-Christian disease, Letterer-Siwe disease, and eosinophilic granuloma. Erdheim-Chester disease differs from ... Erdheim-Chester disease is a rare multisystemic xanthogranulomatous infiltrative disease of unknown aetiology, due to ... Erdheim-Chester disease is a rare, non-Langerhans form of systemic histiocytosis of unknown aetiology.1 It is associated with ... 1995) Erdheim-Chester disease and slowly progressive cerebellar dysfunction. J Neurol Neurosurg Psychiatry 58:238-240. ...
Erdheim-Chester disease. At least one mutation in the BRAF gene has been identified in some people with Erdheim-Chester disease ... Does the BRAF(V600E) mutation herald a new treatment era for Erdheim-Chester disease? A case-based review of a rare and ... Campochiaro C, Tomelleri A, Cavalli G, Berti A, Dagna L. Erdheim-Chester disease. Eur J Intern Med. 2015 May;26(4):223-9. doi: ... Haroche J, Arnaud L, Cohen-Aubart F, Hervier B, Charlotte F, Emile JF, Amoura Z. Erdheim-Chester disease. Curr Rheumatol Rep. ...
... Medical and Health Sleep Apnea. My Erdheim-Chester Disease - Mucous from the right eye. Gary Stark ... Erdheim-Chester Disease Medical and Health. Erdheim-Chester Disease - Typical presentation. Gary Stark December 12, 2020. ... Erdheim-Chester Disease Medical and Health. Floppy Eyelid Syndrome - sleeping while wearing swimming goggles. Gary Stark ... bluetooth Bluetooth Headset camera Cellphone Cell phone cybercrime cybersecurity digital camera ECD Erdheim-Chester Disease ...
The Erdheim Chester Disease: Case Report and Literature Overview Europ Radiol 1999; 9:153-158 ... The Erdheim Chester Disease: Case Report and Literature Overview. von A. Stäbler , Feb 12, 1999 ... The Erdheim Chester Disease: Case Report and Literature Overview. Europ Radiol 1999; 9:153-158 ...
Erdheim-Chester disease. Haroche J, Arnaud L, Cohen-Aubart F, Hervier B, Charlotte F, Emile JF, Amoura Z. Haroche J, et al. ... Erdheim-Chester disease. Haroche J, Arnaud L, Cohen-Aubart F, Hervier B, Charlotte F, Emile JF, Amoura Z. Haroche J, et al. ... Erdheim-Chester disease]. Haroche J, Cohen-Aubart F, Arnaud L, Hervier B, Charlotte F, Drier A, Gorochov G, Grenier PA, Cluzel ... Cardiovascular outcome in adult-onset Kawasaki disease. Peter E, Fraison JB, Harbaoui B, Paut IK, Dauphin C, Gomard-Mennesson E ...
Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era. Lookup NU ... 2020 by The American Society of Hematology.Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized ... ECD consensus guidelines were published in 2014 on behalf of the physicians and researchers within the Erdheim-Chester Disease ... Most patients with ECD require treatment, except for a minority of patients with minimally symptomatic single-organ disease. ...
Erdheim-Chester disease. HL is characterized by the presence of Reed-Sternberg (RS) cells, and the subtype diagnosis depends on ... Treatment for NHL is based on the type of disease and involves combination therapy or targeted therapies derived from the ... CT scanning of the head and neck (mandatory for a head and neck presentation; localized disease; or cranial neuropathies, ... Stage III or IV disease - Combination chemotherapy (eg, ABVD - which is standard and has more tolerable side effects), more ...
Erdheim Chester Disease. *Mast cell leukemia. *Mastocytosis. $10,000. Fully subscribed and closed to enrollment. Chronic ... The LLS mission: Cure leukemia, lymphoma, Hodgkin disease and myeloma, and improve the quality of life of patients and their ...
Erdheim-Chester disease (ECD), a rare form of non-Langerhans histiocytosis, is a multisystem disorder. The case reported here ... Incidental Diagnosis of Oligosymptomatic Bilateral Perirenal Erdheim-Chester Disease durin Incidental Diagnosis of ... Oligosymptomatic Bilateral Perirenal Erdheim-Chester Disease during Emergency Investigation for COVID-19 Infection. ...
Erdheim-Chester disease: Imaging spectrum of multisystemic manifestations. Amos Hui Sheng Tan and others ... Erdheim-Chester disease: Imaging spectrum of multisystemic manifestations. Amos Hui Sheng Tan and others ... Mental Health Strategies to Combat the Psychological Impact of Coronavirus Disease.... Cyrus SH Ho, Cornelia YI Chee, Roger CM ...
Castlemans Disease. • Diffuse Idiopathic Neuroendocrine Cell Hyperplasia. • Benign Metastasizing Leiomyoma. • Erdheim-Chester ... Rare Lung Disease Program Mission. The Rare Lung Disease Programs mission is to provide state of the art collaborative ... As part of the Rare Lung Disease Clinic Network and member of the Rare Lung Disease Consortium, this program collaborates in ... This program exists to better understand rare lung diseases, train physicians to more completely treat rare lung diseases, and ...
Prevalence of Hypothyroidism in Patients With Erdheim-Chester Disease.. Shekhar S, Sinaii N, Irizarry-Caro JA, Gahl WA, Estrada ... Acting Section Chief: Thyroid Tumors and Functional Thyroid Disorders, Metabolic Diseases Branch ... Do patients with familial nonmedullary thyroid cancer present with more aggressive disease? Implications for initial surgical ...
Erdheim-Chester Disease: The Importance of Information Integration Case Rep Oncol (July,2017) ... Triple-negative breast cancer is regarded as the most aggressive breast malignancy, which contributes to worse disease-free ... leading to progressive disease (PD). Biopsy of pulmonary nodules showed lung metastasis of BC. The patient received vinorelbine ... The patient achieved 10 months of disease-free survival and 7 months of PFS after first-line chemotherapy, suggesting that the ...
A Rare Presentation of Erdheim-Chester Disease Overlaped with Langerhans Histiocytosis (Articles) ... Evaluation of the Quality of Life in Pre- and Post-Operatory in Patients Submitted to Surgical Treatment of Reflux Disease and ...
Erdheim-Chester Disease in a 48-Year-Old Woman with "an Unknown Tumor of the Heart": An Autopsy Report. Lynggård, L. A., ... 2020, I: Blood Cells, Molecules and Diseases. 83, 102440.. Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning ...
Erdheim-Chester disease : diffusion-weighted imaging and dynamic contrast-enhanced MRI provide useful information Thomas Van ...
Erdheim-Chester disease. ND. Rosai-Dorfman disease. ND. Juvenile xanthogranuloma. ND. Langerhans cell histiocytosis ... one tumor entity could develop into another tumor entity with a different grade over the course of disease progression. [1] ...
Erdheim-Chester disease: clinical and radiological findings.. M De Filippo, A Ingegnoli, A Carloni, E Verardo, N Sverzellati, M ... The role of transbronchial lung biopsy for the diagnosis of diffuse drug-induced lung disease: a case series of 44 patients.. M ... Idiopathic nonspecific interstitial pneumonia: an interstitial lung disease associated with autoimmune disorders?. M Romagnoli ...
Roverano S, Gallo J, Ortiz A, Migliore N, Eletti M, Paira S. Erdheim-Chester disease: description of eight cases. Clin ... IgG4-related disease has a 2:1 male preponderance, and the median age of affected patients at diagnosis is in the sixth to ... IgG4-related disease: what a hematologist needs to know. Haematologica. 2019 Mar. 104 (3):444-455. [QxMD MEDLINE Link]. [Full ... Adam U, Mack D, Forstner R, Fritzenwallner A, Frick J. Conservative treatment of acute Ormonds disease. Tech Urol. 1999 Mar. 5 ...
Roverano S, Gallo J, Ortiz A, Migliore N, Eletti M, Paira S. Erdheim-Chester disease: description of eight cases. Clin ... IgG4-related disease: what a hematologist needs to know. Haematologica. 2019 Mar. 104 (3):444-455. [QxMD MEDLINE Link]. [Full ... Adam U, Mack D, Forstner R, Fritzenwallner A, Frick J. Conservative treatment of acute Ormonds disease. Tech Urol. 1999 Mar. 5 ... IgG4-related retroperitoneal fibrosis: a newly characterized disease. Int J Rheum Dis. 2016 Apr 29. [QxMD MEDLINE Link]. ...
... is a rare lung disease which causes lung cysts to form. Find out more about symptoms and causes. ... Also included in this group are more rare diseases, juvenile xanthogranuloma (JXG) and Erdheim Chester. ... What is an orphan disease? According to the Rare Disease Act of 2002, an orphan disease, also known as a rare disease, affects ... How many orphan diseases are there? According to the National Institutes of Health there are approximately 6800 such diseases. ...
Erdheim-Chester Disease (ECD), Rosai-Dorfman Disease (RDD), Juvenile Xanthogranuloma (JXG), and Histiocytic Sarcoma (HS). ... The ECD Global Alliance (ECDGA) is dedicated to awareness, support, education, and research related to Erdheim-Chester Disease ... Rare Disease Resource Guide For Caregivers. 2021 rare disease resource guide for caregivers published by Global Genes. Its ... Dedicated to promoting scientific research to uncover the causes of histiocytic diseases and ensure early diagnosis, effective ...
Case 245: Erdheim-Chester Disease. Radiology. 2017 09; 284(3):910-917. Mamlouk MD, Aboian MS, Glastonbury CM. PMID: 28825890. ... Lastly, he is interested in revolutionizing radiology reporting to make it more tailored to specific diseases. ...
Erdheim-Chester disease and Langerhans cell histiocytosis; ref. 13). Expanded enrollment of patients with Erdheim-Chester ... Vemurafenib for BRAF V600-mutant Erdheim-Chester disease and Langerhans cell histiocytosis: analysis of data from the histology ... FDA approval summary: vemurafenib for the treatment of patients with Erdheim-Chester disease with the BRAFV600 mutation ... data from this study were used to support approval of vemurafenib in the histiocytic neoplasm Erdheim-Chester disease in the ...
IgG4-Related Disease - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical ... Erdheim-Chester disease. *. Lymphadenopathy: Sarcoidosis Sarcoidosis Sarcoidosis is an inflammatory disorder resulting in ... Interstitial lung disease Overview of Interstitial Lung Disease Interstitial lung diseases are a heterogeneous group of ... Rosai-Dorfman disease Rosai-Dorfman Disease Rosai-Dorfman disease is a rare disorder characterized by an abnormal accumulation ...
  • Erdheim-Chester disease (ECD) is an extremely rare disease characterized by the abnormal multiplication of a specific type of white blood cells called histiocytes, or tissue macrophages (technically, this disease is termed a non-Langerhans-cell histiocytosis). (wikipedia.org)
  • Langerhans cell histiocytosis (LCH) is blood disease which is now recognized as a cancer and can affect virtually any organ system of the body. (histio.org)
  • The Memorial Sloan Kettering Make-an-IMPACT Initiative is a rare-cancer global outreach initiative that provides free genomic profiling for patients with Langerhans Cell Histiocytosis (LCH), Erdheim-Chester Disease (ECD), Rosai-Dorfman Disease (RDD), Juvenile Xanthogranuloma (JXG), and Histiocytic Sarcoma (HS). (histio.org)
  • solid course="kwd-title" Keywords: Erdheim Chester Disease, Langerhans cell histiocytosis, Cladribine, Treatment 1. (bioskinrevive.com)
  • Launch Erdheim Chester Disease (ECD) is a rare non-Langerhans cell histiocytosis. (bioskinrevive.com)
  • Oral MEK1/2 inhibitor cobimetinib (Cotellic) has received approval by the FDA for the treatment of patients with histiocytic neoplasms including Erdheim-Chester disease, Rosai-Dorfman disease, and Langerhans cell histiocytosis. (cancernetwork.com)
  • They include Langerhans cell histiocytosis, Erdheim-Chester disease, and Rosai-Dorfman disease. (ucsd.edu)
  • No consensus exists for the optimal therapy for Langerhans cell histiocytosis (LCH), particularly in the case of multisystem organ disease. (medscape.com)
  • The presence of symmetrical cerebellar and pontine signal changes on T2-weighted images seem to be typical of ECD, however, multiple sclerosis and metabolic diseases must also be considered in the differential diagnosis. (wikipedia.org)
  • In 2019, the Mayo Clinic published guidelines for the diagnosis and treatment of the disease, stressing the importance of genetic testing: "Recent insights into their genomic architecture demonstrating mitogen-activated protein kinase/extracellular signal-regulated kinase pathway mutations have now enabled potential treatment with targeted therapies in most patients. (wikipedia.org)
  • Genetic analysis of histopathological samples detected a V600E or V600Ec missense variant within codon 600 of the BRAF genewith BRAF variants, confirming the diagnosis of Erdheim-Chester disease (ECD). (bmj.com)
  • In 1994, after three years of progressive neurological dysfunction, diagnosis of Erdheim-Chester disease was made by analysis of biopsies of the femur bones, showing infiltration with foamy histiocytes lacking Birbeck granules and S-100 protein, and with few lymphocytes. (bmj.com)
  • Incidental Diagnosis of Oligosymptomatic Bilateral Perirenal Erdheim-Chester Disease during Emergency Investigation for COVID-19 Infection. (bvsalud.org)
  • The role of transbronchial lung biopsy for the diagnosis of diffuse drug-induced lung disease: a case series of 44 patients. (google.it)
  • Biopsy and histologic/immunohistochemical examination of the affected tissue can aid in the diagnosis and determination of the extent of the disease, which in turn affect treatment management strategies. (medscape.com)
  • Optimal care in patients with RPF requires an integrated approach of surgical and nonsurgical therapies, and depends on the stage of the disease at diagnosis. (medscape.com)
  • Dedicated to promoting scientific research to uncover the causes of histiocytic diseases and ensure early diagnosis, effective treatment and a cure. (histio.org)
  • His major clinical and research interests concern the diagnosis and management of diseases affecting the aorta and its major branches. (sc-ctsi.org)
  • Genotyping of 69 histiocytic lesions revealed that 23/48 Langerhans cell lesions were BRAF -V600E-mutant whereas all non-Langerhans cell lesions (including dendritic cell sarcoma, juvenile xanthogranuloma, Rosai-Dorfman disease, and granular cell tumor) were wild-type. (oncotarget.com)
  • Neuroendocrine manifestations of Erdheim-Chester disease. (iasp-pain.org)
  • Neuroendocrine manifestations are common in Erdheim-Chester disease (ECD) patients. (iasp-pain.org)
  • The clinical manifestations of the currently recognized disease entities are highly variable and range from benign localized lesions to highly aggressive systemic diseases[ 4 ]. (oncotarget.com)
  • Blueberry muffin baby" is a term describing the cutaneous manifestations of various congenital infections and neoplastic diseases. (thieme-connect.de)
  • Erdheim-Chester disease is a rare, non-Langerhans form of systemic histiocytosis of unknown aetiology. (bmj.com)
  • The clinical picture ranges from focal bone lesions to systemic disease with life threatening visceral involvement. (bmj.com)
  • Effects of casirivimab/imdevimab on systemic and mucosal immunity against SARS-CoV-2 in B-cell depleted patients with autoimmune rheumatic diseases refractory to vaccination. (uk-erlangen.de)
  • Systemic chemotherapy is indicated for multisystem disease and cases of single-system disease not responsive to other treatment. (medscape.com)
  • If you believe the bulletins put out by the American College of Rheumatology, we have pretty much conquered all of the well-known rheumatic conditions and are now simply investigating the really uncommon ones, such as Erdheim-Chester disease or systemic capillary leak syndrome ( The Rheumatologist , February 2017 and December 2016 ). (medscape.com)
  • At least one mutation in the BRAF gene has been identified in some people with Erdheim-Chester disease. (medlineplus.gov)
  • This mutation leads to production of a BRAF protein that is abnormally active, which disrupts regulation of cell proliferation and may allow histiocytes to grow and divide uncontrollably, leading to the abnormal accumulation of histiocytes that occurs in Erdheim-Chester disease. (medlineplus.gov)
  • Lung involvement in LCH can occur alone (single-system PLCH) or as multi-system disease (where it involves more than one organ system). (histio.org)
  • They further categorize those cases with single-system involvement by the number of sites within that system (eg, monostotic vs polyostotic bone disease, solitary vs multiple lymph node involvement). (medscape.com)
  • Psoralen plus ultraviolet A (PUVA) is another effective modality for cutaneous-only LCH or for cutaneous involvement in multisystemic disease. (medscape.com)
  • The intermediate clinical form called Hand-SchĂĽller-Christian disease is characterized by multifocal, chronic involvement and classically presents as the triad of diabetes insipidus, proptosis, and lytic bone lesions. (medscape.com)
  • The disease involves an infiltration of lipid-laden macrophages, multinucleated giant cells, an inflammatory infiltrate of lymphocytes and histiocytes in the bone marrow, and a generalized sclerosis of the long bones. (wikipedia.org)
  • The disease most commonly affects the bones, causing bone thickening and pain, but the accumulation of histiocytes can also cause signs and symptoms affecting the brain, eyes, lungs, liver, kidneys, and other organs. (medlineplus.gov)
  • 2021 rare disease resource guide for caregivers published by Global Genes. (histio.org)
  • Two patients with Erdheim-Chester disease with progressive cerebellar dysfunction and pyramidal signs are reported on. (bmj.com)
  • 3 4 We report on two patients with Erdheim-Chester disease with slowly progressive cerebellar dysfunction, associated with pyramidal symptoms. (bmj.com)
  • Treatment for ECD is normally reserved for all those with symptomatic disease, asymptomatic CNS participation, or proof organ dysfunction. (bioskinrevive.com)
  • This department provides medical care for patients with acute and chronic kidney diseases, kidney failure, dysfunction and tumors of endocrine organs, and hypertension. (japanhospitalsearch.org)
  • The Erdheim-Chester Disease Global Alliance is a support and advocacy group with the goal of raising awareness of and promoting research into ECD. (wikipedia.org)
  • The ECD Global Alliance (ECDGA) is dedicated to awareness, support, education, and research related to Erdheim-Chester Disease. (histio.org)
  • These macrophages portrayed Compact disc68, and Element XIIIa, however, not Compact disc1a, Tofacitinib citrate as can be quality of Erdheim-Chester disease. (bioskinrevive.com)
  • A congenital, self-healing form called Hashimoto-Pritzker disease has also been described. (medscape.com)
  • On one end, the clinical spectrum includes an acute, fulminant, disseminated disease called Letterer-Siwe disease, and, on the other end, solitary or few, indolent and chronic lesions of bone or other organs called eosinophilic granulomas . (medscape.com)
  • This department provides preventive care and treatment for diseases such as diabetes, dyslipidemia, obesity, and metabolic syndrome, which have been proliferating as lifestyles change. (japanhospitalsearch.org)
  • Recent studies have reported that some patients receiving targeted therapies showed no disease progression. (wikipedia.org)
  • The Rare Lung Disease Program's mission is to provide state of the art collaborative evaluation and treatment for patients with rare lung diseases. (uab.edu)
  • Prevalence of Hypothyroidism in Patients With Erdheim-Chester Disease. (nih.gov)
  • Other tests (blood work, ultrasound of the abdomen, PET scan, MRI brain) may be indicated in some patients to understand the extent of disease and whether there is LCH affecting organs other than the lung. (histio.org)
  • It's brimming with advice and resources for caregivers of patients with rare diseases. (histio.org)
  • Nelson J. Chao, MD, MBA, and his colleagues discussed the use of ruxolitinib as treatment for patients with graft-vs-host disease. (cancernetwork.com)
  • Can Pentraxin-3 be a Candidate Marker in the Follow-Up of the Patients With Behçet's Disease? (archivesofrheumatology.org)
  • Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study. (uk-erlangen.de)
  • The LLS mission: Cure leukemia, lymphoma, Hodgkin disease and myeloma, and improve the quality of life of patients and their families. (lls.org)
  • Using sporadic Burkitt lymphoma as our principle disease, we are studying the genetic, transcriptomic and clonal changes which occur in response to therapeutic pressure within patient-derived xenograft models. (ncl.ac.uk)
  • Generally, the choice of therapeutic regimen is based on disease severity. (medscape.com)
  • 2.?Case A 61-year-old previously healthy man with a brief history of progressive exhaustion, decrease extremity edema, and dyspnea for 4 a few months was hospitalized in an outside service and identified as Rabbit Polyclonal to MMP-8 having a pericardial effusion and bilateral pleural effusions (Fig.?1A and B). Lung, pericardial, and pleural biopsies had been in keeping with Erdheim-Chester disease (ECD) (Fig.?3, Fig.?4). (bioskinrevive.com)
  • A recent study published in Nucleus highlighted the impact of graft-vs-host disease prophylaxis on cytomegalovirus reactivation. (cancernetwork.com)
  • As part of the Rare Lung Disease Clinic Network and member of the Rare Lung Disease Consortium, this program collaborates in the development of novel testing and treatments for rare lung diseases. (uab.edu)
  • After the appointment is scheduled, your patient will receive a package containing a schedule of tests and appointments, along with the "UAB Rare Lung Disease Patient Questionnaire," maps, and information on lodging in the Kirklin Clinic area. (uab.edu)
  • Idiopathic nonspecific interstitial pneumonia: an interstitial lung disease associated with autoimmune disorders? (google.it)
  • Treatment for NHL is based on the type of disease and involves combination therapy or targeted therapies derived from the immunohistochemistry of the tumor. (medscape.com)
  • Artificial Intelligence in Coronary Artery Disease Imaging: Has the Future Arrived? (gwu.edu)
  • Immunoglobulin G4-related disease (IgG4-RD) is a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses and/or painless enlargement of multiple organs. (msdmanuals.com)
  • Selection criterion for endovascular aortic repair in those with chronic kidney disease. (sc-ctsi.org)
  • About 10-15% of adults with PLCH will also have symptoms due to disease in organs outside of the chest, for example bone pain or skin rash. (histio.org)
  • This is a national registered charity in the U.K. that provides support and information to families of disabled children, as well as children with rare diseases. (histio.org)
  • Rare Disease PHGKB is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other information that address the public health impact and translation of genomic and other precision health discoveries into improved health outcomes related to rare diseases. (cdc.gov)
  • As such, under the older guidelines, one tumor entity could develop into another tumor entity with a different grade over the course of disease progression. (medscape.com)
  • This program exists to better understand rare lung diseases, train physicians to more completely treat rare lung diseases, and to drive the creation of superior treatment options. (uab.edu)
  • The purpose of this treatment is to induce remission of skin diseases by inducing a repeated and controlled phototoxic reaction. (medscape.com)
  • [ 45 ] A case report on pharmacologic management of single-system bony disease using naproxen indicates that multiple COX antagonists may be used in treating this form of LCH. (medscape.com)
  • Our aim is to deeply characterise paediatric B-cell non-Hodgkin lymphoma to provide a comprehensive understanding of disease initiation and evolution in response to therapy. (ncl.ac.uk)
  • Erdheim-Chester disease: clinical and radiological findings. (google.it)
  • Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. (cdc.gov)
  • [ 3 ] Taken together, these findings have led some to speculate that LCH is not a specific disease of epidermal Langerhans cells, but rather one of mononuclear phagocyte dysregulation. (medscape.com)
  • Blood Cells, Molecules and Diseases. (aau.dk)
  • Single-system PLCH rarely spreads to other organs outside the lungs, but any new symptoms should prompt further investigations into additional sites of disease. (histio.org)