Hemangiosarcoma
Dog Diseases
Lymphangiosarcoma
Hemosiderin
Hemangioma
Ethylene Glycols
Dogs
Neoplasms, Vascular Tissue
Hemosiderosis
Histiocytic Disorders, Malignant
Carcinogenicity Tests
Cat Diseases
Fatal Outcome
Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. (1/508)
Angiosarcomas apparently derive from blood vessel endothelial cells; however, occasionally their histological features suggest mixed origin from blood and lymphatic endothelia. In the absence of specific positive markers for lymphatic endothelia the precise distinction between these components has not been possible. Here we provide evidence by light and electron microscopic immunohistochemistry that podoplanin, a approximately 38-kd membrane glycoprotein of podocytes, is specifically expressed in the endothelium of lymphatic capillaries, but not in the blood vasculature. In normal skin and kidney, podoplanin colocalized with vascular endothelial growth factor receptor-3, the only other lymphatic marker presently available. Complementary immunostaining of blood vessels was obtained with established endothelial markers (CD31, CD34, factor VIII-related antigen, and Ulex europaeus I lectin) as well as podocalyxin, another podocytic protein that is also localized in endothelia of blood vessels. Podoplanin specifically immunolabeled endothelia of benign tumorous lesions of undisputed lymphatic origin (lymphangiomas, hygromas) and was detected there as a 38-kd protein by immunoblotting. As paradigms of malignant vascular tumors, poorly differentiated (G3) common angiosarcomas (n = 8), epitheloid angiosarcomas (n = 3), and intestinal Kaposi's sarcomas (n = 5) were examined for their podoplanin content in relation to conventional endothelial markers. The relative number of tumor cells expressing podoplanin was estimated and, although the number of cases in this preliminary study was limited to 16, an apparent spectrum of podoplanin expression emerged that can be divided into a low-expression group in which 0-10% of tumor cells contained podoplanin, a moderate-expression group with 30-60% and a high-expression group with 70-100%. Ten of eleven angiosarcomas and all Kaposi's sarcomas showed mixed expression of both lymphatic and blood vascular endothelial phenotypes. By double labeling, most podoplanin-positive tumor cells coexpressed endothelial markers of blood vessels, whereas few tumor cells were positive for individual markers only. From these results we conclude that (1) podoplanin is a selective marker of lymphatic endothelium; (2) G3 angiosarcomas display a quantitative spectrum of podoplanin-expressing tumor cells; (3) in most angiosarcomas, a varying subset of tumor cells coexpresses podoplanin and endothelial markers of blood vessels; and (4) all endothelial cells of Kaposi's sarcomas expressed the lymphatic marker podoplanin. (+info)Vaginal epithelioid angiosarcoma. (2/508)
A case of epithelioid angiosarcoma of the vagina is described. Only five cases of angiosarcoma at this site have been reported, three of which followed radiotherapy for other gynaecological malignancies. None is described as an epithelioid angiosarcoma, an unusual and recently described variant which is readily confused with carcinoma. This is thought to be the first reported epithelioid angiosarcoma at this site and highlights the difficulties in diagnosis. (+info)Primary right atrial angiosarcoma mimicking acute pericarditis, pulmonary embolism, and tricuspid stenosis. (3/508)
A 29 year old white man presented to the emergency room with new onset pleuritic chest pain and shortness of breath. He was initially diagnosed as having viral pericarditis and was treated with non-steroidal anti-inflammatory drugs. A few weeks later he developed recurrent chest pain with cough and haemoptysis. Chest radiography, cardiac examination, transthoracic and transoesophageal echocardiography pointed to a mass that arose from the posterior wall of the right atrium, not attached to the interatrial septum, which protruded into the lumen of the right atrium causing intermittent obstruction of inflow across the tricuspid valve. Contrast computed tomography of the chest showed a right atrial mass extending to the anterior chest wall. The lung fields were studded with numerous pulmonary nodules suggestive of metastases. A fine needle aspiration of the pulmonary nodule revealed histopathology consistent with spindle cell sarcoma thought to originate in the right atrium. Immunohistochemical stains confirmed that this was an angiosarcoma. There was no evidence of extracardiac origin of the tumour. The patient was treated with chemotherapy and radiation. This case highlights the clinical presentation, rapid and aggressive course of cardiac angiosarcomas, and the diagnostic modalities available for accurate diagnosis. (+info)Primary cardiac Kaposi's sarcoma. (4/508)
We report the clinical, laboratory, and necropsy findings in a 14-year-old boy with a primary Kaposi's sarcoma of the heart. Primary cardiac Kaposi's sarcoma and angiosarcoma are compared, and the pathogenesis of Kaposi's sarcoma is discussed. Relevant literature is briefly reviewed. (+info)Biological effects of vinyl chloride: an experimental study. (5/508)
Plasma activities of alkaline phosphatase, (AP), transaminases and total lactate dehydrogenase (LDH) with isoenzymes were determined in mice inhaling 50 and 550 ppm vinyl chloride (VC). The animals were also autopsied and the tissue pathology was studies. The total LDH activity was elevanted in both dose groups along with a shift to cathodic enzymes. AP was increased in animals exposed to 500 ppm and transaminases were not at all changed. Enzyme changes occurred after the appearance of tumors. Alveologenic adenomas occurred in all animals at the higher dosage and in about half of the animals inhaling the lower dose. Subperitoneal and subcutaneous hemangiosarcomas were frequent in both dose groups; but especially among 50 ppm animals. Only one animal had a hemangiosarcoma of the liver. No liver fibrosis was seen. All primary subperitoneal and subcutaneous tumors were located in fat tissue. Telangiectasis was observed in two animals in the 500 ppm series. The importance of blood vessel changes in the toxicology of vinyl chloride is discussed. (+info)Case report: spontaneous hemangiosarcoma in the pancreas of a Fischer rat. (6/508)
Spontaneous hemangioma or hemangiosarcoma is sometimes found in the viscera and soft tissue of rats and mice. However, there is no report of the tumor occurring in the pancreas of rats. We report a pancreatic hemangiosarcoma in a 109-wk-old, male Fischer 344 rat, which was used in the control group of a carcinogenicity study. The tumor destroyed and compressed the normal pancreatic tissue and displayed a high density in terms of the numerous capillaries and strands of endothelial tumor cells. A reticulin stain revealed a dense network formation. The frequency of proliferating cell nuclear antigen-positive staining showed active proliferation of the tumor cells. Immunohistochemically, some of the tumor cells stained positive with factor VIII-related antigen, and ultrastructurally, Weibel-Palade bodies were rarely observed in the cytoplasm of the tumor cell. From these findings, the tumor was diagnosed as a hemangiosarcoma that occurred naturally in the pancreas. (+info)The risk of angiosarcoma following primary breast cancer. (7/508)
Lymphangiosarcoma of the upper extremity is a rare and aggressive tumour reported to occur following post-mastectomy lymphoedema (Stewart-Treves syndrome). Haemangiosarcoma, a related rare tumour, has occasionally been reported to occur in the breast following irradiation. We conducted a case-control study using the University of Southern California-Cancer Surveillance Program, the population-based cancer registry for Los Angeles County, to evaluate the relationship between invasive female breast cancer and subsequent upper extremity or chest lymphangiosarcoma and haemangiosarcoma together referred to as angiosarcoma. Cases were females diagnosed between 1972 and 1995 with angiosarcoma of the upper extremity (n = 20) or chest (n = 48) who were 25 years of age or older and residing in Los Angeles County when diagnosed. Other sarcomas at the same anatomic sites were also studied. Controls were females diagnosed with cancers other than sarcoma during the same time period (n = 266,444). Cases and controls were then compared with respect to history of a prior invasive epithelial breast cancer. A history of breast cancer increased the risk of upper extremity angiosarcoma by more than 59-fold (odds ratio [OR] = 59.3, 95% confidence interval [95% CI] = 21.9-152.8). A strong increase in risk after breast cancer was also observed for angiosarcoma of the chest and breast (OR = 11.6, 95% CI = 4.3-26.1) and for other sarcomas of the chest and breast (OR = 3.3, 95% CI = 1.1-1.7). (+info)Primary cardiac angiosarcoma associated with cardiac tamponade: case report. (8/508)
A 57-year-old male with primary cardiac angiosarcoma was initially admitted for cardiac tamponade. Pericardiocentesis was performed twice preoperatively, but the bloody pericardial fluid was cytologically negative for malignant cells. The tumor in the right atrium was resected during cardiopulmonary bypass. The resected tumor was 5.5x4.5x3.0cm in size and the diagnosis of cardiac angiosarcoma was made histologically. There were no tumor cells in the surgical margin. Unfortunately the patient died 3.5 months after surgery due to multiple recurrence in the pericardium. A suitable therapy for cardiac angiosarcoma is still controversial, but early antemortem diagnosis and more aggressive combined treatment should be considered. (+info)Hemangiosarcoma is a type of cancer that arises from the cells that line the blood vessels (endothelial cells). It most commonly affects middle-aged to older dogs, but it can also occur in cats and other animals, as well as rarely in humans.
This cancer can develop in various parts of the body, including the skin, heart, spleen, liver, and lungs. Hemangiosarcomas of the skin tend to be more benign and have a better prognosis than those that arise internally.
Hemangiosarcomas are highly invasive and often metastasize (spread) to other organs, making them difficult to treat. The exact cause of hemangiosarcoma is not known, but exposure to certain chemicals, radiation, and viruses may increase the risk of developing this cancer. Treatment options typically include surgery, chemotherapy, and/or radiation therapy, depending on the location and stage of the tumor.
There is no medical definition for "dog diseases" as it is too broad a term. However, dogs can suffer from various health conditions and illnesses that are specific to their species or similar to those found in humans. Some common categories of dog diseases include:
1. Infectious Diseases: These are caused by viruses, bacteria, fungi, or parasites. Examples include distemper, parvovirus, kennel cough, Lyme disease, and heartworms.
2. Hereditary/Genetic Disorders: Some dogs may inherit certain genetic disorders from their parents. Examples include hip dysplasia, elbow dysplasia, progressive retinal atrophy (PRA), and degenerative myelopathy.
3. Age-Related Diseases: As dogs age, they become more susceptible to various health issues. Common age-related diseases in dogs include arthritis, dental disease, cancer, and cognitive dysfunction syndrome (CDS).
4. Nutritional Disorders: Malnutrition or improper feeding can lead to various health problems in dogs. Examples include obesity, malnutrition, and vitamin deficiencies.
5. Environmental Diseases: These are caused by exposure to environmental factors such as toxins, allergens, or extreme temperatures. Examples include heatstroke, frostbite, and toxicities from ingesting harmful substances.
6. Neurological Disorders: Dogs can suffer from various neurological conditions that affect their nervous system. Examples include epilepsy, intervertebral disc disease (IVDD), and vestibular disease.
7. Behavioral Disorders: Some dogs may develop behavioral issues due to various factors such as anxiety, fear, or aggression. Examples include separation anxiety, noise phobias, and resource guarding.
It's important to note that regular veterinary care, proper nutrition, exercise, and preventative measures can help reduce the risk of many dog diseases.
Splenic neoplasms refer to abnormal growths or tumors in the spleen, which can be benign (non-cancerous) or malignant (cancerous). These growths can arise from various cell types present within the spleen, including hematopoietic cells (red and white blood cells, platelets), stromal cells (supporting tissue), or lymphoid cells (part of the immune system).
There are several types of splenic neoplasms:
1. Hematologic malignancies: These are cancers that affect the blood and bone marrow, such as leukemias, lymphomas, and multiple myeloma. They often involve the spleen, causing enlargement (splenomegaly) and neoplastic infiltration of splenic tissue.
2. Primary splenic tumors: These are rare and include benign lesions like hemangiomas, lymphangiomas, and hamartomas, as well as malignant tumors such as angiosarcoma, littoral cell angiosarcoma, and primary splenic lymphoma.
3. Metastatic splenic tumors: These occur when cancer cells from other primary sites spread (metastasize) to the spleen. Common sources of metastasis include lung, breast, colon, and ovarian cancers, as well as melanomas and sarcomas.
Symptoms of splenic neoplasms may vary depending on the type and extent of the disease but often include abdominal pain or discomfort, fatigue, weight loss, and anemia. Diagnosis typically involves imaging studies (such as ultrasound, CT, or MRI scans) and sometimes requires a biopsy for confirmation. Treatment options depend on the type of neoplasm and may include surgery, chemotherapy, radiation therapy, targeted therapy, or immunotherapy.
Lymphangiosarcoma is a rare and aggressive type of soft tissue cancer that originates from the lymphatic vessels. It primarily affects the skin, particularly in patients who have had long-standing lymphedema (chronic swelling of a body part due to lymph fluid accumulation). The condition is also known as Stewart-Treves syndrome when it occurs in the upper limb of postmastectomy lymphedematous extremities.
Lymphangiosarcoma is characterized by the proliferation of malignant cells within the walls of the lymphatic vessels, leading to the formation of tumors that can ulcerate and bleed. The cancer can metastasize (spread) to other parts of the body, such as the lungs and liver, making it a serious and life-threatening condition.
The diagnosis of lymphangiosarcoma typically involves a combination of clinical examination, imaging studies, and biopsy. Treatment usually includes surgical resection of the tumor, followed by radiation therapy and chemotherapy to reduce the risk of recurrence and metastasis. However, due to its rarity and aggressiveness, lymphangiosarcoma has a poor prognosis, with a low survival rate.
Hemosiderin is a golden-brown pigment that consists of iron-containing protein complexes called ferritin and ferrikinase. It is insoluble in water and forms as a result of the breakdown of hemoglobin in the reticuloendothelial system, primarily in macrophages. Hemosiderin deposits can be found in various tissues and organs, such as the spleen, liver, and brain, under conditions of increased red blood cell destruction or impaired iron metabolism. These deposits are often associated with diseases such as hemochromatosis, thalassemia, and chronic inflammation.
A hemangioma is a benign (noncancerous) vascular tumor or growth that originates from blood vessels. It is characterized by an overgrowth of endothelial cells, which line the interior surface of blood vessels. Hemangiomas can occur in various parts of the body, but they are most commonly found on the skin and mucous membranes.
Hemangiomas can be classified into two main types:
1. Capillary hemangioma (also known as strawberry hemangioma): This type is more common and typically appears during the first few weeks of life. It grows rapidly for several months before gradually involuting (or shrinking) on its own, usually within the first 5 years of life. Capillary hemangiomas can be superficial, appearing as a bright red, raised lesion on the skin, or deep, forming a bluish, compressible mass beneath the skin.
2. Cavernous hemangioma: This type is less common and typically appears during infancy or early childhood. It consists of large, dilated blood vessels and can occur in various organs, including the skin, liver, brain, and gastrointestinal tract. Cavernous hemangiomas on the skin appear as a rubbery, bluish mass that does not typically involute like capillary hemangiomas.
Most hemangiomas do not require treatment, especially if they are small and not causing any significant problems. However, in cases where hemangiomas interfere with vital functions, impair vision or hearing, or become infected, various treatments may be considered, such as medication (e.g., corticosteroids, propranolol), laser therapy, surgical excision, or embolization.
Ethylene glycols are a class of synthetic chemical compounds that are commonly used as automotive antifreeze, de-icing agents, and as raw materials in the manufacture of polyester fibers and resins. The two most common types of ethylene glycol are ethylene glycol monoethyl ether (also known as ethylene glycol monomethyl ether or EGME) and diethylene glycol (DEG).
Ethylene glycols are colorless, odorless liquids with a sweet taste. They are highly toxic to humans and animals if ingested, inhaled, or absorbed through the skin. Exposure can cause a range of symptoms, including nausea, vomiting, abdominal pain, dizziness, confusion, seizures, coma, and even death.
In medical terms, ethylene glycols are often referred to as "toxic alcohols" or "antifreeze poisoning" when they cause toxicity in humans. Treatment typically involves supportive care, such as fluid replacement and kidney dialysis, as well as the use of specific antidotes, such as fomepizole or ethanol, to prevent further absorption and metabolism of the toxic alcohol.
I believe there might be a misunderstanding in your question. "Dogs" is not a medical term or condition. It is the common name for a domesticated carnivore of the family Canidae, specifically the genus Canis, which includes wolves, foxes, and other extant and extinct species of mammals. Dogs are often kept as pets and companions, and they have been bred in a wide variety of forms and sizes for different purposes, such as hunting, herding, guarding, assisting police and military forces, and providing companionship and emotional support.
If you meant to ask about a specific medical condition or term related to dogs, please provide more context so I can give you an accurate answer.
A neoplasm of vascular tissue is an abnormal growth or mass of cells in the blood vessels or lymphatic vessels. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms, such as hemangiomas and lymphangiomas, are typically not harmful and may not require treatment. However, they can cause symptoms if they grow large enough to press on nearby organs or tissues. Malignant neoplasms, such as angiosarcomas, are cancerous and can invade and destroy surrounding tissue, as well as spread (metastasize) to other parts of the body. Treatment for vascular tissue neoplasms depends on the type, size, location, and stage of the growth, and may include surgery, radiation therapy, chemotherapy, or a combination of these.
Hemosiderosis is a medical condition characterized by the abnormal accumulation of hemosiderin, an iron-containing protein, in various organs and tissues of the body. Hemosiderin is derived from the breakdown of hemoglobin, which is the oxygen-carrying protein in red blood cells. When there is excessive breakdown of red blood cells or impaired clearance of hemosiderin, it can lead to its accumulation in organs such as the liver, spleen, and lungs.
Hemosiderosis can be classified into two types: primary and secondary. Primary hemosiderosis is a rare condition that is caused by genetic disorders affecting red blood cells, while secondary hemosiderosis is more common and is associated with various conditions that cause excessive breakdown of red blood cells or chronic inflammation. These conditions include hemolytic anemias, repeated blood transfusions, liver diseases, infections, and certain autoimmune disorders.
The accumulation of hemosiderin can lead to tissue damage and organ dysfunction, particularly in the lungs, where it can cause pulmonary fibrosis, and in the heart, where it can lead to heart failure. Hemosiderosis is typically diagnosed through a combination of medical history, physical examination, and laboratory tests, including blood tests and imaging studies such as chest X-rays or MRI scans. Treatment of hemosiderosis depends on the underlying cause and may include medications, blood transfusions, or supportive care to manage symptoms and prevent complications.
Malignant histiocytic disorders are a group of rare and aggressive cancers that affect the mononuclear phagocyte system, which includes histiocytes or cells that originate from bone marrow precursors called monoblasts. These disorders are characterized by the uncontrolled proliferation of malignant histiocytes, leading to tissue invasion and damage.
There are several types of malignant histiocytic disorders, including:
1. Acute Monocytic Leukemia (AML-M5): This is a subtype of acute myeloid leukemia that affects the monocyte cell lineage and can involve the skin, lymph nodes, and other organs.
2. Langerhans Cell Histiocytosis (LCH): Although primarily considered a benign histiocytic disorder, some cases of LCH can progress to a malignant form with aggressive behavior and poor prognosis.
3. Malignant Histiocytosis (MH): This is a rare and aggressive disorder characterized by the infiltration of malignant histiocytes into various organs, including the liver, spleen, and lymph nodes.
4. Histiocytic Sarcoma (HS): This is a highly aggressive cancer that arises from malignant histiocytes and can affect various organs, such as the skin, lymph nodes, and soft tissues.
Symptoms of malignant histiocytic disorders depend on the type and extent of organ involvement but may include fever, fatigue, weight loss, anemia, and enlarged lymph nodes or organs. Treatment typically involves a combination of chemotherapy, radiation therapy, and/or stem cell transplantation. The prognosis for malignant histiocytic disorders is generally poor, with a high risk of relapse and a low overall survival rate.
Carcinogenicity tests are a type of toxicity test used to determine the potential of a chemical or physical agent to cause cancer. These tests are typically conducted on animals, such as rats or mice, and involve exposing the animals to the agent over a long period of time, often for the majority of their lifespan. The animals are then closely monitored for any signs of tumor development or other indicators of cancer.
The results of carcinogenicity tests can be used by regulatory agencies, such as the U.S. Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA), to help determine safe exposure levels for chemicals and other agents. The tests are also used by industry to assess the potential health risks associated with their products and to develop safer alternatives.
It is important to note that carcinogenicity tests have limitations, including the use of animals, which may not always accurately predict the effects of a chemical on humans. Additionally, these tests can be time-consuming and expensive, which has led to the development of alternative test methods, such as in vitro (test tube) assays and computational models, that aim to provide more efficient and ethical alternatives for carcinogenicity testing.
There are many diseases that can affect cats, and the specific medical definitions for these conditions can be quite detailed and complex. However, here are some common categories of feline diseases and examples of each:
1. Infectious diseases: These are caused by viruses, bacteria, fungi, or parasites. Examples include:
* Feline panleukopenia virus (FPV), also known as feline parvovirus, which can cause severe gastrointestinal symptoms and death in kittens.
* Feline calicivirus (FCV), which can cause upper respiratory symptoms such as sneezing and nasal discharge.
* Feline leukemia virus (FeLV), which can suppress the immune system and lead to a variety of secondary infections and diseases.
* Bacterial infections, such as those caused by Pasteurella multocida or Bartonella henselae, which can cause abscesses or other symptoms.
2. Neoplastic diseases: These are cancerous conditions that can affect various organs and tissues in cats. Examples include:
* Lymphoma, which is a common type of cancer in cats that can affect the lymph nodes, spleen, liver, and other organs.
* Fibrosarcoma, which is a type of soft tissue cancer that can arise from fibrous connective tissue.
* Squamous cell carcinoma, which is a type of skin cancer that can be caused by exposure to sunlight or tobacco smoke.
3. Degenerative diseases: These are conditions that result from the normal wear and tear of aging or other factors. Examples include:
* Osteoarthritis, which is a degenerative joint disease that can cause pain and stiffness in older cats.
* Dental disease, which is a common condition in cats that can lead to tooth loss, gum inflammation, and other problems.
* Heart disease, such as hypertrophic cardiomyopathy (HCM), which is a thickening of the heart muscle that can lead to congestive heart failure.
4. Hereditary diseases: These are conditions that are inherited from a cat's parents and are present at birth or develop early in life. Examples include:
* Polycystic kidney disease (PKD), which is a genetic disorder that causes cysts to form in the kidneys and can lead to kidney failure.
* Hypertrophic cardiomyopathy (HCM), which can be inherited as an autosomal dominant trait in some cats.
* Progressive retinal atrophy (PRA), which is a group of genetic disorders that cause degeneration of the retina and can lead to blindness.
A fatal outcome is a term used in medical context to describe a situation where a disease, injury, or illness results in the death of an individual. It is the most severe and unfortunate possible outcome of any medical condition, and is often used as a measure of the severity and prognosis of various diseases and injuries. In clinical trials and research, fatal outcome may be used as an endpoint to evaluate the effectiveness and safety of different treatments or interventions.
I understand you are asking for a medical definition of "Horse Diseases." However, it's important to note that there isn't a specific medical field dedicated to horse diseases as we typically categorize medical fields by human diseases and conditions. Veterinary medicine is the field responsible for studying, diagnosing, and treating diseases in animals, including horses.
Here's a general definition of 'Horse Diseases':
Horse diseases are health issues or medical conditions that affect equine species, particularly horses. These diseases can be caused by various factors such as bacterial, viral, fungal, or parasitic infections; genetic predispositions; environmental factors; and metabolic disorders. Examples of horse diseases include Strangles (Streptococcus equi), Equine Influenza, Equine Herpesvirus, West Nile Virus, Rabies, Potomac Horse Fever, Lyme Disease, and internal or external parasites like worms and ticks. Additionally, horses can suffer from musculoskeletal disorders such as arthritis, laminitis, and various injuries. Regular veterinary care, preventative measures, and proper management are crucial for maintaining horse health and preventing diseases.
Carcinogens are agents (substances or mixtures of substances) that can cause cancer. They may be naturally occurring or man-made. Carcinogens can increase the risk of cancer by altering cellular DNA, disrupting cellular function, or promoting cell growth. Examples of carcinogens include certain chemicals found in tobacco smoke, asbestos, UV radiation from the sun, and some viruses.
It's important to note that not all exposures to carcinogens will result in cancer, and the risk typically depends on factors such as the level and duration of exposure, individual genetic susceptibility, and lifestyle choices. The International Agency for Research on Cancer (IARC) classifies carcinogens into different groups based on the strength of evidence linking them to cancer:
Group 1: Carcinogenic to humans
Group 2A: Probably carcinogenic to humans
Group 2B: Possibly carcinogenic to humans
Group 3: Not classifiable as to its carcinogenicity to humans
Group 4: Probably not carcinogenic to humans
This information is based on medical research and may be subject to change as new studies become available. Always consult a healthcare professional for medical advice.
Hemangiosarcoma
Yunnan Baiyao
Liver disease
Jake (rescue dog)
Hemothorax
Liver cancer
Lymphangiosarcoma
Liver angiosarcoma
Scottish Terrier
List of dog diseases
Neutering
White-crowned parrot
Flat-coated Retriever
Vizsla
Polyvinyl chloride
Golden Retriever
Freeze brand
Cancer in dogs
Theodore K. Lawless
List of skin conditions
777 Charlie
List of MeSH codes (C04)
Dog
International Classification of Diseases for Oncology
Index of oncology articles
Leonberger
Mastocytoma in dogs
Hemangiosarcoma - Wikipedia
Skin Cancer (Hemangiosarcoma) in Cats | PetMD
AKC Canine Health Foundation | Mapping Genes Associated with Canine Hemangiosarcoma
early-detection-and-strategic-prevention-of-canine-hemangiosarcoma-an-update-on-the-shine-on-project | Smiling Blue Skies
Assessing How a Protein Helps Hemangiosarcoma Cells Survive - PWD Foundation, Inc.
View of Use of Acrylic Resin to Fill the Orbital Cavity after Exenteration in a Dog with Conjunctival Hemangiosarcoma
Go to In vitro effects of Yunnan Baiyao on canine hemangiosarcoma cell lines.
Hemangiosarcoma in Dogs
Hemangiosarcoma is Blood or Skin Cancer in Dogs and Cats - Veterinary Partner - VIN
hemangiosarcoma in dogs leg
Can Hemangiosarcoma be prevented?
Hemangio Sarcoma Archives - WENDRA'S WELLNESS
3 Facts about Hemangiosarcoma (HSA)
hemangiosarcoma Archives - Oh My Dog!
Hemangiosarcoma and Our Dogs - NaturalPet.Health
Splenic Hemangiosarcoma Case Study: Pita - FidoCure
hemangiosarcoma dog treatment Archives - Dog Carely
When To Euthanize a Dog With Hemangiosarcoma?
Can a dog survive hemangiosarcoma? - Lyotomachida.net
Hemangiosarcoma Symptoms and Diagnosis in Dogs - Sahibimi Ariyorum
Hemangiosarcoma In Large Dogs | Best Friends Veterinary Center
Labrador Retriever Dog Breed Health and Care | PetMD
Hemangiosarcoma: Cancerous Tumour on the Spleen or Benign Tumour? - GemePet
When To Euthanise A Dog With Hemangiosarcoma | Cloud 9 Vets
Yunnan Baiyao for Dogs with Hemangiosarcoma - Drake Dog Cancer Foundation
Cutaneous Hemangiosarcoma in Cats - Causes, Treatment and Associated Conditions - Vetster (GB)
How to prepare for end of life due to lymphoma in a canine? - Questions & Answers | VetInfo/QA
Anticancer effects of resveratrol in canine hemangiosarcoma cell lines - Fingerprint - Experts@Minnesota
Tumors5
- Hemangiosarcoma (HSA), a malignant tumor of vascular endothelial cells, is a significant health concern in dogs, with an incidence of ~2% of all tumors. (akcchf.org)
- Hemangiosarcoma, often abbreviated HSA or hemangio, are tumors thought to arise from vascular endothelial cells. (dogcancer.com)
- The most common places for hemangiosarcoma tumors are the spleen, heart, and skin, but they can occur anywhere in the body. (caninetricks.com)
- Hemangiosarcoma is a malignant cancer that often affects dogs and can lead to severe complications, such as bleeding tumors and a high risk of metastasis . (dogcancerfoundation.org)
- One of the primary concerns for dogs with hemangiosarcoma is internal bleeding from tumors. (dogcancerfoundation.org)
Dogs51
- Hemangiosarcoma is a rapidly growing, highly invasive variety of cancer that occurs almost exclusively in dogs, and only rarely in cats, horses, mice, or humans (vinyl chloride toxicity). (wikipedia.org)
- Hemangiosarcoma is quite common in dogs, and more so in certain breeds including German Shepherds and Golden Retrievers. (wikipedia.org)
- Dogs with hemangiosarcoma rarely show clinical signs until the tumor has become very large and has metastasized. (wikipedia.org)
- Owners of the affected dogs often discover that the dog has hemangiosarcoma only after the dog collapses. (wikipedia.org)
- found a five times greater risk of cardiac hemangiosarcoma in spayed vs. intact female dogs and a 2.4 times greater risk of hemangiosarcoma in neutered dogs as compared to intact males. (wikipedia.org)
- Dogs rarely show symptoms of hemangiosarcoma until after the tumor ruptures, causing extensive bleeding. (wikipedia.org)
- Canine hemangiosarcoma is a common and highly fatal cancer in dogs. (pwdfoundation.org)
- It has been utilized in the veterinary profession to control bleeding in dogs with hemangiosarcoma (HSA) and has been anecdotally reported to prolong survival times in dogs with this neoplasm. (fitzpatrickreferrals.co.uk)
- The signs of hemangiosarcoma in dogs are related to blood loss. (dogcancer.com)
- Without treatment, dogs have days to weeks to live with visceral or heart hemangiosarcoma. (dogcancer.com)
- The median age dogs are diagnosed with hemangiosarcoma is ten years of age. (dogcancer.com)
- These cells line the arteries, veins, and capillaries, so hemangiosarcoma in dogs can occur anywhere there are blood vessels. (dogcancer.com)
- Whatever the original cell involved, there are several possible locations where you might see hemangiosarcoma in dogs. (dogcancer.com)
- While every case is different, some known facts exist about hemangiosarcoma in dogs. (dogcancer.com)
- Hemangiosarcoma is most common in middle-aged and older dogs, with the median age at diagnosis being ten years. (dogcancer.com)
- Hemangiosarcoma accounts for 5% of all visceral neoplasms 3 (organ cancers) and about 50% of splenic malignancies (spleen cancers) in dogs. (dogcancer.com)
- Hemangiosarcoma is the most common heart cancer, accounting for 40% of all heart cancers in dogs. (dogcancer.com)
- There is likely a genetic component for hemangiosarcoma since it is seen more commonly in certain purebred dogs. (dogcancer.com)
- hemangiosarcoma in dogs, what are end stages of hemangiosarcoma in dogs, stage 1 hemangiosarcoma in dogs, symptoms of hemangiosarcoma in dogs, hemangiosarcoma in dogs treatment Boxers are statistically more prone to hemangiosarcoma. (dogcancer.com)
- Hemangiosarcoma is most common in purebred Golden Retrievers, Boxers, German Shepherd Dogs, and Labrador Retrievers . (dogcancer.com)
- Hemangiosarcoma is a common tumor in dogs but we have included feline information at the end of this article. (vin.com)
- Tissue samples of dogs with hemangiosarcoma show that 73% of them were infected with Bartonella. (peytongoldens.com)
- The article 'Hemangiosarcoma Awareness: Protecting Your Dog's Health and Well-being' provides valuable information about the prevalence, signs, and risk factors of hemangiosarcoma in dogs. (dogcarely.com)
- Hemangiosarcoma is a very aggressive cancer in dogs with high mortality rate and median survival of 3-6 months with a ten percent one-year survival rate [1]. (lyotomachida.net)
- Even when a tumor is quickly detected and removed, the outlook for dogs with hemangiosarcoma is grim. (lyotomachida.net)
- Surgery is the primary method of treatment for most dogs with hemangiosarcoma, regardless of the location of the primary tumor. (lyotomachida.net)
- How aggressive is hemangiosarcoma in dogs? (lyotomachida.net)
- What does hemangiosarcoma look like in dogs? (lyotomachida.net)
- Is there a cure for hemangiosarcoma in dogs? (lyotomachida.net)
- Hemangiosarcoma (HSA) is one of the most aggressive cancers out there with a very low survival rate by the time it is detected in our dogs. (lyotomachida.net)
- Hemangiosarcoma treatments in dogs have previously only extended the life of a dog few months. (lyotomachida.net)
- Is there a higher risk for female dogs with hemangiosarcoma? (lyotomachida.net)
- Hemangiosarcoma is a cancerous tumor usually only treated with surgery, but around 30 percent of dogs can have a recurrence. (caninetricks.com)
- Dogs with Hemangiosarcoma will generally live from one to three months from the time of diagnosis. (caninetricks.com)
- Hemangiosarcoma typically occurs in older dogs because they have been exposed to more ultraviolet light, a risk factor for the condition. (caninetricks.com)
- The median survival time for dogs with splenic hemangiosarcoma with surgery is 141 days, while the median survival time for those without surgery is only 21 days. (caninetricks.com)
- Dogs with hemangiosarcoma may have no symptoms at all, or they may show various symptoms, depending on the stage of their disease. (caninetricks.com)
- What are end stages of hemangiosarcoma in dogs? (caninetricks.com)
- The end-stage hemangiosarcoma in dogs involves the spread of cancer (called metastasis). (caninetricks.com)
- In addition, the terminal stage of hemangiosarcoma in dogs occurs when the dog's body can no longer overcome the effects of the disease. (caninetricks.com)
- Hemangiosarcoma is a common cancer of older, large breed dogs. (bestfriendsvet.com)
- The diagnosis of hemangiosarcoma in dogs is made by the veterinarian using various methods. (sahibimiariyorum.com)
- Treatment of hemangiosarcoma in dogs, to the stage of the cancer may vary depending on the residence and the general health of the dog. (sahibimiariyorum.com)
- In this blog post, we will explore the potential benefits of Yunnan Baiyao for dogs with hemangiosarcoma . (dogcancerfoundation.org)
- Hemangiosarcoma is an aggressive form of cancer that primarily affects the blood vessels and spleen in dogs. (dogcancerfoundation.org)
- Yunnan Baiyao has gained attention in recent years as a complementary treatment for dogs with hemangiosarcoma due to its ability to reduce bleeding and potentially slow down the progression of the disease. (dogcancerfoundation.org)
- Yunnan Baiyao is a promising complementary treatment for dogs with hemangiosarcoma due to its ability to control bleeding, reduce inflammation , and provide pain relief. (dogcancerfoundation.org)
- Hemangiosarcoma is a fairly common form of cancer in dogs, particularly in larger breeds, like German Shepherds, Golden Retrievers, and Labradors. (gemepet.com)
- Hemangiosarcoma (HSA), a locally invasive and highly metastatic endothelial cell neoplasm, accounts for two-thirds of all cardiac and splenic neoplasms in dogs. (lymeresourcecentre.com)
- Dr. Selting's study also measured serum concentrations of vitamin D in 62 dogs presenting with blood in their abdominal cavities as a result of various cancers such as hemangiosarcoma and splenic malignancies, and compared them to 282 dogs without cancer. (animalwellnessmagazine.com)
- CLINICAL RELEVANCE Primary nodal hemangiosarcoma in dogs is a rare and, to the authors' knowledge, previously undescribed disease that appears to develop in the cervical lymph nodes as a slow-growing mass or masses. (avma.org)
Stages of hemangiosarcoma3
- The end stages of hemangiosarcoma are usually related to blood loss, in which case you will see signs of shock and weakness or complications from metastasis. (dogcancer.com)
- There may be no noticeable symptoms in the early stages of hemangiosarcoma, which is one reason we don't often catch this cancer early . (dogcancer.com)
- In the early stages of hemangiosarcoma, surgical intervention may be an option for tumor removal. (sahibimiariyorum.com)
Spleen8
- Hemangiosarcoma of the spleen or liver is the most common tumor to cause hemorrhage in the abdomen. (wikipedia.org)
- The most common locations for primary hemangiosarcoma include the spleen, the right atrium of the heart, the liver, and subcutaneous (under the skin) tissues. (dogcancer.com)
- While a splenectomy (removal of the spleen) certainly ends the prospect of this type of life-threatening sudden bleed, splenic hemangiosarcoma is still a rapidly spreading malignancy. (vin.com)
- Veterinarians can diagnose spleen hemangiosarcoma after an acute episode of fainting in a dog, or weakness after a tumor rupture. (sahibimiariyorum.com)
- Usually, splenic hemangiosarcoma is diagnosed when the veterinarian feels an enlarged spleen or incidentally discovers a mass in the spleen during an X-ray or ultrasound. (sahibimiariyorum.com)
- Cardiac hemangiosarcoma is often discovered with other types of hemangiosarcoma, particularly in the spleen. (sahibimiariyorum.com)
- Hemangiosarcoma: Cancerous Tumour on the Spleen or Benign Tumour? (gemepet.com)
- Hemangiosarcoma is a cancerous tumour that grows on the spleen. (gemepet.com)
Golden retrievers2
- New research suggests that, yes, hemangiosarcoma in our beloved Golden Retrievers can be prevented. (peytongoldens.com)
- One in five Golden Retrievers currently die of hemangiosarcoma! (peytongoldens.com)
Cancers2
- Like many cancers, the cause of hemangiosarcoma is unknown, and there is no one cause. (dogcancer.com)
- Bone Cancer (Osteosarcoma) and Hemangiosarcoma are in the top five most common dog cancers. (wearethecure.org)
Form of hemangiosarcoma2
- Because the subcutaneous form of hemangiosarcoma wants to spread, staging is a good idea to determine the extent of the disease. (vin.com)
- The skin form of hemangiosarcoma are the most easily removed surgically and have the greatest potential for complete cure. (lyotomachida.net)
Forms of hemangiosarcoma2
Types of hemangiosarcoma1
- Are there different types of hemangiosarcoma? (cloud9vets.co.uk)
Cause of hemangiosarcoma1
- Although the cause of hemangiosarcoma of the skin is unknown, it is known that light colored and short coated cats are more predisposed to skin cancer than others. (petmd.com)
Metastatic2
- Furthermore, hemangiosarcoma is highly malignant and metastatic, spreading throughout the body to internal organs. (caninetricks.com)
- Necropsy findings and negative immunohistochemical staining for lymphatic vessel endothelial receptor-1 were consistent with a metastatic mesenteric hemangiosarcoma. (tamu.edu)
Blood vessels5
- Hemangiosarcoma is a frightening and devastating cancer of the blood vessels. (dogcancer.com)
- Hemangiosarcoma is a type of cancer of blood vessels. (vaduvavetservices.com)
- In simpler words, think of hemangiosarcoma (HSA) as cancer of the blood vessels. (caninetricks.com)
- Cutaneous hemangiosarcoma (HSA) is a rare malignant skin cancer in cats that arises from abnormal cells within blood vessels. (vetster.com)
- Angiosarcoma and hemangiosarcoma, which develop in the liver's blood vessels. (healthnews.com)
Endothelial cells2
Visceral2
- Occasionally, hemangiosarcoma of the skin can be a metastasis from visceral hemangiosarcoma. (wikipedia.org)
- Tumor-associated macrophages in canine visceral hemangiosarcoma. (bvsalud.org)
Causes Hemangiosarcoma1
- What Causes Hemangiosarcoma? (dogcancer.com)
Yunnan Baiyao2
- Inflammation can exacerbate the symptoms of hemangiosarcoma , so reducing inflammation with Yunnan Baiyao could potentially slow down the disease's progression. (dogcancerfoundation.org)
- It is essential to note that Yunnan Baiyao should not be considered a cure for hemangiosarcoma , but rather a complementary treatment that may improve your dog's overall well-being while they undergo conventional treatments. (dogcancerfoundation.org)
Life-expectancy2
- What is the life expectancy of a dog with hemangiosarcoma? (lyotomachida.net)
- What is hemangiosarcoma life expectancy? (cloud9vets.co.uk)
Subcutaneous3
- The dermal hemangiosarcoma has a fair prognosis as long as it is removed before it can invade to the subcutaneous tissues. (vin.com)
- The overlying skin is often totally normal on top of a subcutaneous hemangiosarcoma and often the surgeon is surprised to find a dark blood-red growth under the skin when the tumor is removed. (vin.com)
- A subcutaneous hemangiosarcoma should be treated as cancer and an oncologist should be consulted for therapy beyond surgical removal. (vin.com)
Symptoms5
- The first symptom of hemangiosarcoma is frightening and potentially life-threatening: a tumor ruptures and the dog begins showing symptoms of blood loss. (dogcancer.com)
- The signs and symptoms of hemangiosarcoma depend on the disease's location and stage. (dogcancer.com)
- Are there any signs or symptoms of hemangiosarcoma? (lyotomachida.net)
- Unfortunately, no clinical signs (symptoms) are classic for hemangiosarcoma other than sudden, profound, internal bleeding. (lyotomachida.net)
- The most common symptoms of hemangiosarcoma are lethargy and loss of appetite. (caninetricks.com)
Metastasis1
- Abdominal and thoracic X-rays will be taken to determine how invasive the hemangiosarcoma is, whether there is metastasis in the lungs or any other internal organs. (petmd.com)
Malignant cancer1
- The secret lies in the connection between a bacteria called bartonella and the highly malignant cancer, hemangiosarcoma. (peytongoldens.com)
Diagnosis3
- With the exception of the skin form - which can often be eliminated by surgery - a diagnosis of hemangiosarcoma is bad news. (vin.com)
- With a combination approach that included FidoCure ® therapy, Pita has lived for a year following a hemoabdomen and diagnosis of splenic hemangiosarcoma. (fidocure.com)
- Histopathologic examination and immunohistochemistry supported a diagnosis of hemangiosarcoma. (tamu.edu)
Lymph node2
- Lymph node aspiration: When there is a possibility of spread of hemangiosarcoma to lymph nodes, lymph node aspiration can be performed. (sahibimiariyorum.com)
- Histologic examination of the excised tissue revealed a completely excised grade 1 or 2 lymph node hemangiosarcoma. (avma.org)
Aggressive cancer2
- Hemangiosarcoma is an aggressive cancer which spreads quickly to other areas such as lungs, liver and brain. (gemepet.com)
- Background: Canine hemangiosarcoma (HSA) is an aggressive cancer arising from multipotential bone marrow-derived stem cells. (uky.edu)
Dermal1
- The biggest problem with the dermal hemangiosarcoma is that it frequently arises in multiple spots within a broader expense of skin. (vin.com)
Survival3
- This study examines how a protein expressed by stem cells contributes to the maintenance and survival of hemangiosarcoma stem cells. (pwdfoundation.org)
- The prognosis is much better for skin hemangiosarcoma, with a stage 1 tumor having a median survival time of about 26 months. (dogcancer.com)
- To our knowledge, this is the first report to describe the use of debulking surgery and adjuvant doxorubicin chemotherapy in the treatment of mesenteric hemangiosarcoma resulting in extended survival in a cat. (tamu.edu)
Cancer4
- With hemangiosarcoma, cancer tends to be highly aggressive and often spreads. (caninetricks.com)
- Hemangiosarcoma (HSA) is cancer composed of hemangiosarcoma cells. (caninetricks.com)
- Hemangiosarcoma is a relatively deadly cancer most often classified separately from other soft tissue sarcomas because of its more aggressive behavior. (wearethecure.org)
- The occupational etiology of a very rare cancer due to a specific agent (e.g., hemangiosarcoma of the liver due to vinyl chloride) is much more readily documented than the occupational etiology of a cancer type potentially caused by several factors (e.g., lung cancer associated with exposure to chromates). (cdc.gov)
Doxorubicin1
- Use of doxorubicin chemotherapy following debulking surgery in the treatment of a cat with mesenteric hemangiosarcoma. (tamu.edu)
Liver2
- Tests such as liver function tests, blood cell counts, and biochemical analyzes can help evaluate the signs and effects of liver hemangiosarcoma. (sahibimiariyorum.com)
- During the diagnostic review process for splenic hemangiosarcoma, veterinarians typically closely evaluate the liver, lungs, and heart, which are common sites where hemangiosarcoma has spread. (sahibimiariyorum.com)
Dog's2
- When to euthanize a dog with hemangiosarcoma varies from canine to canine and depends on the dog's overall health. (caninetricks.com)
- Surgical Examination: Sometimes surgical examination may be required to diagnose a dog's hemangiosarcoma. (sahibimiariyorum.com)
Surgery1
- What kind of surgery is needed for hemangiosarcoma? (lyotomachida.net)
Common1
- When To Euthanise A Dog With Hemangiosarcoma is an all-too-common question we get asked. (cloud9vets.co.uk)
Cats2
Time is of t2
- Other clinical signs sometimes reported by owners include: Most pet owners are quick to act in cases of sudden collapse and time is of the essence in cases of hemangiosarcoma. (lyotomachida.net)
- In addition, the decision to euthanize a beloved dog is difficult, but when it comes to hemangiosarcoma, pet lovers should also realize that time is of the essence. (caninetricks.com)
Lungs1
- Chest radiographs: hemangiosarcoma tends to spread to the lungs. (vin.com)
Biopsy1
- A biopsy will confirm any masses are hemangiosarcoma. (cloud9vets.co.uk)
Treatment1
- Using all these methods together, the veterinarian can diagnose the presence of hemangiosarcoma in the dog, evaluate the extent of the cancer's spread, and determine the appropriate treatment plan. (sahibimiariyorum.com)
Skin2
- Hemangiosarcoma of the skin usually appears as a small red or bluish-black lump. (wikipedia.org)
- It is suspected that in the skin, hemangiosarcoma is caused by sun exposure. (wikipedia.org)
Signs2
- What are the signs my dog is dying from hemangiosarcoma? (cloud9vets.co.uk)
- If the greater chance is that your dog has hemangiosarcoma then you'll avoid the trauma of profuse bleeding, signs of shock, and collapse if you have your dog put to sleep. (cloud9vets.co.uk)
Ultrasound1
- Even a small splenic hemangiosarcoma should be detectable with ultrasound. (vin.com)