Granulomatous Mastitis
Granuloma
Cystic neutrophilic granulomatous mastitis: an underappreciated pattern strongly associated with gram-positive bacilli. (1/13)
(+info)Idiopathic granulomatous mastitis associated with corynebacterium sp. Infection. (2/13)
Idiopathic granulomatous mastitis (IGM) is a rare inflammatory condition of the breast. The etiology and treatments options of IGM remain controversial. Previous case reports have suggested that Corynebacterium sp., a gram-positive bacillus endogenous to the skin, may be associated with IGM. In the present report, we describe the first case of IGM with a positive culture for Corynebacterium sp. reported in the United States. (+info)Topical steroids to treat granulomatous mastitis: a case report. (3/13)
(+info)Idiopathic granulomatous mastitis associated with risperidone-induced hyperprolactinemia. (4/13)
(+info)Idiopathic granulomatous mastitis: a report of twenty cases. (5/13)
(+info)Recurrent granulomatous mastitis mimicking inflammatory breast cancer. (6/13)
(+info)Idiopathic granulomatous mastitis: rare but important. (7/13)
(+info)Idiopathic granulomatous mastitis: a great imitator? (8/13)
(+info)Granulomatous mastitis is a rare inflammatory condition that affects the breast tissue. It is characterized by the formation of granulomas, which are small collections of immune cells, in the breast. The exact cause of granulomatous mastitis is not fully understood, but it is thought to be related to an abnormal immune response or an infection.
The condition typically affects women of reproductive age and can present with symptoms such as breast pain, swelling, redness, and skin changes. It may also cause the formation of lumps or masses in the breast tissue. In some cases, granulomatous mastitis can be mistaken for breast cancer due to similarities in symptoms and imaging findings.
Diagnosis of granulomatous mastitis typically involves a combination of medical history, physical examination, imaging studies such as mammography or ultrasound, and tissue biopsy. Treatment may include anti-inflammatory medications, antibiotics, or surgical removal of the affected breast tissue. In some cases, corticosteroids or other immunosuppressive drugs may be necessary to manage the condition.
It is important to note that granulomatous mastitis is a rare condition and that most women who experience breast symptoms do not have this condition. If you are concerned about any changes in your breast tissue, it is important to speak with your healthcare provider for further evaluation and appropriate treatment.
Mastitis is a medical condition characterized by inflammation of the breast tissue, usually caused by an infection. It typically occurs in breastfeeding women, when bacteria from the baby's mouth enter the milk ducts through a cracked or damaged nipple, leading to infection and inflammation. However, mastitis can also occur in non-breastfeeding women, often as a result of blocked milk ducts or milk remaining in the breast after weaning.
Symptoms of mastitis may include breast pain, tenderness, swelling, warmth, redness, and fever. In some cases, pus or blood may be present in the breast milk. If left untreated, mastitis can lead to more severe complications such as abscess formation. Treatment typically involves antibiotics to clear the infection, pain relief medication, and continued breastfeeding or pumping to prevent further blockage of the milk ducts.
Corynebacterium infections are caused by bacteria belonging to the genus Corynebacterium, which are gram-positive, rod-shaped organisms that commonly inhabit the skin and mucous membranes of humans and animals. While many species of Corynebacterium are harmless commensals, some can cause a range of infections, particularly in individuals with compromised immune systems or underlying medical conditions.
The most common Corynebacterium species that causes infection is C. diphtheriae, which is responsible for diphtheria, a potentially life-threatening respiratory illness characterized by the formation of a thick, grayish membrane in the throat and upper airways. Other Corynebacterium species, such as C. jeikeium, C. urealyticum, and C. striatum, can cause various types of healthcare-associated infections, including bacteremia, endocarditis, pneumonia, and skin and soft tissue infections.
Corynebacterium infections are typically treated with antibiotics, such as penicillin, erythromycin, or vancomycin, depending on the species of bacteria involved and the patient's medical history. In some cases, surgical intervention may be necessary to drain abscesses or remove infected tissue. Preventive measures, such as vaccination against C. diphtheriae and good hygiene practices, can help reduce the risk of Corynebacterium infections.
A granuloma is a small, nodular inflammatory lesion that occurs in various tissues in response to chronic infection, foreign body reaction, or autoimmune conditions. Histologically, it is characterized by the presence of epithelioid macrophages, which are specialized immune cells with enlarged nuclei and abundant cytoplasm, often arranged in a palisading pattern around a central area containing necrotic debris, microorganisms, or foreign material.
Granulomas can be found in various medical conditions such as tuberculosis, sarcoidosis, fungal infections, and certain autoimmune disorders like Crohn's disease. The formation of granulomas is a complex process involving both innate and adaptive immune responses, which aim to contain and eliminate the offending agent while minimizing tissue damage.
Bovine mastitis is a common inflammatory condition that affects the mammary gland (udder) of dairy cows. It's primarily caused by bacterial infections, with Escherichia coli (E. coli), Streptococcus spp., and Staphylococcus aureus being some of the most common pathogens involved. The infection can lead to varying degrees of inflammation, which might result in decreased milk production, changes in milk composition, and, if left untreated, potentially severe systemic illness in the cow.
The clinical signs of bovine mastitis may include:
- Redness and heat in the affected quarter (or quarters) of the udder
- Swelling and pain upon palpation
- Decreased milk production or changes in milk appearance (such as flakes, clots, or watery consistency)
- Systemic signs like fever, loss of appetite, and depression in severe cases
Mastitis can be classified into two main types: clinical mastitis, which is characterized by visible signs of inflammation, and subclinical mastitis, where the infection might not present with obvious external symptoms but could still lead to decreased milk quality and production.
Prevention and control measures for bovine mastitis include good milking practices, maintaining a clean and dry environment for the cows, practicing proper udder hygiene, administering antibiotics or other treatments as necessary, and regularly monitoring milk for signs of infection through somatic cell count testing.
Granulomatous mastitis
Mastitis
Nonpuerperal mastitis
Silicone granuloma
Duct ectasia of breast
Sarcoidosis
Paecilomyces variotii
Granulomatous mastitis - Wikipedia
Cystic Neutrophilic Granulomatous Mastitis
Idiopathic Granulomatous Mastitis in Hispanic Women --- Indiana, 2006--2008
Granulomatous mastitis: the histological differentials | Journal of Clinical Pathology
Mastitis, Breast Abscess, and Granulomatous Mastitis - PubMed
Evaluation of therapeutic mammoplasty techniques in the surgical management of female patients with idiopathic granulomatous...
Granulomatous Mastitis: Part 1 » Crafty Teacher Mama
Granulomatous mastitis, erythema nodosum, and polyarthritis: a case report - Medisys Research
Dx: Idiopathic granulomatous mastitis ➡️median age: 30 yo ➡️usually 2yrs after breast feeding ➡️RF: hyperpro | RheumNow
Table - Gordonia sputi Bacteremia - Volume 15, Number 9-September 2009 - Emerging Infectious Diseases journal - CDC
natural healing - Symptoms, Treatments and Resources for natural healing
Dermis-retained breast dermo-glandular flap: a new surgical approach for granulomatous lobular mastitis. | Front Surg;10:...
The Distribution of Aerobic and Anaerobic Bacteria in the Etiology of Granulomatous Mastitis and Their Resistance to...
Issue August 2021 | Annals Singapore
Pharmacogenetics - Annals Singapore
Corynebacterium Infections Treatment & Management: Medical Care, Surgical Care, Consultations
Why Do Men Have Nipples? 9 FAQs About Lactation, Pain, and More
Biomarkers Search
Rhodococcus equi Infection Differential Diagnoses
Magiran | جستجوی کلیدواژه «Distribution»
Prominent emperipolesis in breast lesion: A diagnostic challenge - CytoJournal
Goshen Health | Find a Doctor | Search for a Medical Provider
Search
For Researchers | Office of Research on Women's Health
Frontiers | MRI-Based Machine Learning in Differentiation Between Benign and Malignant Breast Lesions
Prevalence of Immunosuppressive Drug Use Among Commercially Insured US Adults, 2018-2019 - PubMed
Search
2023 ICD-10-CM Diagnosis Code N61.0: Mastitis without abscess
Idiopathic22
- Granulomatous mastitis can be divided into idiopathic granulomatous mastitis (also known as granular lobular mastitis) and granulomatous mastitis occurring as a rare secondary complication of a great variety of other conditions such as tuberculosis and other infections, sarcoidosis and granulomatosis with polyangiitis. (wikipedia.org)
- Idiopathic granulomatous mastitis (IGM) is defined as granulomatous mastitis without any other attributable cause such as those above mentioned. (wikipedia.org)
- Treatment is radically different for idiopathic granulomatous mastitis and other granulomatous lesions of the breast, so the precise diagnosis is therefore very important. (wikipedia.org)
- citation needed] Characteristic for idiopathic granulomatous mastitis are multinucleated giant cells and epithelioid histiocytes forming non-caseating granulomas around lobules. (wikipedia.org)
- Background The management of granulomatous mastitis depends on the causative factor, and accurate diagnosis in distinguishing between idiopathic granulomatous mastitis (IGM) and tuberculous mastitis (TBM) is indispensable. (bmj.com)
- Also idiopathic granulomatous mastitis, a less common condition, is discussed due to its confusing characteristics and not universally-accepted treatment strategies .Breastfeeding mastitis is inflammation of the breast that can be infectious or non-infectious. (nih.gov)
- Brief Synopsis: I was diagnosed with a somewhat rare condition called idiopathic granulomatous mastitis in August 2018. (craftyteachermama.com)
- Idiopathic granulomatous mastitis (IGM) is a rare, benign, inflammatory breast condition that can cause repeated abscess or mass formation in bilateral breasts. (annals.edu.sg)
- 1. Mammographic and sonographic findings in the diagnosis of idiopathic granulomatous mastitis. (nih.gov)
- 5. Radiologic and clinical features of idiopathic granulomatous lobular mastitis mimicking advanced breast cancer. (nih.gov)
- 6. Multimodality imaging features of idiopathic granulomatous mastitis: outcome of 12 years of experience. (nih.gov)
- 15. Radiologic findings of idiopathic granulomatous mastitis. (nih.gov)
- 16. [Idiopathic granulomatous mastitis: apropos of 8 cases and review of the literature]. (nih.gov)
- 17. Clinical and imaging features of idiopathic granulomatous mastitis - The diagnostic challenges and a brief review. (nih.gov)
- Idiopathic Granulomatous Mastitis as an Unusual Cause of Erythema Nodosum in a Malagasy Woman. (cdc.gov)
- Background: Idiopathic granulomatous mastitis (IGM) is a rare benign breast disease with unknown etiology which can mimic breast carcinoma, both clinically and radiologically. (baskent.edu.tr)
- Background: Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory disease of the breast. (hacettepe.edu.tr)
- A specific type of mastitis called idiopathic granulomatous mastitis causes swelling, pain, redness, and dimpling of the breast skin. (ro.co)
- Is peripheral blood immunophenotyping useful to understand the etiology of Idiopathic Granulomatous? (monocyte.eu)
- BACKGROUND: The etiology of idiopathic granulomatous mastitis (IGM) has not been clearly established. (monocyte.eu)
- Nonlactational mastitis may be periductal mastitis, idiopathic granulomatous mastitis, or tuberculous mastitis. (msdmanuals.com)
- Background and Objectives Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory lesion that<br />mimics the clinical symptoms of carcinoma. (ac.ir)
Lobular mastitis5
- Although granulomatous lobular mastitis is associated with gram-positive bacilli such as Corynebacterium, this association is not well known. (medscape.com)
- Dermis-retained breast dermo-glandular flap: a new surgical approach for granulomatous lobular mastitis. (bvsalud.org)
- Granulomatous lobular mastitis (GLM) is characterized by nonspecific chronic inflammation concentrated in breast lobules. (bvsalud.org)
- 10. Granulomatous lobular mastitis: imaging, diagnosis, and treatment. (nih.gov)
- 11. Granulomatous lobular mastitis: two case reports with focus on radiologic and histopathologic features. (nih.gov)
Abscess2
- It may be due to inflammatory breast disease such as milk stasis or lactational mastitis.In this chapter we discuss the most common complications of breastfeeding including milk stasis, mastitis, and breast abscess. (nih.gov)
- IGM is a recurring inflammatory condition of the breast, often presenting as recurring mastitis, abscess, sinuses and fistulae. (punebreastcare.com)
Diagnosis4
- Cytological diagnosis of granulomatous mastitis is challenging. (cytojournal.com)
- Answer: D. Studies have shown that the presence of neutrophils is an important diagnostic clue in diagnosing granulomatous mastitis, as in the present case, where histocytes showing emperipolesis of neutrophils along with the presence of numerous neutrophils in the background led to the diagnosis in this case. (cytojournal.com)
- These reports showed that TB should always be considered first in the differential diagnosis of granulomatous mastitis in TB-endemic areas. (who.int)
- Join Tami Burdick, a patient advocate and the author of Diagnosis Detective: Curing Granulomatous Mastitis. (libsyn.com)
Tuberculous1
- Are all Granulomatous Mastitis Cases Tuberculous? (turkjpath.org)
Tuberculosis1
- The lesion is in some cases very difficult to distinguish from breast cancer and other causes such as infections (tuberculosis, syphilis, corynebacterial infection, mycotic infection), autoimmune diseases (sarcoidosis, granulomatosis with polyangiitis), foreign body reaction and granulomatous reaction in a carcinoma must be excluded. (wikipedia.org)
Inflammation of the breast1
- Methods The histopathology files from the two participating hospitals were searched for cases of granulomatous inflammation of the breast over an 8-year period. (bmj.com)
Benign4
- Although granulomatous mastitis is easily confused with cancer it is a completely benign (non-cancerous) condition. (wikipedia.org)
- Mastitis-inflammation of breast tissue-is a benign, yet potentially debilitating condition that affects women of childbearing age, and its aetiology is usually infectious or autoimmune. (annals.edu.sg)
- Granulomatous mastitis is a rare benign inflammatory entity described by Kessler and Wolloch in 1972. (cytojournal.com)
- Board certified in general surgery, Dr. O'Neill specializes in breast conservation surgery for breast cancer with an emphasis on cosmetic results, mastectomies, with or without nipple sparing, inoffice core biopsies, SAVI device placement to allow accelerated partial breast irradiation, and benign breast disease, including granulomatous mastitis genetic testing with referrals for further counseling when appropriate. (arizonaoncology.com)
Diagnostic1
- 14. [Sonographic features and diagnostic analysis of breast granulomatous diseases: a report of 32 cases]. (nih.gov)
Lesion1
- sinus tract also confirmed a granulomatous lesion and there was no sign of malignancy. (who.int)
Chronic inflammatory1
- Objective: Granulomatous mastitis (GM) is a rare chronic inflammatory disease of the breast. (bezmialem.edu.tr)
Antibiotics2
- In another review of antimicrobial treatment options for corynebacterial mastitis, Corynebacterium kroppenstedtii was susceptible to most antibiotics except beta lactams, while Corynebacterium tuberculostearicum was resistant to most antibiotics. (medscape.com)
- In such cases, if there is no treatment with antibiotics, one-third of them can develop mastitis. (draliozluk.com)
Infections1
- Other things that can cause peau d'orange include infections, mastitis (breast tissue inflammation), and changes in the fat composition of the breast. (ro.co)
Redness1
- Symptoms of mastitis can include fevers, redness, warmth and pain. (punebreastcare.com)
Epithelioid1
- Cytological features of granulomatous mastitis include the presence of epithelioid cell granulomas, multinucleated giant cells, histiocytes with phagocytosed neutrophils, and numerous neutrophils. (cytojournal.com)
Granulomas1
- Elevated prolactin levels have the direct effects of increasing secretory activity of breast lobules, maintaining tight junctions of the ductal epithelium, preventing involution of the breast gland after weaning and are known to stimulate the immune system, contributing to both physiological and pathological granulomatous lesions and non-caseating granulomas. (wikipedia.org)
Findings3
Disease2
- Similar cases of granulomatous mastitis were reported in IgG4-related disease though the exact relationship to IGM remains to be elucidated. (wikipedia.org)
- This could provide minor evidence to suggest that IGM is an autoimmune granulomatous disease with a local course. (monocyte.eu)
Liver1
- Complete blood count and liver function lomatous mastitis and after ruling out other tests were all normal. (who.int)
Treatment1
- [ 7 ] Clarithryomycin has also been used for treatment of granulomatous mastitis, although typically therapy must be continued for months. (medscape.com)
Patients1
- 7. Imaging features of granulomatous mastitis in 36 patients with new sonographic signs. (nih.gov)
Typically1
- Unlike traditional mastitis, which is associated with breastfeeding, the cause is typically unknown. (ro.co)
Nipple1
- Although we found no laboratory evi- centre with a complaint of breast pain and dence for TB mastitis, due to the Mantoux retraction of the right nipple with yellowish skin test and strong clinical suspicion, the discharge. (who.int)
Cases8
- Some cases are due to silicone injection (Silicone-induced granulomatous inflammation) or other foreign body reactions. (wikipedia.org)
- Primary presentation of any of these conditions as mastitis is very rare and in many cases probably predisposed by other breast or systemic conditions. (wikipedia.org)
- We report 3 cases of mastitis caused by gram-positive bacilli. (medscape.com)
- Two cases were also granulomatous. (medscape.com)
- Most cases were granulomatous, but all cases had a suppurative component with distinct vacuoles that were thought to represent dissolved lipid. (medscape.com)
- This is particularly problematic in the cases of granulomatous mastitis in which the microbiological studies are negative. (bmj.com)
- We summarize here 4 cases of tubercu- raphy results, the patient underwent biopsy lous mastitis presenting to the National Re- with a suspicion of malignancy. (who.int)
- The laboratory is one of the 4 major hist cell mastitis (3 cases) and granulomatous topathology laboratories in Yemen and a mastitis (2 cases). (who.int)
Milk1
- When an infection in the breast is deeper than the skin and reaches the milk ducts and glands, it's know as mastitis. (ro.co)
Type2
- The etiological role of bacteria in granulomatous mastitis, which is the most common type of non-lactational mastitis, is not exactly known. (bezmialem.edu.tr)
- Another type of chronic granulomatous mastitis is immunological<br />mastitis, which is related to the infiltration of IgG4 plasma cells. (ac.ir)
Painful1
- Digital dermatitis presents in a variety of stages ranging from painful, bright red, ulcerated skin lesions to less painful, gray-black, circular, granulomatous skin lesions. (msdvetmanual.com)
Breast pain1
- In addition to cancer surgeries, she is also an expert in granulomatous mastitis, giant fibroadenomas, breast pain, small breast problems, and breast reduction surgeries. (theentrepreneurbytes.com)
Common1
- Mastitis or infection of breast tissue, is common during breastfeeding. (punebreastcare.com)
Case report1
- Rhodococcus equi granulomatous mastitis in an immuno-competent patient - A case report. (medscape.com)