Granulomatous Mastitis
Granuloma
Encyclopedias as Topic
Cystic neutrophilic granulomatous mastitis: an underappreciated pattern strongly associated with gram-positive bacilli. (1/13)
(+info)Idiopathic granulomatous mastitis associated with corynebacterium sp. Infection. (2/13)
Idiopathic granulomatous mastitis (IGM) is a rare inflammatory condition of the breast. The etiology and treatments options of IGM remain controversial. Previous case reports have suggested that Corynebacterium sp., a gram-positive bacillus endogenous to the skin, may be associated with IGM. In the present report, we describe the first case of IGM with a positive culture for Corynebacterium sp. reported in the United States. (+info)Topical steroids to treat granulomatous mastitis: a case report. (3/13)
(+info)Idiopathic granulomatous mastitis associated with risperidone-induced hyperprolactinemia. (4/13)
(+info)Idiopathic granulomatous mastitis: a report of twenty cases. (5/13)
(+info)Recurrent granulomatous mastitis mimicking inflammatory breast cancer. (6/13)
(+info)Idiopathic granulomatous mastitis: rare but important. (7/13)
(+info)Idiopathic granulomatous mastitis: a great imitator? (8/13)
(+info)Granulomatous mastitis is a rare inflammatory condition that affects the breast tissue. It is characterized by the formation of granulomas, which are small collections of immune cells, in the breast. The exact cause of granulomatous mastitis is not fully understood, but it is thought to be related to an abnormal immune response or an infection.
The condition typically affects women of reproductive age and can present with symptoms such as breast pain, swelling, redness, and skin changes. It may also cause the formation of lumps or masses in the breast tissue. In some cases, granulomatous mastitis can be mistaken for breast cancer due to similarities in symptoms and imaging findings.
Diagnosis of granulomatous mastitis typically involves a combination of medical history, physical examination, imaging studies such as mammography or ultrasound, and tissue biopsy. Treatment may include anti-inflammatory medications, antibiotics, or surgical removal of the affected breast tissue. In some cases, corticosteroids or other immunosuppressive drugs may be necessary to manage the condition.
It is important to note that granulomatous mastitis is a rare condition and that most women who experience breast symptoms do not have this condition. If you are concerned about any changes in your breast tissue, it is important to speak with your healthcare provider for further evaluation and appropriate treatment.
Mastitis is a medical condition characterized by inflammation of the breast tissue, usually caused by an infection. It typically occurs in breastfeeding women, when bacteria from the baby's mouth enter the milk ducts through a cracked or damaged nipple, leading to infection and inflammation. However, mastitis can also occur in non-breastfeeding women, often as a result of blocked milk ducts or milk remaining in the breast after weaning.
Symptoms of mastitis may include breast pain, tenderness, swelling, warmth, redness, and fever. In some cases, pus or blood may be present in the breast milk. If left untreated, mastitis can lead to more severe complications such as abscess formation. Treatment typically involves antibiotics to clear the infection, pain relief medication, and continued breastfeeding or pumping to prevent further blockage of the milk ducts.
Corynebacterium infections are caused by bacteria belonging to the genus Corynebacterium, which are gram-positive, rod-shaped organisms that commonly inhabit the skin and mucous membranes of humans and animals. While many species of Corynebacterium are harmless commensals, some can cause a range of infections, particularly in individuals with compromised immune systems or underlying medical conditions.
The most common Corynebacterium species that causes infection is C. diphtheriae, which is responsible for diphtheria, a potentially life-threatening respiratory illness characterized by the formation of a thick, grayish membrane in the throat and upper airways. Other Corynebacterium species, such as C. jeikeium, C. urealyticum, and C. striatum, can cause various types of healthcare-associated infections, including bacteremia, endocarditis, pneumonia, and skin and soft tissue infections.
Corynebacterium infections are typically treated with antibiotics, such as penicillin, erythromycin, or vancomycin, depending on the species of bacteria involved and the patient's medical history. In some cases, surgical intervention may be necessary to drain abscesses or remove infected tissue. Preventive measures, such as vaccination against C. diphtheriae and good hygiene practices, can help reduce the risk of Corynebacterium infections.
A granuloma is a small, nodular inflammatory lesion that occurs in various tissues in response to chronic infection, foreign body reaction, or autoimmune conditions. Histologically, it is characterized by the presence of epithelioid macrophages, which are specialized immune cells with enlarged nuclei and abundant cytoplasm, often arranged in a palisading pattern around a central area containing necrotic debris, microorganisms, or foreign material.
Granulomas can be found in various medical conditions such as tuberculosis, sarcoidosis, fungal infections, and certain autoimmune disorders like Crohn's disease. The formation of granulomas is a complex process involving both innate and adaptive immune responses, which aim to contain and eliminate the offending agent while minimizing tissue damage.
Bovine mastitis is a common inflammatory condition that affects the mammary gland (udder) of dairy cows. It's primarily caused by bacterial infections, with Escherichia coli (E. coli), Streptococcus spp., and Staphylococcus aureus being some of the most common pathogens involved. The infection can lead to varying degrees of inflammation, which might result in decreased milk production, changes in milk composition, and, if left untreated, potentially severe systemic illness in the cow.
The clinical signs of bovine mastitis may include:
- Redness and heat in the affected quarter (or quarters) of the udder
- Swelling and pain upon palpation
- Decreased milk production or changes in milk appearance (such as flakes, clots, or watery consistency)
- Systemic signs like fever, loss of appetite, and depression in severe cases
Mastitis can be classified into two main types: clinical mastitis, which is characterized by visible signs of inflammation, and subclinical mastitis, where the infection might not present with obvious external symptoms but could still lead to decreased milk quality and production.
Prevention and control measures for bovine mastitis include good milking practices, maintaining a clean and dry environment for the cows, practicing proper udder hygiene, administering antibiotics or other treatments as necessary, and regularly monitoring milk for signs of infection through somatic cell count testing.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
A foreign-body reaction is an immune response that occurs when a non-native substance, or "foreign body," is introduced into the human body. This can include things like splinters, surgical implants, or even injected medications. The immune system recognizes these substances as foreign and mounts a response to try to eliminate them.
The initial response to a foreign body is often an acute inflammatory reaction, characterized by the release of chemical mediators that cause vasodilation, increased blood flow, and the migration of white blood cells to the site. This can result in symptoms such as redness, swelling, warmth, and pain.
If the foreign body is not eliminated, a chronic inflammatory response may develop, which can lead to the formation of granulation tissue, fibrosis, and encapsulation of the foreign body. In some cases, this reaction can cause significant tissue damage or impede proper healing.
It's worth noting that not all foreign bodies necessarily elicit a strong immune response. The nature and size of the foreign body, as well as its location in the body, can all influence the severity of the reaction.
Granulomatous mastitis
Mastitis
Nonpuerperal mastitis
Silicone granuloma
Duct ectasia of breast
Sarcoidosis
Paecilomyces variotii
Granulomatous mastitis - Wikipedia
Granulomatous Mastitis: A Therapeutic and Diagnostic Challenge | Breast Care | Karger Publishers
Idiopathic Granulomatous Mastitis (IGM) - Breastfeeding Atlas
Idiopathic granulomatous mastitis: a great imitator?<...
ScholarWorks @ UTRGV - Research Symposium: Granulomatous Mastitis: A rare or an underdiagnosed disease?
Granulomatous Mastitis as a Presentation of Sarcoidosis | SKIN The Journal of Cutaneous Medicine
Clinical experience in the treatment of idiopathic granulomatous mastitis | International Journal of Current Research
Cytological diagnosis of mastitis with emphasis on granulomatous mastitis | International Journal of Current Research
Idiopathic granulomatous mastitis: Diagnostic strategy and therapeutic implications in Omani patients<...
Table - Gordonia sputi Bacteremia - Volume 15, Number 9-September 2009 - Emerging Infectious Diseases journal - CDC
Priscila Fernandes Meireles - Articles - Scientific Research Publishing
Corynebacterium Infections: Background, Pathophysiology, Epidemiology
Magiran | International Journal of Cancer Management، Volume:16 Issue: 1, Dec 2023
suffering - Symptoms, Treatments and Resources for suffering
Gharib M[au] - Search Results - PubMed
Corynebacterium mastitidis: Difference between revisions - microbewiki
On the Case - Radiology Today
Topic Article Package: Cytology | Acta Cytologica | Karger Publishers
EN (en)
Pathology Outlines - Silicone leak / lymphadenopathy
Rev. perú. med. exp. salud publica - vol.27 issue4
Stefania De Sanctis - Articles - Scientific Research Publishing
Image Rendering Techniques in Postmortem Computed Tomography: Evaluation of Biological Health and Profile in Stranded Cetaceans...
Profile | Eurorad
Rachel E. Kaczynski, D.O., FACOS, FSSO | Texas Oncology
Sandia House and Ms. M. - Greater Albuquerque Habitat for Humanity
Axillary Lymphadenopathy - Radiology | UCLA Health
Idiopathic granulomatous22
- Granulomatous mastitis can be divided into idiopathic granulomatous mastitis (also known as granular lobular mastitis) and granulomatous mastitis occurring as a rare secondary complication of a great variety of other conditions such as tuberculosis and other infections, sarcoidosis and granulomatosis with polyangiitis. (wikipedia.org)
- Idiopathic granulomatous mastitis (IGM) is defined as granulomatous mastitis without any other attributable cause such as those above mentioned. (wikipedia.org)
- Treatment is radically different for idiopathic granulomatous mastitis and other granulomatous lesions of the breast, so the precise diagnosis is therefore very important. (wikipedia.org)
- citation needed] Characteristic for idiopathic granulomatous mastitis are multinucleated giant cells and epithelioid histiocytes forming non-caseating granulomas around lobules. (wikipedia.org)
- A literature search in PubMed was performed using the search terms 'granulomatous mastitis', 'idiopathic granulomatous mastitis', 'granulomatous mastitis and immunology', and 'granulomatous mastitis and pathology' for the years 2000-2018. (karger.com)
- Thanks for your inquiry about idiopathic granulomatous mastitis (IGM). (breastfeedingatlas.com)
- Awomolo AM, Louis-Jacques A, Crowe S. Idiopathic granulomatous mastitis diagnosed during pregnancy associated with successful breastfeeding experience. (breastfeedingatlas.com)
- Lei X, Chen K, Zhu L, Song E, Su F, Li S. Treatments for Idiopathic Granulomatous Mastitis: Systematic Review and Meta-Analysis. (breastfeedingatlas.com)
- Idiopathic granulomatous mastitis: a great imitator? (amsterdamumc.org)
- Aetiology of idiopathic granulomatous mastitis. (jofskin.org)
- 4. Fahmy J, Halabi-Tawil M, Bagot M, Tournant B, Petit A. Erythema nodosum during the course of idiopathic granulomatous mastitis. (jofskin.org)
- Background: Idiopathic granulomatous mastitis (IGM) is a rare inflammatory disease of the breast. (journalcra.com)
- In this study, we wanted to share with you our clinical experience in the treatment of idiopathic granulomatous mastitis, which is difficult to diagnose and treat. (journalcra.com)
- Conclusion: We suggest that corticosteroid therapy should be considered as the primary treatment for idiopathic granulomatous mastitis, but it should be considered as the primary treatment in patients with resistant IGM. (journalcra.com)
- While living in the apartment Ms. M was diagnosed with idiopathic granulomatous mastitis. (habitatabq.org)
- An uncommon condition involving the breast is known as Idiopathic granulomatous mastitis ( IGM ), which is considered as an autoimmune benign disorder of the breast that might be mistakenas two common breast disorders, breast carcinoma and breast abscess. (drvikram.com)
- Idiopathic granulomatous mastitis ( IGM ) is non-malignant, chronic inflammatory breast condition. (drvikram.com)
- What could be the Causes of Idiopathic Granulomatous Mastitis? (drvikram.com)
- All properties of is herbs has made it a beneficial Ayurvedic Treatment for Idiopathic Granulomatous Mastitis. (drvikram.com)
- In 16% ( n = 20), no cause could be found and clinical history was consistent with idiopathic granulomatous mastitis. (springer.com)
- The search found records of 42 silicone granulomas, 37 fat necrosis, 20 idiopathic granulomatous mastitis, 14 suture granulomas, 1 Corynebacterium , 1 Mycobacterium fortuitum infection, 2 sarcoidosis and 1 Sjögren's syndrome. (springer.com)
- Nonlactational mastitis may be periductal mastitis, idiopathic granulomatous mastitis, or tuberculous mastitis. (msdmanuals.com)
Abscess1
- The most commonly encountered lesions were acute mastitis or abscess (46%), followed by granulomatous mastitis (36%), followed by tuberculous mastitis (10%), and 6% of acute on chronic mastitis. (journalcra.com)
Lobular2
- Additionally, related Corynebacterium species have been found in granulomatous lobular mastitis in humans [6]. (kenyon.edu)
- Granulomatous Lobular Mastitis is a rather uncommon illness. (netkumar1.co.in)
Inflammation6
- Some cases are due to silicone injection (Silicone-induced granulomatous inflammation) or other foreign body reactions. (wikipedia.org)
- A core needle biopsy of the mass was consistent with granulomatous inflammation. (utrgv.edu)
- Microscopy showed the characteristic pattern of granulomatous inflammation. (elsevierpure.com)
- Mastitis results in the inflammation of the mammary glands, which leads to an increased number of somatic cells within the milk of animals affected by the disease. (kenyon.edu)
- Pathology results from left breast mass ultrasound guided core needle biopsy revealed "noncaseating granulomatous inflammation, favor sarcoidosis. (radiologytoday.net)
- This syndrome is characterised by granulomatous inflammation with multinucleated large cells and epithelioid histiocytes. (netkumar1.co.in)
Diagnosis6
- Different causes of mastitis, and most importantly malignancy, usually have to be excluded before the diagnosis of GM can be considered [ 5 ]. (karger.com)
- Based on presentation, history, and physical examination the differential diagnosis included infectious mastitis, breast cancer, and granulomatous mastitis. (utrgv.edu)
- Results: The mastitis diagnosis of patients with medical treatment given to patients without clinical improvement tru-cut biopsy diagnosis of granulomatous mastitis performed. (journalcra.com)
- Objective: The objective of the study is to evaluate the efficacy of fine needle aspiration cytology in the diagnosis of mastitis and estimate the frequency of lesions diagnosed as tuberculous mastitis solely on FNAC. (journalcra.com)
- From the study it can be concluded that FNAC is an efficient, minimally invasive and cost-effective method in the diagnosis of acute and granulomatous mastitis. (journalcra.com)
- Their clinical and radiological examinations were indeterminate, and a diagnosis of granulomatous mastitis was established only by histopathology. (elsevierpure.com)
Plasma Cell Mastitis2
- Plasma cell mastitis (PCM) is a benign breast disease that is refractory and difficult to cure. (amegroups.org)
- Plasma cell mastitis (PCM) is a tip of nonlactating mastitis with benign pathological characteristics. (amegroups.org)
Tuberculosis1
- The lesion is in some cases very difficult to distinguish from breast cancer and other causes such as infections (tuberculosis, syphilis, corynebacterial infection, mycotic infection), autoimmune diseases (sarcoidosis, granulomatosis with polyangiitis), foreign body reaction and granulomatous reaction in a carcinoma must be excluded. (wikipedia.org)
Infectious mastitis1
- Because the clinical presentation can mimic infectious mastitis or inflammatory carcinoma, the disease course is often protracted. (karger.com)
Granuloma1
- Additionally, nine cases of granulomatous lymphadenitis where found: six of which were secondary to granulomatous causes involving the breast (for example, silicone granuloma), one was idiopathic and one patient was diagnosed with cat-scratch disease. (springer.com)
Lesions2
- Elevated prolactin levels have the direct effects of increasing secretory activity of breast lobules, maintaining tight junctions of the ductal epithelium, preventing involution of the breast gland after weaning and are known to stimulate the immune system, contributing to both physiological and pathological granulomatous lesions and non-caseating granulomas. (wikipedia.org)
- Most common causes of granulomatous lesions of the breast and axilla included silicone granulomas 33% ( n = 42), fat necrosis 29% ( n = 37) and suture granulomas 11% ( n = 14). (springer.com)
Biopsy1
- We summarize here 4 cases of tubercu- raphy results, the patient underwent biopsy lous mastitis presenting to the National Re- with a suspicion of malignancy. (who.int)
Sarcoidosis4
- 10. Joint Statement of the American Thoracic Society (ATS) the European Respiratory Society (ERS) the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. (jofskin.org)
- Sarcoidosis is a multisystemic inflammatory granulomatous disease of unknown etiology. (radiologytoday.net)
- American Thoracic Society, the European Respiratory Society, the World Association of Sarcoidosis and Other Granulomatous Disorders. (radiologytoday.net)
- Other granulomatous aetiologies included granulomatous infections, sarcoidosis and Sjögren's syndrome. (springer.com)
20161
- She reports a similar episode in 2016, after a miscarriage, for which she was diagnosed with mastitis and underwent incision and drainage with subsequent resolution. (utrgv.edu)
Aetiology1
- Fistulas to the skin and nipple retraction can suggest chronicity and a granulomatous aetiology. (springer.com)
Biopsies1
- Biopsies show a granulomatous formation in combination with a localized infiltration of multi-nucleated giant cells, epithelioid histiocytes, and plasma cells. (karger.com)
Chronic inflammatory breast1
- Granulomatous mastitis (GM) is a benign chronic inflammatory breast disease that is poorly understood, with no universal agreement on underlying etiologies and treatment protocol. (utrgv.edu)
Tuberculous1
- Data was collected from the cytology section of the Pathology Department and smears retrieved were reviewed and differentiated as acute, granulomatous or tuberculous mastitis. (journalcra.com)
Disease5
- Similar cases of granulomatous mastitis were reported in IgG4-related disease though the exact relationship to IGM remains to be elucidated. (wikipedia.org)
- Granulomatous mastitis (GM) is a rare benign inflammatory breast disease that affects mostly women of childbearing age with a history of breastfeeding. (karger.com)
- Since granulomatous mastitis (GM) was first described as a benign disease entity in 1972 by Kessler and Wolloch [ 1 ], hundreds of cases have been reported from all over the world. (karger.com)
- Research Symposium: Granulomatous Mastitis: A rare or an underdiagnosed disease? (utrgv.edu)
- 126 women and 1 men) with granulomatous disease of the breast, and their imaging results were available for review by both a fellowship-trained radiologist and breast-imaging consultant radiologist. (springer.com)
20171
- After approval of the Institutional Review Board was obtained, the surgical pathological records from January 2000 to January 2017 were searched for the keyword granulomatous . (springer.com)
Presentation1
- Primary presentation of any of these conditions as mastitis is very rare and in many cases probably predisposed by other breast or systemic conditions. (wikipedia.org)
Lupus1
- Lupus mastitis and antiphospholipid syndrome treated with anticoagulation and immunosuppression: a case report. (uchicago.edu)
Corynebacterium1
- and urinary tract infections and mastitis (affecting milk production) in cattle due to infection with Corynebacterium renale , Corynebacterium cystidis , Corynebacterium pilosum , and Corynebacterium bovis . (medscape.com)
Necrosis1
- a Diagram of a granulomatous response (with central necrosis) to a persisting antigen. (springer.com)
Liver1
- Complete blood count and liver function lomatous mastitis and after ruling out other tests were all normal. (who.int)
Retraction1
- Although we found no laboratory evi- centre with a complaint of breast pain and dence for TB mastitis, due to the Mantoux retraction of the right nipple with yellowish skin test and strong clinical suspicion, the discharge. (who.int)
Malignancy1
- sinus tract also confirmed a granulomatous lesion and there was no sign of malignancy. (who.int)
Diseases1
- This article reviews our experience and describes the literature findings of granulomatous diseases of the breast and axilla. (springer.com)
Rare1
- Granulomatous processes of the breast are rare. (springer.com)
Patients1
- Twenty-two patients with granulomatous mastitis were included in the study. (journalcra.com)
Cases1
- The laboratory is one of the 4 major hist cell mastitis (3 cases) and granulomatous topathology laboratories in Yemen and a mastitis (2 cases). (who.int)
Milk3
- C. mastitidis was first discovered in 1997 after researchers isolated the strain from the milk of sheep infected with subclinical mastitis [4]. (kenyon.edu)
- C. mastitidis was first proposed as a new species in 1997 when strains were isolated in pure culture from the milk of sheep with subclinical mastitis from different geographical regions of Spain [4]. (kenyon.edu)
- The first genome was sequenced using C. mastitidis isolated from the milk of a sheep infected with subclinical mastitis [4]. (kenyon.edu)