Rare indolent tumors comprised of neoplastic glial and neuronal cells which occur primarily in children and young adults. Benign lesions tend to be associated with long survival unless the tumor degenerates into a histologically malignant form. They tend to occur in the optic nerve and white matter of the brain and spinal cord.
Loss of structural differentiation and useful function of neoplastic cells.
A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and BRAIN STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation.
Primary or metastatic neoplasms of the CEREBELLUM. Tumors in this location frequently present with ATAXIA or signs of INTRACRANIAL HYPERTENSION due to obstruction of the fourth ventricle. Common primary cerebellar tumors include fibrillary ASTROCYTOMA and cerebellar HEMANGIOBLASTOMA. The cerebellum is a relatively common site for tumor metastases from the lung, breast, and other distant organs. (From Okazaki & Scheithauer, Atlas of Neuropathology, 1988, p86 and p141)
Studies beyond the bachelor's degree at an institution having graduate programs for the purpose of preparing for entrance into a specific field, and obtaining a higher degree.
The teaching staff and members of the administrative staff having academic rank in an educational institution.
Individuals enrolled in a school or formal educational program.
Educational programs for pharmacists who have a bachelor's degree or a Doctor of Pharmacy degree entering a specific field of pharmacy. They may lead to an advanced degree.
The teaching staff and members of the administrative staff having academic rank in a medical school.
Auditory and visual instructional materials.
The educational process of instructing.

Ictus expectoratus: a sign of complex partial seizures usually of non-dominant temporal lobe origin. (1/68)

Spitting (or expectoration) is rarely seen with seizures. In Western society, spitting is a striking behavioral aberration. A 13-year-old child had intermittent agitated behavior, episodes of rage, spitting and confusion lasting up to 2 minutes. He stood up in church and told the preacher to 'shut up and sit down'. Epilepsy monitoring revealed spitting with polysharp and spike seizures resolved over the right temporal lobe. Magnetic resonance imaging revealed a right temporal lobe ganglioglioma. Spitting seizures resolved after resection. Ictal expectoration is rare. It may occur with epigastric aura, nausea, chewing, swallowing and fumbling. Literature review disclosed 17 cases, 12 of which arose from the non-dominant hemisphere. Most regressed with surgery and anticonvulsants.  (+info)

Ganglioglioma of the optic chiasm: case report and review of the literature. (2/68)

We report a case of a hypothalamic chiasmatic ganglioglioma in a 21-year-old woman who presented with hyperprolactinemia and developed visual field defects. This circumscribed cystic lesion with an enhancing mural nodule was radiologically indistinguishable from a pilocytic astrocytoma. Although rare, gangliogliomas should be included in the differential diagnosis of lesions occurring in this area of the brain.  (+info)

Mixed conventional and desmoplastic infantile ganglioglioma: an autopsied case with 6-year follow-up. (3/68)

We describe a case of desmoplastic infantile ganglioglioma (DIG) arising in the ventral diencephalon of a 3-1/2-month-old boy. On biopsy, the tumor featured a desmoplastic, S-100 protein and GFAP immunoreactive stromal element, as well as a variable spectrum of ganglion cells. Electron microscopy demonstrated astrocytes, and morphologically fibroblasts, as well as neurons containing 120-nm dense core granules. In addition, tubular structures composed of tightly apposed cells with features of astrocytes and of Schwann-like cells were also noted. Devoid of fibroblasts, the tubular structures were surrounded by a single basal lamina. At autopsy 6 years later, the multinodular, cystic mass had replaced the diencephalon, extended into both temporal lobes as well as the optic nerves, and showed marked leptomeningeal involvement. Microscopically, superficial portions of the tumor consisted of typical DIG, whereas deep, nondesmoplastic portions exhibited pattern variation ranging from pilocytic astrocytoma to ganglioglioma and gangliocytoma. There was also a minor element of small, 'primitive-appearing' neuroepithelial cells. Dysplastic ganglion cells variously reactive for neurofilament protein and synaptophysin were present throughout the tumor. Our study not only confirms DIG as a variant of ganglioglioma, one capable of slow growth, infiltration, and fatal progression but suggests that its differentiating potential includes elements of both the central and peripheral nervous systems. If so, their derivation may be from multipotential cells of the neural plate.  (+info)

Cerebellopontine angle ganglioglioma: MR findings. (4/68)

We present a case of cerebellopontine (CP) angle ganglioglioma in a young child with developmental delay and no trigeminal nerve symptoms. MR imaging demonstrated a mass of homogeneous low signal intensity in the left CP angle on T1-weighted images with no enhancement with gadolinium, and of relatively homogeneous high signal intensity on T2-weighted images.  (+info)

Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction. (5/68)

Fas (APO-1/CD95/TNFRSF6) is a member of the tumor necrosis/nerve growth factor receptor family that signals apoptotic cell death in sensitive cells. Expression of Fas and its agonistic ligand (FasL/TNFSF6) was investigated in ex vivo pediatric brain tumor specimens of various histologic types. Fas expression was identified in all of the 18 tumors analyzed by flow cytometry and immunohistochemistry. FasL expression was identified in most of the 13 tumors analyzed by both Western analysis and immunohistochemistry. Nine of these tumor specimens were treated with either the agonistic anti-Fas antibody (APO-1) in combination with protein A or FasL in short-term cytotoxicity assays. Sensitivity to apoptosis induced by the topoisomerase II inhibitor, etoposide, was also assessed. Despite the presence of Fas, all the specimens analyzed demonstrated a high degree of resistance to Fas-mediated apoptosis. These 9 specimens also showed a high degree of resistance to etoposide. Only 2 of the 9 specimens were susceptible to etoposide-induced cell death, whereas only 3 were sensitive to Fas-mediated apoptosis. One brain tumor was sensitive to both Fas ligation and etoposide treatment. This contrasted with the high degree of susceptibility to both etoposide- and Fas-induced apoptosis observed in the reference Jurkat cell line. The results suggest that Fas expression may be a general feature of tumors of the CNS and that a significant degree of resistance to Fas-mediated apoptosis may exist in ex vivo pediatric brain tumor specimens.  (+info)

Language processing during natural sleep in a 6-year-old boy, as assessed with functional MR imaging. (6/68)

Functional MR imaging for language lateralization was performed in a 6-year-old child before neurosurgical intervention. A passive story-listening task was used; this revealed a bilateral language network. The task was repeated during the same session when the child had fallen asleep and surprisingly yielded strong activation in similar language areas. Our findings suggest that language processing does occur during natural sleep, even in young children. This potentially allows for an assessment of language functions, even in sleeping children.  (+info)

Gangliogliomas: A report of five cases. (7/68)

Gangliogliomas are rare tumors of the Central Nervous System. Five gangliogliomas were diagnosed out of 1560 brain tumours surgically resected out in a period of 5 years accounting for 0. 32%. We have tried to discuss in detail the pathological features of these tumours and have mentioned the clinical and radiological features associated with them. All the slides, tissue blocks and pathology reports of the surgical specimens of gangliglioma were reviewed and the clinical and radiological data reviewed. The ages of the patients ranged from 7-65 years with 4 males and 1 female. The tumors were located in the lateral ventricle (a rare site), temporal, parietal and the frontal lobes with duration of seizures varying from 1-9 years. The tumors were diagnosed by the presence of a dual population of neoplastic ganglionic and glial components. The glial components consisted of pilocytic astrocytes (l case), fibrillary astrocytes (2 cases), oligodendrocytes (1 case) and anaplastic astrocytes and oligodendrocytes (1 case). There was one-grade I GG, three-Grade II GGs and one-grade III GG. Astrocytes were the commonest glial component of GGs, either pilocytic or fibrillary. Oligodendrocytes as the glial component of GGs was seen in 2 cases one of which was anaplastic and this is a rare finding.  (+info)

MR imaging in the diagnosis of desmoplastic infantile tumor: retrospective study of six cases. (8/68)

BACKGROUND AND PURPOSE: Desmoplastic infantile tumors (DITs) are rare supratentorial tumors of infancy with a favorable prognosis. Radiologic and histologic features of DIT are misleading, and DIT may be misinterpreted as a malignant lesion. We have studied the usefulness of MR imaging in the diagnosis of these tumors. METHODS: Between 1995 and 2002, six DITs were diagnosed in young children at our institution. Neuroimaging, age at diagnosis, sex, clinical presentation, symptoms duration, follow-up, and development were studied retrospectively. Contrast-enhanced CT and MR images were available. MR study included T1-, T2-, and postgadolinium T1-weighted sequences in the axial, sagittal, and coronal planes. RESULTS: These tumors were massive and predominantly cystic, with preferential frontal and parietal involvement. Typically, a DIT appears as a hypointense cystic mass with an isointense peripheral solid component on T1-weighted MR images. The peripheral solid component enhances after gadolinium administration. On T2-weighted MR images, the cystic component is hyperintense and the solid portion isointense or heterogeneous. The cystic portion is usually located deep inside the lesion, whereas its solid portion is peripheral. Meningeal enhancement and thickening adjacent to the solid portion of the tumor, calcifications, bone abnormalities adjacent to the tumor consisting of thinning and deformation were noted in 50% of our cases. Edema was usually absent or moderate. Median follow-up was 32 months, and no recurrence was noted except for one atypical case with incomplete excision, which led to the patient's death. CONCLUSION: Despite their malignant appearance, MR imaging features of DIT may help in the diagnosis and obviate unnecessary chemotherapy or radiation therapy.  (+info)

Ganglioglioma is a rare, typically slow-growing tumor that occurs in the brain or spinal cord. It is composed of both neuronal (ganglion cell) and glial elements. These tumors most commonly occur in the temporal lobe of the brain and are usually found in children and young adults.

Gangliogliomas can be benign or malignant, with the majority being low-grade (benign). Symptoms vary depending on the location of the tumor but may include seizures, headaches, changes in behavior or cognition, and motor weakness or paralysis. Treatment typically involves surgical removal of the tumor, and in some cases, radiation therapy or chemotherapy may be recommended.

It's important to note that while I strive to provide accurate information, my responses should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider for any medical concerns.

Anaplasia is a term used in pathology to describe the loss of differentiation and cellular organization in malignant tumors. It is characterized by the presence of large, pleomorphic cells with high mitotic activity, absence of mature tissue architecture, and lack of functional specialization. Anaplastic tumors are often aggressive and have a poor prognosis due to their rapid growth and tendency to metastasize. The term "anaplasia" is derived from the Greek words "ana," meaning "back" or "against," and "plasis," meaning "formation" or "molding."

Complex partial epilepsy, also known as temporal lobe epilepsy or focal impaired awareness epilepsy, is a type of epilepsy characterized by recurrent, unprovoked seizures that originate in the temporal lobe or other localized areas of the brain. These seizures typically involve alterations in consciousness or awareness, and may include automatisms (involuntary, repetitive movements), such as lip smacking, fidgeting, or picking at clothes. Complex partial seizures can last from a few seconds to several minutes and may be followed by a post-ictal period of confusion or fatigue.

Complex partial epilepsy is often associated with structural abnormalities in the brain, such as hippocampal sclerosis, tumors, or malformations. It can also be caused by infectious or inflammatory processes, vascular disorders, or genetic factors. The diagnosis of complex partial epilepsy typically involves a thorough neurological evaluation, including a detailed history of seizure symptoms, neuroimaging studies (such as MRI or CT scans), and electroencephalography (EEG) to record brain activity during and between seizures.

Treatment for complex partial epilepsy usually involves medication therapy with antiepileptic drugs (AEDs). In some cases, surgery may be recommended if medications are not effective in controlling seizures or if there is a structural lesion that can be safely removed. Other treatment options may include dietary modifications, such as the ketogenic diet, or vagus nerve stimulation.

Brain neoplasms, also known as brain tumors, are abnormal growths of cells within the brain. These growths can be benign (non-cancerous) or malignant (cancerous). Benign brain tumors typically grow slowly and do not spread to other parts of the body. However, they can still cause serious problems if they press on sensitive areas of the brain. Malignant brain tumors, on the other hand, are cancerous and can grow quickly, invading surrounding brain tissue and spreading to other parts of the brain or spinal cord.

Brain neoplasms can arise from various types of cells within the brain, including glial cells (which provide support and insulation for nerve cells), neurons (nerve cells that transmit signals in the brain), and meninges (the membranes that cover the brain and spinal cord). They can also result from the spread of cancer cells from other parts of the body, known as metastatic brain tumors.

Symptoms of brain neoplasms may vary depending on their size, location, and growth rate. Common symptoms include headaches, seizures, weakness or paralysis in the limbs, difficulty with balance and coordination, changes in speech or vision, confusion, memory loss, and changes in behavior or personality.

Treatment for brain neoplasms depends on several factors, including the type, size, location, and grade of the tumor, as well as the patient's age and overall health. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, or a combination of these approaches. Regular follow-up care is essential to monitor for recurrence and manage any long-term effects of treatment.

Supratentorial neoplasms refer to tumors that originate in the region of the brain located above the tentorium cerebelli, which is a dual layer of dura mater (the protective outer covering of the brain) that separates the cerebrum from the cerebellum. This area includes the cerebral hemispheres, basal ganglia, thalamus, hypothalamus, and pineal gland. Supratentorial neoplasms can be benign or malignant and may arise from various cell types such as neurons, glial cells, meninges, or blood vessels. They can cause a variety of neurological symptoms depending on their size, location, and rate of growth.

Cerebellar neoplasms refer to abnormal growths or tumors that develop in the cerebellum, which is the part of the brain responsible for coordinating muscle movements and maintaining balance. These tumors can be benign (non-cancerous) or malignant (cancerous), and they can arise from various types of cells within the cerebellum.

The most common type of cerebellar neoplasm is a medulloblastoma, which arises from primitive nerve cells in the cerebellum. Other types of cerebellar neoplasms include astrocytomas, ependymomas, and brain stem gliomas. Symptoms of cerebellar neoplasms may include headaches, vomiting, unsteady gait, coordination problems, and visual disturbances. Treatment options depend on the type, size, and location of the tumor, as well as the patient's overall health and age. Treatment may involve surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Graduate education typically refers to educational programs beyond the undergraduate level that lead to an advanced degree, such as a master's, doctoral, or professional degree. These programs usually require completion of a Bachelor's degree as a prerequisite and involve more specialized and in-depth study in a particular field. Graduate education may include coursework, research, examinations, and the completion of a thesis or dissertation. The specific requirements for graduate education vary depending on the field of study and the institution offering the degree program.

In a medical context, "faculty" most commonly refers to the inherent abilities or powers of a normal functioning part of the body or mind. For example, one might speak of the "faculties of perception" to describe the senses of sight, hearing, touch, taste, and smell. It can also refer to the teaching staff or body of instructors at a medical school or other educational institution. Additionally, it can be used more generally to mean a capability or skill, as in "the faculty of quick thinking."

I apologize for any confusion, but "students" is not a medical term. It refers to individuals who are engaged in studying or learning at an educational institution, such as a school, college, or university. If you have any questions related to medical terminology or concepts, I would be happy to help clarify those for you.

"Education, Pharmacy, Graduate" generally refers to the completion of a graduate-level program of study in the field of pharmacy. This type of education is typically pursued by individuals who already hold an undergraduate degree and wish to specialize in the preparation, dispensing, and proper use of medications.

In order to become a licensed pharmacist in the United States, for example, an individual must typically complete a Doctor of Pharmacy (Pharm.D.) program, which is a post-baccalaureate degree that typically takes four years to complete. During this time, students learn about various aspects of pharmacy practice, including drug therapy management, patient care, and communication skills. They also gain hands-on experience through internships and other experiential learning opportunities.

Graduates of pharmacy programs may go on to work in a variety of settings, including community pharmacies, hospitals, clinics, and long-term care facilities. They may also choose to pursue research or academic careers, working as professors or researchers in universities or research institutions.

The term "Faculty, Medical" generally refers to the faculty members who are involved in medical education and training within a medical school or academic institution. These individuals are responsible for teaching and instructing medical students, residents, and fellows in various areas of medical knowledge and clinical skills. They may hold positions such as professor, associate professor, assistant professor, or instructor, and they may specialize in a particular area of medicine such as internal medicine, surgery, pediatrics, or psychiatry. Medical faculty members may also be involved in research, patient care, and administrative duties within the institution.

Audiovisual aids are educational tools that utilize both visual and auditory senses to facilitate learning and communication. These aids can include various forms of technology such as projectors, televisions, computers, and mobile devices, as well as traditional materials like posters, charts, and models. In a medical context, audiovisual aids may be used in lectures, presentations, or patient education to help illustrate complex concepts, demonstrate procedures, or provide information in a clear and engaging way. They can be particularly useful for individuals who learn best through visual or auditory means, and can help to improve comprehension and retention of information.

I'm sorry for any confusion, but "teaching" is a general term that refers to the act of imparting knowledge or skills to others and is not a medical term. However, in the context of medical education, teaching refers to the instruction and training of medical students, residents, fellows, and other healthcare professionals to develop their knowledge, skills, and attitudes necessary for providing high-quality patient care. This can take place in various settings such as classrooms, clinical wards, simulation centers, or online platforms, and can involve a range of teaching methods including lectures, small group discussions, bedside teaching, case-based learning, and hands-on training.

"Ganglioglioma". St. Jude Children's Research Hospital. Retrieved March 8, 2023. "Ganglioglioma". St. Jude Children's Research ... Ganglioglioma is a rare, slow-growing primary central nervous system (CNS) tumor which most frequently occurs in the temporal ... Definitive treatment for ganglioglioma requires gross total surgical resection, and a good prognosis is generally expected when ... Histologically, ganglioglioma is composed of both neoplastic glial and ganglion cells which are disorganized, variably cellular ...
This mixed subunit expresses the glial nodules and components of ganglioglioma. Other findings suggest that DNTs require a ...
... a life-threatening complication after radical resection of a cervicomedullary ganglioglioma". Pediatric Neurosurgery. 41 (2): ...
The main difference between AG and ganglioglioma could be only AG shows enhancement over time. Compared to AG, astroblastoma ... Nevertheless, precise diagnosis of AG from other phenotypically similar gliomas (such as astroblastoma or ganglioglioma) is a ...
... and caused the infarction of a ganglioglioma, a benign spinal tumor. Turner underwent emergency surgery at the Royal Victoria ...
... that it was growing aggressively on her brain's left temporal lobe as a rare cancer called anaplastic astrocytoma ganglioglioma ...
Ganglioglioma and gangliocytoma Meningioangiomatosis Postencephalitic parkinsonism Subacute sclerosing panencephalitis (SSPE) ...
... ganglioglioma MeSH C04.557.465.625.600.380.400 - gliosarcoma MeSH C04.557.465.625.600.380.515 - medulloblastoma MeSH C04.557. ... ganglioglioma MeSH C04.557.470.670.380.400 - gliosarcoma MeSH C04.557.470.670.380.515 - medulloblastoma MeSH C04.557.470.670. ... ganglioglioma MeSH C04.557.580.625.600.380.400 - gliosarcoma MeSH C04.557.580.625.600.380.515 - medulloblastoma MeSH C04.557. ...
MN1-altered 1.5 Glioneuronal and neuronal tumours 1.5.1 Ganglioglioma 1.5.2 Desmoplastic infantile ganglioglioma / desmoplastic ...
NOS M9504/3 Spongioneuroblastoma M9505/1 Ganglioglioma, NOS M9505/3 Ganglioglioma, anaplastic M9506/1 Central neurocytoma ... astrocytoma M9411/3 Gemistocytic astrocytoma Gemistocytoma M9412/1 Desmoplastic infantile astrocytoma or ganglioglioma M9413/0 ...
Lytico-Bodig disease (Parkinson-dementia complex of Guam) Ganglioglioma and gangliocytoma Meningioangiomatosis Subacute ...
... acid transaminase deficiency Gamma-cystathionase deficiency Gamma-sarcoglycanopathy Gamstorp episodic adynamy Ganglioglioma ...
"Ganglioglioma". St. Jude Childrens Research Hospital. Retrieved March 8, 2023. "Ganglioglioma". St. Jude Childrens Research ... Ganglioglioma is a rare, slow-growing primary central nervous system (CNS) tumor which most frequently occurs in the temporal ... Definitive treatment for ganglioglioma requires gross total surgical resection, and a good prognosis is generally expected when ... Histologically, ganglioglioma is composed of both neoplastic glial and ganglion cells which are disorganized, variably cellular ...
The cerebellar location of ganglioglioma (GG) is exceptional. We report one case of a 27-year-old man who underwent an ... Cerebellar ganglioglioma Pan Afr Med J. 2012:12:12. Epub 2012 May 22. ... The cerebellar location of ganglioglioma (GG) is exceptional. We report one case of a 27-year-old man who underwent an ... Histological study after surgical removal, revealed a ganglioglioma tumor. Through this case and literature review, the authors ...
Ganglioglioma was first described by Courville in 1930 as a central nervous system neoplasm containing both astrocytic and ... encoded search term (Ganglioglioma Imaging) and Ganglioglioma Imaging What to Read Next on Medscape ... Ganglioglioma Imaging Updated: Feb 01, 2022 * Author: Anil Khosla, MBBS, MD; Chief Editor: James G Smirniotopoulos, MD more... ... Ganglioglioma tumor of the central nervous system: review of the literature and report of two cases. Arch Neurol Psych. 1930. ...
A ganglioglioma is low-grade tumor of mixed cell type. Learn more from Boston Childrens Hospital. ... What is a ganglioglioma?. A ganglioglioma is low-grade tumor of mixed cell type. It is very rare and contains properties of ... Ganglioglioma , Diagnosis & Treatments. How is ganglioglioma diagnosed?. A physician may order a number of different tests to ... How we care for ganglioglioma. Children and adolescents with ganglioglioma are treated at Dana-Farber/Boston Childrens Cancer ...
In the present study, we aim to determine the prevalence of BRAF V600E mutations in a series of ganglioglioma (GG) and ... 2). This was ganglioglioma, in which it was not possible to distinguish a weak immunostaining from a background staining. Thus ... In the present study, we aim to determine the prevalence of BRAF V600E mutations in a series of ganglioglioma (GG) and ... Due to the uniqueness of the clinical material, we focused our attention on rare brain tumor types-ganglioglioma (GG) and ...
Ganglioglioma. Gangliogliomas are rare, usually low-grade CNS tumors (WHO grade I). A minority of tumors show more aggressive ...
Information on Anaplastic ganglioglioma, which may include symptoms, causes, inheritance, treatments, orphan drugs, associated ... Anaplastic ganglioglioma (AGG) is a very rare type of brain tumor that is a type of ganglioglioma. In general, gangliogliomas ... Dont fight Anaplastic ganglioglioma alone!. Find your community on the free RareGuru App. Connect with caregivers and patients ... Dont fight Anaplastic ganglioglioma alone.. Find your community on the free RareGuru App. Connect with other caregivers and ...
Alectinib-responsive infantile anaplastic ganglioglioma with a novel VCL-ALK gene fusion. Pediatric Blood and Cancer. 2021 Sept ... Alectinib-responsive infantile anaplastic ganglioglioma with a novel VCL-ALK gene fusion. In: Pediatric Blood and Cancer. 2021 ... Alectinib-responsive infantile anaplastic ganglioglioma with a novel VCL-ALK gene fusion. / Yamamoto, Shunsuke; Koga, Yuhki; ... title = "Alectinib-responsive infantile anaplastic ganglioglioma with a novel VCL-ALK gene fusion", ...
Nasal ganglioglioma is a rare tumor, presenting in newborns, containing both neuronal and astrocytic components and that can be ... Ganglioglioma in the nasal cavity: a case report.. Yorgancılar E, Yıldırım M, Gün R, Büyükbayram H, Meriç F. Kulak Burun Bogaz ... Nasal ganglioglioma--difficulties in radiological imaging.. Niedzielska G, Niedzielski A, Kotowski M. Int J Pediatr ... Nasal ganglioglioma--difficulties in radiological imaging.. Niedzielska G, Niedzielski A, Kotowski M. Int J Pediatr ...
Do you qualify for these Anaplastic Ganglioglioma studies? Were researching treatments for 2023. ... Anaplastic Ganglioglioma is a type of brain tumor. UCSF is conducting a clinical trial for patients with this tumor. The trial ... Anaplastic Ganglioglioma clinical trials at UCSF 1 research study open to eligible people ... Our lead scientists for Anaplastic Ganglioglioma research studies include Alyssa T. Reddy. ...
Papilledema as the Presenting Sign of Pineal Ganglioglioma. Younes, Sami W; Charoenkijkajorn, Chaow; Pakravan, Mohammad; ... Papilledema as the Presenting Sign of Pineal Ganglioglioma. ...
Dive into the research topics of Novel suprasellar location of desmoplastic infantile astrocytoma and ganglioglioma: A single ... Novel suprasellar location of desmoplastic infantile astrocytoma and ganglioglioma: A single institutions experience. ...
Ganglioglioma (GG) and pilocytic astrocytoma (PA) represent the most frequent low-grade gliomas (LGG) occurring in paediatric ... del Bufalo, F., Carai, A., Figà-Talamanca, L. et al. Response of recurrent BRAFV600E mutated ganglioglioma to Vemurafenib as ... Ganglioglioma (GG) and pilocytic astrocytoma (PA) represent the most frequent low-grade gliomas (LGG) occurring in paediatric ... Ganglioglioma (GG) and pilocytic astrocytoma (PA) represent the most frequent low-grade gliomas (LGG) occurring in paediatric ...
Ganglioglioma. Gangliogliomas are the second most common form of mixed neuronal-glial tumours are are covered in detail on our ... Originally considered to be a type of ganglioglioma, a papillary glioneural tumour has been recognised as a distinct mixed ... Desmoplastic infantile astrocytoma and ganglioglioma. Previously classified as two different types of tumour, desmoplastic ... infantile astrocytoma and desmoplastic infantile ganglioglioma are considered so similar that they were grouped together by the ...
I am/have/hadganglioglioma. I am/have/hadaspermatogenic sterility. I am/have/hadhuman chorionic gonadotropin. ...
Desmoplastic infantile astrocytoma / ganglioglioma. *Polymorphous low-grade neuroepithelial tumor of the young ...
Desmoplastic infantile ganglioglioma (DIG), is a rare tumor arising mainly during the first two years of life. Molecular ... Desmoplastic infantile ganglioglioma (DIG), is a rare tumor arising mainly during the first 2 years of life. Molecular ... Desmoplastic infantile ganglioglioma (DIG), is a rare tumor arising mainly during the first 2 years of life. Non-infantile ... 2004). Desmoplastic Infantile Ganglioglioma: A Rare Tumor with an Unusual Presentation. Ann. Diagn. Pathol. 8, 280-283. doi: ...
Tumor classes and types included 1 Grade II astrocytoma, 1 pleomorphic xanthoastrocytoma, 1 ganglioglioma, and 2 glioneural ... WHO Grade I ganglioglioma. 1. CPS = complex partial seizures; FG = fusiform gyrus; FU = follow-up; PXA = pleomorphic ... Tumor classes and types included 1 Grade II astrocytoma, 1 pleomorphic xanthoastrocytoma, 1 ganglioglioma, and 2 glioneural ... Tumor classes and types included 1 Grade II astrocytoma, 1 pleomorphic xanthoastrocytoma, 1 ganglioglioma, and 2 glioneural ...
Ganglioglioma are usually small and noncancerous and develop slowly.. *Subependymal giant cell tumors may occur in children and ...
Atypical Calcified Ganglioglioma: A Rare Case Report (Articles) Seizo Yamashita, Luiz Antonio Resende, Fernanda M. P. Souza, ...
desmoplastic infantile ganglioglioma Australia. Sat Apr 15, 2017 1:03 am. Itsaimee. 0. Acinic cell carcinoma Mon Apr 24, 2017 ...
"Occult Pigmented Ganglioglioma in an Adult Male with Chronic Posttraumatic Epilepsy." ,i>Clinical Neuropathology,/i> 32 (3): ... "Occult Pigmented Ganglioglioma in an Adult Male with Chronic Posttraumatic Epilepsy." ,i>Clinical neuropathology,/i> 32.3 (2013 ... Occult pigmented ganglioglioma in an adult male with chronic posttraumatic epilepsy. ,i>Clinical Neuropathology,/i>, ,i>32,/i>( ... Occult pigmented ganglioglioma in an adult male with chronic posttraumatic epilepsy.,type:article,contentClass: ...
The histologic classification employed by the World Health Organization (WHO) for central nervous system (CNS) tumors, shown below, makes use of 4 grades. WHO histologic grading for CNS tumors Grade I: Lesions with low proliferative potential, a frequently discrete nature, and the possibility of cure following surgical resection alone Juve...
E, Ganglioglioma has large binucleated ganglion cells in a glial background. F, Pleomorphic xanthroastrocytoma with massive ... E, Ganglioglioma has large binucleated ganglion cells in a glial background. F, Pleomorphic xanthroastrocytoma with massive ... 2). Ganglioglioma shows large neoplastic ganglion-like cells with occasional bi-nucleation and a mixed glial neoplastic ... A, SRH image mosaic (center) of a ganglioglioma, WHO grade I, is shown with individual FOV tiles demarcated with dashed black ...
dAndrea, G.; Sessa, G.; Ferrante, L.: Ganglioglioma of the Right Lateral Ventricle Approached with Neuronavigation and ...
Friedrich, P., Forkel, S. J., Amiez, C., Balsters, J. H., Coulon, O., Fan, L., Goulas, A., Hadj-Bouziane, F., Hecht, E. E., Heuer, K., Jiang, T., Latzman, R. D., Liu, X., Loh, K. K., Patil, K. R., Lopez-Persem, A., Procyk, E., Sallet, J., Toro, R., Vickery, S., & 8 othersWeis, S., Wilson, CR. E., Xu, T., Zerbi, V., Eickoff, S. B., Margulies, DS. S., Mars, RB. B. & Thiebaut de Schotten, M., Mar 2021, In: NeuroImage. 228, 117685.. Research output: Contribution to journal › Article › peer-review ...
Flanagan, D. J., Amirkhah, R., Vincent, D. F., Gunduz, N., Gentaz, P., Cammareri, P., McCooey, A. J., McCorry, A. M. B., Fisher, N. C., Davis, H. L., Ridgway, R. A., Lohuis, J., Leach, J. D. G., Jackstadt, R., Gilroy, K., Mariella, E., Nixon, C., Clark, W., Hedley, A., Markert, E. K., & 19 othersStrathdee, D., Bartholin, L., Redmond, K. L., Kerr, E. M., Longley, D. B., Ginty, F., Cho, S., Coleman, H. G., Loughrey, M. B., Bardelli, A., Maughan, T. S., Campbell, A. D., Lawler, M., Leedham, S. J., Barry, S. T., Inman, G. J., van Rheenen, J., Dunne, P. D. & Sansom, O. J., 31 Jan 2023, In: Nature Communications. 14, p. 522. Research output: Contribution to journal › Article › peer-review ...
In January, Brody was diagnosed with a rare brain tumor called Anaplastic Ganglioglioma with a TRK mutation. Conventional ...
Epilepsy Outcome and Pathology Analysis for Ganglioglioma: A Series of 51 Pediatric Patients.. Pediatr Neurol. 2023;149:127-133 ...
Manni, F., Fonollà, R., van der Sommen, F., Zinger, S., Shan, C., Kho, E., Brouwer de Koning, S. G., Ruers, T. J. M. & de With, P. H. N., 27 Aug 2020, 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020. IEEE EMBS, p. 1169-1173 5 p. 9176543. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2020-July).. Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review ...
  • the presence of anaplastic changes in the glial component is considered to represent WHO grade III (anaplastic ganglioglioma). (wikipedia.org)
  • With the exception of WHO grade III anaplastic ganglioglioma, radiation therapy is generally regarded to have no role in the treatment of ganglioglioma. (wikipedia.org)
  • Adjuvant chemotherapy is also typically reserved for anaplastic ganglioglioma, but has been used anecdotally in partially resected low grade spinal cord gangliogliomas which show evidence of disease progression. (wikipedia.org)
  • Don't fight Anaplastic ganglioglioma alone. (rareguru.com)
  • Connect with other caregivers and patients with Anaplastic ganglioglioma and get the support you need. (rareguru.com)
  • Anaplastic ganglioglioma (AGG) is a very rare type of brain tumor that is a type of ganglioglioma . (rareguru.com)
  • Anaplastic Ganglioglioma is a type of brain tumor. (ucsf.edu)
  • In January, Brody was diagnosed with a rare brain tumor called Anaplastic Ganglioglioma with a TRK mutation. (nbcdfw.com)
  • In that study, patients with spinal cord ganglioglioma had a 3.5-fold higher relative risk of tumor recurrence compared to patients with supratentorial ganglioglioma. (wikipedia.org)
  • Histological study after surgical removal, revealed a ganglioglioma tumor. (nih.gov)
  • A ganglioglioma is low-grade tumor of mixed cell type. (childrenshospital.org)
  • In rare cases, ganglioglioma may transform into a higher grade, more malignant tumor. (childrenshospital.org)
  • Children and adolescents with ganglioglioma are treated at Dana-Farber/Boston Children's Cancer and Blood Disorders Center through the Brain Tumor Center , one of the largest and most experienced pediatric brain tumor treatment programs in the world. (childrenshospital.org)
  • Our brain tumor specialists have extensive expertise in treating all types of brain tumors, including ganglioglioma. (childrenshospital.org)
  • Due to the uniqueness of the clinical material, we focused our attention on rare brain tumor types-ganglioglioma (GG) and pilocytic astrocytoma (PA). (hindawi.com)
  • Nasal ganglioglioma is a rare tumor, presenting in newborns, containing both neuronal and astrocytic components and that can be endonasal, extranasal or both. (nih.gov)
  • Desmoplastic infantile ganglioglioma (DIG), is a rare tumor arising mainly during the first 2 years of life. (frontiersin.org)
  • Tumor classes and types included 1 Grade II astrocytoma, 1 pleomorphic xanthoastrocytoma, 1 ganglioglioma, and 2 glioneural tumors. (thejns.org)
  • Astrocytoma and ependymoma are more familiar intramedullary tumors which share many similar features to ganglioglioma, including T2 hyperintensity, enhancement, tumoral cysts, and cord edema. (wikipedia.org)
  • In the present study, we aim to determine the prevalence of BRAF V600E mutations in a series of ganglioglioma (GG) and pilocytic astrocytoma (PA) cases. (hindawi.com)
  • Ganglioglioma (GG) and pilocytic astrocytoma (PA) represent the most frequent low-grade gliomas (LGG) occurring in paediatric age. (biomedcentral.com)
  • They therefore contain abnormal neurones plus elements of one or more type of glioma brain tumour such as astrocytoma , oligodendroglioma and ganglioglioma . (braintumourresearch.org)
  • Longitudinal mutational analysis of a cerebellar pilocytic astrocytoma recurring as a ganglioglioma. (cdc.gov)
  • Malignant transformation of spinal ganglioglioma has been seen in only a select few cases. (wikipedia.org)
  • In fact, radiation therapy may induce malignant transformation of a recurrent ganglioglioma several years later. (wikipedia.org)
  • Hemangioblastoma and paraganglioma are less usual intramedullary tumors, but since they are more frequently encountered than ganglioglioma, they should also be included in the differential diagnosis. (wikipedia.org)
  • The histological examination of the residual lesion showed the presence, in addition to the glial component, of mature ganglion cells, leading to a diagnosis of ganglioglioma (GG) (Figure 2 ) with classical morphology, i.e. neoplastic astrocytes and ganglion cells with dysplastic, binucleated neuron, embedded in tissue with eosinhophilic granular body and lymphocytic intratumoral infiltrate. (biomedcentral.com)
  • It is nearly impossible to differentiate ganglioglioma from other more common intramedullary neoplasms based on imaging alone. (wikipedia.org)
  • The recommended treatment for progressive or recurrent ganglioglioma is radiation therapy. (childrenshospital.org)
  • Histologically, ganglioglioma is composed of both neoplastic glial and ganglion cells which are disorganized, variably cellular, and non-infiltrative. (wikipedia.org)
  • The presence of neoplastic ganglion cells forming abnormal clusters, the presence of binucleation and dysmorphic neurons are helpful clues favoring ganglioglioma over glioma. (wikipedia.org)
  • Rarely, the enhancement pattern of the ganglioglioma may mimic a vascular malformation, and catheter angiography is required to exclude a vascular malformation. (medscape.com)
  • reviewing several patients with resected spinal cord ganglioglioma, the 5- and 10-year survival rates after total resection were 89% and 83%, respectively. (wikipedia.org)
  • Epilepsy Outcome and Pathology Analysis for Ganglioglioma: A Series of 51 Pediatric Patients. (amedeo.com)
  • In the earlier research, a patient with a BRAFV600E brainstem ganglioglioma was successfully treated by repurposing the autophagy inhibitor chloroquine (CQ), which is an inexpensive, FDA-approved drug used to treat malaria. (childrenscolorado.org)
  • Ganglioglioma was first described by Courville in 1930 as a central nervous system neoplasm containing both astrocytic and neuronal components. (medscape.com)
  • The glial component of ganglioglioma includes fibrillary astrocytes with varying degrees of cellular atypia. (wikipedia.org)
  • The cerebellar location of ganglioglioma (GG) is exceptional. (nih.gov)
  • Axial magnetic resonance images (T1-weighted, T1-weighted with contrast, and T2-weighted) demonstrate a left superior medial frontal mixed solid and cystic mass that is surgically proven and typical ganglioglioma. (medscape.com)
  • En revanche, les patients de moins de cinq ans et ceux avec un diagnostic de cancer provisoire posé initialement bénéficiaient du délai total médian le plus court. (who.int)
  • Nous suggérons de mettre en place des programmes de formation médicale continue, d'améliorer l'accès aux services de diagnostic, et de faciliter l'orientation-recours de façon à donner la priorité aux patients suspects de cancer et ainsi raccourcir le délai de diagnostic. (who.int)
  • Zaky W, Patil SS, Park M, Liu D, Wang WL, Wani KM, Calle S, Ketonen L, Khatua S . Ganglioglioma in children and young adults: single institution experience and review of the literature. (mdanderson.org)
  • Ganglioglioma in the nasal cavity: a case report. (nih.gov)
  • Definitive treatment for ganglioglioma requires gross total surgical resection, and a good prognosis is generally expected when this is achieved. (wikipedia.org)
  • What are the treatment options for ganglioglioma? (childrenshospital.org)
  • Desmoplastic cerebral astrocytoma of infancy (DCAI) and desmoplastic infantile ganglioglioma (DIGG) are present as large, superficial, usually benign astrocytomas that most commonly affect children under the age of two years. (encyclopedia.com)
  • 1. Anaplastic oligodendroglioma with ganglioglioma-like maturation. (nih.gov)
  • Other types of gliomas that are less common than pilocytic astrocytomas, but still grow slowly, include tectal glioma, oligodendroglioma, ganglioglioma, and pleomorphic xanthroastrocytoma. (akronchildrens.org)
  • Astrocytoma and ependymoma are more familiar intramedullary tumors which share many similar features to ganglioglioma, including T2 hyperintensity, enhancement, tumoral cysts, and cord edema. (wikipedia.org)
  • Hemangioblastoma and paraganglioma are less usual intramedullary tumors, but since they are more frequently encountered than ganglioglioma, they should also be included in the differential diagnosis. (wikipedia.org)
  • Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. (arkanalabs.com)
  • Several novel NTRK fusions were observed in rare tumors types including ganglioglioma and PTCs. (cancertherapyadvisor.com)
  • 12. Pleomorphic xanthoastrocytoma as a component of a temporal lobe cystic ganglioglioma: a case report. (nih.gov)
  • Young adult female with a ganglioglioma (GG) in the right temporal lobe. (arkanalabs.com)
  • Ildan F, Tuna M, Gocer IA et al (2001) Intracerebral ganglioglioma: clinical and radiological study of eleven surgically treated cases with follow-up. (springer.com)
  • The clinicopathological features of ganglioglioma with CD34 expression and BRAF mutation in patients with epilepsy. (blogspot.com)
  • Axial magnetic resonance images (T1-weighted, T1-weighted with contrast, and T2-weighted) demonstrate a left superior medial frontal mixed solid and cystic mass that is surgically proven and typical ganglioglioma. (medscape.com)
  • Rarely, the enhancement pattern of the ganglioglioma may mimic a vascular malformation, and catheter angiography is required to exclude a vascular malformation. (medscape.com)
  • Ganglioglioma of brain stem and cervicomedullary junction: A 50years review of literature. (cornell.edu)
  • Ganglioglioma was first described by Courville in 1930 as a central nervous system neoplasm containing both astrocytic and neuronal components. (medscape.com)
  • Here, we report a case study of a familial MEN1 syndrome with a central nervous system ganglioglioma, a manifestation that has not been characterized so far. (bvsalud.org)
  • The girl also presented with hydrocephalus caused by ganglioglioma of the central nervous system. (bvsalud.org)
  • Zaky W, Patil SS, Park M, Liu D, Wang WL, Wani KM, Calle S, Ketonen L, Khatua S . Ganglioglioma in children and young adults: single institution experience and review of the literature. (mdanderson.org)

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