Gastroparesis. Medical search. Web

Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.

The evacuation of food from the stomach into the duodenum.

c-Kit positive cells related to SMOOTH MUSCLE CELLS that are intercalated between the autonomic nerves and the effector smooth muscle cells of the GASTROINTESTINAL TRACT. Different phenotypic classes play roles as pacemakers, mediators of neural inputs, and mechanosensors.

Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion.

A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)

An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.

Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Drugs used in the treatment of movement disorders. Most of these act centrally on dopaminergic or cholinergic systems. Among the most important clinically are those used for the treatment of Parkinson disease (ANTIPARKINSON AGENTS) and those for the tardive dyskinesias.

Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.

A variety of surgical reconstructive procedures devised to restore gastrointestinal continuity, The two major classes of reconstruction are the Billroth I (gastroduodenostomy) and Billroth II (gastrojejunostomy) procedures.

Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.

The motor activity of the GASTROINTESTINAL TRACT.

Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.

Pathological processes involving the STOMACH.

Methods and procedures for the diagnosis of diseases or dysfunction of the digestive system or its organs or demonstration of their physiological processes.

The region of the STOMACH at the junction with the DUODENUM. It is marked by the thickening of circular muscle layers forming the pyloric sphincter to control the opening and closure of the lumen.

The forcible expulsion of the contents of the STOMACH through the MOUTH.

A dopamine D2 antagonist that is used as an antiemetic.

The region in the abdomen extending from the thoracic DIAPHRAGM to the plane of the superior pelvic aperture (pelvic inlet). The abdominal cavity contains the PERITONEUM and abdominal VISCERA, as well as the extraperitoneal space which includes the RETROPERITONEAL SPACE.

A peptide of about 22-amino acids isolated from the DUODENUM. At low pH it inhibits gastric motor activity, whereas at high pH it has a stimulating effect.

Natural history of diabetic gastroparesis. (1/173)

OBJECTIVE: The major aim of this study was to evaluate the prognosis of diabetic gastroparesis. RESEARCH DESIGN AND METHODS: Between 1984 and 1989, 86 outpatients with diabetes (66 type 1, 20 type 2; 40 male, 46 female) underwent assessment of solid and liquid gastric emptying and esophageal transit (by scintigraphy), gastrointestinal symptoms (by questionnaire), autonomic nerve function (by cardiovascular reflex tests), and glycemic control (by HbAlc and blood glucose concentrations during gastric emptying measurement). These patients were followed up in 1998. RESULTS: Of the 86 patients, solid gastric emptying (percentage of retention at 100 min) was delayed in 48 (56%) patients and liquid emptying (50% emptying time) was delayed in 24 (28%) patients. At follow-up in 1998, 62 patients were known to be alive, 21 had died, and 3 were lost to follow-up. In the group who had died, duration of diabetes (P = 0.048), score for autonomic neuropathy (P = 0.046), and esophageal transit (P = 0.032) were greater than in those patients who were alive, but there were no differences in gastric emptying between the two groups. Of the 83 patients who could be followed up, 32 of the 45 patients (71%) with delayed solid emptying and 18 of the 24 patients (75%) with delay in liquid emptying were alive. After adjustment for the effects of other factors that showed a relationship with the risk of dying, there was no significant relationship between either gastric emptying or esophageal transit and death. CONCLUSIONS: In this relatively large cohort of outpatients with diabetes, there was no evidence that gastroparesis was associated with a poor prognosis. (+info)

Gastric emptying rate assessment based on the proportion of intra-abdominal radioactivity in the stomach. (2/173)

Using scintigraphic techniques, the rate of gastric emptying is calculated by quantifying the absolute radioactivity within a gastric region of interest (intragastric method) with the time of meal completion considered 100% retention. However, this technique has significant limitations arising from subject movement and radionuclide gamma-ray attenuation, which may render curve fitting difficult, particularly in patients with gastroparesis. In an attempt to minimize these limitations, we have expressed the intragastric content as a percentage of the total abdominal radioactivity (abdominal method) and compared these two methods. METHODS: Forty-five subjects in a sitting position consumed a meal consisting of two fried eggs labeled with 99mTc, two slices of toast and 300 mL 5% glucose water (412 kcal). Data were acquired at a rate of one frame every 5 min from the left anterior oblique view. Using the two methods, the intragastric retention ratios at 30, 60, 90, 120 and 240 min and the 50% emptying time (T50) were obtained from both observation and calculation by power exponential fit. R2, representing goodness of fit of the nonlinear curve fitting, was calculated. RESULTS: There were no differences in the calculated values of T50 between the two methods. Quantitative estimates of T50 by extrapolation of a power exponential fit were feasible in 42 of the 45 subjects when the abdominal method was used, compared with only 29 of the 45 subjects when the intragastric method was used. In the 23 subjects with delayed emptying, quantitative estimates of T50 were feasible in 20 subjects when the abdominal method was used, compared with 7 subjects when the intragastric method was used. Using the abdominal method as opposed to the intragastric method also significantly improved R2. The difference between observed values and estimated values of T50 and intragastric retention ratios at 30, 90 and 120 min was smaller using the abdominal method. CONCLUSION: Scintigraphic measurement of gastric emptying calculated using the proportion of the abdominal radioactivity in the stomach offers substantial advantages over conventional methods, particularly in patients with gastroparesis. (+info)

Measurement of gastric emptying by standardized real-time ultrasonography in healthy subjects and diabetic patients. (3/173)

The aim of this study was to simplify and standardize a reproducible, well-tolerated and clinically applicable method for the assessment of gastric emptying rate by real-time ultrasonography. A total of 33 subjects were examined, including 19 healthy subjects and 14 patients with insulin-dependent diabetes mellitus and clinically suspected delayed gastric emptying. Measurements of the gastric antrum were taken in the supine position and in relation to internal landmarks to obtain a standardized cross-sectional image producing the area of a selected slice of the antrum. Diabetic patients were examined on the condition that the fasting blood glucose level was 3.5 to 9.0 mmol/l. Gastric emptying rate was estimated and expressed as the percentage reduction in antral cross-sectional area from 15 to 90 min after the ingestion of a standardized semisolid breakfast meal (300 g rice pudding, 330 kcal). Interobserver and intraobserver measurement errors were assessed, as was the significance of age and sex on gastric emptying. In comparison to healthy subjects, diabetic patients showed significantly wider median values of the 90 min postprandial antral area, but only a mild tendency toward greater dilation of the gastric antrum prior to and 15 min after meal ingestion. The median value of gastric emptying rate in these diabetic patients was estimated at 29%, which was less than half of that in the healthy subjects (63%). Statistically the difference was highly significant. Interpersonal variability of gastric emptying rate and antral areas was large for both groups. Measurements of gastric emptying rate gave highly reproducible results on separate days and from different observers (interobserver systematic measurement error 0.3% and random measurement error 10.9%; intraobserver systematic measurement error 3.6% and random measurement error 9.5%). No difference in gastric emptying rate was found related to age or sex. We conclude that the use of standardized real-time ultrasonography to determine gastric antral cross-sectional area in a single section of the stomach is a valid method for estimating gastric emptying rate. (+info)

Evaluation and management of dyspepsia. (4/173)

Dyspepsia, often defined as chronic or recurrent discomfort centered in the upper abdomen, can be caused by a variety of conditions. Common etiologies include peptic ulcers and gastroesophageal reflux. Serious causes, such as gastric and pancreatic cancers, are rare but must also be considered. Symptoms of possible causes often overlap, which can make initial diagnosis difficult. In many patients, a definite cause is never established. The initial evaluation of patients with dyspepsia includes a thorough history and physical examination, with special attention given to elements that suggest the presence of serious disease. Endoscopy should be performed promptly in patients who have "alarm symptoms" such as melena or anorexia. Optimal management remains controversial in young patients who do not have alarm symptoms. Although management should be individualized, a cost-effective initial approach is to test for Helicobacter pylori and treat the infection if the test is positive. If the H. pylori test is negative, empiric therapy with a gastric acid suppressant or prokinetic agent is recommended. If symptoms persist or recur after six to eight weeks of empiric therapy, endoscopy should be performed. (+info)

Comparative effects of levosulpiride and cisapride on gastric emptying and symptoms in patients with functional dyspepsia and gastroparesis. (5/173)

BACKGROUND: The efficacy of several prokinetic drugs on dyspeptic symptoms and on gastric emptying rates are well-established in patients with functional dyspepsia, but formal studies comparing different prokinetic drugs are lacking. AIM: To compare the effects of chronic oral administration of cisapride and levosulpiride in patients with functional dyspepsia and delayed gastric emptying. METHODS: In a double-blind crossover comparison, the effects of a 4-week administration of levosulpiride (25 mg t.d.s.) and cisapride (10 mg t.d.s.) on the gastric emptying rate and on symptoms were evaluated in 30 dyspeptic patients with functional gastroparesis. At the beginning of the study and after levosulpiride or cisapride treatment, the gastric emptying time of a standard meal was measured by 13C-octanoic acid breath test. Gastrointestinal symptom scores were also evaluated. RESULTS: The efficacy of levosulpiride was similar to that of cisapride in significantly shortening (P < 0.001) the t1/2 of gastric emptying. No significant differences were observed between the two treatments with regards to improvements in total symptom scores. However, levosulpiride was significantly more effective (P < 0.01) than cisapride in improving the impact of symptoms on the patients' every-day activities and in improving individual symptoms such as nausea, vomiting and early postprandial satiety. CONCLUSION: The efficacy of levosulpiride and cisapride in reducing gastric emptying times with no relevant side-effects is similar. The impact of symptoms on patients' everyday activities and the improvement of some symptoms such as nausea, vomiting and early satiety was more evident with levosulpiride than cisapride. (+info)

Effects of fedotozine on gastric emptying and upper gastrointestinal symptoms in diabetic gastroparesis. (6/173)

BACKGROUND: Delayed gastric emptying and upper gastrointestinal symptoms occur frequently in patients with diabetes mellitus. AIM: To evaluate the effects of fedotozine on gastric emptying and gastrointestinal symptoms in diabetic gastroparesis. METHODS: Thirty-one diabetic patients (20 type 1, 11 type 2) with gastroparesis were randomized to receive fedotozine (30 mg as the tartrate) or placebo t.d.s. Measurements of gastric emptying (100 g ground beef labelled with 20 MBq 99mTc-sulphur colloid chicken liver and 150 mL 10% dextrose labelled with 10 MBq 113mIn-DTPA) and gastrointestinal symptoms were performed before and after 12-16 days of treatment. Data are the mean +/- s.d. RESULTS: Of the 31 patients enrolled, two were excluded from analysis. Data from the remaining 29 patients (18 type 1, 11 type 2; 22 female, seven male), aged 42.7 +/- 11.1 years (of whom 14 were randomized to fedotozine and 15 to placebo), were analysed. Fedotozine had no effect on either gastric emptying (solid retention at 100 min; fedotozine: baseline, 84 +/- 15%; treatment, 73 +/- 23% vs. placebo: baseline, 83 +/- 10%; treatment, 70 +/- 20%) or liquid 50% emptying time (fedotozine: baseline, 59 +/- 32 min; treatment, 58 +/- 38 min vs. placebo: baseline, 44 +/- 9 min; treatment, 43 +/- 21 min) or gastrointestinal symptoms (fedotozine: baseline, 4.4 +/- 2.9; treatment, 4.1 +/- 3.9 vs. placebo: baseline, 4.9 +/- 4.2; treatment, 4.8 +/- 3.9). CONCLUSIONS: Fedotozine has no effect on gastric emptying in patients with diabetic gastroparesis. (+info)

Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis. (7/173)

Patients with long-standing diabetes commonly suffer from gastric neuromuscular dysfunction (gastropathy) causing symptoms ranging from postprandial bloating to recurrent vomiting. Autonomic neuropathy is generally believed to be responsible for diabetic gastropathy and the underlying impairments in gastric emptying (gastroparesis) and receptive relaxation, but the specific mechanisms have not been elucidated. Recently, it has been recognized that interstitial cells of Cajal generate electrical pacemaker activity and mediate motor neurotransmission in the stomach. Loss or defects in interstitial cells could contribute to the development of diabetic gastroparesis. Gastric motility was characterized in spontaneously diabetic NOD/LtJ mice by measuring gastric emptying and by monitoring spontaneous and induced electrical activity in circular smooth muscle cells. Interstitial cells of Cajal were studied by Kit immunofluorescence and transmission electron microscopy. Diabetic mice developed delayed gastric emptying, impaired electrical pacemaking, and reduced motor neurotransmission. Interstitial cells of Cajal were greatly reduced in the distal stomach, and the normally close associations between these cells and enteric nerve terminals were infrequent. Our observations suggest that damage to interstitial cells of Cajal may play a key role in the pathogenesis of diabetic gastropathy. (+info)

Gastroparesis following bone marrow transplantation. (8/173)

Patients often develop nausea, vomiting and bloating after bone marrow transplantation (BMT). These symptoms may interfere with nutrition and the ability to take oral medications. Gastroparesis is a recognized cause of these symptoms in non-transplant patients but less is known about patients who undergo BMT. Between January 1996 and March 1997, a total of 151 patients underwent BMT. Eighteen patients (12%) developed persistent symptoms suggestive of gastroparesis (persistent nausea, vomiting or bloating). Scintigraphic gastric emptying studies were performed to assess for gastroparesis. Prokinetic agents were administered at the time of study. The records on these patients were compared with those of all other patients undergoing BMT during the same time period without these symptoms. Nine patients who demonstrated delayed gastric emptying were further evaluated with esophagastroduodenoscopy and biopsy. Biopsy samples were reviewed for evidence of graft-versus-host disease (GVHD). Fourteen of 18 patients demonstrated delayed gastric emptying and most responded to prokinetic agents given at the time of study. Age, conditioning regimen, cytomegalovirus antigenemia and acute GVHD did not appear to be associated with the development of gastroparesis. Allogeneic BMT recipients were at higher risk than autologous BMT patients (26% vs 0%, P < 0.0001). of allogeneic bmt recipients, there was a nonsignificant trend of patients receiving tacrolimus to be less likely to experience gastroparesis than those receiving cyclosporine (27% vs 48%, P = 0.08). For the nine patients undergoing upper endoscopy, GVHD on gastric biopsy was an uncommon finding and was mild when present. Gastroparesis appears to be a common cause of nausea, vomiting and bloating following allogeneic BMT. This may occur less often with tacrolimus than cyclosporine because of the former agent's prokinetic properties. Patients usually respond to prokinetic drugs at the time of scintigraphy. GVHD and CMV infection do not appear to be major contributing factors. (+info)

Gastroparesis is a gastrointestinal disorder that affects the stomach's normal motility, resulting in the delayed emptying of food from the stomach into the small intestine. The term "gastroparesis" literally means "stomach paralysis," although the stomach doesn't actually become paralyzed in this condition. Instead, the muscles of the stomach wall become weakened or damaged, leading to a decrease in their ability to contract and push food through the digestive tract effectively.

The causes of gastroparesis can vary, but some common reasons include diabetes (both type 1 and type 2), viral infections, surgery involving the vagus nerve (which controls stomach muscle contractions), certain medications (such as narcotics, antidepressants, and high blood pressure drugs), gastroesophageal reflux disease (GERD), scleroderma, Parkinson's disease, multiple sclerosis, and Amyloidosis.

Symptoms of gastroparesis may include nausea, vomiting, feeling full quickly after starting to eat, bloating, heartburn, abdominal pain, lack of appetite, and unintended weight loss. These symptoms can significantly impact a person's quality of life and make it difficult for them to maintain proper nutrition.

Diagnosis typically involves a thorough medical history, physical examination, and various tests such as upper endoscopy, gastric emptying studies (such as the scintigraphy scan), and manometry to assess stomach muscle function. Treatment options may include dietary modifications, medications to stimulate stomach contractions or reduce symptoms like nausea and vomiting, botulinum toxin injections, electrical stimulation of the stomach muscles, or, in severe cases, feeding tubes or surgery.

Gastric emptying is the process by which the stomach empties its contents into the small intestine. In medical terms, it refers to the rate and amount of food that leaves the stomach and enters the duodenum, which is the first part of the small intestine. This process is regulated by several factors, including the volume and composition of the meal, hormonal signals, and neural mechanisms. Abnormalities in gastric emptying can lead to various gastrointestinal symptoms and disorders, such as gastroparesis, where the stomach's ability to empty food is delayed.

Interstitial Cells of Cajal (ICCs) are specialized cells found in the walls of the gastrointestinal tract, as well as in other organs such as the urinary and vascular systems. They play a crucial role in regulating the motility of the digestive system by acting as pacemakers and mediators of nerve impulses that control muscle contractions. ICCs have a unique morphology, characterized by numerous extensions and a large number of mitochondria, which allow them to generate electrical signals and communicate with surrounding cells. They are named after Santiago Ramón y Cajal, the Spanish histologist who first described these cells in the late 19th century.

Gastrointestinal agents are a class of pharmaceutical drugs that affect the gastrointestinal (GI) tract, which includes the organs involved in digestion such as the mouth, esophagus, stomach, small intestine, large intestine, and anus. These agents can have various effects on the GI tract, including:

1. Increasing gastric motility (promoting bowel movements) - laxatives, prokinetics
2. Decreasing gastric motility (reducing bowel movements) - antidiarrheal agents
3. Neutralizing gastric acid - antacids
4. Reducing gastric acid secretion - H2-blockers, proton pump inhibitors
5. Protecting the mucosal lining of the GI tract - sucralfate, misoprostol
6. Relieving symptoms associated with GI disorders such as bloating, abdominal pain, and nausea - antispasmodics, antiemetics

Examples of gastrointestinal agents include:

* Laxatives (e.g., psyllium, docusate)
* Prokinetics (e.g., metoclopramide)
* Antacids (e.g., calcium carbonate, aluminum hydroxide)
* H2-blockers (e.g., ranitidine, famotidine)
* Proton pump inhibitors (e.g., omeprazole, lansoprazole)
* Sucralfate
* Misoprostol
* Antispasmodics (e.g., hyoscyamine, dicyclomine)
* Antiemetics (e.g., ondansetron, promethazine)

It is important to note that gastrointestinal agents can have both therapeutic and adverse effects, and their use should be based on a careful evaluation of the patient's condition and medical history.

Cisapride is a medication that was used to treat gastrointestinal motility disorders, such as gastroparesis and constipation. It belongs to a class of drugs called "prokinetic agents" which work by increasing the contractions or movements of the muscles in the digestive tract, thereby helping to move food and waste through the system more efficiently.

Cisapride was first approved for use in the United States in 1993, but its use was later restricted due to concerns about serious side effects, including cardiac arrhythmias (irregular heartbeats) and interactions with other medications. In 2000, the U.S. Food and Drug Administration (FDA) requested that cisapride be withdrawn from the market due to these safety concerns.

While cisapride is no longer available for use in many countries, it may still be used in some cases under strict guidelines and monitoring conditions. It is important to note that the use of cisapride should only be initiated and monitored by a healthcare professional, and patients should inform their doctor about all other medications they are taking to avoid potential interactions.

In anatomical terms, the stomach is a muscular, J-shaped organ located in the upper left portion of the abdomen. It is part of the gastrointestinal tract and plays a crucial role in digestion. The stomach's primary functions include storing food, mixing it with digestive enzymes and hydrochloric acid to break down proteins, and slowly emptying the partially digested food into the small intestine for further absorption of nutrients.

The stomach is divided into several regions, including the cardia (the area nearest the esophagus), the fundus (the upper portion on the left side), the body (the main central part), and the pylorus (the narrowed region leading to the small intestine). The inner lining of the stomach, called the mucosa, is protected by a layer of mucus that prevents the digestive juices from damaging the stomach tissue itself.

In medical contexts, various conditions can affect the stomach, such as gastritis (inflammation of the stomach lining), peptic ulcers (sores in the stomach or duodenum), gastroesophageal reflux disease (GERD), and stomach cancer. Symptoms related to the stomach may include abdominal pain, bloating, nausea, vomiting, heartburn, and difficulty swallowing.

Diabetic neuropathies refer to a group of nerve disorders that are caused by diabetes. High blood sugar levels can injure nerves throughout the body, but diabetic neuropathies most commonly affect the nerves in the legs and feet.

There are four main types of diabetic neuropathies:

1. Peripheral neuropathy: This is the most common type of diabetic neuropathy. It affects the nerves in the legs and feet, causing symptoms such as numbness, tingling, burning, or shooting pain.
2. Autonomic neuropathy: This type of neuropathy affects the autonomic nerves, which control involuntary functions such as heart rate, blood pressure, digestion, and bladder function. Symptoms may include dizziness, fainting, digestive problems, sexual dysfunction, and difficulty regulating body temperature.
3. Proximal neuropathy: Also known as diabetic amyotrophy, this type of neuropathy affects the nerves in the hips, thighs, or buttocks, causing weakness, pain, and difficulty walking.
4. Focal neuropathy: This type of neuropathy affects a single nerve or group of nerves, causing symptoms such as weakness, numbness, or pain in the affected area. Focal neuropathies can occur anywhere in the body, but they are most common in the head, torso, and legs.

The risk of developing diabetic neuropathies increases with the duration of diabetes and poor blood sugar control. Other factors that may contribute to the development of diabetic neuropathies include genetics, age, smoking, and alcohol consumption.

Anti-dyskinetic agents are a class of medications that are used to treat or manage dyskinesias, which are involuntary movements or abnormal muscle contractions. These medications work by blocking or reducing the activity of dopamine, a neurotransmitter in the brain that is involved in movement control.

Dyskinetic symptoms can occur as a side effect of long-term use of levodopa therapy in patients with Parkinson's disease. Anti-dyskinetic agents such as amantadine, anticholinergics, and dopamine agonists may be used to manage these symptoms.

Amantadine works by increasing the release of dopamine and blocking its reuptake, which can help reduce dyskinesias. Anticholinergic medications such as trihexyphenidyl and benztropine work by blocking the action of acetylcholine, another neurotransmitter that can contribute to dyskinesias. Dopamine agonists such as pramipexole and ropinirole mimic the effects of dopamine in the brain and can help reduce dyskinesias by reducing the dose of levodopa required for symptom control.

It is important to note that anti-dyskinetic agents may have side effects, and their use should be carefully monitored by a healthcare provider.

Electric stimulation therapy, also known as neuromuscular electrical stimulation (NMES) or electromyostimulation, is a therapeutic treatment that uses electrical impulses to stimulate muscles and nerves. The electrical signals are delivered through electrodes placed on the skin near the target muscle group or nerve.

The therapy can be used for various purposes, including:

1. Pain management: Electric stimulation can help reduce pain by stimulating the release of endorphins, which are natural painkillers produced by the body. It can also help block the transmission of pain signals to the brain.
2. Muscle rehabilitation: NMES can be used to prevent muscle atrophy and maintain muscle tone in individuals who are unable to move their muscles due to injury or illness, such as spinal cord injuries or stroke.
3. Improving circulation: Electric stimulation can help improve blood flow and reduce swelling by contracting the muscles and promoting the movement of fluids in the body.
4. Wound healing: NMES can be used to promote wound healing by increasing blood flow, reducing swelling, and improving muscle function around the wound site.
5. Muscle strengthening: Electric stimulation can be used to strengthen muscles by causing them to contract and relax repeatedly, which can help improve muscle strength and endurance.

It is important to note that electric stimulation therapy should only be administered under the guidance of a trained healthcare professional, as improper use can cause harm or discomfort.

Gastroenterostomy is a surgical procedure that creates an anastomosis (a connection or junction) between the stomach and the small intestine, usually between the stomach's lesser curvature and the jejunum (the second part of the small intestine). This procedure is often performed to bypass a diseased or obstructed portion of the gastrointestinal tract, such as in the case of gastric ulcers, tumors, or other conditions that prevent normal digestion and absorption.

There are different types of gastroenterostomy procedures, including:
1. Billroth I (or "gastroduodenostomy"): The stomach is connected directly to the duodenum (the first part of the small intestine).
2. Billroth II (or "gastrojejunostomy"): The stomach is connected to the jejunum, bypassing the duodenum.
3. Roux-en-Y gastrojejunostomy: A more complex procedure in which a portion of the jejunum is separated and reconnected further down the small intestine, creating a Y-shaped configuration. This type of gastroenterostomy is often used in bariatric surgery for weight loss.

The choice of gastroenterostomy technique depends on the specific medical condition being treated and the patient's overall health status.

Gastric dilatation, also known as stomach dilation or distention, refers to the abnormal enlargement or expansion of the stomach. This condition often occurs when the stomach fills with gas, food, or fluids and is unable to empty properly. Gastric dilatation can be caused by various factors such as overeating, swallowing excessive air, gastroparesis (delayed gastric emptying), intestinal obstruction, or certain medical conditions like hiatal hernia or pregnancy.

In severe cases, gastric dilatation may lead to gastric volvulus, where the stomach twists on itself, cutting off its blood supply and leading to ischemia and necrosis of the stomach tissue. This is a life-threatening condition that requires immediate medical attention. Symptoms of gastric dilatation include abdominal pain, bloating, vomiting, loss of appetite, and difficulty breathing.

Gastrointestinal motility refers to the coordinated muscular contractions and relaxations that propel food, digestive enzymes, and waste products through the gastrointestinal tract. This process involves the movement of food from the mouth through the esophagus into the stomach, where it is mixed with digestive enzymes and acids to break down food particles.

The contents are then emptied into the small intestine, where nutrients are absorbed, and the remaining waste products are moved into the large intestine for further absorption of water and electrolytes and eventual elimination through the rectum and anus.

Gastrointestinal motility is controlled by a complex interplay between the autonomic nervous system, hormones, and local reflexes. Abnormalities in gastrointestinal motility can lead to various symptoms such as bloating, abdominal pain, nausea, vomiting, diarrhea, or constipation.

Diabetes complications refer to a range of health issues that can develop as a result of poorly managed diabetes over time. These complications can affect various parts of the body and can be classified into two main categories: macrovascular and microvascular.

Macrovascular complications include:

* Cardiovascular disease (CVD): People with diabetes are at an increased risk of developing CVD, including coronary artery disease, peripheral artery disease, and stroke.
* Peripheral arterial disease (PAD): This condition affects the blood vessels that supply oxygen and nutrients to the limbs, particularly the legs. PAD can cause pain, numbness, or weakness in the legs and may increase the risk of amputation.

Microvascular complications include:

* Diabetic neuropathy: This is a type of nerve damage that can occur due to prolonged high blood sugar levels. It commonly affects the feet and legs, causing symptoms such as numbness, tingling, or pain.
* Diabetic retinopathy: This condition affects the blood vessels in the eye and can cause vision loss or blindness if left untreated.
* Diabetic nephropathy: This is a type of kidney damage that can occur due to diabetes. It can lead to kidney failure if not managed properly.

Other complications of diabetes include:

* Increased risk of infections, particularly skin and urinary tract infections.
* Slow healing of wounds, which can increase the risk of infection and amputation.
* Gum disease and other oral health problems.
* Hearing impairment.
* Sexual dysfunction.

Preventing or managing diabetes complications involves maintaining good blood sugar control, regular monitoring of blood glucose levels, following a healthy lifestyle, and receiving routine medical care.

Stomach diseases refer to a range of conditions that affect the stomach, a muscular sac located in the upper part of the abdomen and is responsible for storing and digesting food. These diseases can cause various symptoms such as abdominal pain, nausea, vomiting, heartburn, indigestion, loss of appetite, and bloating. Some common stomach diseases include:

1. Gastritis: Inflammation of the stomach lining that can cause pain, irritation, and ulcers.
2. Gastroesophageal reflux disease (GERD): A condition where stomach acid flows back into the esophagus, causing heartburn and damage to the esophageal lining.
3. Peptic ulcers: Open sores that develop on the lining of the stomach or duodenum, often caused by bacterial infections or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).
4. Stomach cancer: Abnormal growth of cancerous cells in the stomach, which can spread to other parts of the body if left untreated.
5. Gastroparesis: A condition where the stomach muscles are weakened or paralyzed, leading to difficulty digesting food and emptying the stomach.
6. Functional dyspepsia: A chronic disorder characterized by symptoms such as pain, bloating, and fullness in the upper abdomen, without any identifiable cause.
7. Eosinophilic esophagitis: A condition where eosinophils, a type of white blood cell, accumulate in the esophagus, causing inflammation and difficulty swallowing.
8. Stomal stenosis: Narrowing of the opening between the stomach and small intestine, often caused by scar tissue or surgical complications.
9. Hiatal hernia: A condition where a portion of the stomach protrudes through the diaphragm into the chest cavity, causing symptoms such as heartburn and difficulty swallowing.

These are just a few examples of stomach diseases, and there are many other conditions that can affect the stomach. Proper diagnosis and treatment are essential for managing these conditions and preventing complications.

Diagnostic techniques for the digestive system are medical tests and procedures used to diagnose and evaluate various conditions and diseases related to the gastrointestinal (GI) tract, including the esophagus, stomach, small intestine, large intestine, liver, gallbladder, pancreas, and associated organs. These techniques can be categorized into invasive and non-invasive methods.

Non-invasive diagnostic techniques:

1. Imaging tests: These include X-rays, computed tomography (CT) scans, magnetic resonance imaging (MRI), positron emission tomography (PET) scans, and ultrasounds. They help visualize the structure and function of the digestive organs without requiring any invasive procedures.
2. Laboratory tests: Blood, stool, and urine samples can be analyzed to detect signs of infection, inflammation, or other abnormalities related to digestive system disorders. Examples include complete blood count (CBC), liver function tests (LFTs), coagulation studies, and fecal occult blood test (FOBT).
3. Breath tests: These are used to diagnose conditions like lactose intolerance, small intestinal bacterial overgrowth (SIBO), or helicobacter pylori infection by analyzing the patient's exhaled air after consuming a specific substance.

Invasive diagnostic techniques:

1. Endoscopy: A thin, flexible tube with a light and camera attached to its end is inserted through the mouth or rectum to directly visualize the GI tract's inner lining. There are different types of endoscopies, such as gastroscopy (esophagus, stomach, and duodenum), colonoscopy (colon and rectum), sigmoidoscopy (lower part of the colon), and enteroscopy (small intestine).
2. Endoscopic ultrasound (EUS): This combines endoscopy with ultrasound technology to provide detailed images of the digestive organs' structure and surrounding tissues, allowing for accurate diagnosis and staging of conditions like cancer.
3. Biopsy: During an endoscopy or surgery, a small tissue sample can be taken from the affected area for further examination under a microscope to confirm a diagnosis or assess the severity of a condition.
4. Capsule endoscopy: A patient swallows a tiny camera-equipped capsule that transmits images as it passes through the GI tract, allowing doctors to diagnose conditions in the small intestine that may be difficult to reach with traditional endoscopes.
5. Imaging studies: Procedures like computed tomography (CT), magnetic resonance imaging (MRI), or positron emission tomography (PET) scans can provide detailed images of the digestive organs and help diagnose conditions like tumors, inflammation, or obstructions.

These diagnostic techniques help healthcare providers identify and manage various gastrointestinal conditions, ensuring appropriate treatment and improved patient outcomes.

The pylorus is the lower, narrow part of the stomach that connects to the first part of the small intestine (duodenum). It consists of the pyloric canal, which is a short muscular tube, and the pyloric sphincter, a circular muscle that controls the passage of food from the stomach into the duodenum. The pylorus regulates the entry of chyme (partially digested food) into the small intestine by adjusting the size and frequency of the muscular contractions that push the chyme through the pyloric sphincter. This process helps in further digestion and absorption of nutrients in the small intestine.

Vomiting is defined in medical terms as the forceful expulsion of stomach contents through the mouth. It is a violent, involuntary act that is usually accompanied by strong contractions of the abdominal muscles and retching. The body's vomiting reflex is typically triggered when the brain receives signals from the digestive system that something is amiss.

There are many potential causes of vomiting, including gastrointestinal infections, food poisoning, motion sickness, pregnancy, alcohol consumption, and certain medications or medical conditions. In some cases, vomiting can be a symptom of a more serious underlying condition, such as a brain injury, concussion, or chemical imbalance in the body.

Vomiting is generally not considered a serious medical emergency on its own, but it can lead to dehydration and other complications if left untreated. If vomiting persists for an extended period of time, or if it is accompanied by other concerning symptoms such as severe abdominal pain, fever, or difficulty breathing, it is important to seek medical attention promptly.

Metoclopramide is a medication that is primarily used to manage gastrointestinal disorders. It is classified as a dopamine antagonist and a prokinetic agent, which means it works by blocking the action of dopamine, a chemical in the brain that can slow down stomach and intestine function.

The medical definition of Metoclopramide is:
A synthetic congener of procainamide, used as an antiemetic and to increase gastrointestinal motility. It has a antidopaminergic action, binding to D2 receptors in the chemoreceptor trigger zone and stomach, and it may also block 5HT3 receptors at intrapyloric and central levels. Its actions on the gut smooth muscle are mediated via cholinergic muscarinic receptors. (Source: Dorland's Medical Dictionary)

Metoclopramide is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), gastritis, and gastroparesis, which is a condition that affects the normal movement of food through the digestive tract. It can also be used to prevent nausea and vomiting caused by chemotherapy or radiation therapy.

Like any medication, Metoclopramide can have side effects, including drowsiness, restlessness, and muscle spasms. In some cases, it may cause more serious side effects such as tardive dyskinesia, a condition characterized by involuntary movements of the face, tongue, or limbs. It is important to use Metoclopramide only under the supervision of a healthcare provider and to follow their instructions carefully.

The abdominal cavity is the portion of the abdominothoracic cavity that lies between the diaphragm and the pelvic inlet. It contains the stomach, small intestine, colon, liver, pancreas, spleen, kidneys, adrenal glands, and associated blood vessels and nerves. The abdominal cavity is enclosed by the abdominal wall, which consists of muscles, fascia, and skin. It is divided into several compartments by various membranes, including the peritoneum, a serous membrane that lines the walls of the cavity and covers many of the organs within it. The abdominal cavity provides protection and support for the organs it contains, and also serves as a site for the absorption and digestion of food.

Motilin is a hormone that is produced and released by specialized cells called endocrine cells, which are located in the duodenum, which is the first part of the small intestine. Motilin plays an important role in regulating the movements of the gastrointestinal (GI) tract, also known as peristalsis.

Motilin stimulates the contraction of the smooth muscle in the GI tract, which helps to move food and other contents through the digestive system. It is particularly important for initiating the "housekeeper" wave, also known as the migrating motor complex (MMC), which occurs during periods of fasting and helps to clear out any remaining undigested material from the stomach and small intestine.

Motilin has been studied as a potential target for the treatment of gastroparesis, a condition in which the stomach is unable to empty properly due to weak or abnormal contractions of the smooth muscle. Motilin agonists, which are drugs that bind to and activate motilin receptors, have been shown to improve gastric emptying in some people with gastroparesis.

Gastroparesis without a known cause is called idiopathic gastroparesis. (nih.gov)
Many people have what is called idiopathic gastroparesis, meaning the cause is unknown and cannot be found even after medical tests. (healthyplace.com)
In about half of people with gastroparesis, the disease doesn't have a clear cause (idiopathic gastroparesis). (henryford.com)
I was diagnosed with Idiopathic Gastroparesis 19 years ago although I had displayed symptoms many years prior to the official diagnosis. (gpawarenessfund.com)
Unfortunately it did not stop the progression and long term complications with my Idiopathic Gastroparesis and severe central nervous system damage. (gpawarenessfund.com)
It seems that a large number of those with idiopathic gastroparesis, myself included, had some type of viral illness right before it happened. (yourgijourney.com)

The most common symptoms of Gastroparesis are abdominal pain, most of the time in the upper part of the abdomen, nausea, and vomiting. (minoritynurse.com)
Nausea - Eating or drinking may make individuals with gastroparesis feel nauseated. (templehealth.org)
Heartburn , nausea, weight loss, abdominal bloating, stomach muscle spasms, and vomiting undigested food are all common problems associated with diabetic gastroparesis. (doctorshealthpress.com)
The common symptoms of gastroparesis are nausea, vomiting, acid reflux, the inability to eat normal quantities of food and abdominal pain. (medgadget.com)
These symptoms patients may discuss with us are the constant presence of nausea and/or gastroparesis or a problem with their stomach's ability to empty itself of food. (caringmedical.com)
While many readers may not be familiar with the term gastroparesis, they are familiar with the symptoms they suffer from heartburn, vomiting, the sensation of being bloated, a constantly full stomach, and of course nausea. (caringmedical.com)
Symptoms of Gastroparesis include nausea, vomiting, feeling full quickly, abdominal pain and bloating, heartburn and GERD (gastroesophageal reflux disease), and early satiety (feeling full soon after beginning to eat). (ayushakti.com)
As symptoms include vomiting, nausea, abdominal pain and feeling full after a few mouthfuls, this can unfortunately lead to (sometimes dangerous) weight loss and at times, those with gastroparesis may need to be tube-fed. (gutscharity.org.uk)
Gastroparesis results when there is some damage or malfunction to this process in the stomach, resulting in symptoms such as nausea and vomiting, severe abdominal pain, bacterial infections and weight loss. (rnexltd.ie)
But my nausea and vomitting didn't go away and after many years of Dr's trying to figure out what was wrong I was told I had Gastroparesis. (aboutgastroparesis.org)
BackgroundChronic gastroduodenal disorders including, chronic nausea and vomiting syndrome, gastroparesis, and functional dyspepsia, are challenging to diagnose and manage. (curegp.org)

Gastroparesis occurs when the nerves to the stomach are damaged or don't work. (answers.com)
Gastroparesis, also called delayed gastric emptying, is a disorder in which the stomach takes too long to empty its contents. (healthyplace.com)
Gastroparesis occurs when the vagus nerve is damaged and the muscles of the stomach and intestines do not work normally. (healthyplace.com)
Since gastroparesis makes stomach emptying unpredictable, a person's blood glucose levels can be erratic and difficult to control. (healthyplace.com)
Gastroparesis is likely if the x ray shows food in the stomach. (healthyplace.com)
Gastroparesis is a stomach disorder. (childrensnational.org)
Gastroparesis is a diagnosis that refers to abnormal stomach movement with slow emptying of the stomach," says Mackenzie McArthur MPAM, DMSc, PA-C, instructor in the department of Internal Medicine, Director of Neurogenic Bowel Program, Atrium Health Gastroenterology and Hepatology . (minoritynurse.com)
Gastroparesis, or delayed gastric emptying, occurs when food doesn't move from your stomach to your small intestine as it should. (henryford.com)
But with gastroparesis, nerve damage or muscle weakness in the stomach disrupts digestion. (henryford.com)
This publication addresses commonly asked questions about gastroparesis, a condition where symptoms occur and the stomach empties too slowly. (iffgd.org)
Gastroparesis is a motility disorder of the stomach, where there is a delay in the stomach's ability to empty into the small intestine. (chop.edu)
Gastroparesis is a disorder involving your stomach muscles. (barnesjewish.org)
Gastroparesis is the medical term for delayed stomach emptying. (gicare.com)
For patients with gastroparesis, fatty foods and oils should be restricted, because they delay stomach emptying. (gicare.com)
A six-year, $13.5 million study of the vagus nerve's connection from the brain to the stomach has ignited interest from Indiana gastroenterologists and their hundreds of patients suffering from gastroparesis, a health condition where the stomach does not empty appropriately. (purdue.edu)
The vagus nerve involuntarily stimulates muscles of the stomach to contract for normal stomach emptying, and more information about how it functions will be helpful in identifying treatments for health conditions like gastroparesis. (purdue.edu)
Diabetic gastroparesis is a medical phrase used to describe an uncomfortable condition in which the stomach takes too long to empty its contents. (doctorshealthpress.com)
Gastroparesis is a condition where the stomach is unable to push food through the digestive tract after it gets digested. (medgadget.com)
For people with gastroparesis, the muscles in the stomach are unable to empty the stomach or take a very long time to empty the contents. (medgadget.com)
When someone has gastroparesis, the stomach muscles don't work as they should and cause a delay in this emptying process. (frankfortregional.com)
Gastroparesis is most common in people who have diabetes or had previous surgery on their esophagus, stomach or small intestine. (frankfortregional.com)
Radiation treatments for cancer targeting the chest or stomach may also cause gastroparesis. (frankfortregional.com)
Gastroparesis causes your stomach to empty much more slowly than it should. (lathamcenters.org)
Changing your child's diet can aid the stomach to empty faster and avoid further episodes of gastroparesis. (lathamcenters.org)
A condition that affects the stomach muscles is called Gastroparesis. (ayushakti.com)
Gastroparesis is a condition in which the stomach muscles are unable to contract properly, causing the stomach to empty its contents more slowly. (ayushakti.com)
Gastroparesis is the poor breakdown of food in the stomach. (ayushakti.com)
For Gastroparesis, people who take Ayurvedic natural remedies may be able to improve how the stomach works and avoid the symptoms that come from the stomach not emptying completely. (ayushakti.com)
In patients with Gastroparesis, the damaged vagus nerve prevents the stomach muscles from working properly and prevents the muscles from moving spontaneously (motility). (ayushakti.com)
The damage to the vagus nerve that leads to Gastroparesis can be brought on by certain diseases like diabetes or a procedure involving the stomach or small intestine during surgery. (ayushakti.com)
Many health issues, such as severe dehydration, hardening of undigested food that remains in the stomach, and frequent changes in blood sugar levels, can result from Gastroparesis. (ayushakti.com)
Gastroparesis literally translates to paralysis of the stomach . (gutscharity.org.uk)
Gastroparesis is a chronic (long lasting) disorder where the stomach does not empty the contents in a normal way. (gutscharity.org.uk)
There, I was finally diagnosed with gastroparesis, which means my stomach is paralysed. (gutscharity.org.uk)
A medical term that indicates a paralyzed stomach, gastroparesis is one of the more concerning and severe digestive motility conditions. (dhat.com)
Medications: Opioid pain relievers, some antidepressants, allergy medications, and high blood pressure medications may cause impaired stomach clearing and lead to gastroparesis-like symptoms. (dhat.com)
My Gastroparesis was found after completing a Gastric Emptying study-GES which showed my stomach was emptying food at a rate of less than 2 percent. (gpawarenessfund.com)
Gastroparesis is a gastrointestinal disorder characterized by delayed stomach emptying unrelated to a physical blockage. (100answers.com)
Gastroparesis is a stomach disorder in which stomach muscles don't contract properly, leading to problems crushing food before digestion… What is gastroparesis? (familydoctor.org)
Other causes of gastroparesis include surgery on the stomach or vagus nerve, viral infections, anorexia nervosa or bulimia, certain medications, gastroesophageal reflux disease, smooth muscle disorders, nervous system disorders, and metabolic disorders. (medassociatesmiddletown.com)
Gastroparesis is a condition when your stomach is slow to empty food into your intestine and causes bloating after you eat. (cedarvalleygi.com)

Can anti-depressants cause gastroparesis? (answers.com)
These medicines do not cause gastroparesis. (nih.gov)
What factors cause gastroparesis? (dhat.com)

Gastroparesis present similar symptoms to slow gastric emptying caused by certain opioid medications, antidepressants, and allergy medications, along with high blood pressure. (wikipedia.org)
Certain medicines may delay gastric emptying or affect motility , resulting in symptoms that are similar to those of gastroparesis. (nih.gov)
Because a person with gastroparesis can sometimes have normal emptying, the doctor may repeat the test another day if gastroparesis is suspected. (healthyplace.com)
Once other causes have been ruled out, the doctor will perform one of the following gastric emptying tests to confirm a diagnosis of gastroparesis. (healthyplace.com)
If delayed emptying is noted, there is a positive diagnosis of gastroparesis. (minoritynurse.com)
In another clinical trial, researchers investigated the effects of electroacupuncture on gastric emptying time and blood glucose levels in 19 diabetic patients with gastroparesis. (doctorshealthpress.com)
August is Gastroparesis Awareness Month, and a good time to learn more about this digestive disorder that's also known as delayed gastric emptying. (frankfortregional.com)
We present the results of a double blind, placebo controlled, crossover study of ghrelin in gastric emptying in patients with diabetic gastroparesis. (bmj.com)
Ghrelin increases gastric emptying in patients with diabetic gastroparesis. (bmj.com)
Background: Gastroparesis is a digestive syndrome characterized by delayed gastric emptying (GE) and by symptoms that are suggestive of gastroduodenal motor disorders. (unibo.it)

Many people with gastroparesis experience a wide range of symptoms, and sometimes the disorder is difficult for the physician to diagnose. (healthyplace.com)
People with gastroparesis who experience vomiting may throw up bits or even whole pieces of undigested food. (100answers.com)
People with gastroparesis often report finding it difficult to participate in social situations due to their dietary restrictions and eating activities. (mindovergut.com)

The vagus nerve becomes damaged by years of high blood glucose or insufficient transport of glucose into cells resulting in gastroparesis. (wikipedia.org)
Chronic gastroparesis can be caused by other types of damage to the vagus nerve, such as abdominal surgery. (wikipedia.org)
Gastroparesis is caused when the vagus nerve is damaged or stops working. (childrensnational.org)
Electrode and stimulator development for gastroparesis was encouraged by electrode treatment on the vagus nerve for patients with drug-resistant epilepsy. (purdue.edu)
Just how much stimulation to the vagus nerve is needed to treat gastroparesis depends on the patient. (purdue.edu)
Gastroparesis is usually caused by damage to the vagus nerve. (doctorshealthpress.com)
Diabetics often suffer from gastroparesis because high blood glucose levels can damage the vagus nerve over time. (doctorshealthpress.com)
Damage to the "vagus" nerve has been linked to Gastroparesis. (ayushakti.com)
Gastroparesis is the result of damage to the vagus nerve, which controls the movement of food through the digestive system. (medassociatesmiddletown.com)
Damage to the vagus nerve is another cause of gastroparesis. (yourgijourney.com)
Incidentally, the sugar imbalances that lead to diabetic gastroparesis do so through damage to the vagus nerve. (yourgijourney.com)

One recent trial compared the effectiveness of domperidone (a common medication used to treat gastroparesis) and acupuncture for the treatment of diabetic gastroparesis. (doctorshealthpress.com)
What is the best way to treat Gastroparesis? (ayushakti.com)
Several medications are used to treat gastroparesis. (medassociatesmiddletown.com)

Since 2016, August has marked Gastroparesis Awareness Month to raise an understanding and highlight education about this disorder. (minoritynurse.com)
As of July 1, 2015: The Gastroparesis Awareness Campaign has reached out to over 8 million strong by raising national attention to this rare GI disorder and providing Gastroparesis awareness programs all around the world. (gpawarenessfund.com)
Gastroparesis is a neuromuscular disorder of the upper gastrointestinal tract. (curegp.org)

In fact, diabetes mellitus has been named as the most common cause of gastroparesis, as high levels of blood glucose may effect chemical changes in the nerves. (wikipedia.org)
The most common cause of gastroparesis is diabetes. (healthyplace.com)

Conversely, acupuncture treatments resulted in a decrease in all symptoms associated with gastroparesis as well as improving overall quality of life scores. (doctorshealthpress.com)
The research team concluded that short term electro acupuncture reduces symptoms associated with gastroparesis . (doctorshealthpress.com)
Here's a look at the main symptoms associated with gastroparesis. (100answers.com)

Sponsored by the International Foundation for Gastrointestinal Disorders (IFFGD) , Gastroparesis Awareness Month can help all nurses identify patients who might be misdiagnosed. (minoritynurse.com)
August is gastroparesis awareness month. (gutscharity.org.uk)
Given that August is Gastroparesis Awareness Month, we have provided detailed information below about the condition to help educate patients on the condition. (dhat.com)
Another Gastroparesis Awareness Month proclamation! (curegp.org)
Not exactly what I wish to hear at the close of Gastroparesis Awareness Month: 'We note a scarcity of new compounds for the treatment of GP. (curegp.org)
To end Gastroparesis Awareness Month on a positive note, we decided to draw one last 'Grand Prize' winner from our contest entries. (curegp.org)

Slow, heavy digestion" is a characteristic of Gastroparesis. (ayushakti.com)
According to the classic texts, the aggravation of one or more of the body's three doshas-Vata, Pitta, or Kapha-causes a "slow digestion" condition like Gastroparesis. (ayushakti.com)
Gastric neurostimulation for gastroparesis: time to pick up the pace1 1Gastric electrical stimulation in intractable symptomatic gastroparesis.Digestion 2002;66:204-212. (mcmaster.ca)
Because gastroparesis affects peristalsis (the involuntary, wave-like muscle contractions that drive typical human digestion), food may become caught in the digestive system. (100answers.com)

Causes, symptoms, treatment of diabetes-related gastroparesis. (healthyplace.com)

Gastroparesis affects how well the digestive system works. (frankfortregional.com)
If you have symptoms of gastroparesis, there are advanced diagnostic tests to determine how well your digestive system is working. (frankfortregional.com)
1]] A digestive system affected by gastroparesis fails to contract normally. (100answers.com)

Depending on the severity of the condition, gastroparesis treatment options vary. (medgadget.com)
Gastroparesis severity was associated with small bowel motor abnormalities but not with delayed GE. (unibo.it)
Treatment of gastroparesis depends on the severity of the symptoms. (medassociatesmiddletown.com)
The severity of the condition may be different for those with diabetic gastroparesis. (yourgijourney.com)

In most cases, gastroparesis is a long-term (chronic) condition. (childrensnational.org)
In most cases, treatment does not cure gastroparesis, which is usually a chronic condition. (medassociatesmiddletown.com)
If you suffer from gastroparesis or other chronic GI disorders, it can be easy to feel alone. (curegp.org)
Another, albeit uncommon, possibility is for gastroparesis to be the result of another chronic condition that has already been diagnosed (other than diabetes). (yourgijourney.com)
Alongside the challenges of managing chronic gastrointestinal symptoms, research shows that some other factors may also influence distress levels in individuals living with gastroparesis. (mindovergut.com)

Vomiting - Regular vomiting after meals, including vomiting undigested food, may be a sign of gastroparesis. (templehealth.org)
Malnutrition could be a sign of gastroparesis for several reasons. (100answers.com)

Patients with cancer may develop gastroparesis because of chemotherapy-induced neuropathy, immunosuppression followed by viral infections involving the GI tract, procedures such as celiac blocks, paraneoplastic neuropathy or myopathy, or after an allogeneic bone marrow transplant via graft-versus-host disease. (wikipedia.org)

Treatment will not cure gastroparesis, but it can help you manage the disease. (childrensnational.org)

If you have severe gastroparesis, we offer a range of gastroparesis surgeries at our Center for Motility Disorders, focusing on two advanced procedures: gastric neurostimulator surgery and gastric peroral endoscopic myotomy. (henryford.com)
Patients with and without delayed GE showed similar moderate/severe gastroparesis manifestations, but patients with ED significantly more often had moderate/severe gastroparesis manifestations than patients with normal SBM (grade 1:14% vs 39%, grade 2:62% vs 56%, grade 3:24% vs 5%, respectively). (unibo.it)

Other conditions can also trigger gastroparesis. (doctorshealthpress.com)

As you can see, there are many different reasons that people might develop gastroparesis. (yourgijourney.com)

Surgical placement of a gastric stimulator has shown promising results in patients wiht refractory gastroparesis. (sages.org)

Ayurveda can provide a natural and alternative treatment option for Gastroparesis that can assist in symptom management. (ayushakti.com)
Expert recommendations for alleviating this symptom of gastroparesis include eating smaller meals, avoiding high-fiber foods, incorporating more soups and purees, avoiding carbonated drinks, and not lying down for at least 2 hours after eating. (100answers.com)

When gastroparesis occurs, however, the stomach's ability to digest and move food slows considerably or may not work at all. (dhat.com)

At its worst, gastroparesis can lead to intractable vomiting and an inability to feed, and carries a poor prognosis. (bmj.com)

What are the complications of gastroparesis? (healthyplace.com)

Overall survival in gastroparesis patients is significantly lower than survival in the general population. (wikipedia.org)
For patients already with gastroparesis, these can make the condition worse. (wikipedia.org)
Nurses can be watchful for digestive troubles and, says McArthur, of the some patients who could have conditions that make gastroparesis more common. (minoritynurse.com)
Patients will also likely work with a healthcare team that might include a gastrointestinal registered dietician for the gastroparesis type diet which could be very different from the patient's current diet. (minoritynurse.com)
Nurses can help patients with gastroparesis and/or motility conditions by showing compassion and empathy," says McArthur. (minoritynurse.com)
Six type 1 diabetic patients with a previous scintigraphic demonstration of gastroparesis and five healthy subjects were recruited for the study. (nih.gov)
Erythromycin may represent an effective therapeutic alternative to more established forms of treatment in patients with diabetic gastroparesis, especially when other drugs have failed. (nih.gov)
For example, diabetes patients with gastroparesis are allowed sugar-containing liquids on the Step 1 diet, because that is their only source of carbohydrate. (gicare.com)
Powley collaborated with IU School of Medicine gastrointestinal doctors in gathering data on gastroparesis patients and a healthy population. (purdue.edu)
Patients diagnosed with both diabetes and gastroparesis were recruited for the study. (doctorshealthpress.com)
A single-blinded, randomized pilot study evaluating effects of electroacupuncture in diabetic patients with symptoms suggestive of gastroparesis," J Altern Complement Med . (doctorshealthpress.com)
The rise in the number of gastroparesis patients all over the world has created a demand for quality treatment process. (medgadget.com)
Ten insulin requiring diabetic patients (five men, six type I) referred with symptoms indicative of gastroparesis received a two hour infusion of either ghrelin (5 pmol/kg/min) or saline on two occasions. (bmj.com)
Ayurvedic practitioners advise Gastroparesis patients to avoid foods that aggravate the associated dosha. (ayushakti.com)
In addition, patients with Gastroparesis should drink a lot of water and consume food that has been thoroughly cooked and pureed and easy to digest. (ayushakti.com)
Many patients who have gastroparesis might not experience noticeable symptoms. (dhat.com)
There is nothing more gratifying in life than knowing you will leave a legacy behind when Heaven calls helping millions of other Gastroparesis patients on their own personal journey. (gpawarenessfund.com)
In October 2005, I started the 'Gastroparesis Awareness Campaign Organization' working with other Gastroparesis patients, family members, loved ones, medical professionals, bio-tech companies and International government to help shed light on much needed medical research and public Gastroparesis awareness. (gpawarenessfund.com)
Reflux in gastroparesis patients may occur more often with fiber-rich or fatty foods that are more difficult to digest. (100answers.com)
One study found that as many as 90% of gastroparesis patients reported pain in the upper or mid-center abdominal regions. (100answers.com)
Gastroparesis patients often experience early satiety, meaning they tend to feel full quickly when eating. (100answers.com)
Interestingly, studies show that patients with gastroparesis can also gain weight as a result of the condition. (100answers.com)
It's also possible for gastroparesis patients to become malnourished due to dietary changes made to avoid other gastroparesis symptoms, such as pain and bloating. (100answers.com)
There is a lack of evidence-based information about what drugs work best for patients with gastroparesis. (aboutgastroparesis.org)
Aim: To investigate enteric dysmotility (ED) in patients with suspected gastroparesis. (unibo.it)
Methods: Patients with symptoms suggestive of gastroparesis were consecutively included in the study and underwent a 13 C-octanoic acid GE breath test and small bowel manometry (SBM). (unibo.it)
Conclusions and Inferences: Enteric dysmotility was more frequent than delayed GE in patients with symptoms suggestive of gastroparesis. (unibo.it)
The use of botulism toxin has been associated with improvement in symptoms of gastroparesis in some patients. (medassociatesmiddletown.com)
Emergency department visits among diabetic gastroparesis patients have doubled in less than a decade. (gimotirxhcp.com)

He is among a packed roster of researchers, anatomists and physicians from Purdue and far beyond West Lafayette who have experimented with electrode and stimulator surgical implants on the stomachs of those suffering from gastroparesis. (purdue.edu)
Gastroparesis treatment is opted by both hospitals and ambulatory surgical centers. (medgadget.com)

Gastroparesis may improve with the right combination of nonsurgical therapies and changes to your diet and lifestyle. (henryford.com)
The purpose of the gastroparesis diet is to reduce symptoms and maintain adequate fluids and nutrition. (gicare.com)
The STEP 1 Gastroparesis Diet is inadequate in all nutrients except sodium and potassium. (gicare.com)

The experts at our Center for Motility Disorders offer advanced procedures for gastroparesis, including gastric neurostimulators and G-POEM procedures, an endoscopic treatment performed entirely through your mouth. (henryford.com)
Gastroparesis may be caused by various conditions such as diabetes mellitus, certain disorders of the nervous system, or certain drugs. (gicare.com)
Understanding nerves' interactions with organs can better control and regulate function in those suffering from diabetes, hypertension and gastrointestinal disorders like gastroparesis. (purdue.edu)
Some people with disorders that affect multiple parts of the body are simply more prone to the development of gastroparesis. (yourgijourney.com)
Ehrlos-Danlos Syndrome and Mitochondrial Disorders are two rare disorders that can sometimes produce gastroparesis. (yourgijourney.com)

W e already talked about what gastroparesis is and how it disrupts the motility of the GI tract. (yourgijourney.com)

One of the main symptoms of gastroparesis is a feeling of fullness that occurs quickly after the individual starts eating. (100answers.com)

Though the diagnosis is somewhat rare, symptoms similar to gastroparesis occur in about 1 out of every 4 adults in the U.S. (frankfortregional.com)

Gastroparesis affects one out of 25 Americans, including kids. (dhat.com)

Objectives This meta-analysis aimed to systematically evaluate the efficacy of acupuncture in treating postsurgical gastroparesis syndrome (PGS) after thoracic or abdominal surgery. (bmj.com)

Get gastroparesis treatment from Michigan's top digestive disease specialists at Henry Ford Health. (henryford.com)
They found that there were no changes in blood glucose or symptoms of gastroparesis in the domperidone treatment group. (doctorshealthpress.com)
Gastroparesis treatment includes medications to help the muscles function properly or possible surgery to rectify the condition. (medgadget.com)
This global gastroparesis treatment market study talks about the past and the present conditions of this industry and forecasts how the growth of the same would be between the years 2019 and 2025. (medgadget.com)
Diabetic gastroparesis is a disabling condition with no consistently effective treatment. (bmj.com)
5 One possible explanation for this lack of sustained response to treatment is that gastroparesis may be aetiologically associated with progressive autonomic neuropathy. (bmj.com)
This project has provided some promising initial findings that stem cell-based treatments could be a future treatment for conditions like achalasia and gastroparesis. (gutscharity.org.uk)
The experienced gastrointestinal (GI) specialists at Digestive Health Associates of Texas provide treatment for gastroparesis. (dhat.com)
Gastric pacing as a treatment for intractable gastroparesis: Shocking news? (mcmaster.ca)
Levitra is a prescription medication for the treatment of erectile dysfunction (ED). Cialis farmacie online erythromycin ethylsuccinate gastroparesis . (onlinehome.us)
Only one drug, metoclopramide, is approved by the U.S. Food and Drug Administration (FDA) for the treatment of gastroparesis. (aboutgastroparesis.org)
Pharmacologic treatment of gastroparesis: What is (still) on the horizon? (curegp.org)
Gumaste V, Baum J: Treatment of gastroparesis: An update. (msdmanuals.com)

Opioids and anticholinergic medications can cause medication-induced gastroparesis. (wikipedia.org)
For my gastroparesis, I was prescribed medications for constipation. (caringmedical.com)
Medications are used to try to help reduce symptoms of gastroparesis. (aboutgastroparesis.org)
Indications & Dosage erythromycin iv dose for gastroparesis .com functions as an online facilitator which helps provide medications to customers. (onlinehome.us)

If you have gastroparesis, you may feel full long after eating a meal. (nih.gov)
2]] While a healthy person may be able to eat a three-course meal before satiating hunger, someone with gastroparesis may only be able to consume an appetizer before being too uncomfortable to continue. (100answers.com)

The symptoms of gastroparesis may be mild or severe, depending on the person. (healthyplace.com)
This is because the degree of gastroparesis may range from severe and long-standing to mild and easily corrected. (gicare.com)

If he is successful, we might be able to treat achalasia and diabetic gastroparesis in the future by injecting new nerve cells into the relevant part of the gut, to restore its function. (gutscharity.org.uk)

Such fluctuations in blood sugar worsen diabetes, which could also worsen gastroparesis. (dhat.com)
Research shows that individuals living with gastroparesis tend to report lower quality of life than the general population, and that psychological distress tends to increase as gastroparesis symptoms worsen. (mindovergut.com)

I refuse to allow anyone with Gastroparesis to suffer alone or in silence. (gpawarenessfund.com)

The total prevalent population of gastroparesis worldwide is expected to increase from 33.7 million persons in 2017 to 36.2 million persons in 2030. (rnexltd.ie)

I was wondering if anyone else was put on Metoclopramide for Gastroparesis. (mayoclinic.org)
Gimoti ® (metoclopramide) nasal spray is indicated for the relief of symptoms in adults with acute and recurrent diabetic gastroparesis. (gimotirxhcp.com)

Transient gastroparesis may arise in acute illness of any kind, as a consequence of certain cancer treatments or other drugs which affect digestive action, or due to abnormal eating patterns. (wikipedia.org)
Countries and regions like North America, Europe, and Asia-Pacific lead the market when it comes to opting for gastroparesis treatments . (medgadget.com)

Erythromycin, a macrolide antibiotic, has been shown to have gastric prokinetic effects and has been proposed as an alternative therapeutic option for diabetic gastroparesis. (nih.gov)
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Anatomy4

Diseases6

Chemicals and Drugs5

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes2

Natural history of diabetic gastroparesis. (1/173)

Gastric emptying rate assessment based on the proportion of intra-abdominal radioactivity in the stomach. (2/173)

Measurement of gastric emptying by standardized real-time ultrasonography in healthy subjects and diabetic patients. (3/173)

Evaluation and management of dyspepsia. (4/173)

Comparative effects of levosulpiride and cisapride on gastric emptying and symptoms in patients with functional dyspepsia and gastroparesis. (5/173)

Effects of fedotozine on gastric emptying and upper gastrointestinal symptoms in diabetic gastroparesis. (6/173)

Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis. (7/173)

Gastroparesis following bone marrow transplantation. (8/173)

Gastroparesis

Gastric Emptying

Interstitial Cells of Cajal

Gastrointestinal Agents

Cisapride

Stomach

Diabetic Neuropathies

Anti-Dyskinesia Agents

Electric Stimulation Therapy

Gastroenterostomy

Gastric Dilatation

Gastrointestinal Motility

Diabetes Complications

Stomach Diseases

Diagnostic Techniques, Digestive System

Pylorus

Vomiting

Metoclopramide

Abdominal Cavity

Motilin

Natural history of diabetic gastroparesis. (1/173)

Gastric emptying rate assessment based on the proportion of intra-abdominal radioactivity in the stomach. (2/173)

Measurement of gastric emptying by standardized real-time ultrasonography in healthy subjects and diabetic patients. (3/173)

Evaluation and management of dyspepsia. (4/173)

Comparative effects of levosulpiride and cisapride on gastric emptying and symptoms in patients with functional dyspepsia and gastroparesis. (5/173)

Effects of fedotozine on gastric emptying and upper gastrointestinal symptoms in diabetic gastroparesis. (6/173)

Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis. (7/173)

Gastroparesis following bone marrow transplantation. (8/173)

Idiopathic gastroparesis6

Nausea11

Stomach41

Cause gastroparesis3

Emptying10

People with gastroparesis3

Vagus11

Treat gastroparesis3

Disorder3

Common cause of gastroparesis2

Symptoms associated with gastroparesis3

Awareness Month6

Digestion4

Diabetes-related gastroparesis1

Digestive system3

Severity4

Chronic5

Sign of gastroparesis2

Viral1

Cure gastroparesis1

Severe gastroparesis2

Trigger gastroparesis1

Develop gastroparesis1

Refractory gastroparesis1

Symptom2

Stomach's ability1

Vomiting1

Complications1

Patients29

Surgical2

Diet3

Disorders5

Motility1

Occurs1

Diagnosis1

Affects1

Abdominal1

Treatment13

Medications4

Meal2

Mild2

Nerve1

Worsen2

Suffer1

20171

Metoclopramide2

Treatments2

Erythromycin13