Fatigue
Muscle Fatigue
Fatigue Syndrome, Chronic
Mental Fatigue
Muscle Contraction
Muscle, Skeletal
Isometric Contraction
Quality of Life
Physical Endurance
Severity of Illness Index
Questionnaires
Sleep Disorders
Fibromyalgia
Electromyography
Asthenopia
Depression
Pain
Neoplasms
Torque
Treatment Outcome
Exercise
Diaphragm
Muscle Strength
Physical Exertion
Postpoliomyelitis Syndrome
Neurasthenia
Work Schedule Tolerance
Survivors
Quadriceps Muscle
Sleep
Multiple Sclerosis
Materials Testing
Fractures, Stress
Anxiety
Pain Measurement
Exercise Therapy
Chronic Disease
Disorders of Excessive Somnolence
Stress, Mechanical
Activities of Daily Living
Exercise Tolerance
Biomechanical Phenomena
Perioperative growth hormone treatment and functional outcome after major abdominal surgery: a randomized, double-blind, controlled study. (1/2703)
OBJECTIVE: To evaluate short- and long-term effects of perioperative human growth hormone (hGH) treatment on physical performance and fatigue in younger patients undergoing a major abdominal operation in a normal postoperative regimen with oral nutrition. SUMMARY BACKGROUND DATA: Muscle wasting and functional impairment follow major abdominal surgery. METHODS: Twenty-four patients with ulcerative colitis undergoing ileoanal J-pouch surgery were randomized to hGH (12 IU/day) or placebo treatment from 2 days before to 7 days after surgery. Measurements were performed 2 days before and 10, 30, and 90 days after surgery. RESULTS: The total muscle strength of four limb muscle groups was reduced by 7.6% in the hGH group and by 17.1% in the placebo group at postoperative day 10 compared with baseline values. There was also a significant difference between treatment groups in total muscle strength at day 30, and at the 90-day follow-up total muscle strength was equal to baseline values in the hGH group, but still significantly 5.9% below in the placebo group. The work capacity decreased by approximately 20% at day 10 after surgery, with no significant difference between treatment groups. Both groups were equally fatigued at day 10 after surgery, but at day 30 and 90 the hGH patients were less fatigued than the placebo patients. During the treatment period, patients receiving hGH had reduced loss of limb lean tissue mass, and 3 months after surgery the hGH patients had regained more lean tissue mass than placebo patients. CONCLUSIONS: Perioperative hGH treatment of younger patients undergoing major abdominal surgery preserved limb lean tissue mass, increased postoperative muscular strength, and reduced long-term postoperative fatigue. (+info)Carbon disulphide absorption during xanthate reagent mixing in a gold mine concentrator. (2/2703)
A xanthate reagent mixer at a gold mine concentrator was exposed to carbon disulphide by extensive skin contamination with xanthate powder and solution during the reagent mixing process. Absorption of carbon disulphide was confirmed by the detection of urinary 2-thiothiazolidine-4-carboxylic acid (TTCA). Drager colorimetric tube testing during subsequent mixing recorded a maximum concentration of at least 60 ppm carbon disulphide. An illness consisting of predominantly gastrointestinal symptoms began 20 h after the exposure. Although this may have been due to carbon disulphide toxicity this is by no means certain. The need for engineering controls, impervious protective clothing and full-face respirators with particulate and organic vapour cartridges is discussed. This episode occurred at another mine site, unrelated to Mount Isa Mines Limited. (+info)The role of capsaicin-sensitive muscle afferents in fatigue-induced modulation of the monosynaptic reflex in the rat. (3/2703)
1. The role of group III and IV afferent fibres of the lateral gastrocnemious muscle (LG) in modulating the homonymous monosynaptic reflex was investigated during muscle fatigue in spinalized rats. 2. Muscle fatigue was induced by a series of increasing tetanic electrical stimuli (85 Hz, 600 ms) delivered to the LG muscle nerve. Series consisted of increasing train numbers from 1 to 60. 3. Potentials from the spinal cord LG motor pool and from the ventral root were recorded in response to proprioceptive afferent stimulation and analysed before and during tetanic muscle activations. Both the pre- and postsynaptic waves showed an initial enhancement and, after a '12-train' series, an increasing inhibition. 4. The enhancement of the responses to muscle fatiguing stimulation disappeared after L3-L6 dorsal root section, while a partial reflex inhibition was still present. Conversely, after section of the corresponding ventral root, there was only a reduction in the inhibitory effect. 5. The monosynaptic reflex was also studied in animals in which a large number of group III and IV muscle afferents were eliminated by injecting capsaicin (10 mM) into the LG muscle. As a result of capsaicin treatment, the fatigue-induced inhibition of the pre- and postsynaptic waves disappeared, while the response enhancement remained. 6. We concluded that the monosynaptic reflex inhibition, but not the enhancement, was mediated by those group III and IV muscle afferents that are sensitive to the toxic action of capsaicin. The afferents that are responsible for the response enhancement enter the spinal cord through the dorsal root, while those responsible for the inhibition enter the spinal cord through both the ventral and dorsal roots. (+info)Effect of working hours on cardiovascular-autonomic nervous functions in engineers in an electronics manufacturing company. (4/2703)
A field survey of 147 engineers (23-49 years) in an electronics manufacturing company was conducted to investigate the effect of working hours on cardiovascular-autonomic nervous functions (urinary catecholamines, heart rate variability and blood pressure). The subjects were divided into 3 groups by age: 23-29 (n = 49), 30-39 (n = 74) and 40-49 (n = 24) year groups. Subjects in each age group were further divided into shorter (SWH) and longer (LWH) working hour subgroups according to the median of weekly working hours. In the 30-39 year group, urinary noradrenaline in the afternoon for LWH was significantly lower than that for SWH and a similar tendency was found in the LF/HF ratio of heart rate variability at rest. Because these two autonomic nervous indices are related to sympathetic nervous activity, the findings suggested that sympathetic nervous activity for LWH was lower than that for SWH in the 30-39 year group. Furthermore, there were significant relationships both between long working hours and short sleeping hours, and between short sleeping hours and high complaint rates of "drowsiness and dullness" in the morning in this age group. Summarizing these results, it appeared that long working hours might lower sympathetic nervous activity due to chronic sleep deprivation. (+info)Investigating fatigue of less than 6 months' duration. Guidelines for family physicians. (5/2703)
OBJECTIVE: To develop an evidence-based systematic approach to assessment of adult patients who present to family physicians complaining of fatigue of less than 6 months' duration. The guidelines present investigative options, making explicit what should be considered in all cases and what should be considered only in specific situations. They aim to provide physicians with an approach that, to the extent possible, is based on evidence so that time and cost are minimized and detection and management of the cause of the fatigue are optimized. QUALITY OF EVIDENCE: MEDLINE was searched from 1966 to 1997 using the key words "family practice" and "fatigue." Articles about chronic fatigue syndrome were excluded. Articles with level 3 evidence were found, but no randomized trials, cohort studies, or case-control studies were found. Articles looking specifically at the epidemiology, demographics, investigations, and diagnoses of patients with fatigue were chosen. Articles based on studies at referral and specialty centres were given less weight than those based on studies in family physicians' offices. MAIN MESSAGE: Adherence to these guidelines will decrease the cost of investigating the symptom of fatigue and optimize diagnosis and management. This needs to be proved in practice, however, and with research that produces level 1 and 2 evidence. CONCLUSIONS: Adults presenting with fatigue of less than 6 months' duration should be assessed for psychosocial causes and should have a focused history and physical examination to determine whether further investigations should be done. The guidelines outline investigations to be considered. The elderly require special consideration. These guidelines have group validation, but they need to be tested by more physicians in various locations and types of practices. (+info)Phase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancer. (6/2703)
PURPOSE: To evaluate the feasibility of administering topotecan in combination with paclitaxel and cisplatin without and with granulocyte colony-stimulating factor (G-CSF) support as first-line chemotherapy in women with incompletely resected stage III and stage IV ovarian carcinoma. PATIENTS AND METHODS: Starting doses were paclitaxel 110 mg/m2 administered over 24 hours (day 1), followed by cisplatin 50 mg/m2 over 3 hours (day 2) and topotecan 0.3 mg/m2/d over 30 minutes for 5 consecutive days (days 2 to 6). Treatment was repeated every 3 weeks. After encountering dose-limiting toxicities (DLTs) without G-CSF support, the maximum-tolerated dose was defined as 5 microg/kg of G-CSF subcutaneously starting on day 6. RESULTS: Twenty-one patients received a total of 116 courses at four different dose levels. The DLT was neutropenia. At the first dose level, all six patients experienced grade 4 myelosuppression. G-CSF support permitted further dose escalation of cisplatin and topotecan. Nonhematologic toxicities, primarily fatigue, nausea/vomiting, and neurosensory neuropathy, were observed but were generally mild. Of 15 patients assessable for response, nine had a complete response, four achieved a partial response, and two had stable disease. CONCLUSION: Neutropenia was the DLT of this combination of paclitaxel, cisplatin, and topotecan. The recommended phase II dose is paclitaxel 110 mg/m2 (day 1), followed by cisplatin 75 mg/m2 (day 2) and topotecan 0.3 mg/m2/d (days 2 to 6) with G-CSF support repeated every 3 weeks. (+info)Manganese sulfate-dependent glycosylation of endogenous glycoproteins in human skeletal muscle is catalyzed by a nonglucose 6-P-dependent glycogen synthase and not glycogenin. (7/2703)
Glycogenin, a Mn2+-dependent, self-glucosylating protein, is considered to catalyze the initial glucosyl transfer steps in glycogen biogenesis. To study the physiologic significance of this enzyme, measurements of glycogenin mediated glucose transfer to endogenous trichloroacetic acid precipitable material (protein-bound glycogen, i.e., glycoproteins) in human skeletal muscle were attempted. Although glycogenin protein was detected in muscle extracts, activity was not, even after exercise that resulted in marked glycogen depletion. Instead, a MnSO4-dependent glucose transfer to glycoproteins, inhibited by glycogen and UDP-pyridoxal (which do not affect glycogenin), and unaffected by CDP (a potent inhibitor of glycogenin), was consistently detected. MnSO4-dependent activity increased in concert with glycogen synthase fractional activity after prolonged exercise, and the MnSO4-dependent enzyme stimulated glucosylation of glycoproteins with molecular masses lower than those glucosylated by glucose 6-P-dependent glycogen synthase. Addition of purified glucose 6-P-dependent glycogen synthase to the muscle extract did not affect MnSO4-dependent glucose transfer, whereas glycogen synthase antibody completely abolished MnSO4-dependent activity. It is concluded that: (1) MnSO4-dependent glucose transfer to glycoproteins is catalyzed by a nonglucose 6-P-dependent form of glycogen synthase; (2) MnSO4-dependent glycogen synthase has a greater affinity for low molecular mass glycoproteins and may thus play a more important role than glucose 6-P-dependent glycogen synthase in the initial stages of glycogen biogenesis; and (3) glycogenin is generally inactive in human muscle in vivo. (+info)Fatigue in advanced cancer: a prospective controlled cross-sectional study. (8/2703)
Uncontrolled studies have reported that fatigue is a common symptom among patients with advanced cancer. It is also a frequent complaint among the general population. Simply asking cancer patients whether or not they feel fatigued does not distinguish between the 'background' level of this symptom in the community and any 'excess' arising as a result of illness. The aim of this study was to determine the prevalence of fatigue among palliative care inpatients in comparison with a control group of age and sex-matched volunteers without cancer. In addition, the correlates of fatigue were investigated. The prevalence of 'severe subjective fatigue' (defined as fatigue greater than that experienced by 95% of the control group) was found to be 75%. Patients were malnourished, had diminished muscle function and were suffering from a number of physical and mental symptoms. The severity of fatigue was unrelated to age, sex, diagnosis, presence or site of metastases, anaemia, dose of opioid or steroid, any of the haematological or biochemical indices (except urea), nutritional status, voluntary muscle function, or mood. A multivariate analysis found that fatigue severity was significantly associated with pain and dypnoea scores in the patients, and with the symptoms of anxiety and depression in the controls. The authors conclude that subjective fatigue is both prevalent and severe among patients with advanced cancer. The causes of this symptom remain obscure. Further work is required in order to determine if the associations reported between fatigue and pain and between fatigue and dyspnoea are causal or coincidental. (+info)Fatigue is a state of feeling very tired, weary, or exhausted, which can be physical, mental, or both. It is a common symptom that can be caused by various factors, including lack of sleep, poor nutrition, stress, medical conditions (such as anemia, diabetes, heart disease, or cancer), medications, and substance abuse. Fatigue can also be a symptom of depression or other mental health disorders. In medical terms, fatigue is often described as a subjective feeling of tiredness that is not proportional to recent activity levels and interferes with usual functioning. It is important to consult a healthcare professional if experiencing persistent or severe fatigue to determine the underlying cause and develop an appropriate treatment plan.
Muscle fatigue is a condition characterized by a reduction in the ability of a muscle to generate force or power, typically after prolonged or strenuous exercise. It is often accompanied by sensations of tiredness, weakness, and discomfort in the affected muscle(s). The underlying mechanisms of muscle fatigue are complex and involve both peripheral factors (such as changes in muscle metabolism, ion handling, and neuromuscular transmission) and central factors (such as changes in the nervous system's ability to activate muscles). Muscle fatigue can also occur as a result of various medical conditions or medications that impair muscle function.
Chronic Fatigue Syndrome (CFS) is a complex disorder characterized by extreme fatigue that does not improve with rest and is often worsened by physical or mental activity. The exact cause of CFS remains unknown, although it can be triggered by various factors such as infections, immune system dysfunction, hormonal imbalances, and stress.
The main symptom of CFS is severe fatigue that lasts for six months or longer, which is not relieved by rest and is often accompanied by other symptoms such as:
* Difficulty concentrating or remembering things
* Sore throat
* Swollen lymph nodes in the neck or armpits
* Muscle pain
* Joint pain without redness or swelling
* Headaches of a new type, pattern, or severity
* Unrefreshing sleep
* Extreme exhaustion lasting more than 24 hours after physical or mental exercise
The diagnosis of CFS is based on the patient's symptoms and medical history, as there are no specific diagnostic tests for this condition. Treatment typically focuses on relieving symptoms and improving function through a combination of medications, lifestyle changes, and complementary therapies.
Mental fatigue is not a formally defined medical condition, but it's often used to describe the feeling of being mentally drained or exhausted due to prolonged periods of mental activity or stress. It can be characterized by symptoms such as difficulty concentrating, memory problems, mood changes, and reduced motivation or energy.
While mental fatigue is not a diagnosable medical condition, it can be a symptom of various underlying issues, including sleep disorders, mood disorders, neurological conditions, or other medical problems. If someone is experiencing significant mental fatigue that interferes with their daily functioning, they should consult a healthcare professional for further evaluation and treatment.
Muscle contraction is the physiological process in which muscle fibers shorten and generate force, leading to movement or stability of a body part. This process involves the sliding filament theory where thick and thin filaments within the sarcomeres (the functional units of muscles) slide past each other, facilitated by the interaction between myosin heads and actin filaments. The energy required for this action is provided by the hydrolysis of adenosine triphosphate (ATP). Muscle contractions can be voluntary or involuntary, and they play a crucial role in various bodily functions such as locomotion, circulation, respiration, and posture maintenance.
Skeletal muscle, also known as striated or voluntary muscle, is a type of muscle that is attached to bones by tendons or aponeuroses and functions to produce movements and support the posture of the body. It is composed of long, multinucleated fibers that are arranged in parallel bundles and are characterized by alternating light and dark bands, giving them a striped appearance under a microscope. Skeletal muscle is under voluntary control, meaning that it is consciously activated through signals from the nervous system. It is responsible for activities such as walking, running, jumping, and lifting objects.
Isometric contraction is a type of muscle activation where the muscle contracts without any change in the length of the muscle or movement at the joint. This occurs when the force generated by the muscle matches the external force opposing it, resulting in a balanced state with no visible movement. It is commonly experienced during activities such as holding a heavy object in static position or trying to push against an immovable object. Isometric contractions are important in maintaining posture and providing stability to joints.
Quality of Life (QOL) is a broad, multidimensional concept that usually includes an individual's physical health, psychological state, level of independence, social relationships, personal beliefs, and their relationship to salient features of their environment. It reflects the impact of disease and treatment on a patient's overall well-being and ability to function in daily life.
The World Health Organization (WHO) defines QOL as "an individual's perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns." It is a subjective concept, meaning it can vary greatly from person to person.
In healthcare, QOL is often used as an outcome measure in clinical trials and other research studies to assess the impact of interventions or treatments on overall patient well-being.
Physical endurance is the ability of an individual to withstand and resist physical fatigue over prolonged periods of strenuous activity, exercise, or exertion. It involves the efficient functioning of various body systems, including the cardiovascular system (heart, blood vessels, and blood), respiratory system (lungs and airways), and musculoskeletal system (muscles, bones, tendons, ligaments, and cartilage).
Physical endurance is often measured in terms of aerobic capacity or stamina, which refers to the body's ability to supply oxygen to muscles during sustained physical activity. It can be improved through regular exercise, such as running, swimming, cycling, or weightlifting, that challenges the body's major muscle groups and raises the heart rate for extended periods.
Factors that influence physical endurance include genetics, age, sex, fitness level, nutrition, hydration, sleep quality, stress management, and overall health status. It is essential to maintain good physical endurance to perform daily activities efficiently, reduce the risk of chronic diseases, and enhance overall well-being.
A Severity of Illness Index is a measurement tool used in healthcare to assess the severity of a patient's condition and the risk of mortality or other adverse outcomes. These indices typically take into account various physiological and clinical variables, such as vital signs, laboratory values, and co-morbidities, to generate a score that reflects the patient's overall illness severity.
Examples of Severity of Illness Indices include the Acute Physiology and Chronic Health Evaluation (APACHE) system, the Simplified Acute Physiology Score (SAPS), and the Mortality Probability Model (MPM). These indices are often used in critical care settings to guide clinical decision-making, inform prognosis, and compare outcomes across different patient populations.
It is important to note that while these indices can provide valuable information about a patient's condition, they should not be used as the sole basis for clinical decision-making. Rather, they should be considered in conjunction with other factors, such as the patient's overall clinical presentation, treatment preferences, and goals of care.
A questionnaire in the medical context is a standardized, systematic, and structured tool used to gather information from individuals regarding their symptoms, medical history, lifestyle, or other health-related factors. It typically consists of a series of written questions that can be either self-administered or administered by an interviewer. Questionnaires are widely used in various areas of healthcare, including clinical research, epidemiological studies, patient care, and health services evaluation to collect data that can inform diagnosis, treatment planning, and population health management. They provide a consistent and organized method for obtaining information from large groups or individual patients, helping to ensure accurate and comprehensive data collection while minimizing bias and variability in the information gathered.
Sleep disorders are a group of conditions that affect the ability to sleep well on a regular basis. They can include problems with falling asleep, staying asleep, or waking up too early in the morning. These disorders can be caused by various factors such as stress, anxiety, depression, medical conditions, or substance abuse.
The American Academy of Sleep Medicine (AASM) recognizes over 80 distinct sleep disorders, which are categorized into the following major groups:
1. Insomnia - difficulty falling asleep or staying asleep.
2. Sleep-related breathing disorders - abnormal breathing during sleep such as obstructive sleep apnea.
3. Central disorders of hypersomnolence - excessive daytime sleepiness, including narcolepsy.
4. Circadian rhythm sleep-wake disorders - disruption of the internal body clock that regulates the sleep-wake cycle.
5. Parasomnias - abnormal behaviors during sleep such as sleepwalking or night terrors.
6. Sleep-related movement disorders - repetitive movements during sleep such as restless legs syndrome.
7. Isolated symptoms and normal variants - brief and occasional symptoms that do not warrant a specific diagnosis.
Sleep disorders can have significant impacts on an individual's quality of life, productivity, and overall health. If you suspect that you may have a sleep disorder, it is recommended to consult with a healthcare professional or a sleep specialist for proper evaluation and treatment.
Fibromyalgia is a chronic disorder characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive difficulties. The pain typically occurs in specific tender points or trigger points, which are located on the neck, shoulders, back, hips, arms, and legs. These points are painful when pressure is applied.
The exact cause of fibromyalgia is unknown, but it appears to be related to abnormalities in the way the brain processes pain signals. It may also be associated with certain genetic factors, physical trauma, infection, or emotional stress. Fibromyalgia is more common in women than men and tends to develop between the ages of 20 and 50.
Fibromyalgia can be difficult to diagnose because its symptoms are similar to those of other conditions, such as rheumatoid arthritis, lupus, and chronic fatigue syndrome. However, a diagnosis of fibromyalgia may be made if a person has widespread pain for at least three months and tenderness in at least 11 of 18 specific points on the body when pressure is applied.
There is no cure for fibromyalgia, but medications, therapy, and lifestyle changes can help manage its symptoms. Treatment may include pain relievers, antidepressants, anti-seizure drugs, physical therapy, counseling, stress reduction techniques, and regular exercise.
Electromyography (EMG) is a medical diagnostic procedure that measures the electrical activity of skeletal muscles during contraction and at rest. It involves inserting a thin needle electrode into the muscle to record the electrical signals generated by the muscle fibers. These signals are then displayed on an oscilloscope and may be heard through a speaker.
EMG can help diagnose various neuromuscular disorders, such as muscle weakness, numbness, or pain, and can distinguish between muscle and nerve disorders. It is often used in conjunction with other diagnostic tests, such as nerve conduction studies, to provide a comprehensive evaluation of the nervous system.
EMG is typically performed by a neurologist or a physiatrist, and the procedure may cause some discomfort or pain, although this is usually minimal. The results of an EMG can help guide treatment decisions and monitor the progression of neuromuscular conditions over time.
Asthenopia is a medical term that refers to eye fatigue or discomfort, often accompanied by headache and blurred vision. It is typically caused by prolonged visual tasks such as reading, writing, or using a computer, especially in conditions of poor lighting or when focusing on a single object for a long time. Other factors that can contribute to asthenopia include uncorrected vision problems, eye strain, and dry eyes. Resting the eyes and addressing any underlying vision issues can help alleviate symptoms of asthenopia.
Depression is a mood disorder that is characterized by persistent feelings of sadness, hopelessness, and loss of interest in activities. It can also cause significant changes in sleep, appetite, energy level, concentration, and behavior. Depression can interfere with daily life and normal functioning, and it can increase the risk of suicide and other mental health disorders. The exact cause of depression is not known, but it is believed to be related to a combination of genetic, biological, environmental, and psychological factors. There are several types of depression, including major depressive disorder, persistent depressive disorder, postpartum depression, and seasonal affective disorder. Treatment for depression typically involves a combination of medication and psychotherapy.
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. It is a complex phenomenon that can result from various stimuli, such as thermal, mechanical, or chemical irritation, and it can be acute or chronic. The perception of pain involves the activation of specialized nerve cells called nociceptors, which transmit signals to the brain via the spinal cord. These signals are then processed in different regions of the brain, leading to the conscious experience of pain. It's important to note that pain is a highly individual and subjective experience, and its perception can vary widely among individuals.
Neoplasms are abnormal growths of cells or tissues in the body that serve no physiological function. They can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow growing and do not spread to other parts of the body, while malignant neoplasms are aggressive, invasive, and can metastasize to distant sites.
Neoplasms occur when there is a dysregulation in the normal process of cell division and differentiation, leading to uncontrolled growth and accumulation of cells. This can result from genetic mutations or other factors such as viral infections, environmental exposures, or hormonal imbalances.
Neoplasms can develop in any organ or tissue of the body and can cause various symptoms depending on their size, location, and type. Treatment options for neoplasms include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, among others.
"Torque" is not a term that has a specific medical definition. It is a physical concept used in the fields of physics and engineering, referring to a twisting force that causes rotation around an axis. However, in certain medical contexts, such as in discussions of spinal or joint biomechanics, the term "torque" may be used to describe a rotational force applied to a body part. But generally speaking, "torque" is not a term commonly used in medical terminology.
Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.
Exercise is defined in the medical context as a physical activity that is planned, structured, and repetitive, with the primary aim of improving or maintaining one or more components of physical fitness. Components of physical fitness include cardiorespiratory endurance, muscular strength, muscular endurance, flexibility, and body composition. Exercise can be classified based on its intensity (light, moderate, or vigorous), duration (length of time), and frequency (number of times per week). Common types of exercise include aerobic exercises, such as walking, jogging, cycling, and swimming; resistance exercises, such as weightlifting; flexibility exercises, such as stretching; and balance exercises. Exercise has numerous health benefits, including reducing the risk of chronic diseases, improving mental health, and enhancing overall quality of life.
In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.
For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.
Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.
Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.
A diaphragm is a thin, dome-shaped muscle that separates the chest cavity from the abdominal cavity. It plays a vital role in the process of breathing as it contracts and flattens to draw air into the lungs (inhalation) and relaxes and returns to its domed shape to expel air out of the lungs (exhalation).
In addition, a diaphragm is also a type of barrier method of birth control. It is a flexible dome-shaped device made of silicone that fits over the cervix inside the vagina. When used correctly and consistently, it prevents sperm from entering the uterus and fertilizing an egg, thereby preventing pregnancy.
Muscle strength, in a medical context, refers to the amount of force a muscle or group of muscles can produce during contraction. It is the maximum amount of force that a muscle can generate through its full range of motion and is often measured in units of force such as pounds or newtons. Muscle strength is an important component of physical function and mobility, and it can be assessed through various tests, including manual muscle testing, dynamometry, and isokinetic testing. Factors that can affect muscle strength include age, sex, body composition, injury, disease, and physical activity level.
Physical exertion is defined as the act of applying energy to physically demandable activities or tasks, which results in various body systems working together to produce movement and maintain homeostasis. It often leads to an increase in heart rate, respiratory rate, and body temperature, among other physiological responses. The level of physical exertion can vary based on the intensity, duration, and frequency of the activity.
It's important to note that engaging in regular physical exertion has numerous health benefits, such as improving cardiovascular fitness, strengthening muscles and bones, reducing stress, and preventing chronic diseases like obesity, diabetes, and heart disease. However, it is also crucial to balance physical exertion with adequate rest and recovery time to avoid overtraining or injury.
Post-poliomyelitis syndrome (PPS) is a condition that affects polio survivors years after recovery from the initial acute poliomyelitis infection. The symptoms of PPS include new onset weakness, fatigue, and pain in the muscles that were previously affected by the poliovirus. These symptoms can occur gradually or suddenly, and they may be worsened by exercise or other physical stressors.
PPS is thought to be caused by ongoing degeneration of the enlarged motor neurons that survived the initial polio infection. It is estimated that up to 50% of polio survivors may experience symptoms of PPS. While there is no cure for PPS, treatment typically focuses on managing symptoms and maintaining function through physical therapy, assistive devices, and pain management strategies.
Electric stimulation, also known as electrical nerve stimulation or neuromuscular electrical stimulation, is a therapeutic treatment that uses low-voltage electrical currents to stimulate nerves and muscles. It is often used to help manage pain, promote healing, and improve muscle strength and mobility. The electrical impulses can be delivered through electrodes placed on the skin or directly implanted into the body.
In a medical context, electric stimulation may be used for various purposes such as:
1. Pain management: Electric stimulation can help to block pain signals from reaching the brain and promote the release of endorphins, which are natural painkillers produced by the body.
2. Muscle rehabilitation: Electric stimulation can help to strengthen muscles that have become weak due to injury, illness, or surgery. It can also help to prevent muscle atrophy and improve range of motion.
3. Wound healing: Electric stimulation can promote tissue growth and help to speed up the healing process in wounds, ulcers, and other types of injuries.
4. Urinary incontinence: Electric stimulation can be used to strengthen the muscles that control urination and reduce symptoms of urinary incontinence.
5. Migraine prevention: Electric stimulation can be used as a preventive treatment for migraines by applying electrical impulses to specific nerves in the head and neck.
It is important to note that electric stimulation should only be administered under the guidance of a qualified healthcare professional, as improper use can cause harm or discomfort.
Neurasthenia is an outdated medical term that was once used to describe a condition characterized by physical and mental exhaustion, fatigue, anxiety, depression, and irritability. The diagnosis was commonly made during the late 19th and early 20th centuries. It was believed to be caused by exhaustion of the nervous system due to modern life's stresses and demands.
However, neurasthenia is not recognized as a distinct medical condition in modern psychiatry or neurology. The symptoms that were once attributed to neurasthenia are now more likely to be diagnosed as depression, anxiety disorders, chronic fatigue syndrome, or other conditions.
I'm sorry for any confusion, but "Work Schedule Tolerance" is not a recognized term in the medical field. It may be a term used in occupational health or human resources to refer to an employee's ability to adapt to different work schedules, such as night shifts, rotating shifts, or irregular hours. However, it is not a medical diagnosis or condition. If you have any concerns about your work schedule and how it affects your health, I would recommend speaking with a healthcare provider or occupational health professional.
In a medical context, "survivors" typically refers to individuals who have lived through or recovered from a serious illness, injury, or life-threatening event. This may include people who have survived cancer, heart disease, trauma, or other conditions that posed a significant risk to their health and well-being. The term is often used to describe the resilience and strength of these individuals, as well as to highlight the importance of ongoing support and care for those who have faced serious medical challenges. It's important to note that the definition may vary depending on the context in which it's used.
The Quadriceps muscle, also known as the Quadriceps Femoris, is a large muscle group located in the front of the thigh. It consists of four individual muscles - the Rectus Femoris, Vastus Lateralis, Vastus Intermedius, and Vastus Medialis. These muscles work together to extend the leg at the knee joint and flex the thigh at the hip joint. The Quadriceps muscle is crucial for activities such as walking, running, jumping, and kicking.
Sleep is a complex physiological process characterized by altered consciousness, relatively inhibited sensory activity, reduced voluntary muscle activity, and decreased interaction with the environment. It's typically associated with specific stages that can be identified through electroencephalography (EEG) patterns. These stages include rapid eye movement (REM) sleep, associated with dreaming, and non-rapid eye movement (NREM) sleep, which is further divided into three stages.
Sleep serves a variety of functions, including restoration and strengthening of the immune system, support for growth and development in children and adolescents, consolidation of memory, learning, and emotional regulation. The lack of sufficient sleep or poor quality sleep can lead to significant health problems, such as obesity, diabetes, cardiovascular disease, and even cognitive decline.
The American Academy of Sleep Medicine (AASM) defines sleep as "a period of daily recurring natural rest during which consciousness is suspended and metabolic processes are reduced." However, it's important to note that the exact mechanisms and purposes of sleep are still being researched and debated among scientists.
Multiple Sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system (CNS), which includes the brain, spinal cord, and optic nerves. In MS, the immune system mistakenly attacks the protective covering of nerve fibers, called myelin, leading to damage and scarring (sclerosis). This results in disrupted communication between the brain and the rest of the body, causing a variety of neurological symptoms that can vary widely from person to person.
The term "multiple" refers to the numerous areas of scarring that occur throughout the CNS in this condition. The progression, severity, and specific symptoms of MS are unpredictable and may include vision problems, muscle weakness, numbness or tingling, difficulty with balance and coordination, cognitive impairment, and mood changes. There is currently no cure for MS, but various treatments can help manage symptoms, modify the course of the disease, and improve quality of life for those affected.
I'm happy to help! However, I must clarify that "materials testing" is not a medical term per se. It is a term used in various fields, including engineering and materials science, to describe the process of subjecting materials to different tests to evaluate their properties and performance under various conditions.
In the context of medical devices or implants, materials testing may refer to the evaluation of the physical and mechanical properties of materials used in their construction. These tests can include assessments of strength, durability, biocompatibility, and other factors that are critical to ensuring the safety and efficacy of medical devices.
Medical device manufacturers must comply with regulatory standards for materials testing to ensure that their products meet specific requirements for performance, safety, and quality. These standards may vary depending on the type of device, its intended use, and the country or region in which it will be marketed and sold.
Stress fractures are defined as small cracks or severe bruising in bones that occur from repetitive stress or overuse. They most commonly occur in weight-bearing bones, such as the legs and feet, but can also occur in the arms, hips, and back. Stress fractures differ from regular fractures because they typically do not result from a single, traumatic event. Instead, they are caused by repeated stress on the bone that results in microscopic damage over time. Athletes, military personnel, and individuals who engage in high-impact activities or have weak bones (osteoporosis) are at increased risk of developing stress fractures. Symptoms may include pain, swelling, tenderness, and difficulty walking or bearing weight on the affected bone.
Anxiety: A feeling of worry, nervousness, or unease, typically about an imminent event or something with an uncertain outcome. In a medical context, anxiety refers to a mental health disorder characterized by feelings of excessive and persistent worry, fear, or panic that interfere with daily activities. It can also be a symptom of other medical conditions, such as heart disease, diabetes, or substance abuse disorders. Anxiety disorders include generalized anxiety disorder, panic disorder, social anxiety disorder, and phobias.
In medical terms, the knee is referred to as the largest and one of the most complex joints in the human body. It is a hinge joint that connects the thigh bone (femur) to the shin bones (tibia and fibula), enabling movements like flexion, extension, and a small amount of rotation. The knee also contains several other components such as menisci, ligaments, tendons, and bursae, which provide stability, cushioning, and protection during movement.
Pain measurement, in a medical context, refers to the quantification or evaluation of the intensity and/or unpleasantness of a patient's subjective pain experience. This is typically accomplished through the use of standardized self-report measures such as numerical rating scales (NRS), visual analog scales (VAS), or categorical scales (mild, moderate, severe). In some cases, physiological measures like heart rate, blood pressure, and facial expressions may also be used to supplement self-reported pain ratings. The goal of pain measurement is to help healthcare providers better understand the nature and severity of a patient's pain in order to develop an effective treatment plan.
Exercise therapy is a type of medical treatment that uses physical movement and exercise to improve a patient's physical functioning, mobility, and overall health. It is often used as a component of rehabilitation programs for individuals who have experienced injuries, illnesses, or surgeries that have impaired their ability to move and function normally.
Exercise therapy may involve a range of activities, including stretching, strengthening, balance training, aerobic exercise, and functional training. The specific exercises used will depend on the individual's needs, goals, and medical condition.
The benefits of exercise therapy include:
* Improved strength and flexibility
* Increased endurance and stamina
* Enhanced balance and coordination
* Reduced pain and inflammation
* Improved cardiovascular health
* Increased range of motion and joint mobility
* Better overall physical functioning and quality of life.
Exercise therapy is typically prescribed and supervised by a healthcare professional, such as a physical therapist or exercise physiologist, who has experience working with individuals with similar medical conditions. The healthcare professional will create an individualized exercise program based on the patient's needs and goals, and will provide guidance and support to ensure that the exercises are performed safely and effectively.
A chronic disease is a long-term medical condition that often progresses slowly over a period of years and requires ongoing management and care. These diseases are typically not fully curable, but symptoms can be managed to improve quality of life. Common chronic diseases include heart disease, stroke, cancer, diabetes, arthritis, and COPD (chronic obstructive pulmonary disease). They are often associated with advanced age, although they can also affect children and younger adults. Chronic diseases can have significant impacts on individuals' physical, emotional, and social well-being, as well as on healthcare systems and society at large.
Disorders of excessive somnolence (DES) are a group of medical conditions characterized by an increased tendency to fall asleep or experience excessive daytime sleepiness (EDS), despite having adequate opportunity and circumstances for sleep. These disorders are typically classified as central disorders of hypersomnolence according to the International Classification of Sleep Disorders (ICSD-3).
The most common DES is narcolepsy, a chronic neurological disorder caused by the brain's inability to regulate sleep-wake cycles normally. Other DES include idiopathic hypersomnia, Kleine-Levin syndrome, and recurrent hypersomnia. These disorders can significantly impact an individual's daily functioning, quality of life, and overall health.
Narcolepsy is further divided into two types: narcolepsy type 1 (NT1) and narcolepsy type 2 (NT2). NT1 is characterized by the presence of cataplexy, a sudden loss of muscle tone triggered by strong emotions, while NT2 does not include cataplexy. Both types of narcolepsy involve excessive daytime sleepiness, sleep paralysis, hypnagogic/hypnopompic hallucinations, and fragmented nighttime sleep.
Idiopathic hypersomnia is a DES without the presence of REM-related symptoms like cataplexy or sleep paralysis. Individuals with idiopathic hypersomnia experience excessive daytime sleepiness and prolonged nighttime sleep, often lasting 10 to 14 hours, but do not feel refreshed upon waking.
Kleine-Levin syndrome is a rare DES characterized by recurrent episodes of excessive sleepiness, often accompanied by cognitive impairment, altered perception, hyperphagia (excessive eating), and hypersexuality during the episodes. These episodes can last days to weeks and typically occur multiple times per year.
Recurrent hypersomnia is another rare DES with recurring episodes of excessive sleepiness lasting for several days, followed by a period of normal or reduced sleepiness. The episodes are not as predictable or consistent as those seen in Kleine-Levin syndrome.
Treatment for DES typically involves pharmacological interventions to manage symptoms and improve daytime alertness. Modafinil, armodafinil, and traditional stimulants like amphetamine salts are commonly used to treat excessive daytime sleepiness. Additionally, antidepressants may be prescribed to manage REM-related symptoms like cataplexy or sleep paralysis. Non-pharmacological interventions, such as scheduled napping and good sleep hygiene practices, can also help improve symptoms.
Mechanical stress, in the context of physiology and medicine, refers to any type of force that is applied to body tissues or organs, which can cause deformation or displacement of those structures. Mechanical stress can be either external, such as forces exerted on the body during physical activity or trauma, or internal, such as the pressure changes that occur within blood vessels or other hollow organs.
Mechanical stress can have a variety of effects on the body, depending on the type, duration, and magnitude of the force applied. For example, prolonged exposure to mechanical stress can lead to tissue damage, inflammation, and chronic pain. Additionally, abnormal or excessive mechanical stress can contribute to the development of various musculoskeletal disorders, such as tendinitis, osteoarthritis, and herniated discs.
In order to mitigate the negative effects of mechanical stress, the body has a number of adaptive responses that help to distribute forces more evenly across tissues and maintain structural integrity. These responses include changes in muscle tone, joint positioning, and connective tissue stiffness, as well as the remodeling of bone and other tissues over time. However, when these adaptive mechanisms are overwhelmed or impaired, mechanical stress can become a significant factor in the development of various pathological conditions.
Activities of Daily Living (ADL) are routine self-care activities that individuals usually do every day without assistance. These activities are widely used as a measure to determine the functional status and independence of a person, particularly in the elderly or those with disabilities or chronic illnesses. The basic ADLs include:
1. Personal hygiene: Bathing, washing hands and face, brushing teeth, grooming, and using the toilet.
2. Dressing: Selecting appropriate clothes and dressing oneself.
3. Eating: Preparing and consuming food, either independently or with assistive devices.
4. Mobility: Moving in and out of bed, chairs, or wheelchairs, walking independently or using mobility aids.
5. Transferring: Moving from one place to another, such as getting in and out of a car, bath, or bed.
There are also more complex Instrumental Activities of Daily Living (IADLs) that assess an individual's ability to manage their own life and live independently. These include managing finances, shopping for groceries, using the telephone, taking medications as prescribed, preparing meals, and housekeeping tasks.
Exercise tolerance is a term used to describe the ability of an individual to perform physical activity or exercise without experiencing symptoms such as shortness of breath, chest pain, or undue fatigue. It is often used as a measure of cardiovascular fitness and can be assessed through various tests, such as a stress test or a six-minute walk test. Exercise intolerance may indicate the presence of underlying medical conditions, such as heart disease, lung disease, or deconditioning.
Biomechanics is the application of mechanical laws to living structures and systems, particularly in the field of medicine and healthcare. A biomechanical phenomenon refers to a observable event or occurrence that involves the interaction of biological tissues or systems with mechanical forces. These phenomena can be studied at various levels, from the molecular and cellular level to the tissue, organ, and whole-body level.
Examples of biomechanical phenomena include:
1. The way that bones and muscles work together to produce movement (known as joint kinematics).
2. The mechanical behavior of biological tissues such as bone, cartilage, tendons, and ligaments under various loads and stresses.
3. The response of cells and tissues to mechanical stimuli, such as the way that bone tissue adapts to changes in loading conditions (known as Wolff's law).
4. The biomechanics of injury and disease processes, such as the mechanisms of joint injury or the development of osteoarthritis.
5. The use of mechanical devices and interventions to treat medical conditions, such as orthopedic implants or assistive devices for mobility impairments.
Understanding biomechanical phenomena is essential for developing effective treatments and prevention strategies for a wide range of medical conditions, from musculoskeletal injuries to neurological disorders.
Analysis of Variance (ANOVA) is a statistical technique used to compare the means of two or more groups and determine whether there are any significant differences between them. It is a way to analyze the variance in a dataset to determine whether the variability between groups is greater than the variability within groups, which can indicate that the groups are significantly different from one another.
ANOVA is based on the concept of partitioning the total variance in a dataset into two components: variance due to differences between group means (also known as "between-group variance") and variance due to differences within each group (also known as "within-group variance"). By comparing these two sources of variance, ANOVA can help researchers determine whether any observed differences between groups are statistically significant, or whether they could have occurred by chance.
ANOVA is a widely used technique in many areas of research, including biology, psychology, engineering, and business. It is often used to compare the means of two or more experimental groups, such as a treatment group and a control group, to determine whether the treatment had a significant effect. ANOVA can also be used to compare the means of different populations or subgroups within a population, to identify any differences that may exist between them.
Fatigue
Synaptic fatigue
Static fatigue
Voter fatigue
Compassion fatigue
Alarm fatigue
Pandemic fatigue
Chronic fatigue
Museum fatigue
Fatigue Mountain
Donor fatigue
Fatigue testing
Vibration fatigue
Zoom fatigue
Olfactory fatigue
Fatigue limit
Condom fatigue
Pilot fatigue
Corrosion fatigue
Media fatigue
Battle fatigue
Metal Fatigue
Zero Fatigue
Decision fatigue
Fatigue duty
Auditory fatigue
Password fatigue
Muscle fatigue
Change fatigue
Fatigue (disambiguation)
Listener fatigue
Fatigue (material)
Adrenal fatigue
AIDS fatigue
Exhaustion5
- Fatigue describes a state of tiredness (which is not sleepiness) or exhaustion. (wikipedia.org)
- But exhaustion that disrupts your daily life and doesn't get better after a good night's sleep has its own medical term: fatigue. (arthritis.org)
- Fatigue is a feeling of tiredness or exhaustion. (macmillan.org.uk)
- Fatigue can cause physical, emotional, and mental exhaustion. (oncolink.org)
- Readers are also invited to participate in a research study aimed at developing a Zoom Exhaustion & Fatigue Scale (ZEF) Scale. (stanford.edu)
Symptoms23
- Below, we'll discuss what ad fatigue is, common symptoms attributed to ad fatigue, and what you can do to fix it. (hubspot.com)
- Drowsiness and apathy (a feeling of not caring about what happens) can be symptoms that go along with fatigue. (nih.gov)
- Chronic fatigue syndrome (CFS) is a condition in which symptoms of fatigue persist for at least 6 months and do not resolve with rest. (nih.gov)
- It is diagnosed based on the presence of a specific group of symptoms and after all other possible causes of fatigue are ruled out. (nih.gov)
- Several studies reveal high correlations of tumor-specific treatment and fatigue symptoms, or emphasize that fatigue is commonly increased during treatment and decreases after the end of treatment. (medscape.com)
- Among cancer-related symptoms, cancer-related fatigue(CRF) shows the highest prevalence rates over the whole trajectory of cancer. (medscape.com)
- Temporarily relieves symptoms of stress, fatigue, and simple nervous tension. (nih.gov)
- Nicolson GL, Gan R, Haier J. Multiple co-infections (Mycoplasma, Chlamydia, human herpes virus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms. (medscape.com)
- Read about the causes of fatigue (like illness and certain medications), and learn about chronic fatigue syndrome and its symptoms. (nih.gov)
- Chronic Fatigue Syndrome, or CFS, comprises a complex of symptoms characterized by chronic, debilitating fatigue and other nonspecific symptoms. (cdc.gov)
- RESEARCH OBJECTIVES Background Chronic fatigue syndrome (CFS) is a multisystem syndrome characterized by months of debilitating fatigue frequently associated with myalgia, headache, sore throat, low grade fever, cognitive complaints, gastrointestinal symptoms, and tender lymph nodes. (nih.gov)
- Gastroesophageal reflux disease, known as GERD, can cause fatigue in people who have difficulty sleeping due to symptoms. (medicalnewstoday.com)
- If a person has the symptoms above and believes that they are experiencing fatigue, they may have GERD and should make an appointment with a doctor. (medicalnewstoday.com)
- Heightened symptoms can prevent a person from sleeping properly and may eventually lead to fatigue. (medicalnewstoday.com)
- Anyone experiencing fatigue should make a note of other symptoms. (medicalnewstoday.com)
- To diagnose GERD fatigue, a doctor will begin by going through a person's medical history and asking about their symptoms. (medicalnewstoday.com)
- Headaches, nausea, and fatigue are very common symptoms of other health conditions. (medicalnewstoday.com)
- Understanding of the historical developments in the field of care giving that gave rise to the concept of compassion fatigueAbility to articulate the etiology of compassion fatigue through its two primary components: secondary traumatic stress and burnout.Clear understanding of the potential symptoms and effects associated with compassion fatigue. (scoop.it)
- Fatigue is one of the symptoms most often reported by people with COVID-19, and their tiredness can linger. (nih.gov)
- Chronic fatigue syndrome, also known as chronic fatigue and immune dysfunction syndrome (CFIDS) or myalgic encephalomyelitis (ME), is a complex illness marked by a wide variety of symptoms. (nolo.com)
- It's important to look at what other symptoms you may be experiencing, in addition to constipation and fatigue. (healthline.com)
- If you feel that your constipation and fatigue are the result of an underlying condition, speak with your doctor about how to best manage these symptoms and determine the cause. (healthline.com)
- Chronic Fatigue Syndrome (CFS) is the internationally accepted term for long-term, disabling fatigue along with other symptoms such as musculoskeletal pain, sleep disturbances and impaired concentration, which has no known medical cause. (scirp.org)
Myalgic8
- Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, long-term illness that affects many body systems. (cdc.gov)
- Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An IOM Report on Redefining an Illness. (medscape.com)
- Chronic fatigue syndrome, also known as myalgic encephalomyelitis, post-viral fatigue syndrome and various other names, is a syndrome of unknown and possibly multiple etiology, affecting the central nervous system, immune, and many other systems and organs. (sciencedaily.com)
- Another name for it is myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (nih.gov)
- no cure or approved treatment for myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS). (nih.gov)
- have not yet identified what causes myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS). (nih.gov)
- Childhood predictors of self-reported chronic fatigue syndrome/myalgic encephalomyelitis in adults: national birth cohort study BMJ Online First. (news-medical.net)
- One cause of debilitating fatigue is a serious disease called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (nih.gov)
20221
- Aug. 31, 2022 Since the beginning of the pandemic, SARS-CoV-2 has been suspected of causing chronic fatigue syndrome (ME/CFS). (sciencedaily.com)
Causes of fatigue4
- Although there has been a lot of research within the last decade, there is only limited evidence for a comprehensive theory explaining the causes of fatigue. (medscape.com)
- Not getting adequate and healthy food and fluids can be causes of fatigue that fly under the radar. (arthritis.org)
- Add this to the many other causes of fatigue that existed before the pandemic-such as lack of sleep, mental health concerns, and health conditions like anemia A condition caused by low levels of red blood cells or hemoglobin in the blood. (nih.gov)
- But not much is known about other causes of fatigue. (nih.gov)
Cancer-related fatigue9
- Cancer-related fatigue does not only affect the individual patient and his or her spouse, but also has a lot of consequences on the health economy. (medscape.com)
- Cite this: Cancer-related Fatigue - Medscape - Aug 01, 2011. (medscape.com)
- Oct. 3, 2023 Cancer-related fatigue is a debilitating yet all-too-common condition, which can severely affect quality of life for patients undergoing treatment. (sciencedaily.com)
- As many as 9 out of 10 people with cancer (90%) get cancer-related fatigue (CRF). (macmillan.org.uk)
- Cancer-related fatigue usually gets better after treatment finishes. (macmillan.org.uk)
- The cause of cancer-related fatigue (CRF) is not fully understood. (macmillan.org.uk)
- Cancer-related fatigue may also make tiredness caused by other conditions worse. (macmillan.org.uk)
- If you are older you are more likely to be affected by cancer-related fatigue. (macmillan.org.uk)
- What causes cancer-related fatigue and how is it treated? (oncolink.org)
20201
- The exhibition I originally made Decision Fatigue for opened in late February 2020 and closed during the first NYC lockdown. (e-flux.com)
Possible Causes1
- Because it has so many possible causes, it can be hard for doctors to diagnose the origins of someone's fatigue. (nih.gov)
Depression10
- If you have long-term (chronic) pain or depression, treating it often helps the fatigue. (nih.gov)
- [ 27-29 ] As fatigue is a common symptom of depression and is often associated with anxiety, diagnostic efforts that reliably differentiate CRF from depression are required. (medscape.com)
- Nevertheless the interaction between fatigue and depression or anxiety is not yet completely understood. (medscape.com)
- Is it fatigue or depression? (cancer.org)
- Some signs of fatigue or weakness often look a lot like those of depression , and it's easy to confuse the two. (cancer.org)
- You can have fatigue and not be depressed, although some people have both fatigue and depression. (cancer.org)
- In fact, according to a 2017 study published in Current Rheumatology Reports, your fatigue level probably has more to do with other contributing factors, including obesity, physical inactivity, sleep disturbance and depression. (arthritis.org)
- A 2017 study suggested that migraines and fatigue, as a symptom of depression, may be linked by a dysfunction of the hypothalamus. (medicalnewstoday.com)
- Conditions such as anxiety, depression and stress can make fatigue worse. (macmillan.org.uk)
- There is only one answer, which will prove to be a sure-fire success in alleviating fatigue driven depression and negative, gloomy thoughts. (positivehealth.com)
Centers1
- On March 20-23, 2017, thirteen participants from the National Institute for Occupational Safety and Health (NIOSH) and the Centers for Disease Control and Prevention (CDC) attended the 10th International Conference on Managing Fatigue, in San Diego, California. (cdc.gov)
Managing Fatigue1
- In considering other lifestyle behaviors, there is limited literature on effects of diet, energy balance, and/or nutrient density in SLE patients, but diet intervention has been favorably associated with managing fatigue in other disorders (e.g., cardiovascular disease and age-related functional decline). (nih.gov)
Tiredness4
- Fatigue is a feeling of weariness, tiredness, or lack of energy. (nih.gov)
- Fatigue (in the general usage sense of normal tiredness) can include both physical and mental fatigue. (wikipedia.org)
- Fatigue is often described as an uncomfortable tiredness, whereas sleepiness can be comfortable and inviting. (wikipedia.org)
- As the name suggests, chronic fatigue syndrome is characterized by persistent tiredness that cannot be relieved with rest. (nolo.com)
Etiology1
- There is no agreement on the etiology of chronic fatigue syndrome (CFS), and the main theories (behavioural and viral/immune) do not satisfactorily explain the condition. (scirp.org)
Lack5
- Fatigue is a lack of energy and motivation. (nih.gov)
- Fatigue can be a normal and important response to physical activity, emotional stress, boredom, or lack of sleep. (nih.gov)
- Physical fatigue can be caused by a lack of energy in the muscle, by a decrease of the efficiency of the neuromuscular junction or by a reduction of the drive originating from the central nervous system, and can be reversed by rest. (wikipedia.org)
- Lack of exercise, using extra energy to move more bodyweight and metabolic changes that often accompany obesity also contribute to fatigue. (arthritis.org)
- That lack of empathy, whether it's a result of compassion fatigue, crippling climate anxiety, or just being kind of a jerk, is bad enough when it's coming from your fellow Americans. (salon.com)
Headaches6
- Headaches, nausea, and fatigue can sometimes occur together. (medicalnewstoday.com)
- However, there are several conditions that can cause headaches, nausea, and fatigue that may require medical attention. (medicalnewstoday.com)
- However, it is not clear whether headaches cause fatigue or vice versa. (medicalnewstoday.com)
- Mayo Clinic researchers have discovered an effective new way to treat giant cell arteritis (GCA), a debilitating cause of headaches, fatigue, muscle pain and even blindness. (news-medical.net)
- It can cause fatigue, dizziness, and headaches. (nih.gov)
- Sufferers report extreme fatigue, joint pain, headaches and memory problems, but doctors still do not know the cause or how to cure it. (telegraph.co.uk)
Disturbance1
- But studies show that obese people with no sleep disturbance are also fatigued. (arthritis.org)
Experience debilit1
- Approximately half of hemodialysis patients experience debilitating fatigue following their treatment. (nih.gov)
Anxiety1
- Let employees know (or let your team members know) that there are still issues causing Zoom fatigue that may be showing up as Zoom Anxiety. (entrepreneur.com)
XMRV4
- Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome. (medscape.com)
- Absence of XMRV retrovirus and other murine leukemia virus-related viruses in patients with chronic fatigue syndrome. (medscape.com)
- The discovery of XMRV in 2 major diseases, prostate cancer and now chronic fatigue syndrome, is very exciting," says Dr. Robert H. Silverman, a co-author at the Cleveland Clinic. (nih.gov)
- XMRV and chronic fatigue syndrome: Why? (scienceblogs.com)
Worsen3
- Be aware that some antidepressant medicines may cause or worsen fatigue. (nih.gov)
- Sedatives also tend to worsen fatigue. (nih.gov)
- Being fatigued, in turn, can worsen pain and make it more difficult to manage. (arthritis.org)
Sleeping disorders1
- There is also a strong correlation of fatigue with sleeping disorders, which may represent a potential secondary cause of fatigue. (medscape.com)
Occurs5
- These are both examples of ad fatigue - an issue that occurs when users become too accustomed to a specific type of ad, thus reducing its effectiveness. (hubspot.com)
- Ad fatigue occurs when your audience sees your ads so often that they become bored with them and stop paying attention. (hubspot.com)
- When fatigue occurs independently of physical or mental exertion, or does not resolve after rest or sleep, it may have other causes, such as a medical condition. (wikipedia.org)
- Also, fibromyalgia sometimes occurs alongside GERD, and one symptom is fatigue. (medicalnewstoday.com)
- The NTSB investigation report found that Atina's master was, at the time of the incident, having to deal with critical manoeuvres while deeply affected by acute fatigue - which occurs when a person has had less than four hours of sleep over a 24-hour period. (imarest.org)
Chronic Pain2
- Fatigue is associated with a wide variety of conditions including autoimmune disease, organ failure, chronic pain conditions, mood disorders, heart disease, infectious diseases and post-infectious disease states. (wikipedia.org)
- Medicinal cannabis boosts the health and quality of life of patients suffering from mental health conditions, chronic pain and fatigue, an Australian study shows. (yahoo.com)
Diagnose2
- No lab tests or x-rays can diagnose or show your level of fatigue. (cancer.org)
- Chronic fatigue syndrome (CFS) is a complicated disease for doctors to diagnose - and even fully understand. (nih.gov)
Decrease fatigue3
- Many people still suggest rest as a way to decrease fatigue. (oncolink.org)
- The way to decrease fatigue is not by flying more hours in a day," Sullenberger said. (foxnews.com)
- Moreover, he provides suggestions for consumers and organizations on how to leverage the current features on videoconferences to decrease fatigue. (stanford.edu)
Decreases2
- While excess mortality has decreased in SLE patients since the 1970s, a major ongoing cause of morbidity in this population is chronic, debilitating fatigue that significantly decreases quality of life, and increases risk of work disability and associated health care costs. (nih.gov)
- But some people with severe inflammatory arthritis have a condition called cachexia, in which muscle mass decreases and fatigue increases. (arthritis.org)
2017 study1
- A 2017 study published in Scandinavian Journal of Medicine & Science in Sports found that people with fibromyalgia who spent less time sitting and more time doing light physical activity had lower levels of fatigue and pain than those who were inactive. (arthritis.org)
Relieve fatigue3
- Your healthcare team may be able to help prevent or relieve fatigue and improve your quality of life. (macmillan.org.uk)
- Complementary therapies such as massage, relaxation techniques, meditation, and yoga have been shown to help relieve fatigue. (oncolink.org)
- If you are having pain, proper pain management can also help relieve fatigue. (oncolink.org)
Compassion fatigue3
- Certified Compassion Fatigue Professional (CCFP. (scoop.it)
- Hurricane season is just getting started, and some U.S. politicians (cough cough TRUMP cough cough) already seem to be suffering from climate-related compassion fatigue. (salon.com)
- Compassion fatigue is a phenomenon wherein people withdraw after long periods of taking on others' emotional burdens. (salon.com)
Diagnosis4
- [ 17 ] There is also some evidence that the level of fatigue among cancer patients, as well as in long-term survivors several years after diagnosis, is higher than among the normal population. (medscape.com)
- The Office of Research on Women's Health (ORWH) and cosponsoring Institutes and Offices (IC) of the National Institutes of Health (NIH) invite submission of investigator-initiated research grant applications to support research on the epidemiology, diagnosis, pathophysiology, and treatment of chronic fatigue syndrome (CFS) in diverse groups and across the life span. (nih.gov)
- In cases involving chronic fatigue syndrome, Social Security regulations require that objective medical signs and laboratory findings support the existence of the diagnosis. (nolo.com)
- The differential diagnosis of fatigue includes lifestyle issues, physical conditions, mental disorders, and treatment side effects. (nih.gov)
Syndrome19
- One disorder that causes extreme fatigue is chronic fatigue syndrome (CFS). (medlineplus.gov)
- Cytokine signature associated with disease severity in chronic fatigue syndrome patients. (medscape.com)
- Chronic fatigue syndrome in the emergency department. (medscape.com)
- Sapra A, Bhandari P. Chronic Fatigue Syndrome. (medscape.com)
- Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors. (medscape.com)
- Analysis of cerebrospinal fluid from chronic fatigue syndrome patients for multiple human ubiquitous viruses and xenotropic murine leukemia-related virus. (medscape.com)
- No association of chronic Chlamydia pneumoniae infection with chronic fatigue syndrome. (medscape.com)
- Profound and debilitating fatigue is the most common complaint reported among individuals with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 diabetes, celiac disease, chronic fatigue syndrome, and rheumatoid arthritis. (wikipedia.org)
- This program announcement, Chronic Fatigue Syndrome Pathophysiology, is related to the priority area of chronic disabling diseases. (nih.gov)
- o dysfunctions in the baroreceptor, ventricular mechanoreceptor, and other cardiovascular reflex pathways in the chronic fatigue syndrome and in acute and chronic episodes of hypotension and syncope observed in CFS patients. (nih.gov)
- The above text is excerpted from the Wikipedia article " Chronic fatigue syndrome ", which has been released under the GNU Free Documentation License . (sciencedaily.com)
- Scientists have detected the DNA of a retrovirus in the blood of patients with chronic fatigue syndrome. (nih.gov)
- The discovery raises the possibility that the virus may be a contributing factor in chronic fatigue syndrome. (nih.gov)
- Chronic fatigue syndrome, or CFS, is a debilitating disease that affects millions of people in the United States. (nih.gov)
- A status report on chronic fatigue syndrome. (nih.gov)
- What is chronic fatigue syndrome (CFS)? (nih.gov)
- Chronic fatigue syndrome (CFS) is a complex condition that may stop people from taking part in their usual activities. (medicalnewstoday.com)
- The Social Security Administration (SSA) is generally skeptical of disability claims based solely on chronic fatigue syndrome (CFS). (nolo.com)
- Social Security does not have a Blue Book listing for chronic fatigue syndrome, a fact that shouldn't surprise the many sufferers of CFS used to dealing with suspicion about their disease. (nolo.com)
Weakness3
- Feeling weakness or fatigue is common in people with cancer, but it's different for each person. (cancer.org)
- I complete my 6 cycles of Carbo/Taxol on 15 May '02 and have been experiencing alot of body aches, weakness and this overwhelming fatigue. (cancer.org)
- While having my treatments I did have weakness and fatigue that would occur the day after my treatment, but it improved by the time I had my next go-round, (21 days). (cancer.org)
Patients6
- KUH desires to bring stakeholders (patients, researchers, clinicians, CMS, and FDA) together through a workshop on post-dialysis fatigue to summarize the state of the science and clinical care. (nih.gov)
- An urgent, unmet need in the management of patients with SLE is identification of effective strategies to reduce fatigue. (nih.gov)
- Preliminary data from lupus patients showed that regular aerobic exercise can improve quality of life and reduce fatigue. (nih.gov)
- Results from the first three months of the treatment showed improvements in the patients' health-related quality of life and fatigue across all assessed conditions, except sleep disorders. (yahoo.com)
- The QUEST results show that medicinal cannabis provides statistically, and more importantly, clinically significant improvements in pain levels, fatigue and quality of life for patients,' he said in a statement. (yahoo.com)
- Patients with chronic fatigue may respond to cognitive behavior therapy. (nih.gov)
Occur1
- Constipation and fatigue frequently occur together. (healthline.com)
Treatments6
- Medical problems, treatments, and personal habits can add to fatigue. (medlineplus.gov)
- Stimulants (including caffeine) are not effective treatments for fatigue. (nih.gov)
- I've been on pain pills since starting my treatments and have found that they actually help in the fatigue. (cancer.org)
- In this article, learn about the causes of a headache , nausea, and fatigue, as well as about the possible treatments. (medicalnewstoday.com)
- We do not know exactly why cancer treatments cause fatigue. (macmillan.org.uk)
- These treatments can also make you feel fatigued. (healthline.com)
Affects2
- Ask your doctor or nurse how to describe your fatigue so they can understand how it affects your everyday life. (cancer.org)
- Fatigue significantly affects the quality of life for people with many forms of arthritis-related diseases, including rheumatoid arthritis , psoriatic arthritis , spondyloarthritis , lupus , fibromyalgia and osteoarthritis . (arthritis.org)
Dehydration2
- If you love junk food and don't drink enough water or other healthy beverages, your fatigue could be from dehydration and vitamin deficiency. (arthritis.org)
- Dehydration and nutritional issues may cause constipation and fatigue. (healthline.com)
Muscles4
- Physical fatigue, or muscle fatigue, is the temporary physical inability of muscles to perform optimally. (wikipedia.org)
- Without enough red blood cells, your muscles get tired fast, resulting in fatigue. (arthritis.org)
- Being too inactive may make your muscles become weaker (deconditioning) and make fatigue worse. (macmillan.org.uk)
- This oxygen is the fuel for muscles, and low levels of it can lead to fatigue. (oncolink.org)
Make4
- If you're noticing reduced social engagement, it could be a sign that you've inflicted ad fatigue onto your followers in ways that make them less motivated to interact with all your content: both paid and organic. (hubspot.com)
- Allow yourself to rest, but do not overdo it as too much rest can make fatigue worse. (oncolink.org)
- Not eating a balanced diet can make fatigue worse. (oncolink.org)
- However, there are things pilots can do to combat that fatigue and make sure they're fit to be in the cockpit. (foxnews.com)
Healthcare1
- Healthcare providers do not know exactly what causes fatigue. (oncolink.org)
Common2
- Fatigue is a common symptom, and it is usually not due to a serious disease. (nih.gov)
- Fatigue is one of the most common side effects of cancer treatment. (oncolink.org)
Research6
- Research also suggests that mental fatigue is closely linked to the concept of ego depletion, though the validity of the concept is disputed. (wikipedia.org)
- Despite this, according to recent research conducted by Stanford University, the primary cause of the condition of Zoom fatigue is the endless staring contest with yourself. (entrepreneur.com)
- It's generally agreed that the sensation of fatigue can involve difficulty in starting or continuing an activity," says Dr. Vicky Whittemore, who is involved in NIH's fatigue-related research programs. (nih.gov)
- I think this research will help us better understand fatigue and get at the underlying mechanisms. (nih.gov)
- I call it 'upgrade fatigue,'" says John Feland, CEO of Argus Insights, the research firm that put together the report. (cio.com)
- This research mainly discusses the phenomenon of visual fatigue in visual communication design integrated with artificial intelligence. (hindawi.com)
Thyroid1
- Other health conditions like diabetes , heart problems or low thyroid function can also cause fatigue. (macmillan.org.uk)
People5
- People with ME/CFS have severe fatigue and sleep problems. (cdc.gov)
- People with cancer describe fatigue in many ways. (cancer.org)
- Fatigue and sleep problems go hand-in-hand for many people with arthritis. (arthritis.org)
- A review of published medical literature shows that functional endoscopic sinus surgery can help people suffering from chronic fatigue caused by sinusitis. (news-medical.net)
- Preferred by 95% of people over standard anti fatigue mats*, employees feel more comfortable - making them ready ™ to be productive. (cintas.com)
Muscle fatigue3
- Physical fatigue results from muscle fatigue brought about by intense physical activity. (wikipedia.org)
- The onset of muscle fatigue during physical activity is gradual, and depends upon an individual's level of physical fitness - other factors include sleep deprivation and overall health. (wikipedia.org)
- They're packed with B vitamins which help your body convert food into energy, and are rich in magnesium which helps fight muscle fatigue. (healthline.com)
Severe fatigue1
- Professor Trudie Chalder, of Kings College London said: "CFS is a chronic and debilitating condition which is characterised by severe fatigue. (telegraph.co.uk)
Quality of l2
- Fatigue can have significant negative impacts on quality of life. (wikipedia.org)
- Exercise has been shown to improve fatigue levels and quality of life. (oncolink.org)
Empathy1
- This concept of "practical empathy" was identified as a way to counter empathy fatigue in managers and frustration in employees due to poorly executed empathy initiatives. (scoop.it)
Severity1
- A randomized placebo-controlled double-blind trial to evaluate the effect of cytokine inhibition with anakinra, a recombinant human interleukin-1 (IL-1) receptor antagonist, was conducted and did not show any improvement in fatigue severity both in the short term (4 weeks) or the long term (6 months). (medscape.com)
Profound1
- It's characterized by profound fatigue that doesn't improve with bed rest and can be exacerbated or re-kindled by physical or mental activity. (nih.gov)
Reduce fatigue1
- To study the effects of intervening on these two potential modifiable lifestyle behaviors (PA and diet) this study designed the Lupus Intervention Fatigue Trial (LIFT) to compare the effectiveness of a motivational interviewing program intervention versus a patient educational program control to reduce fatigue in persons with lupus. (nih.gov)
Medical3
- Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. (wikipedia.org)
- The use of the term "fatigue" in medical contexts may carry inaccurate connotations from the general usage of the word. (wikipedia.org)
- Fatigue can be classified as secondary to other medical conditions, physiologic, or chronic. (nih.gov)
Anemia1
- Fatigue in arthritis may be caused by anemia - a shortage of red blood cells. (arthritis.org)