Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
An acute or chronic GINGIVITIS characterized by redness and swelling, NECROSIS extending from the interdental papillae along the gingival margins, PAIN; HEMORRHAGE, necrotic odor, and often a pseudomembrane. The condition may extend to the ORAL MUCOSA; TONGUE; PALATE; or PHARYNX. The etiology is somewhat unclear, but may involve a complex of FUSOBACTERIUM NUCLEATUM along with spirochetes BORRELIA or TREPONEMA.
A fulminating bacterial infection of the deep layers of the skin and FASCIA. It can be caused by many different organisms, with STREPTOCOCCUS PYOGENES being the most common.
ENTEROCOLITIS with extensive ulceration (ULCER) and NECROSIS. It is observed primarily in LOW BIRTH WEIGHT INFANT.
A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
A severe form of acute INFLAMMATION of the PANCREAS characterized by one or more areas of NECROSIS in the pancreas with varying degree of involvement of the surrounding tissues or organ systems. Massive pancreatic necrosis may lead to DIABETES MELLITUS, and malabsorption.
An index which scores the degree of dental plaque accumulation.
A numerical rating scale for classifying the periodontal status of a person or population with a single figure which takes into consideration prevalence as well as severity of the condition. It is based upon probe measurement of periodontal pockets and on gingival tissue status.
The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY.
A fluid occurring in minute amounts in the gingival crevice, believed by some authorities to be an inflammatory exudate and by others to cleanse material from the crevice, containing sticky plasma proteins which improve adhesions of the epithelial attachment, have antimicrobial properties, and exert antibody activity. (From Jablonski, Illustrated Dictionary of Dentistry, 1982)
Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
A severe gangrenous process occurring predominantly in debilitated and malnourished children, especially in underdeveloped countries. It typically begins as a small vesicle or ulcer on the gingiva that rapidly becomes necrotic and spreads to produce extensive destruction of the buccal and labial mucosa and tissues of the face, which may result in severe disfigurement and even death. Various bacteria have been implicated in the etiology. (Dorland, 27th ed)
Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed)
Oral tissue surrounding and attached to TEETH.
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.
Dentifrices that are formulated into a paste form. They typically contain abrasives, HUMECTANTS; DETERGENTS; FLAVORING AGENTS; and CARIOSTATIC AGENTS.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium is a common commensal in the gingival crevice and is often isolated from cases of gingivitis and other purulent lesions related to the mouth.
Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
Abnormal concretion or calcified deposit that forms around the teeth or dental prostheses.
A combination of the debris index and the dental calculus index to determine the status of oral hygiene.
An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.
Any preparations used for cleansing teeth; they usually contain an abrasive, detergent, binder and flavoring agent and may exist in the form of liquid, paste or powder; may also contain medicaments and caries preventives.
A benign, inflammatory, variably ulcerated, occasionally bilateral, self-healing lesion of the minor salivary glands that is often confused clinically and histologically with carcinoma.
A family of gram-negative bacteria found primarily in the intestinal tracts and mucous membranes of warm-blooded animals. Its organisms are sometimes pathogenic.
The practice of personal hygiene of the mouth. It includes the maintenance of oral cleanliness, tissue tone, and general preservation of oral health.
Infections with bacteria of the genus TREPONEMA.
A genus of gram-negative, anaerobic, rod-shaped bacteria found in cavities of humans and other animals. No endospores are formed. Some species are pathogenic and occur in various purulent or gangrenous infections.
A species of gram-negative bacteria in the family Prevotellaceae. It is the species most commonly isolated from endodontic infections (PULPITIS).
A species of bacteria in the family SPIROCHAETACEAE, frequently isolated from periodontal pockets (PERIODONTAL POCKET).
Devices used in the home by persons to maintain dental and periodontal health. The devices include toothbrushes, dental flosses, water irrigators, gingival stimulators, etc.
Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
A genus of gram-negative, anaerobic cocci parasitic in the mouth and in the intestinal and respiratory tracts of man and other animals.
A derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.
'Tooth diseases' is a broad term referring to various conditions affecting the teeth, including dental caries (cavities), periodontal disease (gum disease), tooth wear, tooth sensitivity, oral cancer, and developmental anomalies, which can result in pain, discomfort, or loss of teeth if left untreated.
A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5)
A genus of microorganisms of the order SPIROCHAETALES, many of which are pathogenic and parasitic for man and animals.
Development of lesions in the lymph node characterized by infiltration of the cortex or paracortex by large collections of proliferating histiocytes and complete or, more often, incomplete necrosis of lymphoid tissue.
Inflammation of the fascia. There are three major types: 1, Eosinophilic fasciitis, an inflammatory reaction with eosinophilia, producing hard thickened skin with an orange-peel configuration suggestive of scleroderma and considered by some a variant of scleroderma; 2, Necrotizing fasciitis (FASCIITIS, NECROTIZING), a serious fulminating infection (usually by a beta hemolytic streptococcus) causing extensive necrosis of superficial fascia; 3, Nodular/Pseudosarcomatous /Proliferative fasciitis, characterized by a rapid growth of fibroblasts with mononuclear inflammatory cells and proliferating capillaries in soft tissue, often the forearm; it is not malignant but is sometimes mistaken for fibrosarcoma.
The removal of foreign material and devitalized or contaminated tissue from or adjacent to a traumatic or infected lesion until surrounding healthy tissue is exposed. (Dorland, 27th ed)
The act of cleaning teeth with a brush to remove plaque and prevent tooth decay. (From Webster, 3d ed)
Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)
'Mouth diseases' is a broad term referring to various conditions that cause inflammation, infection, or structural changes in any part of the mouth, including the lips, gums, tongue, palate, cheeks, and teeth, which can lead to symptoms such as pain, discomfort, difficulty in chewing or speaking, and altered aesthetics.
Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
Inflammation of the gingiva surrounding the crown of a tooth.
A plant genus of the family ASTERACEAE. Members contain CAROTENOIDS, essential oils (OILS, VOLATILE), flavonoids, mucilage, SAPONINS, and STEROLS. The plants are used both topically and internally. The common name of Marigold is also used for TAGETES.
A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.
Removal of dental plaque and dental calculus from the surface of a tooth, from the surface of a tooth apical to the gingival margin accumulated in periodontal pockets, or from the surface coronal to the gingival margin.
'Gingival diseases' is a general term for conditions affecting the soft tissues surrounding and supporting the teeth, primarily characterized by inflammation, bleeding, redness, or swelling, which can progress to periodontal disease if left untreated.
Inorganic fluorides of tin. They include both stannic fluoride (tin tetrafluoride) and stannous fluoride (tin difluoride). The latter is used in the prevention of dental caries.
A family of spiral bacteria of the order SPIROCHAETALES.
A plant species of the Salvia genus known as a spice and medicinal plant.
The poppy plant family of the order Papaverales, subclass Magnoliidae, class Magnoliopsida. These have bisexual, regular, cup-shaped flowers with one superior pistil and many stamens; 2 or 3 conspicuous, separate sepals and a number of separate petals. The fruit is a capsule. Leaves are usually deeply cut or divided into leaflets.
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
A genus of gram-positive, rod-shaped bacteria whose organisms are nonmotile. Filaments that may be present in certain species are either straight or wavy and may have swollen or clubbed heads.
Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.
A republic in western Africa, north of NIGERIA and west of CHAD. Its capital is Niamey.
A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842)
Infections with bacteria of the family BACTEROIDACEAE.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.
"Decayed, missing and filled teeth," a routinely used statistical concept in dentistry.
'Infant, Premature, Diseases' refers to health conditions or abnormalities that specifically affect babies born before 37 weeks of gestation, often resulting from their immature organ systems and increased vulnerability due to preterm birth.
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
A procedure for smoothing of the roughened root surface or cementum of a tooth after subgingival curettage or scaling, as part of periodontal therapy.
Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.
Mushrooms in the order AGARICALES containing B vitamins, cortinelin, and the polysaccharide LENTINAN.
A group of different species of microorganisms that act together as a community.
Devices used for influencing tooth position. Orthodontic appliances may be classified as fixed or removable, active or retaining, and intraoral or extraoral. (Boucher's Clinical Dental Terminology, 4th ed, p19)
A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.
A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
Activated form of FACTOR XIII, a transglutaminase, which stabilizes the formation of the fibrin polymer (clot) culminating the blood coagulation cascade.
The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
A plant genus of the family BURSERACEAE which is a source of gugulipid and guggulu extract. Balm of Gilead is a common name more often referring to POPULUS and sometimes to ABIES.
Pneumonia caused by infections with bacteria of the genus STAPHYLOCOCCUS, usually with STAPHYLOCOCCUS AUREUS.
A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
A family of gram-negative bacteria, in the phylum FIRMICUTES.

Pathogenesis of cancrum oris (noma): confounding interactions of malnutrition with infection. (1/22)

This study showed that impoverished Nigerian children at risk for cancrum oris (noma) had significantly reduced plasma concentrations of zinc (< 10.8 micromol/L), retinol (< 1.05 micromol/L), ascorbate (< 11 micromol/L), and the essential amino acids, with prominently increased plasma and saliva levels of free cortisol, compared with their healthy counterparts. The nutrient deficiencies, in concert with previously reported widespread viral infections (measles, herpesviruses) in the children, would impair oral mucosal immunity. We postulate, subject to additional studies, that evolution of the oral mucosal ulcers including acute necrotizing gingivitis to noma is triggered by a consortium of microorganisms of which Fusobacterium necrophorum is a key component. Fusobacterium necrophorum elaborates several dermonecrotic toxic metabolites and is acquired by the impoverished children via fecal contamination resulting from shared residential facilities with animals and very poor environmental sanitation.  (+info)

Characterization of an autoantigen associated with chronic ulcerative stomatitis: the CUSP autoantigen is a member of the p53 family. (2/22)

A unique clinical syndrome has been described in which patients have chronic oral ulceration and autoantibodies to nuclei of stratified squamous epithelium. We have characterized the autoantibodies from patients sera and found that the major autoantigen is a 70 kDa epithelial nuclear protein. Sequencing of the cDNA for this protein, chronic ulcerative stomatitis protein, revealed it to be homologous to the p53 tumor suppressor and to the p73 putative tumor suppressor, and to be a splicing variant of the KET gene. The p53-like genes, p73 and the several KET splicing variants, are recently described genes of uncertain biologic and pathologic significance. This study provides the first clear association of a p53-like protein with a disease process.  (+info)

Treponema parvum sp. nov., a small, glucoronic or galacturonic acid-dependent oral spirochaete from lesions of human periodontitis and acute necrotizing ulcerative gingivitis. (3/22)

Small oral spirochaetes with a strict dependence on either glucuronic acid (GluA) or galacturonic acid (GalA) were isolated from European patients with periodontitis and from Chinese patients with either gingivitis or acute necrotizing ulcerative gingivitis (ANUG). Thirteen such isolates were similar phenotypically to Treponema pectinovorum ATCC 33768T and this classification was confirmed by 16S rRNA sequencing. However, four isolates differed from T. pectinovorum by their small cell size, by a prominent beta-glucuronidase activity, by a distinct protein and antigen profile, by an inability to grow on pectin as sole source of carbohydrate and by a markedly enhanced growth rate when supplied with a second carbohydrate (L-arabinose, D-galactose, D-glucose, D-fructose, D-mannitol, D-mannose, pectin, D-ribose or D-xylose) in addition to the essential GluA/GalA. By 16S rRNA sequencing these four isolates clustered in the recently described phylotype 'Smibert-2'. T. pectinovorum (14 strains) and 'Smibert-2' (four isolates with beta-glucuronidase activity) could each be subdivided into two serotypes based on immunoblot reactivity with two mAbs. Representatives of the two groups, including T. pectinovorum ATCC 33768T, showed a 1:2:1-type periplasmic flagellar arrangement. 'Smibert-2' is described as a novel species, Treponema parvum sp. nov., with isolate OMZ 833T (= ATCC 700770T) proposed as the type strain and OMZ 842 (= ATCC 700773) as reference strain for a second serotype.  (+info)

Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms. (4/22)

Cancrum oris (Noma) is a devastating infectious disease which destroys the soft and hard tissues of the oral and para-oral structures. The dehumanizing oro-facial gangrenous lesion affects predominantly children ages 2 to 16 years, particularly in sub-Saharan Africa, where the estimated frequency in some communities varies from 1 to 7 cases per 1000 population. The risk factors are poverty, malnutrition, poor oral hygiene, residential proximity to livestock in unsanitary environments, and infectious diseases, particularly measles and those due to the herpesviridae. Infections and malnutrition impair the immune system, and this is the common denominator for the occurrence of noma. Acute necrotizing gingivitis (ANG) and oral herpetic ulcers are considered the antecedent lesions, and ongoing studies suggest that the rapid progression of these precursor lesions to noma requires infection by a consortium of micro-organisms, with Fusobacterium necrophorum (Fn) and Prevotella intermedia (Pi) as the suspected key players. Additional to production of a growth-stimulating factor for Pi, Fn displays a classic endotoxin, a dermonecrotic toxin, a cytoplasmic toxin, and a hemolysin. Without appropriate treatment, the mortality rate from noma is 70-90%. Survivors suffer the two-fold afflictions of oro-facial mutilation and functional impairment, which require a time-consuming, financially prohibitive surgical reconstruction.  (+info)

Role of Treponema denticola in periodontal diseases. (5/22)

Among periodontal anaerobic pathogens, the oral spirochetes, and especially Treponema denticola, have been associated with periodontal diseases such as early-onset periodontitis, necrotizing ulcerative gingivitis, and acute pericoronitis. Basic research as well as clinical evidence suggest that the prevalence of T denticola, together with other proteolytic gram-negative bacteria in high numbers in periodontal pockets, may play an important role in the progression of periodontal disease. The accumulation of these bacteria and their products in the pocket may render the surface lining periodontal cells highly susceptible to lysis and damage. T. denticola has been shown to adhere to fibroblasts and epithelial cells, as well as to extracellular matrix components present in periodontal tissues, and to produce several deleterious factors that may contribute to the virulence of the bacteria. These bacterial components include outer-sheath-associated peptidases, chymotrypsin-like and trypsin-like proteinases, hemolytic and hemagglutinating activities, adhesins that bind to matrix proteins and cells, and an outer-sheath protein with pore-forming properties. The effects of T. denticola whole cells and their products on a variety of host mucosal and immunological cells has been studied extensively (Fig. 1). The clinical data regarding the presence of T. denticola in periodontal health and disease, together with the basic research results involving the role of T. denticola factors and products in relation to periodontal diseases, are reviewed and discussed in this article.  (+info)

Treponema putidum sp. nov., a medium-sized proteolytic spirochaete isolated from lesions of human periodontitis and acute necrotizing ulcerative gingivitis. (6/22)

So far, little phenotypic heterogeneity has been detected in cultured oral treponemes with trypsin-like proteolytic activity, and all have been assigned to the species Treponema denticola. However, comparisons of protein patterns and antigen expression in our collection of proteolytic oral treponemes occasionally identified isolates with a unique phenotype; e.g. strain OMZ 830 (=ATCC 700768), which qualified as a 'pathogen-related oral spirochaete' due to the presence of a approximately 37 kDa protein reactive with the Treponema pallidum FlaA-specific mAb H9-2. In addition to such single isolates, a homogeneous group of seven independent strains is described that were highly motile, medium-sized, proteolytic but asaccharolytic spirochaetes and were cultured from human gingivitis, periodontitis and acute necrotizing ulcerative gingivitis in medium OMIZ-Pat supplemented with 1% human serum and antibiotics. Growth of these spirochaetes in OMIZ-Pat was not dependent on, but was stimulated by, human or bovine serum. Carbohydrates were neither required nor stimulatory for growth. The protein and antigen patterns of total cell extracts of these organisms separated by SDS-PAGE were distinct from those of all previously cultured spirochaetes, with highest similarity to T. denticola. The novel spirochaete has a 2 : 4 : 2 arrangement of the periplasmic flagella, similar to T. denticola. However, the flagellin pattern as detected by immunostaining or glycan staining of Western blots readily distinguished the novel group from T. denticola. Also, distinct from reference strains of T. denticola, none of the novel isolates displayed sialidase or dentilisin activities, both of which are expressed by most strains of T. denticola. Trypsin-like activity and other enzymes as detected by API ZYM test were similar to those of T. denticola. The status of a novel species is supported by the 16S rRNA gene sequence, with 98.5% similarity to its closest cultured relative, T. denticola. The name Treponema putidum sp. nov. is proposed (type strain OMZ 758T=ATCC 700334T=CIP 108088T).  (+info)

Necrotising periodontal diseases. (7/22)

Necrotizing gingivitis (NG) or necrotising ulcerative gingivitis (NUG) is considered to be an acute opportunistic gingival infection caused by bacterial plaque. It appears more frequently in undernurished children and young adults as well as patients with immunodeficiency. In its pathogenesis, there are factors related to the oral microbiota with invasion processes on the one hand, and on the other hand, factors associated with the host, such as signs of capillary and immunological disorders as well as undernurishment. The disease is characterized by pain, bleeding and papillary necrosis with tendency to relapse. Diagnosis is made by a simple clinical examination. However, complementary tests ought to be performed in order to eliminate the possibility of illnesses systemic or immunodeficiency. Early and sustained treatment is strongly recommended. Lesions of the gums (craters in the interdental papillae) as an aftermath of the disease is a possibility, or if there is necrotizing periodontitis there will be loss of attachment tissue.  (+info)

Identification of spirochetes related to Treponema pallidum in necrotizing ulcerative gingivitis and chronic periodontitis. (8/22)

BACKGROUND: Spirochetes are commonly associated with periodontal disease, but it is not known whether these treponemes are pathogenic or merely opportunistic. We sought to determine whether spirochetes present in periodontal disease share antigens thought to be unique to spirochetes that are known pathogens. METHODS: We examined dental plaque from 24 healthy subjects, from ulcerative sites in 17 patients with ulcerative gingivitis, and from areas of involvement in 19 patients with chronic periodontitis, using an immunocyto-chemical technique with monoclonal antibodies against pathogen-specific determinants on 47-kd and 37-kd molecules from Treponema pallidum subspecies pallidum. Serum was tested against T. pallidum by immunoblotting and by serologic assays for syphilis. RESULTS: Spirochetes with a pathogen-specific epitope on a 47-kd molecule were not found in plaque samples from any of the 24 healthy subjects, but they were identified in plaque samples from 11 of 17 patients with ulcerative gingivitis (P less than 0.001) and from 10 of 19 patients with periodontitis (P less than 0.01). Monoclonal antibodies directed against a 37-kd molecule reacted with spirochetes in plaque samples from 1 of 14 controls, from all 11 patients with gingivitis from whom samples could be obtained (P less than 0.001), and from 14 of 19 patients with periodontitis (P less than 0.001). Five of 18 normal subjects had IgG against 47-kd and 37-kd molecules, but none had IgG against 14-kd or 12-kd molecules from T. pallidum subspecies pallidum. Among 19 patients with ulcerative gingivitis, IgG was identified against 47-kd molecules in 15, against 37-kd molecules in 12, against 14-kd molecules in 4, and against 12-kd molecules in 15. CONCLUSIONS: The spirochetes found in dental plaque from patients with ulcerative gingivitis or chronic periodontitis have antigens that are thought to be unique to pathogenic treponemes. This close antigenic relation suggests that T. pallidum or a closely related organism may be involved in the pathogenesis of periodontal disease.  (+info)

Gingivitis is a mild form of gum disease (periodontal disease) that causes irritation, redness, swelling and bleeding of the gingiva, or gums. It's important to note that it is reversible with good oral hygiene and professional dental treatment. If left untreated, however, gingivitis can progress to a more severe form of gum disease known as periodontitis, which can result in tissue damage and eventual tooth loss.

Gingivitis is most commonly caused by the buildup of plaque, a sticky film of bacteria that constantly forms on our teeth. When not removed regularly through brushing and flossing, this plaque can harden into tartar, which is more difficult to remove and contributes to gum inflammation. Other factors like hormonal changes, poor nutrition, certain medications, smoking or a weakened immune system may also increase the risk of developing gingivitis.

Necrotizing ulcerative gingivitis (NUG), also known as trench mouth or acute necrotizing ulcerative gingivostomatitis, is a severe and painful form of gingivitis that is characterized by the presence of necrosis (tissue death) and ulcers in the gum tissue. It is caused by a combination of factors, including poor oral hygiene, stress, smoking, and a weakened immune system. The condition is often associated with the presence of certain types of bacteria that produce toxins that can damage the gum tissue.

NUG is characterized by the sudden onset of symptoms such as severe pain, bleeding, bad breath, and a grayish-white or yellowish film covering the gums. The gums may also appear bright red, swollen, and shiny, and may bleed easily when brushed or touched. In some cases, the condition can progress to involve other areas of the mouth, such as the lining of the cheeks and lips.

NUG is typically treated with a combination of professional dental cleaning, antibiotics to eliminate the bacterial infection, and pain management. It is important to maintain good oral hygiene practices to prevent recurrence of the condition. If left untreated, NUG can lead to more serious complications such as tooth loss or spread of the infection to other parts of the body.

Necrotizing fasciitis is a serious bacterial infection that affects the fascia, which is the tissue that surrounds muscles, nerves, and blood vessels. The infection can also spread to the muscle and skin. It is often caused by a combination of different types of bacteria, including group A Streptococcus and Staphylococcus aureus.

The infection causes extensive tissue damage and necrosis (death) of the fascia and surrounding tissues. It can progress rapidly and can be fatal if not treated promptly with aggressive surgical debridement (removal of dead tissue) and antibiotics.

Symptoms of necrotizing fasciitis include severe pain, swelling, redness, and warmth in the affected area; fever; chills; and general weakness. It is important to seek medical attention immediately if these symptoms occur, as early diagnosis and treatment can significantly improve outcomes.

Necrotizing enterocolitis (NEC) is a serious gastrointestinal condition that primarily affects premature infants. It is characterized by the inflammation and death of intestinal tissue, which can lead to perforations (holes) in the bowel wall. Here's a brief medical definition:

Necrotizing enterocolitis (NEK-roh-tiz-ing en-ter-koh-li-TIE-tis): A gastrointestinal emergency in which the inner lining of the intestinal wall undergoes necrosis (tissue death) due to inflammation, often affecting premature infants. The condition may result in bowel perforations, sepsis, and other systemic complications, requiring surgical intervention and intensive care management.

The exact cause of NEC is not fully understood, but it's thought to be associated with factors such as prematurity, formula feeding, intestinal immaturity or injury, and disturbed blood flow in the intestines. Symptoms may include abdominal distention, bloody stools, feeding intolerance, lethargy, and temperature instability. Early recognition and prompt treatment are crucial for improving outcomes in affected infants.

Dental plaque is a biofilm or mass of bacteria that accumulates on the surface of the teeth, restorative materials, and prosthetic devices such as dentures. It is initiated when bacterial colonizers attach to the smooth surfaces of teeth through van der Waals forces and specific molecular adhesion mechanisms.

The microorganisms within the dental plaque produce extracellular polysaccharides that help to stabilize and strengthen the biofilm, making it resistant to removal by simple brushing or rinsing. Over time, if not regularly removed through oral hygiene practices such as brushing and flossing, dental plaque can mineralize and harden into tartar or calculus.

The bacteria in dental plaque can cause tooth decay (dental caries) by metabolizing sugars and producing acid that demineralizes the tooth enamel. Additionally, certain types of bacteria in dental plaque can cause periodontal disease, an inflammation of the gums that can lead to tissue damage and bone loss around the teeth. Regular professional dental cleanings and good oral hygiene practices are essential for preventing the buildup of dental plaque and maintaining good oral health.

Acute necrotizing pancreatitis is a severe and potentially life-threatening form of acute pancreatitis, which is an inflammatory condition of the pancreas. In acute necrotizing pancreatitis, there is widespread death (necrosis) of pancreatic tissue due to autodigestion caused by the activation and release of digestive enzymes within the pancreas. This condition can lead to systemic inflammation, organ failure, and infection of the necrotic areas in the pancreas. It typically has a more complicated clinical course and worse prognosis compared to acute interstitial pancreatitis, which is another form of acute pancreatitis without significant necrosis.

The dental plaque index (DPI) is a clinical measurement used in dentistry to assess the amount of dental plaque accumulation on a person's teeth. It was first introduced by Silness and Löe in 1964 as a method to standardize the assessment of oral hygiene and the effectiveness of oral hygiene interventions.

The DPI is based on a visual examination of the amount of plaque present on four surfaces of the teeth, including the buccal (cheek-facing) and lingual (tongue-facing) surfaces of both upper and lower first molars and upper and lower incisors. The examiner assigns a score from 0 to 3 for each surface, with higher scores indicating greater plaque accumulation:

* Score 0: No plaque detected, even after probing the area with a dental explorer.
* Score 1: Plaque detected by visual examination and/or probing but is not visible when the area is gently dried with air.
* Score 2: Moderate accumulation of soft deposits that are visible upon visual examination before air drying, but which can be removed by scraping with a dental explorer.
* Score 3: Abundant soft matter, visible upon visual examination before air drying and not easily removable with a dental explorer.

The DPI is calculated as the average score of all surfaces examined, providing an overall measure of plaque accumulation in the mouth. It can be used to monitor changes in oral hygiene over time or to evaluate the effectiveness of different oral hygiene interventions. However, it should be noted that the DPI has limitations and may not accurately reflect the presence of bacterial biofilms or the risk of dental caries and gum disease.

The Periodontal Index (PI) is not a current or widely used medical/dental term. However, in the past, it was used to describe a method for assessing and measuring the severity of periodontal disease, also known as gum disease.

Developed by Henry H. Klein and colleagues in 1978, the Periodontal Index was a scoring system that evaluated four parameters: gingival inflammation, gingival bleeding, calculus (tartar) presence, and periodontal pocket depths. The scores for each parameter ranged from 0 to 3, with higher scores indicating worse periodontal health. The overall PI score was the sum of the individual parameter scores, ranging from 0 to 12.

However, due to its limited ability to predict future disease progression and the introduction of more comprehensive assessment methods like the Community Periodontal Index (CPI) and the Basic Periodontal Examination (BPE), the use of the Periodontal Index has become less common in dental practice and research.

Gingival hemorrhage is the medical term for bleeding of the gingiva, or gums. It refers to the condition where the gums bleed, often as a result of trauma or injury, but also can be caused by various systemic conditions such as disorders of coagulation, leukemia, or scurvy.

Gingival hemorrhage is commonly seen in individuals with poor oral hygiene and periodontal disease, which can cause inflammation and damage to the gums. This can lead to increased susceptibility to bleeding, even during routine activities such as brushing or flossing. It's important to address any underlying causes of gingival hemorrhage to prevent further complications.

Gingival crevicular fluid (GCF) is defined as the serum transudate or inflammatory exudate that flows from the gingival sulcus or periodontal pocket. It is a physiological fluid found in the narrow space between the tooth and the surrounding gum tissue, which deepens during periodontal disease. The analysis of GCF has been used as a non-invasive method to assess the status of periodontal health and disease since it contains various markers of inflammation, host response, and bacterial products.

Periodontitis is a severe form of gum disease that damages the soft tissue and destroys the bone supporting your teeth. If left untreated, it can lead to tooth loss. It is caused by the buildup of plaque, a sticky film of bacteria that constantly forms on our teeth. The body's immune system fights the bacterial infection, which causes an inflammatory response. If the inflammation continues for a long time, it can damage the tissues and bones that support the teeth.

The early stage of periodontitis is called gingivitis, which is characterized by red, swollen gums that bleed easily when brushed or flossed. When gingivitis is not treated, it can advance to periodontitis. In addition to plaque, other factors that increase the risk of developing periodontitis include smoking or using tobacco products, poor oral hygiene, diabetes, a weakened immune system, and genetic factors.

Regular dental checkups and good oral hygiene practices, such as brushing twice a day, flossing daily, and using an antimicrobial mouth rinse, can help prevent periodontitis. Treatment for periodontitis may include deep cleaning procedures, medications, or surgery in severe cases.

Noma, also known as cancrum oris, is a rare but severe gangrenous disease that primarily affects children who are malnourished, have weakened immune systems, and lack access to proper oral hygiene and healthcare. The condition typically starts as a small ulcer in the mouth and quickly progresses, causing extensive tissue damage and necrosis of the soft and hard tissues of the face.

Noma can also affect the genital region (genital noma) or the anus (anorectal noma). The disease is caused by a polymicrobial infection, involving both aerobic and anaerobic bacteria, that thrive in necrotic tissue. If left untreated, noma can result in significant disfigurement, disability, and even death.

Early diagnosis and prompt treatment with antibiotics, surgery, and nutritional support are crucial to prevent the progression of the disease and improve the chances of a successful recovery. Preventive measures, such as improving oral hygiene, promoting access to healthcare, and addressing malnutrition, can help reduce the risk of noma in vulnerable populations.

A mouthwash is an antiseptic or therapeutic solution that is held in the mouth and then spit out, rather than swallowed. It is used to improve oral hygiene, to freshen breath, and to help prevent dental cavities, gingivitis, and other periodontal diseases.

Mouthwashes can contain a variety of ingredients, including water, alcohol, fluoride, chlorhexidine, essential oils, and other antimicrobial agents. Some mouthwashes are available over-the-counter, while others require a prescription. It is important to follow the instructions for use provided by the manufacturer or your dentist to ensure the safe and effective use of mouthwash.

Gingiva is the medical term for the soft tissue that surrounds the teeth and forms the margin of the dental groove, also known as the gum. It extends from the mucogingival junction to the base of the cervical third of the tooth root. The gingiva plays a crucial role in protecting and supporting the teeth and maintaining oral health by providing a barrier against microbial invasion and mechanical injury.

According to the American Academy of Periodontology, periodontal diseases are chronic inflammatory conditions that affect the tissues surrounding and supporting the teeth. These tissues include the gums, periodontal ligament, and alveolar bone. The primary cause of periodontal disease is bacterial plaque, a sticky film that constantly forms on our teeth.

There are two major stages of periodontal disease:

1. Gingivitis: This is the milder form of periodontal disease, characterized by inflammation of the gums (gingiva) without loss of attachment to the teeth. The gums may appear red, swollen, and bleed easily during brushing or flossing. At this stage, the damage can be reversed with proper dental care and improved oral hygiene.
2. Periodontitis: If left untreated, gingivitis can progress to periodontitis, a more severe form of periodontal disease. In periodontitis, the inflammation extends beyond the gums and affects the deeper periodontal tissues, leading to loss of bone support around the teeth. Pockets filled with infection-causing bacteria form between the teeth and gums, causing further damage and potential tooth loss if not treated promptly.

Risk factors for developing periodontal disease include poor oral hygiene, smoking or using smokeless tobacco, genetic predisposition, diabetes, hormonal changes (such as pregnancy or menopause), certain medications, and systemic diseases like AIDS or cancer. Regular dental check-ups and good oral hygiene practices are crucial for preventing periodontal disease and maintaining overall oral health.

Chronic periodontitis is a type of gum disease that is characterized by the inflammation and infection of the tissues surrounding and supporting the teeth. It is a slow-progressing condition that can lead to the destruction of the periodontal ligament and alveolar bone, which can result in loose teeth or tooth loss if left untreated.

Chronic periodontitis is caused by the buildup of dental plaque and calculus (tartar) on the teeth, which harbor bacteria that release toxins that irritate and inflame the gums. Over time, this chronic inflammation can lead to the destruction of the periodontal tissues, including the gingiva, periodontal ligament, and alveolar bone.

The signs and symptoms of chronic periodontitis include:

* Red, swollen, or tender gums
* Bleeding gums during brushing or flossing
* Persistent bad breath (halitosis)
* Receding gums (exposure of the tooth root)
* Loose teeth or changes in bite alignment
* Deep periodontal pockets (spaces between the teeth and gums)

Risk factors for chronic periodontitis include poor oral hygiene, smoking, diabetes, genetics, and certain medications. Treatment typically involves a thorough dental cleaning to remove plaque and calculus, followed by additional procedures such as scaling and root planing or surgery to eliminate infection and promote healing of the periodontal tissues. Good oral hygiene practices, regular dental checkups, and quitting smoking are essential for preventing chronic periodontitis and maintaining good oral health.

I'm sorry for any confusion, but "toothpastes" is the plural form of "toothpaste," which is not a medical condition or procedure that requires a definition. However, I can provide you with some information about toothpaste.

Toothpaste is a dental hygiene product used to clean and maintain the health of teeth and gums. It generally contains mild abrasives, flavoring, and fluoride to help remove plaque, prevent tooth decay, and freshen breath. There are various types of toothpastes available on the market, including those formulated for sensitive teeth, whitening, gum health, and tartar control. It is essential to choose a toothpaste that meets your specific dental needs and has the American Dental Association (ADA) Seal of Acceptance, ensuring its safety and effectiveness.

Prevotella intermedia is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found in the oral cavity, upper respiratory tract, and gastrointestinal tract. It is a normal resident of the human microbiota but can also be an opportunistic pathogen, causing various types of infections such as periodontitis, endocarditis, and brain abscesses. P. intermedia has been associated with several diseases, including respiratory tract infections, bacteremia, and joint infections. It is often found in mixed infections with other anaerobic bacteria. Proper identification of this organism is important for the selection of appropriate antimicrobial therapy.

Periodontal attachment loss (PAL) is a clinical measurement in dentistry that refers to the amount of connective tissue attachment between the tooth and its surrounding supportive structures (including the gingiva, periodontal ligament, and alveolar bone) that has been lost due to periodontal disease. It is typically expressed in millimeters and represents the distance from the cementoenamel junction (CEJ), which is the point where the tooth's crown meets the root, to the bottom of the periodontal pocket.

Periodontal pockets are formed when the gums detach from the tooth due to inflammation and infection caused by bacterial biofilms accumulating on the teeth. As the disease progresses, more and more of the supporting structures are destroyed, leading to increased pocket depths and attachment loss. This can eventually result in loose teeth and even tooth loss if left untreated.

Therefore, periodontal attachment loss is an important indicator of the severity and progression of periodontal disease, and its measurement helps dental professionals assess the effectiveness of treatment interventions and monitor disease status over time.

Necrosis is the premature death of cells or tissues due to damage or injury, such as from infection, trauma, infarction (lack of blood supply), or toxic substances. It's a pathological process that results in the uncontrolled and passive degradation of cellular components, ultimately leading to the release of intracellular contents into the extracellular space. This can cause local inflammation and may lead to further tissue damage if not treated promptly.

There are different types of necrosis, including coagulative, liquefactive, caseous, fat, fibrinoid, and gangrenous necrosis, each with distinct histological features depending on the underlying cause and the affected tissues or organs.

Dental calculus, also known as tartar, is a hardened deposit that forms on the surface of teeth. It's composed of mineralized plaque, which is a sticky film containing bacteria, saliva, and food particles. Over time, the minerals in saliva can cause the plaque to harden into calculus, which cannot be removed by brushing or flossing alone. Dental calculus can contribute to tooth decay and gum disease if not regularly removed by a dental professional through a process called scaling and root planing.

The Oral Hygiene Index (OHI) is a dental measurement used to assess and quantify the cleanliness of a patient's teeth. It was developed by Greene and Vermillion in 1964 as a simple, reproducible method for oral hygiene evaluation. The index takes into account the amount of debris (food particles, plaque) and calculus (tartar) present on the tooth surfaces.

The OHI consists of two components: the Debris Index (DI) and the Calculus Index (CI). Each component is scored separately for six designated teeth (16, 11, 26, 36, 31, and 46) on a scale from 0 to 3. The scores are then summed up and averaged to obtain the final OHI score:

1. Debris Index (DI): Assesses the soft debris or plaque accumulation on the tooth surfaces. The scoring is as follows:
- Score 0: No debris present
- Score 1: Debris found on up to one-third of the tooth surface
- Score 2: Debris found on more than one-third but less than two-thirds of the tooth surface
- Score 3: Debris found on more than two-thirds of the tooth surface

2. Calculus Index (CI): Evaluates the hard calculus or tartar accumulation on the tooth surfaces. The scoring is similar to the DI:
- Score 0: No calculus present
- Score 1: Supragingival calculus found on up to one-third of the tooth surface
- Score 2: Supragingival calculus found on more than one-third but less than two-thirds of the tooth surface, or the presence of individual flecks of subgingival calculus
- Score 3: Supragingival calculus found on more than two-thirds of the tooth surface, or a continuous heavy band of subgingival calculus

The OHI score ranges from 0 to 6, with higher scores indicating poorer oral hygiene. This index is widely used in dental research and clinical settings to evaluate the effectiveness of oral hygiene interventions and to assess overall oral health status.

A periodontal pocket is a pathological space or gap that develops between the tooth and the surrounding gum tissue (gingiva) as a result of periodontal disease. This condition is also known as a "periodontal depth" or "probing depth." It is measured in millimeters using a dental probe, and it indicates the level of attachment loss of the gingival tissue to the tooth.

In a healthy periodontium, the sulcus (the normal space between the tooth and gum) measures 1-3 mm in depth. However, when there is inflammation due to bacterial accumulation, the gums may become red, swollen, and bleed easily. As the disease progresses, the sulcus deepens, forming a periodontal pocket, which can extend deeper than 3 mm.

Periodontal pockets provide an environment that is conducive to the growth of harmful bacteria, leading to further tissue destruction and bone loss around the tooth. If left untreated, periodontal disease can result in loose teeth and eventually tooth loss. Regular dental check-ups and professional cleanings are essential for maintaining healthy gums and preventing periodontal pockets from developing or worsening.

Dentifrices are substances used in dental care for cleaning and polishing the teeth, and often include toothpastes, tooth powders, and gels. They typically contain a variety of ingredients such as abrasives, fluorides, humectants, detergents, flavorings, and sometimes medicaments like antimicrobial agents or desensitizing compounds. The primary purpose of dentifrices is to help remove dental plaque, food debris, and stains from the teeth, promoting oral hygiene and preventing dental diseases such as caries (cavities) and periodontal disease.

Necrotizing sialometaplasia is a relatively uncommon, self-limiting condition that primarily affects the salivary glands. It is typically characterized by the presence of necrosis (tissue death) and metaplastic changes in the salivary gland tissue, particularly within the minor salivary glands located in the upper aerodigestive tract.

The condition often manifests as a sudden onset of painful swelling in the affected area, such as the palate, lips, or tongue. This is followed by the development of necrosis and metaplastic changes in the salivary gland tissue, which can lead to the formation of ulcers or pseudocarcinomatous lesions that may resemble malignant tumors.

Necrotizing sialometaplasia is thought to be caused by local ischemia (reduced blood flow) or injury to the salivary glands, and it is often associated with a history of recent trauma, surgery, or radiation therapy in the affected area. However, in some cases, the condition may occur spontaneously without any obvious triggering factor.

Despite its sometimes alarming appearance, necrotizing sialometaplasia is generally a benign and self-limiting condition that does not require specific treatment beyond symptomatic management of pain and discomfort. The lesions typically resolve on their own within 4-6 weeks, although in some cases they may persist for several months before ultimately regressing.

Bacteroidaceae is a family of gram-negative, anaerobic or facultatively anaerobic, non-spore forming bacteria that are commonly found in the human gastrointestinal tract. They are rod-shaped and can vary in size and shape. Bacteroidaceae are important breakdowners of complex carbohydrates and proteins in the gut, and play a significant role in maintaining the health and homeostasis of the intestinal microbiota. Some members of this family can also be opportunistic pathogens and have been associated with various infections and diseases, such as abscesses, bacteremia, and periodontal disease.

Oral hygiene is the practice of keeping the mouth and teeth clean to prevent dental issues such as cavities, gum disease, bad breath, and other oral health problems. It involves regular brushing, flossing, and using mouthwash to remove plaque and food particles that can lead to tooth decay and gum disease. Regular dental check-ups and cleanings are also an essential part of maintaining good oral hygiene. Poor oral hygiene can lead to a range of health problems, including heart disease, diabetes, and respiratory infections, so it is important to prioritize oral health as part of overall health and wellbeing.

Treponemal infections are a group of diseases caused by the spirochete bacterium Treponema pallidum. This includes syphilis, yaws, bejel, and pinta. These infections can affect various organ systems in the body and can have serious consequences if left untreated.

1. Syphilis: A sexually transmitted infection that can also be passed from mother to fetus during pregnancy or childbirth. It is characterized by sores (chancres) on the genitals, anus, or mouth, followed by a rash and flu-like symptoms. If left untreated, it can lead to serious complications such as damage to the heart, brain, and nervous system.
2. Yaws: A tropical infection that is spread through direct contact with infected skin lesions. It primarily affects children in rural areas of Africa, Asia, and South America. The initial symptom is a painless bump on the skin that eventually ulcerates and heals, leaving a scar. If left untreated, it can lead to disfigurement and destruction of bone and cartilage.
3. Bejel: Also known as endemic syphilis, this infection is spread through direct contact with infected saliva or mucous membranes. It primarily affects children in dry and arid regions of Africa, the Middle East, and Asia. The initial symptom is a painless sore on the mouth or skin, followed by a rash and other symptoms similar to syphilis.
4. Pinta: A tropical infection that is spread through direct contact with infected skin lesions. It primarily affects people in rural areas of Central and South America. The initial symptom is a red or brown spot on the skin, which eventually turns into a scaly rash. If left untreated, it can lead to disfigurement and destruction of pigmentation in the skin.

Treponemal infections can be diagnosed through blood tests that detect antibodies against Treponema pallidum. Treatment typically involves antibiotics such as penicillin, which can cure the infection if caught early enough. However, untreated treponemal infections can lead to serious health complications and even death.

Fusobacterium is a genus of obligate anaerobic, gram-negative, non-spore forming bacilli that are commonly found as normal flora in the human oral cavity, gastrointestinal tract, and female genital tract. Some species of Fusobacterium have been associated with various clinical infections and diseases, such as periodontal disease, abscesses, bacteremia, endocarditis, and inflammatory bowel disease.

Fusobacterium nucleatum is the most well-known species in this genus and has been extensively studied for its role in various diseases. It is a opportunistic pathogen that can cause severe infections in immunocompromised individuals or when it invades damaged tissues. Fusobacterium necrophorum, another important species, is a leading cause of Lemierre's syndrome, a rare but serious condition characterized by septic thrombophlebitis of the internal jugular vein and metastatic infections.

Fusobacteria are known to have a complex relationship with other microorganisms and host cells, and they can form biofilms that contribute to their virulence and persistence in the host. Further research is needed to fully understand the pathogenic mechanisms of Fusobacterium species and to develop effective strategies for prevention and treatment of Fusobacterium-associated diseases.

"Prevotella nigrescens" is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found in the human oral cavity, intestinal tract, and female genital tract. It is a member of the normal microbiota of these areas but has been associated with various infections such as periodontitis, endodontic infections, aspiration pneumonia, and bacteremia. The bacterium can also be found in association with abscesses, wound infections, and other types of soft tissue infections. It is important to note that the presence of "Prevotella nigrescens" alone does not necessarily indicate infection, as it can also be present in the absence of disease. However, its identification in clinical specimens may warrant further investigation and appropriate treatment.

Treponema denticola is a gram-negative, spiral-shaped bacterium that belongs to the genus Treponema. It is commonly found in the oral cavity and is associated with periodontal diseases such as chronic periodontitis. T. denticola is one of the "red complex" bacteria, which also includes Porphyromonas gingivalis and Tannerella forsythia, that are strongly associated with periodontal disease. These bacteria form a complex biofilm in the subgingival area and contribute to the breakdown of the periodontal tissues, leading to pocket formation, bone loss, and ultimately tooth loss if left untreated.

T. denticola has several virulence factors, including lipopolysaccharides (LPS), proteases, fimbriae, and endotoxins, that allow it to evade the host's immune system and cause tissue damage. It can also modulate the host's immune response, leading to a chronic inflammatory state that contributes to the progression of periodontal disease.

In addition to its role in periodontal disease, T. denticola has been linked to several systemic diseases, including cardiovascular disease, diabetes, and rheumatoid arthritis. However, more research is needed to fully understand the relationship between T. denticola and these conditions.

Dental devices for home care are products designed for use by individuals or their caregivers in a home setting to maintain oral hygiene, manage dental health issues, and promote overall oral health. These devices can include:

1. Toothbrushes: Manual, electric, or battery-operated toothbrushes used to clean teeth and remove plaque and food debris.
2. Dental floss: A thin string used to remove food particles and plaque from between the teeth and under the gum line.
3. Interdental brushes: Small brushes designed to clean between the teeth and around dental appliances, such as braces or implants.
4. Water flossers/oral irrigators: Devices that use a stream of water to remove food particles and plaque from between the teeth and under the gum line.
5. Tongue scrapers: Tools used to clean the tongue's surface, removing bacteria and reducing bad breath.
6. Rubber tips/gum stimulators: Devices used to massage and stimulate the gums, promoting blood circulation and helping to maintain gum health.
7. Dental picks/sticks: Pointed tools used to remove food particles and plaque from between the teeth and under the gum line.
8. Mouthguards: Protective devices worn over the teeth to prevent damage from grinding, clenching, or sports-related injuries.
9. Night guards: Similar to mouthguards, these are designed to protect the teeth from damage caused by nighttime teeth grinding (bruxism).
10. Dental retainers: Devices used to maintain the alignment of teeth after orthodontic treatment.
11. Whitening trays and strips: At-home products used to whiten teeth by applying a bleaching agent to the tooth surface.
12. Fluoride mouth rinses: Anticavity rinses containing fluoride, which help strengthen tooth enamel and prevent decay.
13. Oral pain relievers: Topical gels or creams used to alleviate oral pain, such as canker sores or denture irritation.

Proper use of these dental devices, along with regular dental check-ups and professional cleanings, can help maintain good oral health and prevent dental issues.

Anti-infective agents, local, are medications that are applied directly to a specific area of the body to prevent or treat infections caused by bacteria, fungi, viruses, or parasites. These agents include topical antibiotics, antifungals, antivirals, and anti-parasitic drugs. They work by killing or inhibiting the growth of the infectious organisms, thereby preventing their spread and reducing the risk of infection. Local anti-infective agents are often used to treat skin infections, eye infections, and other localized infections, and can be administered as creams, ointments, gels, solutions, or drops.

Veillonella is a genus of Gram-negative, anaerobic, non-spore-forming, coccoid or rod-shaped bacteria. These bacteria are commonly found as normal flora in the human mouth, intestines, and female genital tract. They are known to be obligate parasites, meaning they rely on other organisms for nutrients and energy. Veillonella species are often associated with dental caries and have been implicated in various infections such as bacteremia, endocarditis, pneumonia, and wound infections, particularly in immunocompromised individuals or those with underlying medical conditions. Proper identification of Veillonella species is important for the diagnosis and treatment of these infections.

Clobetasol is a topical corticosteroid medication that is used to reduce inflammation and relieve itching, redness, and swelling associated with various skin conditions. It works by suppressing the immune system's response to reduce inflammation. Clobetasol is available in several forms, including creams, ointments, emulsions, and foams, and is usually applied to the affected area once or twice a day.

It is important to use clobetasol only as directed by a healthcare provider, as prolonged or excessive use can lead to thinning of the skin, increased susceptibility to infections, and other side effects. Additionally, it should not be used on large areas of the body or for extended periods without medical supervision.

Tooth diseases are conditions that affect the teeth and can cause discomfort, pain, and even loss of teeth if left untreated. These diseases can be caused by various factors such as poor oral hygiene, bacterial infections, trauma, genetics, and certain medical conditions. Some common tooth diseases include:

1. Dental caries (tooth decay): This is a breakdown of the tooth enamel due to the action of acid-producing bacteria that feed on sugars and starches in the mouth. Over time, this can lead to cavities or holes in the teeth.
2. Gingivitis: This is an inflammation of the gums caused by the buildup of plaque and tartar at the gum line. If left untreated, gingivitis can progress to periodontitis, a more serious form of gum disease that can cause tooth loss.
3. Periodontitis: This is a severe infection of the gums and bones that support the teeth. It is caused by the buildup of plaque and tartar, which leads to the destruction of the tissue and bone that hold the teeth in place.
4. Abscess: This is a pocket of pus that forms in the tooth or gum due to a bacterial infection. An abscess can cause pain, swelling, and fever, and may require antibiotics or surgical drainage.
5. Tooth erosion: This is the loss of tooth structure due to acid wear, which can be caused by factors such as diet, stomach acid, and teeth grinding.
6. Hypersensitivity: This is a condition in which the teeth become sensitive to hot, cold, or sweet foods and drinks. It can be caused by factors such as gum recession, tooth decay, and tooth wear.
7. Oral cancer: This is a type of cancer that affects the mouth, lips, tongue, or throat. It can cause symptoms such as sores, lumps, or difficulty swallowing, and may require surgery, radiation therapy, or chemotherapy for treatment.

Acute hemorrhagic leukoencephalitis (AHLE) is a rare and severe inflammatory disease of the central nervous system, characterized by extensive hemorrhage (bleeding) and destruction of the white matter in the brain. It is considered a hyperacute form of necrotizing vasculitis, which affects small blood vessels in the brain, leading to their rupture and subsequent bleeding into the surrounding white matter.

AHLE typically presents with sudden onset of symptoms, including fever, headache, altered mental status, seizures, focal neurological deficits, and signs of increased intracranial pressure. The condition can rapidly progress to coma and death within a few days if not promptly diagnosed and treated.

The exact cause of AHLE remains unclear; however, it is often associated with or preceded by an upper respiratory tract infection, suggesting a possible post-infectious immune-mediated etiology. Some cases have been linked to specific pathogens, such as influenza A virus and Mycoplasma pneumoniae.

Treatment typically involves high-dose corticosteroids, immunoglobulins, plasma exchange, and sometimes additional immunosuppressive therapies to control the inflammatory response. Supportive care, including management of increased intracranial pressure and prevention of complications, is also crucial for patient survival. Despite treatment, AHLE has a high mortality rate, and survivors often experience significant neurological sequelae.

Treponema is a genus of spiral-shaped bacteria, also known as spirochetes. These bacteria are gram-negative and have unique motility provided by endoflagella, which are located in the periplasmic space, running lengthwise between the cell's outer membrane and inner membrane.

Treponema species are responsible for several important diseases in humans, including syphilis (Treponema pallidum), yaws (Treponema pertenue), pinta (Treponema carateum), and endemic syphilis or bejel (Treponema pallidum subspecies endemicum). These diseases are collectively known as treponematoses.

It is important to note that while these bacteria share some common characteristics, they differ in their clinical manifestations and geographical distributions. Proper diagnosis and treatment of treponemal infections require medical expertise and laboratory confirmation.

Histiocytic Necrotizing Lymphadenitis is a condition characterized by the inflammation and necrosis (death of tissue) of lymph nodes, caused by an abnormal proliferation and activation of histiocytes (a type of white blood cell). It is also known as Kikuchi's disease. The exact cause of this condition is unknown, but it is thought to be related to an immune response to viral infections or other antigens.

Histopathologically, it is characterized by the presence of necrotizing granulomatous inflammation with histiocytic predominance and absence of neutrophils. The condition is typically self-limiting, with symptoms resolving within a few months without specific treatment. However, in some cases, it can be associated with systemic symptoms or other autoimmune disorders.

Fasciitis is a medical condition characterized by inflammation or irritation of the fascia, which are the bands of connective tissue that surround muscles, tendons, and bones in the body. The most common type of fasciitis is plantar fasciitis, which affects the fascia on the bottom of the foot and can cause heel pain. Other types of fasciitis include:

* Achilles tendonitis or Achilles tendinopathy, which affects the fascia that connects the calf muscle to the heel bone
* Shin splints, which affect the fascia that covers the front of the lower leg
* Necrotizing fasciitis, a rare and serious bacterial infection that can cause extensive tissue damage and is potentially life-threatening.

The symptoms of fasciitis may include pain, stiffness, or tenderness in the affected area, especially after prolonged periods of rest or physical activity. Treatment for fasciitis typically involves rest, ice, compression, and elevation (RICE) of the affected area, as well as physical therapy exercises to stretch and strengthen the fascia and surrounding muscles. In some cases, medication or surgery may be necessary to relieve symptoms and promote healing.

Debridement is a medical procedure that involves the removal of dead, damaged, or infected tissue to improve the healing process or prevent further infection. This can be done through various methods such as surgical debridement (removal of tissue using scalpel or scissors), mechanical debridement (use of wound irrigation or high-pressure water jet), autolytic debridement (using the body's own enzymes to break down and reabsorb dead tissue), and enzymatic debridement (application of topical enzymes to dissolve necrotic tissue). The goal of debridement is to promote healthy tissue growth, reduce the risk of infection, and improve overall wound healing.

Toothbrushing is the act of cleaning teeth and gums using a toothbrush to remove plaque, food debris, and dental calculus (tartar) from the surfaces of the teeth and gums. It is typically performed using a soft-bristled toothbrush and fluoride toothpaste, with gentle circular or back-and-forth motions along the gumline and on all surfaces of the teeth. Toothbrushing should be done at least twice a day, preferably after every meal and before bedtime, for two minutes each time, to maintain good oral hygiene and prevent dental diseases such as tooth decay and gum disease. It is also recommended to brush the tongue to remove bacteria and freshen breath.

Gingival hyperplasia is a condition characterized by an abnormal growth or enlargement of the gingiva (gum tissue). This condition can be caused by various factors, including bacterial infection, certain medications (such as phenytoin, cyclosporine, and nifedipine), systemic diseases (such as leukemia, vitamin C deficiency, and Crohn's disease), and genetic disorders.

The enlarged gum tissue can be uncomfortable, irritated, and prone to bleeding, especially during brushing or flossing. It may also make it difficult to maintain good oral hygiene, which can increase the risk of dental caries and periodontal disease. Treatment for gingival hyperplasia typically involves improving oral hygiene, controlling any underlying causes, and in some cases, surgical removal of the excess tissue.

Mouth diseases refer to a variety of conditions that affect the oral cavity, including the lips, gums, teeth, tongue, palate, and lining of the mouth. These diseases can be caused by bacteria, viruses, fungi, or other organisms. They can also result from injuries, chronic illnesses, or genetic factors.

Some common examples of mouth diseases include dental caries (cavities), periodontal disease (gum disease), oral herpes, candidiasis (thrush), lichen planus, and oral cancer. Symptoms may include pain, swelling, redness, bleeding, bad breath, difficulty swallowing or speaking, and changes in the appearance of the mouth or teeth. Treatment depends on the specific diagnosis and may involve medications, dental procedures, or lifestyle changes.

Aggressive periodontitis is a severe form of periodontal disease that affects the tissues surrounding and supporting the teeth, including the gums, periodontal ligament, and alveolar bone. It is characterized by rapid destruction of the periodontal tissues and can result in significant tooth loss if left untreated.

Aggressive periodontitis typically affects younger individuals, often before the age of 30, and can progress rapidly, even in the absence of obvious dental plaque or calculus accumulation. It is often associated with a genetic predisposition and may cluster in families.

The disease is classified as localized or generalized based on the distribution of affected sites. Localized aggressive periodontitis typically affects no more than two teeth next to each other, while generalized aggressive periodontitis involves at least three or four teeth in different areas of the mouth.

In addition to genetic factors, other risk factors for aggressive periodontitis include smoking, diabetes, and hormonal changes. Treatment typically involves a combination of thorough dental cleanings, antibiotics, and sometimes surgical intervention to remove damaged tissue and promote healing. Regular maintenance care is essential to prevent recurrence and further progression of the disease.

Pericoronitis is a dental condition characterized by inflammation of the tissue around the crown of a tooth, usually affecting the lower wisdom teeth that have only partially erupted through the gum line. The term "peri" means around, and "coron" refers to the crown of the tooth.

In pericoronitis, the gum tissues surrounding the affected tooth become red, swollen, and painful due to bacterial infection and accumulation of debris under the gum flap (operculum) covering the partially erupted tooth. This condition can lead to complications such as difficulty in chewing, swallowing, and speaking, as well as trismus (restricted jaw movement), pus discharge, and fever in severe cases.

Treatment for pericoronitis typically involves removing the source of irritation and infection, which may include professional dental cleaning, irrigation, and antibiotics to manage the infection. In some instances, surgical removal of the affected tooth or operculum may be necessary to alleviate symptoms and prevent future recurrences.

Calendula, also known as pot marigold (Calendula officinalis), is a plant that is part of the Asteraceae/Compositae family. It is often used in herbal medicine and has been utilized for various medicinal purposes due to its anti-inflammatory, antimicrobial, and antioxidant properties. Calendula extracts or ointments are sometimes applied topically to help heal wounds, burns, rashes, and other skin irritations. However, it's essential to consult a healthcare professional before using calendula for medicinal purposes, as it may interact with certain medications or have adverse effects in some individuals.

Polyarteritis nodosa (PAN) is a rare, systemic necrotizing vasculitis that affects medium-sized and small muscular arteries. It is characterized by inflammation and damage to the walls of the arteries, leading to the formation of microaneurysms (small bulges in the artery wall) and subsequent narrowing or complete occlusion of the affected vessels. This can result in tissue ischemia (reduced blood flow) and infarction (tissue death), causing a wide range of clinical manifestations that vary depending on the organs involved.

The exact cause of PAN remains unclear, but it is believed to involve an autoimmune response triggered by various factors such as infections or exposure to certain drugs. The diagnosis of PAN typically requires a combination of clinical findings, laboratory tests, and imaging studies, often supported by histopathological examination of affected tissues. Treatment usually involves the use of immunosuppressive medications to control inflammation and prevent further damage to the arteries and organs.

Dental scaling is a professional dental cleaning procedure that involves the removal of plaque, tartar (calculus), and stains from the tooth surfaces. This is typically performed by a dentist or dental hygienist using specialized instruments called scalers and curettes. The procedure helps to prevent gum disease and tooth decay by removing bacterial deposits that can cause inflammation and infection of the gums. Dental scaling may be recommended as part of a routine dental check-up or if there are signs of periodontal disease, such as red, swollen, or bleeding gums. In some cases, local anesthesia may be used to numb the area and make the procedure more comfortable for the patient.

Gingival diseases are infections or inflammations that affect the gingiva, which is the part of the gum around the base of the teeth. These diseases can be caused by bacteria found in dental plaque and can lead to symptoms such as redness, swelling, bleeding, and receding gums. If left untreated, gingival diseases can progress to periodontal disease, a more serious condition that can result in tooth loss. Common types of gingival diseases include gingivitis and periodontitis.

I'm sorry for any confusion, but "Tin Fluorides" is not a widely recognized medical term or concept. Tin (Sn) and Fluoride (F-) are both chemical elements that can form various compounds together, such as tin(II) fluoride (SnF2) and tin(IV) fluoride (SnF4). These compounds have uses in industrial applications, but they are not typically associated with medical definitions.

Tin(II) fluoride, for example, is used in some toothpastes and dental products as a fluoride source to help prevent tooth decay. However, it's important to note that the medical definition of a substance like this would be more focused on its clinical use or effect, rather than its chemical composition alone.

If you have any questions about specific tin-fluoride compounds and their potential uses or effects in a medical context, I would recommend consulting a healthcare professional or a reliable source of information on pharmaceuticals or medical treatments.

Spirochaetaceae is a family of spiral-shaped, gram-negative bacteria known as spirochetes. These bacteria are characterized by their unique morphology, which includes a flexible helical shape and the presence of endoflagella, which are located inside the cell wall and run lengthwise along the entire length of the organism. This arrangement of flagella allows the spirochete to move in a corkscrew-like motion.

Spirochaetaceae includes several genera of medically important bacteria, such as:

* Treponema: This genus includes the bacterium that causes syphilis (Treponema pallidum) and other treponemal diseases like yaws and pinta.
* Borrelia: This genus includes the spirochetes responsible for Lyme disease (Borrelia burgdorferi) and relapsing fever (Borrelia recurrentis).
* Leptospira: This genus contains the bacteria that cause leptospirosis, a zoonotic disease transmitted through the urine of infected animals.

Spirochetes are often found in aquatic environments and can be part of the normal microbiota of some animals, including humans. However, certain species can cause significant diseases in humans and animals, making them important pathogens. Proper identification and appropriate antibiotic treatment are crucial for managing spirochetal infections.

'Salvia officinalis', also known as garden sage or common sage, is not a medical condition but an herb that has been used in traditional medicine. Here's the botanical definition:

Salvia officinalis, commonly known as sage, garden sage, or common sage, is a perennial, evergreen subshrub, with woody stems, grayish leaves, and blue to purplish flowers. It belongs to the Lamiaceae family, also known as the mint family. The plant is native to the Mediterranean region and has been cultivated throughout the world for its aromatic leaves, which are used in cooking, cosmetics, and medicinal preparations.

In traditional medicine, sage leaves have been used to treat various conditions, such as sore throats, coughs, colds, and digestive issues. However, it is essential to note that the effectiveness of sage for these uses has not been thoroughly studied in clinical trials, and its use should not replace conventional medical care. Always consult with a healthcare professional before starting any new treatment or therapy.

Papaveraceae is a family of flowering plants, also known as the poppy family. It includes annuals, biennials, and perennials with showy flowers and often milky sap. The family contains around 770 species in 42 genera, including some well-known plants such as opium poppy (Papaver somniferum), corn poppy (Papaver rhoeas), and Iceland poppy (Papaver nudicaule). The plants in this family have simple or compound leaves, and their flowers usually have four or six petals. Some members of Papaveraceae are cultivated for their ornamental value, while others produce valuable medicinal compounds such as opium alkaloids.

Cytotoxins are substances that are toxic to cells. They can cause damage and death to cells by disrupting their membranes, interfering with their metabolism, or triggering programmed cell death (apoptosis). Cytotoxins can be produced by various organisms such as bacteria, fungi, plants, and animals, and they can also be synthesized artificially.

In medicine, cytotoxic drugs are used to treat cancer because they selectively target and kill rapidly dividing cells, including cancer cells. Examples of cytotoxic drugs include chemotherapy agents such as doxorubicin, cyclophosphamide, and methotrexate. However, these drugs can also damage normal cells, leading to side effects such as nausea, hair loss, and immune suppression.

It's important to note that cytotoxins are not the same as toxins, which are poisonous substances produced by living organisms that can cause harm to other organisms. While all cytotoxins are toxic to cells, not all toxins are cytotoxic. Some toxins may have systemic effects on organs or tissues rather than directly killing cells.

Actinomyces is a genus of gram-positive, rod-shaped bacteria that are normal inhabitants of the human mouth, colon, and urogenital tract. Under certain conditions, such as poor oral hygiene or tissue trauma, these bacteria can cause infections known as actinomycosis. These infections often involve the formation of abscesses or granulomas and can affect various tissues, including the lungs, mouth, and female reproductive organs. Actinomyces species are also known to form complex communities called biofilms, which can contribute to their ability to cause infection.

Cetylpyridinium is an antimicrobial compound that is commonly used in oral healthcare products such as mouthwashes, toothpastes, and lozenges. It works by disrupting the bacterial cell membrane, leading to the death of the microorganism. Cetylpyridinium has been shown to be effective against a variety of bacteria, fungi, and viruses, making it a popular ingredient in products designed to maintain oral hygiene and prevent infection.

The chemical name for cetylpyridinium is cetylpyridinium chloride (CPC), and it has the molecular formula C16H37NClO. It is a cationic surfactant, which means that it contains positively charged ions that can interact with negatively charged bacterial cell membranes. This interaction disrupts the membrane's structure, leading to the leakage of cellular components and the death of the microorganism.

Cetylpyridinium is generally considered safe for use in oral healthcare products, although it can cause irritation in some people. It is important to follow the instructions on any product containing cetylpyridinium carefully, as overuse or improper use may lead to adverse effects. Additionally, it is always a good idea to consult with a healthcare professional before using any new medication or healthcare product, especially if you have any pre-existing medical conditions or are taking other medications.

I'm sorry for any confusion, but "Niger" is not a medical term. It is the name of a country located in West Africa, officially known as the Republic of Niger. If you have any questions about medical terminology or health-related topics, please provide more details and I would be happy to help.

An oral ulcer is a defect or break in the continuity of the epithelium, the tissue that lines the inner surface of the mouth, leading to an inflamed, painful, and sometimes bleeding lesion. They can be classified as primary (e.g., aphthous ulcers, traumatic ulcers) or secondary (e.g., those caused by infections, underlying systemic conditions, or reactions to medications). Oral ulcers may cause discomfort, impacting speech and food consumption, and their presence might indicate an underlying medical issue that requires further evaluation.

Bacteroidaceae is a family of gram-negative, anaerobic bacteria that are commonly found in the human gastrointestinal tract. Infections caused by Bacteroidaceae are relatively rare, but can occur in cases of severe trauma, surgery, or compromised immune systems. These infections may include bacteremia (bacteria in the blood), abscesses, and wound infections. Treatment typically involves the use of antibiotics that are effective against anaerobic bacteria. It is important to note that proper identification of the specific species causing the infection is necessary for appropriate treatment, as different species within Bacteroidaceae may have different susceptibilities to various antibiotics.

"Porphyromonas gingivalis" is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found in the oral cavity and is associated with periodontal disease. It is a major pathogen in chronic periodontitis, which is a severe form of gum disease that can lead to destruction of the tissues supporting the teeth, including the gums, periodontal ligament, and alveolar bone.

The bacterium produces several virulence factors, such as proteases and endotoxins, which contribute to its pathogenicity. It has been shown to evade the host's immune response and cause tissue destruction through various mechanisms, including inducing the production of pro-inflammatory cytokines and matrix metalloproteinases.

P. gingivalis has also been linked to several systemic diseases, such as atherosclerosis, rheumatoid arthritis, and Alzheimer's disease, although the exact mechanisms of these associations are not fully understood. Effective oral hygiene practices, including regular brushing, flossing, and professional dental cleanings, can help prevent the overgrowth of P. gingivalis and reduce the risk of periodontal disease.

I'm not aware of a medical definition for "DMF Index." The abbreviation "DMF" could potentially stand for many things, as it is used in various contexts across different fields. In the field of dentistry, DMF stands for Decayed, Missing, and Filled teeth/surfaces, which is a method for measuring dental caries or tooth decay. However, there is no standard medical definition for "DMF Index." If you could provide more context or specify the field of study or practice, I would be happy to help further!

A "premature infant" is a newborn delivered before 37 weeks of gestation. They are at greater risk for various health complications and medical conditions compared to full-term infants, due to their immature organ systems and lower birth weight. Some common diseases and health issues that premature infants may face include:

1. Respiratory Distress Syndrome (RDS): A lung disorder caused by the lack of surfactant, a substance that helps keep the lungs inflated. Premature infants, especially those born before 34 weeks, are at higher risk for RDS.
2. Intraventricular Hemorrhage (IVH): Bleeding in the brain's ventricles, which can lead to developmental delays or neurological issues. The risk of IVH is inversely proportional to gestational age, meaning that the earlier the infant is born, the higher the risk.
3. Necrotizing Enterocolitis (NEC): A gastrointestinal disease where the intestinal tissue becomes inflamed and can die. Premature infants are at greater risk for NEC due to their immature digestive systems.
4. Jaundice: A yellowing of the skin and eyes caused by an accumulation of bilirubin, a waste product from broken-down red blood cells. Premature infants may have higher rates of jaundice due to their liver's immaturity.
5. Infections: Premature infants are more susceptible to infections because of their underdeveloped immune systems. Common sources of infection include the mother's genital tract, bloodstream, or hospital environment.
6. Anemia: A condition characterized by a low red blood cell count or insufficient hemoglobin. Premature infants may develop anemia due to frequent blood sampling, rapid growth, or inadequate erythropoietin production.
7. Retinopathy of Prematurity (ROP): An eye disorder affecting premature infants, where abnormal blood vessel growth occurs in the retina. Severe ROP can lead to vision loss or blindness if not treated promptly.
8. Developmental Delays: Premature infants are at risk for developmental delays due to their immature nervous systems and environmental factors such as sensory deprivation or separation from parents.
9. Patent Ductus Arteriosus (PDA): A congenital heart defect where the ductus arteriosus, a blood vessel that connects two major arteries in the fetal heart, fails to close after birth. Premature infants are at higher risk for PDA due to their immature cardiovascular systems.
10. Hypothermia: Premature infants have difficulty maintaining body temperature and are at risk for hypothermia, which can lead to increased metabolic demands, poor feeding, and infection.

A fatal outcome is a term used in medical context to describe a situation where a disease, injury, or illness results in the death of an individual. It is the most severe and unfortunate possible outcome of any medical condition, and is often used as a measure of the severity and prognosis of various diseases and injuries. In clinical trials and research, fatal outcome may be used as an endpoint to evaluate the effectiveness and safety of different treatments or interventions.

Root planing is a dental procedure that involves the cleaning and smoothing of the root surfaces of teeth. It is typically performed as a part of periodontal therapy to treat and manage gum disease. The goal of root planing is to remove tartar, calculus, and bacterial toxins from the roots of teeth, which helps to promote the reattachment of the gums to the teeth and prevent further progression of periodontal disease. This procedure is usually performed under local anesthesia and may require multiple appointments depending on the severity of the case.

Dental caries, also known as tooth decay or cavities, refers to the damage or breakdown of the hard tissues of the teeth (enamel, dentin, and cementum) due to the activity of acid-producing bacteria. These bacteria ferment sugars from food and drinks, producing acids that dissolve and weaken the tooth structure, leading to cavities.

The process of dental caries development involves several stages:

1. Demineralization: The acidic environment created by bacterial activity causes minerals (calcium and phosphate) to be lost from the tooth surface, making it weaker and more susceptible to decay.
2. Formation of a white spot lesion: As demineralization progresses, a chalky white area appears on the tooth surface, indicating early caries development.
3. Cavity formation: If left untreated, the demineralization process continues, leading to the breakdown and loss of tooth structure, resulting in a cavity or hole in the tooth.
4. Infection and pulp involvement: As the decay progresses deeper into the tooth, it can reach the dental pulp (the soft tissue containing nerves and blood vessels), causing infection, inflammation, and potentially leading to toothache, abscess, or even tooth loss.

Preventing dental caries involves maintaining good oral hygiene, reducing sugar intake, using fluoride toothpaste and mouthwash, and having regular dental check-ups and cleanings. Early detection and treatment of dental caries can help prevent further progression and more severe complications.

Shiitake mushrooms (Lentinula edodes) are not a medical term, but rather a type of edible mushroom that is commonly used in cooking and has been studied for potential medicinal properties. Here's a brief description:

Shiitake mushrooms are native to East Asia and are widely cultivated and consumed in many countries, including Japan, China, and Korea. They have a distinctive brown cap, a firm texture, and a rich, earthy flavor. Shiitake mushrooms contain various bioactive compounds, such as polysaccharides, terpenoids, and sterols, which are believed to contribute to their potential health benefits. Some of the reported medicinal properties include immunomodulatory, antitumor, antiviral, antibacterial, and anti-inflammatory effects. However, more research is needed to confirm these findings and establish the optimal dosage and safety profiles for different applications.

It's important to note that while shiitake mushrooms can be a healthy addition to a balanced diet, they should not be used as a substitute for medical treatment or professional advice. Always consult with a healthcare provider for any health concerns or conditions.

Microbial consortia refer to a group or community of microorganisms, including bacteria, archaea, fungi, and viruses, that naturally exist together in a specific environment and interact with each other. These interactions can be synergistic, where the organisms benefit from each other's presence, or competitive, where they compete for resources.

Microbial consortia play important roles in various biological processes, such as biogeochemical cycling, plant growth promotion, and wastewater treatment. The study of microbial consortia is essential to understanding the complex interactions between microorganisms and their environment, and has implications for fields such as medicine, agriculture, and environmental science.

Orthodontic appliances are devices used in orthodontics, a branch of dentistry focused on the diagnosis, prevention, and treatment of dental and facial irregularities. These appliances can be fixed or removable and are used to align teeth, correct jaw relationships, or modify dental forces. They can include braces, aligners, palatal expanders, space maintainers, and headgear, among others. The specific type of appliance used depends on the individual patient's needs and the treatment plan developed by the orthodontist.

Bacteroides are a genus of gram-negative, anaerobic, rod-shaped bacteria that are normally present in the human gastrointestinal tract. They are part of the normal gut microbiota and play an important role in breaking down complex carbohydrates and other substances in the gut. However, some species of Bacteroides can cause opportunistic infections, particularly in individuals with weakened immune systems or when they spread to other parts of the body. They are resistant to many commonly used antibiotics, making infections caused by these bacteria difficult to treat.

Chlorhexidine is an antimicrobial agent used for its broad-spectrum germicidal properties. It is effective against bacteria, viruses, and fungi. It is commonly used as a surgical scrub, hand sanitizer, and healthcare disinfectant. Chlorhexidine is available in various forms, including solutions, gels, and sprays. It works by disrupting the microbial cell membrane, leading to the death of the organism. It is also used in mouthwashes and skin cleansers for its antimicrobial effects.

Factor XIIIa is a protein involved in the blood clotting process. It is a activated form of Factor XIII, which is a protransglutaminase enzyme that plays a role in stabilizing blood clots. Factor XIIIa cross-links fibrin molecules in the clot to form a more stable and insoluble clot. This action helps prevent further bleeding from the site of injury.

Factor XIIIa is formed when thrombin, another protein involved in blood clotting, cleaves and activates Factor XIII. Once activated, Factor XIIIa catalyzes the formation of covalent bonds between fibrin molecules, creating a mesh-like structure that strengthens the clot.

Deficiencies or dysfunctions in Factor XIIIa can lead to bleeding disorders, including factor XIII deficiency, which is a rare but serious condition characterized by prolonged bleeding and an increased risk of spontaneous hemorrhage.

In medical terms, the mouth is officially referred to as the oral cavity. It is the first part of the digestive tract and includes several structures: the lips, vestibule (the space enclosed by the lips and teeth), teeth, gingiva (gums), hard and soft palate, tongue, floor of the mouth, and salivary glands. The mouth is responsible for several functions including speaking, swallowing, breathing, and eating, as it is the initial point of ingestion where food is broken down through mechanical and chemical processes, beginning the digestive process.

The periodontium is a complex structure in the oral cavity that surrounds and supports the teeth. It consists of four main components:
1. Gingiva (gums): The pink, soft tissue that covers the crown of the tooth and extends down to the neck of the tooth, where it meets the cementum.
2. Cementum: A specialized, calcified tissue that covers the root of the tooth and provides a surface for the periodontal ligament fibers to attach.
3. Periodontal ligament (PDL): A highly vascular and cell-rich connective tissue that attaches the cementum of the tooth root to the alveolar bone, allowing for tooth mobility and absorption of forces during chewing.
4. Alveolar bone: The portion of the jawbone that contains the sockets (alveoli) for the teeth. It is a spongy bone with a rich blood supply that responds to mechanical stresses from biting and chewing, undergoing remodeling throughout life.

Periodontal diseases, such as gingivitis and periodontitis, affect the health and integrity of the periodontium, leading to inflammation, bleeding, pocket formation, bone loss, and ultimately tooth loss if left untreated.

'Commiphora' is a genus of shrubs and trees in the family Burseraceae, commonly known as myrrh trees. They are native to dry regions of Africa and Arabia. The bark and resin of several species have been used traditionally for medicinal purposes, such as treating wounds, skin infections, and digestive disorders. Myrrh oil is also used in aromatherapy and as a flavoring agent in foods and beverages. Some studies suggest that myrrh extracts may have anti-inflammatory, antimicrobial, and antioxidant properties, but more research is needed to confirm these effects and determine their safety and efficacy.

Staphylococcal pneumonia is a type of pneumonia caused by the bacterium Staphylococcus aureus. This bacteria can colonize the upper respiratory tract and sometimes invade the lower respiratory tract, causing pneumonia.

The symptoms of staphylococcal pneumonia are often severe and may include fever, cough, chest pain, shortness of breath, and production of purulent sputum. The disease can progress rapidly, leading to complications such as pleural effusion (accumulation of fluid in the space surrounding the lungs), empyema (pus in the pleural space), and bacteremia (bacteria in the bloodstream).

Staphylococcal pneumonia can occur in otherwise healthy individuals, but it is more common in people with underlying medical conditions such as chronic lung disease, diabetes, or a weakened immune system. It can also occur in healthcare settings, where S. aureus may be transmitted from person to person or through contaminated equipment.

Treatment of staphylococcal pneumonia typically involves the use of antibiotics that are active against S. aureus, such as nafcillin or vancomycin. In some cases, surgery may be necessary to drain fluid from the pleural space.

Sodium bicarbonate, also known as baking soda, is a chemical compound with the formula NaHCO3. It is a white solid that is crystalline but often appears as a fine powder. It has a slightly salty, alkaline taste and is commonly used in cooking as a leavening agent.

In a medical context, sodium bicarbonate is used as a medication to treat conditions caused by high levels of acid in the body, such as metabolic acidosis. It works by neutralizing the acid and turning it into a harmless salt and water. Sodium bicarbonate can be given intravenously or orally, depending on the severity of the condition being treated.

It is important to note that sodium bicarbonate should only be used under the supervision of a healthcare professional, as it can have serious side effects if not used properly. These may include fluid buildup in the body, electrolyte imbalances, and an increased risk of infection.

Veillonellaceae is a family of Gram-negative, anaerobic bacteria found in various environments, including the human mouth and gut. The bacteria are known for their ability to produce acetic and lactic acid as end products of their metabolism. They are often part of the normal microbiota of the body, but they can also be associated with certain infections, particularly in individuals with weakened immune systems.

It's important to note that while Veillonellaceae bacteria are generally considered to be commensal organisms, meaning they exist harmoniously with their human hosts, they have been implicated in some disease states, such as periodontitis (gum disease) and bacterial pneumonia. However, more research is needed to fully understand the role of these bacteria in health and disease.

Also acute necrotizing ulcerative gingivitis and necrotizing ulcerative periodontitis, it is a type of periodontal disease ... Necrotizing periodontal diseases Necrotizing gingivitis Necrotizing periodontitis Necrotizing stomatitis Periodontitis as ... Dufty, J; Gkranias, N; Donos, N (2017). "Necrotising Ulcerative Gingivitis: A Literature Review". Oral Health & Preventive ... Gingivitis is typically painless and is most commonly a result of plaque biofilm accumulation, in association with reduced or ...
Treatment includes steroid gel and analgesics (anesthetic suspension). Mucocele Acute necrotizing ulcerative gingivitis List of ... Angina bullosa haemorrhagica does not cause desquamative gingivitis. ...
It is often used in the short term to treat acute necrotising ulcerative gingivitis. Side effects can occur with prolonged use ... It is not suited for use in acute necrotizing ulcerative gingivitis, however. Rinsing with chlorhexidine mouthwash before and ... The proportion of Gram-negative rods increase as gingivitis develops, so it is also used to reduce gingivitis. It is sometimes ... The first known references to mouth rinsing is in Ayurveda for treatment of gingivitis. Later, in the Greek and Roman periods, ...
... "necrotizing ulcerative periodontitis". The "ulcerative" descriptor was removed from the name, because ulceration is considered ... Necrotizing gingivitis is part of a spectrum of disease termed necrotizing periodontal diseases. It is the most minor form of ... along with necrotizing periodontitis (NP) and necrotizing stomatitis, is classified as a necrotizing periodontal disease, one ... Necrotizing gingivitis (NG) is a common, non-contagious infection of the gums with sudden onset. The main features are painful ...
The milder form, necrotizing ulcerative gingivitis (also termed "trench mouth"), is characterized by painful, bleeding gums and ... Necrotizing ulcerative periodontitis (NUP) is where the infection leads to attachment loss, and involves only the gingiva, ... This condition can develop into necrotizing ulcerative periodontitis. Histoplasma capsulatum is the causative organism in ... While in some individuals gingivitis never progresses to periodontitis, periodontitis is always preceded by gingivitis. In 1976 ...
Vincent's gingivitis is usually termed necrotizing ulcerative gingivitis (sometimes known as trench mouth). He is also ... When the gums are involved, it was termed "Vincent's gingivitis". In modern times, ...
However, an acute form of gingivitis/periodontitis, termed acute necrotizing ulcerative gingivitis (ANUG), can develop, often ... acute necrotizing ulcerative gingivitis (a gum infection), and temporomandibular disorder. Pulpitis is reversible when the pain ... Common marginal gingivitis in response to subgingival plaque is usually a painless condition. ... 299 conditions which cause gingivostomatitis and desquamative gingivitis. Various conditions may involve the alveolar bone, and ...
There have been many reported cases occurring in Africa which are coexistent with acute necrotizing ulcerative gingivitis or ...
... the soft tissue around the crown of the involved tooth may show a similar appearance to necrotizing ulcerative gingivitis. ...
It is known to play a pathogenic role in necrotizing ulcerative gingivitis and necrotizing ulcerative periodontitis, worsening ...
This condition can develop into necrotizing ulcerative periodontitis. This is an uncommon form of chronic (more than one month ... This is a localized or generalized, linear band of erythematous gingivitis (inflammation of the gums). It was first observed in ... HIV infected individuals and termed "HIV-gingivitis", but the condition is not confined to this group. Candida species are ...
... acute necrotizing ulcerative gingivitis and adult periodontitis. Together with Porphyromonas gingivalis they are known as black ... P. intermedia and P. nigrescens are associated with inflammatory periodontal diseases, such as pregnancy gingivitis, ...
and anaerobic spirochetes are often the cause of acute necrotizing ulcerative gingivitis (or Vincent's angina) which is a ... Deeper anaerobic soft-tissue infections are necrotizing fasciitis, necrotizing synergistic cellulitis, gas gangrene and ... distinct form of ulcerative gingivitis. Deep neck infections that develop as a consequence of oral, dental and pharyngeal ... Progression of the infection from pneumonitis into necrotizing pneumonia and pulmonary abscess can occur, with or without the ...
Acute necrotizing ulcerative gingivitis, also known as "trench mouth"-another painful, non-contagious mouth infection with ... but also inflammatory bowel disease such as Crohn's disease or ulcerative colitis. The link between gastrointestinal disorders ...
Other possible risk factors include periodontal disease, acute necrotizing ulcerative gingivitis, local bone disease, Paget's ... such as necrotizing ulcerative gingivitis or chronic periodontitis. Wisdom teeth not associated with pericoronitis are less ...
... acute necrotizing ulcerative gingivitis, and pericoronitis. A periapical abscess responds well to antibiotics if chewing gum is ... In the UK, it has effective use in dentistry as it is the primary drug prescribed for acute ulcerative gingivitis. It is also ...
Guidelines for National Unification between mainland China and Taiwan Necrotizing ulcerative gingivitis, a subclassification of ... the Necrotizing periodontal diseases This disambiguation page lists articles associated with the title NUG. If an internal link ...
Scurvy (lack of dietary vitamin C) Acute necrotizing ulcerative gingivitis Abnormal tooth position, such as tooth crowding, ... Cavities below the gum line If the gum recession is caused by gingivitis, the following symptoms may also be present: Puffy, ... it is the treatment of gingivitis that reveals a gum recession problem, that was previously masked by the gums swelling. ...
... including gingivitis and periodontitis, and often found in acute necrotizing ulcerative gingivitis. It is commonly isolated ...
Acute necrotizing ulcerative stomatitis, gingivitis or periodontitis Conditions where confirmatory diagnostic testing is ...
... periodontitis Aggressive periodontitis Periodontitis as a manifestation of systemic disease Necrotizing ulcerative gingivitis/ ... Periodontitis Necrotizing periodontal diseases Necrotizing Gingivitis Necrotizing periodontitis Necrotizing stomatitis ... In its early stage, called gingivitis, the gums become swollen and red and may bleed. It is considered the main cause of tooth ... In some people, gingivitis progresses to periodontitis - with the destruction of the gingival fibers, the gum tissues separate ...
... gingivitis MeSH C07.465.714.258.480.360 - gingival pocket MeSH C07.465.714.258.480.446 - gingivitis, necrotizing ulcerative ... necrotizing MeSH C07.465.815.815 - sialorrhea MeSH C07.465.815.882 - submandibular gland diseases MeSH C07.465.815.882.500 - ...
... necrotizing gingivitis, phagedenic gingivitis, trench mouth, ulcerative gingivitis, Vincent gingivitis, Vincent infection, ... Acute necrotizing ulcerative gingivitis (acute membranous gingivitis, acute necrotizing ulcerative gingivostomatitis, ... Acne aestivalis (Mallorca acne) Acne conglobata Acne cosmetica (cosmetic acne) Acne fulminans (acute febrile ulcerative acne) ... Cyclic neutropenia Desquamative gingivitis Drug-induced ulcer of the lip Epidermization of the lip Epulis Epulis fissuratum ( ...
... is widely confused with necrotizing ulcerative gingivitis (previously also called "Vincent's gingivitis"), ... symptoms of necrotizing ulcerative gingivitis, such as painful gums may also be present. The tonsils show single or multiple ... Taylor, FE; McKinstry, WH (1917). "The Relation of Peri-dental Gingivitis to Vincent's Angina". Proceedings of the Royal ... Later in 1904, Vincent described the same pathogenic organisms in "ulceronecrotic gingivitis". As a result, ...
... gingivitis, necrotizing ulcerative MeSH C01.252.400.388.750 - rat-bite fever MeSH C01.252.400.466 - helicobacter infections ... necrotizing MeSH C01.252.410.890.485 - impetigo MeSH C01.252.410.890.670 - pneumococcal infections MeSH C01.252.410.890.670.595 ...
... necrotising ulcerative gingivitis, and early tooth loss, especially in the lower front teeth. While plaque and poor oral ... People with Down syndrome tend to be more susceptible to gingivitis as well as early, severe periodontal disease, ...
HSV can apply sunscreen lip balm as ultraviolet light is a stimulus for the infection Acute necrotizing ulcerative gingivitis " ... Gingivostomatitis is a combination of gingivitis and stomatitis, or an inflammation of the oral mucosa and gingiva. Herpetic ...
... acute necrotizing ulcerative gingivitis Trench (surname) includes list of people with the name Trench, Telford, Shropshire, ...
... secondary Acute myelomonocytic leukemia Acute necrotizing ulcerative gingivitis Acute non lymphoblastic leukemia (generic term ...
... is sometimes used as a synonym of the necrotizing periodontal disease more commonly termed necrotizing ulcerative gingivitis, ... Cheilitis, glossitis, gingivitis syndrome; atypical gingivostomatitis, plasma-cell gingivitis, plasmacytosis of gingiva". Oral ... or a more severe form (also termed necrotizing stomatitis). The term necrotizing gingivostomatitis is also sometimes used. Also ... Plasma cell gingivitis may also occur, which may be accompanied by glossitis and cheilitis. Allergens that may cause allergic ...
Empiric therapeutic regimens for acute necrotizing ulcerative gingivitis (ANUG) are outlined below, including those for ... encoded search term (Acute Necrotizing Ulcerative Gingivitis Empiric Therapy) and Acute Necrotizing Ulcerative Gingivitis ... The phylum Synergistetes in gingivitis and necrotizing ulcerative gingivitis. J Med Microbiol. 2012 Nov. 61:1600-9. [QxMD ... Acute Necrotizing Ulcerative Gingivitis Empiric Therapy Updated: Dec 09, 2019 * Author: James M Stephen, MD, FAAEM, FACEP; ...
Acute necrotizing ulcerative gingivitis: risk factors involving host defense mechanisms. Download Prime PubMed App to iPhone, ... Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment.. *Necrotizing ulcerative gingivitis, ... Holistic care concepts, bruxism and necrotizing ulcerative gingivitis.. *Acute necrotizing ulcerative gingivitis-periodontitis ... Acute necrotizing ulcerative gingivitis: clinical features, etiology and treatment.. *[Current aspects of necrotizing ...
Acute Necrotizing Ulcerative Gingivitis (ANUG) - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the ... Acute Necrotizing Ulcerative Gingivitis (ANUG) (Fusospirochetosis; Trench Mouth; Vincent Infection or Vincent Angina). By ... Acute necrotizing ulcerative gingivitis is a painful infection of the gums. Symptoms are acute pain, bleeding, and foul breath ... Acute necrotizing ulcerative gingivitis (ANUG) occurs most frequently in smokers and debilitated patients who are under stress ...
Acute necrotizing ulcerative gingivitis (ANUG), also known as trench mouth, is a type of infection of the gums.[1] It results ... necrotizing stomatitis, and the most extreme, cancrum oris. Acute necrotizing ulcerative gingivitis (ANUG) refers to the ... Acute necrotizing ulcerative gingivitis is rare.[1] The condition has been known since the 4th century BCE.[1][2] Modern ... Necrotizing ulcerative gingivitis has been observed for centuries. Xenophon observes sore mouth and foul smelling breath in ...
HomeMiscellaneousNecrotizing Ulcerative Gingivitis - Vincents angina. Necrotizing Ulcerative Gingivitis - Vincents angina. ...
acute cecrotizing ulcerative gingivitis. ♦ What is acute necrotizing ulcerative gingivitis?. A progressive painful disease of ... Acute necrotizing ulcerative gingivitis (ANUG; colloquially known as trench mouth). Is a common, non-contagious infection of ... Necrotizing ulcerative gingivitis has been observed for centuries. Xenophon observes sore mouth and foul smelling breath in ... Acute necrotizing ulcerative gingivitis_Plaut-Vincent. synonymous:. • trench mouth. • Plaut-Vincent. • Vincents angina. • ...
... www.dynamed.com/condition/acute-necrotizing-ulcerative-gingivitis. *Acute necrotizing ulcerative gingivitis. Merck Manual ... Acute necrotizing ulcerative gingivitis (ANUG) is a serious infection of the gums. ... www.merckmanuals.com/professional/dental-disorders/periodontal-disorders/acute-necrotizing-ulcerative-gingivitis-anug. ... Acute necrotizing ulcerative gingivitis. EBSCO DynaMed website. Available at: https:// ...
Acute Necrotizing Ulcerative Gingivitis (ANUG) - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD ... Acute Necrotizing Ulcerative Gingivitis (ANUG) (Fusospirochetosis; Trench Mouth; Vincent Infection or Vincent Angina). By ... Acute necrotizing ulcerative gingivitis is a painful infection of the gums. Symptoms are acute pain, bleeding, and foul breath ... Acute necrotizing ulcerative gingivitis (ANUG) occurs most frequently in smokers and debilitated patients who are under stress ...
Acute Necrotizing Ulcerative Gingivitis. (ANUG; Trench Mouth; Vincents Stomatitis). by Cynthia M. Johnson, MA ... Acute necrotizing ulcerative gingivitis (ANUG) is a serious infection of the gums. ... www.merckmanuals.com/professional/dental-disorders/periodontal-disorders/acute-necrotizing-ulcerative-gingivitis-anug. Accessed ... www.dynamed.com/condition/acute-necrotizing-ulcerative-gingivitis. Accessed August 16, 2021. ...
Necrotizing ulcerative gingivitis, better known as trench mouth, is an acute gingival infection caused by bacterial plaque. ... Trench Mouth (Necrotizing Ulcerative Gingivitis). Dental professionals worldwide continuously stress the importance of ...
Acute necrotizing ulcerative gingivitis (ANUG) is a liberal transmission with ulceration, swelling and sloughing away of asleep ... Complete Information on Acute necrotizing ulcerative gingivitis with Treatment and Prevention. 25th June 2008 ...
Acute necrotizing ulcerative gingivitis (ANUG). *Acute necrotizing ulcerative mucositis. *Gastroesophageal reflux disease (GERD ...
In rare cases, a person with gum disease may experience a painful gum infection called acute necrotizing ulcerative gingivitis ... Atout R. N., & Todescan, S. (2013). Managing Patients with necrotizing ulcerative gingivitis.. http://www.jcda.ca/article/d46. ... found that a mouthwash containing extracts of clove, basil, and tea tree oil demonstrated anti-plaque and anti-gingivitis ... In this study, participants with gingivitis chewed either a green tea chewing gum or a placebo chewing gum for 15 minutes per ...
Acute Necrotizing Ulcerative Gingivitis. Aaron SL, DeBlois KW. Aaron SL, et al. 2023 Jul 20. In: StatPearls [Internet]. ...
Also acute necrotizing ulcerative gingivitis and necrotizing ulcerative periodontitis, it is a type of periodontal disease ... Necrotizing periodontal diseases Necrotizing gingivitis Necrotizing periodontitis Necrotizing stomatitis Periodontitis as ... Dufty, J; Gkranias, N; Donos, N (2017). "Necrotising Ulcerative Gingivitis: A Literature Review". Oral Health & Preventive ... Gingivitis is typically painless and is most commonly a result of plaque biofilm accumulation, in association with reduced or ...
Gingivitis has been classified by clinical appearance (eg, ulcerative, hemorrhagic, necrotizing, purulent), etiology (eg, drug- ... Gingivitis is an inflammatory process limited to the mucosal epithelial tissue surrounding the cervical portion of the teeth ... Acute necrotizing ulcerative gingivitis. Acute necrotizing infection may occur as a complication of chronic gingivitis in ... Acute necrotizing ulcerative gingivitis (ANUG, ie, trench mouth) is an acute infectious gingivitis. The term trench mouth was ...
Acute necrotizing ulcerative gingivitis. *Deciduous dentition. *Buccal, lingual, distal, mesial, occlusal. *Mucocele ...
Categories: Gingivitis, Necrotizing Ulcerative Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Acute necrotizing ulcerative gingivitis (ANUG). *Acute necrotizing ulcerative mucositis. *Gastroesophageal reflux disease (GERD ...
... it resembles acute necrotizing ulcerative gingivitis Acute Necrotizing Ulcerative Gingivitis (ANUG) Acute necrotizing ... Periodontitis usually develops when gingivitis Gingivitis Gingivitis is a type of periodontal disease characterized by ... Ninety percent of patients with necrotizing ulcerative periodontitis due to HIV (HIV-associated periodontitis) respond to ... Necrotizing periodontitis Necrotizing periodontitis is a particularly virulent, rapidly progressing disease characterized by ...
Gingival and Periodontal Diseases: Conditions such as necrotizing ulcerative gingivitis (NUG) is prevalent in smokers. ...
Acute Necrotizing Ulcerative Gingivitis: A New Complication of Mumps. Batool Sharifi-Mood , Minoo Mohraz , Seyed-Dawood ...
Gingivitis is a common and mild form of gum disease that causes irritation, redness and swelling of your gums. ... Trench mouth, also known as necrotizing ulcerative gingivitis (NUG), is a severe form of gingivitis that causes painful, ... Gingivitis Enlarge image Close Gingivitis. Gingivitis. Gingivitis can cause dusky red, swollen, tender gums that bleed easily, ... Gingivitis is common, and anyone can develop it. Factors that can increase your risk of gingivitis include:. *Poor oral care ...
Gingivitis may progress to periodontal disease, and this can lead to the serious condition acute necrotising ulcerative ... Acute necrotising ulcerative gingivitis is a painful bacterial infection of the gums associated with marked swelling and ... Some cases require direct referral to an appropriate specialist, and this would include acute necrotising ulcerative gingivitis ... 2. Gingivitis and periodontitis. Gingivitis is usually caused by a build up of plaque on the teeth. Adequate brushing usually ...
acute necrotizing ulcerative gingivitis (급성 괴사성 궤양성 치은염) erosive-ulcerative (미란 궤양성의) erosive-ulcerative lesion (미란 궤양성 병소) ... erosive-ulcerative nature (미란 궤양성) necrotizing ulcerative (괴사 궤양성) ulcerative (궤양성) ulcerative carcinoma (궤양성 암종) ulcerative ... 괴사성 궤양성 (급성) 치은염(Necrotizing ulcerative (acute) gingivitis) 괴사성 궤양성 (급성) 치은구내염(Necrotizing ulcerative (acute) gingivostomatitis ... ulcerative colitis (궤양성 대장염, 궤양성 장염) ulcerative genital change (생식기의 궤양성 변화) ulcerative genital lesion (생식기의 궤양성 병소) ulcerative ...
... acute necrotizing ulcerative gingivitis, a painful, fast-moving, noncontagious infection by mostly anaerobic bacteria, ... Lang N, Soskolne WA, Greenstein G, Cochran D, Corbet E, Meng HX, et al. Consensus report: necrotizing periodontal diseases. Ann ...
... necrotizing ulcerative gingivitis), dermatologic conditions (lichen planus, cicatricial pemphigoid, pemphigus), and traumatic ... However, halitosis and necrotic, exudative, or bleeding gums may be present with the following: (1) necrotizing ulcerative ... Sharon-Buller A, Sela M. CO2-laser treatment of ulcerative lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Mar ... GI disorders, such as regional enteropathy (Crohn disease), ulcerative colitis, and celiac disease (gluten-sensitive ...
if acute necrotising ulcerative gingivitis *commence metronidazole (adult dose 400mg tds for 5 days) and refer to dentist for ... gingivitis Last reviewed 01/2018. Gingivitis is superficial gum inflammation recognised by the increased redness of the gums ...
... or acute necrotizing ulcerative gingivitis.. Uh, I think Id rather have something like "Sweet syndrome", or, even better, " ... or acute necrotizing ulcerative gingivitis.. Uh, I think Id rather have something like "Sweet syndrome", or, even better, " ...
Acute Necrotising Ulcerative Gingivitis (ANUG) [1]. Adolescents [2]. Adults [2]. AIDS (Disease) [1]. ...
  • Acute necrotizing ulcerative gingivitis (ANUG) occurs most frequently in smokers and debilitated patients who are under stress. (merckmanuals.com)
  • • ANUG is the acute presentation of necrotizing ulcerative gingivitis (NUG), which is the usual course the disease takes. (microbe-canvas.com)
  • Available at: https://www.merckmanuals.com/professional/dental-disorders/periodontal-disorders/acute-necrotizing-ulcerative-gingivitis-anug. (cvs.com)
  • Acute necrotizing ulcerative gingivitis (ANUG) is a liberal transmission with ulceration, swelling and sloughing away of asleep tissue from the lip and throat payable to the spreading of transmission from the gums. (articlealley.com)
  • Untreated ANUG can progress to NUP (necrotizing ulcerative periodontitis), in which there is bone loss around the teeth and eventually tooth loss. (morenovalleycosmeticdentist.com)
  • As a type of gum disease there is acute necrotizing ulcerative gingivitis (Anug) which people genetically inherit. (erdemdental.com)
  • Acute stress, suppression of the immune system, proper and inadequate nutrition, excessive smoking and existing gingivitis are among the factors that lead to the development and progression of ANUG. (erdemdental.com)
  • ANUG is a rare type of gingivitis that is caused by excessive smoking. (drgrubb.com)
  • Two bacteria are commonly seen together in acute necrotizing ulcerative gingivitis (ANUG), a serious periodontal disease. (freezingblue.com)
  • Acute necrotizing ulcerative gingivitis (ANUG, ie, trench mouth) is an acute infectious gingivitis. (medscape.com)
  • This disease, along with necrotizing (ulcerative) periodontitis ( NP or NUP ) is classified as a necrotizing periodontal disease , one of the seven general types of periodontitis . (microbe-canvas.com)
  • Similar features but with more intense pain may be seen in necrotizing periodontitis in HIV/AIDS. (microbe-canvas.com)
  • In periodontitis, deep pockets form in the periodontal tissue and can harbor anaerobic organisms that do more damage than those usually present in simple gingivitis. (merckmanuals.com)
  • In developmental or acquired deformities and conditions , faulty occlusion, causing an excessive functional load on teeth, plus the requisite plaque and gingivitis may contribute to progression of a particular type of periodontitis characterized by angular bony defects. (merckmanuals.com)
  • Necrotizing periodontitis typically occurs in patients with an impaired immune system and thus is often called HIV-associated periodontitis because HIV is a common cause. (merckmanuals.com)
  • The GP can help patients by giving advice and treatment for gingivitis and periodontitis. (gponline.com)
  • As opposed to gingivitis or periodontitis, which are chronic infections, these conditions can be associated with pain or discomfort, and may have immediate systemic manifestations. (morenovalleycosmeticdentist.com)
  • If your gingivitis is left untreated, the condition progresses to periodontitis, which is when the infection moves under your gums and into the bone underneath. (erdemdental.com)
  • Periodontitis, unlike gingivitis, it is an inflammatory disease that causes damage to the root of the tooth, the bone, surrounding the tooth root, and the connective tissue between these two tissues. (erdemdental.com)
  • The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS , marginal PERIODONTITIS , injury, and ASCORBIC ACID DEFICIENCY. (lookformedical.com)
  • Gingivitis may progress to periodontal disease, and this can lead to the serious condition acute necrotising ulcerative gingivitis (sometimes referred to as Vincent's angina or trench mouth). (gponline.com)
  • Untreated, the infection may lead to rapid destruction of the periodontium and can spread, as necrotizing stomatitis or noma, into neighbouring tissues in the cheeks, lips or the bones of the jaw. (microbe-canvas.com)
  • Seventeen new cases of chronic ulcerative stomatitis with literature review. (mhmedical.com)
  • Ulcers may appear as single or multiple lesions, and they are easily distinguished from primary or secondary viral infections, bacterial infections (eg, necrotizing ulcerative gingivitis), dermatologic conditions (lichen planus, cicatricial pemphigoid, pemphigus), and traumatic injuries (contusions, lacerations, burns) by the healthy appearance of adjacent tissues and the lack of distinguishing systemic features. (medscape.com)
  • This bacterium is a common commensal in the gingival crevice and is often isolated from cases of gingivitis and other purulent lesions related to the mouth . (lookformedical.com)
  • Gingivitis proceeds through an initial stage to produce early lesions, which then progress to advanced disease. (medscape.com)
  • when it comes the differential diagnosis of the disease with gingivitis experts define it by pain, necrosis of the gingival papilla between the two teeth, and bleeding. (erdemdental.com)
  • Acute necrotizing ulcerative gingivitis is a painful infection of the gums. (merckmanuals.com)
  • Gingivitis Gingivitis is a type of periodontal disease characterized by inflammation of the gums (gingivae), causing bleeding with swelling, redness, exudate, a change of normal contours, and, occasionally. (merckmanuals.com)
  • Bleeding or swollen gums may mean nothing more than over-zealous brushing or gingivitis, or more seriously, a bleeding diathesis or leukaemia. (gponline.com)
  • Acute necrotising ulcerative gingivitis is a painful bacterial infection of the gums associated with marked swelling and ulceration of the mucosa. (gponline.com)
  • Gingivitis is superficial gum inflammation recognised by the increased redness of the gums and bleeding on brushing. (gpnotebook.com)
  • Gingivitis is the mildest form of gum disease, which means you have an infection in your gums. (erdemdental.com)
  • Ulcerative - refers to the fact that with this condition ulcers and sores often appear on the gums. (periodontaldiseasetreatment.org)
  • Gingivitis - "gingiva" is another word for your gums and "gingivitis" refers to a bacterial infection of the gingiva, or gum tissue. (periodontaldiseasetreatment.org)
  • The researchers concluded that chewing green tea gum may help treat gum inflammation when used in combination with other gingivitis treatments. (medicalnewstoday.com)
  • Inflammation of the mucous membrane, which affects deeper layers than ulcerative colitis, is likely to spread to other areas if a hole is pierced through the barrier. (pe.kr)
  • A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. (edu.au)
  • Necrotizing ulcerative gingivitis, often caused by an infection with both spirochetes and fusiform bacilli, is common in young adults under stress (classically in students at examination time). (mhmedical.com)
  • Some cases require direct referral to an appropriate specialist, and this would include acute necrotising ulcerative gingivitis, unexplained tooth mobility for more than three weeks, unexplained ulceration of the oral mucosa or mass persisting for more than three weeks, and suspected lichen planus or leukoplakia. (gponline.com)
  • The most common type of gingivitis is a chronic form induced by plaque. (medscape.com)
  • Moderate chronic gingivitis. (medscape.com)
  • In recent years, periodontal disease, the endpoint of chronic gingivitis, slowly has decreased among adult Americans. (medscape.com)
  • Patients who have gingivitis and build-up of plaque will benefit from regular dental advice, and they should be encouraged to see their dentist. (gponline.com)
  • A good dental and oral care with the advices of your dentist will assist you to fastly get rid of the gingivitis. (erdemdental.com)
  • The most common type of gingivitis involves the marginal gingiva and is brought on by the accumulation of microbial plaques in persons with inadequate oral hygiene. (medscape.com)
  • This kind of gingivitis treatment is generally with supra and subgingival tooth cleaning, mouthwash, use of antibiotics and B vitamins. (erdemdental.com)
  • Other conditions contribute to colonization of periodontal pathogens such as mouth breathing, tooth morphology and acute necrotizing ulcerative gingivitis. (bvsalud.org)
  • Necrotizing ulcerative gingivitis is a rare disease, a study by Dufty et al finding, for example, a prevalence of 0.11% in the British armed forces. (medscape.com)
  • Dufty J, Gkranias N, Petrie A, McCormick R, Elmer T, Donos N. Prevalence and treatment of necrotizing ulcerative gingivitis (NUG) in the British Armed Forces: a case-control study. (medscape.com)
  • Necrotising Ulcerative Gingivitis: A Literature Review. (bvsalud.org)
  • In this clinical trial, 136 patients with Crohn's disease and ulcerative colitis were administered Remsima SC and intravenous formulation 'Remsima IV', and then pharmacokinematically confirmed SC non-inferiority compared to IV and compared efficacy and safety for 30 weeks. (pe.kr)
  • As a result of analyzing safety data from a total of 2,800 patients, including 1,800 Crohn's disease and 1,000 ulcerative colitis, the incidence of adverse reactions was similar to that of the original drug. (pe.kr)
  • The number of patients with ulcerative colitis and Crohn's disease in Korea increased by 40% in 5 years from 46,630 in 2013 to 65802 in 2018. (pe.kr)
  • The risk of developing ulcerative colitis in people who smoked more than one pack a day was twice that of non-smokers. (pe.kr)
  • On the other hand, patients with a history of steroid injections, suppository-formulated ulcerative colitis treatments or biological treatments were excluded from this clinical trial. (pe.kr)
  • Ulcerative colitis mainly affects the large intestine, and Crohn's disease spreads widely from the mouth to the anus. (pe.kr)
  • Gingivitis is an inflammatory process limited to the mucosal epithelial tissue surrounding the cervical portion of the teeth and the alveolar processes. (medscape.com)
  • To put it another way, it's more like a severe case of untreated gingivitis. (erdemdental.com)
  • Gingivitis and resulting periodontal disease are seen more frequently in patients with either diabetes or HIV. (medscape.com)
  • Studies in Australia, Sweden, England, and Switzerland report gingivitis in 48-85% of children aged 3-6 years, but whether this range reflects population differences or whether it is due to different criteria used to define the disease is difficult to know. (medscape.com)
  • Gingivitis is usually caused by a build up of plaque on the teeth. (gponline.com)
  • The patient with gingivitis needs advice about good oral hygiene, including brushing the teeth adequately at least twice a day (morning and last thing at night), flossing three times a week or using interdental brushes regularly and stopping smoking if necessary. (gponline.com)
  • A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS . (lookformedical.com)
  • Conditions such as necrotizing ulcerative gingivitis (NUG) is prevalent in smokers. (dentalcare.com)
  • 7] A recent study that induced gingivitis in healthy volunteers was associated with a clear increase in inflammatory markers. (medscape.com)
  • Effect of two new chlorhexidine mouthrinses on the development of dental plaque, gingivitis, and discolouration. (medscape.com)
  • A 2014 study found that a mouthwash containing extracts of clove , basil , and tea tree oil demonstrated anti-plaque and anti-gingivitis properties. (medicalnewstoday.com)
  • Treat acute necrotizing ulcerative gingivitis. (us.com)
  • Many people believe that gingivitis begins in early childhood and that 9-17% of children aged 3-11 years have gingivitis. (medscape.com)